#=GF ID   Lentivirus_VIF
#=GF AC   PF05851.15
#=GF DE   Lentivirus virion infectivity factor (VIF)
#=GF AU   Moxon SJ;0000-0003-4644-1816
#=GF SE   Pfam-B_9439 (release 8.0)
#=GF GA   25.00 25.00;
#=GF TC   418.90 418.60;
#=GF NC   22.10 21.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   10441553
#=GF RT   The feline immunodeficiency virus vif gene is required for
#=GF RT   productive infection of feline peripheral blood mononuclear
#=GF RT   cells and monocyte-derived macrophages. 
#=GF RA   Lockridge KM, Himathongkham S, Sawai ET, Chienand M, Sparger EE; 
#=GF RL   Virology 1999;261:25-30.
#=GF DR   INTERPRO; IPR008668;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family consists of several feline specific Lentivirus
#=GF CC   virion infectivity factor (VIF) proteins. VIF is essential for
#=GF CC   productive FIV infection of host target cells in vitro [1].
#=GF SQ   2
#=GS VIF_FIVPE/1-251      AC P16089.2
#=GS Q84810_9RETR/31-272  AC Q84810.1
VIF_FIVPE/1-251                 MSEEDWQVSRRLFAVLQGGVNSAMLYISRL-PPDEREKYKKDFKKRLFDTETGFIKRLRKAEGIKWSFHTRDYYIGYVREMVAGSTTSLSLRMYIYISNPLWHSQYRPGLkNFNKEWPFVNMWIKTGFMWDDIEKQNICIGGEVSPGWGPGMVGIAIKAFSCGERKIEATPVMIIRGEIDPKKWCGDCWNLMCLRNSPPKTLQRLAMLACGVPAKKWRGCCNQRFVSPYRTPADLEVIQSKPSWNLLWSGEL
Q84810_9RETR/31-272             LQDEYWHLNQ-LFVTYQIGIRTPSLWLTN-KDKLD----KFLLKKKLKHLEDKWVKQIRQADGIKWSLHTREWHTSLVKECVAGTG--NGLKLFVYIHSPLWR-EYRPNY.DWNPNWPYANCWISRKYMWDLDDSIKILSRNRPMEGWPPGWLGVVIKAFCCKECKYDWNPMEVIRQDIDPWDYCGDCWLFIVIRNTAPGSLQRLCMLQLGRPLLSWKCKSQCTFLDWRRTPLDALVIQDCLPWQWRVWMDL
#=GC seq_cons                   hp-E.Wplsp.LFsshQhGlpos.Lalop..s..-....Kh.hKK+LhchEstalKplRpA-GIKWShHTR-aahuhV+EhVAGos...uL+halYIpsPLW+.pYRPsh.saN.pWPasNhWIpptaMWD..-p.pIh.tscs..GWsPGhlGlsIKAFsCtEpKh-hsPh.lIRt-IDPhcaCGDCW.hhslRNosPtoLQRLsMLthGhPhhpW+spspppFls.hRTPhDh.VIQsp.sWphhh.h-L
//