#=GF ID Haemocyan_bet_s
#=GF AC PF14830.10
#=GF DE Haemocyanin beta-sandwich
#=GF AU Eberhardt R;0000-0001-6152-1369
#=GF SE CATH:1js8_B_02
#=GF GA 24.00 24.00;
#=GF TC 29.10 26.40;
#=GF NC 23.00 21.00;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 12767214
#=GF RT The structure of a functional unit from the wall of a gastropod
#=GF RT hemocyanin offers a possible mechanism for cooperativity.
#=GF RA Perbandt M, Guthohrlein EW, Rypniewski W, Idakieva K, Stoeva S,
#=GF RA Voelter W, Genov N, Betzel C;
#=GF RL Biochemistry. 2003;42:6341-6346.
#=GF RN [2]
#=GF RM 9614947
#=GF RT Crystal structure of a functional unit from Octopus hemocyanin.
#=GF RA Cuff ME, Miller KI, van Holde KE, Hendrickson WA;
#=GF RL J Mol Biol. 1998;278:855-870.
#=GF DR INTERPRO; IPR028999;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This antiparallel beta sandwich domain occurs in mollusc
#=GF CC haemocyanins. Each mollusc haemocyanin contains several globular
#=GF CC oxygen binding functional units. Each unit consists of an
#=GF CC alpha-helical copper binding domain (Pfam:PF00264) and an
#=GF CC antiparallel beta sandwich domain [1-2].
#=GF SQ 89
#=GS A0A812CD65_SEPPH/1575-1682 AC A0A812CD65.1
#=GS A0A812CD65_SEPPH/325-434 AC A0A812CD65.1
#=GS A0A0L8GNM6_OCTBM/824-926 AC A0A0L8GNM6.1
#=GS A0A812CTY0_SEPPH/1150-1252 AC A0A812CTY0.1
#=GS A0A2T7PFF9_POMCA/177-279 AC A0A2T7PFF9.1
#=GS A0A812CBN1_SEPPH/1132-1239 AC A0A812CBN1.1
#=GS A0A6P7SER3_OCTVU/5715-5817 AC A0A6P7SER3.2
#=GS A0A2T7PFF9_POMCA/964-1034 AC A0A2T7PFF9.1
#=GS A0A6P7SER3_OCTVU/4472-4579 AC A0A6P7SER3.2
#=GS A0A2T7PF41_POMCA/769-871 AC A0A2T7PF41.1
#=GS A0A812CD65_SEPPH/2001-2103 AC A0A812CD65.1
#=GS A0A6P7SER3_OCTVU/3648-3749 AC A0A6P7SER3.2
#=GS A0A7E6FRZ6_OCTVU/2818-2920 AC A0A7E6FRZ6.1
#=GS A0A7E6FRZ6_OCTVU/1163-1265 AC A0A7E6FRZ6.1
#=GS A0A812CD65_SEPPH/1164-1266 AC A0A812CD65.1
#=GS A0A812CXG7_SEPPH/1451-1558 AC A0A812CXG7.1
#=GS A0A6P7SER3_OCTVU/3221-3330 AC A0A6P7SER3.2
#=GS A0A2T7PFG6_POMCA/122-223 AC A0A2T7PFG6.1
#=GS A0A2T7PF55_POMCA/1003-1103 AC A0A2T7PF55.1
#=GS A0A7E6EGY5_OCTVU/252-366 AC A0A7E6EGY5.1
#=GS A0A2T7PFG7_POMCA/1488-1597 AC A0A2T7PFG7.1
#=GS A0A6P7SER3_OCTVU/2793-2895 AC A0A6P7SER3.2
#=GS A0A2T7PFF3_POMCA/473-526 AC A0A2T7PFF3.1
#=GS A0A6P7SER3_OCTVU/1975-2077 AC A0A6P7SER3.2
#=GS A0A7E6FRZ6_OCTVU/750-851 AC A0A7E6FRZ6.1
#=GS A0A7E6EGY5_OCTVU/691-799 AC A0A7E6EGY5.1
#=GS A0A0L8I403_OCTBM/588-696 AC A0A0L8I403.1
#=GS A0A812CBN1_SEPPH/1558-1659 AC A0A812CBN1.1
#=GS A0A812CXG7_SEPPH/2441-2543 AC A0A812CXG7.1
#=GS A0A2T7PFG7_POMCA/1077-1178 AC A0A2T7PFG7.1
#=GS A0A812CD65_SEPPH/752-853 AC A0A812CD65.1
#=GS A0A0L8I403_OCTBM/148-262 AC A0A0L8I403.1
#=GS A0A2T7PFG7_POMCA/2625-2727 AC A0A2T7PFG7.1
#=GS X6NDA9_RETFI/269-372 AC X6NDA9.1
#=GS A0A6P7SDC4_OCTVU/1994-2096 AC A0A6P7SDC4.2
#=GS A0A812CBN1_SEPPH/2100-2202 AC A0A812CBN1.1
#=GS A0A2T7PF37_POMCA/373-477 AC A0A2T7PF37.1
#=GS A0A812CTY0_SEPPH/1460-1567 AC A0A812CTY0.1
#=GS A0A7E6FRZ6_OCTVU/2001-2103 AC A0A7E6FRZ6.1
#=GS A0A2T7PEM0_POMCA/1651-1760 AC A0A2T7PEM0.1
#=GS A0A2T7PFF9_POMCA/585-694 AC A0A2T7PFF9.1
#=GS A0A6P7SER3_OCTVU/1550-1657 AC A0A6P7SER3.2
#=GS A0A7E6FRZ6_OCTVU/323-432 AC A0A7E6FRZ6.1
#=GS A0A7E6FRZ6_OCTVU/1575-1682 AC A0A7E6FRZ6.1
#=GS A0A2T7PEM0_POMCA/863-965 AC A0A2T7PEM0.1
#=GS A0A6P7SER3_OCTVU/1139-1241 AC A0A6P7SER3.2
#=GS A0A6P7SDC4_OCTVU/1569-1676 AC A0A6P7SDC4.2
#=GS A0A812CBN1_SEPPH/722-823 AC A0A812CBN1.1
#=GS A0A812CXG7_SEPPH/1627-1724 AC A0A812CXG7.1
#=GS A0A2T7PFG7_POMCA/1880-1943 AC A0A2T7PFG7.1
#=GS A0A2T7PF37_POMCA/1-58 AC A0A2T7PF37.1
#=GS A0A812CXG7_SEPPH/1036-1143 AC A0A812CXG7.1
#=GS A0A812CTY0_SEPPH/725-832 AC A0A812CTY0.1
#=GS A0A6P7SDC4_OCTVU/2403-2510 AC A0A6P7SDC4.2
#=GS A0A6P7SDC4_OCTVU/318-427 AC A0A6P7SDC4.2
#=GS A0A812CHS0_SEPPH/272-355 AC A0A812CHS0.1
#=GS A0A2T7PEM0_POMCA/3296-3392 AC A0A2T7PEM0.1
#=GS A0A6P7SER3_OCTVU/299-408 AC A0A6P7SER3.2
#=GS A0A2T7PEM0_POMCA/2478-2586 AC A0A2T7PEM0.1
#=GS A0A2T7PF41_POMCA/364-466 AC A0A2T7PF41.1
#=GS A0A812CBN1_SEPPH/310-411 AC A0A812CBN1.1
#=GS A0A6P7SER3_OCTVU/2384-2491 AC A0A6P7SER3.2
#=GS A0A6P7SER3_OCTVU/4061-4163 AC A0A6P7SER3.2
#=GS A0A6P7SDC4_OCTVU/1158-1260 AC A0A6P7SDC4.2
#=GS A0A6P7SDC4_OCTVU/745-846 AC A0A6P7SDC4.2
#=GS A0A2T7PFF3_POMCA/69-155 AC A0A2T7PFF3.1
#=GS A0A6P7SER3_OCTVU/4897-4999 AC A0A6P7SER3.2
#=GS A0A2T7PEM0_POMCA/434-545 AC A0A2T7PEM0.1
#=GS A0A812CD65_SEPPH/2410-2517 AC A0A812CD65.1
#=GS A0A2T7PEM0_POMCA/2076-2178 AC A0A2T7PEM0.1
#=GS A0A812CV46_SEPPH/751-852 AC A0A812CV46.1
#=GS A0A2T7PEM0_POMCA/2887-2989 AC A0A2T7PEM0.1
#=GS A0A812CXG7_SEPPH/625-727 AC A0A812CXG7.1
#=GS A0A0L8FFZ3_OCTBM/168-275 AC A0A0L8FFZ3.1
#=GS A0A7E6FRZ6_OCTVU/2411-2518 AC A0A7E6FRZ6.1
#=GS A0A812CTY0_SEPPH/310-417 AC A0A812CTY0.1
#=GS A0A2T7PF55_POMCA/192-299 AC A0A2T7PF55.1
#=GS A0A0L8GNM6_OCTBM/312-414 AC A0A0L8GNM6.1
#=GS A0A2T7PFG7_POMCA/2270-2324 AC A0A2T7PFG7.1
#=GS A0A2T7PEM0_POMCA/1243-1345 AC A0A2T7PEM0.1
#=GS A0A812CD65_SEPPH/2819-2921 AC A0A812CD65.1
#=GS A0A2T7PFG7_POMCA/349-458 AC A0A2T7PFG7.1
#=GS A0A6P7SER3_OCTVU/5306-5413 AC A0A6P7SER3.2
#=GS A0A6P7SER3_OCTVU/726-827 AC A0A6P7SER3.2
#=GS A0A2T7PF41_POMCA/1-62 AC A0A2T7PF41.1
#=GS A0A2T7PF55_POMCA/610-712 AC A0A2T7PF55.1
#=GS A0A812CV46_SEPPH/324-433 AC A0A812CV46.1
#=GS A0A812CXG7_SEPPH/2032-2139 AC A0A812CXG7.1
#=GS A0A6P7SDC4_OCTVU/2812-2914 AC A0A6P7SDC4.2
A0A812CD65_SEPPH/1575-1682 ............RKAEDRILVGFLLQGVKASADVRIYICVPISqt.....eeNCnNYAGVFSILGGE..SEMPWKFDRLFRYEITGELQHLGLNQISQ......FRVKTEVIAVNGSSISRPIFPKPTIIYI-p.............
A0A812CD65_SEPPH/325-434 ............RQTRPRVYANFRLGGIQTSANIKIMLCIPSKdkr...hsdNCdNEAGQFFILGGI..HEMPWNFAYPYLHEITNIVNAVGLELEGD......YYVTVKITAINGTLLADDIIPHPTVSYI-p.............
A0A0L8GNM6_OCTBM/824-926 ...........i-QHEDRIFAGFLLRTIGQSADVNFDICTKDG.........DC.AFGGTFCILGGE..HEMFWAFDRLFKYDITTSLKQLRLDAHDD......FDIKVTIQGIDGHTLPASYFSPPTVFFSP..............
A0A812CTY0_SEPPH/1150-1252 ...........e-KQKDRVFAGFLLEGFGSSAYATFEICPDTG.........DC.HEGSHFSVLGGS..AEMPWAFDRLYKMEITNILRDMKLNFDSH......FTIKTKVVAQNGTELSENLLPEATII---rip...........
A0A2T7PFF9_POMCA/177-279 ............RQHDERVFAGFMLHGIGQSALVTLDVCEPSG.........PC.HPAGEFYILGDE..YEIPWQYDRLFQYEITDVLAKYKLEANDR......YSVQYSVIDLDGKKISSDIFGKVTVVVR-p.............
A0A812CBN1_SEPPH/1132-1239 ...........k-QEHDRVFAGFLLHGIKASADVRIYICVPTGtd.....eeNCgNYAGIFSVLGGN..SEMPWRFDRLFRYEITDSLKKLGLNQNSH......FRVITEVTAVNGSRIMQKIFPDPTIIFVP..............
A0A6P7SER3_OCTVU/5715-5817 ...........i-QHEDRVFAGFLLRTIGQSADVNFDICTKDG.........DC.VFGGTFCILGGE..HEMFWAFDRLFKYDITSSLKQLRLDAHDD......FEIKVTLNGIDGGILPHDYLSPPTVFFMP..............
A0A2T7PFF9_POMCA/964-1034 ............QKEKSRAFAGFLLGGIKTSAHVDILVCTSED.........VC.TEAGDFDVLGGT..AEMPWSFDRLYRYEITEL-----------......-----------------------------sttvtell......
A0A6P7SER3_OCTVU/4472-4579 ............RKAHDRIFAGFLLHGVKASADVHIYICVPTSkh.....eeNCaHEAGVFSVLGGE..SEMPWQFDRSFRYEITDQLKLLGLNQNSH......FRIKTEVIAVNGSSIHANIFPNPTIIYVP..............
A0A2T7PF41_POMCA/769-871 ...........l-RVKDRLFAAFLLSGVHTSARLHVTLQTGSG.........EGaVEVGSIYLLGGL..SERRWAHERAYKLDVTEAAARLELDPYST......FDFNVSLFDYKGQPLPY-TLPYPLVLYRP..............
A0A812CD65_SEPPH/2001-2103 ...........l-KQHDRIFAGFLLEGFGSSAYVTFAICNYYD.........QC.GMGSHFFILGGS..DEMPWAFNRLYLMEITDILRRMNINYNSP......FAVRLWAISPNGTIFPEGTLSEPTIIR--vp............
A0A6P7SER3_OCTVU/3648-3749 ...........d-KAKDRVFVGFLLMGIKTSANVDITVDSAGN.........T-.YNAGSITILGGS..KEMEWRFDRLYKYEITGALAELGVDMRAD......YSITLQITDINGTALPSTAIPDPIVIFTP..............
A0A7E6FRZ6_OCTVU/2818-2920 ...........s-KKKDRVYAGFLLRTIGQSADVEFEVCRKDG.........EC.KFAGTFCILGGK..HEMFWAFDRLYKYDITSTLEQLRLHAHDQ......FSITVSIKATDGSTLAPSLIPPPSIMYHP..............
A0A7E6FRZ6_OCTVU/1163-1265 ............RRAKDRIFVTFLLEGHKQSLLVEYYIRLHGS........tDR.NKAGEFYVLGSE..NEMPWKFDRVYKADITRQMEHLHLHYNDL......YHIEYTLKDMSGAEVTSLGLE-PAVIFEP..............
A0A812CD65_SEPPH/1164-1266 ............RKAKNRVFVTFMLEGLKKSLLVQYYIKDDAS.........DKkMKAGEFYILGSE..NEMPWKFDRSYKVDITQEMDVLNLHYAGS......YSIEYTMTDMKGNKIDDVELE-PTVIFEP..............
A0A812CXG7_SEPPH/1451-1558 ............RKSHDRVFAGFWLHGIKASADINIYICVPIGve.....hdDCdHKAGTFSVLGGE..TEMPWKFDRLFHYEITEHMKELHLTQESK......FHLTTKIIAANGTKLSNDIFPSPSVVWV-h.............
A0A6P7SER3_OCTVU/3221-3330 ...........h-QQHPRAFANFRLGGIKTSANVRVAVCVPTDdkr...hsdNCnNHVGSFFILGGV..HEMTWNFGYPFLFEITDVVKSLGVPLDGN......YYIHADVTAINGTLLPDGTIPRPTVTYI-p.............
A0A2T7PFG6_POMCA/122-223 ...........l-RDHDRVYAGFVLSGIGVSATANVKLVPQGG.........DP.VDVGSFYILGGD..GEMPWAYERVYKYDVTDALEKLGLNAYSN......FGFQVTLTKYNGEQLDASLAT-PVVI---srp...........
A0A2T7PF55_POMCA/1003-1103 ............RQSRERVFVGFMLHGIQRSALVVLNLCQV--.........TC.QKAGEFYILGDA..NEMPWKYDRLFKYEITRLLAELKLRADDP......YRVSYTVYDLNGQELEDNLFGNVTIV---rdt...........
A0A7E6EGY5_OCTVU/252-366 ............RRSKPRSFASFQLRAIKASAKFRVLVCVSPEsdtahvladDCsNDAGSFFVLGGDdiHQQKWDYGYPYLFEITDVVKSLGVPLDGD......YYVRADISALNGTQLKDDIIPPPTVSYI-p.............
A0A2T7PFG7_POMCA/1488-1597 ............QRAQDRLFAGFLLHNIGTSADVQLFICVATGng.....erNCnHPAGSFSVLGGE..TEMSFIFDRLYKYDISDPVRKLGLKLDSAg....dIDLEIKIRAYNGSYLESSVLRRPSLIFVP..............
A0A6P7SER3_OCTVU/2793-2895 ...........i-QHEDRVFAGFLLRTIGQSADVNFDICTNDG.........DC.AFGGTFCILGGE..HEMFWAFDRLFKYDITTSLKHLRLDAHDD......FDIKVTIKSIDGHTLPNSYLTPPTVFFVP..............
A0A2T7PFF3_POMCA/473-526 ........rrar-------------------------------.........--.------------..-------DRTF-VEITDALSALSLNYDDN......YKISLAIKDVNGKDWPENTFSHSTIIHE-e.............
A0A6P7SER3_OCTVU/1975-2077 ............QREHDRVFAGFLLSGFGSSAYATFEICVEGG.........EC.HEGSHFAVLGGS..TEMPWAFDRLYKIEITDVLANNNLAFDSP......FTIKTKIVAQNGTELPAGILPEATVV---rip...........
A0A7E6FRZ6_OCTVU/750-851 ............KKTHDRVFAGFLFGGIKTSANIDLYVVAAGN.........E-.YLASPISILGGT..KEMPWRFDRLFRQEITDSLKALGVDPFGD......FTLRVDIKDVNGTALPSTIISQPIVIFEP..............
A0A7E6EGY5_OCTVU/691-799 ...........l-KKKDRVFIGFLLRGIKTSAKIQVAVNENSRdn....vkrSVpMILASILVYGSR..EENDWGFDRYYKHEITHSLLRLGYNYDDK......IHLNVYAEDINGTTLPDDILPEPVIIYVP..............
A0A0L8I403_OCTBM/588-696 ...........l-KKKDRVFIGFLLRGIKTSAKIQVTVNENFRdn....dkrSVpTILASILVYGSP..QENEWSFDRYYKHEITHSLLLLDYKYDDK......IPLNVYAEDINGTTLPDAVLPEPVIIYVP..............
A0A812CBN1_SEPPH/1558-1659 ...........e-KQKDRVFVGFLLQGFGSSAYATFEVCSDEG.........AC.HEGSHFSVLGGS..AEMPWAFDRLYRMEITNILKEMHLEADSH......FTIKSKIIAHNGTELF-HVLPEPTII---rip...........
A0A812CXG7_SEPPH/2441-2543 ...........i-QAKDRVFAGFLLRAIGQSADVNFDICRKDG.........EC.KFGGTFCVLGGK..HEMAWAFDRLFLYDISRSLLQLRLDAHDD......FDVKVTIMGIDGKSLPSTLLPPPTILFKP..............
A0A2T7PFG7_POMCA/1077-1178 ............RQHDERVFAGFMLRGIGKSALVTLEVCEPSG.........TC.HPAGEFYILGDE..YEIPWQYDRLFKYEITDVLEEFKLEANDR......YSVQYSVIDLDGTK---------------svvtssarsllsfd
A0A812CD65_SEPPH/752-853 ...........n-KATDRVFAGFLFMSIYTSATVDLFVIVDND.........E-.IRIGSIAILGGT..KEMPWRYDRLYKHEITAALIALGVDIHGE......YFLRVEIKEMNGTAIPASAVPPPIVIFVP..............
A0A0L8I403_OCTBM/148-262 ............RRSKHRSFASFHLRAIKTSAKFRVLVCVPRKgktahvltdDCnNDAGSFFVLGGDdiHQQKWDYGYPYLFEITDVVESLGVPLDGD......YYVHADISALNGTQLRDDIIPAPTVSYI-p.............
A0A2T7PFG7_POMCA/2625-2727 ............RRSEDRVFANFMLQGFKASADVTFDLCDADN.........HC.SFAGTFAVLGGP..LEMDWHFDRLFQYDVTSVFNQMHLRPDSV......YHFDVHITAINGTQLASSLLESPSVSFVP..............
X6NDA9_RETFI/269-372 ..........ky--ESERLYLGWYLPDLPFTYRIHYAAKKYGT.........NTvIVNGSFAKLGSS..PTVAGLNKFLFRVDITEAMNSSGLALDNL......VEVDVFVTSDKDSNTPAVIIPHPAIIYR-s.............
A0A6P7SDC4_OCTVU/1994-2096 ............QREHDRVFAGFLLSGFGSSAYATFEICVEEG.........EC.HEGSHFAVLGGS..TEMPWAFDRLYKIEITDVLANNNLAFDSP......FTIKTKIVAQNGTELPAGILPEATVV---rip...........
A0A812CBN1_SEPPH/2100-2202 ...........y-QEKDRVFAGFLLRTIGQSADVNFDVCRKDG.........DC.TFGGTFAILGGQ..HEMFWAFDRLFLYDISKSLVHLRLDAYDN......FDIKVTIKGIDGQELPSKLLPPPTVLFKP..............
A0A2T7PF37_POMCA/373-477 ............QKEKPRVFAGFLLHSLGTSAHVTFSVCSGEEy.......qEC.TLAGDFNVLGGS..AEMPWRFDRLYRYEITDVLKTKGLKVDDM......FQIKVVITAQNGTVLDSNSLPQPTVIFMP..............
A0A812CTY0_SEPPH/1460-1567 ............QKQKDRVFAGFLLHGIKTSADVHLKVCN-DA.........DC.HEAGVVFILGGE..TEMPWHFDRNYKMDITDVLQKMGVELETVfdheskLHLEVHIESVDGTTLDPGSLPKPSLIYI-p.............
A0A7E6FRZ6_OCTVU/2001-2103 ............QKQRERMFAGFLLKGIGQSAYATFQVCDKKN.........SC.HDGSHFSILGGS..AEMSWAFDRLYVMEITDILHDMGLKFDSH......FHIHHHIKTANGTDLPSDLIPQATII---rip...........
A0A2T7PEM0_POMCA/1651-1760 ............QRSRDRLFAGFLLHNIGTSADVHIRLCVATGng.....ehNCnHDAGEFSILGGE..TEMPFIFDRLYKFDISEPVRKLGFRLDNPg....nLDLDIKIQAFNGSYLDPSILRRPSLIFVP..............
A0A2T7PFF9_POMCA/585-694 ............QRAQDRLFAGFLLHNIGTSADVQLFICVATGng.....erNCnHPAGSFSVLGGE..TEMPFIFDRLYKYDISDPVRKLGLKLDSAg....dIDLEIKIRAYNGSYLESSALRRPSLIFVP..............
A0A6P7SER3_OCTVU/1550-1657 ............RKAHDRIFAGFLLHGVKASADVHIYICVPTSkh.....eeNCaHEAGVFSVLGGE..SEMPWQFDRSFRYEITDQLKLLGLNQNSH......FRVKTEVIAVNGSSIHANIFPNPTIIYVP..............
A0A7E6FRZ6_OCTVU/323-432 ............RQSHPRSFANFRLGGIKTSANVHISVCIPSKdsr...ksdDChHDAGEFFILGGK..REMPWDFGYPYLHDITDTVKSLGLELDGN......YYLKAEVTAINGSHLPSDIIPKPIVTYI-p.............
A0A7E6FRZ6_OCTVU/1575-1682 ............RHQQDRVFAAFLLHGVKASADVRIYICAPTGrn.....qeNCaNYAGVFSILGGE..SEMPWRFTHLFRYEITDSLMKLGLNHNSH......FRISTEVRAVNGSKIEKKIFPEPTIIFVP..............
A0A2T7PEM0_POMCA/863-965 ............RRTEDRTFVGILLHSIGVSAKVEVEIKKSGV.........AP.YKVGVLAVLGGE..AEMPWNFDRVVKVEITKALTDLGLSYDDN......FDVILSITDVNGIPLPEDTFSHHTIIHD-d.............
A0A6P7SER3_OCTVU/1139-1241 ............RRMKGRVFATFMLEGIKQSALVEYYIRAHGA........tDQ.VKAGEFYVLGSA..NEMPWKFDRVYKADITKQMKEAHLHYNDQ......YHIEYHVKDLAGAEIADVNLE-PAIVYEP..............
A0A6P7SDC4_OCTVU/1569-1676 ............RKAHDRIFAGFLLHGVKASADVHIYICVPTSkh.....eeNCaHEAGVFSVLGGE..SEMPWQFDRSFRYEITDQLKLLGLNQNSH......FRVKTEVIAVNGSSIHANIFPNPTIIYVP..............
A0A812CBN1_SEPPH/722-823 ............RKAKNRVFVTFMLEGLKKSLLVQYYIKDDAS.........DKkMKAGEFYVLGSE..NEMPWKYDRAFKSDITHVMDEMNLHYTDK......YHIEYTVTDMKGETVDVKLS--PTVVYQP..............
A0A812CXG7_SEPPH/1627-1724 ......khryac-----------CLHGFGSSAYATFEICPDTG.........DC.HEGSHFSVLGGS..AEMPWAFDRLYKMEITNILRDMKLNFDSH......FTIKTKVVAQNGTELSETLLPEATII---rip...........
A0A2T7PFG7_POMCA/1880-1943 ............QKEKSRAFAGFLLGGIKTSAHVDIWVCTTEN.........VC.TEAGDFDVLGGT..AEMPWSFDRLYRYEITE------------......-----------------------------lr............
A0A2T7PF37_POMCA/1-58 ............-------------------------------.........--.------------..--MPFTFDRLYKYDISEPIRQLGLKLDSAa....eFELEIKIRAFNGSYLEPDLVDKPSIIFL-p.............
A0A812CXG7_SEPPH/1036-1143 ...........n-KGHDRIFAGFLLHGIKASADVRIYICVPTGvg.....eeNCaNYAGIFSVLGGE..TEMPWRFDRLFRYEITSELKKLGLNHNSH......FRVAMEVTAVNGSRITQKVFPNPTIVFVP..............
A0A812CTY0_SEPPH/725-832 ............RKSRDRVFAGFMLHGVKASADVRIYICVPTGvv.....leNChNYAGVFSILGGE..TEMPWKFDRVYRYELTDEINKLGLSANSQ......FRISTEVTAVNGSKILQKIFPTPSVIFVP..............
A0A6P7SDC4_OCTVU/2403-2510 ............RQSTDRVFASFLLFGIKTSADVHLKLCK-DT.........TC.EDAGVVFVLGGD..NEMPWHFDRTYKMDITHVIHKMHIPLEDLyvhgstIHLEVVIETVDGKVLDSSSLPAPTMIYVP..............
A0A6P7SDC4_OCTVU/318-427 ...........h-QQHPRAFANFRLGGIKTSANVRVAVCIPTDdkr...hsdNCnNHVGSFFILGGV..HEMTWNFGYPFLFEITDVVKSLGVPLDGN......YYIHADVTAINGTLLPDGTIPRPTVTYI-p.............
A0A812CHS0_SEPPH/272-355 ............RKSKARAFANFRLGGIKTSANVRISICIPNKdgr...hsdNCdNYAGEFFILGGK..HEMPWHFAYPYLYEITDKVHALGLS----......-----------------------------fwtqitt.......
A0A2T7PEM0_POMCA/3296-3392 ...........l-RAKDRVFAGLVLSGFRTSATAHVEVGASGK.........ST.QDEGSFYILGGP..KELPWAYERVYKYDITHAVTELSVSPYSP......INITVTLTGYDGSSV--------------ivrrgtqi......
A0A6P7SER3_OCTVU/299-408 ...........h-QQHPRAFANFRLGGIKTSANVRVAVCVPTDdkr...hsdNCnNHVGSFFILGGV..HEMTWNFGYPFLFEITDVVKSLGVPLDGN......YYIHADVTAINGTLLPDGTIPRPTVTYI-p.............
A0A2T7PEM0_POMCA/2478-2586 ...........h-QSKPRIFAGFLLHGIGVSAEVRCSICVTRT.........RC.ARAGAFFVLGSD..VEMPWSFDRLYKYDITQALEALSIRPEDVfdaqasFNLNVDIIAVNGTKLPSSSLPTPTIIFEP..............
A0A2T7PF41_POMCA/364-466 ............RRQEDRVFANFMLHGIRSSADVSFDICDAQN.........HC.IFAGTFAILGGP..LEMPWVFDRLFKYDVTSVFKQLHLRPDSE......YRFKMRLTAVNGTELDPHMLHAPSVSFL-p.............
A0A812CBN1_SEPPH/310-411 ..........ne--AKDRVFAGFLLMGIHTSANVDLYVVAGGN.........E-.YMAGSIAILGGS..KEMSWRFDRVYKHDITSALAALGVDKFGD......YTLRVDIKDVNGTALPSTIIPAPIVIYAP..............
A0A6P7SER3_OCTVU/2384-2491 ...........h-QNTDRVFASFLLFGIKTSADVHLKLCN-DT.........TC.EDAGVVFVLGGD..NEMPWHFDRTYKMDITHVIHKMHIPLEDLyvhgstIHLEVVIETVDGKVLDSSSLPAPTMIYVP..............
A0A6P7SER3_OCTVU/4061-4163 ............RRMKGRVFATFMLEGIKQSALVEYYIRAHGA........tDQ.VKAGEFYVLGSA..NEMPWKFDRVYKADITKQMKEAHLHYNDQ......YHIEYHVKDLAGAEIADVNLE-PAIVYEP..............
A0A6P7SDC4_OCTVU/1158-1260 ............RRMKGRVFATFMLEGIKQSALVEYYIRAHGA........tDQ.VKAGEFYVLGSA..NEMPWKFDRVYKADITKQMKEAHLHYNDQ......YHIEYHVKDLAGAEIADVNLE-PAIVYEP..............
A0A6P7SDC4_OCTVU/745-846 ...........d-KAKDRVFVGFLLMGIKTSANVDITVDSAGN.........T-.YNAGSITILGGS..KEMEWRFDRLYKYEITGALAELGVDMRAD......YSITLQITDINGTALPSTAIPDPIVIFTP..............
A0A2T7PFF3_POMCA/69-155 rtivcdhdeedd----------------------------SHD.........HC.EFAGDIFILGGA..NEMPWEFNLPYHFDISKAVERLGKKLGGD......YIVTAELYSVNGTSLDPSLLPRPVGVHRP..............
A0A6P7SER3_OCTVU/4897-4999 ............QREHDRVFAGFLLSGFGSSAYATFEICVEEG.........EC.HEGSHFAVLGGS..TEMPWAFDRLYKIEITDVLANNNLAFDSP......FTIKTKIVAQNGTELPAGILPEATVV---rip...........
A0A2T7PEM0_POMCA/434-545 ..........rs--GRERAFATFSLHGLGFSANVRVKVCEHLEedyaheetsHC.EFAGDIFILGGA..NEMKWEFTLPYYFDISDAVLRLGQPLDGN......YIIQTEVFSVNGTELEAHVLPDPVGAHR-p.............
A0A812CD65_SEPPH/2410-2517 ............QKRQDRIFAGFLLHGIKISADVQLKVCN-DT.........DC.AAAGVLFVLGSP..TEMPWHFDRNYKMDITDVFKKMRIPFEDLfkqnsrIHLEVEIKSVEGKKLDAKTIPKPSLIYSP..............
A0A2T7PEM0_POMCA/2076-2178 ............QKEKGRVFVGLLLGGIRTSAHVEIIVTAPGG.........KD.TPAGDFNILGGS..AEMPWSFDRLYRYEITDVLKKEGLKKTDS......FNVSVTITAMNGTTLDSSLIPTPSVIYKP..............
A0A812CV46_SEPPH/751-852 ...........a-KSKDRVFAGFLLMGIHTSANVDLYVVAGGN.........E-.FSVGSIAILGGS..KEMSWRFDRVYKHEITHALEALGVDKFAE......YTLRVDIKDVNGTALPPTTIPAPIVIFVP..............
A0A2T7PEM0_POMCA/2887-2989 ............RRDEDRIFANFMLAGFGASADVTFELCDKEN.........HC.IFAGTFAVLGGP..LEMHWKFDRLFKYDVTAVFKQLHLRPDSE......YHFDVHIRAVNGSELSSSLLEPPSVSFVP..............
A0A812CXG7_SEPPH/625-727 ............RKSKNRVFVTFMLEGLKKSLLVEYYIKDDGS.........DNqMKAGEFYVLGSE..NEMPWEFDRAYKSDITHVMDEMKLHYTDK......YHVEYKITDMTGAEVTDIKLE-SSVVFEP..............
A0A0L8FFZ3_OCTBM/168-275 ............RKAHDRIFAGFLLHGVKASADVHIYICVPTSky.....eeNCaHEAGVFSVLGGE..SEMPWQFDRVFRYEITDQLKLLGLNQNSH......FRVKTEVTAVNGSSIHAKIFPHPTIIYVP..............
A0A7E6FRZ6_OCTVU/2411-2518 ...........l-KQKDRVFATFLLHGIKTSADVHLKLCD-DK.........SC.SAAGVVFILGGE..TEMPWHFDRTYKMDITKVMKEKGIAMESLfhhdskVHLEMEIITIDGTVLDQNSLPKPSLVYSP..............
A0A812CTY0_SEPPH/310-417 ...........n-KGHDRIFAGFLLHGIKASADVRIYICVPTGvg.....eeNCaNYAGIFSVLGGE..TEMPWRFDRLFRYEITSELKKLGLNHNSH......FRVAMEVTAVNGSRITQKVFPNPTIVFVP..............
A0A2T7PF55_POMCA/192-299 ............RRARERAFAAFTLKGLGFSANVRVKVCQRDAtg....sdgHC.EFAGDIFLLGGA..NEMAWEFNLPYYFDVSDAVVRLGVPLDGD......FLVKAELYSVNGTLLSSGLLPPPIGA---hrp...........
A0A0L8GNM6_OCTBM/312-414 ............RRMKGRVFTTFMLEGIKQSALVEYYIRAHGS........tDQ.VNAGEFYVLGSA..NEMPWKFDRVYKADITKQMKEANLHYNDQ......YHIEYHVKDLAGAEIADVNLE-PAIVYEP..............
A0A2T7PFG7_POMCA/2270-2324 ..........ev-------------------------------.........--.------------..-----------RYDITDTLNELHIRPEDVfnadapFSLRYEIIAVNGTALPRSSLSKPTIIFKP..............
A0A2T7PEM0_POMCA/1243-1345 ............RQTDDRIFVGFMLRGIKKSALVSFRIIDSKN.........ES.HKGGEFYILGDE..NEIPWQYDRLFKFEITRELATNNIDQRDP......FRIEYDVYNLAGEKISNSTYGQVTIINE-p.............
A0A812CD65_SEPPH/2819-2921 ...........y-QEKDRVFAGFLLRTIGQSADVNFDVCRKDG.........EC.TFGGTFSILGGQ..HEMFWAFDRLFLYDISKSLLHLRLNAYDD......FDVKVTIWGIDGQELPSNIFSPPTIMFRP..............
A0A2T7PFG7_POMCA/349-458 ...........r-HARERALASFTLHGLGFSANVRIKVCDHDDddd..qshsHC.EFAGDIFILGGA..NEMPWEFNLPYHFDISKAVEHLGKKLNGD......YVVTAELYSVNGTSLNPNLLPRPVGVYRP..............
A0A6P7SER3_OCTVU/5306-5413 ............RQNTDRVFASFLLFGIKTSADVHLKLCK-DT.........TC.EDAGVVFVLGGD..NEMPWHFDRTYKMDITHVIHKMHIPLEDLyvhgstIHLEVVIETVDGKVLDSSSLPAPTMIYVP..............
A0A6P7SER3_OCTVU/726-827 ...........d-KAKDRVFVGFLLMGIKTSANVDITVDSAGN.........T-.YNAGSITILGGS..KEMEWRFDRLYKYEITGALAELGVDMRAD......YSITLQITDINGTALPSTAIPDPIVIFTP..............
A0A2T7PF41_POMCA/1-62 ............-------------------------------.........--.------------..--MQWSFDRLYRHDITQALLTVSVRPQDLftehtpFTLDYSITAVNGTQLPRSLMPPPTIIYEP..............
A0A2T7PF55_POMCA/610-712 ..........rg--NRDRTFVGVKLHNIGVSAWVKLYISVPGG.........ET.YLANSFAVLGGE..REMTWTFDRLFKVEITDALLAIGRNYDED......FDVTLDITDVHQQKWSGDTFSHTTIFHQP..............
A0A812CV46_SEPPH/324-433 ............RKSKARAYANFRLGGIKTSANVRIKLCIPTKdkr...qsdNCdNDAGQFFILGGV..HEMPWDFAYPYLHEITDTVNSLGLKLDSN......YYVTAEVTAINGTLMPSEVIPYPTVTYVP..............
A0A812CXG7_SEPPH/2032-2139 ............QKQKDRVFAGFLLHGIKTSADVHLKVCN-DA.........DC.HEAGVVFILGGE..TEMPWHFDRNYKMDITDVLREMHIPMEALfeheskIHLEVEIQTVDGNTLDSGILPKPSLIYAP..............
A0A6P7SDC4_OCTVU/2812-2914 ...........i-QHEDRVFAGFLLRTIGQSADVNFDICTKNG.........EC.TFGGTFCILGGE..HEMFWAFDRLFKYDITSSLNKLRLHAHDD......FEIKVTIKAIDGHTLPNKYLTPPTIFFVP..............
#=GC seq_cons .............+p+DRlFAGFhLpGItsSApVphhlCssss.........sC.p.AGsFhlLGGp..pEMPWpFDRlY+a-ITcslppLsLphssp......aplcsclpulNGopLssshlPtPollahP..............
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