#=GF ID   LRIM1_dimer
#=GF AC   PF20733.1
#=GF DE   Dimerization domain in LRIM1
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   ECOD:105.2.1
#=GF GA   35.00 35.00;
#=GF TC   38.80 67.70;
#=GF NC   33.20 30.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP   Coiled-coil
#=GF RC   Paper describing PDB structure 3oja
#=GF RN   [1]
#=GF RM   20826443
#=GF RT   A heterodimeric complex of the LRR proteins LRIM1 and APL1C
#=GF RT   regulates complement-like immunity in Anopheles gambiae.
#=GF RA   Baxter RH, Steinert S, Chelliah Y, Volohonsky G, Levashina EA,
#=GF RA   Deisenhofer J;
#=GF RL   Proc Natl Acad Sci U S A. 2010;107:16817-16822.
#=GF DR   SO; 0001080; coiled_coil;
#=GF CC   This entry represents the C-terminal coiled-coil dimerisation
#=GF CC   region of the anopheles LRIM protein. This region
#=GF CC   heterodimerises with a region of the APL1C protein [1]. LRIM1
#=GF CC   and APL1C are members of a family of proteins secreted by
#=GF CC   mosquitoes that contain an N-terminal LRR domain followed by a
#=GF CC   cysteine-rich region and a variable C terminus [1].
#=GF SQ   8
#=GS A7URS4_ANOGA/366-549      AC A7URS4.1
#=GS Q7Q5N3_ANOGA/323-509      AC Q7Q5N3.4
#=GS A0A182YLF4_ANOST/319-504  AC A0A182YLF4.1
#=GS A0A084WLM5_ANOSI/93-262   AC A0A084WLM5.1
#=GS A0A084WEL2_ANOSI/295-478  AC A0A084WEL2.1
#=GS A0A675B3M8_ANODA/315-500  AC A0A675B3M8.1
#=GS A7URS6_ANOGA/536-720      AC A7URS6.1
#=GS A0A182Y285_ANOST/384-567  AC A0A182Y285.1
A7URS4_ANOGA/366-549                 .........KPYLDRLL-----QYIAMTSVVEKQRKNE.pCSATDA-----INSAQSLYHYITQQAVV.SLQGNEQLEAEVNELRAEVQQLTNEQIQQEQLLQGLHAEIDTNlrrfrlskdeLARPSENLNKVFTHLKERHAFKLRETQARRTEA----DAKQKETEHLEQENIALERQldNKNTM.QILLRQLTLLKRQQIKQ--LLAKLS...
Q7Q5N3_ANOGA/323-509                 .........APFADRLIALKRKEHALLSGQGSETERLE..CERENQARQREIDALKEQYRTVIDQVTL.RKQAKITLEQKKKALDEQVSNGRRAHAELDGTLQQAVGQIELQ..........HATEEQSPLQLLRAIVKRYEEMYVEQQSVQNNAIRDWDMYQHKETQLAEENARLKKL..NGEAD.LALASANATLQELVVREQNLASQL-g..
A0A182YLF4_ANOST/319-504             .........APYAERLIDLKRKEYALFSRVGSEKERAE..CEKENKDRLRKVDMIKKQYSTTIDEETR.RNQMKIQLTQTKTALERKLPALQNAYNELAGELETVAAELQIT..........-VTEDHNLLQLLRSIVQRYEDHYIEEQGKQSNAIRDWDMYQKKETELLEENARMKKL..NGEAD.TALQKANATLQDLNVREQNLIKILS...
A0A084WLM5_ANOSI/93-262              avnnnittf----------------------EEEDRKE..CERYKEEKQKQLKAINDHYISQVEGAVReKLQQKEQLTIKKTKLANELNQ--PVYKDLEKLLRSMAESSDIP..........----FKDSLQALQDIVDKYDAAYQDEKKKQNDALKKRVEYEHELTQLALEKDQLEKK.kSIELD.ILLKKANATLQQLRTKDENLAN---vgn
A0A084WEL2_ANOSI/295-478             .........APFADRLIALKRREQSLFKQGNEAEEQKQ..CEKENALRSQRLAAIVQKYNLQVKLADQ.QRREKATLNVTKYELEGKLKEKEEIIHALTELLEAEAKNLDLK..........---YKENTLEMIDEIVQYYEDRYNAEQNKQRQAIKDLESFQKMIEQQLEEKERLEKL..NLDAD.FALQKANATLTELKEKQAQLTKTLA...
A0A675B3M8_ANODA/315-500             .........APFADRLIEQKRTQNSLLTVPTDPMSKAA.nCSTVDDARQQMISNMGSAITSVANEVQR.LQKDKIQLTSERLTLEQTVTLQREQSTSVRQALLAAAQKLNLP..........--VSQEASFVVLQKIIDQYEHLSKQEELERNKATEDWNKYSTEIDHWKREKARLEPL..IEKYD.ADISKANATLVDLTRQKAVLAEQL-k..
A7URS6_ANOGA/536-720                 .........KPYLDRLL-----QYIALTSVVEKLQRAQgrCSATDT-----INSVQSLSHYITQQGDV.PLQGNEQLEAEVNELRAEVQQLTNEQIQQEQLLQGLHAEIDTNlrryrlpkdgLARSSDNLNKVFTHLKERHAFKLRETQARRTEA----NAKQKETEDLEQENIALEKQldNKKAK.QAELRQETSQKRQKVKQ--LEAKK-n..
A0A182Y285_ANOST/384-567             ........f-PYLDRLI-----QYIHLTSSAEKVQRAErqCSQTDA-----ITSVRGLFNYLAM-VGN.GVQLNPKLQAEINELQSEIQQLTNTKAQHEQLLQSLQTEIDDNlrryrvikdpMIPHSQNLHKVIAHLKSRQAFKLQESKDRRSEA----DRKRQEVEALVQENLTLKNQ.lTLKTDkQKQIKQETTDKRRQVMM--LEKKK-n..
#=GC seq_cons                        .........tPahDRLI.....pahhhosssEcpcRsE..Cpppcs.+.p.IsulpstYphlsppssp.phQtK.QLpsc+scLcsclpphpstptpl-pLLpuhssclDls...........hhppcNhhpllpcIlcRY-t+hpEpQs+pscAhcch-taQ+Eh-pLtpENtpLEKh..NtcsD.tsLtKANATLpcLpl+pt.LtppL....
//