#=GF ID MTIP_N
#=GF AC PF21550.1
#=GF DE Myosin A tail domain interacting protein, N-terminal
#=GF AU Bateman A;0000-0002-6982-4660
#=GF AU Lazaro Pinto Beatriz;0000-0001-6837-2941
#=GF SE ECOD:EF19523
#=GF GA 27.00 27.00;
#=GF TC 27.10 27.20;
#=GF NC 26.50 26.90;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP Domain
#=GF CL CL0220
#=GF RC Paper describing PDB structure 2auc
#=GF RN [1]
#=GF RM 16547135
#=GF RT Structure of the MTIP-MyoA complex, a key component of the
#=GF RT malaria parasite invasion motor.
#=GF RA Bosch J, Turley S, Daly TM, Bogh SM, Villasmil ML, Roach C, Zhou
#=GF RA N, Morrisey JM, Vaidya AB, Bergman LW, Hol WG;
#=GF RL Proc Natl Acad Sci U S A. 2006;103:4852-4857.
#=GF RC Paper describing PDB structure 2qac
#=GF RN [2]
#=GF RM 17628590
#=GF RT The closed MTIP-myosin A-tail complex from the malaria parasite
#=GF RT invasion machinery.
#=GF RA Bosch J, Turley S, Roach CM, Daly TM, Bergman LW, Hol WG;
#=GF RL J Mol Biol. 2007;372:77-88.
#=GF RC Paper describing PDB structure 4aom
#=GF RN [3]
#=GF RM 22932904
#=GF RT Regulation of the Plasmodium motor complex: phosphorylation of
#=GF RT myosin A tail-interacting protein (MTIP) loosens its grip on
#=GF RT MyoA.
#=GF RA Douse CH, Green JL, Salgado PS, Simpson PJ, Thomas JC, Langsley
#=GF RA G, Holder AA, Tate EW, Cota E;
#=GF RL J Biol Chem. 2012;287:36968-36977.
#=GF RC Paper describing PDB structure 4ggn
#=GF RN [4]
#=GF RM 23831371
#=GF RT The structure of the D3 domain of Plasmodium falciparum myosin
#=GF RT tail interacting protein MTIP in complex with a nanobody.
#=GF RA Khamrui S, Turley S, Pardon E, Steyaert J, Fan E, Verlinde CL,
#=GF RA Bergman LW, Hol WG;
#=GF RL Mol Biochem Parasitol. 2013;190:87-91.
#=GF RC Paper describing PDB structure 4mzj
#=GF RN [5]
#=GF RM 25084543
#=GF RT Crystal structures of stapled and hydrogen bond surrogate
#=GF RT peptides targeting a fully buried protein-helix interaction.
#=GF RA Douse CH, Maas SJ, Thomas JC, Garnett JA, Sun Y, Cota E, Tate
#=GF RA EW;
#=GF RL ACS Chem Biol. 2014;9:2204-2209.
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC This domain is found at the N-terminal end of Myosin A tail
#=GF CC domain interacting protein from Plasmodium falciparum (MTIP) and
#=GF CC in similar eukaryotic sequences. MTIP is one of the proteins
#=GF CC that empower host cell invasion. This domain adopts an EF hand
#=GF CC configuration [1-5].
#=GF SQ 41
#=GS A5K8W6_PLAVS/71-141 AC A5K8W6.1
#=GS Q7RSF0_PLAYO/66-136 AC Q7RSF0.1
#=GS A0A024X364_PLAFC/66-136 AC A0A024X364.1
#=GS A0A2A9MDL9_9APIC/74-144 AC A0A2A9MDL9.1
#=GS B6AJ79_CRYMR/68-138 AC B6AJ79.1
#=GS Q5CWQ5_CRYPI/72-144 AC Q5CWQ5.1
#=GS A0A2A9ME68_9APIC/491-551 AC A0A2A9ME68.1
#=GS A0A1A8WHT0_PLAMA/67-137 AC A0A1A8WHT0.1
#=GS A0A1R4ABC4_BABMR/73-141 AC A0A1R4ABC4.1
#=GS A0A2C6KXZ4_9APIC/76-146 AC A0A2C6KXZ4.1
#=GS A0A1A9A267_9APIC/67-137 AC A0A1A9A267.1
#=GS V5B269_TOXGV/232-294 AC V5B269.1
#=GS A0A509ASH7_PLABA/66-136 AC A0A509ASH7.1
#=GS A0A024VMU5_PLAFA/66-136 AC A0A024VMU5.1
#=GS Q4UH60_THEAN/65-135 AC Q4UH60.1
#=GS A0A2C6KLS3_9APIC/81-149 AC A0A2C6KLS3.1
#=GS A0A0F7V1A1_TOXGV/72-142 AC A0A0F7V1A1.1
#=GS A0A384KCF1_PLAKH/67-137 AC A0A384KCF1.1
#=GS A0A024W3N2_PLAFA/143-213 AC A0A024W3N2.1
#=GS A0A1X1BLZ5_9APIC/64-134 AC A0A1X1BLZ5.1
#=GS A0A1J1HD53_PLARL/63-133 AC A0A1J1HD53.1
#=GS A0A0L1IFJ4_PLAFA/66-136 AC A0A0L1IFJ4.1
#=GS A0A653HIY5_9APIC/67-137 AC A0A653HIY5.1
#=GS W7K1J7_PLAFO/66-136 AC W7K1J7.1
#=GS L0B0T5_THEEQ/63-133 AC L0B0T5.1
#=GS A0A1D3CYQ9_9EIME/81-151 AC A0A1D3CYQ9.1
#=GS A0A1A8WAD1_9APIC/67-137 AC A0A1A8WAD1.1
#=GS K6UF09_PLACD/67-137 AC K6UF09.1
#=GS W7JUB6_PLAFA/66-136 AC W7JUB6.1
#=GS A0A1D3UAV0_9APIC/67-137 AC A0A1D3UAV0.1
#=GS J4DNI8_THEOR/63-133 AC J4DNI8.1
#=GS Q4N8F8_THEPA/65-135 AC Q4N8F8.1
#=GS F0VHG1_NEOCL/75-145 AC F0VHG1.1
#=GS A0A0L7M1B0_PLAF4/66-136 AC A0A0L7M1B0.1
#=GS A0A024WMQ7_PLAFA/66-136 AC A0A024WMQ7.1
#=GS W4J253_PLAFP/66-136 AC W4J253.1
#=GS Q8I4W8_PLAF7/66-136 AC Q8I4W8.1
#=GS A0A2A9M0K9_9APIC/738-808 AC A0A2A9M0K9.1
#=GS A0A0L7KJM5_PLAFX/66-136 AC A0A0L7KJM5.1
#=GS A0A1Y1JRJ2_PLAGO/67-137 AC A0A1Y1JRJ2.1
#=GS A0A7E4VBV3_PANRE/3-71 AC A0A7E4VBV3.1
A5K8W6_PLAVS/71-141 ...........EELDEKVDRSEAKTMFNEKSSN.GKVSVEDAS..QNARKLGLAPSSLDEKKV.RDLYGDSLTYEQYLEYLAMCVH....
Q7RSF0_PLAYO/66-136 ..........d-ELDEKVNKDDRKRYFDEKSSG.GKISIENAS..HNARRLGLAPSSKDEEKI.RELYGDNLTYDQYLEYLSMSIH....
A0A024X364_PLAFC/66-136 ...........EQLEEKVDESDVRIYFNEKSSG.GKISIDNAS..YNARKLGLAPSSIDEKKI.KELYGDNLTYEQYLEYLSICVH....
A0A2A9MDL9_9APIC/74-144 ...........EALEEMVEADEMKERFSDRASG.GKITSDDAL..VLARQLGLAPSYADKEHI.EKQSGDNLDYATFQKFVGASTH....
B6AJ79_CRYMR/68-138 .....daviee------KEENLINEMFSEVASG.GICNIKQAS..HLVHRIGLSPSNQDIEKL.ESTTGGKVTLDDFVKWTLTITH....
Q5CWQ5_CRYPI/72-144 ....siedele-----EGEADIIREMFDNASSG.GECSLDQTC..HLAHRMGLAPSKSDLEQL.NEETGGKVTYEDFERWIMSITH....
A0A2A9ME68_9APIC/491-551 afrffrslcgp---------------------K.GEVAIDQAV..VVAHSKGLAPSEEDLRNW.TAVHGPSVKLSQLEEFLSFCVH....
A0A1A8WHT0_PLAMA/67-137 ...........EELGDKVDSSEAKTFFNEKSSS.GKISIQDAS..YNARRLGLAPSSTDEKKI.KELYGENITYEQYLEYIAMCVH....
A0A1R4ABC4_BABMR/73-141 ....epieqpd------IEKSEIHKAFDSKAVS.GKVSINEVA..NLLRTLGYAPTNAELEES.AKMFGESLTLSQFQD-------icya
A0A2C6KXZ4_9APIC/76-146 ...........EALEEMVEADEMKDRFNDKASG.GKVTSDDAM..VLARQLGLAPSYEDKKNF.EQQSGDHMDYGTFQKFAAASTH....
A0A1A9A267_9APIC/67-137 ...........ENLDEKVDQSDAKIFFNENSSN.GKINIEGAS..HNARKLGLAPSSADENKI.RELYGDNLTYEQYLEYLSICVH....
V5B269_TOXGV/232-294 ........ags-------EKSQQEKDFDARAKG.GSMPQQDAG..DYARSLGFAPSN---KEI.ASL-PEKVDYKTFQDFLGVAMH....
A0A509ASH7_PLABA/66-136 ..........d-ELDEKVNKDDRKIYFDEKSSS.GKISIENAS..YNARRLGLAPSSKDEEKI.RDLYGDNLTYDQYLEYLSMTIH....
A0A024VMU5_PLAFA/66-136 ...........EQLEEKVDESDVRIYFNEKSSG.GKISIDNAS..YNARKLGLAPSSIDEKKI.KELYGDNLTYEQYLEYLSICVH....
Q4UH60_THEAN/65-135 ...........EALEEMIEVDVLEESFKKRARG.GILDVHLAG..VLARELGASPSQADLLEF.EATCGKSVNFENFKDFLAVSM-y...
A0A2C6KLS3_9APIC/81-149 ..esapasvde--------GSALKKEFEKRAKK.GMMPRNDVG..NYARSLGYAPSM---KEI.ASLPDKGVDFKSFQEFLAVAMH....
A0A0F7V1A1_TOXGV/72-142 ...........EALEEMVEADEMYARFNARASG.GKVSTGDAM..ILARQLGLAPSYADKQAF.EEKSGDNLDYASFQKFVGTSTH....
A0A384KCF1_PLAKH/67-137 ...........EELDEKVNRNEAKDMFNTKSSN.GKLRIEDAS..HNARKLGLAPSSTDEKKI.RDLYGDSLTYEQYLEYLTMCVH....
A0A024W3N2_PLAFA/143-213 ...........EQLEEKVDESDVRIYFNEKSSG.GKISIDNAS..YNARKLGLAPSSIDEKKI.KELYGDNLTYEQYLEYLSICVH....
A0A1X1BLZ5_9APIC/64-134 ...........EVVEEVIAKDELFVKFNEGATD.GMMDLKTAA..EFIRELGATPSQAELVEY.SATNGNALTFEQLKELLAICM-y...
A0A1J1HD53_PLARL/63-133 ...........ENLDEKVDKSDAKAFFNEKSRN.GKIGIEDAS..VNARKLGLAPSRTDEEKI.RERYGNNLTYDQYLEYLSLCVH....
A0A0L1IFJ4_PLAFA/66-136 ..........q-QLEEKVDESDVRIYFNEKSSG.GKISIDNAS..YNARKLGLAPSSIDEKKI.KELYGDNLTYEQYLEYLSICVH....
A0A653HIY5_9APIC/67-137 ..........g-ELYGKVDPGDAKDFFNQKAKN.NKISVQDAT..ICARKLGLAPSNNDEQKI.SELYGDNLTFDNYLEFLVMSVH....
W7K1J7_PLAFO/66-136 ..........q-QLEEKVDESDVRIYFNEKSSG.GKISIDNAS..YNARKLGLAPSSIDEKKI.KELYGDNLTYEQYLEYLSICVH....
L0B0T5_THEEQ/63-133 .........dv--LEELIEVDEMQSKFNSRASN.GFLSVHEAG..MLARELGAVPSMGDLLEF.ETTFGNAVNFEQFKELCAVS--my..
A0A1D3CYQ9_9EIME/81-151 ...........EALQEMVENDEMKQKYSDKASG.GKVSTSDAA..VLARQLGLAPSYADVEKC.AEQNGQQLDYSTFQQFAAQSTH....
A0A1A8WAD1_9APIC/67-137 ...........ENLDEKVDQSDAKIFFNENSSN.GKINIEDAS..HNARKLGLAPSSDDENKI.RELYGDNLTYEQYLEYLSICVH....
K6UF09_PLACD/67-137 ...........EELDEKVSRNEAKNMFNDKSSN.GKVTVQDAS..RNARKLGLAPSSLDEKKI.RDLYGDSLTYEQYLEYLTMCVH....
W7JUB6_PLAFA/66-136 ..........q-QLEEKVDESDVRIYFNEKSSG.GKISIDNAS..YNARKLGLAPSSIDEKKI.KELYGDNLTYEQYLEYLSICVH....
A0A1D3UAV0_9APIC/67-137 ...........ENLDEKVDQSDAKIFFNENSSN.GKINIEDAS..HNARKLGLAPSSDDENKI.RELYGDNLTYEQYLEYLSICVH....
J4DNI8_THEOR/63-133 .........gv--LEDLIEVDELENSFMNKAKR.GTLDTNMAG..ALARELGGAPSQADLLEF.EATFGNNVNFEQFKEFLAVSM-y...
Q4N8F8_THEPA/65-135 ...........EALEELIEVDVLEESFKKRAKN.GVLDVHLAG..VLARELGASPSQADLLEF.EATCGKSVNFDNFKDFLAVSM-y...
F0VHG1_NEOCL/75-145 ...........EALEEMVEADEMRDRFNERASG.GKVSTNDAM..ILARQLGLAPSYGDKKEF.EKNSGDSLDYTSFQKFVGASTH....
A0A0L7M1B0_PLAF4/66-136 ...........EQLEEKVDESDVRIYFNEKSSG.GKISIDNAS..YNARKLGLAPSSIDEKKI.KELYGDNLTYEQYLEYLSICVH....
A0A024WMQ7_PLAFA/66-136 ...........EQLEEKVDESDVRIYFNEKSSG.GKISIDNAS..YNARKLGLAPSSIDEKKI.KELYGDNLTYEQYLEYLSICVH....
W4J253_PLAFP/66-136 ...........EQLEEKVDESDVRIYFNEKSSG.GKISIDNAS..YNARKLGLAPSSIDEKKI.KELYGDNLTYEQYLEYLSICVH....
Q8I4W8_PLAF7/66-136 ..........q-QLEEKVDESDVRIYFNEKSSG.GKISIDNAS..YNARKLGLAPSSIDEKKI.KELYGDNLTYEQYLEYLSICVH....
A0A2A9M0K9_9APIC/738-808 .......drie------ISEEERRRAFEEAAEGqPQITAEKAA..QAARKLGLAPSLADVETLhKNLTGAGVDPQTFAKFCHFC--ar..
A0A0L7KJM5_PLAFX/66-136 ...........EQLEEKVDESDVRIYFNEKSSG.GKISIDNAS..YNARKLGLAPSSIDEKKI.KELYGDNLTYEQYLEYLSICVH....
A0A1Y1JRJ2_PLAGO/67-137 ...........EELDEKVDRKEAKTMFNDKSSN.GKITVEDAS..RNARKLGLAPSSTDEKKI.KELYGDNLTYEQYLEYLTICIH....
A0A7E4VBV3_PANRE/3-71 .......qyfs-----KAEIDEFRQCFNLYSSE.GFVT-NDAQlrYILRTLGCSPTVPETKRY.VKQFGASIDFAKFLEIV-----hle.
#=GC seq_cons ............tL-EcV-ps-h+hhFN-+uSu.GKlol-sAu..hsAR+LGLAPSstDccKI.c-LaGDsLTY-QalEaLuhssH....
//
