#=GF ID HEPN_RnaseLS
#=GF AC PF18869.5
#=GF DE RnaseLS-like HEPN
#=GF AU Iyer LM;0000-0002-4844-2022
#=GF AU Aravind L;0000-0003-0771-253X
#=GF AU Burroughs AM;0000-0002-2229-8771
#=GF AU El-Gebali S;0000-0003-1378-5495
#=GF SE Iyer LM
#=GF GA 29.00 29.00;
#=GF TC 29.10 30.60;
#=GF NC 28.20 28.50;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF CL CL0291
#=GF RN [1]
#=GF RM 23768067
#=GF RT Comprehensive analysis of the HEPN superfamily: identification
#=GF RT of novel roles in intra-genomic conflicts, defense,
#=GF RT pathogenesis and RNA processing.
#=GF RA Anantharaman V, Makarova KS, Burroughs AM, Koonin EV, Aravind L;
#=GF RL Biol Direct. 2013;8:15.
#=GF DR INTERPRO; IPR040975;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC RnaseLS-like HEPN [1].
#=GF SQ 3
#=GS A0A848M307_PAELE/4-103 AC A0A848M307.1
#=GS A0A1B6BF20_9FIRM/224-349 AC A0A1B6BF20.1
#=GS A0A3E2NW29_9SPHI/205-328 AC A0A3E2NW29.1
A0A848M307_PAELE/4-103 ............knilis-------------------------------FFPVLRALEGYIKLLFLT.KG.IR.I......A....K..R.....NG....FDEH.....IF.CH..D.Q.KYF.....LR.PDK.RALI.N..C.E.AtCA.........A..IERSFNYFNEHRNGLFHAD...G.....IDANIRLVETKQEA--dr.....
A0A1B6BF20_9FIRM/224-349 .......itpklknsflq--------------AIYNLNIDGDMFDYTFMTFPAYRGLEGHLRYLFKT.HG.IN.A......D....K..F.....IV....KEFD.....YD.EK..T.D.FHI.....LK.TKY.YPSF.DhsT.N.K.IA.........Y..INKVYSKYRAVRNNIFHWDspiG.....TFDNTVIFNDIDI---akt....
A0A3E2NW29_9SPHI/205-328 ..................HLFLGDTLTAIISPAIVLKKIQATLADYSYIVYPALRGLEGFIKKMFKD.CG.IV.I......G....D..N.....FG....GYVS.....YD.DA..T.D.TAT.....LS.ADH.HHLF.N..A.N.Q.IV.........A..IQEAYKYYKKNRHGLFHVD...G.....TIDSTRIIDDQEDAQD.......
#=GC seq_cons ............KN.hlp..............AIh.hpIpushhDYoahsFPALRGLEGaIKhLFKT.+G.Is.I......u....K..p.....hG....t-hc.....YD.-+..T.D.pah.....L+.sD+.+sLF.N..s.N.p.IA.........A..Ip+uYsYY+csRNGLFHsD...G.....ThDNTRIl-Dp--A..s+.....
//
