#=GF ID MSP1_C
#=GF AC PF07462.15
#=GF DE Merozoite surface protein 1 (MSP1) C-terminus
#=GF AU Moxon SJ;0000-0003-4644-1816
#=GF SE Pfam-B_21542 (release 10.0)
#=GF GA 29.80 29.80;
#=GF TC 131.50 131.50;
#=GF NC 24.50 24.20;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 12466500
#=GF RT Mosaic organization and heterogeneity in frequency of allelic
#=GF RT recombination of the Plasmodium vivax merozoite surface
#=GF RT protein-1 locus.
#=GF RA Putaporntip C, Jongwutiwes S, Sakihama N, Ferreira MU, Kho WG,
#=GF RA Kaneko A, Kanbara H, Hattori T, Tanabe K;
#=GF RL Proc Natl Acad Sci U S A 2002;99:16348-16353.
#=GF DR INTERPRO; IPR010901;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This family represents the C-terminal region of merozoite
#=GF CC surface protein 1 (MSP1) which are found in a number of
#=GF CC Plasmodium species. MSP-1 is a 200-kDa protein expressed on the
#=GF CC surface of the P. vivax merozoite. MSP-1 of Plasmodium species
#=GF CC is synthesised as a high-molecular-weight precursor and then
#=GF CC processed into several fragments. At the time of red cell
#=GF CC invasion by the merozoite, only the 19-kDa C-terminal fragment
#=GF CC (MSP-119), which contains two epidermal growth factor-like
#=GF CC domains, remains on the surface. Antibodies against MSP-119
#=GF CC inhibit merozoite entry into red cells, and immunisation with
#=GF CC MSP-119 protects monkeys from challenging infections. Hence,
#=GF CC MSP-119 is considered a promising vaccine candidate [1].
#=GF SQ 26
#=GS A0A1D3U8A2_9APIC/1016-1539 AC A0A1D3U8A2.1
#=GS K6UUJ2_PLACD/1012-1622 AC K6UUJ2.1
#=GS Q8I0U8_PLAF7/981-1536 AC Q8I0U8.1
#=GS A0A0L7KDM6_PLAFX/920-1442 AC A0A0L7KDM6.1
#=GS A0A024W7X9_PLAFA/822-1107 AC A0A024W7X9.1
#=GS W4IYZ7_PLAFP/916-1471 AC W4IYZ7.1
#=GS A0A1J1H3N0_PLARL/870-1400 AC A0A1J1H3N0.1
#=GS A0A679L3P5_PLAKH/1056-1359 AC A0A679L3P5.1
#=GS A0A679L3P5_PLAKH/1344-1647 AC A0A679L3P5.1
#=GS A0A653HE52_9APIC/238-451 AC A0A653HE52.1
#=GS W7JYM8_PLAFA/979-1534 AC W7JYM8.1
#=GS A5K724_PLAVS/1001-1576 AC A5K724.1
#=GS A0A509ALB2_PLABA/1078-1611 AC A0A509ALB2.1
#=GS A0A0L0CYS7_PLAFA/937-1491 AC A0A0L0CYS7.1
#=GS A0A1A8VP40_9APIC/1005-1545 AC A0A1A8VP40.1
#=GS A0A0L7LXP3_PLAF4/959-1513 AC A0A0L7LXP3.1
#=GS A0A1A8YQM1_9APIC/959-1497 AC A0A1A8YQM1.1
#=GS D4AFN2_PLAGO/970-1538 AC D4AFN2.1
#=GS MSP1_PLAYO/1058-1591 AC P13828.1
#=GS A0A024WQJ1_PLAFA/971-1525 AC A0A024WQJ1.1
#=GS A0A024VR46_PLAFA/953-1507 AC A0A024VR46.1
#=GS W7KFP9_PLAFO/981-1536 AC W7KFP9.1
#=GS A0A024X9M2_PLAFC/807-1362 AC A0A024X9M2.1
#=GS A0A0L1I842_PLAFA/946-1501 AC A0A0L1I842.1
#=GS A0A024W7K7_PLAFA/382-664 AC A0A024W7K7.1
#=GS A0A1D3JMS5_PLAMA/1105-1628 AC A0A1D3JMS5.1
A0A1D3U8A2_9APIC/1016-1539 .......................tqgnadddvsep------------EEKEIEV.EEFYKKYLEEVDKY.DDYFKAFLSSKKDAVNKMT.EKDWKELEEEVKTLKSRLDMSLDHYNKYKLKLGRLFKKNEKVLSSKEHIKELSILKAQLMRRQFMLNNP.RHVIHNFRVFFNKKRETEKKEVENTLKNTDALLKYYKARVKYYNGETFPLKTISEDTLEKENNYLNLEKFKLYSRLEGKLKQNINLEKENITYLSSGLYHVLSELKGIIHNKKYTGNPHAANMVEVNNALNLYKDLLPK...VET--V...AST..GA.ATQTQ.G-----GEG---ASAAAP..GTANG-----.---------.................................--.ETATVAHAEDYTEDDNNVIVLPLFGKKGTH.A-...FDQVTQGEAQD.K-DDNILNEITNEYEVVYVKPLAGVYKTLKKQLEAHVTAFHSNVTNMLESRLKKRNYFLEVLNSDLTQYKHATSDNYVIRDAYKLLDFEKKKKLLSSYKYIKDSVEKDVEIATDGIDYYEKMAALYKTYLESVNAQVDAIGKTG...........DDATKATNK.....................-KFLPFLASINAMYETLLEKVNTYNSQLKSSLNSCQLEK----irv........
K6UUJ2_PLACD/1012-1622 ................................lav-SGSSEEEPE---VKIEEL.KNIYEKHLSQIDNY.NDYFKKFLESQKENITKMD.DTQWKALGVEIEELKKKIQVSLDHYEKYKLKLDRFMKKKNKISNSKEQIKKLTSLKNKLQRRQNLLNNP.TSVLKNYTVFFNKKREAEKKEVENTLKNTEILLKYYKARAKYYIGEPFPLKTLSEESMQKEDNYLNLERFRVLSRMEGRLGNNIDLEKENISYLSSGLHHVFTELKEIINNKRYSGNDHAKNTAAVKVALQAYQELLPK...VTTQEG...ASV..PAgGAAPVvAAPAPVVAG--PPAGGAG..GAGAGPVEGPaAPGTVAPAGapgvaaggagaepapgavvpgagapeasvttpgET.GETGVVAAQDYAEDYDKVIALPLFGNNDDD.GDdkeADQVTMGEAES.EAPEIIVPQGINEYDVVYIKPLAGMYKTIKKQLENHVNALNTNIIDMLDSRLKKRNYFLDVLNSDLNPYKYSSSGEYIIKDPYKLLDLEKKKKLLGSYKYIGASVDKDMVTANDGLAYYQKMGDLYKKHLDEVNEQIKEVEANI...........NKQDAEIKKiesdtsktaqknqlnakkeelQKYLPFLSSIQKEYNTLVNKVHSYTDTLKKIINNCQIEKKETE...........
Q8I0U8_PLAF7/981-1536 ...................................NLGNKTKVPNPLTISTTEM.EKFYENILKNNDTYfNDDIKQFVKSNSKVITGLT.ETQKNALNDEIKKLKDTLQLSFDLYNKYKLKLDRLFNKKKELGQDKMQIKKLTLLKEQLESKLNSLNNP.HNVLQNFSVFFNKKKEAEIAETENTLENTKILLKHYKGLVKYYNGESSPLKTLSEVSIQTEDNYANLEKFRVLSKIDGKLNDNLHLGKKKLSFLSSGLHHLITELKEVIKNKNYTGNSPSENNKKVNEALKSYENFLP-...----EA...KVT..TV.VTPP-.-QPDVTPSPLSVRVSGSS..GSTKEETQIP.TSGSL----.................................LT.ELQQVVQLQNYDEEDDSLVVLPIFGESEDN.DE..yLDQVVTGEAIS.VTMDNILSGFENEYDVIYLKPLAGVYRSLKKQIEKNIFTFNLNLNDILNSRLKKRKYFLDVLESDLMQFKHISSNEYIIEDSFKLLNSEQKNTLLKSYKYIKESVENDIKFAQEGISYYEKVLAKYKDDLESIKKVIKEEKEKFpssppttppspAKTDEQKKE.....................SKFLPFLTNIETLYNNLVNKIDDYLINLKAKINDCNVEKDEAH...........
A0A0L7KDM6_PLAFX/920-1442 ......................lgknkniyqelig---------------QKSS.ENFYEKILKDSDTFyNESFTNFVKSKADDINSLNdESKRKKLEEDINKLKKTLQLSFDLYNKYKLKLERLFDKKKTVGKYKMQIKKLTLLKEQLESKLNSLNNP.KHVLQNFSVFFYKKKEAEIAETENTLENTKILLKHYKGLVKYYNGESSPLKTLSEESIQTEDNYASLENFKVLSKLEGKLKDNLNLEKKKLSYLSSGLHHLIAELKKVIKNKNYTGNSPSENNTDVNNALESYKKFLP-...---EGT...DVA..TV.VSES-.---------------GS-..-DTLEQSQPK.KPAST-HVG.................................-A.ESNTITTSQNVDDEVDDVIIVPIFGESEEDyDD...LGQVVTGEAVTpSVIDNILSKIENEYEVLYLKPLAGVYRSLKKQLENNVMTFNVNVKDILNSRFNKRENFKNVLESDLIPYKDLTSSNYVVKDPYKFLNKEKRDKFLSSYNYIKDSIDTDINFANDVLGYYKILSEKYKSDLDSIKKYIN------...........---DKQGEN.....................EKYLPFLNNIETLYKTVNDKIDLFVIHLEAKVLNYTYEKSNV-e..........
A0A024W7X9_PLAFA/822-1107 ...................................NLGNKTKVPNPLTISTTEM.EKFYENILKNNDTYfNDDIKQFVKSNSKVITGLT.ETQKNALNDEIKKLKDTLQLSFDLYNKYKLKLDRLFNKKKELGQDKMQIKKLTLLKEQLESKLNSLNNP.HNVLQNFSVFFNKKKEAEIAETENTLENTKILLKHYKGLVKYYNGESSPLKTLSEVSIQTEDNYANLEKFRVLSKIDGKLNDNLHLGKKKLSFLSSGLHHLITELKEVIKNKNYTGNSPSENNKKVNEALKSYENFLP-...----EA...KVT..TV.VTPP-.-QPDVTPSPLSVR-----..----------.---------.................................--.------------------------------.--...-----------.------------------------------------------------------------------------------------------------------------------------------------------------...........---------.....................-------------------------------------------nyn........
W4IYZ7_PLAFP/916-1471 ...................................NLGNKTKVPNPLTISTTEM.EKFYENILKNNDTYfNDDIKQFVKSNSKVITGLT.ETQKNALNDEIKKLKDTLQLSFDLYNKYKLKLDRLFNKKKELGQDKMQIKKLTLLKEQLESKLNSLNNP.HNVLQNFSVFFNKKKEAEIAETENTLENTKILLKHYKGLVKYYNGESSPLKTLSEVSIQTEDNYANLEKFRVLSKIDGKLNDNLHLGKKKLSFLSSGLHHLITELKEVIKNKNYTGNSPSENNKKVNEALKSYENFLP-...----EA...KVT..TV.VTPP-.-QPDVTPSPLSVRVSGSS..GSTKEETQIP.TSGSL----.................................LT.ELQQVVQLQNYDEEDDSLVVLPIFGESEDN.DE..yLDQVVTGEAIS.VTMDNILSGFENEYDVIYLKPLAGVYRSLKKQIEKNIFTFNLNLNDILNSRLKKRKYFLDVLESDLMQFKHISSNEYIIEDSFKLLNSEQKNTLLKSYKYIKESVENDIKFAQEGISYYEKVLAKYKDDLESIKKVIKEEKEKFpssppttppspAKTDEQKKE.....................SKFLPFLTNIETLYNNLVNKIDDYLINLKAKINDCNVEKDEAH...........
A0A1J1H3N0_PLARL/870-1400 .........................idqnseensh-----------SEEDRRQN.ENLLESYLLQSETYeNEYLISFIKSKREVINQMN.PEKEQELLNEISELREKVKLLFSNLNKYKLKLERLINKKNETLRYRAILKRKEALKEQLQKRLNRLNKQeASVLQNFSIFFNKKRENEKEKVKNMLQNNEKLMKHYKYVIKFYNGELSPLKSISNLAIQKENNYLNLEKFRALSETEEIKKKNVDLEKSIIGSLSSGLYHLLSELEKLIDNNNYNGESNDANGLSVQKALNFNADLFPE...-SSEGS...QSA..SS.I----.-NGSLSPEPSTVTNSD-P..QSPPSQEQPV.QTESA----.................................--.--QETNAITPTDGNTDSSEGSTIAASNTEN.N-...LNQATTGTSEEtEPEENVLSRFDNATSNEYLKKVAETYKTLKKETEKHINSLNSNIIDILESNFTKRNYFLNVLDYDLISFEHEFSNDYIIEDPFKVIEPETRNKLLGNYIYILGSINKDISFINENLSYFTKISQKYSHNLEQIKSIIEKKK---...........------SQD.....................EKLLPFLISFQNLYETSLNNIGNYKNALDSKVANCEQNKE---lme........
A0A679L3P5_PLAKH/1056-1359 .............................gvtvqa------SSEEEPETNIVNV.EKIYEKHLSQMDKY.NDYFIKFLESQKEKITSMT.EEQANALGAEIEALKKKVQVSLDHYGKYKLKLERFLEKKNKISNSKEHIKKLTSLKNKLERKLNFLNNP.TSVLKNYIIFFNKKKEAEKKEVENTLKNTEILLKYYKARAKYYIGEPFPLKTLSEESLQKEDNYLNLEKFRVLSRMEGRLGNNINLEKENISYLSSGLHHVFTELKEIIKNKKYTGNDHAKNTTAVKEALQAYEELLPK...VATQTA...-SL..PP.VAPPA.VVPPVVPEAEAEAEAEAE..----------.---------.................................--.------------------------------.--...-----------.------------------------------------------------------------------------------------------------------------------------------------------------...........---------.....................-------------------------------------------aepatstqpat
A0A679L3P5_PLAKH/1344-1647 ...........................eaeaeaep-------------------.--------------.-------------------.---------------------------------------------------------------------.-------------------------------------------------------------------------------------------------------------------------------------------...-----A...TST..QP.ATADT.AAPTQTPAAPTQTPAEPAtaTATTGETAAA.PA--APAPV.................................-E.VQNAEVKAQEYGEDYDKVITLPLFGNDEDD.VEdqeEKQIITGEAEN.AQPENIVPEGINEYEVVYIKPLAGMYKSIKKQLENHVAAFNTNITDMLDSRLKKRNYFLDVLDSELNPFKYSSSGEYIIKDPYKLLDLEQKKKLLGSYQYIGASVDKDLITAKDGMEYYNKMGELYKQHLEAVNAQIKEIEASVpge....qsqlNAQKEELK-.....................-KYLPFLNSIQKEYESLVNMAHTYKENLKKFINNCQIEKKETE...........
A0A653HE52_9APIC/238-451 ............................eeekeke-------------------.--------------.-------------------.---------------------------------------------------------------------.-------------------------------------------------------------------------------------------------------------------------------------------...------...---..--.-----.------------------..----------.---------.................................--.---------------------------EEE.EE...EEEKAVVENPE.ETDDAII---KREYEIKLMHPLARTYVSFKKQLIKNIDAFTSNLDDVLETRIRKRNNFVDTLLTDLTPYEHIKDNEDILNNPYKLLNYENKLKQLNGYIYVKKNIDKNITTANSGIDYCKEMITAYTKHLELIKKIINETEKDK...........TITDNDKKG.....................--FIYFLNNMVNTFESIINKLQEYTQKIEKQINVYTLKNK---gie........
W7JYM8_PLAFA/979-1534 ...................................NLGNKTKVPNPLTISTTEM.EKFYENILKNNDTYfNDDIKQFVKSNSKVITGLT.ETQKNALNDEIKKLKDTLQLSFDLYNKYKLKLDRLFNKKKELGQDKMQIKKLTLLKEQLESKLNSLNNP.HNVLQNFSVFFNKKKEAEIAETENTLENTKILLKHYKGLVKYYNGESSPLKTLSEVSIQTEDNYANLEKFRVLSKIDGKLNDNLHLGKKKLSFLSSGLHHLITELKEVIKNKNYTGNSPSENNKKVNEALKSYENFLP-...----EA...KVT..TV.VTPP-.-QPDVTPSPLSVRVSGSS..GSTKEETQIP.TSGSL----.................................LT.ELQQVVQLQNYDEEDDSLVVLPIFGESEDN.DE..yLDQVVTGEAIS.VTMDNILSGFENEYDVIYLKPLAGVYRSLKKQIEKNIFTFNLNLNDILNSRLKKRKYFLDVLESDLMQFKHISSNEYIIEDSFKLLNSEQKNTLLKSYKYIKESVENDIKFAQEGISYYEKVLAKYKDDLESIKKVIKEEKEKFpssppttppspAKTDEQKKE.....................SKFLPFLTNIETLYNNLVNKIDDYLINLKAKINDCNVEKDEAH...........
A5K724_PLAVS/1001-1576 ..................................v-GGNSEEKPE---ADTAQV.EKFYEKHLSQIDKY.NDYFQKFLESQKDEITKMD.ETKWKALGAEIEELKKKLQVSLDHYGKYKLKLERLLKKKNKISNSKDQIKKLTSLKNKLERRQNLLNNP.TSVLKNYTAFFNKKRETEKKEVENTLKNTEILLKYYKARAKYYIGEPFPLKTLSEESMQKEDNYLNLEKFRVLSRLEGRLGKNIELEKENISYLSSGLHHVLTELKEIIKNKKYSGNDHTKNIAAVKEALQAYQELIPK...VTTQEG...AST..TA.ATLPV.TVPSAVPGGL--PGAGVP..GAAAGLTPPP.PAGSVPATGpga...........................aagST.EENVAAKAQDYAEDYDKVIALPLFGNNDDD.GE...EDQVTTGEAES.EAPEILVPAGISDYDVVYLKPLAGMYKTIKKQLENHVNAFNTNITDMLDSRLKKRNYFLEVLNSDLNPFKYSSSGEYIIKDPYKLLDLEKKKKLIGSYKYIGASIDMDLATANDGVTYYNKMGELYKTHLDGVKTEIKKVEDDI...........KKQDEELKKlgnvnsqdskknefiakkaelEKYLPFLNSLQKEYESLVSKVNTYTDNLKKVINNCQLEKKEAE...........
A0A509ALB2_PLABA/1078-1611 ................................sit---TRAESEEDIPADDFEL.DNLYKSYLQRIDGN.NTEFINFIKSKKELIKALT.PEKVNQLYLEIAHLKELSEHYYDRYYKYKLKLERLYEKHEQIQVSNRQIRELSILKARLLKRKQNINGI.FYILSGYVNFFNKRREADKQYVDNALKNNDMLLKYYKARIKYFTSEAVPLKTLTKASLDRETNYLKIEKFRAYSRLELRFKKNINLGKEKISYVSGGLYHVFEEFKELLKNKNYTGKTNPDTVPEVTNAFEQYKELLPKgvtASASPA...AAT..TP.TSADA.ATQRATPESRSGSGSG-S..GSVVSSTPEE.VARSG--SG.................................--.--------------ENAVVSGSSVDDNDDD.D-...IDQIASGQSEN.AQEKNILEAFKNESEYLYARSLGITYKSLKKHMIREFSTIKEDMTTGLNNKLQKRNDFLEVLNHELDLFKDLSTNKYVIRNPYQLLDNDKKDKQIVNLKYAAKGVNEDIETTADGIKFFNKMIELYKIQLAAVKEQIDAIEAAT...........--TDKDEKK.....................-KYVPIFEDLKGLYETILGQSEEYIEVLQNRLDSYKNEKTEFE...........
A0A0L0CYS7_PLAFA/937-1491 ...................................NLGNKTKVPNPLTISTTEM.EKFYENILKNNDTYfNDDIKQFVKSNSKVITGLT.ETQKNALNDEIKKLKDTLQLSFDLYNKYKLKLDRLFNKKKELGQDKMQIKKLTLLKEQLESKLNSLNNP.HNVLQNFSVFFNKKKEAEIAETENTLENTKILLKHYKGLVKYYNGESSPLKTLSEVSIQTEDNYANLEKFRALSKIDGKLNDNLHLGKKKLSFLSSGLHHLITELKEVIKNKNYTGNSPSENNKKVNEALKSYENFLP-...----EA...KVT..TV.VTPP-.-QPDVTPSPLSVSVSGSS..GSTKEETQIP.TSGSL----.................................LT.ELQQVVQSQNYDEEDDSLVVLPIFGESEDN.DE..yLDQVVTGEAIS.VTMDNILSGFENEYDVIYLKPLAGVYRSLKKQIEKNIITFNLNLNDILNSRLKKRKYFLDVLESDLMQFKHISSNEYIIEDSFKLLNSEQKNTLLKSYKYIKESVENDIKFAQEGISYYEKVLAKYKDDLESIKKVIKEEKEFPssppt.tppspAKTDEQKKE.....................SKFLPFLTNIETLYNNLVNKIDDYLINLKAKINDCNVEKDEAH...........
A0A1A8VP40_9APIC/1005-1545 .......................trgnadddvsep------------EEKEIEV.EEFYKKYLEEVDKY.DDYFKAFLSSKKDAVNKMT.EKDWKELEEEVKTLKSRLDMSLDHYNKYKLKLGRLFKKNEKVLSSKEHIKELSILKAQLMRRQFMLNNP.RHVIHNFRVFFNKKRETEKKEVENTLKNTDALLKYYKARVKYYNGETFPLKTISEDTLEKENNYLNLEKFKLYSRLEGKLKQNINLEKENITYLSSALYHVLSELKGIIHNKKYTGNPHAANMVEVNNALNLYKDLLPK...VET--V...AST..GA.ATQTQ.-----GGEG--ASAAAAP..PAALPAAPPA.ASAAAPGTA.................................NG.ETATVAHAEDYTEDDNNVIVLPLFGKKGTH.A-...FDQVTQGEAQD.K-DDNILNEITNEYEVVYVKPLAGVYKTLKKQLEAHVTAFHSNVTNMLESRLKKRNYFLEVLNSDLTQYKHATSDNYVIRDAYKLLDFEKKKKLLSSYKYIKDSVEKDVEIATDGIDYYEKMAALYKTYLESVNAQVDAIGKTG...........DDATKATNK.....................-KFLPFLASINAMYETLLEKVNTYNSQLKSSLNSCQLEK----irv........
A0A0L7LXP3_PLAF4/959-1513 ...................................NLGNKTKVPNPLTISTTEM.EKFYENILKNNDTYfNDDIKQFVKSNSKVITGLT.ETQKNALNDEIKKLKDTLQLSFDLYNKYKLKLDRLFNKKKELGQDKMQIKKLTLLKEQLESKLNSLNNP.HNVLQNFSVFFNKKKEAEIAETENTLENTKILLKHYKGLVKYYNGESSPLKTLSEVSIQTEDNYANLEKFRVLSKIDGKLNDNLHLGKKKLSFLSSGLHHLITELKEVIKNKNYTGNSPSENNKKVNEALKSYENFLP-...----EA...KVT..TV.VTPP-.-QPDVTPSPLSVRVSGSS..GSTKEETQIP.TSGSL----.................................LT.ELQQVVQLQNYDEEDDSLVVLPIFGESEDN.DE..yLDQVVTGEAIS.VTMDNILSGFENEYDVIYLKPLAGVYRSLKKQIEKNIITFNLNLNDILNSRLKKRKYFLDVLESDLMQFKHISSNEYIIEDSFKLLNSEQKNTLLKSYKYIKESVENDIKFAQEGISYYEKVLAKYKDDLESIKKVIKEEKEFPssppt.tppspAKTDEQKKE.....................SKFLPFLTNIETLYNNLVNKIDDYLINLKAKINDCNVEKDEAH...........
A0A1A8YQM1_9APIC/959-1497 ......................aqgnadddapape-------------EKEIEV.EEFYKKYLEEVDKY.NDYFKSFLSSKKDTVNKMT.EQNWKELEEEVKTLKSKLDMSLDHYNKYKLKLGRLFKKNEKVLSSKEHIKELSILKAQLMRRQFMLNNP.RHVIHNFRLFFNKKREIEKKEVENTLKNTDALLKYYKARVKYYNGETFPLKTISDDTLEKENNYLNLEKFKLYSRLEGKLKQNINLEKENITYLSSGLYHVLAELKGIIQNKKYTGNPHAANMVEVNNALNLYKDLLPK...VETV--...---..-A.PTGPA.TQAHGVEGG-AAPAEA--..EAVAALPAAP.APGTGTANG.................................--.ETTTVTHAEDYTEDDNNVIVLPLFGKKETH.A-...LDQVTQGEAQD.K-DDNILNEITNEYEVVYVKPLAGVYKTLKKQLEAHVTAFHSNVTNMLESRLKKRNYFLEVLNSDLTPYKHVTSGNYIIRDAYKLLDFEKKKKLLSSYKYIKDSVEKDLEIATDGIDYYEKMVALYKTYLESVNAQVDAIDKTG...........DDATKTTNK.....................-KFLPFLASIKTLYEALLEKVNTYNSQLKSSLNSCQLEK----irv........
D4AFN2_PLAGO/970-1538 .............................kvtass--------SDDVTQENAINdKELYEKHLSEVGKY.DYYFKKFVESKKDEINKMD.DTNWNKLGEEIELLKKKLQVSLDHFDKYKLKLERLLTKKNKISSSKGNVKNLAKLKAKLERRQNLLNNP.TNVLKNYTIFFNKKRESEKKTIENTLKNTDILLKYYKARAKYYIGESFPLKNISKESIQKEENFLNLEKFRVLSRMESRLGKNIDLEKENISYLSSGLHHVLTELKEIIKNKSYTGSDYSKNIEEVKKALEEYKDLLPK...VETTTAspaQVTppAQ.VTPPA.QAEASQTSEVAVEPVPQE..GAAEGTSGAA.TPAPIPTSP.................................STaESTSTLSGQDDTEDDEKVIALPLFEEKMDA.YD...EEQVTMGEAEE.RQVEVIVPRDLNEYEVVYMKPLAEVYKTIKKQLENHLNAFNNNTMDMLESRLKKRNYFLSVLNSDLAPYERASSGDYIIKDPYKLLNLEKKKKLLGSYKYIDGSIDKDMATAKDGLEYFEKMTKLYKEHLVSVNEEIEKNQKEI...........DEAKKEPSDtnpst...........kvqelEKYIPFLNSIKNAYEALLNKVNNYTYNLKTVNNNLQLEKNRT-e..........
MSP1_PLAYO/1058-1591 ................................gir---SRAESEEDMPADDFEL.DNLYKSYLQQIDGN.NTEFINFIKSKKELIKALT.PEKVNQLYLEIAHLKELSEHYYDRYSTYKLKLERLYNKHEQIQLTNRQIRDLSILKARLLKRKQTLNGV.FYILNGYVNFFNKRREAEKQYVDNALKNTDMLLKYYKARTKYFTSEAVPLKTLSKASLDRESNYLKIEKFRAYSRLELRLKKNINLGKERISYVSGGLHHVFEEFKELIKDKDYTGKKNPDNAPEVTNAFEQYKELLPKgvtVSTPAV...AVT..TT.LAADA.P---ATPEG-AVPGAV-P..GAVPGAVPGA.VPGAVPGSG.................................--.--------------TDTRVAGSSVDDNEDD.D-...IYQIASGQSED.APEKDILSEFTNESLYVYTKRLGSTYKSLKKHMLREFSTIKEDMTNGLNNKSQKRNDFLEVLSHELDLFKDLSTNKYVIRNPYQLLDNDKKDKQIVNLKYATKGINEDIETTTDGIKFFNKMVELYNTQLAAVKEQIATIEAET...........NDTNKEEKK.....................-KYIPILEDLKGLYETVIGQAEEYSEELQNRLDNYKNEKAEFE...........
A0A024WQJ1_PLAFA/971-1525 ...................................NLGNKTKVPNPLTISTTEM.EKFYENILKNNDTYfNDDIKQFVKSNSKVITGLT.ETQKNALNDEIKKLKDTLQLSFDLYNKYKLKLDRLFNKKKELGQDKMQIKKLTLLKEQLESKLNSLNNP.HNVLQNFSVFFNKKKEAEIAETENTLENTKILLKHYKGLVKYYNGESSPLKTLSEVSIQTEDNYANLEKFRVLSKIDGKLNDNLHLGKKKLSFLSSGLHHLITELKEVIKNKNYTGNSPSENNKKVNEALKSYENFLP-...----EA...KVT..TV.VTPP-.-QPDVTPSPLSVRVSGSS..GSTKEETQIP.TSGSL----.................................LT.ELQQVVQSQNYDEEDDSLVVLPIFGESEDN.DE..yLDQVVTGEAIS.VTMDNILSGFENEYDVIYLKPLAGVYRSLKKQIEKNIFTFNLNLNDILNSRLKKRKYFLDVLESDLMQFKHISSNEYIIEDSFKLLNSEQKNTLLKSYKYIKESVENDIKFAQEGISYYEKVLAKYKDDLESIKKVIKEEKEFPssppt.tppspAKTDEQKKE.....................SKFLPFLTNIETLYNNLVNKIDDYLINLKAKINDCNVEKDEAH...........
A0A024VR46_PLAFA/953-1507 ...................................NLGNKTKVPNPLTISTTEM.EKFYENILKNNDTYfNDDIKQFVKSNSKVITGLT.ETQKNALNDEIKKLKDTLQLSFDLYNKYKLKLDRLFNKKKELGQDKMQIKKLTLLKEQLESKLNSLNNP.YNVLQNFSVFFNKKKEAEIAETENTLENTKILLKHYKGLVKYYNGESSPLKTLSEVSIQTEDNYANLEKFRALSKIDGKLNDNLHLGKKKLSFLSSGLHHLITELKEVIKNKNYTGNSPSENNKKVNEALKSYENFLP-...----EA...KVT..TV.VTPP-.-QPDVTPSPLSVRVSGSS..GSTKEETQIP.TSGSL----.................................LT.ELQQVVQLQNYDEEDDSLVVLPIFGESEDN.DE..yLDQVVTGEAIS.VTMDNILSGFENEYDVIYLKPLAGVYRSLKKQIEKNIFTFNLNLNDILNSRLKKRKYFLDVLESDLMQFKHISSNEYIIEDSFKLLNSEQKNTLLKSYKYIKESVENDIKFAQEGISYYEKVLAKYKDDLESIKKVIKEEKEFPssppt.tppspAKTDEQKKE.....................SKFLPFLTNIETLYNNLVNKIDDYLINLKAKINDCNVEKNEAH...........
W7KFP9_PLAFO/981-1536 ...................................NLGNKTKVPNPLTISTTEM.EKFYENILKNNDTYfNDDIKQFVKSNSKVITGLT.ETQKNALNDEIKKLKDTLQLSFDLYNKYKLKLDRLFNKKKELGQDKMQIKKLTLLKEQLESKLNSLNNP.HNVLQNFSVFFNKKKEAEIAETENTLENTKILLKHYKGLVKYYNGESSPLKTLSEVSIQTEDNYANLEKFRVLSKIDGKLNDNLHLGKKKLSFLSSGLHHLITELKEVIKNKNYTGNSPSENNKKVNEALKSYENFLP-...----EA...KVT..TV.VTPP-.-QPDVTPSPLSVRVSGSS..GSTKEETQIP.TSGSL----.................................LT.ELQQVVQLQNYDEEDDSLVVLPIFGESEDN.DE..yLDQVVTGEAIS.VTMDNILSGFENEYDVIYLKPLAGVYRSLKKQIEKNIFTFNLNLNDILNSRLKKRKYFLDVLESDLMQFKHISSNEYIIEDSFKLLNSEQKNTLLKSYKYIKESVENDIKFAQEGISYYEKVLAKYKDDLESIKKVIKEEKEKFpssppttppspAKTDEQKKE.....................SKFLPFLTNIETLYNNLVNKIDDYLINLKAKINDCNVEKDEAH...........
A0A024X9M2_PLAFC/807-1362 ...................................NLGNKTKVPNPLTISTTEM.EKFYENILKNNDTYfNDDIKQFVKSNSKVITGLT.ETQKNALNDEIKKLKDTLQLSFDLYNKYKLKLDRLFNKKKELGQDKMQIKKLTLLKEQLESKLNSLNNP.HNVLQNFSVFFNKKKEAEIAETENTLENTKILLKHYKGLVKYYNGESSPLKTLSEVSIQTEDNYANLEKFRVLSKIDGKLNDNLHLGKKKLSFLSSGLHHLITELKEVIKNKNYTGNSPSENNKKVNEALKSYENFLP-...----EA...KVT..TV.VTPP-.-QPDVTPSPLSVRVSGSS..GSTKEETQIP.TSGSL----.................................LT.ELQQVVQLQNYDEEDDSLVVLPIFGESEDN.DE..yLDQVVTGEAIS.VTMDNILSGFENEYDVIYLKPLAGVYRSLKKQIEKNIFTFNLNLNDILNSRLKKRKYFLDVLESDLMQFKHISSNEYIIEDSFKLLNSEQKNTLLKSYKYIKESVENDIKFAQEGISYYEKVLAKYKDDLESIKKVIKEEKEKFpssppttppspAKTDEQKKE.....................SKFLPFLTNIETLYNNLVNKIDDYLINLKAKINDCNVEKDEAH...........
A0A0L1I842_PLAFA/946-1501 ...................................NLGNKTKVPNPLTISTTEM.EKFYENILKNNDTYfNDDIKQFVKSNSKVITGLT.ETQKNALNDEIKKLKDTLQLSFDLYNKYKLKLDRLFNKKKELGQDKMQIKKLTLLKEQLESKLNSLNNP.HNVLQNFSVFFNKKKEAEIAETENTLENTKILLKHYKGLVKYYNGESSPLKTLSEVSIQTEDNYANLEKFRVLSKIDGKLNDNLHLGKKKLSFLSSGLHHLITELKEVIKNKNYTGNSPSENNKKVNEALKSYENFLP-...----EA...KVT..TV.VTPP-.-QPDVTPSPLSVRVSGSS..GSTKEETQIP.TSGSL----.................................LT.ELQQVVQLQNYDEEDDSLVVLPIFGESEDN.DE..yLDQVVTGEAIS.VTMDNILSGFENEYDVIYLKPLAGVYRSLKKQIEKNIFTFNLNLNDILNSRLKKRKYFLDVLESDLMQFKHISSNEYIIEDSFKLLNSEQKNTLLKSYKYIKESVENDIKFAQEGISYYEKVLAKYKDDLESIKKVIKEEKEKFpssppttppspAKTDEQKKE.....................SKFLPFLTNIETLYNNLVNKIDDYLINLKAKINDCNVEKNEAH...........
A0A024W7K7_PLAFA/382-664 dvtpksqdptksvqipkvpypngivyplpltdihn-------------------.--------------.-------------------.---------------------------------------------------------------------.-------------------------------------------------------------------------------------------------------------------------------------------...------...---..--.-----.------------------..----------.---------.................................--.--SLAADNDKNSYEDDSLVVLPIFGESEDN.DE..yLDQVVTGEAIS.VTMDNILSGFENEYDVIYLKPLAGVYRSLKKQIEKNIFTFNLNLNDILNSRLKKRKYFLDVLESDLMQFKHISSNEYIIEDSFKLLNSEQKNTLLKSYKYIKESVENDIKFAQEGISYYEKVLAKYKDDLESIKKVIKEEKEFPssppt.tppspAKTDEQKKE.....................SKFLPFLTNIETLYNNLVNKIDDYLINLKAKINDCNVEKDEAH...........
A0A1D3JMS5_PLAMA/1105-1628 ..............................qlkan------DNEDDANELDFDI.DDIYIKYLEQVSKY.DENFKNFIESKKDIINKMS.ESEWKELGEEINTLKQDIQSSFDNFGKYKLKLERLLKKKNKITSSTNHIKEYSILKAQLLRKKNILNNP.RHVLAAFVVFFNKKIEAEKKEVENALKNTDIMLKYYKARTKYYISEAFPLKTITEQSLQKEINYLHLEKFKVYSRLEGRIKKMLNLEKENITYLSGGLHHVLTELKEIINDKTYTGYTHTKNNEEVNKALNVYEELLPK..qISTEEQ...---..--.--PD-.---NALADGT--ENAT-E..G---AEVRAA.TAESL-VQG.................................--.-------EDEYPEEVDEVIVFPIVGKKEKE.NP...LDQITKGQAET.KQDDNILKPITNEYEVLYIKPLAGVYRVLRKQIGDQIDAFNSNLTNALDTRKKKRTYFLDVLNSDLIQFKHATSDSYIIKDPYKLLDVDKKAKLIGSYKYIVSAIEKDITSAENGVEYYDKMTKLYKTQLEAVKSAIAEAQKEG...........---DKKTEN.....................EKYIPFLTNMQTLYENLLNKINGNIINLKTLITNCNLEKDA--vn.........
#=GC seq_cons .........................................c..p..phsstEh.EcFYEphLcpsDsY.ND.hKpFlcSppcsIsthT.EophptLs-EIccLKcpLQlSaDhYNKYKLKL-RLapKKcclupsKhQIK+LolLKpQLpp+hN.LNNP.psVLpNFoVFFNKK+EAEhtEsENTLcNTcILLKaYKuhlKYYNGEo.PLKTLSEsSlQpE-NYhNLEKFRlLS+l-G+LpcNlpLtKcplSaLSSGLHHllTELKElIKNKsYTGNs.ucNstcVNcALpsYcshLP........pu...tsT..os.lTsP...tssssPus.uspsuuss..Gusttpsths.ssuoh......................................t.E.ppssphpsYsE--DslllLPlFGcsEDs.s-...lDQVsoGEA.s.hs.DNILsthpNEY-VlYlKPLAGVY+SLKKQlEcplhsFN.NlsDhLsSRLKKRpYFL-VLpSDLh.FKHlSSs-YIIcDsaKLLs.EpKspLLpSYKYIKcSV-pDIchAp-GIsYY-KhhshYKscLESlKc.Icc.ccph...........scsDcppKc.....................pKaLPFLssIcsLYpsLlNKlcsYh.sLKupINsCplEKsEsc...........
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