#=GF ID   LED_rpt
#=GF AC   PF20854.1
#=GF DE   LED repeat
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF AU   Chuguransky S;0000-0002-0520-0736
#=GF SE   Manual
#=GF GA   59.00 59.00;
#=GF TC   59.10 60.80;
#=GF NC   58.90 57.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP   Repeat
#=GF RN   [1]
#=GF RM   3474619
#=GF RT   Cloning of a brain protein identified by autoantibodies from a
#=GF RT   patient with paraneoplastic cerebellar degeneration.
#=GF RA   Dropcho EJ, Chen YT, Posner JB, Old LJ;
#=GF RL   Proc Natl Acad Sci U S A. 1987;84:4552-4556.
#=GF DR   SO; 0001068; polypeptide_repeat;
#=GF CC   This entry represents a six residue tandem repeat found in
#=GF CC   Cerebellar degeneration-related antigen 1 (CDR1) from human [1].
#=GF CC   It is rich in Glu and Asp and usually flanked on the N-terminal
#=GF CC   by hydrophobic residues (Leu/Phe) and on the C-terminal by an
#=GF CC   aliphatic residue followed by and Asp residue [1].
#=GF SQ   67
#=GS A0A8B8WGL7_BALMU/20-194   AC A0A8B8WGL7.1
#=GS A0A6P6BR58_PTEVA/53-147   AC A0A6P6BR58.1
#=GS CDR1_HUMAN/1-176          AC P51861.2
#=GS A0A2I3N2N4_PAPAN/22-188   AC A0A2I3N2N4.2
#=GS A0A2K6BX89_MACNE/51-218   AC A0A2K6BX89.1
#=GS A0A2K6MJ11_RHIBE/1-155    AC A0A2K6MJ11.1
#=GS G3S4M4_GORGO/1-170        AC G3S4M4.2
#=GS A0A3Q7NBB3_CALUR/1-155    AC A0A3Q7NBB3.1
#=GS A0A8U0RIS9_MUSPF/68-164   AC A0A8U0RIS9.1
#=GS A0A6P5AW45_BOSIN/1-126    AC A0A6P5AW45.1
#=GS A0A6P3HT25_BISBI/229-359  AC A0A6P3HT25.1
#=GS A0A5N3XH38_MUNRE/1-120    AC A0A5N3XH38.1
#=GS A0A6P6BR56_PTEVA/39-221   AC A0A6P6BR56.1
#=GS A0A2K5TLK3_MACFA/27-200   AC A0A2K5TLK3.2
#=GS A0A2Y9T0H9_PHYMC/269-405  AC A0A2Y9T0H9.1
#=GS A0A5N4C2S9_CAMDR/46-212   AC A0A5N4C2S9.1
#=GS A0A2K5K311_COLAP/33-115   AC A0A2K5K311.1
#=GS A0A3Q7UBK3_VULVU/17-187   AC A0A3Q7UBK3.1
#=GS H2PWZ4_PONAB/1-176        AC H2PWZ4.1
#=GS A0A8C5XY26_MICMU/71-134   AC A0A8C5XY26.1
#=GS A0A4U1EDQ2_MONMO/92-241   AC A0A4U1EDQ2.1
#=GS A0A7F8K9R2_DELLE/128-242  AC A0A7F8K9R2.1
#=GS A0A2R8ZND8_PANPA/22-188   AC A0A2R8ZND8.1
#=GS A0A2Y9RCQ0_TRIMA/1-117    AC A0A2Y9RCQ0.1
#=GS A0A5F4WM72_CALJA/29-96    AC A0A5F4WM72.2
#=GS A0A2Y9KTE0_ENHLU/90-187   AC A0A2Y9KTE0.1
#=GS A0A8U0RIS9_MUSPF/121-230  AC A0A8U0RIS9.1
#=GS A0A6J3G247_SAPAP/125-194  AC A0A6J3G247.1
#=GS A0A6J1YZE0_ACIJB/1-143    AC A0A6J1YZE0.1
#=GS A0A452CJV3_BALAS/20-194   AC A0A452CJV3.1
#=GS S9XV24_CAMFR/43-212       AC S9XV24.1
#=GS A0A3Q0CDM5_MESAU/1-106    AC A0A3Q0CDM5.1
#=GS A0A8B7QD24_HIPAR/1-79     AC A0A8B7QD24.1
#=GS A0A2K6NDI8_RHIRO/1-173    AC A0A2K6NDI8.1
#=GS L5JUP4_PTEAL/1-60         AC L5JUP4.1
#=GS A0A5F4WM72_CALJA/84-138   AC A0A5F4WM72.2
#=GS A0A643BMA8_BALPH/20-194   AC A0A643BMA8.1
#=GS A0A8C6MRH8_MUSSI/68-196   AC A0A8C6MRH8.1
#=GS A0A8B7QE68_HIPAR/1-74     AC A0A8B7QE68.1
#=GS A0A7F8K9R2_DELLE/1-130    AC A0A7F8K9R2.1
#=GS L5LQN4_MYODS/6-85         AC L5LQN4.1
#=GS A0A5F7ZHT8_MACMU/33-206   AC A0A5F7ZHT8.1
#=GS A0A2Y9T0H9_PHYMC/137-270  AC A0A2Y9T0H9.1
#=GS A0A2K5Y2G5_MANLE/51-139   AC A0A2K5Y2G5.1
#=GS A0A7F8RVZ2_LEPWE/1-161    AC A0A7F8RVZ2.1
#=GS A0A2K5KRJ0_CERAT/1-180    AC A0A2K5KRJ0.1
#=GS A0A671DHT6_RHIFE/73-202   AC A0A671DHT6.1
#=GS A0A7F8K9R2_DELLE/45-154   AC A0A7F8K9R2.1
#=GS A0A8B7QD24_HIPAR/96-266   AC A0A8B7QD24.1
#=GS A0A1S3FZY1_DIPOR/2-112    AC A0A1S3FZY1.1
#=GS A0A8I5Y912_RAT/124-264    AC A0A8I5Y912.1
#=GS A0A6J2MKU9_9CHIR/8-171    AC A0A6J2MKU9.2
#=GS A0A6J3G247_SAPAP/61-151   AC A0A6J3G247.1
#=GS A0A6P4YNS0_BRABE/10-145   AC A0A6P4YNS0.1
#=GS A0A3Q0E4N2_CARSF/89-162   AC A0A3Q0E4N2.1
#=GS A0A3Q1MC30_BOVIN/2-147    AC A0A3Q1MC30.1
#=GS A0A811Z2D1_NYCPR/1-108    AC A0A811Z2D1.1
#=GS A0A2K5Y2G5_MANLE/95-182   AC A0A2K5Y2G5.1
#=GS A0A8B7AQD4_ORYAF/36-219   AC A0A8B7AQD4.1
#=GS A0A8I5Y912_RAT/1-97       AC A0A8I5Y912.1
#=GS A0A6J3QU37_TURTR/1-183    AC A0A6J3QU37.1
#=GS A0A6J3A3R8_VICPA/13-152   AC A0A6J3A3R8.1
#=GS A0A8M1G6Q2_URSMA/1-174    AC A0A8M1G6Q2.1
#=GS A0A2U3ZY09_ODORO/1-155    AC A0A2U3ZY09.1
#=GS A0A8D2EKD4_THEGE/1-182    AC A0A8D2EKD4.1
#=GS A0A6J0YEY4_ODOVR/6-184    AC A0A6J0YEY4.1
#=GS A0A8C5XY26_MICMU/1-91     AC A0A8C5XY26.1
A0A8B8WGL7_BALMU/20-194              ..............pl---LEDMDFLEDAPFLEDVNF......LEDTPLLEDVDFLED...TALLEDVDFLEDAALLEDMDFLEDAPLL....EDMDFLED......VDFLEDMGRLEDMNLMEDTV.LL.....EDKDLLE....DMDFLEDVDFLEAMD........LME.DMDF......LEDLDRLEDL....EV.IGRHGFPGRHGF......SGRHQFSGRPEL....S...GRPGLF.GRHRFAGRLG............
A0A6P6BR58_PTEVA/53-147              ...............r---------------------......---------------...----------------------------....--------......----------QDLDLMEDVD.FL.....EDVILLG....DMDFLEDEALLEDVG........GLE.DKNF......LEDMDSLEDL....EV.IGRHGFLVRHGF......SGRCGFSGRPEL....S...GRPELF.GRRRFAGRPG............
CDR1_HUMAN/1-176                     ................MAWLEDVDFLEDVPLLEDIPL......LEDVPLLEDVPLLED...TSRLEDINLMEDMALLEDVDLLEDTDFL....EDLDFSEA......MDLREDKDFLEDMDSLEDMA.LL.....EDVDLLE....DTDFLEDPDFLEAID........LRE.DKDF......LEDMDSLEDL....EA.IGRCGFSGRHGF......FGRRRFSGRPKL....S...GRLGLL.GRRGFSGRLG............
A0A2I3N2N4_PAPAN/22-188              ................---------LEDVPFLEDVPF......LEDVPLLEDVPFLED...VPFLEDINLMEDMALLEDMDLLEDTDFL....EDLDFSEA......MDLREDKDFLEDVDSLEDMA.LL.....EDVDLLE....DTDFPEDVDFLEAMD........LRE.DKDF......LEDMDSLEDL....EA.IGRRGFSGRHGF......FGRCRFSGRPEL....S...GRPGLL.GRRRFSGRLG............
A0A2K6BX89_MACNE/51-218              ...............l---------LEDVPFLEDVPF......LEDVPLLEDIPLLED...TGRLEDINLMEDMALLEDVDLLEDTDFL....EDLDFSEA......MDLREDKDFLEDVDSLEDMA.LL.....EDVDLLE....DTDFPEDVDFLEAMD........LRE.DKDF......LEDMDSLEDL....EA.IGRRGFSGRHGF......FGRCRFSGRPEL....S...GRPGLL.GRRGFSGRLG............
A0A2K6MJ11_RHIBE/1-155               ................MAWLEDMDFLEDVPLLEDVPL......LEDVPLL--------...----EDINLMEDMALLEDVDLLEDTDFL....EDLDFSEA......MDLREDKDFLEDVD------.--.....-NVDLLE....DTDFLEDLDFLEAMD........LRE.DKDF......LEDMDSLEDL....EA.IGRRGFSGRHGF......FGRHRFSGRPEL....S...GRPGLL.GRRGFSGRLG............
G3S4M4_GORGO/1-170                   ................MAWLEDMDFLEDVPLLE----......--DVPLLEDVPLLED...TSRLEDINLMEDMALLEDVDLLEDTDFL....EDLDFSEA......MDLREDKDFLEDVDSLEDMA.LL.....EDVDLLE....DTDFLEDLDFLEAID........LRE.DKDF......LEDMDSLEDL....EA.IGRCGFSGRHGF......FGRRRFSGRPKL....S...RRPGLL.GRRGFSGRLG............
A0A3Q7NBB3_CALUR/1-155               ..............mq---------------------......-EDEQIPEDAGMPED...TEMLEDAEMPEDAEMPEDAEMSEDEQML....EALEMLEA......LEMXEDKDFLEDVAXLEDVD.FL.....EDVDFS-....GRPLLEDKDLLEDVD........FLE.AMDL......MEDMDFLEDL....EV.TGRHGFPGRHGF......SGRRGFSGRPEL....S...GRPGLF.GRRRFAGRPG............
A0A8U0RIS9_MUSPF/68-164              ...........rhkfc---------------------......---------------...---------LEDVDXLEDXDLVEDMDXL....EDLDFSEA......MDLTEDIDFLEDVDGTEDLDfFL.....EDINXLE....DLDFLEDISXLEDLD........LVE.DIFF......LEDVDSLEDL....R-.------------......------------....-...------.----------ll..........
A0A6P5AW45_BOSIN/1-126               ...............m-------EMLEDVEMLEDVEM......LEDVEMLEDVXXLED...VKMLEDVEMLEDVEMLEDTEMLEDEQML....EALEMLED......LEVXEDEDFLEDTPXLEDKD.FL.....EGAPSLE....DRDFLDYMDFLQCAP........SLE.DEDF......LDDTPLLED-....--.------------......------------....-...------.----------............
A0A6P3HT25_BISBI/229-359             .........ifwktwi--------------------F......LEGAPSLEDEDFLEE...MDRLEDMNFMEDTVLLEDKYLLEDMDFL....EDIDFLEA......MDLMEDMDFLED------MA.FL.....E------....DMDFQEDPNC-----........-PE.DLDY......LEDVDLLEDL....EV.IGRHEFSGRHGF......AGRPGFSGRHRF....-...------.----------cle.........
A0A5N3XH38_MUNRE/1-120               ...............m---------------------......---------------...-------------------------DRL....EDMNLMED......IVLLEDKYLLEDIDFLEAMD.LM.....EDMDFLE....DMAFLEDIDFQEDPN........CPE.DLDY......LEDVDLLEDP....KV.IGRHEFSGRRGF......AGRPGFSGRHRFylyfS...GRSGFD.GRRR------yfwktw......
A0A6P6BR56_PTEVA/39-221              .............wrs---LEDMDFLEDVELQEDLNC......LEDLDYLEDIDLLEAlevTGRLEDMNFLEDVALIEDLDLVEDTDFTwifpEDMDXMED......MDLVEDVDFLEDMALLEDMN.LM.....EDTALLE....DKDLLEVMGFLEAXD........LMG.DMDF......LEDVDSLEDL....MV.IGRHGFSGRHGA......SGRRGFSRRPEL....S...GRPRLF.GRRRFAGRPG............
A0A2K5TLK3_MACFA/27-200              ...............l---LEDVPFLEDVPFLEDVPF......LEDVPLLEDIPLLED...TGRLEDINLMEDMALLEDVDLLEDTDFL....EDLDFSEA......MDLREDKDFLEDVDSLEDMA.LL.....EDVDLLE....DTDFPEDVDFLEAMD........LRE.DKDF......LEDMDSLEDL....EA.IGRRGFSGRHGF......FGRCRFSGRPEL....S...GRPGLL.GRRGFSGRLG............
A0A2Y9T0H9_PHYMC/269-405             ................MAFLEDMDFQEDPNCPEDLDY......LEDIDLLEDLKLLED...MNFLEDVNLXEDISLLEDLNLVEDMNFL....EDVALLED......LDLVEDIDFLEDVDXLEDWI.WW.....KTWIFLE....DLDLMEDVVFLEDVD........XEE.DLDF.....fLEDMDXLEDL....D-.------------......------------....-...------.----------fm..........
A0A5N4C2S9_CAMDR/46-212              ................---LEDVDFLENAAMVEDVDF......LEDAAMVEDVDFLED...TAMLEDMDFLEDAALVEDVDFLEDAALV....EG------......MDFLEDTALVEDVDFLEDTN.LM.....EDTTLLE....DKDLLEDMDFLEAMD........LME.DMDF......LEDLDRLEDL....EV.IGRHGFPGRHGF......SGRHGFSGRPEL....S...GRPGLF.GRHKFAGRPG............
A0A2K5K311_COLAP/33-115              ...............f---------------------......---------------...----------------------------....--------......--------------------.-L.....EDVPLLE....D-DFLEDLDFLEAMD........LRE.DKDF......LEDMDSLEDL....EA.IGRRGFSGRHGF......FGRHRFSGRPEL....S...GRPGLL.GRRGFSGRLG............
A0A3Q7UBK3_VULVU/17-187              ...........wgkls----EDVEMLEDEKMLEDEEM......PEDVEMQEDAEMQED...AEMLEDAEMLEDEQMLEALEMLEALEMX....EDKDFLED......VAXLEDVDFLEDADFLEDVA.RL.....EDMYLME....DTQLLEDVDFLEAM-........---.--DF......MEDMDFLEDL....EV.TGRHGFPGRHGF......SGRRDFSGRPEF....S...GRPGLF.GRRRFAGRPG............
H2PWZ4_PONAB/1-176                   ................MAWLEDMDFLEDVPLLEDIPL......LEDVPLLEDVPLLED...TSRLEDINLMEDMALLEDVDLLEDTDFP....EDLDFSEA......MDLREDKDFLEDVDSLEDMA.LL.....EDVDLLE....DMDFLEDLDFLEAID........LRE.DKDF......LEDVDSLEDL....EA.IGRCGFSGRHGF......FGRRRFSGRPKL....S...GRPGLL.GRRGFSGRLG............
A0A8C5XY26_MICMU/71-134              ................---------------------......---------------...----------------------------....--------......--------------------.--.....-------....-----------EAMD........LME.DVDF......LEDMDRLEDL....DI.IGRCRFSGRYGF......CGRYGFSGRPEL....S...GRPGLF.GRHGFSGRLG............
A0A4U1EDQ2_MONMO/92-241              .............rha---------------------......----SLLEDMDFLED...TALLEDVDFLEDAALLEDVDFLEDAPLL....EDMDF---......---LEDVDFLEDMGRLEDMN.LM.....EDTVLLE....DKDLLEDMDLLED-D........LME.DMDF......LEDLDRLEDL....EV.IGRHGFPGRHGF......SGRHGFSGRPEL....RgliGRLDLV.EDMDFSGRSG............
A0A7F8K9R2_DELLE/128-242             ..............rs---------------------......---------------...---LEDMDFLEDMAFLEDMDFQEDPNCP....EDLDYSED......IDLLEDWKLLEDMNFLEDVN.LX.....EDISLLE....DLNLVEDMNFLEDVA........LLE.DLDL......VEDIDFVWKT....WI.DWKTGFGGRHGF......FW----------....-...------.----------kiw.........
A0A2R8ZND8_PANPA/22-188              ................---------LEDVPLLEDTPL......LEDTPLLEDTPLLED...TSRLEDINLMEDMALLEDVDLLEDTDFL....EDLDFSEA......MDLTEDKDFLEDVDSLEDMA.LL.....EDVDLLE....DTDFLEDPDFLEAID........LRE.DKDF......LEDMDSLEDL....EA.IGRCGFSGRHGF......FGRRRFSGRPKL....S...GRPGLL.GRRGFSGRLG............
A0A2Y9RCQ0_TRIMA/1-117               ................MDLLEDVAXSEDMNFLEDMAL......MEDMDFLEDVVLLED...VGRLEDIDLLEDVALLEDVDFLEDX---....EDMDFPEA......TDLMEDLDFLEDINFLEDVD.SL.....EDLEVLE....DVDFLEDINFLEDVD........SLE.D---......----------....--.------------......------------....-...------.----------............
A0A5F4WM72_CALJA/29-96               ..............le--MLEDMDLLEDVPLLEDVPL......LEDVPLLEDVLLLED...TGRLEDINLMEDMAFLEDVDLLEDMDSL....EDLD----......--------------------.--.....-------....---------------........---.----......----------....--.------------......------------....-...------.----------............
A0A2Y9KTE0_ENHLU/90-187              ...............d---------------------......---------------...----------------------------....--------......--FPEDVNLLEDVGRLEDMN.LM.....EDTQLCW....KTRICWKTXILEAMD........---.---F......QEDTDFLEDL....EV.IGRHGFPGRHSF......SGRRGFSGRPEL....S...GRPGFFgGRRRFAGRP-g...........
A0A8U0RIS9_MUSPF/121-230             ................--FLEDINXLEDLDFLEDISX......LEDLDLVEDIFFLED...VDSLEDLRLLEDVDCLEELKTLEDIDFL....EDVDFPX-......EDVVEDLXLLEDMDYLEDVN.FL.....EDXDXLE....DLMLLED--------........---.----......----------....--.------------......------------....-...------.----------lgvag.......
A0A6J3G247_SAPAP/125-194             ................---------------------......---------------...----------------------------....--------......--------------------.--.....-------....-----EDLDFLEAMD........LRE.DKDF......VEDMDSLEEL....DT.FGRRQFSGRHGF......FGRRRFSGRPEL....S...GRPGLF.GRRGFSGRLG............
A0A6J1YZE0_ACIJB/1-143               ..............ls---------------------......-------------ED...VEMLEDVELLEDAEMLEDEQMLEALEML....EALEMQED......VDFLEDAAXLEDVDFLEXTN.LL.....EDVGRPE....DMNLMEDTALLEDVD........LLE.DIDF......LEDVDFLEDL....EV.IGRRGFPGRHGF......------SGRPEL....S...GRPGLF.GRRRFAGRP-ggswkt......
A0A452CJV3_BALAS/20-194              ..............pl---LEDMDFLEDAPFLEDVNF......LEDTPLLEDVDFLED...TALLEDVDFLEDAALLEDMDFLEDAPLL....EDMDFLED......VDFLEDMGRLEDMNLMEDTV.LL.....EDKDLLE....DMDFLEDVDFLEAMD........LME.DMDF......LEDLDRLEDL....EV.IGRHGFPGRHGF......SGRHQFSGRPEL....S...GRPGLF.GRHRFAGRLG............
S9XV24_CAMFR/43-212                  ...............v-ALLEDVDFLENAAMVEDVDF......LEDAAMVEDVDFLED...TAMLEDMDFLEDAALVEDVDFLEDAALV....EG------......MDFLEDTALVEDVDFLEDTN.LM.....EDTTLLE....DKDLLEDMDFLEAMD........LME.DMDF......LEDLDRLEDL....EV.IGRHGFPGRHGF......SGRHGFSGRPEL....S...GRPGLF.GRHKFAGRPG............
A0A3Q0CDM5_MESAU/1-106               .............mys---------------------......------------LED...TNFWEDADFQEDVDFREDVDFREDADFR....EDXDFRED......VDFREDVDFREDVDFREDVD.FR.....EDVDSWE....DVDFREDLDFREDLD........FRE.DVDF......REDVDSREDL....--.------------......------------....-...------.----------xfw.........
A0A8B7QD24_HIPAR/1-79                ................---------------------......---------------...----------------------------....--------......------------------MG.RL.....EDMNLME....DTALLEDMDFLEAMD........LME.----......--VMDFLEDL....EI.IGRHGFSGRRGF......SGRPELSGRPGL....S...GRCRFA.GRPG------gywkm.......
A0A2K6NDI8_RHIRO/1-173               ................MAWLEDMDFLEDVPLLEDVPL......LEDVPFLEDVPLLED...TGRLEDINLMEDMALLEDVDLLEDTDFL....EDLDFSEA......MDLREDKDFLEDVDSLEDMA.S-.....--MDLRE....DKDFLEDLDFLEAMD........LRE.DKDF......LEDMDSLEDL....EA.IGRRGFSGRHGF......FGRHRFSGRPEL....S...GRPGLL.GRRGFSGRLG............
L5JUP4_PTEAL/1-60                    ...............l---------LEDVDFLEAVAL......LEDVDFLEDVVLLED...MGRLEDMNLMEDTALLEDKDLLEDVDFL....EA------......--------------------.--.....-------....---------------........---.----......----------....--.------------......------------....-...------.----------mi..........
A0A5F4WM72_CALJA/84-138              ................---------------------......---------------...----------------------------....--------......--------------------.--.....-------....---------------........---.--DL......LEDMDSLEDL....DT.FGRRGFSGRHGF......FGRRRFSGRPEL....S...GRPGLF.GRRGFSGRLG............
A0A643BMA8_BALPH/20-194              ..............pl---LEDMDFLEDAPFLEDVNF......LEDTPLLEDVDFLED...TALLEDVDFLEDAALLEDMDFLEDAPLL....EDMDFLED......VDFLEDMGRLEDMNLMEDTV.LL.....EDKDLLE....DMDFLEDVDFLEAMD........LME.DMDF......LEDLDRLEDL....EV.IGRHGFPGRHGF......SGRHQFSGRPEL....S...GRPGLF.GRHRFAGRLG............
A0A8C6MRH8_MUSSI/68-196              ................---------------------......---------------...-----------DLDFREDFDFWEDFDFP....EDLDFWED......FDFPEDVDFREDMDLWEDMD.FW.....EDLDFQE....DLDFWEDLDFWEDVD........LWE.DMDF......REDFDFWEDL....DY.LEDGGFSGRHGF......WGRRRFPGRCGF....L...GRHGFS.GRCGFNGR--qr..........
A0A8B7QE68_HIPAR/1-74                ...............m---------------------......---------------...----------------------------....--------......--------------------.--.....---NLME....DTALLEDKDFLEAMD........VM-.----......-EDMDFLEDL....EI.IGRHGFPGRHGF......SGRRGFSGRPEL....S...GRPGLS.GRCRFAGRPG............
A0A7F8K9R2_DELLE/1-130               ................------MDFLEDAPFLEDVNF......LEDASLLEDMDFLED...TALLEDVDFLEDAALLEDVDFLEDAPLL....EDMDFLED......VDFLEDMGRLEDMNLMEDTV.LL.....EDKDLLE....DMDLLEDVDFLEAXD........LME.DMDF......LEDLDRLEDL....RS.------------......------------....-...------.----------l...........
L5LQN4_MYODS/6-85                    .......hqgidsqpv---------------------......---------------...----------------------------....---NQSED......MNFLEDVDFLEDVTLLEDVG.ML.....EAINLME....DTALLEDQGLLEAVD........FLE.AMDL......IEDVDSPEDL....EL.IGR---------......------------....-...------.----------............
A0A5F7ZHT8_MACMU/33-206              ................--FLEDVPLLEDVPFLEDVPF......LEDVPLLEDIPLLED...TGRLEDINLMEDMALLEDVDLLEDTDFL....EDLDFSEA......MDLREDKDFLEDVDSLEDMA.LL.....EDVDLLE....DTDFPEDVDFLEAMD........LRE.DKDF......LEDMDSLEDL....EA.IGRRGFSGRHGF......FGRCRFSGRPEL....S...GRPGLL.GRRGFSGRLG............
A0A2Y9T0H9_PHYMC/137-270             ...............v-VFLEDVDFLEDTPLLEDMDF......PEDAPFLEDVNFLED...APLLEDVDFLEDMALSEDVDFLEDAALL....EDVDFLED......APLLEDMDFLEDVDFLEDMG.RL.....EDMNLME....DTVLLEDKDLLEDVD........CLE.TWRS......LEDMDFLEDM....--.------------......------------....-...------.----------a...........
A0A2K5Y2G5_MANLE/51-139              ................--FLEDVPLLEDVPLLEDVPF......LEDVPLLEDVPLLED...TGRLEDINLMEDMALLEDVDLLEDTDFP....EDVDFLEA......MDLREDKDFLEDMDSLEDL-.--.....-------....---------------........---.----......----------....--.------------......------------....-...------.----------............
A0A7F8RVZ2_LEPWE/1-161               ..............mp----------------EDEQT......QEDEQIPEDAGMPED...SEMPEDAEMPEDAEMPEDAEMPEDEQML....EALEMLEA......LEMXEDKGFLEDVAXLEDVD.FL.....EDVDFS-....GRPLLEDKDLLEDVD........FLE.AMDL......MEDMDFLEDL....EV.IGRHGFPGRHGF......SGRRGFSGRPEL....S...GRPGLF.GRRRFAGRPG............
A0A2K5KRJ0_CERAT/1-180               ........mdfledvp--LLEDVPFLEDVPLLEDVPL......LEDVPFLEDVPLLED...TGRLEDINLMEDMALLEDVDLLEDTDFL....EDLDFSEA......MDLREDKDFLEDVDSLEDMA.LL.....EDVDLLE....DTDFPEDVDFLEAMD........LRE.DKDF......LEDMDSLEDL....EA.IGRRGFSGRHGF......FGRLDFQEDPNY....P...ED----.----------ldywevtgrlgg
A0A671DHT6_RHIFE/73-202              .............wkl---------------------......---------------...-------------DLVEDMDWLEDLDFP....GRCGLMED......LDLVEDIDFLEDMDFLENIF.LL.....EDVGSLE....DMNLMEDKDLREDMD........FLE.AMDM......MEDMDFLEDL....EV.TGRHGFPGRHGF......SGRREFSGRPEL....S...GRPGLS.GRRRFAGRPG............
A0A7F8K9R2_DELLE/45-154              ...............l---------LEDVDFLEDAPL......LEDMDFLEDVDFLED...MGRLEDMNLMEDTVLLEDKDLLEDMDLL....EDVDFLEA......XDLMEDMDFLEDLDRLEDLR.SL.....EDMDFLE....DMAFLEDMDFQE---........---.----......----------....--.------------......------------....-...------.----------dpncp.......
A0A8B7QD24_HIPAR/96-266              .............rhe--FLEDVAWLEDMDFLEDMAF......LEDVALLEEMDFLED...MGRLEDMNLMEDRALLEDKDL------L....EDMDFLEA......MDLMEDIDFLEDVDSLEDLG.SL.....EDMYFLE....DMAFLEDVDFQEDPN........CPE.DLDC......LEDVDFVWKT....WI.DRKTGFGGRHGL......AGRLGFFWKMQN....D...GRSGFV.GRRRFSGRC-s...........
A0A1S3FZY1_DIPOR/2-112               ........ddlvgrqi---------------------......-----FLEDGEFLED...MDFLEDVDFLEDMDFLEAVDXLEDVDYL....EDMDFLEA......MDLMEDKDFLEDMDHLEDLE.VS.....EDVDWLE....DLSFMEDVDFQEDPN........CPE.DLDC......LEDTD-----....--.------------......------------....-...------.----------f...........
A0A8I5Y912_RAT/124-264               ................---------------------......---------------...---------LEDMDFQEDMDFQEDVDFR....EDLDFRED......LDFQEDLDFQEDLDFWEDMD.FR....eEDLDFWE....DMDFREVLDFWEDLD........FREeDLDF......LEDLDFREDL....D-.FGKTWIFGKTWI......FWKIWIFWKTWI....L...GRHGFS.GSLGFSGRLGfsrrhgfqe...
A0A6J2MKU9_9CHIR/8-171               ................----------------EDVEM......LEDEQMLEALEMLED...SEVXEDVSFLKGMAXLEDVDFLEDVPLL....EDMALLED......VDVLEDEDFVEDVALLEDIN.LMedsfwEDKDLLE....EKDLLEDMVSLEVAD........LPE.VMDL......IEDMDSLEDL....EV.TGRHGFPGRHGF......LEDVDFQ-RPEL....S...GRPCQF.GRCXFAGRLG............
A0A6J3G247_SAPAP/61-151              ..............vd--FLEDIASLEDVDFLEDVPL......LEDVPLLEDVLLLED...VGRLEDIHLMEDMALLEDVDLLEDTDFL....EDLDFLEA......MDLREDKDFVEDMDSLEE--.--.....-------....---------------........---.----......----------....--.------------......------------....-...------.----------l...........
A0A6P4YNS0_BRABE/10-145              ...........tfgla-----DRVALGDLSALEDLSA......LEELSSLEDLSALED...LSALEDLSDLEELSSLEHLSALEDPSDL....EELSSLED......LSALEDPSALEDLSALEDLS.AL.....EDLSALE....DPSALEDPSSLEDLS........SLE.DPSA......LEDLSSLEDL....SA.------------......------------....-...------.----------l...........
A0A3Q0E4N2_CARSF/89-162              ..........slvgrh---------------------......----GFLEDVPLLED...ISKLEDMNLMEDMVLLEDVDLLEDWIYW....KTWRFLED......MDCPEDINCLEDMDFLEDLG.--.....-------....---------------........---.----......----------....--.------------......------------....-...------.----------v...........
A0A3Q1MC30_BOVIN/2-147               etledvdiepafgrls---------------------......---------------...-------------SCLEDMEMLEDVEML....EDVEMLED......VEMLEDVEMLEDVKMLEDVE.ML.....ED-DFLE....DTPSLEDKDFLEGAP........SLE.DRDF......LEDMDFLEGFpgrrTF.IGRQGFSGRRGF......PGRRTFIGRQGF....S...GRRGFP.GRRTFIGRQG............
A0A811Z2D1_NYCPR/1-108               ................---------------------......---------------...--------------------MLEDEKML....EDEEMPED......VEMQEDAEMLEDAEMLEDEQ.ML.....EALEMLEaleiHTALLEDMDFLEAMD........LME.----......--DMDFLEDL....EV.TGRHGFPGRHGF......SGRRGFFRKTRI....-...------.----------vrktwit.....
A0A2K5Y2G5_MANLE/95-182              ................---------------------......---------------...----------------------------....--------......----------------EDMA.LL.....EDVDLLE....DTDFPEDVDFLEAMD........LRE.DKDF......LEDMDSLEDL....EA.IGRRGFSGRHGF......FGRCRFSGRPEL....S...GRPGLL.GRRGFSGRLG............
A0A8B7AQD4_ORYAF/36-219              ...............m---LEAMDLLEDMAXLEDMAL......LEDMNFLEDTVLLED...VGRLEDMDLMEDVALLEDMDFLEDX---....EDINFPEA......TDLMEDLDFLEDVDSLEDLR.SL.....EDVDFLE....DMDFQEDPNCPEDLDcwkmdtwrLLE.DMNFledvalLEDLDLLEDL....EV.LGRPGFFRKMWIdwkiwiWWKTYFSGRHEL....T...GRPGFL.----------sed.........
A0A8I5Y912_RAT/1-97                  ............mdfq---------------------......---------------...----EDLDFLEDLDFLEDLDFLEDLDFL....EDVDFSED......LDFREDLDFQEDMDFSGTLG.FL.....EDVDFIE....DLDFLEDLDFLEVLD........FWE.DLDF......QEDLDFPEDM....--.------------......------------....-...------.----------............
A0A6J3QU37_TURTR/1-183               ................MEMLEDVEMLEDVEMLEDTEM......LEDEQMLEALEMLED...LEMXEDMDFLEDMVFLEDVDFLEDTPLL....EDMDFLEDapfledVNFLEDAPLLEDMDFLEDTA.LL.....EDVDFLE....DAALLEDVDFLEDAP........LLE.DMDF......LEDVDFLEDM....GSfVGRQGFAGRHGS......PGRRGFSGXPGF....D...GRHGFS.GRLGXAGRP-g...........
A0A6J3A3R8_VICPA/13-152              ...........teyls----EDMEVLEDVEMLEDMEM......LEDKKTLEALEMLED...LEVXEDMDFLEDVALLEDVDLLEDKDLL....EDMDFLEA......MDLMEDMDFLEDLDRLEDLR.SL.....EDMDFLE....DMDFQEDPNC-----........-PE.DLDY......LEDINLLEDQ....EV.TGRHKFSGRH--......------------....-...------.----------............
A0A8M1G6Q2_URSMA/1-174               ..........mledae--MLEDEQMQEDEQMLEDEQM......MEDAEMSEDAEMLED...SEMPEDAEMPEDEQMLEALEMLEALEMX....EDKDFLED......ASXLEDVDFLEDVDFLEDVN.LL.....EDVALLE....DKDLLEDVNFLEAI-........---.--DL......MEDMDFLEDL....EV.IGRHGFPGRHGF......SGRRGFSGRPEL....S...GRPGLF.GRRRFAGRXG............
A0A2U3ZY09_ODORO/1-155               ..............mq---------------------......-EDEQIPEDAGMPED...SEMPEDAEMPEDEQMPEDAEMPEDEQML....EALEMLEA......LEMXEDKDFLEDVAXLEDVD.FL.....EDVDFS-....GRPLLEDKDLLEDVD........FLE.AMDL......MEDMDFLEDL....EV.TGRHGFPGRHGF......SGRRGFSGRPEL....S...GRPGLF.GRRRFAGRPG............
A0A8D2EKD4_THEGE/1-182               ................MAWLEDMDFLEDVPLLEDVPFledvpfLEDVPLLEDVPLLED...TGRLEDINLMEDMALLEDMDLLEDTDFL....EDLDFSEA......MDLREDKDFLEDVDSLEDMA.LL.....EDVDLLE....DTDFPEDVDFLEAMD........LRE.DKDF......LEDMDSLEDL....EA.IGRRGFSGRHGF......FGRCRFSGRPEL....S...GRPGLL.GRRRFSGRLG............
A0A6J0YEY4_ODOVR/6-184               .etledvdiepafgrl------------SSCLEDTEM......LEDVEILEDVEILED...VEMLEDVKMLEDVEMLEDVEMLEDTEML....EDEQMLEA......LEMLEDLEVXEDEDFLEDTP.SL.....EDKDFLE....DVALLEDKDFLEGAP........SLE.DRDF......LEDVDFLEGA....PX.IGRQGFSGRHGF......PGRRTFIGRRGF....S...GRRGFP.GRRTFIGRLG............
A0A8C5XY26_MICMU/1-91                ................MAILEDVDFLEDVVLLEDIDF......LEDKALLEDVPLLED...IGMLEDINLMEDMALLEDVDLLEDTDFL....EDVDFPEA......MDLMEDVDFLEDMDRLEDL-.--.....-------....---------------........---.----......----------....--.------------......------------....-...------.----------............
#=GC seq_cons                        ............................................ED..hlEDh.hLED...hthLEDhphhEDhshLEDhDhLEDhshL....EDh-h.Es......hDhhEDh-hLEDhc.LEDhs.hL.....EDhshLE....DhshhEDhDFLEshD........hhE.DhDa......LEDhD.LEDL....-s.hGRpGFsGRHGF.......GRhtF.tR.th....s...GR.th..Gcht..................
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