#=GF ID   His_binding
#=GF AC   PF02098.20
#=GF DE   Tick histamine binding protein
#=GF AU   Mian N;0000-0003-4284-4749
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   IPR002970
#=GF GA   21.20 21.20;
#=GF TC   21.70 21.70;
#=GF NC   21.10 21.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP   Domain
#=GF CL   CL0116
#=GF DR   INTERPRO; IPR002970;
#=GF DR   PRINTS; PR01220;
#=GF DR   SCOP; 1qfv; fa;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF SQ   40
#=GS B7QFD6_IXOSC/28-161    AC B7QFD6.1
#=GS B7P5L3_IXOSC/47-157    AC B7P5L3.1
#=GS B7Q0D2_IXOSC/2-59      AC B7Q0D2.1
#=GS B7QHG0_IXOSC/30-165    AC B7QHG0.1
#=GS B7QFI0_IXOSC/7-145     AC B7QFI0.1
#=GS B7PTZ2_IXOSC/3-154     AC B7PTZ2.1
#=GS B7Q2K2_IXOSC/44-150    AC B7Q2K2.1
#=GS B7QK12_IXOSC/56-133    AC B7QK12.1
#=GS B7QM93_IXOSC/38-127    AC B7QM93.1
#=GS A0A1S4LUK7_IXOSC/1-58  AC A0A1S4LUK7.1
#=GS B7PKW2_IXOSC/72-313    AC B7PKW2.1
#=GS B7Q125_IXOSC/30-189    AC B7Q125.1
#=GS B7PY25_IXOSC/32-182    AC B7PY25.1
#=GS B7PAK0_IXOSC/31-170    AC B7PAK0.1
#=GS B7PQJ6_IXOSC/11-148    AC B7PQJ6.1
#=GS B7PCP3_IXOSC/2-52      AC B7PCP3.1
#=GS B7PK15_IXOSC/4-130     AC B7PK15.1
#=GS B7QKR4_IXOSC/61-207    AC B7QKR4.1
#=GS B7QJ73_IXOSC/1-206     AC B7QJ73.1
#=GS B7QNW8_IXOSC/114-209   AC B7QNW8.1
#=GS B7PVD1_IXOSC/3-151     AC B7PVD1.1
#=GS B7PEZ4_IXOSC/1-137     AC B7PEZ4.1
#=GS B7PU25_IXOSC/1-86      AC B7PU25.1
#=GS B7PMR4_IXOSC/1-34      AC B7PMR4.1
#=GS B7PLN8_IXOSC/39-193    AC B7PLN8.1
#=GS B7QBN6_IXOSC/2-132     AC B7QBN6.1
#=GS B7QIW6_IXOSC/30-170    AC B7QIW6.1
#=GS B7P4F0_IXOSC/38-190    AC B7P4F0.1
#=GS B7Q7M2_IXOSC/105-158   AC B7Q7M2.1
#=GS B7QAQ5_IXOSC/46-174    AC B7QAQ5.1
#=GS B7PR17_IXOSC/30-163    AC B7PR17.1
#=GS B7QAQ4_IXOSC/27-167    AC B7QAQ4.1
#=GS B7Q5U1_IXOSC/1-128     AC B7Q5U1.1
#=GS B7QIW7_IXOSC/36-174    AC B7QIW7.1
#=GS B7QNW8_IXOSC/1-122     AC B7QNW8.1
#=GS B7QC28_IXOSC/2-76      AC B7QC28.1
#=GS B7PBP1_IXOSC/27-95     AC B7PBP1.1
#=GS B7QBN5_IXOSC/2-137     AC B7QBN5.1
#=GS B7QMG6_IXOSC/2-53      AC B7QMG6.1
#=GS B7PA76_IXOSC/31-169    AC B7PA76.1
B7QFD6_IXOSC/28-161               .................................................................................krp---EYNAWKFL-.KSFKSGYIKYQTYVDS-----.-VGCTEFLRKALNATDKSAL...............YQVSFKV..LADNT--.--.KETITLRFHEQI...TP-....NEYAVYNED......EEELYNSTVAYS...D.YSK.CSI...........................IQDSETPTN---..................................CKMFVNT.GTSNRVI...........................................................-QECFKKFPDTC...............................
B7P5L3_IXOSC/47-157               ..................................................................................as--ESQNMSKVL-.FTGEPTNILYRSYQEDPLFGQ.TGTCPYLMPKSTQVPSSSFI...............LELGY--..KQDGKQV.KV.TKHADLITYEKY...PAP....NILSIKPITp....dSREDRRYTLIFS...D.YSN.CSV...........................------------..................................-------.-------...........................................................------------...............................
B7Q0D2_IXOSC/2-59                 ..................................................................................gp------------.---------------------.--------------------...............-------..-------.--.------------...---....---------......--QPLLYKFLNI...N.SDKtCAV...........................LRATHEEDG-TG..................................CELYSARvGGTPLSV...........................................................PQECMNVYIQNC...............................
B7QHG0_IXOSC/30-165               .......................................................................lqeyqnespcfpl------------.--EETWYVAYRNYETDPYFGG.SAKCVRFSETDPGQNGAY-P...............VILEYDP..S-----F.SA.DLTVTLSSSPGY...TLK....NILNFQPQG......QDVSVPAYSAYK...D.VKN.CDV...........................LRMTYAGE--NA..................................CALLVPK.SKLGHH-...........................................................-EVC--------lkasd..........................
B7QFI0_IXOSC/7-145                ..................................................................................lg--KYQDESECF-.PLAESWYVVYRNYEFDPVLGG.TEKCVSDFETRPEVNGA---...............----FPT..VFKIGNE.TV.KTLVTLDSTEGY...TAK....NVLYIRPVE......GNSSVLLYVAYL...D.CKK.CVL...........................LRNVYVDD--AA..................................CSLLVPK.SELGHQ-...........................................................SVCCDFVFDLLC...............................
B7PTZ2_IXOSC/3-154                ...........................................................................pqrkatstn------------.---------------------.--------------------...............-------..-------.--.------------...---....---------......---GTCYNLNFNflcE.SGG.CRIphqecwrprwtkysekyvlfstplcyiVRSLQDEEDYES..................................CEFWLSE.DWLKENVtipqvvtivkeeeseeneeseeneqrkeseerkesvqceeeprnvnkttylydylfkelPSSCRYAFLLSC...............................
B7Q2K2_IXOSC/44-150               .................................................................................nnn---SAKLW----.LTRRKVYLVYRSEKNEIEFGG.EAQCVQMKASDFELPKKKYQynapv....eklkvwSRLRYRN..NETGHMY.VF.VFLYQVLEQICS...G--....---------......------------...-.---.---...........................------------..................................-------.-------...........................................................------------rnklkrgsafvlwytdft.............
B7QK12_IXOSC/56-133               ...................................................................................l-SKYQDATKCL-.PITEKWYIVYRNYESDPLFGG.KAQCGKFSSLGPEED-----...............-------..-------.--.------------...---....---------......------------...-.---.---...........................------------..................................-------.-------...........................................................------------ggfamklqfkhwsmtrsedcrplrsdttmar
B7QM93_IXOSC/38-127               ...................................................................................n-FEHQHATGLL-.CSSYTYYMWSRTHTSQF----.QSECVSVKVTSGLRNGTY-Q...............VLLRHRF..TGSKQMY.SL.NVTVHPFTSGSH...TED....NALFFT---......------------...-.---.---...........................------------..................................-------.-------...........................................................------------fpssky.........................
A0A1S4LUK7_IXOSC/1-58             ...................................................................................t----------IKfTANKSYYLMYSSGWGTKEHYD.DVRCLQVHSSGFNNTLKSAK...............YTSKWYN..ITSKQM-.--.------------...---....---------......------------...-.---.---...........................------------..................................-------.-------...........................................................------------...............................
B7PKW2_IXOSC/72-313               ...................................................................................l-GPLQSAWKAINkSKDDPFVLMFRSRNHEP----.NITCVVVTASLHNETLKIVN...............FTRTYYN..KTEGKND.TL.EYQVRALNQTDY...KLE....NVIRAGLKGt...psDKPTPLGSNMYIeygD.YS-.CNTsskp...................ltdmLKAAKDAVGSEAgsaepvegvnyldfyvvhnqphcnilrspllkggCDFWLRK.SELPGVLeraenftksipskvedrqaeekse...........tatereditnektpkfaealfrslPTACRYAFISAC...............................
B7Q125_IXOSC/30-189               ....................................................................................LGKYQDASAVF-.PLSETWYAAYRNYEDDPVFG-.TSKCLGFTEAQPEEDGGYPVvarygqesqsligqvEALNTRR..NIQAIWR.GC.NGVITLGTSEGY...NTK....NLIVLQPEG......QDQSLTLFVSYL...D.PGK.CGV...........................NRNLYVDET--A..................................CTVFVPE.SQLGKN-...........................................................TTCCDFVYDLLC...............................
B7PY25_IXOSC/32-182               ...................................................................................y-WQYQDIRRASL.NFNLKFWMMYRTLRRTD---R.ANECVYTEVKTQKTEDNAYE...............FVQGYMK..EDGTNVE.ETlLAFPYVTESAGHkkrEKE....NAMLVKKKE.....dAQNGKRYQLIYS...D.FKC.CDI...........................LRVLDEENG-AA..................................CELYLHD.KCVSQSV...........................................................PRQCESIYKNAC...............................
B7PAK0_IXOSC/31-170               .........................................................................qsfqdmskgfp------------.-LTETWYILYRNYEDDPVFGT.-DKCVRFNQENPATDGE---...............YPVTFKS..GE--DSE.PI.NTKIMLEPSEGY...TVT....NRIILSPEG......QSDTLTVYTAYM...DpDAK.CGV...........................TRNLYVSD--TA..................................CCVAVPE.SQLENQL...........................................................-ISCDFIYYLLC...............................
B7PQJ6_IXOSC/11-148               lqkyqdfkrgllygslvlvqssmkndsfrlcmmtykpntnltdegqidlltssrnstyremvqgfyaetarrhnrtyraiswlf------------.---------------------.--------------------...............-------..-------.--.------------...---....---------......RGEYYKSRVIFT...D.YKH.CII...........................LRTRTYNNL---..................................CELFTAG.RHDSNRV...........................................................NSWCFFIYTVFC...............................
B7PCP3_IXOSC/2-52                 ..................................................................ltledlfglstmkcyckl------------.---------------------.--------------------...............-------..-------.--.------------...---....--------G......APQPPLYKFMYI...N.SNKtCAV...........................LRATHQQNG---..................................-------.-------...........................................................------------tgs............................
B7PK15_IXOSC/4-130                ..................................................................................lq------------.---ETWYMLYRNYAFDPAFGG.TAKCVRFTNAGPEVNGAY-P...............LVISFGN..SSNS---.--.-VTATLGSSPGY...TAK....NIINLKSEA......QDTSLSVYDGYM...M.CKE.CAI...........................LRFPYANEN--A..................................CGLLVPE.SQLGQDI...........................................................-TCCRFVFDLIC...............................
B7QKR4_IXOSC/61-207               ...................................................................................k-YKEQNATRVL-.EMNATQWVKWRTYNVTEFLSNtPLECENFNITKKITPSN---...............YSLQYRY..RSGFDWK.TI.NENLILKEMGGH...GFP....NDMYFARTP......FGIPTDNLVLYS...N.YMS.CTI...........................LRIPFTNQGERH..................................CDLWMAN.MTLSQET...........................................................PDECLNRFFEYC...............................
B7QJ73_IXOSC/1-206                ..................................................................................vi-----------RnTENEAYYMVYVNEYNYN--YN.SKRCIQLRTSDLNQTLKTAV...............YNLTWNK..YDRWSQR.ME.EHQVAAIKQNNY...YQE....NILRFWYPDcg..srTADGSYNLVDYT...N.YQ-.CDSglrdptyfshde..eyydsyvvfsepsC----------Yilrtl........................ersgvCEFWLNE.ILLNKTLteleaqpeeesdkeknted.....................citesnaddklnlklfrklPRNCRVAFLLSC...............................
B7QNW8_IXOSC/114-209              ............................................................................rrpfirys------------.---------------------.--------------------...............-------..-------.--.------------...---....---------......-----EKYVIFS...N.SF-.CHI...........................LRALQNEEDYES..................................CEFWLRE.DWLKNVTipqvvtragseenekekk......................elgssskttylydslfkelPSSCRYAFLLNC...............................
B7PVD1_IXOSC/3-151                ............................................pqrevtspngtcynlnfnflcesggcrihhqecwqkrwtk------------.---------------------.--------------------...............-------..-------.--.------------...---....---------......---YSEKYVLFS...T.PL-.CYV...........................VRSLQDDEGYES..................................CEFWLNE.DWLKKNVtipqvvtilekedsdeiekseereesne...rkesvqceeeprtankttylydslfkelPSSCRYAFLLNC...............................
B7PEZ4_IXOSC/1-137                ...............................................................................qliet------------.--GEKQHIYYRSYDRDPLFGN.AGKCPYLMRRPRKQPPRPLK...............LIMGYQR..LN-SSLV.RF.KRPAEYQMSEDY...TVA....NMLWIKEGN.....hHNTTRRYTLVFT...N.NST.CSV...........................VRSDLGNG----..................................CEVWVPE.SALTQGP...........................................................SSCCNFLYHLLC...............................
B7PU25_IXOSC/1-86                 ...................................................................................m------------.---------------------.-------RYYEVLREKEKLL...............TQLLFRD..NSTGQMD.VY.TIVIVLEKSNKS..lGYY....DILVAQNDI......GTKYESYELLFT...D.YRT.CFT...........................LRRTSDDR----..................................YALW---.-------...........................................................------------...............................
B7PMR4_IXOSC/1-34                 .................................................................................mpg------------.---------------------.--------------------...............-------..-------.--.------------...---....---------......------------...-.---.---...........................-------QGQNH..................................CDLWMAN.MTVSQEP...........................................................PKICSDKFYEYC...............................
B7PLN8_IXOSC/39-193               ..................................................................................ye--KWQDINGALS.NSDSLSWMYVRTYQPEP-GDP.EYACVYAKVSRLPRKGQYI-...............FQQGWTQpdNTTIEVPlFV.NTTKTPGDGYTR...EKD....NAMHITLNIpq.lklYKDFGIYKLIYS...D.NEK.CDI...........................LRVTSKQQGYA-..................................CEMYLHS.SALKAGV...........................................................PPGCQSIYRHAC...............................
B7QBN6_IXOSC/2-132                ...............................................................................qcvpl------------.--KETWYSLYRNYETDPFFGG.TAKCGRFDVPSSAVNGTY-Q...............MSAQYG-..-----EI.SE.QVLLTLSSSEGY...DAG....NVVHFSKTG......EDASAVAYIAYD...N.CEE.CAI...........................VRNTYINE--KA..................................CVVFVPE.SALRKK-...........................................................KTCCDFVFDLLC...............................
B7QIW6_IXOSC/30-170               ...................................................................................l-GKYQNLDECF-.PLRETWITLYRNYPWDPVFGG.DATCIRESGTGPGVNGTY-P...............ILSQFGN..VSVK---.-A.TATFEASNGYTY...AGH....NILKLTPEG......GTDSIKIYIAYA...D.CEK.CGI...........................LRKTYATD--NA..................................CALLIPE.SQLGKN-...........................................................STCCDFIFDLLC...............................
B7P4F0_IXOSC/38-190               .............................................................iqrasfslisrdifaisgqpyya------------.--------------SAETVGS.EHTCVYAKVSENQPNGNVYE...............FVQKFRLgkEKTSPEQ.TV.TLYATPYKTEMH...ATErqndNAMLVSQKK.....dAQTGKGYQLIYS...D.YTQ.CDI...........................LRVLDESNGYA-..................................CELYLHS.NAVDGDV...........................................................PRKCESVYGNAC...............................
B7Q7M2_IXOSC/105-158              ..............................................................................ytvfye------------.---------------------.--------------------...............-------..-------.--.------------...---....---------......------TKVIYT...D.RKR.CTI...........................LRTPGYNNL---..................................CELFTSG.HYTSGSS...........................................................NSYCFFVYTMYC...............................
B7QAQ5_IXOSC/46-174               .............................................................................ytgtwha------------.--------KYRNFEHDKYFGA.TTKCVRVSHKETFKNGSTV-...............----HRV..E-VGSTV.KV.VIKIKLVSSEGY...THK....NTLHVSLKD.....lEEVSVDVSAAYI...D.CNV.CKV...........................LRHTYISK--TA..................................CSVLLPA.TQLHQP-...........................................................NTVCDFVYDLLC...............................
B7PR17_IXOSC/30-163               .........................................................ttrnnasrflntfkegyikyitvdigk------------.---------------------.--LCIAFTQTQFDATTKEAI...............YSV--SS..KSSSGTD.NP.TENQVFKVQECP...-SD....IDISLQSS-......GQPLYNITILYS...D.YSS.CHV...........................VQHRDETN---A..................................CSMFVKK.NARQFNI...........................................................-AACLPLYTRYC...............................
B7QAQ4_IXOSC/27-167               ......................................................................lgqfqdyeqcyplk------------.---GTWYLTYRTHEHDSFFGG.TAKCVRGHQVGPYENYTT-T...............IRVRHSP..N-----A.EI.DTRLHIKASEGY...THR....NVFTMTPVQ.....dPSKTEEFPIMYV...D.CSS.CWV...........................MRHPYVSN--RA..................................CSVAKKD.DHLGKN-...........................................................NLVCDFVYAVLC...............................
B7Q5U1_IXOSC/1-128                ...........................................mksrdywgdwvftnfscvsrwggrdrrpsdpirirfetkdy------------.---------------------.--------------------...............-------..--SGDVY.GH.QYEIKVLFYND-...KI-....DMFSYDSWR......QGKVQTRQLIYM...N.LTEqCQV...........................TKTFSDKGNPLG..................................CTMWMGY.YKVDGNP...........................................................PKECEEVYTN--cg.............................
B7QIW7_IXOSC/36-174               ....................................................................................LQQYQDLTKCF-.PLQESWHTIYRNYESDPAFGG.TTKCVKYTENGPPVNGA---...............----YPL..RFDFGSQ.SA.TASGSLESSPGY...TGK....NILNLTPAG......GSTTVQVYAAYV...E.CAQ.CVV...........................FRNTYVSD--AA..................................CTLLVPE.SELNKNI...........................................................-TCCDFIFDLLC...............................
B7QNW8_IXOSC/1-122                ..................................................................................mt------------.--NQSYYLVYSNGWGTQEHYQ.DVTCLQVQTSDLNYTLKSAQ...............YTSKWYN..TKSKTMV.SS.TQYVQAVKQKDY...SIE....NIMYLGQPQrk..atSPNGTCYNLDFNflcE.ANG.CII...........................------------..................................-------.-------...........................................................------------yhqecwrrpfiryse................
B7QC28_IXOSC/2-76                 ...........................................................................rataqpspk------------.---------------------.--------------------...............-------..-------.--.------------...NET....NIIRFSNADlcnqgtDSLFAEYEVLYS...N.YES.CFV...........................LTLLSTEE--KR..................................CELWVK-.-------...........................................................------------ggfevhfenephe..................
B7PBP1_IXOSC/27-95                .................................................................................pts----KGAWKLF-.LKPQKFYLLYRSEKNDTKLGG.ESKCFQMKYYEADPEKKEFL...............THLLFRN..DTTGHMY.--.------------...---....---------......------------...-.---.---...........................------------..................................-------.-------...........................................................------------vhff...........................
B7QBN5_IXOSC/2-137                ...........................................................................khtlqclpl------------.--QEKWYTLYRNYESDPAFGG.TDPCIEFTCLGPAVDGA-FT...............FTVRYGD..S------.SA.NLTLTLSASEGY...TTQ....NLLHFQPIG.....rKLFSMLLTASYV...D.CMT.CVV...........................FRSTYLNEG--A..................................CSLIVPE.SALGKEL...........................................................-SCCDYLFDLLC...............................
B7QMG6_IXOSC/2-53                 ................................................................................gekv------------.---------------------.--------------------...............-------..-------.--.------------...---....---------......----SQAVILYS...N.FDS.CTI...........................FFNIEQQE----..................................CQLWAYE.NPTNDVI...........................................................-QECLETYKTLC...............................
B7PA76_IXOSC/31-169               ........................................................................qeyqnegpcfpl------------.--EETWYVAYRNYETDPIFGG.SAKCVRFSETDPGQNGAY-P...............VIVEYEP..NFS----.-A.DLTVTLSSSPGY...TLK....NILNFQPQG......QSMSVPAYSAYK...D.VKK.CDV...........................LRTTYA--GDDA..................................CVLLVPK.SQLGHH-...........................................................EMCCDFIFDLLC...............................
#=GC seq_cons                     ...................................................................................h...................hhhaps...p......t.pCh.hp..t...s.t......................a..................h.h..t.t....t......Nhh.ht.........tt.sh.hhlhY....s.hpp.Ctl...........................lRth..pp......................................Cphhh.p.ptlttt.............................................................ptC..ha...C...............................
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