#=GF ID HP0268
#=GF AC PF18618.5
#=GF DE HP0268
#=GF AU El-Gebali S;0000-0003-1378-5495
#=GF SE ECOD:EUF08406
#=GF GA 25.00 25.00;
#=GF TC 67.80 67.60;
#=GF NC 23.70 20.30;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP Domain
#=GF RN [1]
#=GF RM 25916841
#=GF RT Structure-based functional identification of Helicobacter pylori
#=GF RT HP0268 as a nuclease with both DNA nicking and RNase activities.
#=GF RA Lee KY, Lee KY, Kim JH, Lee IG, Lee SH, Sim DW, Won HS, Lee BJ;
#=GF RL Nucleic Acids Res. 2015;43:5194-5207.
#=GF DR INTERPRO; IPR040748;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC HP0268 is a small, characterized protein that is conserved in H.
#=GF CC pylori strains and consists of 80 amino acid residues with a
#=GF CC molecular weight of approximately 9.5 kDa. HP0268 has nicking
#=GF CC endonuclease and RNase activities, both of which are specific
#=GF CC for a single-strand of nucleotides. It is structurally similar
#=GF CC to small MutS-related (SMR) domains, that can be categorized
#=GF CC roughly into three subfamilies according to their arrangement in
#=GF CC the domain architecture.HP0268 falls into subfamily 3 that is
#=GF CC found as stand-alone type proteins. It is proposed that HP0268
#=GF CC has become an evolutionary intermediate between RNases and
#=GF CC nicking endonucleases during H. pylori adaptation to the
#=GF CC extremely acidic environment of the stomach [1].
#=GF SQ 86
#=GS A0A6L5WF70_9PROT/1-80 AC A0A6L5WF70.1
#=GS D5V755_ARCNC/1-80 AC D5V755.1
#=GS A0A1S6U8F4_9PROT/1-80 AC A0A1S6U8F4.1
#=GS O25047_HELPY/1-80 AC O25047.1
#=GS J0LDF2_9PROT/1-81 AC J0LDF2.1
#=GS A0A128EDU2_9PROT/1-80 AC A0A128EDU2.1
#=GS T1CN70_9HELI/1-82 AC T1CN70.1
#=GS A0A2P8R1A6_9PROT/1-80 AC A0A2P8R1A6.1
#=GS A0A076FAG1_9PROT/1-80 AC A0A076FAG1.1
#=GS A0A7S7LZE8_9PROT/1-80 AC A0A7S7LZE8.1
#=GS C5ZVX2_9HELI/1-80 AC C5ZVX2.1
#=GS D1AZJ8_SULD5/1-80 AC D1AZJ8.1
#=GS I2K5Y4_9PROT/1-78 AC I2K5Y4.1
#=GS A0A222MXA2_9PROT/1-80 AC A0A222MXA2.1
#=GS A0A099UC78_9HELI/1-80 AC A0A099UC78.1
#=GS F8KRG3_HELBC/1-81 AC F8KRG3.1
#=GS A0A381DI93_9PROT/1-80 AC A0A381DI93.1
#=GS A0A3D8J818_9HELI/1-78 AC A0A3D8J818.1
#=GS E0UPC4_SULAO/1-80 AC E0UPC4.1
#=GS A0A099V6Q3_9HELI/1-84 AC A0A099V6Q3.1
#=GS A0A4Q0XZI3_9PROT/1-80 AC A0A4Q0XZI3.1
#=GS A0A7H9CII3_9PROT/1-81 AC A0A7H9CII3.1
#=GS A0A091AH50_9PROT/1-80 AC A0A091AH50.1
#=GS A0A3D8I6X9_9HELI/1-84 AC A0A3D8I6X9.1
#=GS A6QCD1_SULNB/1-78 AC A6QCD1.1
#=GS A0A2D3W546_9PROT/1-80 AC A0A2D3W546.1
#=GS A7I0Q4_CAMHC/1-80 AC A7I0Q4.1
#=GS A0A2D3WDC0_9PROT/1-80 AC A0A2D3WDC0.1
#=GS B6BIG3_SULGG/1-80 AC B6BIG3.1
#=GS A0A5P8P4G3_9PROT/1-76 AC A0A5P8P4G3.1
#=GS Q7MR24_WOLSU/1-80 AC Q7MR24.1
#=GS A0A1I5P9B2_9PROT/1-80 AC A0A1I5P9B2.1
#=GS A0A6G5R273_9PROT/1-80 AC A0A6G5R273.1
#=GS H5VEW1_HELBI/1-81 AC H5VEW1.1
#=GS A0A347VN61_9HELI/4-86 AC A0A347VN61.1
#=GS C6RIR2_9PROT/1-80 AC C6RIR2.1
#=GS A0A3D8HPF4_9HELI/1-83 AC A0A3D8HPF4.1
#=GS A0A345J0F7_9PROT/1-80 AC A0A345J0F7.1
#=GS A0A8E7L2E7_9CAUD/1-80 AC A0A8E7L2E7.1
#=GS A0A1B8J8P6_9HELI/1-87 AC A0A1B8J8P6.1
#=GS S3YPR2_9PROT/1-80 AC S3YPR2.1
#=GS A0A3G9GTS2_9PROT/1-80 AC A0A3G9GTS2.1
#=GS A0A1B1U668_9HELI/1-79 AC A0A1B1U668.1
#=GS E4TYI5_SULKY/1-80 AC E4TYI5.1
#=GS A0A1P8KQ01_9PROT/1-80 AC A0A1P8KQ01.1
#=GS A0A2D3W1Q6_9PROT/1-80 AC A0A2D3W1Q6.1
#=GS A0A329ZTF8_9HELI/1-80 AC A0A329ZTF8.1
#=GS V8CKG6_9HELI/1-82 AC V8CKG6.1
#=GS A0A2D3WAD2_9PROT/1-80 AC A0A2D3WAD2.1
#=GS A0A2D3WFP6_9PROT/1-78 AC A0A2D3WFP6.1
#=GS A0A2W6MXK7_9HELI/1-80 AC A0A2W6MXK7.1
#=GS A0A2A2GU85_9HELI/1-82 AC A0A2A2GU85.1
#=GS Q7VGP7_HELHP/1-86 AC Q7VGP7.1
#=GS A0A4Q0XQ92_9PROT/1-80 AC A0A4Q0XQ92.1
#=GS A0A3D8IG72_9HELI/1-80 AC A0A3D8IG72.1
#=GS A0A7L8V4Y5_9PROT/1-76 AC A0A7L8V4Y5.1
#=GS C8PFL0_9PROT/1-80 AC C8PFL0.1
#=GS A8ERE8_ALIB4/1-80 AC A8ERE8.1
#=GS A0A3D8IZ33_9HELI/1-79 AC A0A3D8IZ33.1
#=GS E7G5A2_9HELI/1-80 AC E7G5A2.1
#=GS A0A363CZ36_9PROT/1-80 AC A0A363CZ36.1
#=GS A0A345J836_9PROT/1-80 AC A0A345J836.1
#=GS A7GZE0_CAMC5/1-80 AC A7GZE0.1
#=GS A0A329ZF30_9HELI/1-83 AC A0A329ZF30.1
#=GS A0A3D8HX75_9HELI/1-80 AC A0A3D8HX75.1
#=GS A0A5P8P2M1_9PROT/1-80 AC A0A5P8P2M1.1
#=GS A6Q532_NITSB/1-80 AC A6Q532.1
#=GS A0A268U5L9_9HELI/1-81 AC A0A268U5L9.1
#=GS B9L7T4_NAUPA/1-76 AC B9L7T4.1
#=GS A0A7M1AVJ8_9PROT/1-80 AC A0A7M1AVJ8.1
#=GS A0A268T8T2_9HELI/1-80 AC A0A268T8T2.1
#=GS Q30PR0_SULDN/1-80 AC Q30PR0.1
#=GS A0A3D8ILJ8_9HELI/4-87 AC A0A3D8ILJ8.1
#=GS A0A6M0L1Z1_9PROT/1-78 AC A0A6M0L1Z1.1
#=GS A0A6G5QHV6_9PROT/1-80 AC A0A6G5QHV6.1
#=GS I7HE50_9HELI/1-83 AC I7HE50.1
#=GS Q0PB54_CAMJE/9-88 AC Q0PB54.1
#=GS T0JSB7_9PROT/1-80 AC T0JSB7.1
#=GS A0A7M1LGH3_9PROT/1-80 AC A0A7M1LGH3.1
#=GS E6WZ14_NITSE/1-78 AC E6WZ14.1
#=GS V8CA71_9HELI/1-90 AC V8CA71.1
#=GS D3UG84_HELM1/1-78 AC D3UG84.1
#=GS A0A4U7BGZ9_9PROT/1-80 AC A0A4U7BGZ9.1
#=GS A0A099TYG1_9HELI/1-84 AC A0A099TYG1.1
#=GS A0A1X9STV5_9PROT/1-80 AC A0A1X9STV5.1
#=GS A0A5C8L5Y4_9PROT/1-80 AC A0A5C8L5Y4.1
A0A6L5WF70_9PROT/1-80 .MELKLARKEP....DKSGG........TITLEKIEQEIKKAG.....QKIFYFDRENQHKDLIALIEHFESN.GMSAYLRTVKYGLDDNEYMYEVHIL.
D5V755_ARCNC/1-80 .MELLFARNEL....NEKPK........KVKIDKIVEELKELG.....EKIFYFDKDNSHKDMMALVDGLEGE.GFNVYFREVKYGLAEDEYMYEVHAL.
A0A1S6U8F4_9PROT/1-80 .MELKLARSEL....SSKPK........TISLDKIEAAVSKEG.....QKIFYFDKDNSHKQLIELVEFFEEK.GLSVYHRVVKYGLDDKDYMYEVHIL.
O25047_HELPY/1-80 .MKLVLAKNTR....KSDAK........SVELEDLYHEFSEDK.....RSIFYFAPTNAHKDMLKAVDFFKEK.GHTAYLDEVRVSTDEKDFLYELHII.
J0LDF2_9PROT/1-81 .MEFKLARESL....DSQPE........VVNLDYIEKQAEKED.....ETIIYLDRTNSQKVLNQLEKHFDKNfEKNVYRREVKFGLDENDYLYEVHIL.
A0A128EDU2_9PROT/1-80 .MELKLARTEL....DKAPK........NIAIEKIEEDLEKSG.....QKIYYFDRENSHKDLIALIEFFEKK.GLSVYHRTVKYGLDDNEYMYEVHIL.
T1CN70_9HELI/1-82 .MELKLATMDI....GQTPK........KITLDGLYEQISSTNk...dSIFYYFDRENSHKELQKAKTFLESK.GKKVYIDEVHYGLDPKDFIYEFHIV.
A0A2P8R1A6_9PROT/1-80 .MELKIARIEL....DEAPK........KITLDKIEEEIKKVG.....QKIYYFDKENSHKDLIALIEYFEEE.GFSAYLRTVKYGLDENEYMYEVHIL.
A0A076FAG1_9PROT/1-80 .MELKLARTEL....DNKPK........TISIDKIEAAVSKDG.....GKIFYFDKDNSHKELIALVEYFEQK.GLSVYHRTVKYGLDENDYMYEVHIL.
A0A7S7LZE8_9PROT/1-80 .MDLKFARTDV....ASKPK........KVDLAKLEASVEKDD.....SVIFYFDKENSHKDLLELQDYFEEK.GKSFYMSEVKYGLADSEYMYQVHII.
C5ZVX2_9HELI/1-80 .MDIKLVREHI....NEKPQ........KVTIKKLEEMLETKK.....MDIFYCDKENSHKDMMALMDYFEKK.GKHVYFREVKYGLDEGDYMYEFHIL.
D1AZJ8_SULD5/1-80 .MEIKLARNEI....NGKPK........TITLEKITEIIEKEG.....QKIFYFDKENSHKDLVALVETFETK.GFSVYLRDIKYGLGEGDYMYEVHIL.
I2K5Y4_9PROT/1-78 .MKLKLARTTL....KAKPK........TIELQKIEDELAN--.....RSIFYFDKDNSHKELKELIEYFEEK.GFSVYMREVKYGLDDNEYIYEVHII.
A0A222MXA2_9PROT/1-80 .MDVKLARTLL....DEKAK........SVSLKKLEELLEQEN.....QSFFYLDRENSKKTLTSLAQHFEKK.GLSVYYREVRYGLDSGDYMYEVHI-f
A0A099UC78_9HELI/1-80 .MDIKLAREHI....NQKPV........KIAIKKLEEMLEAKK.....TDIFYCDKENSHKEITNLIEYFAKK.GKHAYCREVRYGLDEGDYMYEIHIM.
F8KRG3_HELBC/1-81 .MELRLARSDR...kQSKSH........TISLEDLHQKYLKHK.....EHIFYFAPSNTHKDMLGAVGFFAKK.GCKAYLSEVQISTDDKDFIYQLHII.
A0A381DI93_9PROT/1-80 .MELKLARSEI....NGKPK........VISITKIEEDIQKVG.....QKIFYLDKENSHKDMLAFVEYFEKK.GFSVYHRTVKYGLSENDYMYEVHIL.
A0A3D8J818_9HELI/1-78 .MELKLALTNK....DSQPQ........NISLDEMMEQAVG--.....EKFFYLDRENKEKDLQKVMKAFLDK.KRSAKLNKISFGLDEKEFIFELHII.
E0UPC4_SULAO/1-80 .MDLKFARTDL....DAKPK........KADLAKLDAEVAKND.....SIIFYFDRENSHKDLLELQDHYEAM.GKSFYMSEVKYGLSDNDYMYQVHIM.
A0A099V6Q3_9HELI/1-84 .MELKLAKESLk..aDIKAN........TITFEAMAKKVEESGs...kGAIFYLDRENAEKDLKKLESFFKGK.NHHTLIRELRYSMDTKDYIYEVHIL.
A0A4Q0XZI3_9PROT/1-80 .MELLFARNEL....SEKPK........KVQLDKIKEELQKDG.....EKIFYFDRDNSHKDMMSLVDSLEDE.GYNVYFREVKYGLADDEYMYEVHAL.
A0A7H9CII3_9PROT/1-81 .MELRLARDEI....NKKPS.......hTISLEKIENELQKQG.....EKIYYFDKENTHKQLISMVEHFEKK.GFSVYHRIVKYGLNESQYCYEVHIL.
A0A091AH50_9PROT/1-80 .MELKIARSEH....DAKPK........KIDLKKITEMVEKTN.....SLMLYFDRENSHKDLLALQDHFEGE.GKSFYMREVRYGLSANEYMYEVHIL.
A0A3D8I6X9_9HELI/1-84 .MELKLAKDSFk..sDSPQE........SITLEKMAEVVNNNEk...rGAIFYLDRENPEKNLKKLESFFKSK.NRSTIVRELKISMDEKDYIYEVHIL.
A6QCD1_SULNB/1-78 .MKLKLARTTL....KAKPK........TIELKKLEEELAN--.....RSIFYFDKDNSHKELKELIEYFEEK.GYSVYMREVKYGLDDNEFIYEVHII.
A0A2D3W546_9PROT/1-80 .MEIKLARNEI....NGKPK........TITLEKVAEIIEKEG.....QKIFYFDKENSHKDLVALVEHFEAK.GLSVYLRDIRYGLGESDYMYEVHIL.
A7I0Q4_CAMHC/1-80 .MNLKLARTEI....NAKPA........EISLEKLEEEVKKNG.....QNFFYFDRENSHKDLILLIEAFEKK.GYSVYHRTVKIGLGENEYMYEVHIL.
A0A2D3WDC0_9PROT/1-80 .MELKLARNEI....NGKPK........AVQLEKIEEIIAKEN.....QKIFYFDKENSHKDLVALVDYFEEK.DFSVYLREVKYGLGEEDYMYEVHIL.
B6BIG3_SULGG/1-80 .MDLKFARTDI....DTKPK........KADLEKIEASVEKEG.....SVIFYFDRENSHKDLLELQDYFEEK.GKSFYLSEVKFGLSDNEYMYQVHII.
A0A5P8P4G3_9PROT/1-76 m-----CKNRV....RCKPK........KADIKKIEESVEKNG.....SVIFYFDRENSHKDLLELQDYFEEK.GKGFYMNEVKFGLSDNEYMYQVHII.
Q7MR24_WOLSU/1-80 .MDIKLARTEI....EGKPT........KISVEKLEERLEAKG.....QKIFYFDKDNSHKDMMNLIDYFESK.GRSVYFREIRYGLDESDYMYEVHII.
A0A1I5P9B2_9PROT/1-80 .MELKAVRTEL....NAKPK........TISLEKIEKEIEKEG.....QKIFYFDRENSHKDLMEMVEYFESK.GLSVYFKEVRYGLDENDYLYEAHIL.
A0A6G5R273_9PROT/1-80 .MELKLARNEI....DAKPK........TISIDKIEAAVNKDG.....QKIFYFDKENSHKQLIALIEYFEEK.GLSVYHRTVKYGLDENDYMYEVHIL.
H5VEW1_HELBI/1-81 .MELRLARSDR...kQSKSH........TISLEDLHQKYLKHK.....EHIFYFAPSNTHKDMLGAVDFFAKK.GCKAYLSEVQISTDDKDFIYQLHII.
A0A347VN61_9HELI/4-86 k-EIKLAKESL...kDSKSE........SISLAKMGEIVDKGGk...nGAFFYLSKDNQEKDLKKLESFFKAR.KRNIMLRELRYNMDTKDYIYELHVL.
C6RIR2_9PROT/1-80 .MELKLARTQL....DAKPK........TISLEKIEAAFAKDP.....QQIFYFDRENSHKQLIALVEFFEEK.GLSVYHRTVKYGLDENDYMYEVHIL.
A0A3D8HPF4_9HELI/1-83 .MELKIARTDL....TSKKKv.....eaKISLDEITQKVREQN.....EHAFYFDGTNSHKDMQKAKANLEKS.GFRVQLNEVRYGLDENNYIYELYV-v
A0A345J0F7_9PROT/1-80 .MELLFARNEL....TEKPK........KVQLDKIKEELTKSG.....EKIFYFDRDNSHKDMMSLVDALEDE.GYNVYFREVKYGLADEEYMYEVHAL.
A0A8E7L2E7_9CAUD/1-80 .MELKLARTLI....NEKPK........NISLEKIEEAIEKEG.....QKFFYFDKDNTHKQLIALVNHFEKK.GVSIYHRTVKYGLDDNDFMYEVHIL.
A0A1B8J8P6_9HELI/1-87 .MELKLAPMDLg..qTAQKQ........TIKVESLLEKPDTKSkapssIQIVYFDKTNSNKDLQKAKALLESK.GKVVYMNEVRYGLDAKDFIYEFRII.
S3YPR2_9PROT/1-80 .MELKIARSEL....SKAPN........NISLSDIEKEVAKTG.....QRIFYFDRENQHKDLIALIEHFKKK.NMSAYLRTVKYGLDENEFMYEVHIL.
A0A3G9GTS2_9PROT/1-80 .MELKAARTEL....NAKPK........AITVEKIEKELEKEG.....QKIFYFDRENSHKDLMEMVEHFESK.GYSVYFREIRFGLNENDYLYEVHIL.
A0A1B1U668_9HELI/1-79 .MDFKLAKSTS....QSAET........TITLKEIQESVKD-Q.....EKFFYFSNENNHKDLLKIVEQFNKS.GRSAYLREAKFGLDEKEYIYELHII.
E4TYI5_SULKY/1-80 .MELKLARSEH....DSKPK........KIDLKKITEMVEKSN.....SSILYFDRENSHKDLLALQDHFEGE.GKSFYMREVKYGLSANEYMYEVHIL.
A0A1P8KQ01_9PROT/1-80 .MELLFARTEL....SEKPK........KVQLDKIKEDLQKDG.....EKIFYFDRDNSHKDMMALVDALEDE.GVNVYFREVKYGLADDEYMYEVHAL.
A0A2D3W1Q6_9PROT/1-80 .MDLKFARTEI....NAKPK........KAELAKIEASVAKEN.....SVIFYFDRENSHKDLLELQDYFEAK.GKSFYMNEVKYGLSDNEYMYQVHIV.
A0A329ZTF8_9HELI/1-80 .MEVKQARKQL....DGKID........KITSEQILEQLQENG.....QKILYLDKENSAKDIKKFCDIFSKK.GFSVHYHEIYYGLDSGDFLYEVHLI.
V8CKG6_9HELI/1-82 .MELKLAPMDTanisQASTQ........TIAVESLLESTSS--.....LQVVYLDKQNSQKDLQKAKTLLESK.GKVVYMGEVRYGLDAKDFIYEFRIL.
A0A2D3WAD2_9PROT/1-80 .MDLKFARTDI....TAKPK........KAELAKIEASLEKDD.....SVIFYFDRENSHKDLLELQDYFEAK.GKSFYMNEVKYGLSDNEYMYQVHII.
A0A2D3WFP6_9PROT/1-78 .MKLKLARTTL....KAKPK........IVEITKIEEELAD--.....KSIFYFDKDNSHKELKAVIEYFEEK.GYSVYMREVKYGLDENEYIYEVHII.
A0A2W6MXK7_9HELI/1-80 .MDIKLAREHI....NEKPT........KVSVKKLEEMLEEKK.....ANIFYCDKENSHKDMMALLEYFDKK.GKHAYFREVKYGLDEGDYMYEIHIL.
A0A2A2GU85_9HELI/1-82 .MELKVAKTDL....QSKKNe......vKISLDEVLRQYKEEN.....RHVFYFDGQNAHKDMQKAQNTIQKA.GYRVQLNEVRYGLDENNYIYEIHII.
Q7VGP7_HELHP/1-86 .MELKLAKSTLs.qaNAKNKvn....vaKISYEDMLKKCAQ-G.....EHIFYFDKENSHKEMQKVCASFQKA.GYNTYLNEVRYGLDEASYIYELHII.
A0A4Q0XQ92_9PROT/1-80 .MDVLLARKEL....TEKPK........KVQLDKLIEQLKEAG.....EKIFYFDKDNSHKDMMALVDTLEAE.GFNVYFREVRYGLADDEYMYEVHAL.
A0A3D8IG72_9HELI/1-80 .MELKLAKKEL....EDEQQ........TISLKEIQNQVETNG.....SATFYLDNDNPIKDIQKMRATLDKN.LKSVHLNELRYGIDKNSFLYELHII.
A0A7L8V4Y5_9PROT/1-76 .MEILLARTEL....SEKPK........KVKLEKLKEGGD---.....-KIFYFDKDNSHKDMMAVVESFEND.GYNAYFREVKFGLADDEFIYELHII.
C8PFL0_9PROT/1-80 .MQLKLARTEL....ASKPK........SVKIEDLQAQVEKSG.....QKIFYLDRENSQKDLAALVDFFDTK.GFSVYQRIVRYGLNENEYMYEVHIL.
A8ERE8_ALIB4/1-80 .MELLLARNEL....NEKPK........KVQLDKIKEDLEKDG.....QKIFYFDKDNSHKDMMALVSALEKN.GLNVYFREVRYGLADDEYMYEVHAL.
A0A3D8IZ33_9HELI/1-79 .MDFKLAKSTL....DSKSA........KISLKQIEEECAK-E.....GKIYYFSNENAHKDLLKIIGAFNTQ.GRNAYLHETKYGLDEKEYIYELHII.
E7G5A2_9HELI/1-80 .MELRLAKMDR...kQSKLY........SISLEELYQKALK-K.....EHIFYFAPTNSHKDMLQAVAFLEKQ.NCRVHLSEVQVSSDEKDFIYQLHII.
A0A363CZ36_9PROT/1-80 .MELLFARNEL....NEKPK........KVQLDKIKEDLKKDG.....QKIFYFDRDNSHKDMMALVDALEKE.GSNVYFREVKYGLADDEYMYEVHAL.
A0A345J836_9PROT/1-80 .MELLFARNEL....TEKPK........KVQLEKIKEELSKVG.....EKIFYFDRDNSHKDMMALVDALEAE.GFNVYFREVKYGLADDEYMYEVHAL.
A7GZE0_CAMC5/1-80 .MELKLARTEI....DAKPK........TISLDKIEAAVSKEG.....QKIFYFDKENSHKQLIALVEFFEEK.GLSVYHRTVRYGLDDNDYMYEVHIL.
A0A329ZF30_9HELI/1-83 .MELKIARADL....HTKKKn.....eaKISLDEIKTRVQEHN.....EHAFYLDGTNTHKDMQKAKASLEKS.GLRVQLNEVRYGLDDNTYIYELYV-v
A0A3D8HX75_9HELI/1-80 .MNLKLARMNL....NDKPK........TITLEEIEKQVKEKG.....NTTFYLDRENSLKDLEKICAHFEKS.AKSTHFHELRFGLDKDCILYELHII.
A0A5P8P2M1_9PROT/1-80 .MDLKFARTEL....DAKPK........KADIKKIEESVEKNG.....SVIFYFDRENSHKDLLELQDYFEEK.GKGFYMNEVKFGLSDNEYMYQVHII.
A6Q532_NITSB/1-80 .MELKLARQEL....SGKPK........TISVEKIEEAVQKEG.....NKIFYFDRENSHKDLVELVEHFEEK.GYSVYFREVKYGLDENDYIYEVHIL.
A0A268U5L9_9HELI/1-81 .MDLKLAKMDL....KQDCK........ISSLADILKIANEHK....rGKIFYLDKDNSEKDLKKAISTFTSK.GKTCFLREIKYGLDEKDYIYELHLL.
B9L7T4_NAUPA/1-76 .MTLKLISTDN....NIIEK........--TYEEFLKEIKP--.....NSFFYFHKDTSYKDLKDLIDKLEND.GYSVYFREVKFGLDEGAYMYELHII.
A0A7M1AVJ8_9PROT/1-80 .MDLKLVRMEL....DAKPK........KIDLAKIESLVEKEK.....SVILYFDRENSHKDLLALQDHFEAE.GKSFYMNEVKYALSDNDYMYQVHIM.
A0A268T8T2_9HELI/1-80 .MELILAKTKL....EDKTQ........KITLEKLAEKLNPEY.....NHMIYFDKSNNHKDLLKVVSFFQNK.GKSAYLSEVKFGLDEKDYIYELHII.
Q30PR0_SULDN/1-80 .MDLKFARTDV....TAKPK........KAELAKIEAAVEKDE.....SVIFYFDKENSHKDLLELQDYFEAK.GKSFYMNEVKYGLSDGEYMYQVHII.
A0A3D8ILJ8_9HELI/4-87 k-ELKLAKTSIk..sETATK........SITFDKMAEIIEKNGk...kGAVFYLDRDNQEKDIKKLEAFFKKK.KRAVLVRELHFTMDSKDYIYEVHIL.
A0A6M0L1Z1_9PROT/1-78 .MKLKLARASV....TAKPK........LIELSKIEEDLEK--.....KSIFYFDKENSHKDLKTLIEHFEEM.EYSVYMREVKFGLNDDEFIYEVHIV.
A0A6G5QHV6_9PROT/1-80 .MELKLARSEL....NAKPK........AISLDKIEQSVSKEG.....QKIFYFDKENSHKQLIALVEFFEEK.GLSVYHRVVKYGLDENDYMYEVHIL.
I7HE50_9HELI/1-83 .MELKLAKNTL....NTKNKtn....avKISCEDILKKLTQ-G.....ENIFYFDKENSHKDMQKACAFFQKA.GHSTYLNEVRYALDEGSYIYELHIL.
Q0PB54_CAMJE/9-88 .MELKLARTLI....NEKPK........NISLEKIEEAIEKEG.....QKFFYFDKDNTHKQLIALVNHFEKK.GVSIYHRTVKYGLDDNDFMYEVHIL.
T0JSB7_9PROT/1-80 .MDLKFARTDI....ETKPK........KVDLDKLEASVEKEG.....SMIFYFDKENSHKDLLELQDHFEQK.GKSFYMSEVKYGLSDGEYMYQVHII.
A0A7M1LGH3_9PROT/1-80 .MELKIARKEL....NSAPK........GISLENIESEVKKSG.....QKIYYFDRENSHKDLIALIEHFETK.GMSAYLRTVKYGLDESEYMYEVHIL.
E6WZ14_NITSE/1-78 .MKLKLARTTL....KAKPK........SVELSKIEEMLPQ--.....KSIFYFDRDNSHKDLKALIEHFEEE.GYNVYMREVKYGLNEDEYIYEVHIV.
V8CA71_9HELI/1-90 .MELKLASMDLgqtlA---KgqakpqttSIVIEDLANEVESKE....gMQILYFDRSCKDKDLKKAKALIEAK.GKTVYMGEVRYGLDSADMIYEFRII.
D3UG84_HELM1/1-78 .MELKLAKTDQ....EVESK........IITLQEIYEQASQ--.....ERFFYFSRDNKEKDLQKVLQSFVDK.KRSAKLDKISYGLDEKDFIYELHII.
A0A4U7BGZ9_9PROT/1-80 .MDLKLARELP....HEKPK........TIALKKIEEAVDQEG.....QSFFYFDKENSHKDLLALVAHFEKK.GLSVYHRVVRYGLDDEDYMYEVHIL.
A0A099TYG1_9HELI/1-84 .MEIKVAKNSLk..sDASQS........ILTLEDMLSIVNENGk...rGAIFYLDRENPEKNIKKIETFFKGK.DHATIIREVRISMDEKDYIYEIHVL.
A0A1X9STV5_9PROT/1-80 .MELKLARAEL....DAKPK........TISLEKIESAALKDG.....GKIFYFDRDNSHKQLIALVEHFENK.GLSVYHRTVKYGLDENDYMYEVHIL.
A0A5C8L5Y4_9PROT/1-80 .MDLKIARTSV....DEKPK........SISLESIEKAIDKEG.....QKFFYFDKDNAHKQLIALVEHFEKK.GKCVYHRTIKYGLDEADYMYEVHIL.
#=GC seq_cons .MELKLARs-l....ssKPK........pIsL-KIccplpcps.....ppIFYFD+-NSHKDLhtLl-aFEcK.GholYhREVKYGLD-s-YhYEVHIl.
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