#=GF ID   Herpes_U5
#=GF AC   PF05999.15
#=GF DE   Herpesvirus U5-like family
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF SE   Pfam-B_8027 (release 9.0)
#=GF GA   25.00 25.00;
#=GF TC   26.70 32.70;
#=GF NC   23.30 21.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF DR   INTERPRO; IPR010302;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family of Herpesvirus includes U4, U5 and UL27.
#=GF SQ   26
#=GS I3VQ05_9BETA/59-329        AC I3VQ05.1
#=GS G8XUA2_9BETA/138-569       AC G8XUA2.1
#=GS A0A0K1H091_9BETA/142-572   AC A0A0K1H091.1
#=GS Q7TFT5_RHCM6/144-574       AC Q7TFT5.1
#=GS G8XTT4_SCMVC/140-564       AC G8XTT4.1
#=GS VU5_HHV6U/2-425            AC Q01352.2
#=GS A0A0G2UPG0_9BETA/140-565   AC A0A0G2UPG0.1
#=GS Q91TS2_TUHV1/141-536       AC Q91TS2.1
#=GS G8XSU1_9BETA/136-266       AC G8XSU1.1
#=GS Q8QS61_9BETA/165-635       AC Q8QS61.1
#=GS I3WF54_9BETA/144-574       AC I3WF54.1
#=GS A0A0F7GA43_SCMVC/151-579   AC A0A0F7GA43.1
#=GS G8XSU1_9BETA/263-492       AC G8XSU1.1
#=GS UL27_HCMVA/163-603         AC P16763.1
#=GS UL27_HCMVM/163-603         AC Q6SWA4.1
#=GS H2A336_MUHV1/156-448       AC H2A336.1
#=GS U6H6M3_9BETA/151-528       AC U6H6M3.1
#=GS Q9DWG2_RCMVM/88-381        AC Q9DWG2.1
#=GS A0A1L6Z0S2_9BETA/142-572   AC A0A1L6Z0S2.1
#=GS A0A1P8VIS1_9BETA/50-410    AC A0A1P8VIS1.1
#=GS I3VPZ5_9BETA/167-558       AC I3VPZ5.1
#=GS K7Y9Z1_RCMVE/155-551       AC K7Y9Z1.1
#=GS E9RH41_9BETA/151-529       AC E9RH41.1
#=GS VU7_HHV6Z/462-885          AC Q9QJ54.1
#=GS A0A192XNI0_9BETA/787-1209  AC A0A192XNI0.1
#=GS VU5_HHV7J/425-846          AC P52522.1
I3VQ05_9BETA/59-329                   ......IRNASFFSDADQETVSLAKIFCIGHYVKAYYAQYRGKrNTLIGYIRDLCKMANSMFCRLI..-.VLR-Y.MG..ERR...N..NANMRAVFDVLK-.--NPIDD-ETYGA.VAYSNDALYESYRVNLNYVSKILCNCAEC..Q.D-NIVS.RPLGRVLCVG-NPRPRMA--D.RGRGRSW...LGDKTVHLKGSASFPPMCLPDIGHLSDAQISVILEELSNDVMQ.--.-.--RH..VYSVMDAGQLPLRLDTT..SMGRdfmERN....TIMLIYNVTFTLFLLSSVRKLIRLELDLLKCAFVEEVSNL-------------.---.............----.............-------.-.-----------....-------------------------...-----------------------------------.....---.......-----..-----...-----------------------------------------------------------------------------------------------------rgcvann..............................................
G8XUA2_9BETA/138-569                  ....ls--QARFLPNVSRVAKRLCLAMATAQHVVWSLLNYKCC.GTITHFLRQMCSLTVDIYDKLY..D.TLALF.QD..DDT...K..IAIQQFFINRLCE.-GAGLD-YHGHRH.AVFFKLEFRRAAERALALMYRQLCGCEEC..G.G-----.--TTAASNAG--PDSEQRPNV.HA--WPR...LESVAISLSNYPDLGRFHLPALRHLKAAEQTRLRDAVSRDLGF.SL.W.NHNG..FE---PRFLLPQELRGT..--TD...KSY....VLFLVSNIVFNLKIIWILRQIVQREFADAVQFLAFDRDILIGYLHRRHALFQE.GLV.............QSEA.............HRQLVAD.CqRYLADLRDIDF....ANFERRTFVESLCAFMDLAEQIPDY...RQLSLIDKQRQFLLHNFRIRC--------------.....---.......-LYET..PSPET...RLGESLCWYYLKRGDVPLGKEALLK-----IN------------TRLSDAELCNDANRCRRRTWLDL-PIVTVLPVKRHMQMA---RYTNVYVRRFQH---gev..................................................
A0A0K1H091_9BETA/142-572              ..vaag----PFLPEISKSGKRIALAVATGQYAVSTLLNYKVF.GNKTHYLRQLCVITEELFRRLA..G.TVCLF.LD..AGD...R..DLIQKCLPSHLCK.-KLPVN-YRVQKN.AVFFNSRFGLRAEAALHTLYARFCTCGDC..H.DLFAAS.SDTQATP-------SEDEPS-.--PPQPR...LEDAELTLLHNAHLGKFHLPAIRHLTAAEQLRVQQSVARDLGF.TD.W.SHTL..VD---DYFLLPVGLSCG..-TPC...EGY....AMYLMSNAVLALKVIRLLYITIRHEHSACVRALCKDVAFLIRMFRYEASIIRK.GLA.............QNAA.............QRMELSR.F.R--RHIHDLKH....IHFTVSNFLETFCDFIKIVNKIPDY...QCISLTIKRELVLLHLLRLRR--------------.....---.......-VYEC..PSAET...RKGEKLAWYYFRHGDVTLDPGILMT-----------------FDSLLADCELSNNANRCRRKAPFEIPT----SATVTVRYQGHIEKLHRLYVRRFRPHEV.....................................................
Q7TFT5_RHCM6/144-574                  ..vaag----PFLPEISKSGKRIALAVATGQYAVSTLLNYKVF.GNKTHYLRQLCVITEELFRRLA..G.TVCLF.LD..AGD...R..DLIQKCLPPHLCK.-KLPVN-YRVQKN.AVFFNPRFALRAEAALHTLYARFCTCGDC..H.DLFVAS.SDTQATP-------SEEEPS-.--PPQPR...LEDAELTLLHNAHLGKFHLPAIRHLTAAEQLRVQQSVARDLGF.TD.W.SHTL..VD---DYFLLPVGLSCG..-TPC...EGY....AMYLMSNAVLALKVIRLLYITIRHEHSACVRALCKDVAFLIRMFRYEASIIRK.GLA.............QNAT.............QRMELSR.F.R--RHIHDLKH....IHFTVSNFLETFCDFIKIVNKIPDY...QCISLTIKRELVLLHLLRLRR--------------.....---.......-VYEC..PSAET...RKGEKLAWYYFRHGDVTLDPGLLMT-----------------FDSLLADCELSNNANRCRRKAPFEIPT----SATVTVRYQGHIEKLHRLYVRRFRPHEV.....................................................
G8XTT4_SCMVC/140-564                  ..vaag----PFLPEISKSAKRIALAVATGQYAVCTLLNYKVF.GSKTHYLRQLCVITDELFRRLA..G.TMCLF.LN..PDD...R..DLIEKCLPLSICK.-KLSLD-YRAQKN.AVFFHPRFSARAEEALKELYARFCNCGDC..H.D-----.---TPLPDVL--------DSS.QEEPRPR...LEDVELRLLNNAQLGRFRLPAIRHLTASEQLRVQQNVARDFGF.TY.W.SNTL..VD---DYFLLPVGSSCG..-TPC...EGY....VMYIMSNAVLALRVIRLLYISIRHEQDACARALSKDVQCLIKMFRYEASVIRK.GLA.............QNAA.............QRMELSR.F.R--RHVHDLKQ....ISFNVDNFVETLCDFIKIVNKIPDY...QCISLNIKRELVLLHLLRLRR--------------.....---.......-VYES..PSPET...TKGEKLAWYYFRHGDVALDPGLLMT-----------------FNSILADCELSNNANRCRRKVPFEIPATA----RVTIRYQGHLDKLHRLHVRRFRPHEV.....................................................
VU5_HHV6U/2-425                       ......VKDLKFMDNFNEKWQCITKLAFLGLYAGASLFNFTSK.PTLGYWCRYLSEYASMLLFQFE..S.KLKEL.TK..EST...R..QLGG----YNLCH.WGQELKDCLENKS.DVFFRYDFFERIESCLIEHFMLLCGCVEC..R.RMFIMY.NKRGRKFDFG-----------.---HSVR...IQCFPM-------IGSIRLPAFLHLGEPYDVSLSSLIAKDLGL.--.-.--SM..IEGQIELSRLPISLQIS..VTPD...KKA....LLTFLTNIVFIVFVVNTLYRVINAELDIYYDLFTEEVGKLCVAMEEEMKLGRN.GCL.............----.............--GDLCY.F.SPMKQMKEIVR....CPGEKSQFILKCWEALRIGFSVPAY...KDYDETPFMEMFFMHHLHIKRFHEDNDRDLVSCDN.....LIP.......GFFIV..NTDGE...NFLQRL------------QRVVLPVVEDYLTNTRCINGTMAFFFSGLKYFGSGNHR-------------GFQISPEKDVRAIAY--KLGSLDVLR-DDYKY.....................................................
A0A0G2UPG0_9BETA/140-565              .vgagp-----FLPEISKSAKRIAVAVATGQYAVCTLLNYKVF.GTKTHYVRQLCVLTDELFRRLS..G.TMCLF.LN..PDE...R..ELIDKCSPLSICK.-KLSLN-YRAQKN.AVFFHPRFHVRAEEALKALYAKFCTCGDC..H.ESSCLT.NG---------------SDAA.AEPLRPR...LEDAELRLLNNTQLGRFHLPAIRHLSAAEQLRVQQSVARDLGF.TD.W.SNTL..VD---DYFLLPVGMSCG..-TPC...QGY....AMYLMSNAVLALKVIRLLYITVRHEQNACVRALCKDVNCLIKMFRCESFSIRK.GLA.............QNAA.............QRMEVSR.F.R--RHVQDLKQ....IKFTVETFVETFCEFIKIVNKIPDY...QYISIHVKRELVLLHLLKLRR--------------.....---.......-VYES..SSPET...RRAERLAWYYLRHGDVTLDPGLLMT-----------------FNSILADCELSNNANRCRRKAPLVIP----ATATVTVRYQGHLEKLSRLHVRRFRPHEV.....................................................
Q91TS2_TUHV1/141-536                  ...lnt---VAFRPEASDVARHVARTVAVGQYAVQTVFDYRNP.GGLSHYLRFLCESVHALYGRLE..-.RIGDT.LD..DRA...R..LLIADLLPRAVCR.-QLGYA-YDPDDQ.TFIFDPQYLHASEQVLQILYDRLCDCEEC..Q.ERRFTA.AAAATSLRRG--PKR-----R.KRSSWAA...FERRDVVLEQYRELGVLRLPCLRHLKRDQQLELCQQLRHDLCF.-R.R.RQTL..TA---RELLLPIGVPCG..HGVS...DAY....ALYLASNLVFTLFLAQTLHAIVRIEARAYIDLLSGHADALVGALRRQASYLQH.GGLgdgdgndagpsggRSPS.............DGRKLAR.L.T--RRLRGLDFgfggGSGSGTAFFTAFCDFLEIVEKLPDY...ARLSEFQVREELLVHHFYLAQVY------------.....---.......-----..-----...-----------------------------------------------------------------------------------------------------adpspetqagerlvsyyvqngdaccqdaarlra....................
G8XSU1_9BETA/136-266                  .....l-QQAQFLPHTSRFARTACISMATAQYLMCTLINYKEC.GSLTHYMRQLCSMTGEIYDRLA..G.TLPLF.DD..PET...K..NVIRKFFIDDLCQ.-EAGL-DYRVLRN.AVFFKTEFQQACERALAALYAHLCICGDC..N.E-----.---------------------.-------...-------------------------------------------.--.-.----..-----------------..----...---....-----------------------------------------------------.---.............----.............-------.-.-----------....-------------------------...-----------------------------------.....---.......-----..-----...-----------------------------------------------------------------------------------------------------tvepn................................................
Q8QS61_9BETA/165-635                  ......VHRARYLPEISRAAKRMALAVATGQYVVCSLLDYKSF.GTRTNYLRQLCTLTEELYMRLD..G.TMCLF.LD..PEE...R..EVIARCLPQFLCR.-GLAVR-YRSHRA.AVFFNATFGARAETALKRLYSAFCECGDW..R.DPDVPV.EAAEAVAAA--SQHAHMLP--.--PPHFH...LENAELRLENNRHLGAFHLPAIRHLTVDDISRIRASVSRDLGF.AE.W.SQTL..VD---DYFLLPTGWACA..-NPR...RGY....VMYLASNAVLALRIIRLLHASIRHEQTACVRMLSGDVQRLIRLFKGEAAMLRK.GLA.............QNPV.............QRRELSR.F.R--KHVHDLKR....VRFTVDGFVESFCDFLDVIHRIPDY...RCISLRIKRELLCLHTFKLRRVYRPPPSSLLAGSHhnnsvVLPpptttnaSSPAPssPHPDPqllLRAERLAWHYLRHGDVPQDRSRLPQ-----------------FSSALSDAELSNNANRCRRKAPVEFAG---FAGGPSVRYRAHIQRFDRLYVRRFRPHEV.....................................................
I3WF54_9BETA/144-574                  ..vaag----PFLPEISKSGKRIALAVATGQYAVSTLLNYKVF.GNKTHYLRQLCVITEELFRRLA..G.TVCLF.LD..AGD...R..DLIQKCLPPHLCK.-KLPVN-YRVQKN.AVFFNPRFALRAEAALHTLYARFCTCGDC..H.DLFVAS.SDTQATP-------SEEEPS-.--PPQPR...LEDAELTLLHNAHLGKFHLPAIRHLTAAEQLRVQQSVARDLGF.TD.W.SHTL..VD---DYFLLPVGLSCG..-TPC...EGY....AMYLMSNAVLALKVIRLLYITIRHEHSACVRALCKDVAFLIRMFRYEASIIRK.GLA.............QNAT.............QRMELSR.F.R--RHIHDLKH....IHFTVSNFLETFCDFIKIVNKIPDY...QCISLTIKRELVLLHLLRLRR--------------.....---.......-VYEC..PSAET...RKGEKLAWYYFRHGDVTLDPGLLMT-----------------FDSLLADCELSNNANRCRRKAPFEIPT----SATVTVRYQGHIEKLHRLYVRRFRPHEV.....................................................
A0A0F7GA43_SCMVC/151-579              ..vaag----PFLPEISRSAKRIAVAVATGQYAVCTLLNYKVF.GTKTHYVRQLCVLTDELFRRLS..G.TMCLF.LN..PDE...R..ELIDRCSPVSLCK.-KLSLN-YRAQKN.AVFFHPRFHVKAEEALKALYAKFCTCGDC..H.E-SPLP.N--------G-S--DATAATA.TESPRPR...LEDAELRLLNYTQLGKFHLPAIRHLTASEQLRVQQSVARDLGF.AD.W.SNTL..VD---DFFLLPVGMSCG..-TPC...QGY....AMYLMSNTVLALRVIRLLYITVRHEQNACVRALCRDVDCLIKMFRYESFSIRK.GLV.............QNAA.............QRMEVSR.F.R--RHVQDLKQ....IKFTVSDLVETFCEFMKIVNRIPDY...QCVSMNIKRELVLLHLLKLRR--------------.....---.......-VYDF..SSPET...RKSERLAWYYLRHGDVPLDAGLLMT-----------------FSSLLADCELSNNANRCRRKVPFEIP----ASAAVTVRYQGHLEKLSRLHVRRFRPHEV.....................................................
G8XSU1_9BETA/263-492                  vepnvp-------------------------------------.----------------------..-.-----.--..---...-..-------------.-------------.-----------------------------..-.------.---------------------.-----CR...LESVPLVLANYRDLGSFRLPALRHLTQSEQRRVRHAVSCDLAF.AL.W.NQTT..SE---PRYLLPSGLSCG..-EVR...RNY....VMYLASNIVFNLKLIRMLHRVIQREFMDGVRFLSSDRDLLVGMLRQRYVMHEK.ALV.............KNPR.............HQKVASEcL.QQIVELRDLDF....SNTGKRSFVESVCDLQDVLKRVPDY...Q-ISLREKQQMFLLHHLRLRRFYTESSSETKLGEN.....LI-.......-----..-----...-----------------------------------------------------------------------------------------------------wyylkrgnevs..........................................
UL27_HCMVA/163-603                    ......VHEAQYLPEISRAAKRIALAVATGQYVVCTLLDYKTF.GTRTHYLRQLCSMTEELYLRLD..G.TLCLF.LE..PEE...R..ELIGRCLPAALCR.-GLPVK-YRTHRA.AVFFHATFMARAEAALKDLYAAFCECGDG..R.D-----.NGGNHDGNHDGNDHSSLSPSA.VASHHSR...LEHAELRLERNRHLGAFHLPAIRHLTAGDVARVQDSVSRDLGF.AD.W.SQTL..ID---DYFLLPAGWACA..-NPR...RGY....AMYLASNAVLALRIIRLLRASIRHEYTACIRMLSGDVQRLIRLFKGEAALLRK.GLA.............QNPV.............QRRELSR.F.R--KHVHDLKR....IRFTEDTFVETFCDFLELVQRIPDY...RSVSLRIKRELLCLHVFKLRR--------------.....---.......GCRAP..PTPET...ARVQRLLWHSLRHGDAPQDRTRLPQ-----------------FSSALSDAELSNHANRCRRKAPLELGPAVVAAPGPSVRYRAHIQKFERLHVRRFRPHEV.....................................................
UL27_HCMVM/163-603                    ......VHEAQYLPEISRAAKRIALAVATGQYVVCTLLDYKTF.GTRTHYLRQLCSMTEELYLRLD..G.TLCLF.LE..PEE...R..ELIGRCLPAALCR.-GLPVK-YRTHRA.AVFFHATFMARAEAALKDLYAAFCECGDG..R.D-----.DGGNHNGNYGGGDHSSLSPSA.VASHHSR...LEHAELRLERNRHLGAFHLPAIRHLTAGDVARVQDSVSRDLGF.AD.W.SQTL..VD---DYFLLPAGWACA..-NPR...RGY....AMYLASNAVLALRIIRLLRASIRHEYTACIRMLSGDVQRLIRLFKGEAALLRK.GLA.............QNPV.............QRRELSR.F.R--KHVHDLKR....IRFTEDTFVETFCDFLELVQRIPDY...RSVSLRIKRELLCLHVFKLRR--------------.....---.......GCRAP..PTPEA...VRVQRLLWHSLRHGDAPQDRTRLPQ-----------------FSSALSDAELSNHANRCRRKAPLELGPAVVAAPGPSVRYRAHIQKFERLHVRRFRPHEV.....................................................
H2A336_MUHV1/156-448                  ...lfd---LEWRPEASDSCKALGRATVAIQYAISLLYGYDRS.ASMSRYLRRLVNELIDLHDRMR..NmSLMSS.LR..IPG...RdlEIVQRLLPERICQqLGIPFS----F--.ESCLLDSYYECVEMTMEVIYDQLCYCREC..R.MRRGER.LERLRAQKIG-TKYRRRNPDG.IRL----...FEENYVRVAAYPNIGVLRLPKIRHLSDEHQTLVCGHLARDLMY.DVhFgSSSP..L-ARVNGIPLPFTAVDC..MDID...LGY....ALYMANNVYFMLFLIRCVRDVVRSEQREYVDLVTGLVREASVMLRRDVD----.---.............----.............-------.-.-----------....-------------------------...-----------------------------------.....---.......-----..-----...-----------------------------------------------------------------------------------------------------ariragadrpvfvas......................................
U6H6M3_9BETA/151-528                  ...ldr---VEFRPEATDVVKVMCKALATAAFCMEHHFKYRNP.GSLSGYVRFLNYVACLTYREVE..D.AWSSL.SN..GDAyacR..SLMN-CLNS----.--RKKKGRSGPLQ.KAVMDKEYVSRVNVMFERAQIALCGCDEC..T.S-----.-GSRHMTTRAVG-----RQNV.VEPHLFV...LNYPEM--------GPVNVPTIKHMSVDEQIAYCEGVRGDCLC.-S.Y.AKKIkvWKDVLDPDTLPVKPDYS.hLLSE...RAR....FLTMVANFIVLCQMTQLAAAVLKCEICRCVVAVKELTQEVSEIVTRQSDLFAGgGLV.............ESKAa..........rsQHKALRR.L.S--ARLRGLNF....GGGSGLIFLPAMGELLKLSTMVSEY...SEINEIQTREELLLHVMFLRRMYDDTSEDMYRAER.....LVQ.......-----..-----...-----------------------------------------------------------------------------------------------------falrhgcgspytpqdvsrtv.................................
Q9DWG2_RCMVM/88-381                   ....ia--AMQFRPEANEVVRALCRACVAAQYGVSILFSYDHC.AAVPRYLRSLVQELVELNDRIRhlS.IVSNLrVE..AED...L..GVIQGVLPERVAA.-LLGVP----AAH.ELFLSDEYYDCVEAAVDAMFDRFCECAECgmR.RSERIV.AVRAR--ALG--DARGLTARRgMLRKKRRnrfFEENDVALPFCPELGRLRLPRIRHLDLVQQELLCRHIGRDLMF.-D.S.MFGV..CRGMSRMRGVPIPFCSAekLNLD...LAY....VLYLASNSYFLCFLIRTVRDVMRHEERAYGELCLG------------------.---.............----.............-------.-.-----------....-------------------------...-----------------------------------.....---.......-----..-----...-----------------------------------------------------------------------------------------------------lardaaralredvearvaagavp..............................
A0A1L6Z0S2_9BETA/142-572              ..vaag----PFLPEISKSGKRIALAVATGQYAVSTLLNYKVF.GNKTHYLRQLCVITEELFRRLA..G.TVCLF.LD..ASD...R..DLIQKCLPSHLCK.-KLPVN-YRVQKN.AVFFNSRFGLRAEAALHTLYARFCTCGDC..H.DLFAAS.SDTQATP-------SEDEPS-.--PPQPR...LEDAELTLLHNAHLGKFHLPAIRHLTAAEQLRVQQSVARDLGF.TD.W.SHTL..VD---DYFLLPVGLSCG..-TPC...EGY....AMYLMSNAVLALKVIRLLYITIRHEHSACVRALCKDVAFLIRMFRYEASIIRK.GLA.............QNAA.............QRMELSR.F.R--RHIHDLKH....IHFTVSNFLETFCDFIKIVNKIPDY...QCISLTIKRELVLLHLLRLRR--------------.....---.......-VYEC..PSAET...RKGEKLAWYYFRHGDVTLDPGILMT-----------------FDSLLADCELSNNANRCRRKAPFEIPT----SATVTVRYQGHIEKLHRLYVRRFRPHEV.....................................................
A0A1P8VIS1_9BETA/50-410               .....l-NNAEFVPDFKPELQAISKLAVIILYSSMSLYNLKDK.ISLCYWCRYCAECLNVMFGKFH..D.TLKDL.ES..EDY...D..AASP---LLSLIK.-DNTFQYDPAERS.SLFFRYDFYQTMQDIYIECMMMMCGCDEC..R.RIFF--.NYKNKKNDEI-----------.--FMSVY...CDVFPE-------LGILELPILPHFGVYNMKHLKDQFKKDLCL.--.-.--SL..IYGQVKKRRFPLKFDFD..--PD...KINvyvdLLTMLGNIVFMLYVVNKIHAAVKKENSMYKEFVDTQVKVLVEWLQNCKTIGTI.GCF.............SDPF.............RSRLGKV.Y.STVKNTHIF--....-----DHIMDFLIPIVRNGMQLPDY...FNFKYRDMHIKFLKHVFDIERDFVLNCSDLIAADN.....LTH.......GYMLI..SS---...-----------------------------------------------------------------------------------------------------dvndvmtsvfngs........................................
I3VPZ5_9BETA/167-558                  .vcgas-----FRPDTCPIVQRLAVAVASGQYAVNTLLNYRNK.SSVAYYIKYLSKKIMFCYRELK..E.RSAGL.TD..KLS...R..LAAGGMMPLPVCR.-KSGLG--QNYRSkAYLLDPEFVAESFRSLQFVYRYLCGCGGC..C.Y-----.-TNSLAWMYP-------NVPL.EANHVLF...NRCAEM--------GPIWLPPIRHLTAEQRIEMCRMFSEDLCL.SV.W.RSGE..VE---DTDVFPCTAPES..LDPV...KWS....VIHLSESICSILSVLKALSSVLSTELNAYATYLQEDVNVIGDMLWDKGYGLSQ.AVA.............RDPS.............QAGRFNR.Y.DGLPDMFRGLR....FGSDAVSFFDAVCCLLECANVVPEY...DALPEYSAREELLLHNFFIRRIYT-----------.....---.......-----..EM---...-----------------------------------------------------------------------------------------------------pdetrlaepylvhclrhgdflpqdavslrslrlelsnaelcnsrmhkgfwepl
K7Y9Z1_RCMVE/155-551                  ....ln--RLEYRPEATDACRTLCRATVAVQYAISILYGYDRS.ASVPRYLRRLIDEYIDLQDRIR..RlGIVPV.LKisGKD...M..NIVQNVLPERVCAqIGIPFT----YEA.--CLLDEYYDCIESNIEQMYDLLCMCKEC..G.MRRMER.FERVRYNTIG-----ERYPKK.KRDRERF...FEENYVIIHSHPDLGVLKLPKIRHLNPLQQLMMCRYLSKDLLYdTQ.F.GPSN..AFSRAQGVPLPFSAVQE..TDMN...IAY....ALYLASNSYFMCFLLRCVRDVLRHEEEAFRKLILRLVNEAVEIIRDDVNSRVW.AGA.............DSPVfvcvdpresgisaEERDLAI.A.RSLEELTFS-N....ELVEGSHFGGFCRDAARFLDLIDAFhfpKALREHRAREDLLLHTFKIEKMYDNRPLSAYYGDR.....LVP.......-----..-----...-----------------------------------------------------------------------------------------------------yhvlmgghrrr..........................................
E9RH41_9BETA/151-529                  ...ldr---VEFRPEATDVVKVMCKALATAAFCMEHHFKYRNP.GSLSGYVRFLNYVACLTYREVE..D.AWSSL.SN..GDAyacR..SLMN-CLNS----.--RKKKGRSGPLQ.KAVMDKEYVSRVNVMFERAQIALCGCDEC..T.S-----.-GSRHMTTRAVG-----RQNV.VEPHLFV...LNYPEM--------GPVNVPTIKHMSVDEQIAYCEGVRGDCLC.-S.Y.AKKIkvWKDVLDPDTLPVKPDYS.hLLSE...RAR....FLTMVANFIVLCQMTQLAAAVLKCEICRCVVAVKELTQEVSEIVTRQSDLFAGgGLV.............ESKAa..........rsQHKALRR.L.S--SRLRGLNF....GGGSGLIFLPAMGELLKLSTMVSEY...SEINEIQTREELLLHVMFLRRMYDDTSEDMYRAER.....LVQ.......-----..-----...-----------------------------------------------------------------------------------------------------falrhgcgspytpqdvsrtvt................................
VU7_HHV6Z/462-885                     ......VKNLKFMDNFDEKWQCITKLAFIGLYAGASLFNFASK.PTLGYWCRYLCEYASMLLFQFE..S.KLKEL.TK..EST...R..QLGG----YNLCH.WGQELKDCLENKS.DVFFRYDFFERIESCLIEHFMLLCGCVEC..R.RMFIMY.NKRGRKCDFG-----------.---HCVR...IQCFPM-------IGSIRLPAFLHLGEPYSVSLSSLIAKDLGL.--.-.--SM..IEGQIEHSRLPISLQIS..VTPD...KKA....LLTFLTNIVFIVFVVNTLYRVINAELDIYYDLFTEEVGKLCVTMEEEMKLGRN.GCL.............----.............--GDLCY.F.SSMKQMKEIVR....CPGEKSQFILKCWEALRIGFSVPAY...KDYDETRFMEMFFLHHLHIKRFHEHNDRDLVSSDN.....LIP.......GFFIV..NTHEE...NFLQRL------------QRVVLPVAEDYLTNTRCINGTMAFFFSGLKYFGSGNHR-------------GVQISPEKDVRAIGY--KLGSLDVLR-DDYKY.....................................................
A0A192XNI0_9BETA/787-1209             .....i-QDLKFMDDFDPKWACITKLAAIGFYSGASLFNLGAK.PGIGHWCRYLCEYLSMLFFKLD..N.RLREL.TK..ESK...E..KLGG----FSCAF.WSESFKIEMQNKT.ESFFRRDFLDRFQLYLLEHFLLFCGCEEC..RfNLFRFK.NLGTMKKNLG-----------.----CVK...LHFFQA-------LGKIDLPIFPHLAEQYSRNLVTFLARDLCL.--.-.--SF..IEGQIERCKLPISINLN..VTQD...KKN....LLNILSNIVFLLYVIQTLYSVLLTELKMYYDVYIDELKNLATSMEFEIKLGSK.GCL.............----.............--NNVRY.I.SMLNQVLDMIG....NPGTSTNFIFNCLEAIKIGFEIPYY...QNYDESKFLDSFYLHHLYIKR-HGEKSVDLIAADN.....LAP.......GFFIV..NAKER...RFIDVL------------EKSILNIEAEYLSNTKNINGAMAIFFSGLKYFGNTGYG-------------EIQVSPEKDVRAIGY--KLGSLGK--------iqndiyy..............................................
VU5_HHV7J/425-846                     .....l-RDLKFMEDFDPKWQCITKLAAVGFYSGASLFNLGAK.PGIGYWCRYLCEYLSMLFFKLD..G.KLKEL.SK..ESK...Q..KLGG----FSCAF.WSESFKTEMQNKT.ESFFRRDFFDRFQLYLLEHFLLFCGCEEC..R.YNFFRFkNVGTMKKNPG-----------.----SVK...LHFFPA-------LGKIDLPIFPHLSEKYS-NLSMFVAKDLCL.--.-.--SF..IEGQIEHSRFPISVTVD..MGQD...KRN....LLNILSNIVFLLFIIQTLNSVLFTELKMYYDVYLDELKNLESSMECEMKLGSK.GCM.............----.............--NNIVY.F.NMLKQVKDIVR....NPGTSSNFIFNCLEVIKMSFEIPYY...KNYDETNFMESFYLHHLYIQR-QPAKHTDLVAANN.....LAP.......GFFIV..NAKEK...SFIDVL------------ERSIVNIEAEYLSNTKNINGAMALFFSGLKYFGNFGNG-------------NFQTSPEKDVRAVGY--KLGGLDKI-------qndlcy...............................................
#=GC seq_cons                         .........hpFhPEhocss+plshAsAsGQYulsoLhsY+sh.uoho+YlRpLCphsppLapRLp..s.sls.h.hc..sss...R..pLltphhs.plCc..thslp.hpsp+s.slFFcscFht+sEtsLpphYtthCsCs-C..+.c..h...ttttth.ths................ps+...LEpsplhl.t..pLGth+LPsIRHLosspphplpptlu+DLsa....a.spoh..l-...-hhhLPluhssu...sss...cuY....shaLhSNhVhhLhlIphLhtsl+pEhsshhchlsc-VptLhphhct-sshhpp.Ghs.............ps.s.............pphplsc.h.p..ccl+-l.t....hthshssFltshs-hlclspplP-Y...psls.p.t+E.hhLHhhcl+R....................................st................................................................................................................................................................
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