#=GF ID Herpes_TK
#=GF AC PF00693.22
#=GF DE Thymidine kinase from herpesvirus
#=GF PI TK_herpes;
#=GF AU Bateman A;0000-0002-6982-4660
#=GF SE Pfam-B_186 (release 2.1)
#=GF GA 25.00 25.00;
#=GF TC 30.30 40.60;
#=GF NC 23.80 19.30;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP Domain
#=GF WK Thymidine_kinase_from_herpesvirus
#=GF CL CL0023
#=GF RN [1]
#=GF RM 7552712
#=GF RT Crystal structures of the thymidine kinase from herpes simplex
#=GF RT virus type-1 in complex with deoxythymidine and ganciclovir.
#=GF RA Brown DG, Visse R, Sandhu G, Davies A, Rizkallah PJ, Melitz C,
#=GF RA Summers WC, Sanderson MR;
#=GF RL Nat Struct Biol 1995;2:876-881.
#=GF DR INTERPRO; IPR001889;
#=GF DR SCOP; 1kin; fa;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF SQ 64
#=GS A0A2D1A3F7_9GAMA/418-645 AC A0A2D1A3F7.1
#=GS L0N5F5_HHV1/56-329 AC L0N5F5.1
#=GS Q6R5W6_9ALPH/26-307 AC Q6R5W6.1
#=GS A0A2D0TCK7_CHV9D/20-297 AC A0A2D0TCK7.1
#=GS Q8UZE6_9GAMA/291-546 AC Q8UZE6.1
#=GS KITH_EHV1B/32-308 AC P69185.1
#=GS E9M5K4_9GAMA/267-461 AC E9M5K4.1
#=GS KITH_HHV11/56-329 AC P0DTH5.1
#=GS A0A0B5D5E2_9GAMA/236-465 AC A0A0B5D5E2.1
#=GS A0A060CY10_9GAMA/245-491 AC A0A060CY10.1
#=GS KITH_EHV2/301-525 AC Q66624.2
#=GS KITH_EBVB9/291-551 AC P03177.2
#=GS U5NIU8_9GAMA/247-471 AC U5NIU8.1
#=GS KITH_HHV8P/260-491 AC F5HB62.1
#=GS A0A1S6JLN8_HSVA1/17-300 AC A0A1S6JLN8.1
#=GS A0A3Q8JCB4_9GAMA/177-390 AC A0A3Q8JCB4.1
#=GS A0A1P7U0R0_9ALPH/26-307 AC A0A1P7U0R0.1
#=GS A0A286MM58_9ALPH/16-291 AC A0A286MM58.1
#=GS Q5ZR74_9ALPH/35-316 AC Q5ZR74.2
#=GS A0A068ER26_9ALPH/30-312 AC A0A068ER26.1
#=GS KITH_GAHVM/26-307 AC Q9E6P5.1
#=GS Q156E1_9ALPH/31-312 AC Q156E1.1
#=GS O41940_MHV68/333-515 AC O41940.1
#=GS Q2QBF4_CHV16/36-311 AC Q2QBF4.1
#=GS A0A0K1R1A9_9ALPH/25-305 AC A0A0K1R1A9.1
#=GS A0A077B9Q8_9ALPH/29-306 AC A0A077B9Q8.1
#=GS A0A060Q1U8_9ALPH/9-282 AC A0A060Q1U8.1
#=GS Q3C1Z5_9ALPH/56-330 AC Q3C1Z5.1
#=GS Q91SC6_9ALPH/12-283 AC Q91SC6.1
#=GS KITH_VZVD/19-298 AC P09250.1
#=GS A0A1Z1NEF9_9GAMA/343-603 AC A0A1Z1NEF9.1
#=GS G9CUD0_9ALPH/26-307 AC G9CUD0.1
#=GS A0A0M3T961_9GAMA/194-435 AC A0A0M3T961.1
#=GS KITH_PSHV1/11-294 AC Q6UDK9.1
#=GS A1BM10_9GAMA/252-479 AC A1BM10.1
#=GS Q98143_HHV8/260-491 AC Q98143.1
#=GS M4JX30_ELHV1/61-260 AC M4JX30.1
#=GS Q993J7_9GAMA/348-569 AC Q993J7.1
#=GS KITH_ALHV1/245-480 AC O36371.1
#=GS Q77L27_MEHV1/17-299 AC Q77L27.1
#=GS A0A0S1TPL4_9BETA/55-256 AC A0A0S1TPL4.1
#=GS A0A1R3TFM9_9ALPH/28-304 AC A0A1R3TFM9.1
#=GS A0A3S8D7G5_9GAMA/193-405 AC A0A3S8D7G5.1
#=GS A0A075CXQ5_9BETA/65-270 AC A0A075CXQ5.1
#=GS Q99D10_BHV4/132-376 AC Q99D10.1
#=GS A0A110A1V9_9ALPH/37-310 AC A0A110A1V9.1
#=GS Q65560_9ALPH/17-306 AC Q65560.1
#=GS J9QVC8_9ALPH/1-206 AC J9QVC8.1
#=GS Q53D36_9GAMA/236-457 AC Q53D36.1
#=GS KITH_EBVA8/291-551 AC Q1HVD1.1
#=GS Q806A6_CHV1/36-311 AC Q806A6.1
#=GS Q9YTP5_ATHV3/216-481 AC Q9YTP5.1
#=GS Q5PPA7_9ALPH/10-278 AC Q5PPA7.1
#=GS M1R9Z0_ELHV1/60-262 AC M1R9Z0.1
#=GS KITH_HHV2H/56-330 AC P89446.1
#=GS A0A2Z5U7A6_9GAMA/305-526 AC A0A2Z5U7A6.1
#=GS A0A1L5JKH4_9ALPH/20-302 AC A0A1L5JKH4.1
#=GS E2IUE7_SHV1/17-302 AC E2IUE7.1
#=GS Q782S2_9ALPH/26-307 AC Q782S2.1
#=GS A0A1V0M8G4_9ALPH/30-312 AC A0A1V0M8G4.1
#=GS KITH_SHV21/216-474 AC P21293.1
#=GS Q86989_ILTV/36-318 AC Q86989.1
#=GS A0A089N6D2_9ALPH/17-306 AC A0A089N6D2.1
#=GS D1FXV9_FHV1/27-304 AC D1FXV9.1
A0A2D1A3F7_9GAMA/418-645 ....GSMGVGKTTLISSVSSMLGS-.DVALAFGEPMDYWRGVF.S-..DCIEKVNKTLK.S.......AASG...GS..GRSA..RSISLLACQTKFLTPLAAIQTAVRRFRHPDDG...-.REVDLSPLDRWCLFDRHPLSAAVIFPLTHAKRGI.LTVEHLFGLLAAFR-A..HRGDVVVLLQG.PPWKNYQRVKGRNRK.AE.DaV.TA..SYLEDMADAYSMFYCT....WLLLQ.......---------------..------------..-...----...-----------------------.-.--------------------------yfapevivelcvgvrhiadacanastrpvqeal............................................
L0N5F5_HHV1/56-329 ....GPHGMGKTTTT-QLLVALGSR.DDIVYVPEPMTYWRVLG.AS..ETIANIYTTQH.R.......LDQG...EI..SAGD..AAVVMTSAQITMGMPYAVTDAVLAPHIGGEA-...-.GSSHAPPPALTLIFDRHPIAALLCYPAARYLMGS.MTPQAVLAFVALIPPT..LPGTNIVLGAL.PEDRHIDRLAKRQRP.GE.R.L.DL..AMLAAIRRVYGLLANT....VRYLQ.......GGGSWREDWGQL---..SGTAVPPQGAEP..Q...SNAG...PRPHIGDTLFTLFRAPELLAPNG.D.LYNVFAWALDVLAKRLRPMHVFILDY.............................................................................
Q6R5W6_9ALPH/26-307 ....GSMGIGKTSMLNEIPTHSLMG.VPVLKVFEPMKYWRYYF.T-..DLVTTVNDTCD.R.......RRRG...EF..SLFQ..SSMIVTALQSKFADPYLVFHERLS----SKCH...R.ITGTRGNPSLILILDRHPISATVCFPIARHLTGD.CSLEMLISMIIRLPQE..PPGCNLVIVDLhDEKEHVSRLSSRNRT.GE.K.T.DL..LMLRALNAVYSCLVDT....IMYANhi..cpySKDEWESEWLDLPWF..DTSLATTFINEP..R...TDYR..gSRVSLHHTLLAIFKRRELCAEDG.S.LSTTHAWILWGLLMKLRNINVERFNI.............................................................................
A0A2D0TCK7_CHV9D/20-297 ....GAFGIGKTTTALAFV--NGSRvNPVFFIGEPMMYWRNMA.GD..DAINGIYGTQV.R.......RKNG...EI..SDND..AQRLTAYFQGLFCSPHSMLHARIL-HLTVQNP...N.NLALKFFNNPVAIFDRHPVASNVCFPISRYVVGD.MTPATLPGFLFAVSEE..PEGTNLIVCTV.SLTNHLTRITNRSRS.GE.I.I.DV..QFILVLRNVYIMLINT....IRYLQ.......AKSDWLIDWFKLPFC..SNSFKQQLQEKE..C...ITIQ...ENPVIENTLFAVFKIPELCDSYG.E.LLDLWKWGMGVLANRLKNISCYVLS-l............................................................................
Q8UZE6_9GAMA/291-546 ....GAPGVGKTTMLNHLKAVF--G.DLTIVVPEPMRYWTHVY.E-..NAIKAMHKNVT.R.......ARQG...R-..--ED..TSAEVLACQMKFTTPFRVLASRKRSLLSTES-...-.GARPVAPLDCWILHDRHLLSASVVFPLM-LLRGQlLSYSDFIQILATFTA-..DPGDTIVWMKL.NGEENLRRLKKRGRK.HE.S.GpDA..GYLKSVNDAYHAVY--....-----.......---------------..------------..-...----...-----------------------.-.--------------------------cawlltqyfapedivkvcaglttittvchqshtpiirsgvaeklyknsifsvlkeviqpfradavllevclaf....
KITH_EHV1B/32-308 ....GVYGIGKSTTGRVMASAASGG.SPTLYFPEPMAYWRTLF.EA..DVISGIYDTQN.R.......KQQG...DL..AADD..AASITAHYQSRFTTPYLILHDHTFGLFGGDS-...-.-LQRGTRPDLTVVFDRHPVASAVCFPAARYLIGD.MSMCALIAMVATLPRE..PQGGNIVVTTL.NVDEHVRRLRTRARI.GE.Q.I.DM..KLIATLRNVYSMLANT....SNFLR.......SGRVWRDGWGELPLS..CETYKHRATQMD..A...FQER...ESPELSDTLFAMFKTPELLDDRG.V.ILEVHAWALDALMLKLRNLSVFCAD-l............................................................................
E9M5K4_9GAMA/267-461 ggia----SGKTTAM-LSAKEEGFS.ENILVVPEAQVFWNEVL.E-..NTCSGLYSVIK.K.......GERG...RA..---T..SA-SLLAHQMAFSIPFRTTREMLD---NCSR-...E.PIYVQNHCNNYVLLDRHLLSPTVIFPFNFFLLRL.MCLQDLVTCMSTFSAT..EMDT-VVLMTV.DAALARARIKRRGRK.AE.EgI.KT..KYLESLNVSINCVHNA....-----.......---------------..------------..-...----...-----------------------.-.--------------------------wsllnflspgtv.................................................................
KITH_HHV11/56-329 ....GPHGMGKTTTT-QLLVALGSR.DDIVYVPEPMTYWRVLG.AS..ETIANIYTTQH.R.......LDQG...EI..SAGD..AAVVMTSAQITMGMPYAVTDAVLAPHIGGEA-...-.GSSHAPPPALTLIFDRHPIAALLCYPAARYLMGS.MTPQAVLAFVALIPPT..LPGTNIVLGAL.PEDRHIDRLAKRQRP.GE.R.L.DL..AMLAAIRRVYGLLANT....VRYLQ.......GGGSWREDWGQL---..SGAAVPPQGAEP..Q...SNAG...PRPHIGDTLFTLFRAPELLAPNG.D.LYNVFAWALDVLAKRLRPMHVFILDY.............................................................................
A0A0B5D5E2_9GAMA/236-465 ....GVMGVGKTTLLNS-MTGVVPQ.ENVLSCPEPMKFWTCVY.S-..NCLKEQRS-IV.K.......QGAG...GK..SIT-..-SARMYACQSKFALPFRATSAGVGRNLQPWL-...-.VGNGGTKPANWIVFDRHLLSATVVFPLVHVKYNR.LAPDHLFQIISLFSAH..D-SDVVVLLTL.SSSEAHRRIQSRGRK.EE.KgI.TQ..NYLRQVAWAYHAVFCT....-----.......---------------..------------..-...----...-----------------------.-.--------------------------wvmmqyltpeqmvqlcvqtvsiedicnmnsrlthrfltltklhe.................................
A0A060CY10_9GAMA/245-491 ....GGMAVGKSTLIQYIQSSLGI-.DTVITFPEPMYYWTEVY.N-..NVLKKIYKANK.H.......WKPA...K-..DSVS..A--ELLSCQLKFAAPLKSMWTYTNRCMNPES-...E.LVPVAP-LDNWVVFDRHMLSACIVFPSLLLNKGM.LSFGDFMHILGTFQA-..TVGDTIVLLTL.GVQENYRRIKRRARK.YE.EfV.DM..HYLKDVRGAFNTAYYA....WLFLQy.....fSIEE-----------..------------..-...----...-----------------------.-.--------------------------vlkvctkvttlkdicsargnvatetalkiwssslfatleeviepfnhsct...........................
KITH_EHV2/301-525 ....GSMGVGKTTLIRHMREI--NG.DNVISFVEPMFYWREVY.S-..DCVKLIYSACK.P.......FNLG...KM..ST--..-SNKVLSAQMKFMTPMKCLQTSVRRYVKANE-...-.PLQEKTAMDNWLLFDRHPLSATLVFPYLSLKNGY.LAFEHFLALAANFTA-..HEGDIIALLCM.GEEDNLKMVKLRNRK.GE.SgV.TS..AHLKDLGQAFHACYC-....-----.......---------------..------------..-...----...-----------------------.-.--------------------------twlllkylspedmvsvcccdvtlndicimrsmssskvtmak....................................
KITH_EBVB9/291-551 ....GAPGVGKTTMLNHLKAVF--G.DLTIVVPEPMRYWTHVY.E-..NAIKAMHKNVT.R.......ARHG...R-..--ED..TSAEVLACQMKFTTPFRVLASRKRSLLVTES-...-.GARSVAPLDCWILHDRHLLSASVVFPLMLLRSQL.LSYSDFIQVLATFTA-..DPGDTIVWMKL.NVEENMRRLKKRGRK.HE.SgL.DA..GYLKSVNDAYHAVYCA....-----.......---------------..------------..-...----...-----------------------.-.--------------------------wlltqyfapedivkvcaglttittvchqshtpiirsgvaeklyknsifsvlkeviqpfradavllevclaftrtla.
U5NIU8_9GAMA/247-471 ....GPMGVGKTTLINTV-CGILPG.ERVVNFPEPMNYWTQVF.T-..DCHRDIYTVIR.T.......GKAG...D-..-PGT..SA-RIYACQCKFALPFRTTGAAVRRMVQPW--...R.VGGEATRGTHWCLSDRHLLSPTVVFPLLHLKLGR.LCFDHFFQLIASFRA-..MEGDIVTIVAL.RSAETLRRLKARGRK.CEgN.V.DQ..DYVREVAWAYHAVYCT....WIMLQ.......---------------..------------..-...----...-----------------------.-.--------------------------yitveqmvqlcvqttnvpeicfrssrlahkedvl...........................................
KITH_HHV8P/260-491 ....GVMGVGKSTLVNAV-CGILPQ.ERVTSFPEPMVYWTRAF.T-..DCYKEISHLMK.S.......GKAG...D-..--PL..TSAKIYSCQNKFSLPFRTNATAILRMMQPWN-...-.VGGGSGRGTHWCVFDRHLLSPAVVFPLMHLKHGR.LSFDHFFQLLSIF-RA..TEGDVVAILTL.SSAESLRRVRARGRK.NDgT.V.EQ..NYIRELAWAYHAVYCS....WIML-.......---------------..------------..-...----...-----------------------.-.--------------------------qyitveqmvqlcvqttnipeicfrsvrlahkeetlknlheqs...................................
A0A1S6JLN8_HSVA1/17-300 ....GPHGAGKSTTARALVALAEAAsRRVAFVEEPMGYWRSAF.SS..DAIFEIYDTQH.R.......LDRK...EI..SPAE..AGAFMTSLQMHMATPYALAEEAFRPHVGREAA...DgAGPQRRDPDATLVVDRHAVASLVCYPMARFLLGC.LSLRSVASLVSLLPPP..LPGTNLVLATL.DRGAHAARLAARARP.GE.R.P.DV..AMLMAIRDVYAMLANT....ARYLR.......RGGDWRRDWPALPVFgrDEFAARAAGEGR..A...IPVR...EDPGLGDTLFAALKVAELLDPRG.R.PRGPHARTLDVLAERIGAMHVSVLDL.............................................................................
A0A3Q8JCB4_9GAMA/177-390 ....GCHGVGKTTMLTNLKSAFD-E.KQLLSFFEPIGFWTSVY.E-..DSLKRVYKATK.Q.......HRLH...K-..-KYA..TSTEVLSCQTKFSVALRTISKSVQGCIQPCA-...-.PLQQMTSEDAMVVFDRHIISSTVIYPLIQMRRGI.LSPCDMLGMFSTFQAN..AYD-VITIVHL.DPDETLCRIRKRGRQ.CE.EgV.DR..QYIMDVNSAYHSVYCT....WLFLR.......---------------..------------..-...----...-----------------------.-.--------------------------ncpieicmrlcldlitmkecaa.......................................................
A0A1P7U0R0_9ALPH/26-307 ....GPLAIGKTSMLNEVPSHSATG.VPVLKVFEPLKYWRRYF.T-..DLVAAVNDASE.R.......RRRG...EL..SLFQ..SSMIVMALQAKFADPFIVLHERIS----SKCH...Q.LAGTRGNPSLILIVDRHPVSATVCFPIARHLIGD.CSLEMLISAITRLPHE..PPGCNLVIAHLpDETEHLKRLSARNRA.GE.T.T.DV..RMLRALNAAYSALADT....VAYANci..cpySKDEWETEWMQLPWF..DASMASTFIDGP..R...SGYH..gSRVSLQHTLLPIFKRKELCSEDG.S.LLTVYGWILWGMLMKLRNINVERLDV.............................................................................
A0A286MM58_9ALPH/16-291 ....GSYGVGKTTAC-RLLAADQWE.ERVVYFPEPMSYWRTMF.GT..DALRGIWSLAT.R.......RRRR...EI..TEAD..AGHLTAYYQSRFAAPYLILHAKTAGEWGSLAA...-.--RGPAERVTTVLFDRHPVAACVCFPFARYVLKE.IDVAELLGLMSTLPAE..PPGTNLIVCSL.TLEEQSARVSARARD.GE.R.Q.HA..PLATTLHNVYTLLVNT....IRFVA.......NGDAWREGWPQLNWS..DDTARAILACPN..T...NQVK...LRPDLADTLFAPLKTAPLCDRDG.A.LFSVHAWALDALAEKLRGINVLTMD-m............................................................................
Q5ZR74_9ALPH/35-316 ....GAYGIGKTTTCKFLAEREAP-.-DYLYFPEPMSYWRKYF.EK..DVITLTYRAQS.E.......HTKR...LV..ASHV..TDVRMGYCQQWFAVPHLTVHRLLS-ALGQHTP...V.RPGAYGERRKVALFDRSIFSAQLIFPLARYAVGH.MSLVSVLNAMGTLPPSdaIPPFNVIVMDL.HAGEVYRRLLTRARK.GE.V.N.DIliPYTVALRNVYRLFLNT....ASYCR......cHRSGWWRDWQIAKHY..RDSALCEDIVST..V...VDVS...HDAAFESTLFQMLKQPETCSESG.A.PKMLIQVLLTDVINLLAKTTVVQ---ldl..........................................................................
A0A068ER26_9ALPH/30-312 ....GAFGVGKTSTLFKLRE-AASG.MQVLHVCEPMRYWRCLF.V-..DVVEEVYDTAA.K.......RRSG...EM..NDRH..ATAIITTAQLQFANPYVVLHDRCTGLFGP---...-.LSGTRGEPDLLVIFDRHPSAACLCFPAARYILQD.ISVEVLITLAANLPRE..SPGGNILVACLdDEEEHLRRLTARARP.GE.K.L.DE..NMLRALRVVYCMLINT....IDFANtqtrrrkSESDWERDWDKLPWF..DEGRRAELLEIG..S...SMER..pEVPCLEKTLLVLFKVPQLCDATG.K.LLRVYAWGLGTMLSKLRGLRIEKLQ-m............................................................................
KITH_GAHVM/26-307 ....GSMGIGKTSMLNEIPTHSLMG.VPVLKVFEPMKYWRYYF.T-..DLVTTVNDTCD.R.......RRRG...EF..SLFQ..SSMIVTALQSKFADPYLVFHERLS----SKCH...R.ITGTRGNPSLILILDRHPISATVCFPIARHLTGD.CSLEMLISMIIRLPQE..PPGCNLVIVDLhDEKEHVSRLSSRNRT.GE.K.T.DL..LMLRALNAVYSCLVDT....IMYANhi..cpySKDEWESEWLDLPWF..DTSLATTFINEP..R...TDYR..gSRVSLHHTLLAIFKRRELCAEDG.S.LSTTHAWILWGLLMKLRNINVERFNI.............................................................................
Q156E1_9ALPH/31-312 ....GPYGTGKTTTGKLLSEDTL--.AATLYVAEPMAYWRNHF.E-..DVIKGVYETQE.R.......KARG...DI..ATTD..AKAITAALQLQFFAPYSSFHTYASTLFGVEA-...-.--PERTPPDITLIIDRHPTAACLCFPAARFVVGD.MSLSTLLAMISLIPRE..PHGGNIVIMDL.NEDEHLERLRARQRP.GE.A.I.DV..RFLRVLHNIYKMFVNT....IWYAKqap.imwDCDKWDKDWSSVPIF..DDDRKKMLEARD..SvpiVGGK...KRPSPSTTLLSLFKVPELCDESF.R.LRKVHEWNLRCALIKLADLNAYFMDI.............................................................................
O41940_MHV68/333-515 ....GGIAVGKTTAL---EAAAEFL.HNILVISEPIPYWTSTF.DK..NVCQQIYDVVK.T.......KEKG...K-..---K..HSKKVLQCQMAFAQPFHATQHLLRR----TCL...G.TKVSDGTCNNYVLIDRHMVSPTVIFPCLFFRLGV.LRFCDLLSLLSVFSAQ..-KFDNVVLFKL.HPKVAATRVKERGRN.PE.GvI.NH..TYLQLLNEVLDA----....-----.......---------------..------------..-...----...-----------------------.-.--------------------------ifcaw........................................................................
Q2QBF4_CHV16/36-311 ....GPHGLGKTTTAAAFAAALRRV.DQIEYVPEPMAYWQTLG.GR..ETIARIFDAQH.R.......LDRG...EI..SAAE..AAMAMASAQVTMSTPYAVTESAVAPHIGPELP...P.GHKPHPSIDLILVFDRHPVAPLVCYPAARYLTGS.LSLPTVLSFAALLPPT..TPGTNLVLGAL.PEAAHVERLAQRQRP.GE.R.L.DL..AMLSAIRRVYAMLGNA....ILYLQ.......TGGSWRADWRRLSPA..RPAA----ESRR..P...ERIL...PHPEIEDTIFALFCAPELLDETG.E.PFRVFAWTLDLLAERLRSMHLFVLDY.............................................................................
A0A0K1R1A9_9ALPH/25-305 ....GPFGIGKTTTCR-MLMIGAPG.QQRLFFPEPMSYWCRYF.NT..DLLKESYTTQD.A.......RTKN...KI..SEEK..CHIATTRYQLWFSAAYQGPDYVLKQSTVGSSI...M.ENPTKGELNHAVLLDRHPLSATMCFPLARHVAGF.MDISGVMNLLTFIPRP..TQYNNLILLDL.DLSEQVYRIKHRNTI.ES.KvI.DT..RYLIILRNIFRLLFNT....ITYCQ......nKPKDWAEEWLEIPLF..HKSPLFRLIGDG..L...VAIN...ESPSIKDTLFQILRQKETITTDG.S.PKLLHQIAIIGMIATLRSFRAIFIN-i............................................................................
A0A077B9Q8_9ALPH/29-306 ....GVYGVGKSTTGRVMASSAGRG.SPTLYFPEPMAYWRTLF.ET..DVIGGIYETQN.R.......KRAG...GL..TGDD..ASLITAHYQSRFATPYLLLHDHTSGLFGSEE-...-.MPRGAAAPDLVLVFDRHPVAATVCFPAARYLLGD.MPMSALLAMAATLPPE..APGANLVVTTL.DVDEHVRRLRARARI.GE.Q.V.DM..QLIATLRNVYAMLVNT....SRFLQ.......SGRVWRDGWGQLPPF..TAARRRHAAQLD..A...YRER...EYPELSDTLFGMFKSPELMDERG.V.LLEVHSWALDALMGRLRHLRVFSAD-l............................................................................
A0A060Q1U8_9ALPH/9-282 ....GPHGLGKTTLAKRLAETLNQS.CETLFVPEPLKYWQSFG.NQ..DAIARVYDTQC.R.......FDQG...EL..PASD..AAMVMTSAQVTMSTPYAALHNLIAPHIGYEI-...-.IDCQAPPTKLALVFDRHPISSLLCYPLARYLVGS.FSLHTVVSMLALLPPA..LPGTNLVLGNL.PRDINAERLMERQRP.GE.I.L.DL..AMLKAIHDVFDRLVNT....IRYVR.......LGHSWLEEWSLLQP-..---LTRTAALVS..E...VKKQ...AHPHIQDTLFALFCAPEMLDCRG.Q.PQLILRWALDILANRALHFELTIVDY.............................................................................
Q3C1Z5_9ALPH/56-330 ....GPHGVGKTTTSAQMMEALGPR.DDIVYVPEPMTYWQVLG.AS..ETLTNIYNTQH.R.......LDRG...EI..SAGE..AAVVMTSAQITMSTPYAATDAVLAPHIGGEA-...-.VGPQAPPPALTLVFDRHPIASLLCYPTARYLMGS.MTPQAVLAFVALIPPT..APGTNLVLGVL.PEAKHADRLAKRQRP.GE.R.L.DL..VMLAAIRRVYDMLANT....VRYLQ.......RGGRWREDWGRL---..TGVAAATTRPEP..K...DSAG...SLPSIEDTLFALFRVPELLAPSG.D.LYHIFAWALDILVDRLRPMHLFVLDY.............................................................................
Q91SC6_9ALPH/12-283 ....GCYGTGKSTAALNFIK-LEKN.NPVYYFPEPMAFWRIIL.ET..DIVQGIYSVQD.R.......KLRG...EL..SLND..ASLITAQLQTKFSTPYILLHSNVSKFFGENV-...-.---TFGIPEVIFIFDRHPIASIVCFPLARYLIGD.MTLESVISIITTLPKE..TPGGNLVITDL.SEDELLQRLKKRSRK.GE.K.I.DL..NLLHALQNVYTMLINT....KRFLE.......-LNDWYKEWDKLPVF..NDCDKNYFLSQF..C...LE-K...DKPSINDTLFRVFKTSSLVKKNR.S.PFIIYKWALEKLVDSLENLKIFKVS-f............................................................................
KITH_VZVD/19-298 ....GAYGIGKTTAAEEFLHHFAITpNRILLIGEPLSYWRNLA.GE..DAICGIYGTQT.R.......RLNG...DV..SPED..AQRLTAHFQSLFCSPHAIMHAKISALMDTSTS...D.LVQVNKEPYKIMLSDRHPIASTICFPLSRYLVGD.MSPAALPGLLFTLPAE..PPGTNLVVCTV.SLPSHLSRVSKRARP.GE.T.V.NL..PFVMVLRNVYIMLINT....IIFLK.......-TNNWHAGWNTLSFC..NDVFKQKLQKSE..C...IKLR...EVPGIEDTLFAVLKLPELCGEFG.N.ILPLWAWGMETLSNCSRSMSPFVLSL.............................................................................
A0A1Z1NEF9_9GAMA/343-603 ....GCMGVGKTSLIR-FLNDSLGW.DDVITFPEPLDFWTNVY.D-..NIVQTVYKAA-.-.......---G...SG..N-AK..ASPTLLSCQLKFAAPLTGIINHLN---RQKHP...A.DTKSITPMDKWLIFDRHPLSPLVVFPLVLLKRGL.LTCQDFISLMSTFKT-..NPYDVIVLLDL.DPEENLHRIKKRGRK.FE.KgI.DA..AYLDDLGQAFHLVYNA....WKLLQy....ftPRD------------..------------..-...----...-----------------------.-.--------------------------avkaclgtvpladvcsdvckdpdraanlqklfnksifsamvkiigpfkgsatllqvcltfayelqqiq.........
G9CUD0_9ALPH/26-307 ....GSMGIGKTSMLNEIPTHSLMG.VPVLKVFEPMKYWRYYF.T-..DLVTTVNDTCD.R.......RRRG...EF..SLFQ..SSMIVTALQSKFADPYLVFHERLS----SKCH...R.ITGTRGNPSLILILDRHPISATVCFPIARHLTGD.CSLEMLISMIIRLPQE..PPGCNLVIVDLhDEKEHVSRLSSRNRT.GE.K.T.DL..LMLRALNAVYSCLVDT....IMYANhi..cpySKDEWESEWLDLPWF..DTSLATTFINEP..R...TDYR..gSRVSLHHTLLAIFKRRELCAEDG.S.LSTTHAWILWGLLMKLRNINVERFNI.............................................................................
A0A0M3T961_9GAMA/194-435 ....GCIGVGKTTLIKYLT-KALND.ENLITFNEAMTYWTQYY.S-..DCVQGIYD-CT.K.......STKK...NL..GSDD..VSHKIFSHQVKFITPLKTLQTSSYNFVFESN-...-.-KFKTKTADNWVIFDRHQLSAAVAFPLAHYLGGF.LKPDHLLGLFSQFTA-..RDGDIIVLMNR.CATDVLGMVKNRGRLyEE.K.V.DI..TYLNILAEAFLLVYNG....WLLLQ.......---------------..------------..-...----...-----------------------.-.--------------------------ffspeelvrvvisgisltdalyckklkdeknqfikdtfnnsvfsilmdii...........................
KITH_PSHV1/11-294 ....GAFGIGKTTVLRQIQKSAAYR.FRRIYLEEPMRAWRSWF.VDdhDAIREIYTTQE.L.......KDAG...EI..DLRE..ASRRVCYAQVSLSAPFHIMNAVIYGIISGESE...A.TSAHLGEGDYFVGVDRHPLASCLCFPVARFVTGY.LEYTDLIALVATLPDY..PRGASIAILDL.SVEEQARRITERSRS.GE.H.V.NK..TFLRILRNVFIIMYNT....VAYLRn.....vSIDKACADREALEDF..RGSQLESDMHKI..D...IQPR...DDPNASETLFAVMASDATWRKNR.K.QSALFVYTMAKLDALLRSLNMHIVDI.............................................................................
A1BM10_9GAMA/252-479 ....GCMAVGKTTLLNYIRRS-SPP.DEVMTIPEPVQYWTQVY.Q-..NVLEEIVRIHK.Q.......WKPG...KL..SSSA..A---LVACQLKFATPLKSQCCYVKHCVQEDA-...-.GRRAVAPLDRWVVCDRHPLSALVVFPLVWLRRGM.LSFGDFLDLLAMF-EA..NVGEVIVLISI.PTDENMIRLQKRGRA.CEqH.I.NL..PYLKEIRGSFHAAYCA....WLFLQ.......---------------..------------..-...----...-----------------------.-.--------------------------yfpvevtmklclqqmtmenacaiskkvsldtaqkmwg........................................
Q98143_HHV8/260-491 ....GVMGVGKSTLVNAV-CGILPQ.ERVTSFPEPMVYWTRAF.T-..DCYKEISHLMK.S.......GKAG...D-..--PL..TSAKIYSCQNKFSLPFRTNATAILRMMQPWN-...-.VGGGSGRGTHWCVFDRHLLSPAVVFPLMHLKHGR.LSFDHFFQLLSIF-RA..TEGDVVAILTL.SSAESLRRVRARGRK.NDgT.V.EQ..NYIRELAWAYHAVYCS....WIML-.......---------------..------------..-...----...-----------------------.-.--------------------------qyitveqmvqlcvqttnipeicfrsvrlahkeetlknlheqs...................................
M4JX30_ELHV1/61-260 ....GCVGVGKTTMFKYVVDNMFVH.T---AYDEPMDHWTNWF.PE..NILQTIHEAVN.-.......----...-L..PTQE..QHAYVFSCQNLIATSFLARESGIV---KTHP-...-.-APFDPSVDVISIADRHALAAYIAFPIHHFLQGR.FTYMELQCMLWAFKQD..SVDTIFLLQG-.CSEETLRRVKRRNRK.VE.HgV.TI..EYINSLQAAYTVILST....W----.......---------------..------------..-...----...-----------------------.-.--------------------------yrateyqysakrtvseeisff........................................................
Q993J7_9GAMA/348-569 ....GVPGVGKTTMLKHLKSVF--G.DLTVVFNEPMAFWTGVY.E-..NTL---KRTSKlL.......KGRG...GQ..TSGS..ADL--LSCQMKFATPFRVAAARKRTFYSSEN-...-.GPRPVAPLDCWILHDRHLIAATVVFPLLHLKNKL.LSFSDFIQLLSTFNAE..-DGETIVWLKL.NMAENLRRIKKRGRR.YE.A.S.NE..EYLKRVNWAYHAVY--....-----.......---------------..------------..-...----...-----------------------.-.--------------------------cawlltqyftpedivrvcagittistvchhsptpiirssva....................................
KITH_ALHV1/245-480 ....GCMAAGKTTLL-NFARQTLSD.DEALTIPEPMRFWTEVY.T-..NVLSQIVKINK.E.......CKPG...KT..STT-..AE--LVSCQLKFATPLKTQSLFLQRSVKKDS-...-.EMQPVGPLDKWVIVDRHQLSALVVFPLVLMRRGM.LSFSDFFNLLG-MFEA..HPGEVIALMSV.NVEENFTRLKKRGRV.CErH.I.DR..DYIKEIKGSFNAAYCA....WLFLQy.....fSI-------------..------------..-...----...-----------------------.-.--------------------------qttmqicmglssldeacategvchttasriwnnsmlvtlsd....................................
Q77L27_MEHV1/17-299 ....GPFGIGKTSILNAMPDHTPDG.APILKVYEPMKYWRCQS.T-..DLVVAANETPE.R.......RRGG...AL..SRFQ..SDMIMASIQARFADPYLLFHERLS----SKCR...G.KIEICDTPAIILMLDRHPVAAILCFPITRYLLGE.YSLEMLISSIIRLPLE..SPGCNLTVTILpDEKEHVNRICSRDRP.GE.T.A.DR..NMLRTLNAVYASLVDT....VKYANlt..cpyEKESWEMEWLGLPWF..EESLLEEFISRP..Rp.vICSR...TRMPLDRTLLAIFKRKELCSENG.E.LLTQYSWILWGLLTKLHTINVELFDI.............................................................................
A0A0S1TPL4_9BETA/55-256 ....GCIGVGKTSLFK-YAADNLP-.NLCTLYDEPMLHWTEWF.PE..NVLETLYSSLT.L.......PND-...--..--ED..RQIRLFACQNMIATPFLAREAGCV------RK...Y.PAPYDPGFDTLSIADRHPSAPFIVFPLHQYLHGN.FSYIGLYSMLWSFRQE..YVDTIVVLLG-.EPEETLRRVRQRNRS.VE.SgV.TL..EYIKSIQTSYNIFLNT....CRLA-.......---------------..------------..-...----...-----------------------.-.--------------------------sdyippspssssagkrgd...........................................................
A0A1R3TFM9_9ALPH/28-304 ....GAYGIGKSTCASVMTESVLY-.-PTLYAREPMAYWRRFFfPS..DIVSDVYSTQE.R.......RRTG...KI..SEED..ADAVTTSLQVRFASPYLTLHAATRALFGQET-...-.--YTQQRPDITLIFDRHPIAAILCFPAARYVVGD.MSIEAFLALISTLPED..SSGANIVVADI.TEEEHVRRLQGRNRR.GE.K.I.DM..NLLRALRNIYIMLINT....ISYARl.....rSQVSWRDDWDSIPTF..DDTVRDRITSQR..S...YFIS...EPPQLRFSLLTLLKTPVICDGDG.F.VRRIHELAIDNLMNKLALLHVYYA--df...........................................................................
A0A3S8D7G5_9GAMA/193-405 ....GCHGVGKTTLVNRLASSF-PE.KQLLTFLEPLGFWSMVY.E-..DSLKKIYKA-T.R.......QHKP...YK..KKYD..ASNEVLSCQTKFSVALRTIARSVQECMQPCA-...-.PLQQVTSADAMVIFDRHLISSTVIYPLVQMKKGI.MSPCDMLGMFSGFRAN..TFD-VIVLIIL.DADETLRRIRKRGRS.CE.DgV.DR..QCIIDVSSAYHTVYCT....WLFVR.......---------------..------------..-...----...-----------------------.-.--------------------------ycpielcmklclelitmnec.........................................................
A0A075CXQ5_9BETA/65-270 ....GCLGVGKTSLFKYIVNNMFVH.T---AYDEPMDYWTTFF.SE..NVLKTIHEAVD.-.......----...-L..PKPE..QHRHIFSCQNLMAAPFLSREYGIT-----KT-...H.PAPFDPSSDVISIADRHVMAAYLVFPLHHFLQGR.FTYMELFSMMWAFNQK..TVDTIFLLQG-.CSEETLRRVRHRNRK.VEqR.V.TI..EYINSLQAAYTVILST....WYRAQ.......-EYRDRGDRE-----..------------..-...----...-----------------------.-.--------------------------qrrdistqisffia...............................................................
Q99D10_BHV4/132-376 ....GVMGVGKTTLLKTLARN--DM.NNVIIFEEAMNYWKTVF.S-..DCHKLIYDVMK.M.......GKHG...SF..SVS-..--SKLLACQMKFLTPLKSLGRVT-AMFSGKEM...Q.RSPGRSDVSHWVMFDRHALSACLVFPLVMLKSGM.LSFEHFISLVSTFRA-..NEGDIIVLIAL.DHGEAIRRIKTRKRP.EEeT.I.SL..TYVIRLHWCFVAVYNT....WRLLQy.....fTAREATEVCLDIKTI..NGLCLSKDI---..-...----...-----------------------.-.--------------------------cyqkclefqtlwnesllailrdiifpyk.................................................
A0A110A1V9_9ALPH/37-310 ....GPHGIGKTTLGSSLAKTLSPH.TSTVFVPEPMAYWRAVG.GV..DAIANVYETQR.R.......RDNN...EI..SVDE..ASLIMTNTQLLMNTPYMALDQQMEPLLGWGAS...P.L--PPPRPTQTIIVDRHPIASLVCYPLARYLMGS.FNIQTAMTFLSFIPKI..PPGTNLVLGKL.PGGETAQRLYERSRP.GE.V.M.DW..HMIGCIHNIYDRLQNT....ISYIQ.......QGHNWRDEWHTL---..-VPMTAMDIRFE..P...VSGC...ETPCIRDTLFAVFCTPALAQPTG.R.LSNVHAAVFDILSDRLGRFNMFVLDY.............................................................................
Q65560_9ALPH/17-306 ....GAHGLGKTTTGRALAAASTAG.EGVLFFPEPMAYWRTMF.GT..DALSGILAASA.RcaaashgSARGaggPAhrADAD..AAGLVAYYQARFAAPYLILHARVSALLAPPG-...-.---PAPGGTVTLVFDRHPVAACLCYPFARYCLRE.INAEDLLMLAAAMPPE..APGANLVVCTL.PPAEQQRRLAARARP.GD.R.A.DA..GFLVAVRNAYALLVNT....CAFLR.......AGGAWRDGWDALEWA..DANALAALADPS..C...DECKm.aPAPALRDTLFAALKCRELYPGGG.TgLPAVHAWALDALAGRLAALEVFVLDV.............................................................................
J9QVC8_9ALPH/1-206 ....----MGKTTVARALAGALGEA.YEVFYLPEPMRYWRGAG.EN..DLVSRVYDTQR.R.......VDRG...EI..NARE..AADIIVGTQLLMSTPYVTLDRVIAPHLGDEI-...-.GHNDATPPGLVLIFDRHPIAALLCYPVARYLVGC.LSIDAVIALIALMPPI..APGTNLVMGAV.PEETHLARLAGRGRR.GE.S.T.DV..RMLLAIRRTYDLLLNT....VRYLR.......CGGRWREDA------..------------..-...----...-----------------------.-.--------------------------rkgae........................................................................
Q53D36_9GAMA/236-457 ....GVMGVGKTTLLNS-MTGMVPQ.ENVLSCPEPMKFWTCVY.S-..NCLKE---QRS.I.......VKQG...TH..GKSI..TSARVYACQSKFALPFRATAAGIGRNLQPWL-...-.VGNGSTKPANWIVFDRHLLSATVVFPLVHVKYNR.LTPDHLFQILSL-FSA..HDGDVVVLLTL.NSSEAHRRIQSRGRK.EE.KgI.TQ..NYLRQVAWAYHAVFCT....-----.......---------------..------------..-...----...-----------------------.-.--------------------------wvmmqyltpeqmvqlcvqtvsiedicnmnsrlthrf.........................................
KITH_EBVA8/291-551 ....GAPGVGKTTMLNHLKAVF--G.DLTIVVPEPMRYWTHVY.E-..NAIKAMHKNVT.R.......ARHG...R-..--ED..TSAEVLACQMKFTTPFRVLASRKRSLLVTES-...-.GARSVAPLDCWILHDRHLLSASVVFPLMLLRSQL.LSYSDFIQVLATFTA-..DPGDTIVWMKL.NVEENMRRLKKRGRK.HE.SgL.DA..GYLKSVNDAYHAVYCA....-----.......---------------..------------..-...----...-----------------------.-.--------------------------wlltqyfapedivkvcaglttittvchqshtpiirsgvaeklyknsifsvlkeviqpfradavllevclaftrtla.
Q806A6_CHV1/36-311 ....GPHGLGKTTTAAALAAALGRR.DEIEYVPEPMAYWQTLG.GP..QTITRIFDAQH.R.......LDRG...EI..SAGE..AAVAMASAQVTMSTPYAVTESAVAPHIGAELP...P.GHGPHPNIDLTLVFDRHPVAPLLCYPAARYLMGS.LSLPTVLSFAALLPQT..TPGTNLVLGAL.PEAVHAERLAQRQRP.GE.R.L.DL..AMLSAIRRVYDMLGNA....IVYLQ.......QGGSWRADWRRLSPA..RPAAAS----GR..P...ARIL...PRPEIEDTIFALFCAPELLDGTG.E.PYRVFAWTLDLLAERLRPMHLLVLDY.............................................................................
Q9YTP5_ATHV3/216-481 ....GSIGVGKTTLLK-SMRGILPG.KNVLTFHEPMAFWKNVF.S-..NSLDEVYKLTL.P.......AKVG...SM..--TN..SSKL-LACQLKFAAPLLALKTSTDRLSISN--...-.--RSNLSSNMWVMFDRHPLSATVVFPYMHYQNGF.LSFSHLVHLWGSFR-A..SHGDNIILLNL.NSQENLERVKRRNRK.EE.KcV.SL..EHIRMLNSCYHAVYCA....WLLVQ.......--NFTPEEIVEV-CF..NTKQITDLRSSK..P...SFLE...KHVSIEDVL--------------.-.--------------------------kssifnawmdmtkayrdnctlmeclltlckelekvqllhi.....................................
Q5PPA7_9ALPH/10-278 ....GAYGTGKSTTARVM-----AL.GGALYVPEPMAYWRTLF.DT..DTVAGIYDAQT.R.......KQNG...SL..SEED..AALVTAQHQAAFATPYLLLHTRLVPLFGPAV-...-.----EGPPEMTVVFDRHPVAATVCFPLARFIVGD.ISAAAFVGLAATLPGE..PPGGNLVVASL.DPDEHLRRLRARARA.GE.H.V.DA..RLLTALRNVYAMLVNT....SRYLS.......SGRRWRDDWGRAPRF..DQTTRDCLALNE..L...CRPR...DDPELQDTLFGAYKAPELCDRRG.R.PLEVHAWAMDALVAKLLPLRVSTVDL.............................................................................
M1R9Z0_ELHV1/60-262 ....GCVGVGKTTMFKYVVNNMFVH.T---AYDEPMDHWTKWF.PE..NVLQTIHEAVN.-.......----...-L..PTQE..QHTHVFSCQNLIATSFLARESGIV---KTHP-...-.-APFDPSVDVISIADRHALAAYVAFPIHHFLQGR.FTYMELQCMLWAFKQD..SIDTIFLLQG-.CSEETLRRVRNRNRK.VE.QtV.TI..EYINSLQAAYTVILSTwyraTEYLE.......SE-------------..------------..-...----...-----------------------.-.--------------------------kksvaeeisffiag...............................................................
KITH_HHV2H/56-330 ....GPHGVGKTTTSAQLMEALGPR.DNIVYVPEPMTYWQVLG.AS..ETLTNIYNTQH.R.......LDRG...EI..SAGE..AAVVMTSAQITMSTPYAATDAVLAPHIGGEA-...-.VGPQAPPPALTLVFDRHPIASLLCYPAARYLMGS.MTPQAVLAFVALMPPT..APGTNLVLGVL.PEAEHADRLARRQRP.GE.R.L.DL..AMLSAIRRVYDLLANT....VRYLQ.......RGGRWREDWGRL---..TGVAAATPRPDP..E...DGAG...SLPRIEDTLFALFRVPELLAPNG.D.LYHIFAWVLDVLADRLLPMHLFVLDY.............................................................................
A0A2Z5U7A6_9GAMA/305-526 ....GSMGIGKTSLIKHLREV--SG.DNVISFTEPMVYWREVY.D-..DCVKSIYKCCR.P.......SNVG...--..-KKT..TSSKILSTQMKFMTPLKCLQTSTRRFLKTGE-...-.PLQHKVPGDNWVIFDRHIMSPTLVFPLVFLKNGY.LSFEHFMSIVSNFRA-..HEGDIIGLLCM.ADEDNLKMIKKRNRK.GE.EgV.SS..SYLKDVSQAFH-----....-----.......---------------..------------..-...----...-----------------------.-.--------------------------scyctwlllryfspedmvsvcccdvtlselcimksmsnekhe...................................
A0A1L5JKH4_9ALPH/20-302 ....GAHGLGKTTTGRALAAAASAAgGPVLFFPEPMAYWRTMF.PT..DALSGILAASA.R.......PPGA...AP..RRADaaAAGLVAYYQARFAAPYLVLHARVAALLAPPE-...-.-PVPGGDDVVTLVFDRHPLAACLCYPFARYCLRE.INAEDLLALAAAAPPE..APGANLVVCTL.PPAEQRRRLAARARP.GD.R.A.DA..GFLAAVRNAYTLLVNT....CAFLR.......AGGAWRDGWDALGWA..DADALAAL-ADP..R...GGGRepaPAPALRDTLFAALKCRELYPGGGaD.LPAVHAWALDALADRLAALEVFVLDV.............................................................................
E2IUE7_SHV1/17-302 ....GPHGVGKSTTAEALVARCEAEaADTVYLQEPMAYWRSTF.AS..DAITEIYDTQH.R.......LDSN...EI..TAAE..AGAFMTSLQLHMGTPYALLEEAMRPHVGRELAepdD.NGPLPQRRDFVLVVDRHAVASMVCYPLARFMMGC.VSLRSVASLISHLPPP..LPGTNLVVASL.DFREHAARLRARARP.GE.R.L.DL..TMMAAIRNAYAMLANT....SRYLL.......SGGDWRRDWGSLPVF..KPSAFVARAAKTayT...LPLR...DEPGLADTLFAALKVPEFLDARG.Y.PRAAHAWTLDILANRIRALRVYTLDL.............................................................................
Q782S2_9ALPH/26-307 ....GPLAIGKTSMLNEVPSHSATG.VPVLKVFEPLKYWRRYF.T-..DLVAAVNDASE.R.......RRRG...EL..SLFQ..SSMIVMALQAKFADPFIVLHERIS----SKCH...Q.LAGTRGNPSLILIVDRHPVSATVCFPIARHLIGD.CSLEMLISAITRLPHE..PPGCNLVIAHLpDETEHLKRLSARNRA.GE.T.T.DV..RMLRALNAAYSALADT....VAYANci..cpySKDEWETEWMQLPWF..DASMASTFIDGP..R...SGYH..gSRVSLQHTLLPIFKRKELCSEDG.S.LLTVYGWILWGMLMKLRNINVERLDV.............................................................................
A0A1V0M8G4_9ALPH/30-312 ....GAFGVGKTSTLFKLRE-AASG.MQVLHVCEPMRYWRCLF.V-..DVVEEVYDTAA.K.......RRSG...EM..NDRH..ATAIITTAQLQFANPYVVLHDRCTGLFGP---...-.LSGTRGEPDLLVIFDRHPSAACLCFPAARYILQD.ISVEVLITLAANLPRE..SPGGNILVACLdDEEEHLRRLTARARP.GE.K.L.DE..NMLRALRVVYCMLINT....IDFANtqtrrrkSESDWERDWDKLPWF..DEGRRAELLEIG..S...SMER..pEVPCLEKTLLVLFKVPQLCDATG.K.LLRVYAWGLGTMLSKLRGLRIEKLQ-m............................................................................
KITH_SHV21/216-474 ....GSIGVGKTTLLKSM-NGILGG.KNVLAFHEPIAYWTDVF.S-..NSLEEVYKLTL.P.......AKVG...RT..SN--..-SAKLLACQLKFASPLLALKTATDRLSSPK--...-.--NSLLSSDMWVMFDRHPLSATVVFPYMHFQNGF.LSFSHLIQLWSSF-KA..SRGDNIILLNL.NSQENLKRVKKRNRK.EE.KsV.SI..EHIRLLNNCYHAVYC-....-----.......---------------..------------..-...----...-----------------------.-.--------------------------awllvqnftpeeivevcfnakhitdlssskpsflakhvstedmlkssifntwiemtkahrdsctlmeclltfckele
Q86989_ILTV/36-318 ....GPFGVGKTVTAKTLMQMPNWR.GCRLYLAEPMQAWRQWF.GG.aDMIKEINEIQT.L.......KASG...KL..ECRE..ASRRVAEVQMTIAAPLRIMNHVIYNYLGSERC...Y.SAAASGPDDVLFLVDRHPLAACLCFPVAQYLSGA.LEFGDLITLLSGIPDI..PTHSNIVLMDL.DICEQARRIIQRGRP.GE.T.V.DW..TYLCALRNSYICLMNT....TTYLQr.....tSYPALLKEQEALTSA..TLLKFKRECLET..A...TVPE...INPSIDQTLFAILAFDQQNVHGE.R.LKTVLSFVVQKLATVLKNLCIFYL--pa...........................................................................
A0A089N6D2_9ALPH/17-306 ....GAHGLGKTTTGRALAAASTAG.EGVLFFPEPMAYWRTMF.VT..DALSGILAASA.RcaaashgSARGaggPAhrADAD..AAGLVAYYQARFAAPYLILHARVSALLAPPG-...-.---PVPGGTVTLVFDRHPVAACLCYPFARYCLRE.INAEDLLMLAAAMPPE..APGANLVVCTL.PPAEQQRRLAARARP.GD.R.A.DA..GFLVAVRNAYALLVNT....CAFLR.......AGGAWRDGWDALEWA..DANALAALADPS..C...DECKm.aPAPALRDTLFAALKCRELYPGGG.AgLPAVHAWALDALAGRLAALEVFVLDV.............................................................................
D1FXV9_FHV1/27-304 ....GAYGIGKSLTAKYLVRADENRpGYTYYFPEPMLYWRSLF.ET..DVVGGIYAVQD.R.......KRRG...EL..SAED..AAYITAHYQARFAAPYLLLHSRLST-ITGYQ-...-.KVVCEEHPDVTLIIDRHPLASLVCFPLARYFVGD.MTLGSVLSLMATLPRE..PPGGNLVVTTL.NIEEHLKRLRGRSRT.GE.Q.I.DM..KLIHALRNVYMMLVHT....KKFLT.......KNTSWRDGWGKLKIF..SHYERNRLVETT..I...VSDS...TESDLCDTLFSVFKARELSDQNG.D.LLDMHAWVLDGLMETLQNLQIFTLNL.............................................................................
#=GC seq_cons ....GshGlGKTThhptlhsshhst.stllhhsEPMsYWppha.s...Dslpplacspp.+.......tcpG...ch..sttc..uuhhhhusQh+FusPahshcstlp.hhtsps.......htstsssshhllaDRHPluAslsFPls+ahhGp.hohpslluhluthstt..ssGsslVlhsL.stpEplcRlppRsRt.uE.p.l.Dh..shLpslpssYphlhsT....hhahp..................................................................................................................................................................................
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