#=GF ID LPD26
#=GF AC PF18842.5
#=GF DE Large polyvalent protein associated domain 26
#=GF AU Mistry J;0000-0003-2479-5322
#=GF AU El-Gebali S;0000-0003-1378-5495
#=GF AU Iyer LM;0000-0002-4844-2022
#=GF AU Aravind L;0000-0003-0771-253X
#=GF AU Burroughs AM;0000-0002-2229-8771
#=GF SE Iyer LM
#=GF GA 27.00 27.00;
#=GF TC 68.60 67.00;
#=GF NC 25.50 25.00;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP Domain
#=GF RN [1]
#=GF RM 28559295
#=GF RT Polyvalent Proteins, a Pervasive Theme in the Intergenomic
#=GF RT Biological Conflicts of Bacteriophages and Conjugative Elements.
#=GF RA Iyer LM, Burroughs AM, Anand S, de Souza RF, Aravind L;
#=GF RL J Bacteriol. 2017; [Epub ahead of print]
#=GF DR INTERPRO; IPR040936;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC This is a small alpha-helical domain with two acidic residues
#=GF CC conserved in a predicted loop between two of its helices [1].
#=GF CC The domain is mainly found in polyvalent proteins of conjugative
#=GF CC elements [1].
#=GF SQ 53
#=GS A0A1Y4TJP8_9FIRM/728-790 AC A0A1Y4TJP8.1
#=GS A0A143Y2M1_9FIRM/890-951 AC A0A143Y2M1.1
#=GS A0A3A9D0Q0_9BACT/10-66 AC A0A3A9D0Q0.1
#=GS A0A371IL78_9FIRM/890-951 AC A0A371IL78.1
#=GS A0A1I5VY04_9FIRM/554-616 AC A0A1I5VY04.1
#=GS C0EFU8_9FIRM/10-66 AC C0EFU8.1
#=GS F0Z1Z3_9CLOT/771-833 AC F0Z1Z3.1
#=GS C0EI13_9FIRM/11-67 AC C0EI13.1
#=GS R9JCC7_9FIRM/15-71 AC R9JCC7.1
#=GS R9IJC1_9FIRM/10-66 AC R9IJC1.1
#=GS A0A1Y3Y256_9FIRM/890-951 AC A0A1Y3Y256.1
#=GS B9YBX0_9FIRM/561-623 AC B9YBX0.1
#=GS A0A1Y4EV43_9FIRM/805-867 AC A0A1Y4EV43.1
#=GS A0A395YH93_9CLOT/11-67 AC A0A395YH93.1
#=GS A0A1Y4LDF5_9FIRM/906-967 AC A0A1Y4LDF5.1
#=GS A0A2K9P0E0_9FIRM/786-847 AC A0A2K9P0E0.1
#=GS A0A7X3SLI1_9FIRM/15-71 AC A0A7X3SLI1.1
#=GS A0A3A9BS64_9BACT/11-67 AC A0A3A9BS64.1
#=GS C4ZEQ4_AGARV/10-66 AC C4ZEQ4.1
#=GS V2YEN2_9FIRM/10-66 AC V2YEN2.1
#=GS A0A1Y4RL54_9FIRM/890-951 AC A0A1Y4RL54.1
#=GS R9LJM8_9FIRM/10-66 AC R9LJM8.1
#=GS E7GMB8_CLOSY/10-66 AC E7GMB8.1
#=GS A0A6B1UE33_9FIRM/890-951 AC A0A6B1UE33.1
#=GS A0A328UEK2_9FIRM/16-77 AC A0A328UEK2.1
#=GS A0A7W8HC77_9FIRM/890-951 AC A0A7W8HC77.1
#=GS C0D7C8_9FIRM/591-647 AC C0D7C8.1
#=GS A0A3A8YE65_9BACT/10-66 AC A0A3A8YE65.1
#=GS A0A417NA24_9FIRM/890-951 AC A0A417NA24.1
#=GS A0A0S2W770_9FIRM/890-951 AC A0A0S2W770.1
#=GS C0CYA6_9FIRM/906-967 AC C0CYA6.1
#=GS A0A1Y4NQA5_9FIRM/891-952 AC A0A1Y4NQA5.1
#=GS A0A3A9DAS6_9BACT/14-70 AC A0A3A9DAS6.1
#=GS A0A3A9CPF0_9BACT/10-66 AC A0A3A9CPF0.1
#=GS N1Z9H3_9CLOT/10-66 AC N1Z9H3.1
#=GS A0A2K2TUK6_9CLOT/784-845 AC A0A2K2TUK6.1
#=GS S2LAH6_9FIRM/793-855 AC S2LAH6.1
#=GS R9M5G5_9FIRM/210-271 AC R9M5G5.1
#=GS R9N325_9FIRM/15-71 AC R9N325.1
#=GS A0A367GI52_9FIRM/907-968 AC A0A367GI52.1
#=GS A0A417KKT4_9CLOT/554-616 AC A0A417KKT4.1
#=GS R9LCU2_9FIRM/90-152 AC R9LCU2.1
#=GS A0A3E3HWM3_9FIRM/795-857 AC A0A3E3HWM3.1
#=GS A0A143X366_9FIRM/891-952 AC A0A143X366.1
#=GS A0A328UE68_9FIRM/1028-1089 AC A0A328UE68.1
#=GS A0A396Q145_9CLOT/177-238 AC A0A396Q145.1
#=GS F7JRC4_9FIRM/103-155 AC F7JRC4.1
#=GS U5F4H4_9FIRM/907-968 AC U5F4H4.1
#=GS A0A416EMR8_9FIRM/784-845 AC A0A416EMR8.1
#=GS E7GU87_CLOSY/802-864 AC E7GU87.1
#=GS A0A7G9G4N4_9FIRM/907-968 AC A0A7G9G4N4.1
#=GS E7GQ73_CLOSY/890-951 AC E7GQ73.1
#=GS A0A174BBX2_9FIRM/796-858 AC A0A174BBX2.1
A0A1Y4TJP8_9FIRM/728-790 ......QPAPDSVFSKLPPEQQQEmtdsvKSMLQTLIDADVKSTGEVTQGTLEAIQTQGFVLsGDGTLQ.
A0A143Y2M1_9FIRM/890-951 ......QEQQTPVFDKLPPEQQQAlsdtvQDTLQMLVDADKRIYGDVTGKTLEAIAAQGYSY.KDGQLE.
A0A3A9D0Q0_9BACT/10-66 .....e-GEMRRAWGGKLPEEFTQ.....QDMLAFMADTDLLLGGTVSAETLSAIHAAGYDY.MGGAVI.
A0A371IL78_9FIRM/890-951 ......QEQQTPVFDKLPPEQQQAlsdtvQDTLQMLVDADKRIYGDVTGKTLEAIAAQGYSY.KDGQLE.
A0A1I5VY04_9FIRM/554-616 ......QPDPDSVFSKLSPEQQQEmtasvKAMLQTLIDADLKSTGEVSQGTKEAAQAQGFTIvGDGTLE.
C0EFU8_9FIRM/10-66 .....e-GEMRRAWGGKLPEEFDQ.....RDMLAFMAETDLQLHGAVSAETLSAIHAAGYDY.EGGAVI.
F0Z1Z3_9CLOT/771-833 ......QTNPDGVFSKLPPKQQQAmteevRATLQMLIDTDLKSTGEVSQGSKEAAQAQGFTIaGDGTLE.
C0EI13_9FIRM/11-67 ......DGSVQRLWNGKLVEDFTE.....ADTLRFMADTDIQLHGKVSADILAAIKKAGYRY.EGGEV-l
R9JCC7_9FIRM/15-71 .....a-GQMRRTWNGKLPEEFNE.....RDMLLFAADTDLALYGRVSDETLNAARKAGYSY.ENGALM.
R9IJC1_9FIRM/10-66 .....e-GEMRRAWGGKLPEEFTQ.....QDMLAFMADTDLLLGGTVSAETLSAIHAAGYDY.MGGAVI.
A0A1Y3Y256_9FIRM/890-951 ......QEQQTPVFDKLPPEQQQAlsdtvQDTLQMLVDADKRIYGDVTGKTLEAIAAQGYSY.KDGQLE.
B9YBX0_9FIRM/561-623 ......QPAPDSVFSKLPPEQQQEmtdsvKAMLQTLIDADVKSTGEVTQGTLDAIQTQGFVLsGDGTLQ.
A0A1Y4EV43_9FIRM/805-867 ......QPNQDSVFSKLPPEQQAAmteevRATLQALIDADLNATGQVSQGTKDAIQTQGFTLsDDGKLQ.
A0A395YH93_9CLOT/11-67 .....d-GSIQPLWHGKLAEDFTE.....ADTLRFMADTDIQLSGNVSADTLAAIRRAGYRY.EGGEV-l
A0A1Y4LDF5_9FIRM/906-967 ......QAQQTPVFDKLSPEQQQAlsdtvKDTLQLLVDADKRIYGDVTGKTLEAIAAQGYSY.KDGQLE.
A0A2K9P0E0_9FIRM/786-847 ......QAQQTPVFDKLSPEQQQAlsdtvKDTLQLLVDADKRIYGDVTGKTLEAIAAQGYSY.KDGQLE.
A0A7X3SLI1_9FIRM/15-71 .....t-GQMRRTWNGKLPEEFNE.....KDMLLFAIDTDLTLNGRVSADTLDAVRKAGYSY.ENGALM.
A0A3A9BS64_9BACT/11-67 .....d-GSIQPLWHGKLAEDFTG.....ADTLRFMADTDIQLNGNVSAETLAAIRRAGYRY.EGGEV-l
C4ZEQ4_AGARV/10-66 ......DGQPNPAFYGKLPEEFSK.....ADTMRFMVETDLKLSGCVSADTLAALRAEGYDY.KDGNLV.
V2YEN2_9FIRM/10-66 ......DGEMRRTWGGKLPEEFTR.....QDVLAFMADTDLLLSGNVSKETLAAIHAAGYDY.KGGAV-l
A0A1Y4RL54_9FIRM/890-951 ......QEQQTPVFDKLPPEQQQAlsdtvQDTLQMLVDADKRIYGDVTGKTLEAIAAQGYSY.KDGQLE.
R9LJM8_9FIRM/10-66 .....e-GEMRRAWGGKLPEEFTQ.....RDMLAFMAETDLQLQGTVSAETLSAIHAAGYDY.MGGAVI.
E7GMB8_CLOSY/10-66 ......DGQPHPAFYGKLPEEFSK.....ADTMRFMVETDLKLSGCVSADTLAALRAEGYDY.KDGNLV.
A0A6B1UE33_9FIRM/890-951 ......QEQQTPVFDKLPPEQQQAlsdtvQDTLQMLVDADKRIYGDVTGKTLEAIAAQGYSY.KDGQLE.
A0A328UEK2_9FIRM/16-77 .....p-TQETPVFDTLPPEQQQAlsdtvKDTLQMLIDADMAAHGEVTESTLEAVAAQGYSY.QDGQL-t
A0A7W8HC77_9FIRM/890-951 ......QEQQTPVFDKLPPEQQQAlsdtvQDTLQMLVDADKRIYGDVTGKTLEAIAAQGYSY.KDGQLE.
C0D7C8_9FIRM/591-647 .....p-RQDGFLVGGKATGPMTE.....QDALLLMANLDKRLFGMVTMETLEAAEKAGCRF.TDGALS.
A0A3A8YE65_9BACT/10-66 ......DGEMRRAWGGKLPEEFTQ.....RDTLAFMAETDLQLQGEVSAETLSAIHAAGYDY.KGGAVI.
A0A417NA24_9FIRM/890-951 ......QEQQTPVFDKLPPEQQQAlsdtvQDTLQMLVDADKRIYGDVTGKTLEAIAAQGYSY.KDGQLE.
A0A0S2W770_9FIRM/890-951 ......QEQQTPVFDKLPPEQQQAlsdtvQDTLQMLVDADKRIYGDVTGKTLEAIAAQGYSY.KDGQLE.
C0CYA6_9FIRM/906-967 ......QAQQTPVFDKLSPEQQQAlsdtvKDTLQLLVDADKRIYGDVTGKTLEAIAAQGYSY.KDGQLE.
A0A1Y4NQA5_9FIRM/891-952 ......QEQQTPVFDKLPPEQQQAlsdtvQDTLQMLVDADKRIYGDVTGKTLEAIAAQGYSY.KDGQLE.
A0A3A9DAS6_9BACT/14-70 .....n-GDTRPAFYGKLPEEFNE.....RDMLAFAADTDPLLFQKVSEETLAAIHAAGYDY.QGGAVI.
A0A3A9CPF0_9BACT/10-66 .....e-GEMRRAWGGKLPEEFDQ.....RDMLAFMAETDLLLGGNVSAETLSAIHAAGYDY.EGGAVI.
N1Z9H3_9CLOT/10-66 .....e-GEMRRAWGGKLLEEFDQ.....RDMLAFMAETDLQLHGAVSAETLSAIHAAGYDY.TGGAVI.
A0A2K2TUK6_9CLOT/784-845 ......QEQQPPVFDKLPPEQQQAlsdtvKDTLQMLVDADKRIYGDVTGKTLEAIAAQGYSY.KDGQLE.
S2LAH6_9FIRM/793-855 ......QTNPDGVFSKLPPKQQQAmteevRATLQMLIDTDLKSTGEVSQGSKEAAQAQGFTIaGDGTLE.
R9M5G5_9FIRM/210-271 .....g-KEAAVLRYFAAPEQRQAisaevQATLQMLVDTDLKLYGEVTGDTLEAIQTQGFLL.RDGALI.
R9N325_9FIRM/15-71 .....a-GQMRRTWNGKLPEEFNE.....RDMLLFAADTDLALYGRVSDETLNAARKAGYSY.ENGALM.
A0A367GI52_9FIRM/907-968 ......QAQQTPVFDKLSPEQQQAlsdtvKDTLQLLVDADKRIYGDVTGKTLEAIAAQGYSY.KGGQLE.
A0A417KKT4_9CLOT/554-616 ......QPDPDSVFSKLPPEQQQEmtasvKAMLQTLIDADLKSTGEVSQGTKEAAQVQGFTIaGDGTLE.
R9LCU2_9FIRM/90-152 ......QPDPDSVFSKLPPEQQQEmtasvKAMLQTLIDADLKSTGEVSQGTKEAAQAQGFTIaGDGTLE.
A0A3E3HWM3_9FIRM/795-857 ......QPDPDSVFSKLSPEQQQEmtdsvKAMLQTLIEADLKSTGEVSQGTKEAAQAQGFTIaGDGTLE.
A0A143X366_9FIRM/891-952 ......QEQQTPVFDKLPPEQQQAlsdtvQDTLQMLVDADKRIYGDVTGKTLEAIAAQGYSY.KDGQLE.
A0A328UE68_9FIRM/1028-1089 .....s-TQETPVFDKLPPEQQQAlsdtvKDTLQMLVDADKRVYGDVTGSTLEAIAAQGYSY.KDGQLE.
A0A396Q145_9CLOT/177-238 ......QEQQTPVFDKLPPEQQQAlsdtvQDTLQMLVDADKRIYGDVTGKTLEAIAAQGYSY.KDGQLE.
F7JRC4_9FIRM/103-155 rrrqka---------------QQAlsdtvQDTLQMLVDADKRIYGDVTGKTLEAIAAQGYSY.KDGQLE.
U5F4H4_9FIRM/907-968 ......QAQQTPVFDKLSPEQQQAlsdtvKDTLQLLVDADKRIYGDVTGKTLEAIAAQGYSY.KGGQLE.
A0A416EMR8_9FIRM/784-845 ......QEQQPPVFDKLPPEQQQAlsdtvKDTLQMLVDADKRIYGDVTGKTLEAIAAQGYSY.KDGQLE.
E7GU87_CLOSY/802-864 ......QPNPDGVFSKLPPEQQQAmtdevRAMLQMLIDTDLKITGEVSQGTKEAIQTQGFTLsKDGTLE.
A0A7G9G4N4_9FIRM/907-968 ......QAQQTPVFDKLSPEQQQAlsdtvKDTLQLLVDADKRIYGDVTGKTLEAIAAQGYSY.KGGQLE.
E7GQ73_CLOSY/890-951 ......QEQQTPVFDKLPPEQQQAlsdtvQDTLQMLVDADKRIYGDVTGKTLEAIAAQGYSY.KDGQLE.
A0A174BBX2_9FIRM/796-858 ......QPDPDSVFSKLPPEQQQEmtasvKAMLQTLIDADLKSTGEVSQGTKEAAQAQGFTIaGDGTLE.
#=GC seq_cons ......psp.ssVFsKLsPEQQQthospVpDTLQhLlDsDh+lhG-VoucTLEAItAQGYoY.cDGpLp.
//
