#=GF ID Imm64
#=GF AC PF15600.10
#=GF DE Immunity protein 64
#=GF PI Imm39; Imm39_;
#=GF AU Zhang D;0000-0001-8535-7620
#=GF AU de Souza RF;0000-0002-5284-4630
#=GF AU Anantharaman V;0000-0001-8395-0009
#=GF AU Iyer LM;0000-0002-4844-2022
#=GF AU Aravind L;0000-0003-0771-253X
#=GF AU Finn RD;0000-0001-8626-2148
#=GF SE [1]
#=GF GA 25.00 25.00;
#=GF TC 25.50 30.00;
#=GF NC 23.50 23.10;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 22731697
#=GF RT Polymorphic toxin systems: comprehensive characterization of
#=GF RT trafficking modes, processing, mechanisms of action, immunity
#=GF RT and ecology using comparative genomics.
#=GF RA Zhang D, de Souza RF, Anantharaman V, Iyer LM, Aravind L;
#=GF RL Biol Direct. 2012;7:18.
#=GF DR INTERPRO; IPR028951;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC A predicted immunity protein with an alpha+beta fold and a
#=GF CC conserved DxEA motif and arginine residue. Proteins containing
#=GF CC this domain are present in bacterial polymorphic toxin systems
#=GF CC as an immediate gene neighbour of the toxin gene, which usually
#=GF CC contains toxin domains of the Tox-ColD family [1].
#=GF SQ 17
#=GS F5LRH0_9BACL/1-189 AC F5LRH0.1
#=GS A0A1B8UJD8_9BACL/1-189 AC A0A1B8UJD8.1
#=GS W9DTL0_METTI/1-207 AC W9DTL0.1
#=GS A0A2N0ZBS5_9BACI/3-193 AC A0A2N0ZBS5.1
#=GS A0A0C1R5N6_9CLOT/1-200 AC A0A0C1R5N6.1
#=GS A0A6B3VX78_9BACI/1-190 AC A0A6B3VX78.1
#=GS A0A6G7X0S7_9FIRM/8-182 AC A0A6G7X0S7.1
#=GS A0A6G7Y151_9FIRM/3-184 AC A0A6G7Y151.1
#=GS E7FY67_ERYRH/10-184 AC E7FY67.1
#=GS B8I7J1_RUMCH/1-195 AC B8I7J1.1
#=GS Q8TP73_METAC/4-210 AC Q8TP73.1
#=GS A0A371J2H1_9FIRM/1-195 AC A0A371J2H1.1
#=GS A0A6G7Z9B8_9FIRM/5-185 AC A0A6G7Z9B8.1
#=GS A0A7G9S0W5_9FIRM/46-186 AC A0A7G9S0W5.1
#=GS A0A7R7EHQ4_9FIRM/1-194 AC A0A7R7EHQ4.1
#=GS A0A7V7UBK9_9FIRM/1-195 AC A0A7V7UBK9.1
#=GS A0A1G7VJE4_9BACL/1-189 AC A0A1G7VJE4.1
F5LRH0_9BACL/1-189 ....................................................................................................MGSYINIG-----------LIYS--SSEATEAHLMKLIELLTENEGRIENVKFCEDVDGERWIQYDFPHHDP--AIFEKLT.RSYYGHIYLFADLVPFKGLNVEIEIE.KCE.G..YSGFLVSFRESEM.LPDYS..ADSLETATETLVKLVAEIYPAVPFDYAFCDLEAQIEFSPQEFK---PERYSLSFWP..DISNGELKVTKSNCHINGLTER
A0A1B8UJD8_9BACL/1-189 ..................................................................................mgasinvgliycneldvf------------------------------SKRLYSIMDFLVSSQGEILSMKYALDEDALNWVETGTCRS-VDSNLINELL.QNYFAEISINTGSLFVNSKNICISVE.KNEgH..HSGVIISFQESEI.IVDYS..IEELDSATDFMVDFIKQVYQIAPFDFAFCDHEAEIIYPLNGVE------YSIMIYP..TSVASDILVEKSNWHLNGLTKR
W9DTL0_METTI/1-207 ....................................................................................................MGARISIGLTYGIG-NLKTLVYDDATVEKLQQELKNIIGYFLDSNGTIKVAKYSENADGENWKEINLDSLFFSLENLKDFS.SGYYGEILLNSEIIKGKKLDYTIRTV.KET.N..FFGFLLDIEEADI.FKSTSypDEEIDSITEKLITTMCRIYSHSKYDYAFCDLEAQFYYPLEIFKHSDGYIYSVTIIP..NSDSN-LTVIKSDWHIDGHNAR
A0A2N0ZBS5_9BACI/3-193 .......................................................................................atmnvifvksdls----------------------------TLKNNFSSLLNYFLNNSIGFSSLHISNDEEGFNGIDYNNPNQTFLENIMDKSP.DFYYLKLSFNNFPFGNLFIDGLLKIE.KHEnS..YYSFGFEFEEVDI.LSNYD..VDSLESVEKNIINTIEKIGENINWDYAFANQEAEVQFSPEQFEKETNTQYAIEITN..--SESGLKISKSTWYVNGITER
A0A0C1R5N6_9CLOT/1-200 ....................................................................................................MGSSISIG-----------FVYGEFSIQAIENEIKRLVKYFVTTDGSLKKMKVSKDIDGEEWLEYDSLINLKVDSIYTTLA.ENYYGQVEVNSSLFGHKNLTTTIRIE.KEE.DegYFGFLLDIDEEEL.IKTNL..ASEINSVTEKIVDFITGFYSYSAYDYAFCDNEAEIQYSPRHFKKIESSIYSISVIPtlDGNSNSLNIVRSNWNIDGLTSR
A0A6B3VX78_9BACI/1-190 ...................................................................................................m-GSNISLG-----------IVYASNQLANAENITRNVSNLFVSDDGYIKSFKYSTDLQGTKWKEFSGINSELAKSMYSSLI.NSYYGSITIMSNLFNEKLKEMVISIE.VTN.E..YFGFLVDIKEELL.EGIN-..---LDELEENIINFFMKNYECLKFNYAFCDHEAEIEFSPDEIAHMTDEVYSILLLQ..--VNNELVLEKSSWKIDGLTER
A0A6G7X0S7_9FIRM/8-182 givlkndinitkelenffdfleiyvhqiqvnfpeegdyedweekilvdnyvqlidllafrgayasfdlefnhehfatrlslsnegddlvvhlalhhpfek---------------------------------------------------------------------------------.--------------------------.---.-..-------------.---RD..IQSLELLTQGIASFIDTIDTHVVHDYIFCDNEAEYLYKKERMLELGYNPYAILKLH..DR-----MLVQAAWYLDGFTER
A0A6G7Y151_9FIRM/3-184 .........................................................................................tyiglgvvlkn--------------------------DESLANELENIMDLLENHAQEI-VVTYPKDGDLNDWQHEAIEGRLY--DVIDYLTyRTSYADMMLD---LGGRVVEARLSLT.NES.D..VAVMKLEIADKGM.FKDRT..LEDLEAVTSILTDFIEAIDRSVTYSYIFCDNEAEFLYTKERLLEVGYNPYAILKMH..DRTT-----AYAAWYVDGFTER
E7FY67_ERYRH/10-184 ......................................................................................vleasdktigqien------------------------------------ILD-LVDSYKTKMEITHPKDGDYHDWITETVDGNIY-TTIEKLAY.RTSYADIEFK---IGNKDVETRMSIT.NET.D..ALVVKFDIVEEHL.LPEKS..VEHLEATTQLMTHIFEIIDRNVEYEYLFCDSEAEYLYSKQRLLEVGHQPYALFKMN..DRNT-----VYAEWYLDGFTLR
B8I7J1_RUMCH/1-195 ....................................................................................................MGSYIGIG-----------FVYNGMSGERVEIELKNIVNFLISHNGNINSIKFSKDEYGNVWIQDSLNNKCI-DDFYSSLC.NGYFGELHITCSILSVQNLNVCIRIE.KAK.K..YFGLLLDISEEEL.IGVNS..SENINRITEEIIEFFNELYKASVFEYAICDNEAEIQYSPEEFQSIGEAVYSIAALP..EKNKKSLKIIKNSWHIDGLTAR
Q8TP73_METAC/4-210 ....................................................................................................MGSYISIGLTYGIVQRFANLVYDDATNNKIEKELKKLIEYFLDSDGIIKNIKYSEDLEGEHWKEVNSPSPFFPRDCYKSFS.RGFYGEVAVHADILKRRGVDLIMRLE.KQS.E..FFGFLLDIKEEDL.LETHS..KEEIGYMTEELIDTMMSIYKYSKYDYTFCDQEAEFKYSLSSLKKLKEDVYSIVIIP..DSDNNSFTVIKSDWNIDGLTGR
A0A371J2H1_9FIRM/1-195 ....................................................................................................MGSYINIG-----------IVYTDKNIIKMDDDFVIVIKYLSPFCNKI-VVKYPKDDAFENWEEKSFEGEEGFVEAFSILN.EKNFSTGKIYCKIQNKQ-YNILVSIKgKND.L..FRGILFEIPEEELfLENSS..SDNLSLTTNKIANSIIELWNNTEFNYAFCDSEADIEYSLCEVRESEKPIYSMLLLK..NEFNQPI-VRLGSWCIDGLTPR
A0A6G7Z9B8_9FIRM/5-185 .................................................................figlgivienddnlmieventldllneyadnimlt----------------------------------------------------YPHEGNTDDWRTDSFEGKLN--EMIEGLSyRTAYADMEL---ILGNEVYEARLSMS.NEG.T..VTVLKFEISDRDV.FHDRT..FEDLERVTQIFTEFIRTIDRNVHHSYIFCDNEADFLYKKERLIEVGYNPYAIIKMG..DRD-----VAYAAWYLDGFTER
A0A7G9S0W5_9FIRM/46-186 ...............................................................ddwveepvqstddmnliveklayktsyadinlemgdy---------------------------------------------------------------------------------.-----------------NLETRLQLS.NEE.K..DFLVHFEIDQASL.IRDNS..RESLEKATSLIKSLIQSIDEAVDYSYIFCDQEAQYLYTKSRLIEIAHNPYAILKMH..ERE-----IVQAPWYLDGFTLR
A0A7R7EHQ4_9FIRM/1-194 ....................................................................................................MGSYISVG-----------FIYDKISIDNIKNKMKSLIDFIVSKKGEIKRAKICKDIYGDEWIEYELNDNTQIDNMLVLLA.EHYFGQIEIETNLFDLMNLDITVHVE.KEE.G..YFGFILDISESAF.Y-KDS..LNMVNSYTDKFIDLMKKFYKCSAYNYAFCDNEAEIKYSPLAFRNLNKRVYSLAILP..VHNN-NLRVIKSEWNIDGITNR
A0A7V7UBK9_9FIRM/1-195 ....................................................................................................MGSFISIG-----------IVYTDKNIIKMGDDLVDIIKYLSPFCNKI-VVNYPDDDICENWEEKSFVGEEGFEKAFSILN.DKKFSTGKIYCKIQ-NKDYNVLVSIKgKND.L..FRGILFEIPEEELfLEKFS..SDILDIITDKIANSIIELWNNTEFNYAFCDSEADIEYSLCEVRASEKPIYSMLLLK..NEFNQPI-VRLGSWCIDGLTPR
A0A1G7VJE4_9BACL/1-189 ...................................................................................................m-GSTINIG-----------LVYNDS--KAIGKILEKLLGLVVENNGHFQSVKFCEDYDGESWIELDYPNMD--TTFIDKMT.KSYFVQIQSCLDLFQIEQLKTDIRIE.KYD.E..FFGLLLLFNEDEI.LPNYS..IESLEKITNSIINFIVEVHPVLNFDYAFCDHEAEIEYSPKEFKP---EKYSLSFLP..NLTNGVLGVRKSSWEINGLTER
#=GC seq_cons ................................................................................................................................thtpph.pllphhhsppspl.sh+ascD.psppWhchsh.sp.h..shhp.hs.cshauplpl.stlht.pslphplplc.Kpp.p..ahGhlh-IpEp-l.ltspS..h-pL-phTpplhshlpplapsspasYAFCDpEAEh.YS.pchpc.ttp.YSlhhhs..spsst.l.lhpusWplDGlTtR
//
