#=GF ID   HA1
#=GF AC   PF18239.5
#=GF DE   Hemagglutinin I
#=GF AU   Smart A;0000-0002-6965-5633
#=GF SE   ECOD:EUF03804
#=GF GA   26.30 26.30;
#=GF TC   27.90 30.50;
#=GF NC   25.90 25.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF CL   CL0004
#=GF RN   [1]
#=GF RM   21094650
#=GF RT   The Structure of Physarum polycephalum hemagglutinin I suggests
#=GF RT   a minimal carbohydrate recognition domain of legume lectin fold.
#=GF RA   Kouno T, Watanabe N, Sakai N, Nakamura T, Nabeshima Y, Morita M,
#=GF RA   Mizuguchi M, Aizawa T, Demura M, Imanaka T, Tanaka I, Kawano K;
#=GF RL   J Mol Biol. 2011;405:560-569.
#=GF DR   INTERPRO; IPR040862;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This domain is hemagglutinin I (HA1) present in Physarum
#=GF CC   polycephalum. Although the physiological function of the
#=GF CC   secreted HA1 remains to be established, HA1 recognizes cell wall
#=GF CC   polysaccharides of E. coli. The beta-sandwich fold of HA1,
#=GF CC   composed of two up and down beta-sheets, is conserved among
#=GF CC   other legume lectin-like proteins. The up and down beta-sheet
#=GF CC   region is a minimal carbohydrate recognition domain [1].
#=GF SQ   7
#=GS A0A0C9Y247_9AGAR/3-92  AC A0A0C9Y247.1
#=GS A0A0C9SNM9_PAXIN/3-90  AC A0A0C9SNM9.1
#=GS A0A0C9SNN6_PAXIN/3-90  AC A0A0C9SNN6.1
#=GS A0A0C9ST52_PAXIN/3-90  AC A0A0C9ST52.1
#=GS A0A0C9WJT4_9AGAR/3-92  AC A0A0C9WJT4.1
#=GS B0CWZ4_LACBS/3-92      AC B0CWZ4.1
#=GS B0CWZ6_LACBS/3-92      AC B0CWZ6.1
A0A0C9Y247_9AGAR/3-92             WGISFQNNTNLSVTLTPNGNVGSADRFIQVAGYHSIIIQEVGNRVRRTGTTWAVVVYDGFH.NFELGYEGGPTFNFVISRDPKLGIVYTV-n.............
A0A0C9SNM9_PAXIN/3-90             WAVFLNNTTVLSTSIPPTAEYRGITRYLFIQGRDLPIIL--TDEASELPQSWAVGVNDGVNpHFQLGYEGGGKIDI---------------tlrsvndvlqytas
A0A0C9SNN6_PAXIN/3-90             WAVFLNNTTVLSTSIPPTAEYRGITRYLFIQGRDLPIIL--TDEASELPQSWAVGVNDGVNpHFQLGYEGGGKIDI---------------tlrsvndvlqytas
A0A0C9ST52_PAXIN/3-90             WAVFLNNTTVLSTSIPPTAEYRGITRYLFIQGRDLPVIL--TDEKSKLPQSWAVGVNDGVNpHFQLGYEGGGKIDI---------------tlrsvndvlqytas
A0A0C9WJT4_9AGAR/3-92             WGISFQNTTNLSVSLTPNGNTGSVDRFIQVDGYHSIVIQEAGDRVRRTSTTWAVVVYDGFH.NFELGYEGGPTFNFVIARDPTHGIVYSVS..............
B0CWZ4_LACBS/3-92                 WGVSFQNTTNLSVSLTPNGNVGSADRFIQVDGYHSIVIQEVGDRVRRTSTTWAVVVYDGFH.NIELGYEGGPTFNFVISRDPTRGIVYSE-s.............
B0CWZ6_LACBS/3-92                 WGISFQNNTNLSVTLTPNGNVGSADRFIQVAGYHSIIIQEVGNRVRRTGTTWAVVVYDGFH.NFELGYEGGPTFNFVISRDPTLGIVYTV-n.............
#=GC seq_cons                     Wul.hpNTTsLSsSlsPsuphtuhsRal.lpGhc..lI...sDcsp+hspoWAVsV.DGhp.pFpLGYEGGsphsh...............s.............
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