#=GF ID GAAD
#=GF AC PF19976.3
#=GF DE GTPase-associated adaptor domain
#=GF AU Aravind L;0000-0003-0771-253X
#=GF AU Iyer LM;0000-0002-4844-2022
#=GF SE Aravind L
#=GF GA 23.60 23.60;
#=GF TC 23.60 23.60;
#=GF NC 22.20 21.40;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP Domain
#=GF RN [1]
#=GF RM 32101166
#=GF RT Highly regulated, diversifying NTP-dependent biological conflict
#=GF RT systems with implications for the emergence of multicellularity.
#=GF RA Kaur G, Burroughs AM, Iyer LM, Aravind L;
#=GF RL Elife. 2020; [Epub ahead of print]
#=GF DR INTERPRO; IPR045533;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC Adaptor domain in the GTPase-centric systems of NTP-dependent
#=GF CC conflict systems that directly couples the effector to the GAP1
#=GF CC component.
#=GF SQ 53
#=GS A0A1T4VMD6_9GAMM/365-427 AC A0A1T4VMD6.1
#=GS A0A0Q5VEN5_9HYPH/373-435 AC A0A0Q5VEN5.1
#=GS W8EHC8_9CAUD/1-61 AC W8EHC8.1
#=GS A0A0T2YGH0_9BURK/384-445 AC A0A0T2YGH0.1
#=GS A0A2C6DR23_9GAMM/369-430 AC A0A2C6DR23.1
#=GS A0A1G6LRV0_9BURK/369-431 AC A0A1G6LRV0.1
#=GS A0A4Q9GJL4_9HYPH/1137-1198 AC A0A4Q9GJL4.1
#=GS A0A2Z5G5I6_9BACT/4-65 AC A0A2Z5G5I6.1
#=GS A0A157S9E0_9BORD/7-69 AC A0A157S9E0.1
#=GS A0A7S7YBZ9_9CAUD/1-61 AC A0A7S7YBZ9.1
#=GS A0A2L0VS14_9SPHN/404-466 AC A0A2L0VS14.1
#=GS A0A4Y9SY38_9BURK/383-445 AC A0A4Y9SY38.1
#=GS A0A3D9Z396_9HYPH/369-431 AC A0A3D9Z396.1
#=GS A0A848LCT8_9DELT/370-431 AC A0A848LCT8.1
#=GS A0A212DUX2_9HYPH/75-137 AC A0A212DUX2.1
#=GS A0A1M5YEI6_9FIRM/380-441 AC A0A1M5YEI6.1
#=GS A0A495J0B9_9SPHI/373-435 AC A0A495J0B9.1
#=GS A0A6L9MLJ1_9HYPH/364-425 AC A0A6L9MLJ1.1
#=GS A0A845AA74_9SPHN/405-466 AC A0A845AA74.1
#=GS A0A1X4ISQ9_9RHOB/360-421 AC A0A1X4ISQ9.1
#=GS A0A5J6N0P7_9PROT/370-431 AC A0A5J6N0P7.1
#=GS A0A181C660_9PROT/380-442 AC A0A181C660.1
#=GS A0A0Q4XIS2_9BURK/22-83 AC A0A0Q4XIS2.1
#=GS A0A7R7HDJ9_9HYPH/366-428 AC A0A7R7HDJ9.1
#=GS A0A0X7BF18_9FLAO/308-369 AC A0A0X7BF18.1
#=GS A0A0F4QZM6_9GAMM/357-418 AC A0A0F4QZM6.1
#=GS A0A327JN21_9HYPH/362-423 AC A0A327JN21.1
#=GS C5SZD0_ACIDE/370-431 AC C5SZD0.1
#=GS A0A7C9QT75_9PROT/379-441 AC A0A7C9QT75.1
#=GS A0A7C9RCL0_9BRAD/169-231 AC A0A7C9RCL0.1
#=GS A0A7H0XFV1_9CAUD/2-62 AC A0A7H0XFV1.1
#=GS A0A072TE28_MEDTR/380-442 AC A0A072TE28.1
#=GS A0A2M8N139_9RHOB/343-404 AC A0A2M8N139.1
#=GS A0A0F2J805_9FIRM/368-429 AC A0A0F2J805.1
#=GS A0A418W7Y8_9SPHN/379-441 AC A0A418W7Y8.1
#=GS A0A857J475_9BURK/356-417 AC A0A857J475.1
#=GS A0A841JBB7_9SPHN/372-433 AC A0A841JBB7.1
#=GS A0A1H9RLI8_9BURK/267-328 AC A0A1H9RLI8.1
#=GS A0A1H7L9Z0_9BURK/387-449 AC A0A1H7L9Z0.1
#=GS A0A6G7YY64_9GAMM/368-430 AC A0A6G7YY64.1
#=GS A0A1H9K5Z3_9RHOB/360-421 AC A0A1H9K5Z3.1
#=GS A0A090VMW1_PSEVU/391-453 AC A0A090VMW1.1
#=GS A0A4R2GHA8_9HYPH/381-442 AC A0A4R2GHA8.1
#=GS A0A103EN81_9BURK/371-432 AC A0A103EN81.1
#=GS B2JXC3_PARP8/362-423 AC B2JXC3.1
#=GS A0A7W9BVM8_9SPHN/379-441 AC A0A7W9BVM8.1
#=GS I8HWI6_9GAMM/371-433 AC I8HWI6.1
#=GS A0A0L7T178_9GAMM/380-442 AC A0A0L7T178.1
#=GS A0A1I6IWK4_9BURK/398-460 AC A0A1I6IWK4.1
#=GS A0A1H4GQB1_9BACT/198-259 AC A0A1H4GQB1.1
#=GS A0A345QB97_9RHOB/368-429 AC A0A345QB97.1
#=GS A0A2S0N6F4_9BURK/384-445 AC A0A2S0N6F4.1
#=GS A0A2G3K0I1_9BURK/384-445 AC A0A2G3K0I1.1
A0A1T4VMD6_9GAMM/365-427 .vs--KSVAFLFQ.ELSGSSQRKILDEIGLLTDEEwKTRSGVELQVIAFHRASEQNRFDQLKHMIF-a...
A0A0Q5VEN5_9HYPH/373-435 ...EYQNLYLRFFrDLAEGDRLRILVDLGAIPAGL.NANFNHETESRLLRNIVKSGRFDDLKFTVN-d...
W8EHC8_9CAUD/1-61 .mn--RELAHAFS.QLRVSQRTTVLQDINLNLHQA.KEESNNDFMKRCLEKIACAGLIRELEAA---ml..
A0A0T2YGH0_9BURK/384-445 .sp--RNLIFRFW.DLSIAERRDIMLKLDLIDVAE.LRVPEPELYKKAFKLAATRGLLADLASEIE-r...
A0A2C6DR23_9GAMM/369-430 ...KLRIVSVRFY.KLTLSQKLTIARKLGLLEDED.RDQSNFERFRRVFILAQQRDLIGELDNEIS-t...
A0A1G6LRV0_9BURK/369-431 ...AYRDLYMRFFrDLSDGARLQLLAVLGVVPGDF.SGHLNHGAESRLFNIVVRQGRFSELSALIHE....
A0A4Q9GJL4_9HYPH/1137-1198 ..r-LRELGIRFY.GLTFSQKSEIVGRLALLEDND.IAQPDFERFRRVFIRASERGKLADLEQAITE....
A0A2Z5G5I6_9BACT/4-65 ..n-RKKLLYAFV.ALPYHTRLSIMEQLKLIDEDN.RGLPDNERFASCFDRAEKQNRLNDVWDLVE-s...
A0A157S9E0_9BORD/7-69 ..g-YETARLRFFrDLLEGERVRILVELDALPEKS.DERMSQGLERRLFDLLVKEGRLKDVERMINK....
A0A7S7YBZ9_9CAUD/1-61 .mn--RELVHAFT.KLRVSERTSVMQDLNLNLHQA.REESNNDYMKRCLEKIACAGLIRELEAA---ml..
A0A2L0VS14_9SPHN/404-466 .rf--AELRLKYFhSLTPLQRLEILVDLAILPSDW.SGSLTSALELSAIEAIAGMGRLDDLEEAI--gk..
A0A4Y9SY38_9BURK/383-445 ..g-YEIARLRFFrDLLEGERLRILVELDALPENS.DERMSQGLERRLFDMLVRNGKLAEVKKMIDQ....
A0A3D9Z396_9HYPH/369-431 ..e-FALVLLRFFrDLSPGQRVRVLVRLGALPSDW.SEDLSHGIERQVVDQLESADRLHELSQAIDW....
A0A848LCT8_9DELT/370-431 .ne--RRLTYRFL.TLPFRHQITVAKNLDVLTDAD.RGLSDEALFRVLFKRAAEKGILGKLWAETEK....
A0A212DUX2_9HYPH/75-137 rfa---MVLLRFFrDLSPSQRIQILVRLEALPPTW.NGAMTHGMERTVVDKLMKDGRLAHLEAEIK-r...
A0A1M5YEI6_9FIRM/380-441 .ne--RELIYGFY.ELSVVRQLELLGELELLSEDD.KGKSMTSVLNSVIQRSKEQGKFRLLWNSIE-n...
A0A495J0B9_9SPHI/373-435 ...EYQLVLLKYFrDLSRAQRLSVLIDFGAIPQNW.TDRLTHSVERTVFDKLVQDGKLQQIHEKINQ....
A0A6L9MLJ1_9HYPH/364-425 .sa--RIVASKMF.RLAEHVQRQIIVHLSLDQDGD.QGLKDYEFVLAAVNRAKSQNRLPALNEMTDE....
A0A845AA74_9SPHN/405-466 ..d-TRDLQIRFFqLLDDEQRRAAFVAFGIIRQA-.QGRMDHSMERRLFRRAVRQGRADEIERM---las.
A0A1X4ISQ9_9RHOB/360-421 ...SLRTLSIRYF.KLTFSKKLEIAGSLELFEEAD.TKLPDHERFRRVLLRARERNLLDELKAAID-a...
A0A5J6N0P7_9PROT/370-431 ..e-YPLLLLRFFrDLTSSERLAILVKLGALPTDW.AEPLTHSIERRALDTLSRKGRIREVEECI--a...
A0A181C660_9PROT/380-442 ..g-YELALLRFFrDLVESERLRILVELDAIPSDF.DERMTQGVERRLFDWLVSERRLPDVTAMIEK....
A0A0Q4XIS2_9BURK/22-83 ...STDNLVFRFW.QLSGSQMRDIALELGLITKAD.LKVPPHQRYHSALKLAREKGLLVELAKEIEK....
A0A7R7HDJ9_9HYPH/366-428 rfa---MVLLRFFrDLSPTQRMRILVRLGALPPTW.RGTMIHGMERTVVDKLMKDGRLGQLEAEID-r...
A0A0X7BF18_9FLAO/308-369 ..a-VQLTVAAFL.ELSSYQKAEVIDSLDLSLNNF.INLSAHEMNKELFRQVRERNLLPALWNAINN....
A0A0F4QZM6_9GAMM/357-418 .dn--SNIVGRFI.SLTESSKREILKRLGIYEVSS.STLPSRINYEEALKSISEKGLKKQFIELII-e...
A0A327JN21_9HYPH/362-423 ...SLRALSLKYF.KLTFSKKLAIAGKLNLLEEED.TKLPDYERFRQVLLRARERGLLIEFETEID-g...
C5SZD0_ACIDE/370-431 ...STRHLVDRFW.DLDGSDRREIALELGLITDGE.INLPEPQRYGVALIRASERGLLNQLEQLVNA....
A0A7C9QT75_9PROT/379-441 ..g-YELTLLRFFrDLLENERLRILVELNAIPADS.DERMTQGVERKLFDWLAREGRLLELDRMIDK....
A0A7C9RCL0_9BRAD/169-231 ..g-YRLVLLRFFrDLTEGERLRLLVELGAVPSGS.DERMTQAAQRHLLDWLVREGKIGDVERLIS-d...
A0A7H0XFV1_9CAUD/2-62 nsp----VIQAFL.ALRMSQRLAVAQRLNVCMSQG.DHEAGDKYAIRILQAIEKNGLMRELESE---lre.
A0A072TE28_MEDTR/380-442 ..g-YELALLRFFrDLVESERLRILVELDAIPPDF.DERMTQGVERMLFDWLVVHLRITGLVP----sndd
A0A2M8N139_9RHOB/343-404 ..a-TKHLVDRFW.DLDASDRREIALELGLISEGE.VDLPELQRYGVALIRASERNLLDQLEKLVK-v...
A0A0F2J805_9FIRM/368-429 ...NLRDLIYKFF.DLSYIRQTEILVGLNLLDDDD.RGKRYSNIISKIIDKAELHNQMRELWDEINK....
A0A418W7Y8_9SPHN/379-441 ..a-FEELRLLFWqRLSQTERVDIFIGLGLLTEAA.RGRLPSAIERKAFEDASATGMLGQLWDKTM-a...
A0A857J475_9BURK/356-417 ..q-LRKVGLRFY.QLSFSKKSEIAGRFGLLEDED.INQPDYERFRRVFQRAHQRGLIDDLAEAIR-n...
A0A841JBB7_9SPHN/372-433 ..t-TRNLVYRFW.KLTSSQRRDIAADLGLLEEEE.MALLEPERYGRALLRAGERGLVDALGAEIKK....
A0A1H9RLI8_9BURK/267-328 ...KTRHLVDRFW.DLDGSDRREIALGLGLITDEE.INLPEPQRYGVALIRAAERGLLDQLEQLINE....
A0A1H7L9Z0_9BURK/387-449 ..d-QRLLQLRFFqELPEGERLKALVNLGAIPGDL.KGRLDHSMERRLFRMLIKQGKARAIEALLD-l...
A0A6G7YY64_9GAMM/368-430 ..d-VRLVRLRFFrDLPEDGRRRILVELDVIPADL.TDRLDHTIEQRFFAKLVAQGRLGELSAAID-a...
A0A1H9K5Z3_9RHOB/360-421 ...SLRTLSIRYF.KLTFSKKLEIAGSLDLFEEAD.TKLPDHERFRRVLLRARERDLLDELKAAID-a...
A0A090VMW1_PSEVU/391-453 ...SYEIARLRFFrDLFEGERLRILVELGALSENF.NERMNQGIERKLLDLLVREGKLEGIENMIDQ....
A0A4R2GHA8_9HYPH/381-442 ...SLRDLGLRFY.RLSFSKKSEIAGRLELLEEED.MRQPDYERFRRVLLRANERSQLNELSAAV--ra..
A0A103EN81_9BURK/371-432 ..t-VRSVTIKFF.KLKEHEQRRVIANLELDREDD.RNLKDYEVAINAVRRSQENGKLQLLNDLVEE....
B2JXC3_PARP8/362-423 ...SMRRIVNEFF.RLSISRKSAIAGALDLLEESE.RGLPEVQRFTRALERAREGGKLAQLWQMTNE....
A0A7W9BVM8_9SPHN/379-441 ..g-YELAMLRFFrNLYEGERLRILVELDALPVGS.DERMNQGLELRLFDWLARAGKLPEAVAMID-r...
I8HWI6_9GAMM/371-433 ...KYAQLRLTFFrDLTATQRISVLVKLNALPPQW.QDTLMHSAEQQILDSLHLTNRLAELEAAMNE....
A0A0L7T178_9GAMM/380-442 ..g-YETARLKFFrDLFETERLRILVELEALPSGS.NDPITQGLERKFFDMLIRNGKLAIVERLIDK....
A0A1I6IWK4_9BURK/398-460 ..s-VNELVFRFW.QLGAKRMRDVALELGLITSEEvMALPPHRRYEIAVERAVERGLLAELAEQVTK....
A0A1H4GQB1_9BACT/198-259 ..k-IEILVRAFL.RLSESQKLMIAKQLEIFEDRF.ITLSSKELTQEVFRRAREKSLLAELWDNVNK....
A0A345QB97_9RHOB/368-429 ..s--ANITLRFFrDLTANQRRQIFIENGLLPSDW.SEHMKHSVETLLFRQLLSKGNAAELEKLIIK....
A0A2S0N6F4_9BURK/384-445 ...STDNLIFRFW.QLRGSQMRDIALQLGLITKAD.LQVAPHERYHSVLKLAKEKGLLAELAKQIEK....
A0A2G3K0I1_9BURK/384-445 ...STDNLIFRFW.QLSSSQMRDIALELGLMTKDD.MQVPPHERYRNALNVAKQKGLLIELAKLIEK....
#=GC seq_cons ..t.hcplhhRFa.cLstupRhcIhlcLsllssst.pph.spph.cplhcphtccGhLs-LpphIp.....
//
