#=GF ID LidA_Long_CC
#=GF AC PF18641.5
#=GF DE LidA long coiled-coil domain
#=GF AU El-Gebali S;0000-0003-1378-5495
#=GF SE ECOD:EUF08557
#=GF GA 26.50 26.50;
#=GF TC 36.70 33.40;
#=GF NC 26.10 25.80;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Coiled-coil
#=GF RN [1]
#=GF RM 22416225
#=GF RT Structural insights into a unique Legionella pneumophila
#=GF RT effector LidA recognizing both GDP and GTP bound Rab1 in their
#=GF RT active state.
#=GF RA Cheng W, Yin K, Lu D, Li B, Zhu D, Chen Y, Zhang H, Xu S, Chai
#=GF RA J, Gu L;
#=GF RL PLoS Pathog. 2012;8:e1002528.
#=GF RN [2]
#=GF RM 22011575
#=GF RT Protein LidA from Legionella is a Rab GTPase supereffector.
#=GF RA Schoebel S, Cichy AL, Goody RS, Itzen A;
#=GF RL Proc Natl Acad Sci U S A. 2011;108:17945-17950.
#=GF DR INTERPRO; IPR041463;
#=GF DR SO; 0001080; coiled_coil;
#=GF CC LidA, another Rab1-interacting bacterial effector protein [1],
#=GF CC is translocated by Legionella into the host cytosol at the
#=GF CC beginning of infection, and it localized to the
#=GF CC Legionella-containing vacuole (LCV) at the cytosolic surface
#=GF CC [2]. It has been shown that tight interaction with Rab1 allows
#=GF CC LidA to facilitate the Legionella targeting factor
#=GF CC (DrrA/SidM)-catalyzed release of Rab1 from GDP dissociation
#=GF CC inhibitors (GDI) [1]. The base of the protein is formed by two
#=GF CC antiparallel coiled-coil structures forming a long coiled-coil
#=GF CC domain [1, 2]. This region of LidA interacts with switch and
#=GF CC interswitch regions of Rab1 [1] the nucleotide binding pocket of
#=GF CC Rab8a [2], hence blocking access to the GDP/GTP-binding site to
#=GF CC a great extent [1].
#=GF SQ 40
#=GS A0A0W0Y5I5_9GAMM/425-600 AC A0A0W0Y5I5.1
#=GS A0A6F8T621_9GAMM/296-474 AC A0A6F8T621.1
#=GS A0A0W0YLX4_9GAMM/298-474 AC A0A0W0YLX4.1
#=GS A0A378LV40_9GAMM/216-388 AC A0A378LV40.1
#=GS A0A0W0TTA7_9GAMM/225-386 AC A0A0W0TTA7.1
#=GS A0A0W0V8E0_9GAMM/305-493 AC A0A0W0V8E0.1
#=GS A0A378I329_9GAMM/236-405 AC A0A378I329.1
#=GS A0A0W0XVS1_9GAMM/333-502 AC A0A0W0XVS1.1
#=GS A0A0W0ZY48_9GAMM/284-473 AC A0A0W0ZY48.1
#=GS A0A0W0VQG4_9GAMM/272-445 AC A0A0W0VQG4.1
#=GS A0A0W0Y172_9GAMM/169-361 AC A0A0W0Y172.1
#=GS A0A098G1V3_9GAMM/274-467 AC A0A098G1V3.1
#=GS A0A0W0VXQ3_9GAMM/346-535 AC A0A0W0VXQ3.1
#=GS A0A0W0Z6X1_LEGSP/344-523 AC A0A0W0Z6X1.1
#=GS A0A0W0R3X2_9GAMM/247-425 AC A0A0W0R3X2.1
#=GS A0A0W0ZWP0_9GAMM/266-454 AC A0A0W0ZWP0.1
#=GS A0A0W1ANU6_9GAMM/414-601 AC A0A0W1ANU6.1
#=GS W0BDG0_9GAMM/253-461 AC W0BDG0.1
#=GS A0A0W0ZV08_9GAMM/159-358 AC A0A0W0ZV08.1
#=GS A0A0W0VS70_9GAMM/165-348 AC A0A0W0VS70.1
#=GS A0A378LYX9_9GAMM/261-452 AC A0A378LYX9.1
#=GS A0A0W0R2P9_9GAMM/167-326 AC A0A0W0R2P9.1
#=GS A0A078L075_9GAMM/266-441 AC A0A078L075.1
#=GS G9EMP4_9GAMM/229-407 AC G9EMP4.1
#=GS A0A0W1ANU6_9GAMM/302-427 AC A0A0W1ANU6.1
#=GS Q5ZWZ3_LEGPH/387-580 AC Q5ZWZ3.1
#=GS A0A0W1AD35_9GAMM/139-299 AC A0A0W1AD35.1
#=GS A0A0W0ZAS5_LEGSP/153-330 AC A0A0W0ZAS5.1
#=GS A0A098GDE4_TATMI/265-428 AC A0A098GDE4.1
#=GS Q5ZWZ3_LEGPH/257-391 AC Q5ZWZ3.1
#=GS A0A3S0XRD7_9GAMM/288-494 AC A0A3S0XRD7.1
#=GS A0A0W1ANU6_9GAMM/232-313 AC A0A0W1ANU6.1
#=GS A0A0W0ZV08_9GAMM/363-470 AC A0A0W0ZV08.1
#=GS A0A0W1A949_9GAMM/239-417 AC A0A0W1A949.1
#=GS A0A433JKY0_9GAMM/250-446 AC A0A433JKY0.1
#=GS A0A222P0V9_9GAMM/329-508 AC A0A222P0V9.1
#=GS A0A0W0TH57_9GAMM/389-562 AC A0A0W0TH57.1
#=GS A0A6F8T0U8_9GAMM/155-328 AC A0A6F8T0U8.1
#=GS A0A0W0VUS2_9GAMM/220-393 AC A0A0W0VUS2.1
#=GS A0A0W1AD35_9GAMM/284-399 AC A0A0W1AD35.1
A0A0W0Y5I5_9GAMM/425-600 ........................................................pa--ERAKIEKGLADLKK...EIA...KDMDKIAEEAGTVSPEQ.............---.....................TKADIAKVNAKQVEVAATEDMLAVYK.....GE....KSAYKADGT.....P........T...SDF......N...DTAYVAP.................KGKSI....................................LKGDD.gSLYLVNKD.vTDV..N.........S...LSASQ.........KQQASSDFNRAK..GQMTSVEDVI.KNNRSGEHGLNN...QQLGAARQTQQTQLSQLSEMRMQIQK......................................................
A0A6F8T621_9GAMM/296-474 .......................................................svd----AKIQSQIDSISI...EMD...EILEQVDELIKL---NQ.............DEK.....................AATLMKKHTSMGLNRARHFDMLDVRK.....GN....KHYVTLDGKtelngQ........S...VSF......K...DAHFVLN.................KGQQI....................................IKDGD..KHYLLQPG..QDW..E.........S...VKDNQe.......aLKTAQVGFEQTK..HELMVVENLV.KLNKGLESTFTK...TQILEVHSKIKNIETEETLIKNQT--g.....................................................
A0A0W0YLX4_9GAMM/298-474 ........................................................da--RGLLLKAQIAKLSK...QMD...AQADKINDLLIA---GK.............DDE.....................ARALLEEQNALNLKAANLHDLLAVNE.....KR....KYYVNDQGE.....K........T...HNF......H...EAQFILA.................RGQRI....................................VKDGQ.gEIYLLQPN..QDW..E.........S...VKNDSa.......aKARALQDYKDLK..PQLMCVKKVV.AHNKGLETAMNQ...DNIAEKDKLIKENRAEGLLIANMISQ......................................................
A0A378LV40_9GAMM/216-388 ................................................nlsvdkleve--------------KD...KLQ...KEADAIADEMAQ--TGD.............EKK.....................LNQLVDKLNTIGFKIANVNDLIDT-K.....KD....KKFINENGE.....E........V...STY......K...KAAFVVP.................KDKTV....................................LKDGG..EYYLVPKG..TDL..D.........T...FKNMPq......eeKNRAKKDFQDKK..DDIQLVKKVV.ADTKDKEIDSNT...TNLAQSKAQHTMIKNQVNSLQSAR--an....................................................
A0A0W0TTA7_9GAMM/225-386 .........................................................l-EAMLHAEQALAHFEA...-LQ...LRGDAVNHELTA---GV.............---.....................LQNLIASQH--------LAEWHDVVA.....GN....RCAFDHNWE.....P........C...LEA......H...NAAYILR.................PELQV....................................VRDGN..TCYLLPAN..TRF..E.........D...LSLTA.........REEARQNFDARE..PEFRSIKRAV.AQQVETSKLDLQ...RQEKVCQMRVNRLSEDYQSLLNQRQ-s.....................................................
A0A0W0V8E0_9GAMM/305-493 .......................................................msp---AMMLEQRIDSLNH...TLE...EQAEEIARLLSVRGDRQtv........eqaETE.....................AMNLLQKHNGLHVQVAGLQDMLSVIK.....GE....KLLFDNDGR.....I........V...TSF......A...QAAFVMSqk.............qaKEYKI....................................LYKDG..KHYLLTPN..QDP..D.........Q...FDNLKr......eeKEQAEKSYNRLR..PDICNLKHLI.HHNKALEFHDHQ...KKKDSLSQRSEQMQSEILLISTQMNQ......................................................
A0A378I329_9GAMM/236-405 ........................................................dn--AQEAIKGQINELES...KLD...KQTDEISQLIAN---NE.............DKK.....................AMELLHEHNKLHLQVAGLKDMLAVVN.....EE....KKLFDKDGK.....E........T...DSF......K...EAAFILK.................PDQRV....................................VIQNN..KYYLVTGT..---..-.........Q...LTEDN.........KLQAEAKFNKLK..PEILAVKSLV.QENKKEEKAFHG...KRLEAATERNKTLQDEVSALNNKLNQ......................................................
A0A0W0XVS1_9GAMM/333-502 .........................................................n-AHIPQIEDKIKALSD...KLE...SQLDDIQQLIES---GK.............DEE.....................ARKILLEHNGLHLQIAGLKDMMGVLK.....GE....KVLYKEDGQ.....V........A...KSF......D...EAAFVLP.................MDKKV....................................VKRDD..KFYLIGAK..QDL..S.........T...MDEHD.........VLQAQKDFERAR..PEISNLKLLV.KHNHGLE----N...ERLQQVQDKSRSLHNDIMTLRNQLTQ......................................................
A0A0W0ZY48_9GAMM/284-473 .........................................................s-RRIRTIEHELNFHQAhlsQTA...TNYEELFRLALEQTRSR.............RQElks..............qhssPGQLDSELEGLQLREQGLVSALKVMR.....NK....KILLNDKLE.....Q........V...FDF......S...QARFIVKh...............eEAKCL....................................IQKND.gTYALIPKD..MDP..K.........K...LTPDQ.........WEQAKRNFDQEK..ERIQTPRFNF.MEKIQENLQKQI...QRKEQHLSLREILQVQRSEMHRARE-k.....................................................
A0A0W0VQG4_9GAMM/272-445 ....................................................tellrt------IDLKIQSLKD...---...-KADDIVKNIIE-NPEI.............LER.....................DPLLKTKMNTLFVEAGAWEDLKSVLK.....GN....KNLCNENGQ.....E........T...HSL......F...DAKYYVS.................KDQKL....................................HKDEKtgKFYLLQKD..QDF..D.........L...MTEDE.........KAKAHEKFVKHE..PELKRVSELV.THNKSLVLQEID...SQLKGHMQEKEKVLLEKKEIESEL--ql....................................................
A0A0W0Y172_9GAMM/169-361 ............llaaerveeeiaeidrkqlkltqkynslqallnehdayletiyqqs----------------...NPE...QSIQLINQRLETFNPVP.............QNK....................lVGKRIHQQ-AAEIHRQQLENILGVLK.....NE....KRMYDASGN.....K........V...IDF......R...QAAFFVP.................SHYQL....................................RMQDQ..HIYLFEHE..NE-..-.........-...-----.........------------..----------.------------...--------------------------ltnrpvrtphlidrahkiglhqhrdmlgtqqlllmkqaqdmsrlekrrnvaeek
A0A098G1V3_9GAMM/274-467 .........................................................k-AAHAHIQPHLDNIRN...KMD...EYLLHVEDLIKD---NQ.............DEE.....................ASILMKMHTALGLKIASHHDMVAVKN.....KD....KYYVGADGK.....E........V...DSF......K...EAHYVLNthkntndealkaiapelRRERI....................................HKDEN.kNYYLLKPG..QTW..D.........S...IKDNIa.......eKAEAHKRFKHRE..PELMIVKNLV.HHNKKLETEVHK...EQVEDVQGQIKTNEKEKQLANNQKN-i.....................................................
A0A0W0VXQ3_9GAMM/346-535 ........................................................kp--PTELLQQRIDGLIK...KLE...GQAELIGKLIEA---NN.............DEQ.....................ALRLLHEHNAMHVQVEGLRDMLAVMK.....GE....KVLYNDEGQ.....V........T...SDF......T...KAAFVLPkeeqgkn...lpkeeqgKKLSI....................................VHKNG..KYYLLRGHdpKDF..E.........S...LPEEV.........KTAAQKNFERAR..PDIANLKKLV.EHNKTLEGKEHK...SKKETLTQHTEDMQKDILLITNQILQ......................................................
A0A0W0Z6X1_LEGSP/344-523 ..........................................................KERRQLIESRLKQLEE...QLD...KQVTEIDSLIEQ---GR.............DEE.....................AMKRLHEHNGLHIQAAGLKDMLDVVKdpeekGK....KILFNSEGK.....Q........V...HSF......K...DADFIVA.................NDKKI....................................VKGED.gKFYLLGAS..QDI..N.........S...MEQED.........RLKAQKEFEKVR..PEISSLKNLV.QRNKTLEKTFHT...ERMQTITGQSDNLQKEILDLSNQLTQ......................................................
A0A0W0R3X2_9GAMM/247-425 ........................................................ki--NVRSIEDKILGLSK...QLD...ADAAEISRLLESENEED.............LLA.....................ARELLNQSNARNLQLGTLKDMLDVVN.....KK....SYLVKADGS.....T........A...SNF......A...EAEFILP.................KSKKI....................................IKDGD..QYYLVDAS..KDL..K.........D...IQADEn.......lKNQAAKAFQQAK..HDLMNVKSLV.SKNYHLEKTDHN...QTKTNLSERSEKMQQEIDLLAKQLT-a.....................................................
A0A0W0ZWP0_9GAMM/266-454 .........................................................d-RKIRMLEERLSFHQTqlqQPP...QTSEQLFQQLIDRVRVR.............LNEpeh...............ideSPYRVCEVEGLRLQERGLSQALQILR.....NE....KILLNPQLE.....R........V...YDF......S...QAQFIIDp...............nHLSRY....................................RRYGD..SYAYFSED.iSPE..R.........Q...LSEQD.........WLQAKLNYEESK..PNICTANFFC.NDQMKHELESLR...ERTQSCQSRAQELMNRIDKVQTTKLQ......................................................
A0A0W1ANU6_9GAMM/414-601 .......................ldlgatdlailiedhamkapkghhgglddnlvrvr----------------...---...-----------------.............---.....................----D-QQQTLNLELGHLFDMLAVLQ.....GL....KYFANKSGK.....R........V...PYG......E...ESVYIIDvsqqpvlv.ngqlyaidKSEEI....................................LEDTNenRFYLVPKG..TTL..E.........M...LKNEPe.......aQKRAERSFERLK.yDPSSTVKKLV.KDNNALEVSFME...GEISRHASDLANNLQ-----------vgkelsqsla............................................
W0BDG0_9GAMM/253-461 .......................................................lpl---HAKIDDQIAALTK...KMD...INARQIQKLVDLGSMHDgvvdathvrqglaEEEflgt............pllevARAKIEDSTADNLHVATLKDLKSVLN.....GD....KVFCNRSGS.....P........V...TSL......D...EAELVLPkdma........rmlreEKKQI....................................VEYEG..KYYLIKQG..QDV..K.........D...LSVDE.........KHAAYEACKSLR.pQERATVKHLI.QHNNGLEHRENE...HHKDIIFQKQQLQIQKIMEFANVV--ar....................................................
A0A0W0ZV08_9GAMM/159-358 keaiknyteaieklqqdiktleqreeklkteramltekhgtynkgleefnaaqfeaqs-------EKQITEQIE...ELQ...KEADLISDKMMQ-PGLK.............DED.....................IYRLGNELNTVGLKIASLEDILAAKR.....QNkdpeKVYADINGN.....V........K...DSAgkditkE...DAAFVLS.................KDQKI....................................EKDKD.gNYYLLQRE..QEL..K.........N...MAPEE.........IAQAKWDFQNKK..KDL-------.------------...--------------------------tvkvfsd...............................................
A0A0W0VS70_9GAMM/165-348 .........................................................e-DKIKAIEDEISKLEGtkeERD...EKAQAIFKLIDDGLKLG.............GQEgee..............mvaqAKKELEELNAKNLQIGTLKDMLAVTK.....GD....KIMYKSNGE.....T........T...TSF......Q...EADFVVP.................KDKQL....................................VKEGE..EFYLLNQG..---..E.........K...LSDEN.........RTTAKQDFDNAK..GEMSSVKNLV.SSNRSIEMGELD...QKVKNLSDRITQLQTEKSQEDKRTTQ......................................................
A0A378LYX9_9GAMM/261-452 .........................................................d-RRIRMLEDRIGFLQS...QLQdppKTPEQIYEKLIEDLTSKi...........gTTEsie...............eyiPSPTLTDEEDLRLQRHAFLQALQFIR.....KQ....KILLNSECQ.....P........V...EDI......E...QAHFIIDp...............nHQTRF....................................RRHGD..SYLVLTED..MDMnkE.........Q...LSEQE.........WEKAKQNYFQLR..PKICTVNSFY.KELMKEESEDLM...QRTQTCKRKAHNILDRINKVESQRS-e.....................................................
A0A0W0R2P9_9GAMM/167-326 ........................................................en--DTAAIQAKIDKLTSp.eALE...ADQKAIDDLIAE---GK.............DEE.....................AIARGRENQEKYAQVGALNDMLSVAK.....GE....KKMYGQDGQ.....P........V...TSF......K...DAAFIVP.................KDQNL....................................SKEGD..KYFLTNAG..GEK..K.........E...LQGAQ.........L-----------..AEMSSVRQLV.SSNRNAEINDIA...SRISNLNERKKEAEA-----------tlamgq................................................
A0A078L075_9GAMM/266-441 .........................................................q-ERVHATQNGLLDIQA...KMA...QLTTNILQLANQ---GQ.............DHE.....................ASQLMNHLDGLHIEAEGMQTMLDHAH.....SK....CHYFTEEGH.....S........T...DAY......H...KAAFIAP.................KDQHI....................................HRDKAtgQLLLLEKG..QKP..E.........D...MSAEE.........KAAAHAKFEQFK..PGFCNARGKV.KQYHDTEMRDYE...NTQKDLVERSEKMQQHILQLTDERNK......................................................
G9EMP4_9GAMM/229-407 ........................................................al--KPEDLDTLIEDLEN...HIH...AQTETITTLLESGDPAD.............EEE.....................ARQLLNKQNALNLQVASLKDLRSTRQ.....EEn..aKKFFNADGI.....Q........V...PSQ......K...DASFITN.................HDQKI....................................VKKDG..EYYLLKAD..QNI..D.........E...LSDAD.........KEDAKEGFKSAQ..HELMTVQKAV.QHTHKLEKSFFA...TQIIEVTAQKEQNTAERMTLENQIK-l.....................................................
A0A0W1ANU6_9GAMM/302-427 ...............................................evqqytrqlkl----------------...---...-----------------.............---.....................----------NELKLEVLRDLIDVLN.....GD....KFYVDAEGK.....P........VqppKDI......K...QAELVLA.................KGQKV....................................VVKDG..KGYLLKAG..QEF..D.........S...LTQDE.........KETANNSYQEAQ..HYMKQFKVLVaMHKREIELD---...--------------------------lgatdlailied..........................................
Q5ZWZ3_LEGPH/387-580 ........................................................at----IKMEALIHKLSL...EME...KQLETINNLIMSTDPKE.............NEE.....................ATKLLHKHNGLNLKLANLQDMLAVHR.....KE....KSFFNEKGE.....E........V...TSL......N...DAHYVIGkdqqlfnl.ggkfypihKEQKI....................................LEKDG..KFYLLKQG..EDW..E.........S...IKDSPe.......kQKKAEHDFHKLQ.yETPMTVKKLV.HHNKGLETTIHK...ERVEETKQQLEDNGKEKIEIANNISK......................................................
A0A0W1AD35_9GAMM/139-299 ..................dkavdqaqkeadvidkmpdskaqkeldlvinyleakqgvl----------------...---...-----------------.............-QEkmrtlpdrlpngkidpdydskLLALVDENNTNEVQLGVFRTLRDVKQ.....GK....ADMYDENGE.....K........T...LKF......S...EARYTVPk...............sKDSEL....................................VKDKE.gKVYLIPKD..PNK..A.........G...LSAED.........KLK---------..----------.------------...--------------------------dltsaqkveaekna........................................
A0A0W0ZAS5_LEGSP/153-330 .........................................................d-DAIQKIEDKIKELEA...NND...KDAQRIYGLVDE---GK.............ENE.....................ARDELQKLNAKNLQVGTLKDMLSVVK.....GE....KSLYTAEGE.....KidlndtnvV...DAF......K...ESGFIVP.................DGQKIvt...............................etnEETGE.kEFFLLGED..---..D.........E...LTDEN.........KESAKDAFDRKK..PELSSVKSLV.GDMKDKELTSIR...DEISKLQTSAN---------------esapvaks..............................................
A0A098GDE4_TATMI/265-428 .........................................................a-EKIADIKNMIATLNE...TIE...TKRAEIDRLVVA---NQ.............DAE.....................AMALLPELNSLNGQSAGMEDILSVLE.....GR....KLFYNAAGQ.....S........V...DSY......K...QADFILA.................KTQRL....................................YVDKQsgVTYLLTAS..SDL..DseglaklfnS...LSPKD.........KLTAQHHYERAK..PEISNLKALV.ASNKELELALHT...EKK-----------------------vr....................................................
Q5ZWZ3_LEGPH/257-391 ....................................................seelsl-----------SEINEkmeAFS...KDSEKLTQLMEK-HKGD.............EKT.....................VQSLQREHHDIKAKLANLQVLHDAHT.....GK....KSYVNEKGN.....P........V...SSL......K...DAHLAIN.................KDQEV....................................VEHEG..QFYLLQKG..-QW..D.........A...IKNNPa.......aLEKAQKDYSQSK..HDLATIK---.------------...--------------------------m.....................................................
A0A3S0XRD7_9GAMM/288-494 ...................................................vafndaq-----------AKFTE...EMH...ILQKEIDSLIEN-----.............DQD.....................PGEALQKLNALNLKFASMHDMKAISE.....GR....KYAL----E.....T........T...VDG......E...EAHFVIN.................KGDQLmtlndddelvavdpndesvkaldssklffqksgnqlVKDSD.gKMYLLRPG..QDL..E.........T...VKQNPqms...enaQQAAKESFERVK..QEVMTVKHVI.GLHKGMEKGAHD...KRVQATEELISANKAEKDLVDNQV--rl....................................................
A0A0W1ANU6_9GAMM/232-313 .................................................itdrlqdgv----------------...---...-----------------.............---.....................--------------------------.....SE....KLYVDANGK.....T........V...TDL......K...KAELVLS.................KGKKV....................................VVNDG..VGYILKDS..QEL..D.........D...LTEHE.........KKAAKNSYREVQ..QYTRQL----.------------...--------------------------kln...................................................
A0A0W0ZV08_9GAMM/363-470 .................................................vkdpegnai----------------...---...-----------------.............---.....................--------------------------.....--....---------.....-........-...-TY......D...KAAFVLS.................KGQKI....................................AKDKE.gNYYLLKEG..QDL..E.........T...MSDSD.........KKQAKNDFQHNK..NDLKIVKDVV.KDVEKEELNLNT...ARSTQAKAEKLMMQNQLTLMQSARA-k.....................................................
A0A0W1A949_9GAMM/239-417 ........................................................hh--SLSDIEKRILELKQ...QMD...AYVDEVNELLQT---GK.............DDE.....................ARILLHVLTGLNAQAAGYHDMIDVLR.....NK....KFFVNADGE.....A........V...TSV......K...DAELTLN.................ISQKI....................................VKDAD.gMLYLIKSS..DDW..D.........Q...IKADPh.......aKANARKGYEALKqdPQAMSVKKVV.QHNKVLELNLHS...IKVQETIALKQENQYLKMMITNEVTQ......................................................
A0A433JKY0_9GAMM/250-446 ......................................................lqwv-------NKNLADLVT...EQE...KLNRDIDDYILA-NKEDt..........pqFAE.....................LRDKLKEVQ---TKHANLHDFKEILS.....GT....KVLYDATGE.....V........T...QDL......T...QAQYALNkdtv.........lkgmKGMRL....................................AKDEH.gKLLLLAPG..QNL..E.........N...IVDPNek....kelQNKAHQLFLKAR..PELEFLNTLV.ERNKEVIQEQLKlqlAKKPEIEANVAALQMQIKQVEESKQQridqlkp...............................................
A0A222P0V9_9GAMM/329-508 .......................................................eft---TEHLELKINNLKE...TLE...KQAGKIGALIEE---GN.............EEK.....................ARQLLHKHNGLHVQYEGLRDMVAVLK.....GE....KTLWSKDGQ.....P........M...SSF......AqfgESAFILS.................KEQSI....................................VLHDG..KYYLLQKD..QSP..E.........NfpfLSEED.........KNRAHKDFERAR..PSISSLKTLV.HHNKTLEKGLQF...DKREAINTRSETMQQEILLISNQLTK......................................................
A0A0W0TH57_9GAMM/389-562 .........................................................e-DRIEVIESNAAKLDD...QIR...TDLKVIHELLQDGDVKK.............EKQ.....................AMAMIQEHQGLVAEMVTLKDMIAVLK.....GE....KRLVKKDGT.....E........T...MSY......K...EAAYILS.................PGQRV....................................VKDQH.gKSYLLTGH..QSL..D.........N...MTPHE.........KDKAHDKL----..RSLATIDKLL.HHNEKIELGKKR...QELKQVHKEIHDLRDQIQFMQQRKA-e.....................................................
A0A6F8T0U8_9GAMM/155-328 ........................................................tk--ALASIESELSRLEGseeERG...KEAAAIDKLIND---GQ.............IDE.....................AKKRVNVLNAKNIQIGTLKDMLSVVK.....GA....KVMYNKNGE.....E........V...KSF......D...KADFVVP.................KDKKI....................................VKEGD..EYFLLDKN..---..D.........E...LSATN.........RDEAKAAFEREE..PEMSSVKNLI.NTNRDSEMTELN...QELERISAKIKDLQSSS---------vqspstlsq.............................................
A0A0W0VUS2_9GAMM/220-393 .........................................................n-EAITKLQGELDKIAT...EIS...KKTNQITTLIAE---GK.............EKE.....................VKTALHELDGLHFREAFLTDLLDVSQ.....YK....KHLFDANGE.....L........T...NSL......T...KADFVLK.................RDKKI....................................VEHEG..QYYLINAD..QDI..H.........T...LSQDD.........KKEAAEEYQKSK..GADVSVKKMV.IENMEFEREHYD...KKSDSLEERGKQINEYKTLINNQLNQ......................................................
A0A0W1AD35_9GAMM/284-399 ..........................................lkdltsaqkveaekna----------------...---...-----------------.............---.....................--------------------------.....--....---------.....-........-...---......-...------T.................KEKEI....................................VKDPKtgKFYLIQKD..PDN..E.........G...LSAQQklqkltdnqKDEAERNFKKAE..PNMVNVKEFL.QNNKKNEMIMLH...QKQSMLITKLQST-------------mtlgqnpsqvnns.........................................
#=GC seq_cons .........................................................t......lptpltplpp...php...pphppIspLltp...tp.............ppc.....................stthlpchsuhplphusLcDhlsVhc.....uc....KhhhstsGp.....t........s...ssa......c...cAtFlls.................Ksp+l....................................l+css..caYLLpts..p-h..-.........s...lsspp.........+ppAcpsFpct+..scltslKplV.pcN+phEhp.hp...pchpphppphpp.ptph..htpth........................................................
//
