#=GF ID   ITPK1_preATP-grasp
#=GF AC   PF21512.1
#=GF DE   Inositol-tetrakisphosphate 1-kinase, preATP-grasp domain
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF AU   Chuguransky S;0000-0002-0520-0736
#=GF SE   ECOD:EF16161
#=GF GA   27.00 27.00;
#=GF TC   30.80 203.90;
#=GF NC   25.60 17.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP   Domain
#=GF CL   CL0063
#=GF RC   Paper describing PDB structure 1z2n
#=GF RN   [1]
#=GF RM   15837423
#=GF RT   Specificity determinants in inositol polyphosphate synthesis:
#=GF RT   crystal structure of inositol 1,3,4-trisphosphate 5/6-kinase.
#=GF RA   Miller GJ, Wilson MP, Majerus PW, Hurley JH;
#=GF RL   Mol Cell. 2005;18:201-212.
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   Inositol-tetrakisphosphate 1-kinase (ITPK1)  can phosphorylate
#=GF CC   various inositol polyphosphate such as Ins(3,4,5,6)P4 or
#=GF CC   Ins(1,3,4)P3. Phosphorylates Ins(3,4,5,6)P4 at position 1 to
#=GF CC   form Ins(1,3,4,5,6)P5 which may play a regulatory function. It
#=GF CC   may also act as an isomerase. This entry represents the
#=GF CC   preATP-grasp domain [1].
#=GF SQ   1
#=GS ITPK1_ENTH1/5-91  AC Q9XYQ1.1
ITPK1_ENTH1/5-91             QTVSLFIWLPESKQKTLFISTKNHTQFELNNIIFDVTLSTELPDKEPNAIITKRTHPVGKMADEMRKYEKDHPKVLFLESSAIHDMM
#=GC seq_cons                QTVSLFIWLPESKQKTLFISTKNHTQFELNNIIFDVTLSTELPDKEPNAIITKRTHPVGKMADEMRKYEKDHPKVLFLESSAIHDMM
//