#=GF ID GARP
#=GF AC PF16731.9
#=GF DE Glutamic acid/alanine-rich protein of Trypanosoma
#=GF AU Coggill P;0000-0001-5731-1588
#=GF SE pdb_2y44
#=GF GA 27.40 27.40;
#=GF TC 28.50 28.50;
#=GF NC 27.30 27.30;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Domain
#=GF RN [1]
#=GF RM 21471223
#=GF RT Structural characterization and epitope mapping of the glutamic
#=GF RT acid/alanine-rich protein from Trypanosoma congolense: defining
#=GF RT assembly on the parasite cell surface.
#=GF RA Loveless BC, Mason JW, Sakurai T, Inoue N, Razavi M, Pearson TW,
#=GF RA Boulanger MJ;
#=GF RL J Biol Chem. 2011;286:20658-20665.
#=GF DR INTERPRO; IPR031987;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC GARP, or glutamic acid/alanine-rich protein, is one of a subset
#=GF CC of major surface molecules on Trypanosoma species. They are all
#=GF CC surface-orientated, immunodominant, and highly charged. GARP is
#=GF CC interesting as ts expression coincides with the loss and gain of
#=GF CC variant surface glycoprotein (VSG) molecules in the tsetse
#=GF CC vector. It has an extended helical bundle structure that is
#=GF CC homologous to the core surface structure of VSG, suggesting that
#=GF CC it might replace the bloodstream VSG as the trypanosomes
#=GF CC differentiate inside the tsetse vector after a blood-meal [1].
#=GF SQ 55
#=GS F9WN26_TRYVY/113-305 AC F9WN26.1
#=GS Q38CW0_TRYB2/38-223 AC Q38CW0.1
#=GS F9W3C7_TRYCI/41-225 AC F9W3C7.1
#=GS Q57U16_TRYB2/29-221 AC Q57U16.1
#=GS Q385U1_TRYB2/28-218 AC Q385U1.1
#=GS Q57XI0_TRYB2/239-418 AC Q57XI0.1
#=GS Q57XH8_TRYB2/239-429 AC Q57XH8.1
#=GS F9WN13_TRYVY/27-223 AC F9WN13.1
#=GS Q57U14_TRYB2/29-220 AC Q57U14.1
#=GS Q38CV3_TRYB2/38-223 AC Q38CV3.1
#=GS Q57U10_TRYB2/29-221 AC Q57U10.1
#=GS F9WEJ8_TRYCI/41-225 AC F9WEJ8.1
#=GS Q57Z47_TRYB2/32-225 AC Q57Z47.1
#=GS Q38CV1_TRYB2/38-223 AC Q38CV1.1
#=GS Q38CV6_TRYB2/38-223 AC Q38CV6.1
#=GS Q57X85_TRYB2/29-226 AC Q57X85.1
#=GS F9W3K3_TRYCI/27-147 AC F9W3K3.1
#=GS F9WE91_TRYCI/41-225 AC F9WE91.1
#=GS Q57U12_TRYB2/29-220 AC Q57U12.1
#=GS F9WH64_TRYCI/1-137 AC F9WH64.1
#=GS F9WC09_TRYCI/27-218 AC F9WC09.1
#=GS Q38CV9_TRYB2/38-223 AC Q38CV9.1
#=GS Q38CV7_TRYB2/38-224 AC Q38CV7.1
#=GS F9WM65_TRYVY/146-285 AC F9WM65.1
#=GS Q38CU9_TRYB2/38-223 AC Q38CU9.1
#=GS Q38CW1_TRYB2/38-223 AC Q38CW1.1
#=GS Q57XI0_TRYB2/27-218 AC Q57XI0.1
#=GS F9WC09_TRYCI/239-430 AC F9WC09.1
#=GS Q38CV8_TRYB2/38-223 AC Q38CV8.1
#=GS Q57U18_TRYB2/29-221 AC Q57U18.1
#=GS F9WC09_TRYCI/451-642 AC F9WC09.1
#=GS F9WE93_TRYCI/41-225 AC F9WE93.1
#=GS F9WP06_TRYVY/468-654 AC F9WP06.1
#=GS F9WM12_TRYVY/113-305 AC F9WM12.1
#=GS F9WE90_TRYCI/41-225 AC F9WE90.1
#=GS F9WH65_TRYCI/27-218 AC F9WH65.1
#=GS Q38CV5_TRYB2/38-224 AC Q38CV5.1
#=GS Q38CV2_TRYB2/38-223 AC Q38CV2.1
#=GS F9WE92_TRYCI/41-225 AC F9WE92.1
#=GS F9WH65_TRYCI/451-642 AC F9WH65.1
#=GS F9WA19_TRYCI/37-229 AC F9WA19.1
#=GS F9WV46_TRYVY/145-284 AC F9WV46.1
#=GS F9WC08_TRYCI/50-241 AC F9WC08.1
#=GS F9WVM2_TRYVY/600-786 AC F9WVM2.1
#=GS F9WIZ4_TRYCI/34-228 AC F9WIZ4.1
#=GS F9WDT3_TRYCI/37-242 AC F9WDT3.1
#=GS Q38CV4_TRYB2/38-225 AC Q38CV4.1
#=GS F9WQR4_TRYVY/145-284 AC F9WQR4.1
#=GS Q57YD8_TRYB2/239-418 AC Q57YD8.1
#=GS Q38CV0_TRYB2/38-224 AC Q38CV0.1
#=GS F9WH65_TRYCI/239-430 AC F9WH65.1
#=GS Q38CW2_TRYB2/38-223 AC Q38CW2.1
#=GS F9WA18_TRYCI/37-242 AC F9WA18.1
#=GS Q57XH8_TRYB2/27-218 AC Q57XH8.1
#=GS Q57YD8_TRYB2/27-218 AC Q57YD8.1
F9WN26_TRYVY/113-305 .........v-EEVKTMCVLLKQLRGVS.PSVEALVTRANNSLSTISRYKAKEDSALEEAR..RGGSN-----...ETVQKHESRATAVGNAYATAAAAVLSVPDLAANI............TAASTTIINEIVESLDDLEKSEASEE-..VKEAGRPCaAAPaDSGVTSQSLDGVREAIVKKaaedDDAEL...VEEANSVLGHLAAQLRELEAAVATA.AGAEADAKAAS-e.............
Q38CW0_TRYB2/38-223 .........v-EEIRASCEVAHQLRGLS.QTVTSAVETSAAASSKAFEAKVQAEEAVELAE..SKGLN-----...--VTKAKEAAVRATLAAEAAATAASNVEINAANI............AAVPWLERRQ-NTGWEVLTKCINLDDD..IKKMASKC.KSA.AEVVTAESISAALNDLGKT...fINEKT...REALRKESVEFHKELASLEEHVEEA.VRAQKRAEDAAA..............
F9W3C7_TRYCI/41-225 .........v-EEVQALCDMARQLRALE.TASQSAVAAVVSSAREASEAKERAEKAVERAK..SKKRG-----...--VDTATEAAARAAAAAQRAETVVSDARKHAADL............TAASKDAIETTDESLRLLATCEKADEP..IRTAAKKC.TGA.AAEVTSKSLESAFDALAEL....VPD-G...ADVIRMYGAVFVVRLKSLEDDVRTA.GEAKSEAEKAE-g.............
Q57U16_TRYB2/29-221 .........v-SHVSAACLFSEALHGIP.FGVKALKALAAANVSDASKAREGCQDAVRRAE..DASWNNPKAE...EAVGRARAALKEAESAENAAKTALSDVEQYAARA............PLLAAGKTAPIDDYLKSVAEDNSAAST..ARRIARGC.SLP.NRGVNSWVLTQAVESACAI....FMGEI...CRIARTRMVDLRAEYDQLEAAVRRA.GEARVAARAAES..............
Q385U1_TRYB2/28-218 .........l-AQVLTLCQITEQLRGLK.EVVMKIGPRAVEEALFTLKAKKRSEVSLRRAE..EAAERDRNAG...FAAERARLAYDSVCEAVEFAEYAATSIEGRASSL............LVIQEYYVPFLEDVMLRVGTDAEAAE-..AQEAAMSC.LQT.KRSVSPTSLSEAALELRVR....LGVRN...FRALRRDLHRAAFCLYSLKKTAAKI.ALARSSVEE---ie............
Q57XI0_TRYB2/239-418 .........l-NQTQAVCLMVEQYRGLK.GAVDAFTEQAVSRSAMVSKVEERSQADAKRP-..--GGH-----...--MDQVKRAVAEVAKAVSKAQNVFKKVSRYARNL............KSIRAHYLPLMENTLRKIAGNAA-DEK..AKKAAEVC.GGT.AWVVTPKSLDDMRKKLMDN....FP-NL...SERLESDTRVVSHMLEDLNTSTQLI.TIASIA------vrrke.........
Q57XH8_TRYB2/239-429 .........l-QQTQALCIAAEQYRALP.IFVSNIEEISKTMAQKAADAKIRSDNVVQLAE..E-ANEDGKGK...LLSQRVRETVNEIAEAAEAAEKAYRALTGHSVYM............KSVAAAYAGSLEKTLLSISQYAASQA-..TRKAAEAC.RET.AEVVTPKSLEDTKNGLFHS....IPAQS...SKRLKKDTAKLIESLTILHREYKQL.NAAMQYAQAAE-l.............
F9WN13_TRYVY/27-223 .........v-EGVHALCKVLQQLKGVP.SYIDNVEKTVRKDVESCEEAVAKSEASFQVVE..SIIAELENDT...GLEELFKSIEDERLKASGAADDAVLGLRQFQRSE............NEVVHVITLYKNYVMKKIEGKKEYANDpkVREAAKDC.TET.DYSVTVASLGEALKEFIDL....SPSDY...DTAIEKDVNLTISHIEFLESIAKRI.SEDVNEAVTAAAnv............
Q57U14_TRYB2/29-220 .........v-SHVSAACLMSEALHGVP.NSVKVFKTSAAANVSDASKAREGCQDAVRRAE..DAFSSTPKVE...EAVGRARAALKEAESAENAAKTALSDVEQYAANA............SALANNNVALVDDYLKSVAEDNSAAST..ARRIARDC.NAP.LE-VSSWVLTQAVESGCAV....FMTVI...CNTARARMADLRAEYDQLEAAVRRA.SEARVAARAAES..............
Q38CV3_TRYB2/38-223 .........v-DEIPVLCRVAEQLRGLP.DTISSAVETAAAASSKAFEAKVQAEEAVELAE..SKGLN-----...--VTKAKEAAVRATLAAEAAATAASNVEINAANI............AAVPWSQRRQ-DVGLQELALCDNVDKD..VREAAAKC.TKK.ADNVTAQSLSAALEALENL...yTDVNT...RETLRREDVEFHTELKSLEEHVEEA.VRAQKQAEDAAA..............
Q57U10_TRYB2/29-221 .........v-SHVSAACLFSEALHGIP.FGVKALKASAAANVSDASKAREGCQDAVRRAE..DAFSSTPKVE...EAVGRARAALKEAESAENAAKTALSDVEQYAARA............PLLAAGKTAPIDDYLKSVAEDNSAAST..ARRIARGC.SLP.NRGVNSWVLTQAVESACAI....FMGEI...CRIARTRMVDLRAEYDQLEAAVRRA.SEARVAARAAES..............
F9WEJ8_TRYCI/41-225 .........v-EGVQTMCDVARQLRALE.TASQSAVAAVVSSARDASEAKERAEKAVERAK..SKKRG-----...--VDTATEAAARAAAAAQRAETVVSDARKHAADL............TAASKDAIETTDESLRLLATCEKADEP..IRTAAKKC.TGA.AAEVTSKSLESAFDALAEL....LPD-G...ADDIREHGAVFVKGLKSLEDDVRTA.GEAKNEAEKAE-g.............
Q57Z47_TRYB2/32-225 .........l-EQTKALCEVAKQLRKLP.LLTEERRFEAVGALEESKKAAKEGKKAAKRAE.aGAVGGTSEQQ...QAAKRAREAATVAYEASVRAEAAAMEVKRFARAL............DSFESEYESVFSGLLRGAAEHGG-NET..IKQLAKECaTAV.ADDVTPEALTRAAHNLRGL....YMQDF...AEEYLQEANEAANKLEELQKATAET.VRAADAADDAKS..............
Q38CV1_TRYB2/38-223 .........l-KHIEVLCNLAEQLRGLP.DTVSSAVISVTEASIKASKAKVQAEEAVELAE..SKGLN-----...--VTKAKEAAVRATLAAEAAATAASNVEINAANI............AELPWSQRRR-DAGLQNIEHCKNLDKD..VREAAVKC.TKK.AENVTADSLRAALEGLETL...fSDVYI...LVTLRKEKVEMQEEMQSLEQNAATV.LRVLQKAEDAAA..............
Q38CV6_TRYB2/38-223 ........ag--HVRVVCNLAEQLRGLP.DTVSSALVNAAAASSKAFEAKVQAEEAVELAE..SRGLN-----...--VTKAKEAAVRATLAAEAAATAASNVEINAANV............TSSRLARRNP-NTGFEKIAMCENLDED..VREAAVKC.TKK.AENVTTQSLNEALHRLENL...yTNMSA...LESLRVEHVEIERFFEMLEEHVEEA.VSAQRQAEDAAA..............
Q57X85_TRYB2/29-226 ........de-----AVCELIKQLNGVPwDAVDSMKVHVRRNATVASQSGAIAEMEVRKAY..AAVLR-----...AASSQSAEAIEVVLAAFNKVRTAIVLCNEEIQRVrglwsqfkdaavRVVQC--AEVANGYLKHLVDDAEVSF-..RQHVTDKCnKRE.RKNVTADSLNDAMQRALPF....VKDPT...IRANLTETEKLLRELEGIVGAASEA.RQ----------gaaqqvpmavaa..
F9W3K3_TRYCI/27-147 .........l-DQVNAFCELTKQFRHLP.IAVGQQLDEAIDEEAKAAKARKDSQKAVNRAD..AAAKKSEDAK...KHAQDAKEAAKEAFEAADGAEVHLQAASELATEL............NGLVETHLSRLENILKDAENDGE----..--------.---.-------------------....-----...-------------------------.------------deha..........
F9WE91_TRYCI/41-225 .........v-EEVQTMCDVARQLRALE.TASQSAVGAVVSSARDASEAKERAEKAVERAK..SKKRG-----...--VDAATEAAARAAAAAQRAETVVSDARKHAADL............TAASKDAIETTDESLRLLATCEKADEP..IRTAAKKC.TGA.AAEVTSKSLESAFDALAEL....LPD-G...ADDIREHGAVFVKGLKSLEDDVRTA.GEAKSEAEKAE-g.............
Q57U12_TRYB2/29-220 .........v-SHVSAACLMSEALHGVP.NSVKVFKTSAAANVLDASKAREGCQDAVRRAE..DAFSSTPKVE...EAVGRARAALKEAESAENAAKTALSDVEQYAANA............SALANNNVALVDDYLKSVAEDNSAAST..ARRIARDC.NAP.LE-VSSWVLTQAVESGCAV....FMTVI...CNTARTRMADLRAEYDQLEAAVRRA.SEARVAARAAES..............
F9WH64_TRYCI/1-137 .........n------------------.--------------------------------..------ASAK...ELAERAQAVEAEVTAAADKAQEAYAGVSGFVGNL............TASRDEHLLVLEDVITGAKTSASCSC-..GIRAAKAC.TAA.AEDVTAESLKEAKDTFRQD....IPGDH...YKELSDGAENVSGRLEELRSTAQRV.SASRAAAQAAE-e.............
F9WC09_TRYCI/27-218 .........l-DHVNAFCELTKQFRHLP.IAVGQQLDEAIDEEAKAAKARKDSQKAVNRAD..AAAKKSEDAK...KHAQDAKEAAKEAFEAADGAEVHLQAASELATEL............NGLVETHLSRLEEYLKDAETKGE-DER..AQEAAKEC.TGN.ATNVTSGTLLESKEKLEKA....AGKED...YEELRYDTERAGSLLDDLKGAQLEV.SSLQIKATNAE-e.............
Q38CV9_TRYB2/38-223 ........ag--HVRVVCSLAEQLRGLP.DTISSALVTAAAASSKAFEAKVQAEEAVELAE..SRGLN-----...--VTKAKEAAVRATLAAEAAATAASNVEIDAANV............TSSRLARRNP-NTGFEKVAMCENLDKD..LREAAAKC.TKK.AENVTTQSLSETLHRLENL...yTNMSA...LESLRVEHVEIERFFEMLEEHVEEA.VRAQRQAEEAAA..............
Q38CV7_TRYB2/38-224 .........a-EDVLVLCRVAEQLRGLP.DTVSSALVNAATASSKAFEAKVQAEEAVELAE..SKGLN-----...--VTKAKEAAVRATLAAEAAATAVSYANAHGTKV............GSMTEILWEA-DEELRELVVCKRMDEE..TIKAAAEC.TGT.AEVVTAQSLSEALEALANLh..yGDENV...AETLRRKDVVFHKELKSLEGYVEEA.VHAQKQAEDAAA..............
F9WM65_TRYVY/146-285 statlwsrvn------------------.--------------------------------..----------...--VSVARAAEHESTADGAAAAAVAANASRLAHGV............ARAARELATVVAGLMDEVAASSA-PED..TREAARSC.VGP.AANVSSDSLDEVWNAAAEV....LGGDA...LDFLTARVSGLVGGLRELEAAAVTA.EGAEADGKAA--se............
Q38CU9_TRYB2/38-223 ........av--YVTALCRVAEQLRGLG.GTISSSLLTVTSASSKAFKAKVQAEKAVKLAE..SRGLN-----...--VTKAKEAAVRATLAAEAAATAVSYCITHSTKV............GSIAEMLWEV-DEELHVFSLCGNKDRD..VQDTALKC.TDT.AEGVTAQSLSEALEGLAKL...vFDDNV...ARKLRQEDTVFQREFMWLQQHMEEA.VRAQKQAEDAAA..............
Q38CW1_TRYB2/38-223 .........a-EDVLVLCRVAEQLRGLP.DTVSSALVNAATASSKAFEAKVQAEEAVELAE..SKGLN-----...--VTKAKEAAVRATLAAEAAATAASNVEINAANI............AAVPWLERRQ-NVGWQKLAKCIDLDMD..MREAARVC.RRA.ADNVTAQSLTAALKDLEKV...yTDVST...REALRKETVEFHKELASLEEHVEEA.VRAQKRAEDAAA..............
Q57XI0_TRYB2/27-218 .........l-EQTVTLCNALKQFRGLK.DAVRDLKYWITTESLKISNAKTRSDEYVTLAE..DVLWENRNAT...DPVERAKRVASNVTEAAKKAETASIETEFRAENI............EEIRSNRVAALERMLKEVAGHNSNWR-..VRSAAEKC.KGA.AESVSSDSLNGTLLELFST....LPEGA...SEGLEDDTRESSGELWKLEFVLYNV.VTWRSVA-----lkges.........
F9WC09_TRYCI/239-430 ........vg--QAKAFCKLTEQLRGLL.DTVSRHNVTVTEEVAKTASSKNRSDEAVKQAE..SAAGRNSDAA...PHAKKAKEAGEEVSAAADEAQKAHEDSSRVVQDL............RLLAKDKLSSYDRFLKNVGERAS-GKD..AQNAAKEC.TDS.AVDVKSEVVEKLNAAFEES....TPGKP...FQPVKDLFKKFSDNLKELEGAADVA.SKSRAKAEAAE-k.............
Q38CV8_TRYB2/38-223 ........le--GIPALCGVAEQLRGLP.DTISSALVNVATASSKAFEAKVQAEEAVELAE..SKGLN-----...--VTKAKEAAVRATLAAEAAATAASNVEINAANI............AAVPWSQRRQ-DAGLQKVALCDNVDKD..VREAAAKC.TKK.AENVTAESLRAALEALENL...vTDVKF...QENLRKEDVEFHTELKSLEDHVEEA.VRAQRQAEEAAA..............
Q57U18_TRYB2/29-221 .........v-SHVSAACLFSEALHGIP.FGVKALKALAAANVSDASKAREGCQDAVRRAE..DAFSSTPKVE...EAVGRARAALKEAESAENAAKTALSDVEQYAARA............PLLAAGKTAPVDDYLKSVAEDNSAAST..ARRIARGC.SLP.NRGVNSWVLKKAVEFGCEF....FTGDI...CKILTDGMADLRAEYDQLEAAVRRA.SEARVAARAAES..............
F9WC09_TRYCI/451-642 .........l-KQVNAFCGLAEQFRGLL.NSVKKLEGQATHCATVAAAVKARSTETVKRVV..AAAGKNASAK...ELAERAQAVEAEVTAAADKAQEAYAGVSGFVGNL............TASRDEHLLVLEDVITGAKTSASCSC-..GIRAAKAC.TAA.AEDVTAESLKEAKDTFRQD....IPGDH...YKELSDGAENVSGRLEELRSTAQRV.SASRAAAQAAE-e.............
F9WE93_TRYCI/41-225 .........v-EGVQTMCDVARQLRALE.TASQSAVAAVVSSAREASEAKERAEKAVERAK..SKKRG-----...--VDTATEAAARAAAAAQRAETVVSDARKHAADL............TAASKDAIETTDESLRLLATCEKADEP..IRTAAKKC.TGA.AAEVTSKSLESAFDALAEL....LPD-G...ADDIREHGAVFVKGLKSLEDDVRTA.GEAKSEAEKAE-g.............
F9WP06_TRYVY/468-654 .........g--QARIVCTLMKQLHGVR.RDLIQVMQGVTSNERNASDASQMA---VDAAT..SVAGTKGDDK...RLEEVVAAAIKSREESRRMTEDIQRAKNSIDADV............QGITLYLV-FLKSILLDITKGDN--EY..TKDMIDAC.DKS.SENVTEHSMRAALDEYLRL....KKFVV...VRQIRERVGDVTTDLVKFRQLGEITnLRAQRVASYA--ne............
F9WM12_TRYVY/113-305 .........v-EEVKTMCVLLKQLRGVS.PSVEALVTRANNSLSTISRYKAKEDSALEEAR..RGGSN-----...ETVQKHESRATAVGNAYATAAAAVLSVPDLAANI............TAASTTIINEIVESLDDLEKSEASEE-..VKEAGRPCaAAPaDSGVTSQSLDGVREAIVKK...aAEDDGaelVEEANSVLGHLAAQLRELEAAVATA.AGAEADAKAAS-e.............
F9WE90_TRYCI/41-225 .........v-EEVQTMCDVARQLRALE.TASQSAVAAVVSSAREASEAKERAEKAVERAK..SKKRG-----...--VDAATEAAARAAAAAQRAETVVSDARKHAADL............TAASKDAIETTDESLRLLATCEKADEP..IRTAAKKC.TGA.AAEVTSKSLESAFDALAEL....LPD-G...ADDIREHGAVFVKGLKSLEDDVRTA.GEAKSEAEKAE-g.............
F9WH65_TRYCI/27-218 .........l-DQVNAFCELTKQFRHLP.IAVGQQLDEAIDEEAKAAKARKDSQKAVNRAD..AAAKKSEDAK...KHAQDAKEAAKEAFEAADGAEVHLQAASELATEL............NGLVETHLSRLENILKDAETDGE-DEH..AREAAKEC.TGN.ATNVTSGTLLESKEKLEKA....AGKED...YEELRYDTERAGSLLDDLKGAQLEV.SSLQIKATNAE-e.............
Q38CV5_TRYB2/38-224 .........a-EDVLVLCHVAEQLRGLP.DTVSSALVTAAAASSKAFEAKVQAEEAVELAE..SRGLN-----...--VTKAKEAAVRATLAAEAAATAVSYANAHGTKV............GSMTEILWEA-DEELRELVVCKRMDEE..TIKAAAEC.TGT.AEVVTAQSLSEALEALANLh..yGDENV...AETLRRKDVVFHKELKSLEGYVEEA.VHAQKQAEDAAA..............
Q38CV2_TRYB2/38-223 .........l-EEIRVLCRVAEQLRGLP.ETVSSAVETAAAASSKAFEAKVQAEEAVELAE..SRGLN-----...--VTKAKEAAVRATLAAEAAATAASNVEINAANI............AAVPWLQPIS-DAGLENLSKCEHIDKY..VQEAAAEC.SKK.AEHVTAQSLSAALEGLENL...fTDVST...REALRKETIEFHTELKSLEEHVEEA.VRAQKRAEDAAA..............
F9WE92_TRYCI/41-225 .........v-EGVQTMCDVARQLRALE.TASQSAVAAVVSSAREASEAKERAEKAVERAK..SKKRG-----...--VDTATEAAARAAAAAQRAETVASDARKHAADL............TAASKDAIETTDESLRLLATCEKADEP..IRTAAKKC.TGA.AAEVTSKSLESAFDALAEL....LPD-G...ADDIREHGAVFVKGLKSLEDDVRTA.GEAKSEAEKAE-g.............
F9WH65_TRYCI/451-642 .........l-KQVNAFCGLAEQFRGLL.NSVKKLEGQATHCATVAAAVKARSTETVKRVV..AAAGKNASAK...ELAERAQAVEAEVTAAADKAQEAYAGVSGFVGNL............TASRDEHLLVLEDVITGAKTSASCSC-..GIRAAKAC.TAA.AEDVTAESLKEAKDTFRQD....IPGDH...YKELSDGAENVCGRLEELRSTAQRV.SASRAAAQAAE-e.............
F9WA19_TRYCI/37-229 ........ll--QTTAACGVAEQLRKLP.AAVDAPLLEAERAAERAAKAWNESDRDAKRAEkaAAAAGTAEAQ...GTAKRARDAAEDAYTASVHAEGEKIKAQQEASKL............KDFHEEYESPFNKLLEGTAENGK-NST..IKDVAKNC.-GV.ASDVTPDSLKATAAALNEQ....YSQEF...MREYGQKATQAAESLTELQGAASEG.KKAADDAEEAR-r.............
F9WV46_TRYVY/145-284 statlwsrvn------------------.--------------------------------..----------...--VSVARAAEHESTADGAAAAAVAANASRLAHGV............ARAARELATVVAGLMDEVAASSA-PED..TREAARSC.VGP.AANVSSDSLDEVWNAAAEV....LGGDA...LDFLTARVSGLVGGLRELEAAAVTA.EGAEADGKAA--se............
F9WC08_TRYCI/50-241 .........l-KQVNAFCGLAEQFRGLL.NSVKKLEGQATHCATVAAAVKARSTETVKRVV..AAAGKNASAK...ELAERAQAVEAEVTAAADKAQEAYAVVSGFVGNL............TASRDEHLLVLEDVITGAKTSASCSC-..GIRAAKAC.TAA.AEDVTAESLKEAKDTFRQD....IPGDH...YKELSDGAENVSGRLEELRSTAQRV.SASRAAAQAAE-e.............
F9WVM2_TRYVY/600-786 .........g--QARIICTLMKQLHGVK.RDLIQVMQGVSSNERNASDASQMAEDAATSVA.gTKGDD-KRLEevvAAAIKSREESRRITEDTQRAKNSI-DVDVQGITL............------YLVFLKSILLDITKGDN--EY..TKDMIDAC.DKS.AENVTEHSMRAALDEYLRL....KKIVV...VRQMRERVGDVTTDLVKFRQLGEATnLRAQHVASYAN-e.............
F9WIZ4_TRYCI/34-228 .........v-EAVQSVCELTKIMRGVG.ESTKELQSQAEAHASEASKAKEESESAVGRAE..EANEKSPEAA...DALERAREALSEAEEASEEAALASKEAEKHAENA............TSLATGQQEDLEKFLREIAEDIESDED..IKAVARDC.NDT.NSSVTSEGLDSARRNAKKH....FTSEA...ANTLENITNATVEVFSNLEKEVQRA.KESQDTAEKAR-daa...........
F9WDT3_TRYCI/37-242 ........ll--QTTAACGVAEQLRKLP.AAVDAPLLEAERAADRAAKAWNESDRDAKRAEkaAAAAGTAEAQ...GTAKRARDAAEDAYTASVHAEGEKIKAQQEASKL............KDFHEEYESPFNKLLESAAEDGK-NST..IKDVAKNC.-GV.ASDVTPDSLKATAAALNEQ....YSQEF...MREYGQKATQAAESLTELQGAASEG.KKAADDAEEAR-rlakeaadeiapea
Q38CV4_TRYB2/38-225 .........a-DDVLVLCYLAEQLRGLP.DTISSALVNAAAASSKAFEAKVQAEEAVELAE..SKGLN-----...--VTKAKEAAVRATLAAEAAATAASNVEINAANI............SAFSIDFLESANLLLFEVRDAKDVGED..VRIVAQRC.TGE.ANFVTVASLTNALDNVTSLy..sVYGKG...TASLSMESVALLEELKMLEDGLKKS.QVAVSVAADAA-d.............
F9WQR4_TRYVY/145-284 statlwsrvn------------------.--------------------------------..----------...--VSVARAAEHESTADGAAAAAVAANASRLAHGV............ARAARELATVVAGLMDEVAASSA-PED..TREAARSC.VGP.AANVSSDSLDEVWNAAAEV....LGGDA...LDFLTARVSGLVGGLRELEAAAVTA.EGAEADGKAA--se............
Q57YD8_TRYB2/239-418 .........l-NQTQAVCLMVEQYRGLK.GAVDAFTEQAVSRSAMVSKVEERSQADAKRP-..--GGH-----...--MDQVKRAVAEVAKAVSKAQNVFKKVSRYARNL............KSIRAHYLPLMENTLRKIAGNAA-DEK..AKKAAEVC.GET.AWVVTPKSLDDMRKKLMDN....FP-NL...SERLESDTRVVSHMLEDLNTSTQLI.TIASIA------vrrke.........
Q38CV0_TRYB2/38-224 .........r-DDIQALCRAAEQFRGLS.QTVTSAVETSAAASSKAFEAKVQAEEAVELAE..SRGLN-----...--VTKAKEAAVRATLAAEAAATAASNVEIDAANI............AAVPWSQPSS-DAGLQKLALCENIDKS..LRQLASKC.SKR.AENVTAQSLSEALEGLRKLh..yNDVYV...KEILEREDVEFHKEFMWLQHHLREA.VRAQKQAEDAAA..............
F9WH65_TRYCI/239-430 ........vg--QAKAFCKLTEQLRGLL.DTVSRHNVTVTEEVAKTASSKNRSDEAVKQAE..SAAGRNSDAA...PHAKRAKEAGEEVSAAADEAQKAHEDSSRVVQNL............RLLAKDKLSSYDRFLKNVGERAS-GKD..AQNAAKEC.TDS.AVDVKSEVVEKLNAAFEES....TPGKP...FQPVKDLFKKFSDNLKELEGAADVA.SKSRAKAEAAE-k.............
Q38CW2_TRYB2/38-223 .........a-DVVRILCHVAGQLRGLS.QTVSSAVETAAAASSKAFEAKVQAEEAVELAE..SRGLN-----...--VTKAKEAAVRATHAAEAAALAASNLAFAAANI............AAVPWSQPIS-DSMLHKLALCDHVDEY..VREAAKKC.TKK.AKNVTAQSLNEVLKAFEKL...fSEVNA...LQSLRHNIAEFHKDLKSLEDHVEDI.VRAQKNAEDAAA..............
F9WA18_TRYCI/37-242 ........ll--QTTAACGVAEQLRKLP.AAVDAPLLEAERAADRAAKAWNESDRDAKRAEkaAAAAGTAEAQ...GTAKRARDAAEDAYTASVHAEGEKIKAQQEASKL............KDFHEEYESPFNKLLEGTAENGK-NST..IKDVAKNC.-GV.ASDVTPDSLKATAAALNEQ....YSQEF...MREYGQKATQAAESLTELQGAASEG.KKAADDAEEAR-rlakeaadeiapea
Q57XH8_TRYB2/27-218 .........l-EQTVTLCNALKQFRGLK.DAVRDLKYWITTESLKISNAKTRSDEQLRRVK..EPAQATTKAK...ALEKRARVLAANVTEAVKKAEIVILESDVDAGVL............GTISSAYVPSLEGALKKLGNEGGTVE-..VKGVAKSC.NKT.TKNVTVESLIHALDDMLQY....FPAKS...IKRLKEATRDASNKLHKLEGAAQSL.VEIKINAEYT--ef............
Q57YD8_TRYB2/27-218 .........l-EQTVTLCNALKQFRGLK.DAVRDLKYWITTESLKISNAKTRSDEYVTLAE..DVLWENRNAT...DPVERAKRVASNVTEAAKKAETASIETEFRAENI............EEIRSNRIAALERMLKEVAGHNSNWR-..VRSAAEKC.KGA.AESVSSDSLNGTLLELFST....LPEGA...SEGLEDDTRESSGELWKLEFVLYNV.VTWRSVA-----lkges.........
#=GC seq_cons .........l.pplpshCplucQLRGL..ssVpshhhpusssuscAucAKtpu-cAVctA-..ututs..........lp+A+-AuscAstAuptApsAhssspthAusl............suhsppthpsh-phLcplupssshsc...s+cAA+pC.sss.ApsVTupSLppAhcsltph....hssps...hcplcpcssphtppLcpLEsssppu.scAptpAcsAt...............
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