#=GF ID   Kbp-5
#=GF AC   PF20883.1
#=GF DE   KNL (Kinetochore null) Binding Protein 5
#=GF AU   Chuguransky S;0000-0002-0520-0736
#=GF SE   [1]
#=GF GA   31.10 31.10;
#=GF TC   36.40 159.50;
#=GF NC   26.90 26.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF CL   CL0729
#=GF RN   [1]
#=GF RM   22711988
#=GF RT   Sos7, an essential component of the conserved
#=GF RT   Schizosaccharomyces pombe Ndc80-MIND-Spc7 complex, identifies a
#=GF RT   new family of fungal kinetochore proteins.
#=GF RA   Jakopec V, Topolski B, Fleig U;
#=GF RL   Mol Cell Biol. 2012;32:3308-3320.
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family represents KNL (Kinetochore null) Binding Protein 5
#=GF CC   (Kbp-5) from C. elegans which interacts with KNL-1 and it is
#=GF CC   thought to be homologous to human Zwint and yeast Kre28 [1,2].
#=GF CC   Proteins in this family are part of the kinetochore network
#=GF CC   involved in chromosome segregation. Unlike its homologue Kre28,
#=GF CC   Kbp-5 has not essential mitotic function. 
#=GF SQ   9
#=GS A0A8R1IRE1_CAEJA/1-128  AC A0A8R1IRE1.1
#=GS A0A8R1DWR2_CAEJA/1-128  AC A0A8R1DWR2.1
#=GS G0NVF6_CAEBE/1-123      AC G0NVF6.1
#=GS A0A261BQW3_9PELO/1-126  AC A0A261BQW3.1
#=GS A8XFN2_CAEBR/1-125      AC A8XFN2.1
#=GS G0NH86_CAEBE/1-123      AC G0NH86.1
#=GS A0A2G5VLF2_9PELO/1-125  AC A0A2G5VLF2.1
#=GS O44956_CAEEL/1-124      AC O44956.1
#=GS E3LMQ4_CAERE/1-126      AC E3LMQ4.1
A0A8R1IRE1_CAEJA/1-128             MDPELNEELLKLYAQSITSEALNDVAKFLENHS.AQDRALIkERLLQKVLEEEQQVENKRKMVEALEKQNEELKKvaDENVERLQALQNLRERHNELQINSlQEN.SSV.QM.SQKQVDDLCRMKHEIAALS
A0A8R1DWR2_CAEJA/1-128             MNPELNEELLKLYAQSITCEALNDVAKFLENHS.AQDRALIkERLLQKVLEEEQQVENKRKMVEALEKQNEELKKvaDENVERLQALQNLRERHNELQKNSlQEN.SSV.QM.SQKQVDDLCRMKHEIAALS
G0NVF6_CAEBE/1-123                 MDPKENEAILDLYTQEISSRALKDAEKYLETS-.-GRGNQK.ELLLAKVLAEEQKVENNRKMLENLKAENNELKI..DLTKCDLKSLETMRAERDELQRKR.EAE.KDD.VSvSQKSIEMIQQLTRQIEKIR
A0A261BQW3_9PELO/1-126             MNPEENQKALEQYTQEISTEALKDAKHFLENSLpAGQGVQK.DILLAEVLSEEQQIEKNRKTIENSIKEQDDLNT..NLPEKELKTLEQLQFERNELQKKR.QEE.NIViAE.SYKSIDDIIRMKRETDEMR
A8XFN2_CAEBR/1-125                 MNPERNQDILELYSQEIFVKAIKDGEQFLENNL.PIDGDQK.DRLLTKVLEGEKKFEDNRKKMEGLKKEQAELKA..KLVDSDLEMLEKLRAERDELQRKH.QADnNET.IT.SQKSIDEILRMKQETAKMR
G0NH86_CAEBE/1-123                 MDPKENEAILDLYTQEISSRALKDAEKYLETS-.-GRGNQK.ELLLAKVLAEEQKVENNRKILENLKAENNELKI..DLTKCDLKSLETMRAERDELQRKR.EAE.KDE.VSvSQKSIEMIQQLTRQIEKIR
A0A2G5VLF2_9PELO/1-125             MNPERNQDILELYSQEIFVKAIKDGEQFLENNL.PIDGDQK.DRLLTKVLEEEKKFEDNRKKMEDLKKEQAELKA..KLVDSDLEMLEKLKAERDELQRKH.QADnNET.IT.SQKSIDEILLMKQETAKMR
O44956_CAEEL/1-124                 MNPNHNEGLLELYTQAISLEALKDAEQFLENSL.LGKDAQV.ERLLAQVLIEEQQIETNRKKIAQLRIEKEELEF..DCANSDLKSLEQMQAERDELQRKC.QPG.QHT.KS.NHKSSEQLLRMKKETDALR
E3LMQ4_CAERE/1-126                 MNPEENQKALEQYTQEISTEALKDAKHFLENSLpAGQGVQK.DILLAEVLSEEQQIEKNRKTIESSIKEHDDLST..NLPEEELKTLEQLQFERDELQKKR.QEE.NTViAE.SYKSIEDIIRMKRETDEMR
#=GC seq_cons                      MNPEcNpclL-LYoQEIoscALKDuc+FLENs..stcGsQK.-hLLsKVLpEEQplEsNRKhlEsLcKEpsELKt..cLscp-LcsLEpL+tERDELQ+K+.Qt-.sps.hp.SQKSI--IhRMK+EhschR
//