#=GF ID   Mannosyl_trans4
#=GF AC   PF15971.9
#=GF DE   DolP-mannose mannosyltransferase
#=GF AU   Eberhardt R;0000-0001-6152-1369
#=GF SE   Jackhmmer:D4GYH0
#=GF GA   33.00 33.00;
#=GF TC   33.10 33.10;
#=GF NC   31.90 31.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   23086206
#=GF RT   AglS, a Novel Component of the Haloferax volcanii
#=GF RT   N-Glycosylation Pathway, Is a Dolichol Phosphate-Mannose
#=GF RT   Mannosyltransferase.
#=GF RA   Cohen-Rosenzweig C, Yurist-Doutsch S, Eichler J;
#=GF RL   J Bacteriol. 2012;194:6909-6916.
#=GF DR   INTERPRO; IPR031897;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family catalyses the transfer of mannose from DolP-mannose
#=GF CC   to the N-linked tetrasaccharide bound to the S-layer
#=GF CC   glycoprotein to form a pentasaccharide [1].
#=GF SQ   25
#=GS A0A2R4WXY0_9EURY/56-217  AC A0A2R4WXY0.1
#=GS Q5V0R1_HALMA/18-180      AC Q5V0R1.1
#=GS A0A7D5GH10_9EURY/57-219  AC A0A7D5GH10.1
#=GS A0A6G3ZFS4_9EURY/66-228  AC A0A6G3ZFS4.1
#=GS M0B4U7_NATA1/57-219      AC M0B4U7.1
#=GS A0A6B0T7Y7_9EURY/67-229  AC A0A6B0T7Y7.1
#=GS A0A7X0REP5_9ACTN/53-224  AC A0A7X0REP5.1
#=GS A0A897NXG6_9EURY/67-229  AC A0A897NXG6.1
#=GS A0A1H4AQK8_9EURY/63-224  AC A0A1H4AQK8.1
#=GS A0A2I8VKZ2_9EURY/45-202  AC A0A2I8VKZ2.1
#=GS AGLS_HALVD/57-219        AC D4GYH0.1
#=GS A0A1I0M413_9EURY/57-219  AC A0A1I0M413.1
#=GS A0A6A9SZ73_9EURY/1-133   AC A0A6A9SZ73.1
#=GS A0A6A9T474_9EURY/65-227  AC A0A6A9T474.1
#=GS A0A1H6VJT5_9EURY/67-229  AC A0A1H6VJT5.1
#=GS A0A1H1G1J8_9EURY/69-231  AC A0A1H1G1J8.1
#=GS A0A1I0NCT4_9EURY/57-221  AC A0A1I0NCT4.1
#=GS A0A8J8CTM4_9EURY/78-239  AC A0A8J8CTM4.1
#=GS V4GXY6_9EURY/75-237      AC V4GXY6.1
#=GS A0A388TFV5_9BACT/45-209  AC A0A388TFV5.1
#=GS D2RQZ1_HALTV/57-219      AC D2RQZ1.1
#=GS D2RW44_HALTV/57-219      AC D2RW44.1
#=GS A0A1Q1FF84_9EURY/65-227  AC A0A1Q1FF84.1
#=GS A0A4P7GNW4_9ACTN/67-234  AC A0A4P7GNW4.1
#=GS W0JWG5_9EURY/57-219      AC W0JWG5.1
A0A2R4WXY0_9EURY/56-217             ......................................GGLPYVDIWDLKPPLIYYVTAGLGALTRGNVHVLHLAG.VSLTTATAVGSVLALGTITHRQTGDRKLALAAGLSLLSLPAFYQIPLGGVRPKYFALLFGLVGLYLIL..EEHP.....GLAGASTAIAAGFWHWAAIYPLLAVAIAI......LRSR-RQALWVVASGLVVTILVL-v......................................
Q5V0R1_HALMA/18-180                 ......................................GGRLYVDAWEPKLPLSYETTGVLALLSGGDMYRLHLLS.VVLMSGAVCAIVALVVMLVYDITGDDIVAPLAGLSMFLLPGFAVRPAYGFKAKYLLVLCGLLAIYLYT..RGYP.....ALSGVAAAASVGYWQAGAIFPLIVVGLAV......QRRDMRALERVVAGGLGFTIVMLL.......................................
A0A7D5GH10_9EURY/57-219             ......................................GGVPYVDVWDVNPPVPFGIAAVLSLLSGGNMLVLHGLG.STLTTLVAGSSVLLVGWVAYLVTGDDTAAVAAGLTMLVVPELFLLSPEGIRAQFYSLFFGVLALAMAL..RDRP.....FLAGAAAALSAGSWQSGVAFAPLIVGMAY......QRSGWEDALRAIAGGVVVTGAVAL.......................................
A0A6G3ZFS4_9EURY/66-228             ......................................GANLYTNIWDINPPVPFEISWIFSLVTGGNTRGMYALA.VLTSIVLGAGIILLITDVVLGMTEDVEAAMWAGLCLLVVPGFHWNASAGIHPKYLVMFLGFASLYFAI..RSRP.....ALAGACVAAATLSWQLGAFFLPLAFGLLL......SEDRITNTVWYITGGIVTTAVI--fa.....................................
M0B4U7_NATA1/57-219                 ......................................GGVPYVDVWDVNPPVPFAITAVLAVFSGGNMLVLHALG.TALTVLVAATSILLVGWVAYLVTEKHVAAIAAGLTMLIVPELLVLSLEGVRAQFYALFFGTLSLALVL..RDRP.....FLAGVAAALSAGSWQSGAVFAPLIVGMAY......QRNGGRGALSAVAGGGVVTGIVVL.......................................
A0A6B0T7Y7_9EURY/67-229             ......................................GEDLYVDIWDLKPPLIYFVTTILAALSFGNMAVLHVLS.VIVAVGTVTAGVTLLGVLTHRLTGDGFASVVAGLAMFVLTSIYSFPYAGIRPKYFAFLCAVGALILAI..DDRP.....FSAGAVGAMGAGFWQLGGPVAFLVVGIGL......QRTGKEGLLRTVAGGVAAAVF---tva....................................
A0A7X0REP5_9ACTN/53-224             gvppyvgifnsvgpladavpglairvgglvgadpvvaa--------------------------------------.RTLFLVLSACCCALVSVLARDVLASRAAGFLAPAVFLTFPEFLDLASNGPREKTVMVLFLLGALILAG..RRHW.....VLAGVSTALATLTWQPVLAVAVAG-----......------------------------aavlvaalperrlraaagfvagglltlgatvaayaasg.
A0A897NXG6_9EURY/67-229             ......................................GGTLYVDIWDLKPPLIYWVSAVLALLSFGNMAVLQIYG.IIAAVAAVSGGIIFVGLTAHRLTDDRFAALVAAGSMLLVTSLYTFPYAGIRPKYFAFLCGAGALYFAL..EDRS.....LASGVAAALAAGFWQLGGLLAFLVVAINA......DRGGARGAGRTIAGGLVVTVLTVL.......................................
A0A1H4AQK8_9EURY/63-224             ......................................GAIPYVTFWDVKPPLVFEWTALLAFFAFDNMLLLHAYH.VATTSAVAAGSVLLVGYLTTELTESSLAGFCAGAVLLAYPGFHYLAAHGFRPKYFTLFFGLAALYLHY..SGQS.....LASGVAAAAAAGFWQFGAVFPVVVLGLEY......QRTRTVPV-RALTGMAATTLVVV-t......................................
A0A2I8VKZ2_9EURY/45-202             ......................................GGRLYVDVWEPKLPLPFETTAILSLIAGDDMYLYQYLN.VGLMVLAVIGIVLLVGALTHQLTGNAFASTVAGFSMLLLPGFAIRPAYGFKAKYLLLLTGLLAIYLIL..NDHP.....FASGALAAASVGYWQLGAIFPLLVVGLAF......HRSDVRTAGAVVLGGS--------ssp....................................
AGLS_HALVD/57-219                   ......................................GKRYYIDAWDPKPPLTLELATIIAYISNGDPHLQHTLS.VVSTIVAGILLTYLISHITSEITGNQFAGLLSGIVFITFPVIHYSAVFGYEPKYFVFLFGLGSIYLSR..NPKP.....ILSGAAAAASAGMWQFAIIFPIISFGIIS......RRKSKDLILKYVFGATIIAFISLL.......................................
A0A1I0M413_9EURY/57-219             ......................................GGVPYVDVWDVNPPVPFGISAVLAVLSGGDMLVLHGLG.VTLTAVVAAASVLLVGQVAHLATGNDAAAVAAGLAMLVVPELFLLSPEGVRAQFYALFFGVLALALVL..RDRP.....FLAGAAAALSAGSWQSGAAFALLVVGMAY......QRTDRRGALAAIAGGSVVTGAVL-v......................................
A0A6A9SZ73_9EURY/1-133              ......................................------------------------------MVVLHLLS.IATAVLVVSAGVALVGLLTHRLTGDGWASLVAAGAMFTIPTLYMYPYAGLRPKYFAFACVAGSLVLAV..DERY.....GWAGALAAAAAGFWQLGLPAAGVVVAMAA......VRGGRGSAARAVGGGLVVAVLTV-a......................................
A0A6A9T474_9EURY/65-227             ......................................GATPYVDFWDLKPPLIYAVTTLLALLSGGNMAVLHVLS.VFVAVLAVYSGVVLVGVLTHRLTDDGFAAVVAGLTMFVVPTVYAFPASGIRPKYFAFCFGAAALLLAI..EDRP.....ALAGVAAATSAGFWQLGGGLAILVVAMGF......QRGGWRAAGRTVAGGLAVAVAVI-g......................................
A0A1H6VJT5_9EURY/67-229             ......................................GADLYIDIWDLKPPLIYFVTVGLAALSFGNMAVLHVLS.VIVAVGTIVAGITLVGVLTHRLTNDGFASVVAGLTMFILTSVYSFPYAGIRPKYFVFLCGVGALLLAV..DDRP.....FLAGAAGAAAAGFWQLGAPIALLVVGMSL......QRNGRDGMWRAIGGGLTVTVLTV-a......................................
A0A1H1G1J8_9EURY/69-231             ......................................GARLYVDAWEVKPPLSYETTGLLALLSGGDVYLLHLLN.VLLMMVTACGIVGLVAVLVWHSTRDRFAASLAGFSMFLLPGFLVRPAYGFKSKYALVFAGLLAIYAYT..RGYP.....ALSGAAAAASVGYWQAAIIFPCIVVGMAL......KDGDRRNLLRTIAGGVAFTAAMLL.......................................
A0A1I0NCT4_9EURY/57-221             ......................................GGVPYVDVWDVNPPVPYGVTAALAVLAGGNMLVLHGLS.VTLTVVVAATSVLLVGRVAHLATGNDTAAVAAGLTMLVVPELFVLPLLGVRSQFYALFFGVLALALILreRPRP.....FLAGAAAALSAGSWQSGVAFALLVVGIAY......QRTGRRAALSAIAGGGVVTGAVL-v......................................
A0A8J8CTM4_9EURY/78-239             ......................................GTTLYVETFEVKPPLSFETTAALSLLAGDDQLLYHYLT.VVATCVAAVCVVVLVGELAHDVTGEPAAAVAAGLSLYVLPLFALRSGFGFKAKYFVLATGLLAVWFAQ..RERD.....GLAGAAAAASVGYWQVALVFPVVVLAFAT......GR-GRRAVGRVVLGGAVVSALVL-a......................................
V4GXY6_9EURY/75-237                 ......................................GATLYTELWEIKLPLAYQTPAALALLAGGDPLVTHLLN.VGLTVAVSVGAAVLVGALVDDVTANGRAAALAGVSVLLLPGYFYLPAYGFKSKFYVVFTGLLAVWLAR..RERY.....ALSGAAAAACVGYYQAAAVFPVLAVGLAL......QYGSVRGAAEAVAGGVGMTALTV-a......................................
A0A388TFV5_9BACT/45-209             ......................................GAVLYRDVTDNKPPVLFWLAAAVTRLPGVNQINI----.LILDTLIAALSVWLFYLLACKFTANTFWLTT---AFIIFTNAHRLSQGGFLTEHYVVFFVLLAWWLWL..RDKPlpgtdILAGACLALAFLSKQTAL-----------......------------------------atcagwglyillylrrdfnlfyrglrvlggflsvlalsl
D2RQZ1_HALTV/57-219                 ......................................GGVPYVDVWDVNPPVPFGIAAVLAALSGGNMLVLHGLG.ATLTTLVAAASVLLVGWIARHVTGDDAAAIAAGLAMLVVPELFLLSPEGVRAQFYALFFGVLALALAL..RDRP.....FLAGAAAALSAGSWQSGAVFALLVVGMAY......QRNGGKDVLSVVGGGAVVTGAVVL.......................................
D2RW44_HALTV/57-219                 ......................................GGVPYVDVWDVNPPVPFAITAALAVLSGGNMYVLHGLS.VILTLLVAAANILLVGWVAFLVTGEDAAAVAAGLTMLVVPELFLLPLAGVWAQFYALFFGVLSLALAL..RDRP.....FLAGVAAALSAGSWQSGIAFAPLVVGMTY......QRTGGKDVLRAIAGGGVVTGVVVL.......................................
A0A1Q1FF84_9EURY/65-227             ......................................GATPYVDFWDLKPPLIYAVTTTLALLSGGNMAALHVLS.VVVAVAAIVAGVTLVGVLNYRLTGNGVASVAAGWTMFVVTTLYTYPWAGIRPKYLAFPFGVAALLLAV..DDRP.....LPSGAAAAVTAGFWHLGAPLALLVVAMNY......VDGDRVGLERSLAGGLTVTAVVL-a......................................
A0A4P7GNW4_9ACTN/67-234             ...................................gvp---PYVGILNRSGPLAHLVPGVGALVGRV-VGTDDLLAmRVLLALVSVASVWLAYLVARDWCGSRLAGLVAGTTMLTFGGFVHYATYGPREKTTMIFCILLTLWAIG..RRRW.....VTAGVGTALATLTWQ-GAFFPLVVAALVAllllpgRRSTLSALGRYLGAGVVVTAVTLL.......................................
W0JWG5_9EURY/57-219                 ......................................GGVPYVDVWDVNPPVPFGITAVLAVLSGGDMLVLHGLS.TALTVLVAAASVLLVGWIAYLVTEEHVAAIAAGLTMLIVPELLVLSLEGVRAQFYALFFGTLALALVL..RDRP.....FLAGVLAALSAGSWQSGAVFAPLIVGMAY......QRNGGRDALSAIAGGGLVTGIVV-g......................................
#=GC seq_cons                       ......................................Gus.YVDlWDlpPPlsatloulLAlLoGGsMhlLHhLu.VsLsllsusuuVlLVGhlsaclTucshAAlsAGloMLllPshahhshtGlRsKaaslhhGllALhLsl..R-RP.....hLAGAAAAhuAGhWQhGusFslLVVGhuh......pRsstcsshcsluGGssVTslsl.s......................................
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