#=GF ID   Herpes_UL46
#=GF AC   PF03387.18
#=GF DE   Herpesvirus UL46 protein
#=GF AU   Mifsud W;0000-0002-9805-6461
#=GF SE   Pfam-B_2545 (release 6.6)
#=GF GA   25.00 25.00;
#=GF TC   61.40 60.10;
#=GF NC   23.20 21.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF DR   INTERPRO; IPR005051;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF SQ   35
#=GS TEG1_GAHVM/9-448         AC Q77MR6.1
#=GS J9QWM4_9ALPH/23-450      AC J9QWM4.1
#=GS A0A109Z776_9ALPH/26-440  AC A0A109Z776.1
#=GS A0A1V0M8I9_9ALPH/17-446  AC A0A1V0M8I9.1
#=GS Q2QBD0_CHV16/26-441      AC Q2QBD0.1
#=GS Q9DH38_MEHV1/2-393       AC Q9DH38.1
#=GS D1FXT6_FHV1/30-460       AC D1FXT6.2
#=GS A0A060Q4Z8_9ALPH/24-439  AC A0A060Q4Z8.1
#=GS A1YZN5_9ALPH/22-443      AC A1YZN5.1
#=GS ATI2_PSHV1/45-452        AC Q6UDL7.1
#=GS O89244_9ALPH/29-444      AC O89244.1
#=GS Q7T5D2_CHV1/25-434       AC Q7T5D2.1
#=GS G9CUF8_9ALPH/9-448       AC G9CUF8.1
#=GS Q77Q59_9ALPH/9-448       AC Q77Q59.1
#=GS O56870_ILTV/57-424       AC O56870.1
#=GS A0A0U2URJ6_9ALPH/5-428   AC A0A0U2URJ6.1
#=GS Q9E203_CHV9D/37-451      AC Q9E203.1
#=GS TEG1_VZVD/41-474         AC P09264.1
#=GS A0A1R3T8L4_9ALPH/2-438   AC A0A1R3T8L4.1
#=GS Q9YQ38_9ALPH/14-418      AC Q9YQ38.1
#=GS A0A0K1R1Z9_9ALPH/9-333   AC A0A0K1R1Z9.1
#=GS TEG1_HHV2H/24-456        AC P89466.1
#=GS A0A077B9N6_9ALPH/9-432   AC A0A077B9N6.1
#=GS A0A068ER45_9ALPH/17-446  AC A0A068ER45.1
#=GS TEG1_HHV11/24-471        AC P10230.2
#=GS A0A089N3X5_9ALPH/5-428   AC A0A089N3X5.1
#=GS K9MHV4_9ALPH/24-456      AC K9MHV4.1
#=GS L0N6A1_HHV1/24-471       AC L0N6A1.1
#=GS A0A172DSH0_9ALPH/27-461  AC A0A172DSH0.1
#=GS A0A286RUG3_9ALPH/5-422   AC A0A286RUG3.1
#=GS A0A1S6JLM5_HSVA1/25-452  AC A0A1S6JLM5.1
#=GS E2IUC4_SHV1/24-449       AC E2IUC4.1
#=GS A0A1P7TZM5_9ALPH/29-444  AC A0A1P7TZM5.1
#=GS TEG1_EHV1B/10-428        AC P28937.1
#=GS A0A1L5JKE8_9ALPH/4-424   AC A0A1L5JKE8.1
TEG1_GAHVM/9-448                    ......................................QSLELFDRDSPQEYSCILPNE---LTVSASALRALEDSLiekLPSGLTLGIRESVLCE.T.LSNKVPESVIVHLALGDVRGEYISLYSANVKRRLKRAALTPAVVKDYYTDSYQRYVckrRRIPCVDL..PGTRE.....P....A-....--....RSTV..A.LLFYPAIQRNPLTQKPFRLQKDNKMFVKCWAEIWDALNFIQKYVYYMRPDEITTPSLDTSARLELLFGYVKTLYMWAMWLMDLLDT-----------RIVSNKF...GTRVPi....siDNIFSNLTEvMGSLSSDKWMSTA.....L.LCRSIEHLLSSLIHISSL...WTCCQW..RETKHGeMLRPIVSIVALVSLLHHHCQYIINITFNGYARWLEGGLGNPMLRSAIRQQKRFEHYLGGLFPSIRPTAWGELEFSIRAWFELALAKSMVIHGSllkksivsnnvlEPlcKPRHTQI--.-GERHDT..............RFTRSTSM..PS.SSGHIHSTLQNNQQAIV........................................................................
J9QWM4_9ALPH/23-450                 ...................................ltv--------SERLARGCLLPTEEGIIRAAICELRNRSDEV...QPQSVGVARASSVSAK.G.QYNSVPERVIADSIASDPTYKYLQHYVTAAERALEDCGLSDREIWQGIIDQYWKHL...RAVVGDAL..MLPTP.....A....AG....GA....DPSL..H.ILLRPTLCAKPLAPAPFKGSSHASLFATTIKGLREALHRVQQYVFFMRPEDPSAPSEDTARRLDELLAYTTTLYRWAEWLLWTTDKHVIHQLCPTRADDICRHQ...HA-PP.......SEMLEQHFK.QFSDTTAADTQYM.....V.LRAAICGSFGNIRRLAGL...WETGKR..RTSACG.TADAIVAAIEVLSLVHHHAQYILNATLVGYVVWADGCLENRRLLAAASAQDRFCRMAAPIFHATTTASWARMEVSMQAWFTAALACRMFTGGW............-P..TPHYERAIA.TV-----..............--------..--.-----------------apanhpgqgggggddeccyasmargranargp........................................
A0A109Z776_9ALPH/26-440             ...............................rnpsflp---------QRIHGSCILPTPDCLIGSAVRALRYHSDEL...QPPFLTDADRAMR-VD.I.TSNSVPEDLILDGISRDAQRTYFKHYLAAAKRSLVDNELTNDELWRGIQMQYWKYF...QRVVEGKI..TIPAP.....Q....AR....DR....DPSV..H.VLLRSSVTPKLLSRSPFKPPEQSAKYTQTICKLYEATHKIQQYLYYMRPDRADAPSEVTALRLSELLAYVSVLYKWADCMMLITDKYICECLDPSHQQLKISSR...NLPQS.......GTLFSQHLT.HGPGAGSKSLECY.....A.LRTLVSDVLGYLTHVAHL...WEFGKR..RRGDGG.TPDTIVATIEILALVHHHAQYIINTVLTGYVVWATDGLENIQLRDAVTHQDRFCRVMAPIFPSLTVSSWAEMELGLKAWFTANLATSFLPELT............-P..SPHYETMLQ.A------..............--------..--.-----------------lvgecgssrcndgsgap.......................................................
A0A1V0M8I9_9ALPH/17-446             ................................iaanal-------VKRRIHEGCLLPSL---QTVSRSALRALEDSVepyLPNGMLAARRDEVLQT.T.PGNGVPETIIIESVLADGNGSYISHYRDAVKKSLKQHGVTSDSAWTSFSSEYWKYL...SNSSGLKL..MVEQKgqaatS....SD....QR....KTSV..A.LLLRSAFNEKPVSKHPFKESSKNSVYFKTLKEMRRSMDTIQRYMYYLRPNDPMNHSPHTAVRLAELMSYVSVLYRWLLWLMDTIDGRVLKEMGYIPSG-DGPRE...-CRTP.......DDLFEKHIR.RGPAAMAEDACAS.....A.LANLTHDVLMALLKLSLL...CSVAHW..KRKTSG.VMSAVVSTIELASLVHHHCQYIINMMFLGNVCWLEKGTNDPALQTALRNQGRYCHFLGRLAPIASSHSFAQMERGTSAWFNLAIARACVRHGG............-P..TPHFLL---.-------..............--------..--.-----------------svtgeksepllkaqcedarrtdreagsrpqs.........................................
Q2QBD0_CHV16/26-441                 ..................................pdag------AAATRIFGGCLLPTPEGLVGAAVGALRQRSDDL...QPAFLIGAARAAQLAA.R.RHNSVPESLVVDGITGDSNCEYFKHYAAAAAESLAEAGASSGGLCRAILAQYWKHL...QAVATGGL..RIPEG.....S....PG....EG....DPSL..Q.VLLRPALVPKLLARTPFKSGAQSARYAAAVAGLRDAIHRLQQYMFFMRPDDPCRPSADTALRLGEILAYSRALYDWADWMVQTADGQVCRRLDPTGRRCAAPAR...TAAAP.......ADAFDRHLD.RGPGGTTGSLQCM.....A.LRAAVCDVFGHLRLVAHL...WERGKR..AAATYG.TVDTIVSTVEVVSIVHHHAQYLLNAALAGYVVWASGSLNNEHLRAAVERQERFCRTTAPLFPTMTASSWARMERSIKAWFEAALATELFRTGV............-P..SAHYEASLR.LL-----..............--------..--.-----------------sappgapaaredadpp........................................................
Q9DH38_MEHV1/2-393                  ............................ekrmesnctp---------------------------------------...-PFGLDSKFRQSVLRD.T.TDNGVPEYVVLRLALGDAVGQYMHRYMYNIKRRLKRAKLSRSEVKRHFLAAYNSYF...CERHSIPY..TETRD.....P....TE....RG....KAAL..A.LLFYPTIYRDPLVENPFKCQNHNLIFRNCWTSLRNLFDMIQRYAYYMRPDKIGEASSDTSARLELLLSYVVMLYKWMLWLVDTLDM-------TTGSKFIACRY...TGDVG.......ESLKEFMEE.ISSLPSDKWSSTS.....L.LCRIIGNVIAPLLQTSVL...WSQTRL..VDFDGDrNSRAILAVVSLVSLLNHHCQYLINLTQRGYVIWLDGNTENTILKEALLQQDQFEHQLGNLFPSMLPVSWGALECSINTWFGRAATDDV-----............--..---------.-------..............--------..--.-----------------klsknalallgikllpkrisdvnarlmksirkqdknsnksgst.............................
D1FXT6_FHV1/30-460                  ..................................vgva----ENLLERRVEKGCMLPTPAEILESAVSALKESAENL...SGPGLFCMERVTALSR.I.RDNTIPETIITTCMGKDNGEEFRRGYIMAARRVIEGLNMTRAGIWQIMIKNYWTYL...KTSSGTDM..TVDSR.....T....P-....--....SSLK..V.MLLWSTFSGKRLSKQPFKHSKQNDNHEALISELKRVMITLEKYAYYMRPDDPMSKSTDTMLRLHEILAYVSVSYRWLLWFMDLLDNRVLCAMDKKPIIRHGPRE...SQ-SP.......RDFIQRHLT.SGPGISSGTGEAL.....L.LSAETANALATLLRISSM...WSYGKW..STHTHG.VTSTIVAALEMVTQIHLHLQYFINLVFGGYMCWAEGGMEDSYIRSALRLQGRFNHYIGAVIPVMSALTWSGMEKSVSCWFKYSLAKSLIGHVT............-P..TQHYLGILG.SIERGRR..............RSTRERAKteRR.CVSQ-------------mmthidrqslpl............................................................
A0A060Q4Z8_9ALPH/24-439             ...............................rgesgsl-------LSQRIFAGCLIPTPENLISAAIGALRQHSDDL...QPAFLISANRSVQLSA.R.RANAVPESLVVDGITGDPQYAYFKHYAAAAMRSLEEAELPSAELCRSILSQYWKYL...QTVVTSGV..EIPDG.....H....AG....DF....DPSL..H.ILLRPTLATKLLARTPFKHSSQASKYATTVATLRDALHRLQQYFFFMRPDNPSAPSADTALRLNELLAYVSVLYGWASWMMWTTDKYVCHRLAPSKRKFVNLSK...TFETP.......MEMFTRHIE.RGPGGTTGSLQCM.....A.LRAAISDVFSNLKRLSHL...WEHGKR..SSGSCG.TTEAVVSTIEVVSLVHHHAQYLIHGVLTGYVIWASGGLENDYLRAAVESQERFCHNTAPLFATMTTPSWARMEMSMKAWFGASLAADLFQTGT............-P..SPHYEAILR.LLATHGP..............T-------..--.-----------------ahpplapa................................................................
A1YZN5_9ALPH/22-443                 ...............................lsgsdli--------ARRLREGCIIHRPQDVSLSALRALEAEAEKI...LPFQLFATQRTEVLLK.T.RCNNVPESIIISNVMSDTNGAYISNYASEAKATIKDTGLNKGASWSVILARYWKYL...RHSSGADI..VVNSS.....T....SS....TRallgNVTP..I.LILRSTFEPKPLSKRPLKGKKVTASYLEQLTELKSNFDLVQRYMFYMRPEDPMQASISTDIRLREIMTYNSILYRWILWFMDLFDSNVLRAMGYVTGTNGAREA...--RQP.......EMLFGRHLR.SGPGATDTSGNAV.....A.LTWFTHNVLSSLLKISVL...WSSSKW..HSGTNG.VSSAIVAAVELVTMVHHHCQYLVNMIMAGYICWIKGGAKDTVLQSALRSQGRFCHFIGRLAPTMTVHSWSEMEKGTRAWFKMAHARSIITHGK............-P..TKHYLTT--.-------..............--------..--.-----------------vgsvddpfadtvdnsddddtetl.................................................
ATI2_PSHV1/45-452                   spvwsleqaslnslaataetmlpgpilgpsraehfngp---------------------------------------...----------------.-.-DPTIPDKMVVRMVEGDHKMLFRATLDDTYHILVTRIRVREKFVQRLARAMYTRRA...SMLMDVEL..PFKDK.....M....EG....VYa.aaDLEA..I.CKMHYWVFPHT-VPAPNMKSPDDKAYLTSVAQFARSTKFIESYMYYMRPHDPEVNSTDTGNRVAAMLIYIHGMQCKLASLFDALDAAILRSKFNAGSRGHSLSGiygFTRNG.......KGTMMAAKS.SGNVVEQIRRTCP.....FgSDAMVECLISALDRMTYLvarWELMS-..VDKRDD.AKAAIAAGMGLAWLLNGHLSYLTNMIMTVYVLWLPEHYLNPRLILTISSR-------------------------------------------............--..---------.-------..............--------..--.-----------------vllgqllctshttfrenatcpkmllaqnavewkkqergtaawldyvcarawlrasrenrkpanitamnntle
O89244_9ALPH/29-444                 ................................nsrsrg------SPTRVQEYPCQLSET---TGTSLSGIRAQEDALvevLPSGFLSALRQTLLRD.A.PSNKVPECIVVYLALGDASEEYTRPYRARIARRMKKKKLTRASVKRCYQASYMNYLemrRDGCRAGS..PETCD.....P....T-....--....RREA..A.LLFYPIINRNALVKKPFQLAKDNALYLRCWREIRDGTELIQKYAYYMRPDDVTAPSADTSIRLQLLLSYVRTLYTWAVWLMDVLDLRACP-----------NVF...GPRAPs....dfDTVFLALAEaVSSLPSESWADTT.....M.LCHFIGTVLAPLVHMGAL...WTCCAW..RSSPESeVSRPVVAIVALVGLLNYRCQYILNMVFNGYAVWLQGGMANSTLRRALRQQKRFQCFLGELFPTMNSCTWADTESTVALWFKHARVKSTVTY--............--..---------.-------..............--------..--.-----------------qpaakggdsvvrclqdspqqskrawvedggetse......................................
Q7T5D2_CHV1/25-434                  ...................................rhd----AGAASTRIFGGCLLPTPEGLVGAAVGALRQRSDEL...QPAFLTGAVRAAQLAA.R.RHNSVPESLIVDGITGDPNCEYIKHYAAAATESLAEAGASSGALYRGILSQYWKHL...QAVVSGGL..RIPEA.....P....PT....DC....DPSL..Q.VLLRPALVPKLLARTPFKNGAQSARYAAAVLGLRDAVHRLQQYMFFMRPDDPSRRSADTALRLGEILAYSGALYDWAEWMVQTADAQVCRRLDPTGRRCVPPAR...TAPAP.......ADAFARHLD.RGPGGTTGSMQCM.....A.LRAAVGDVFGHLRVLAGL...WERGKR..GSATCG.TVETIVSTVEAVSLVHHHAQYLLNATLTGYVIWASGSLDNEHLRAAVERQERFCRATAPLFPTMTPSSWARMERSVKAWFEAALATELFRTGV............-P..SPHYEASLR.LL-----..............--------..--.-----------------ssppgalpp...............................................................
G9CUF8_9ALPH/9-448                  ......................................QSLELFDRDSPQEYSCILPNE---STVSASALRALEDSLiekLPSGLTLGIRESVLCE.T.LSNKVPESVIVHLALGDVRGEYISLYSANVKRRLKRAALTPAVVKDYYTDSYQRYVckrRRIPCVDL..PGTRE.....P....A-....--....RSTV..A.LLFYPAIQRNPLTQKPFRLQKDNKMFVKCWAEIWDALNFIQKYVYYMRPDEITTPSLDTSARLELLFGYVKTLYMWAMWLMDLLDT-----------RIVSNKF...GTRVPi....siDNIFSNLTEvMGSLSSDKWMSTA.....L.LCRSIEHLLSSLIHISSL...WTCCQW..RETKHGeMLRPIVSIVALVSLLHHHCQYIINITFNGYARWLEGGLGNPMLRSAIRQQKRFEHYLGGLFPSIRPTAWGELEFSIRAWFELALAKSMVIHGSllkksivsnnvlEPlcKPRHTQI--.-GERHDT..............RFTRSTSM..PS.SSGHIHSTLQNNQQAIV........................................................................
Q77Q59_9ALPH/9-448                  ......................................QSLELFDRDSPQEYSCILPNE---LTVSASALRALEDSLiekLPSGLTLGIRESVLCE.T.LSNKVPESVIVHLALGDVRGEYISLYSANVKRRLKRAALTPAVVKDYYTDSYQRYVckrRRIPCVDL..PGTRE.....P....A-....--....RSTV..A.LLFYPAIQRNPLTQKPFRLQKDNKMFVKCWAEIWDALNFIQKYVYYMRPDEITTPSLDTSARLELLFGYVKTLYMWAMWLMDLLDT-----------RIVSNKF...GTRVPi....siDNIFSNLTEvMGSLSSDKWMSTA.....L.LCRSIEHLLSSLIHISSL...WTCCQW..RETKHGeMLRPIVSIVALVSLLHHHCQYIINITFNGYARWLEGGLGNPMLRSAIRQQKRFEHYLGGLFPSIRPTAWGELEFSIRAWFELALAKSMVIHGSllkksivsnnvlEPlcKPRHTQI--.-GERHDT..............RFTRSTSM..PS.SSGHIHSTLQNNQQAIV........................................................................
O56870_ILTV/57-424                  ....................dpkrildnsspsdlavla------------------------------------ERE...LPSSLLGPAREEYL-K.F.GDKKLPDNFISRTVSNDTTDEYRRNLDEAFKLFIARRGVTEKCVARMLRHLYAKRL...SVVLDLDV..PFGE-.....K....IN....KAlsadDQDF..V.LKLYYWVFPDKVSA-PRLKEPEMQAYLASVTYLSCTFKFIEGYAYYMRPPGPELHSTETTARLAALLVYVRSMYCKLASLFDAIDAAVLRS---KFNRGASAQA...LTGIYgytrngkGTIMSRYSS.E--AMSDEIMSVCrtgsdT.LIESLRKALGRLTYLIAR...WELISV..-EKKRD.AKEAVTAALALSGLVSGHLGYLLNLISMAYVFWLPGHYLNMRLILALSSRELLSHLLAT----------------------------------............--..---------.-------..............--------..--.-----------------npsslrevascpkilfyqsveew.................................................
A0A0U2URJ6_9ALPH/5-428              ....................................aa---SRGLIERRAEKGCLLPTLADATAAAVVALQEATEPL...CGAPLFGAERAAALLG.V.RSNAVPEALVLSDSAKDADDEYRLEYDRAAARVLAGARLSKDAVWRAVIGSYWKYL...KASSGADV..NIDGA.....AggaaME....QA....QLTN..V.MLFAPTYARR-ASRSPFKHKQDNAAYKTAAAELRGALRAVEKYMYYMRPGDPMVESPDTEARLQEILAYAATAYRWLLWFMDALDGTVLRKLGKRPSAAVGPRE...PR-PP.......GELCERHLT.GGPGIACGSGAAL.....M.LTALTAAVLALLLRVGAA...WTESSW..KSNTQG.VTGAIVAAVELASAVHHHLQYLLNMAFVGYACWLRAGVRDPYMIAAIRAQCRFAHFTGQLMPTMTSASWAALERGTASWFKLALLKSVAAHGA............-Q..TRYYSNIVE.S------..............--------..--.-----------------mrlggsrgllapvrarpsgrgr..................................................
Q9E203_CHV9D/37-451                 .....................................r-TLSQRIIQERIRDGCLLPTPNDALEAAVKALYEKTNAV...TPEALHSTERFNALLG.V.HHNNVPESLIVSCMSTDNMGEYLHIYLDNIQKCLDEIKISVEAASRIYENTYWHYL...QRTTGVSI..PISTE.....N....FN....KK....TKST..V.LLFFSTISQKSIAKNPFKCKTVNSNYREAFQLLKEEMGAVQKYMYFMRPDDPMTHSSDTRVRLQEIAAYISTGYGWMLWFLDMLDLRVLKQTKLLFQKTQGPRS...SV-AP.......EDLFKRHLK.KGPAVATGTGTAL.....I.LAATTASSLTSLLKISSI...WQ-NEW..REGLSG.TASAIVAAVELITCLHHHFQYLLNMMLVGYACWGDGGVYDSYILNALRTQGRFLYCAGDLVQTMSIHSWVTLESSIHVWFLWAVARSLLLYKG............TP..TAYYTEILN.RT-----..............--------..--.-----------------ypqntcfllpspqc..........................................................
TEG1_VZVD/41-474                    ......................................CSISQRITSERVRDGCLIPTPGEALETAVKALSEKTDSL...TSPVLQSTERHSVLLG.L.HHNNVPESLVVSCMSNDVHDGFMQRYMETIQRCLDDLKLSGDGLWWVYENTYWQYL...KYTTGAEV..PVTSE.....K....VN....KK....SKST..V.LLFSSVVANKPISRHPFKSKVINSDYRGICQELREALGAVQKYMYFMRPDDPTNPSPDTRIRVQEIAAYTATGYGWMLWFLDVVDARVCRHLKLQFRRIRGPRA...SV-IP.......DDLLRRHLK.TGPAVSAGTGVAF.....I.LAATTASALTALLRISVL...WRKEEW..RDGLNG.TAAAIVAAVELITLLHHHFQYLINMMLIGYACWGDGGLNDPYILKALRAQGRFLYFAGQLVRTMSTHSWVVLETSTHMWFSRAVAQSILAHGG............KP..TKYYAQVLA.ASKRYTP..............LHLRRISE..PS.SVSDQPYIRFNRLGSPI........................................................................
A0A1R3T8L4_9ALPH/2-438              ..................................dlir---------RRIKNGCLVPGPSEVSASAVLALGEQAEVS...APNSLFSAERSVFLSG.Y.PNNTVPETMIVSHVLKDSTGSYLQCYRDSAKRSLKEMSLTKSKAWGSIVARYWKYL...RLTNRIEL..NIEEQ.....P....SAl..pKG....NDLA..H.LILRSTFAASLLSEAPFKDKSTNAAYAANFKDMRATMDTVQRYMYFMRPEDPMVPSEDTALRLKELMAYAAVSYRWLLWFLDLFDSKILSYIGVSTNKLGPRET...--KHP.......EQFFSKHIR.SAACSTGESDCAM.....A.LSTSTSGALTALIKMSAT...WTECRW..KSNTQS.MSAAIVAAVEVVTFVHHHIQYILNMLFSGYICWSAKGAEDQFIISALRAQGRFCHFAGTLAPTMTVHSWAAMESGTAAWFKYSLARSILLHGG............-I..TDYYSRVLK.TI-----..............--------..--.-----------------npddggnatsglistagntfsrcgscrnserstrstrant................................
Q9YQ38_9ALPH/14-418                 ....................................kd--ASRRVTEGRTRASCLLAAPGEVLTAAVAALRDVAESQ...CAPALFGAQRASALAL.V.RSNYAPESVITACSA-EPHRE---VYARAADAALKG--ITADVAWRAVLATYWRYL...KASSGVEV..RSDDE.....R....D-....--....APTV..M.LLW-ST-FGKPLSKHPFKHKAQSAAYGATRAALAEATEAVERYAYYMRPLDPMVSSPQTSVRLHEMLAYAATLYRWLLWMMDTVDARVVRHLGRTPRVARGPRE...TM-SP.......EALFGRHRA.GGPAVASGSGEVL.....V.LTSHTATVFDALEILGAT...WAETPW..KSGVCG.LTAAVVAAVDLVTFVHHHAQTLINLTLAGYVCWLDDGMEDPYLRAALRAQCRFHHLIGDLAPTSSSHAWGAMERGTLAWFNYAIARSLASYGG............-P..TERFARVLA.TTGQRDM..............RFL-----..--.-----------------svapaqp.................................................................
A0A0K1R1Z9_9ALPH/9-333              .........................rgnfgerlckrip---------------------------------------...----------------.-.QPNDVMEQEILDLVHSDRENNYRQHL-TRLETSLQRTTPTPKQLYIVACSAYNEYA...HSVRRIPV..NWHRP.....L....IP....LA....MLTI..I.KRF-SYCFGDSIAFYPSG-IVDDVRFQNQWWTLKTRMEDVEKYLYYCSPNLLDHPSPSTSVRIETLVIYAASLVRFCALLADVLDENMAKQYGHVDHRTRETSG...-----.......EEILDNHTTiTEDNCIPTEYGTE.....W.LRYQTLSILQMVFRMIDE...FKEHQFplKSGKME.MC-AKVLFFFLYSLFFHHATYIFNSIRTLYYWWLPERSHNLMLQSAL----------------------------------------------............--..---------.-------..............--------..--.-----------------glycfvsesissiiidcptlnqwqdeekst..........................................
TEG1_HHV2H/24-456                   ......................................RGANAGVPERRIFAGCLLPTPEGLLSAAVGVLRQRADDL...QPAFLTGADRSVRLAA.R.HHNTVPESLIVDGLASDPHYDYIRHYASAAKQALGEVELSGGQLSRAILAQYWKYL...QTVVPSGL..DIPDD.....P....AG....DC....DPSL..H.VLLRPTLLPKLLVRAPFKSGAAAAKYAAAVAGLRDAAHRLQQYMFFMRPADPSRPSTDTALRLSELLAYVSVLYHWASWMLWTADKYVCRRLGPADRRFVALSG...SLEAP.......AETFARHLD.RGPSGTTGSMQCM.....A.LRAAVSDVLGHLTRLAHL...WETGKR..SGGTYG.IVDAIVSTVEVLSIVHHHAQYIINATLTGYVVWASDSLNNEYLTAAVDSQERFCRTAAPLFPTMTAPSWARMELSIKSWFGAALAPDLLRSGT............-P..SPHYESILR.LAAS-GP..............PGGRGAVG..GS.CRDKIQRTRRDNAPPPL........................................................................
A0A077B9N6_9ALPH/9-432              ...................................hvs----RTLIERRAAKGCMLPTPGDVMEAAVMALKEAAEGL...APARLFSAERTAALSG.I.HNNDVPEPLVTSAVAGDVSGEYRREYEAAARCNLDSTELSQDGIWQVVIRSYWRYL...RESSGADV..VDCGA.....A....GG....KT....QSTL..SiMLLWSTFGKKRLSKHPFKHKSANSNYKEDLEGLRGALSKIERYAYYMRPNDPMTRSENTALRLHEILAYVATCYRWLLWFMDLTDARVLKKMDKGPVITHGPRE...-TRPP.......DELVRRHIK.SGPGVSAGTGAAL.....M.LTTGTADALVILLRMSVG...WTAHSW..KSNTHG.VTGAIVAAVELVTLLHHHLQYLINLVFAGYACWLDGGIDDSYLNSALRAQGRFDHFVGKLVPVMSAASWANMERGVPAWFRYALAKSLVTHGS............-P..TQYYLGVLD.SI-----..............--------..--.-----------------agqraeagergedglsrrtasfs.................................................
A0A068ER45_9ALPH/17-446             ................................iaanal-------VKRRIHEGCLLPSL---QTVSRSALRALEDSVepyLPNGMLAARRDEVLQT.T.PGNGVPETIIIESVLADGNGSYISHYRDAVKKSLKQHGVTSDSAWTSFSSEYWKYL...SNSSGLKL..MVEQKgqattS....SD....QR....KTSV..A.LLLRSAFNEKPVSKHPFKESSKNSVYFKTLKEMRRSMDTIQRYMYYLRPNDPMNHSPHTAVRLAELMSYVSVLYRWLLWLMDTIDGRVLKEMGYIPSG-DGLRE...-CRTP.......DDLFEKHIR.RGPAAMAEDACAS.....A.LANLTHDVLMALLKLSLL...CSVAHW..KRKTSG.VMSAVVSTIELASLVHHHCQYIINMMFLGNVCWLEKGTNDPALQTALRNQGRYCHFLGRLAPIASSHSFAQMERGTSAWFNLAIARACVRHGG............-P..TPHFLLS--.-------..............--------..--.-----------------mtgeksepllkaqcedarrtdretgsrpqs..........................................
TEG1_HHV11/24-471                   ....................................rg--DNAGVPERRIFGGCLLPTPEGLLSAAVGALRQRSDDA...QPAFLTCTDRSVRLAA.R.QHNTVPESLIVDGLASDPHYEYIRHYASAATQALGEVELPGGQLSRAILTQYWKYL...QTVVPSGL..DVPED.....P....VG....DC....DPSL..H.VLLRPTLAPKLLARTPFKSGAVAAKYAATVAGLRDALHRIQQYMFFMRPADPSRPSTDTALRLNELLAYVSVLYRWASWMLWTTDKHVCHRLSPSNRRFLPLGG...SPEAP.......AETFARHLD.RGPSGTTGSMQCM.....A.LRAAVSDVLGHLTRLANL...WQTGKR..SGGTYG.TVDTVVSTVEVLSIVHHHAQYIINATLTGYGVWATDSLNNEYLRAAVDSQERFCRTTAPLFPTMTAPSWARMELSIKAWFGAALAADLLRNGA............-P..SLHYESILR.LVASRRTtwsagpppddmasgPGGHRAGG..GT.CREKIQRARRDNEPPPL........................................................................
A0A089N3X5_9ALPH/5-428              ....................................aa---SRGLIERRAEKGCLLPTLADATAAAVVALQEATEPL...CGAPLFGAERAAALLG.V.RSNAVPEALVLSDSAKDADDEYRLEYDRAAARVLAGARLSKDAVWRAVIGSYWKYL...KASSGADV..NIDGA.....AggaaME....QA....QLTN..V.MLFAPTYARR-ASRSPFKHKQDNAAYKTAAAELRGALRAVEKYMYYMRPGDPMVESPDTEARLQEILAYAATAYRWLLWFMDALDGTVLRKLGKRPSAAVGPRE...PR-PP.......GELCERHLT.GGPGIACGSGAAL.....M.LTALTAAVLALLLRVGAA...WTESSW..KSNTQG.VTGAIVAAVELASAVHHHLQYLLNMAFVGYACWLRAGVRDPYMIAAIRAQCRFAHFTGQLMPTMTSASWAALERGTASWFKLALLKSVAAHGA............-Q..TRYYSNIVE.S------..............--------..--.-----------------mrlggsrgllapvrarpsgrgr..................................................
K9MHV4_9ALPH/24-456                 ......................................RGANAGVPERRIFAGCLLPTPEGLLSAAVGVLRQRSDDL...QPEFLTGADRSVRLAA.R.HHNTVPESLIVDGLASDPHYNYIRHYASAATQALGEVELSGGQLSRAILSQYWKYL...QTVVPSGL..DVPDD.....P....AG....DC....DPSL..H.VLLRATLLPKLLVRAPFKSGAAAAKYAAAVAGLRDAVHRLQQYMFFMRPADPSRPSTDTALRLSELLAYVSVLYHWASWMLWTTDKYVCHRLGPADRRFVALSG...SMEAP.......AETFARHLD.RGPSGTTGSMQCM.....A.LRAAVSDVLGHLTRLAHL...WETGKR..SGGTYG.IVDTIVSTVEVLSMVHHHAQYIINATLTGYVVWASDSLNNEYLRAAVDSQERFCRTAAPLFPTMTAPSWARMELSIKSWFGAALAPDLLRSGA............-P..SPHYESILR.LAAS-RP..............PGGRGAAG..GS.CRDKIQRARRHNAPPPL........................................................................
L0N6A1_HHV1/24-471                  ....................................rg--DNAGVPERRIFGGCLLPTPEGLLSAAVGALRQRSDDA...QPAFLTCTDRSVRLAA.R.QHNTVPESLIVDGLASDPHYEYIRHYASAATQALGEVELPGGQLSRAILTQYWKYL...QTVVPSGL..DVPED.....P....VG....DC....DPSL..H.VLLRPTLAPKLLARTPFKSGAVAAKYAATVAGLRDALHRIQQYMFFMRPADPSRPSTDTALRLNELLAYVSVLYRWASWMLWTTDKHVCHRLSPSNRRFLPLGG...SPEAP.......AETFARHLD.RGPSGTTGSMQCM.....A.LRAAVSDVLGHLTRLANL...WQTGKR..SGGTYG.TVDTVVSTVEVLSIVHHHAQYIINATLTGYGVWATDSLNNEYLRAAVDSQERFCRTTAPLFPTMTAPSWARMELSIKAWFGAALAADLLRSGA............-P..SLHYESILR.LVASRRTtwsagpppddmasgPGGHRAGG..GT.CREKIQRARRDNEPPPL........................................................................
A0A172DSH0_9ALPH/27-461             ................................esknll--------RKRINKGCMLPTPIDIMEAAVVALKENAEKI...SGPGLFCLERSIALSS.I.RNNSIPETVIINCITEDKEDEYRKMYKKMAKGNIDKLNFSSSAVWQVMIKNYWKYL...KSSSGVDLvvDIVVN.....D....SK....TT....QSLT..T.MLLWSTFSEKRLSKNPFKHKSENSKLKDILSELKCYFLKIEKYAYYMRPEDPMSKSEDTKIRLHELLSYTSMCYRWLLWFMDFIDSKVLQKIKKKSVSKQGPRE...TQ-NP.......RELFKRHLT.NGPGISSGTGVSL.....I.LSEEIYKTLSIILSISDL...WTSSSW..SKNIHG.ITKAIISAIEIVSMIHHHNQYLINLVLGGYMCWSEGGMGDPFIIDALRRQGRFNCFVGELIPTIAAKNWFYMEKSVCAWFKFALAKSLVGHDS............-L..TNHYLSVLGsIDNPHAS..............TEERKIVG..KRrASDQVSSIR--------mfnnffnp................................................................
A0A286RUG3_9ALPH/5-422              .................................haaql------LVQQRALRGCLVPTVADATAAAALALRERASEA...CGRRLFSAERDAALSG.V.HGNAVPEALILASVTKDVSAEYRAHYERAVRRILARAKFSGTVAWQIMIAAYWKYL...RLSSGADV..QVDMP.....P....DH....NR....QCHT..N.ILLFASTFEKRQAPTPFRHKPANAGHKALTADLRDATDAIEKYLYYMRPRDPMLASADTETRLRELLAYVATTYRWVLWFMDNLDAKVLQMLDKRPDDARPPRE...-TRTP.......DELCGRYMT.TGPGVRCGEGSAL.....V.LTALTANAMDALVKLGAM...WVTAAW..KSSSHG.VAAAIVAAVELVTGVHHHLQYVVNMVLVGYVAWLREGLDDPYLRSALRAQRRCAHFIGKLIPTMSSHGWCVLDPGTRAWFRYAVFRSVSEHGG............-I..TPHYAHVLR.TATA-DP..............--------..--.-----------------spsvsshapratld..........................................................
A0A1S6JLM5_HSVA1/25-452             ................................genpnl-------ARQRVATGCLLPRPGDVVEAAVRALQQQSDDV...QPPPLLTADRSDRLAQhR.ARNAVPEALIVDAIIADAQHEYLSRYAASAQRALSEATASSGAVWRAILSQYWEHL...QTVTSGNL..QAPET.....S....PG....NC....DPTV..F.VLLRPTFHDKLLAREPFKHRAQNAQYVAATGELREALHRLQQYLYYMRPEFPDAPSADTALRIEELLAYVVALYGWAQWMMWTTDARVCKRLDPGGLRARRRGA...APQIP.......ALAFARHFQ.ESPASRNGSMQCL.....A.LSAAVANVLGCLRRMSQA...WDANKW..ASGAGG.TGEAVVAAVESVSLVHHHGQYILNAMLAGYVAWARDGPRNRALARALRRQETFCRETAPLFPTMTSFSWSGMEQTMEPWFRASVARSLLAFGP............-P..TVHYRAILD.GIPR-VT..............EEGPGAPG..PS.S----------------pvdseaetlsp.............................................................
E2IUC4_SHV1/24-449                  .................................rsyga-----GSVARRLAGGCLIPRPDDIVHSAVRALQQQADAV...QPAILLSVDRSSKLAV.RrDRNAVPEGAIVDAIIADKQRDYFRLYATAARRSLLDSGASSAAVWRGVLARYWKHL...QAVVPGGL..EVPES.....N....PG....DY....DPSL..A.ILLRPTIQAKLLAREPFKHRTQNNQYNATTTELREALHRLQQYLFFMRPDDPASPSVDTALRIEEILACVCALYQWAQWMMWTTDARVCKRLDPEGLRACRPGR...APAPP.......ILVFTQHLQ.EGPVATNGSTQCM.....A.LTAAVASVLGCLRRISQL...WETSKW..ASGAGG.TGEAVVAAVESVSLVHHSAQYALNAVLAGYVTWATDGLHNRRLAAALRQQELFCRDTSPLFPTMTSFSWAAMEQTMEPWFRAALARSLLGN--............AP.lPRHYRGVL-.-------..............--------..--.-----------------dslppsshtetspadrdapaesrpdr..............................................
A0A1P7TZM5_9ALPH/29-444             ................................nsrsrg------SPTRVQEYPCQLSET---TGTSLSGIRAQEDALvevLPSGFLSALRQTLLRD.A.PSNKVPECIVVYLALGDASEEYTRPYRARIARRMKKKKLTRASVKRCYQASYMNYLemrRDGCRAGS..PETCD.....P....T-....--....RREA..A.LLFYPIINRNALVKKPFQLAKDNALYLRCWREIRDGTELIQKYAYYMRPDDVTAPSADTSIRLQLLLSYVRTLYTWAVWLMDVLDLRACP-----------NVF...GPRAPs....dfDTVFLALAEaVSSLPSESWADTT.....M.LCHFIGTVLAPLVHMGAL...WTCCAW..RSSPESeVSRPVVAIVALVGLLNYRCQYILNMVFNGYAVWLQGGMANSTLRRALRQQKRFQCFLGELFPTMNSCTWADTESTVALWFKHARVKSTVTY--............--..---------.-------..............--------..--.-----------------qpaakggdsvvrclqdspqqskrawvedggetse......................................
TEG1_EHV1B/10-428                   ...................................thv---SKNLIERRAVKGCLLPTPSDVMDAAVMALKDVTENI...VGQQLFSVDRTNALSV.I.HTNEVPESIIATAIARDTSRDYLREYEGAAKCNLAATDLSHDEMWEVVIKRYWRYL...RESSGAEV..-VDRG.....A....VG....QA....TQSVlsV.LLLQSTFGKKRLSKNPFKHKGPNVGYKSNLEDLRSAFTKIEKYMYYMRPNDPMTKSEDTELRLHELLAYVTTCYRWLLWFMDLTDAKVLRNIDKGPVITHGPRE...SR-PP.......DELVRRHLK.SGPAISAGTGVAL.....T.LSTATADALIVLLRMSVS...WTSHSW..KSNTHG.VTGAIVAAVELVTLIHHHLQYIINTVFAGYVCWLDGGVENSYLNSALRSQGRFDHFVGKLVPIMATLSWANMEKGTVMWFKYALAKSIVCHGS............-P..TQHYLTVLE.SIAS---..............--------..--.-----------------krtgacppqgstfgr.........................................................
A0A1L5JKE8_9ALPH/4-424              ...................................aaa---SRGLIERRAEKGCLLPTLADATAAAVVALQEATEPV...CGAPLFGAERAAALLG.V.RSNAVPEALVLSDSAKDADGEYRLEYDRAAARVLAGARLSKDAVWRAVIGSYWKYL...KTSSGADV..NIDSP.....A....GGaameQA....QLTN..V.MLFAPTYARR-ASRSPFKHRHDNAAYKAAAAELRGALRAVEKYMYYMRPGDPMVESPDTETRLQEILAYAATAYRWLLWFMDTLDGTVLRKLGKRPPAAVGPRE...PR-PP.......GELCERHLT.AGPGVACGSGAAL.....M.LTALTAAALALLMRVGAA...WTESSW..KSNTHG.VTGAIVAAVELASAVHHHLQYLLNMAFVGYACWLRAGVRDPYMISAIRAQCRFAHFMGPLMPTMTSASWAALERGTASWFKLALLKSVAAHGA............-Q..TSYYSNIVE.-------..............--------..--.-----------------smrlggsrgllapvrrrgr.....................................................
#=GC seq_cons                       ....................................hh........pcRhttGCLLPostthhsuAlsAL+pts-sl...tPshLhuucRsshLss.h.psNsVPEulIlsslsuDspt-YhpcYtsAAc+sLpcspLossslhcshlupYW+YL...pssssssl..slsps.....s....ss....pt....csol..t.lLLtsohstK.Lu+pPFKppspNutYtsshspLRcAhctlQ+YhYYMRPcDPtssSsDTulRLpELLAYVusLY+WhhWhMDshDspVh+phs.tspchhuspt...sstsP.......s-lFpRHlc.pGPusosuotssh.....h.LsstsuslLusLh+lusL...WppspW..+usspG.sssAIVAsVELlSlVHHHsQYllNhshsGYssWhpuGlpNshLpuAlRsQpRFs+hhGsLhPTMostSWuthEpuhpuWFphALA+SlltaGs.............P..o.+Yttllt.......................................................sts..................................................................
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