#=GF ID Htr2
#=GF AC PF17909.5
#=GF DE Htr2 transmembrane domain
#=GF AU El-Gebali S;0000-0003-1378-5495
#=GF SE ECOD:EUF00795
#=GF GA 25.00 25.00;
#=GF TC 34.50 52.90;
#=GF NC 22.10 21.70;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP Domain
#=GF RN [1]
#=GF RM 28165484
#=GF RT New Insights on Signal Propagation by Sensory Rhodopsin
#=GF RT II/Transducer Complex.
#=GF RA Ishchenko A, Round E, Borshchevskiy V, Grudinin S, Gushchin I,
#=GF RA Klare JP, Remeeva A, Polovinkin V, Utrobin P, Balandin T,
#=GF RA Engelhard M, Buldt G, Gordeliy V;
#=GF RL Sci Rep. 2017;7:41811.
#=GF RN [2]
#=GF RM 23619282
#=GF RT Ground state structure of D75N mutant of sensory rhodopsin II in
#=GF RT complex with its cognate transducer.
#=GF RA Ishchenko A, Round E, Borshchevskiy V, Grudinin S, Gushchin I,
#=GF RA Klare JP, Balandin T, Remeeva A, Engelhard M, Buldt G, Gordeliy
#=GF RA V;
#=GF RL J Photochem Photobiol B. 2013;123:55-58.
#=GF DR INTERPRO; IPR040913;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC Archaebacterial photoreceptors mediate phototaxis by regulating
#=GF CC cell motility through two-component signaling cascades like
#=GF CC those found in chemotaxis signaling chains of enteric bacteria.
#=GF CC The photoreceptor sensory rhodopsin II from N. pharaonis
#=GF CC (NpSRII) in complex with its cognate transducer NpHtrII serves
#=GF CC as a system for transmembrane signal transfer. This entry is for
#=GF CC the transmembrane domain of the transducer HtrII. Studies
#=GF CC suggest that conformation changes of the NpSRII/NpHtrII complex
#=GF CC may be crucial for the mechanism of signal propagation spanning
#=GF CC the membrane domain and feeding into the HAMP domain [1].
#=GF CC Furthermore, HtrII in H. salinarum not only transmits the signal
#=GF CC from the photoreceptor SRII but also operates as a chemoreceptor
#=GF CC [2].
#=GF SQ 8
#=GS M0LKB6_HALLS/21-84 AC M0LKB6.1
#=GS A0A2Z2HYI9_9EURY/21-81 AC A0A2Z2HYI9.1
#=GS A0A346PLV0_9EURY/21-81 AC A0A346PLV0.1
#=GS L0AGQ4_NATGS/21-80 AC L0AGQ4.1
#=GS A0A4S3TLK5_9EURY/21-84 AC A0A4S3TLK5.1
#=GS A0A1U7EZ33_NATPD/23-83 AC A0A1U7EZ33.1
#=GS F8DBF1_HALXS/21-81 AC F8DBF1.1
#=GS A0A6B0T1V1_9EURY/21-81 AC A0A6B0T1V1.1
M0LKB6_HALLS/21-84 ...GAIFALVIAVTVAFGGAVYLEITAAIAEanaGGD...ANVGEVAVSAILGLIVLTVINLGLVASTVG
A0A2Z2HYI9_9EURY/21-81 ...GAIFTLVTIVTLAFGGVAYGDVAAALET...GDA...TAVAGASTSAILGLIVLTVINLGLVAATVG
A0A346PLV0_9EURY/21-81 ...GTTFTLVVAVTLAFGWAMNAEVVAAVET...GEA...AAVGDAATSAILGLVVLTVINLGLVAATVG
L0AGQ4_NATGS/21-80 ...GAIFALVIAVTIGFGGAVYLEITAALAD...-DP...AVVGEVAVSGILGLIVLTVINLGLVAATVG
A0A4S3TLK5_9EURY/21-84 ...GTIFALVIAVTVAFGGAVYLEITAAIAD...ANAgadATVGAVAVSAILGLIVLTVINLGLVAATVG
A0A1U7EZ33_NATPD/23-83 ...GATFAFVGALTVLFGAIAYGEVTAAAAT...GDA...AAVQEAAVSAILGLIILLGINLGLVAATLG
F8DBF1_HALXS/21-81 ...GAIFALVIAVTLAFGGAAYLEVAAALES...GDA...AAVGEAATSAILGLLVLTVINLGLVAATVG
A0A6B0T1V1_9EURY/21-81 gvg---FVQILVVTAIFGAAISAELATAAET...GDV...GAVRDVAFSGFLGLILLTVINLGLFAATVG
#=GC seq_cons ...GAIFALVlAVTlAFGGAsYhElsAAlto...GDA...AAVG-sAsSAILGLIVLTVINLGLVAATVG
//
