#=GF ID   Gag_spuma_N
#=GF AC   PF03276.18
#=GF DE   Spumavirus gag protein, N-terminal
#=GF PI   Gag_spuma;
#=GF AU   Mifsud W;0000-0002-9805-6461
#=GF SE   Pfam-B_1878 (release 6.5)
#=GF GA   25.00 25.00;
#=GF TC   25.80 58.60;
#=GF NC   23.50 21.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Group-specific_antigen
#=GF CL   CL0148
#=GF RN   [1]
#=GF RM   9261397
#=GF RT   Characterization of the genome of feline foamy virus and its
#=GF RT   proteins shows distinct features different from those of primate
#=GF RT   spumaviruses. 
#=GF RA   Winkler I, Bodem J, Haas L, Zemba M, Delius H, Flower R, Flugel
#=GF RA   RM, Lochelt M; 
#=GF RL   J Virol 1997;71:6727-6741.
#=GF RN   [2]
#=GF RM   27829070
#=GF RT   Structure of a Spumaretrovirus Gag Central Domain Reveals an
#=GF RT   Ancient Retroviral Capsid.
#=GF RA   Ball NJ, Nicastro G, Dutta M, Pollard DJ, Goldstone DC,
#=GF RA   Sanz-Ramos M, Ramos A, Mullers E, Stirnnagel K, Stanke N,
#=GF RA   Lindemann D, Stoye JP, Taylor WR, Rosenthal PB, Taylor IA;
#=GF RL   PLoS Pathog. 2016;12:e1005981.
#=GF DR   INTERPRO; IPR004957;
#=GF DR   MEROPS; A9;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This is the conserved N-terminal domain of the Gag polyprotein
#=GF CC   from Foamyviruses (FVs) or Spuma-retroviruses. Gag is the major
#=GF CC   structural protein required for genome packaging virion
#=GF CC   assembly, trafficking and egress. This region corresponds to the
#=GF CC   Env-binding domain containing the cytoplasmic targeting and
#=GF CC   retention sequence (CTRS) [1,2].
#=GF SQ   15
#=GS A8HC77_9RETR/10-151      AC A8HC77.1
#=GS GAG_SFVCP/12-153         AC Q87039.1
#=GS GAG_FOAMV/12-153         AC P14349.2
#=GS O41893_9RETR/14-147      AC O41893.1
#=GS D5JWV0_9RETR/13-155      AC D5JWV0.1
#=GS A0A077JHG2_9RETR/8-149   AC A0A077JHG2.1
#=GS Q7SIS7_9RETR/8-149       AC Q7SIS7.1
#=GS L7RYH3_9RETR/5-145       AC L7RYH3.1
#=GS Q9J4C8_9RETR/21-148      AC Q9J4C8.1
#=GS GAG_SFV3L/6-147          AC P27400.1
#=GS A0A0G3Y5U1_9RETR/13-155  AC A0A0G3Y5U1.1
#=GS A0A088F783_9RETR/42-183  AC A0A088F783.1
#=GS GAG_FFV/5-146            AC O56860.1
#=GS D5JWU5_9RETR/6-149       AC D5JWU5.1
#=GS K7Z2A6_9RETR/6-147       AC K7Z2A6.1
A8HC77_9RETR/10-151                 .................IDIGHLTILLRENGLPTNPPHGTEYAVRMTEGWWGDYARFTVIRVAFQD.NQGNPLPRPEWEYI.NRDV.RPLND..SIIGCTFRQAQQAFNNIDLARTPSRYGPLSNGLFLITDPEWLTFNPLSAVEIADL..DDQ.EIRDFLAHATI-v.....................
GAG_SFVCP/12-153                    .................LDVEALVVILRDRNIGRNPLHGEIIGLRLTEGWWGQLERFQMVRLILQD.EDNEPLQRPRHEII.PRAV.NPHTM..FVLSGPLAELQLAFQDLDLPEGPLRFGPLANGHYVEGDPYSRSYRPVTMAETAQM..TRD.ELEDTLNTQSEI......................
GAG_FOAMV/12-153                    .................LDVEALVVILRDRNIPRNPLHGEVIGLRLTEGWWGQIERFQMVRLILQD.DDNEPLQRPRYEVI.QRAV.NPHTM..FMISGPLAELQLAFQDLDLPEGPLRFGPLANGHYVQGDPYSSSYRPVTMAETAQM..TRD.ELEDVLNTQSEI......................
O41893_9RETR/14-147                 .........ylpaprvl-------------------QHNDIIICRATSGPWGIGDRYNLIRIHLQD.PAGQPLPIPQWEPIpNRTA.NPRTQpyPVVSAPMATLENILNNFHIPHGVSRYGPLEGGDYQPGEQYSQGFCPVTQAEIALL..NGQ.HLEEEITILRE-i.....................
D5JWV0_9RETR/13-155                 .................LNVVELTHLLRENGLPGNPRNGQTYAIAMTEGWWGDHPRYRIIRVVFQD.TSGNPLSQPQWMDE.DRQM.NPLQD..PVVGCTFNQASRVFDQIDIGEGPSRFGPLADGMFLITDNAWMDFVPLSAMEITDI..NNErTLRDHLTFCCT-l.....................
A0A077JHG2_9RETR/8-149              .................LDVQALTDLFNNLGINRDPRHREVIALRMTGGWWGPATRYNLVTILLQD.DQGQPLQQPRWRAE.GRAA.NPAVM..FTLEAPWQDLRMAFDNIDLADDTLRFGPLANGNYIPGDEYSLEFIPPAMQEIAQM..QRD.ELENVLDIVGQI......................
Q7SIS7_9RETR/8-149                  .................LDVQELLNLFQDNGVTRNPRHLETIGLRMLGGWWGEQERYQSARIILQD.DDGEPLQVPRWEEV.LRPV.NPLAH..FVISAPWDQLRRAFHDLDVGNGALRFGPLANGNYIPEDPYSTSYRPVNPQEMAQM..QRD.ELEEVLEVQGEI......................
L7RYH3_9RETR/5-145                  .............lnpl----QLQQLYINNGLQPNPGHGDVIAVRFTGGPWGPGDRWARVAIRLQD.NTGQPLQVPGYDLE.PGII.NLRED..ILIAGPYNLIRTAFLDLEPARGPERHGPFGDGRLQPGDGLSEGFQPITDEEMQ--..---.------------tevgtigaarneirll......
Q9J4C8_9RETR/21-148                 ..............ila--------------------DNDIINIRFTSGQWGIGDRWLQVRLRLVDpNTGQPLAQPEYEDT.GLPA.EN-RG..IVVAVSHNAARNIFNNVQPAGGPNRHGPLHDGQFQVGDDPSEHFVPIEENL----..---.------------ipqeivnlgaarrevrllremc
GAG_SFV3L/6-147                     .................LNVQELLNLFQNLGIPRQPNHREVIGLRMLGGWWGPGTRYILVSIFLQD.DSGQPLQQPRWRPE.GRPV.NPLVH..NTIEAPWGELRQAFEDLDVAEGTLRFGPLANGNWIPGDEYSMEFQPPLAQEIAQM..QRD.ELEEILDITGQI......................
A0A0G3Y5U1_9RETR/13-155             .................LNVVELTYLLRENGLPGNPRDGQTYAVAMTEGWWGDHSRYRVVRVVFQD.TSGNPLPQPQWMDE.DRHM.NPLQD..PVIGCTFNQALRAFDQIDLGEGPSRFGPLADGMFLISDNAWMDFVPLSAMEITDL..DNErALREHLTYCCT-l.....................
A0A088F783_9RETR/42-183             ldvlllqqeyhlidpnl-----------------QVQHLDTLLVRITGGNWGPGDRFARIEVLLRD.TLG-PLQQPRYRYA.AMQQaDLRND..IILHLNYQDAIIIFDMIIPSEGVHRHGPMFDGLWIHGDDYSMNFQPITAHELYLL..PQQ.VLTEEVELLTEV......................
GAG_FFV/5-146                       .............lnpl----QLQQLYINNGLQPNPGHGDIIAVRFTGGPWGPGDRWARVTIRLQD.NTGQPLQVPGYDLE.PGII.NLRED..ILIAGPYNLIRTAFLDLEPARGPERHGPFGDGRLQPGDGLSEGFQPITDEEIQ--..---.------------aevgtigaarneirllr.....
D5JWU5_9RETR/6-149                  .................LDIARLTVLLQENSLSGNPPHLTHYVLRMTEGWWGPFPRYTRVRIILQD.ESGNPLSQPRWELV.DRMF.NPLRD..PILETTLDEMDRVFDGINLSPGTERYGPLCDGNFLYTDDAWNDFNPMSALEVADVelTPA.LYREHLNFLSRV......................
K7Z2A6_9RETR/6-147                  .................LNVQELLNLFQNLGIPGQPNHREVFGLRMTGGWWGLGTRYNLVSIFIQD.DSGQPLQQPRWRAE.NRPV.NPMVH..NTIEAPWGDLRLAFEDLDVAEGALRFGPLANGNWIPGDQYSMEFQAPLVQEIAMM..QQA.ELEEILDVVGQI......................
#=GC seq_cons                       .................Lsl.pLh.LhpppGlstNPtHs-lIulRhTuGWWGstsRaphVRlhLQD.ssGpPLQpPcW-ht.sRss.NPhsc...lluuPasplcpAFpslDlucGspRaGPLusGpal.GDshShsFpPlostElAph..ppp.pLc-hLshhsp.......................
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