#=GF ID   IFS
#=GF AC   PF16718.9
#=GF DE   Immunity factor for SPN
#=GF AU   Eberhardt R;0000-0001-6152-1369
#=GF SE   PDB:3qb2
#=GF GA   30.00 30.00;
#=GF TC   30.20 68.30;
#=GF NC   26.60 23.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   21300288
#=GF RT   Structural basis of Streptococcus pyogenes immunity to its NAD+
#=GF RT   glycohydrolase toxin.
#=GF RA   Smith CL, Ghosh J, Elam JS, Pinkner JS, Hultgren SJ, Caparon MG,
#=GF RA   Ellenberger T;
#=GF RL   Structure. 2011;19:192-202.
#=GF DR   INTERPRO; IPR032002;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   Immunity factor for SPN (IFS) binds to and inhibits the SPN
#=GF CC   toxin [1].
#=GF SQ   7
#=GS Q9A1P6_STRP1/1-118        AC Q9A1P6.1
#=GS G5K2H9_9STRE/1-161        AC G5K2H9.1
#=GS A0A1D9P328_9FIRM/8-144    AC A0A1D9P328.1
#=GS A3CNH2_STRSV/5-171        AC A3CNH2.1
#=GS C8NIT4_9LACT/5-171        AC C8NIT4.1
#=GS G5KD06_9STRE/1-161        AC G5KD06.1
#=GS A0A1D9P328_9FIRM/168-324  AC A0A1D9P328.1
Q9A1P6_STRP1/1-118                   ............-------------------------------------------MEDISDPEVILEYGVYPAFIKGYTQLKANIEEALLEMSNSGQALDIYQAVQTLNAENMLLNYYESLPFYLNRQSILANMTKA---LKDAHIREAMAHYKLGEFAH...YQDTMLDMVERTIKTF........................
G5K2H9_9STRE/1-161                   ............MYKIPKGLEDYQKIFQEERSLKEFITFFIGKDKNYRITKRDSYMGDISDPEVILEYSIYPLYIKGKTQLKEKVEEALLEMSKSGKALYIYQVVQFINGENMLLNYYEELPFYLNRDQILSHVKQA---LADDHIRQEMKTYKTGEFAH...YKDTMLDMVERIMDTF........................
A0A1D9P328_9FIRM/8-144               innfesqewaeq-------------RVLNAVKCGCLKLVIYGAVPDYRINNRYSYYQDLTDAEDLIRYGLYPVYLKYGLNIDELTRKAIEEMIENGSEREVSQAYDYIMSELSNREDYSNLPFSIVDKELIYKLKDRLKK--------------------...----------------dnsdmgkdwn..............
A3CNH2_STRSV/5-171                   ...........e-LPEPKDYQSFINFYRNVMREGREEEAFLGTNPKYRIWQRDSYELDSTDIGVLIEYCLFPLYAEGDRDIARRNFDILKEFSLSNDLMKLKKVTQYISNQKWFVTNYYDIPFVIETDELVRNIIESTSHLSDDQKRTYTYEGLCNVLDRnllYRQCDEEKVEKILKEF........................
C8NIT4_9LACT/5-171                   ...........e-IPEPKEYESFVNFYRDTMREGKEEEAFLGTNPKYRIWQRDSYELDSTDILVLMEYCLYPLYMEGDREIARRTFDILKEFSLSNDLMRLKKVTKYISIQSRWVKKYTSLPFVIETDELVRNIIESISKLSDEQKRTYTYERLCNVLDHsplYRQCDEEKVEKILKEF........................
G5KD06_9STRE/1-161                   ............MYNCPSGYEKYIPLFNKTLDKETLTRYFVGQDKKYRLNNRESLMSDISDTEFILEYCLYPVFLQGKTDIKDLTQETLLNMSTSNDPIQIYQALLFLNSQNMLLQYYEAVPFIIEQEPILSNIKKA---IDDTALVNKMKTYQVGEFAQ...YKDSLFDMLERVLQTF........................
A0A1D9P328_9FIRM/168-324             .....vpyddek---------DVMNRIMEAINDGHFVDLMIGEKEEYRVRSSDSQ-TSYTDMYDLINNGLYPLYLSGMHEIKEMTRNAIETMVDSGNPIALFQVYDYISKEVFVIENCCNYPFSILDKELISRIKRK--RIDMEEILKYT----------...----------------avdnktvweraeqrekmrvfsdtd
#=GC seq_cons                        .....................ph..hh.pshpptp..phhlGps.cYRl.pR-Sh.tDhoDhtsllEYsLYPlYlcGtppIcchsp-sLhEMSpSss.hplhQshpaIsspshhlp.YpslPFhIppcpllpplpcu...lsDpphhphhhph.hs.hsp...Ypps..-hlE+hhppF........................
//