#=GF ID Imm72
#=GF AC PF15584.10
#=GF DE Immunity protein 72
#=GF PI Imm44; Imm44_;
#=GF AU Zhang D;0000-0001-8535-7620
#=GF AU de Souza RF;0000-0002-5284-4630
#=GF AU Anantharaman V;0000-0001-8395-0009
#=GF AU Iyer LM;0000-0002-4844-2022
#=GF AU Aravind L;0000-0003-0771-253X
#=GF AU Finn RD;0000-0001-8626-2148
#=GF SE [1]
#=GF GA 25.00 25.00;
#=GF TC 26.00 30.40;
#=GF NC 24.30 18.50;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 22731697
#=GF RT Polymorphic toxin systems: comprehensive characterization of
#=GF RT trafficking modes, processing, mechanisms of action, immunity
#=GF RT and ecology using comparative genomics.
#=GF RA Zhang D, de Souza RF, Anantharaman V, Iyer LM, Aravind L;
#=GF RL Biol Direct. 2012;7:18.
#=GF DR INTERPRO; IPR028966;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC A predicted immunity protein with a mostly all-beta fold and
#=GF CC GxxE, WxDxRY motifs and a glutamate residue. Proteins containing
#=GF CC this domain are present in bacterial polymorphic toxin systems
#=GF CC as an immediate gene neighbour of the toxin gene, which usually
#=GF CC contains toxin domains of the Ntox48 family. This domain is
#=GF CC often fused to the Imm71 immunity domain [1].
#=GF SQ 35
#=GS I2B702_SHIBC/189-298 AC I2B702.1
#=GS B2JM84_PARP8/202-284 AC B2JM84.1
#=GS A0A8A8D1T5_9BURK/192-287 AC A0A8A8D1T5.1
#=GS A0A1G6H7N2_9BURK/165-247 AC A0A1G6H7N2.1
#=GS A0A840MIS2_9PROT/215-318 AC A0A840MIS2.1
#=GS C5A990_BURGB/215-295 AC C5A990.1
#=GS I2B701_SHIBC/189-298 AC I2B701.1
#=GS A0A2S5ST00_9BURK/193-305 AC A0A2S5ST00.1
#=GS A0A1H7P9R3_9BURK/192-294 AC A0A1H7P9R3.1
#=GS Q5GVQ4_XANOR/191-290 AC Q5GVQ4.1
#=GS A4JC59_BURVG/216-296 AC A4JC59.1
#=GS A0A4Q4XBN7_9PEZI/674-771 AC A0A4Q4XBN7.1
#=GS A0A2U2HFL0_9BURK/200-280 AC A0A2U2HFL0.1
#=GS A0A7Z2GQC1_9BURK/215-295 AC A0A7Z2GQC1.1
#=GS A0A0H3KFL3_BURM1/48-142 AC A0A0H3KFL3.1
#=GS A0A1N6X4F0_9RHOO/193-295 AC A0A1N6X4F0.1
#=GS Q05HT6_XANOR/1-46 AC Q05HT6.1
#=GS A0A562RLB4_9BURK/174-275 AC A0A562RLB4.1
#=GS A0A1N6X4K7_9RHOO/190-294 AC A0A1N6X4K7.1
#=GS I2B6Y7_SHIBC/189-298 AC I2B6Y7.1
#=GS A0A1H8DGX6_9BURK/149-250 AC A0A1H8DGX6.1
#=GS A0A0H3KJI5_BURM1/41-139 AC A0A0H3KJI5.1
#=GS A0A1N6KVC4_9BURK/214-294 AC A0A1N6KVC4.1
#=GS A4J9U7_BURVG/212-307 AC A4J9U7.1
#=GS A0A4S3K5B4_9GAMM/190-290 AC A0A4S3K5B4.1
#=GS A0A0N1B6X7_9PROT/178-280 AC A0A0N1B6X7.1
#=GS A4JC60_BURVG/215-295 AC A4JC60.1
#=GS A0A0H3KB63_BURM1/181-276 AC A0A0H3KB63.1
#=GS A0A2R4CB54_9BURK/193-292 AC A0A2R4CB54.1
#=GS Q5GX25_XANOR/11-110 AC Q5GX25.1
#=GS B2JM82_PARP8/203-285 AC B2JM82.1
#=GS A0A7Z2GPJ0_9BURK/192-291 AC A0A7Z2GPJ0.1
#=GS A0A0H3KB55_BURM1/38-133 AC A0A0H3KB55.1
#=GS A0A4Q4WAH1_9PEZI/6-36 AC A0A4Q4WAH1.1
#=GS I2B6Z8_SHIBC/189-298 AC I2B6Z8.1
I2B702_SHIBC/189-298 ................PVPERRDIIIKTDDPVPCDGIWEPVNIlynhkfl..................vikdgisgFKNLG..AYNYFIRGMKApr..qiyYDVLMESdke.......mliTDDp.irYRDV.....HWRLVWEDTRYCDGIIPDESEYFL...
B2JM84_PARP8/202-284 ................PRNEDNTGEVWSGRQIPVTGIWEPWAI.................................NPKIGvrCPNYYLVGDTA.......SQYQFEG.............TDT....LEDV.....RWRLIWKDSRYASGQTPYEEDEYF...
A0A8A8D1T5_9BURK/192-287 ..............ev--PEPVGTVIRSGEKVPCDGIWEPVAVeqskllg..................ivpvgdrsLHGNG..CFNYLIRDIRA.......PNLRDDD.............ARV....PVKT.....HWRLLWEDKRYADGIIPDESQYFL...
A0A1G6H7N2_9BURK/165-247 ................PRNEDNMDEVWSGREIPVTGIWEPWAI.................................DPKIGvrCPNYYLAGDIA.......SQYQIEG.............TDT....LEDV.....RWRLIWKDLRYPSGQTPVEEDDYF...
A0A840MIS2_9PROT/215-318 ...........vpvpk-----EEVLVKTGHTLPCTGIWEPVKVdlsagflglf.............qrpqipadgvFEPDG..CMNYLHGGARA.......PTVEFEE.............EKWp.ivGKPT.....VWRLLWKDERYLDGTVPDEEKDY-v..
C5A990_BURGB/215-295 ................PKNESSTGEVNSGEEIPVEGIWEPWFP.................................GDEVG..CPNYFLKGSIA.......HQYLLEG.............TND....EYDV.....RWRLLWEDTRYQGGSIPEEESTYF...
I2B701_SHIBC/189-298 ................PVPERRDIIIKTDDPVPCDGIWEPVNIlynhkfl..................vikdgisgFKNLG..AYNYFIRGMKApr..qiyYDVLMESdke.......mliTDDp.irYRDV.....HWRLVWEDTRYCDGIIPDESEYFL...
A0A2S5ST00_9BURK/193-305 ............vplp-----SDLTVNTGEEVPVDGIYEPEWGepvqpdpglwarvqaalgvrpslyepapqplvrRRHIG..CMNYLVAHTVA.......PTYRDEE.............RDK....PWPV.....TWRLIWKDERYLDGTVPEEEAQYL...
A0A1H7P9R3_9BURK/192-294 ..........papvdn-------QFVRTNDYVPCSGIWEPVEApplaksllrs............lftrpdepqapFNIAG..TINYLHGGSKS.......PQITVET.............GDD....SQDId...tVWRLLWRDERYTNSPVPEYEAGY-r..
Q5GVQ4_XANOR/191-290 ...........pnpve------NTLIATGTRIPCSGIWEPVDApkpkkfslf...............skpevpkgfLPYIG..ALNYLHEGSPA.......PQAGQIF.............VDKs..iDIDV.....VWRLIWRDDRYEDGTIPDEEAEY-v..
A4JC59_BURVG/216-296 ................PKNESAAGEIHSGQEIPVEGIWEPWFP.................................AGKVG..CPSYFLKGSIA.......HTYLLEG.............TND....EHAV.....AWRLLWEDKRYRGGSIPAEEAAYF...
A0A4Q4XBN7_9PEZI/674-771 .............pdp----KEDVLVYSGKMTPYSGIWEPVDApkpkllslf...............rndeqpkgsFPIVG..TMSYLHGGSNA.......PNMAAYA.............EER....GLPT.....TWRLLWRDTRYEDGTIPNEERDY-v..
A0A2U2HFL0_9BURK/200-280 ...........pipea------EVLIETGKELPVFGIYEPQI-.................................--KDG..CMNYLFGGALA.......PT-LWDSdg........iylTGR....KLSV.....IWRLIWEDKRYLDGSIPVEERLYF...
A0A7Z2GQC1_9BURK/215-295 ................PQNESNGAEVNSGQEIPVEGIWEPWLA.................................EGKVG..CPNYFLKGSIA.......HPYLLEG.............SND....ERPV.....RWRLLWEDDRYRGGSLPAEEAAL-f..
A0A0H3KFL3_BURM1/48-142 ........evpngagp--------VISSGDKVPCDGIWEPVAIeqskllg..................ivpvgdrsSRNNG..CFNYFIRDIRA.......PN-LRDA.............TGA....VTGT.....RWRLLWEDRRYADGTVPDESQYFL...
A0A1N6X4F0_9RHOO/193-295 .........plaepar--------LIKRGDLVPCSGIWEPVRVdfsegflglf.............rkpmippgarLPLDG..TMNYLHGGSPA.......PNISFEGd..........tpRDD....GRPT.....VWQLLWRDDRYEDGTIPDEEAGY-t..
Q05HT6_XANOR/1-46 mggsaapkarqetqag---------------------------.................................-----..-----------.......-------.............-SV....HPDV.....VWRLIWRDDRYEDGTIPDEEAGY-v..
A0A562RLB4_9BURK/174-275 .........dpaeplf---------VYTGRVPPCSGIWEPVAVpprkltlrsl............lliapppppppFCVVG..AMHYLHGGLVA.......PHAPVST.............GEEi..dCVDV.....AWRLLWRDERYRDGSVPATESSY-r..
A0A1N6X4K7_9RHOO/190-294 ........pvpraepa-------QLIKSGDLVPCSGIWEPVRAdfsegflglf.............rkpmippgarLPLDG..TMNYLHGGSPA.......PNISFEGd..........spRDD....GRPT.....VWQLLWRDDRYEDGTIPDEEAGY-t..
I2B6Y7_SHIBC/189-298 ................PVPERRDIIIKTDDPVPCDGIWEPVNIlynhkfl..................vikdgisgFKNLG..AYNYFIRGMKApr..qiyYDVLMESdke.......mliTDDp.irYRDV.....HWRLVWEDTRYCDGIIPDESEYFL...
A0A1H8DGX6_9BURK/149-250 .........pvpepaa------PIFVRANGRASCAGIWEPVAApassflsrf...............tgswkpqppLEIVG..AMAYFTPYSTA.......PRISIGDd...........tGST....KLNM.....AWRLLWRDDRYTGGGVPEVEAQY-r..
A0A0H3KJI5_BURM1/41-139 ..........ipdpag-------LVIRSGQSVPCDGIWEPVAIepsrisg..................tipvdakrFRNNG..CFNYFVADVIAp....gfADVDVDT.............FDV...tLRCT.....YWRLLWEDTRYTNGVVPDESQYI-l..
A0A1N6KVC4_9BURK/214-294 ................PKNESREGEVHSGQEIPVEGIWEPWFP.................................AGKVG..CPNYFLKGSAA.......HTYLLEG.............TND....EHAV.....RWRLLWEDKRYQDGSIPVEEETYF...
A4J9U7_BURVG/212-307 ..........evpepv------GPVIKSGHKVPCDGIWEPVTVrrskllg..................vvpvgnrsLHNNG..CFNYFIRDIRA.......PNLRDDE.............TRT....PVKT.....HWRLLWEDKRYADGIVPDESEYFL...
A0A4S3K5B4_9GAMM/190-290 ...............p-LPDPRSPKLKTGKKIPVTGIWIATTT.................................LN--A..CPNFLVAGQPApelrrpcERLDYEAtpaaggepardawS-DyefaDEAT.....VWQLVWTDTRYRGAESEDES----aml
A0A0N1B6X7_9PROT/178-280 ............ptps-----EEVLIPTGDEAPCSGIYEPVKAawskgvltlf.............rrpvpdpdgqYELDG..CMNYLHGGSPA.......PTIGFED.............DDEr.geGRKT.....VWRLLWADDRYTDGVVPEEEQTY-h..
A4JC60_BURVG/215-295 ................PKNESAAGEIHSGEEIPVEGIWEPWFP.................................AGKVG..CPSYFLKGSIA.......HTYLLEG.............TND....EHAV.....AWRLLWEDKRYRDGSIPAEEATYF...
A0A0H3KB63_BURM1/181-276 .............pvp---QAIGPVIKSGNKVPCDGIWEPVVVerekllg..................ivpighrrLRNNG..CFNYFIRDIRA.......PKLRDND.............LGL....PVKT.....HWRLLWEDKRYTDGVIPDESEYFL...
A0A2R4CB54_9BURK/193-292 ...........pdpat------STLVRTGRHVPCSGIWEPVDApapslwrwl...............arsprpappFKVQG..TMSYLHGGSPA.......PCATIET.............AGD....TMDIe...tTWRLLWKDERYRDGTVPEEESGY-r..
Q5GX25_XANOR/11-110 ...........pnpve------NTLVATGTRIPCSGIWEPVDApkpkkfslf...............skpdvpsgfLPYIA..AMNYLHGGSAA.......PKASQEI.............EDDv..lNIDV.....VWRLIWRDDRYEDGTIPDEEAGY-v..
B2JM82_PARP8/203-285 ................PRNEDNTGEVWSGRQIPVTGIWEPWAI.................................NPKIGvrCPNYYLAGDTA.......SQYQFEG.............TDT....LEDV.....RWRLIWKDSRYASGQTPYEEDEYF...
A0A7Z2GPJ0_9BURK/192-291 ..............em--PEPRGLMVRSGEEVPCDGIWEPMLIesarlth..................alplnvevMRNGG..CFNYFVAQTLA.......PNLSQLS.............-DD....QWDVvpvptHWRLLWEDTRYKDGTIPDESSYFL...
A0A0H3KB55_BURM1/38-133 ..............ev--PEAVGPVIKSGDKVPCDGIWEPVAIeqskllg..................vvpvgnrsLRNNG..CFNYFVQDIHA.......PNVRDDD.............TGA....IVKT.....HWRLLWEDKRYADGIIPDESQYFL...
A0A4Q4WAH1_9PEZI/6-36 .........eerglpt---------------------------.................................-----..-----------.......-------.............---....----.....TWRLLWRDTRYEDGTIPNEERDY-v..
I2B6Z8_SHIBC/189-298 ................PVPERRDIIIKTDDPVPCDGIWEPVNIlynhkfl..................vikdgisgFKNLG..AYNYFIRGMKApr..qiyYDVLMESdke.......mliTDDp.irYRDV.....HWRLVWEDTRYCDGITPDESEYFL...
#=GC seq_cons ......................shhlcoGcplPCsGIWEPVts...ph........................s...httsG..shNYhltGshA.......sshthEs.............scc.....hsl.....tWRLLWcDcRYpDGslP-EEptY....
//
