#=GF ID   MccV
#=GF AC   PF17508.6
#=GF DE   Microcin V bacteriocin
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF SE   PRODOM:PD061631
#=GF GA   27.00 27.00;
#=GF TC   27.00 27.10;
#=GF NC   26.80 26.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   17653356
#=GF RT   Microcins, gene-encoded antibacterial peptides from
#=GF RT   enterobacteria.
#=GF RA   Duquesne S, Destoumieux-Garzon D, Peduzzi J, Rebuffat S;
#=GF RL   Nat Prod Rep. 2007;24:708-734.
#=GF DR   INTERPRO; IPR020280;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   Family members are bacterial microcin-V peptides MccV, also
#=GF CC   known as colicin V. MccV was the first antibiotic substance
#=GF CC   reported to be produced by E. coli. This antibacterial agent was
#=GF CC   initially named colicin V (ColV). However, on account of several
#=GF CC   characteristics (low molecular mass, non-inducible production,
#=GF CC   and dedicated export system), it became classified within the
#=GF CC   microcins. The structural gene cvaC, encodes the 103-aa MccV
#=GF CC   precursor. The dedicated export system of MccV has been well
#=GF CC   characterized and involves two genes that form the second
#=GF CC   operon. The MccV protein has an N-terminal double glycine motif
#=GF CC   which precedes the cleavage site for the precursor protein [1].
#=GF SQ   2
#=GS A0A1Z4S3P9_9NOSO/21-107  AC A0A1Z4S3P9.1
#=GS E0ULW6_GLOV7/73-112      AC E0ULW6.1
A0A1Z4S3P9_9NOSO/21-107             ahplvtglga------------AG-GGIAGAALGRSIGGKVGGVIGGVAGAIAGGVAANEL-AVYTEEFVEELQPTV.GLGLGADRKPIELPPH---------------------ysweelka
E0ULW6_GLOV7/73-112                 ladlteklte--------------------------------------------------------------ELSPSySFGVGANNKPVELPAH---------------------ysweelqa
#=GC seq_cons                       htsLsptLst................................................................sss.uhGlGAspKPlELPsH.....................YSWEELpA
//