#=GF ID MecA_N
#=GF AC PF05223.15
#=GF DE NTF2-like N-terminal transpeptidase domain
#=GF AU Bateman A;0000-0002-6982-4660
#=GF SE Bateman A
#=GF GA 22.00 22.00;
#=GF TC 22.00 22.00;
#=GF NC 21.90 21.90;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP Domain
#=GF CL CL0051
#=GF RN [1]
#=GF RM 12389036
#=GF RT Structural basis for the beta lactam resistance of PBP2a from
#=GF RT methicillin-resistant Staphylococcus aureus.
#=GF RA Lim D, Strynadka NC;
#=GF RL Nat Struct Biol 2002;9:870-876.
#=GF DR INTERPRO; IPR007887;
#=GF DR SCOP; 1mws; fa;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC The structure of this domain from MecA is known [1] Swiss:Q53707
#=GF CC and is found to be similar to that found in NTF2 Pfam:PF02136.
#=GF CC This domain seems unlikely to have an enzymatic function, and
#=GF CC its role remains unknown.
#=GF SQ 2214
#=GS A0A248TIU7_9BACI/25-147 AC A0A248TIU7.1
#=GS A0A7W5ABP8_9ACTN/26-141 AC A0A7W5ABP8.1
#=GS A0A6N2I124_9ACTN/57-165 AC A0A6N2I124.1
#=GS A0A660CHP9_9PSEU/22-132 AC A0A660CHP9.1
#=GS W4QSP5_ALKA3/27-148 AC W4QSP5.1
#=GS A0A3Q9HQE5_9FIRM/27-147 AC A0A3Q9HQE5.1
#=GS A0A6F8YMT1_9ACTN/23-138 AC A0A6F8YMT1.1
#=GS A0A0Q5QUX8_9NOCA/32-140 AC A0A0Q5QUX8.1
#=GS A0A495XJQ6_9PSEU/26-136 AC A0A495XJQ6.1
#=GS X7YCQ7_MYCKA/30-138 AC X7YCQ7.1
#=GS F5LIR9_9BACL/28-152 AC F5LIR9.1
#=GS A0A1G6NEV5_9PSEU/32-142 AC A0A1G6NEV5.1
#=GS A0A1Y6K443_9CHLR/50-168 AC A0A1Y6K443.1
#=GS A0A7Y6M158_9ACTN/51-163 AC A0A7Y6M158.1
#=GS A0A3M7TQP0_9BACI/44-171 AC A0A3M7TQP0.1
#=GS A0A1V4A5G4_9ACTN/56-165 AC A0A1V4A5G4.1
#=GS A0A1Q9T6W5_9ACTN/20-140 AC A0A1Q9T6W5.1
#=GS R9N1P7_9FIRM/46-162 AC R9N1P7.1
#=GS A0A1I1HIC2_9CLOT/35-150 AC A0A1I1HIC2.1
#=GS A0A5C4WY49_9ACTN/29-139 AC A0A5C4WY49.1
#=GS W2EPM5_9ACTN/33-143 AC W2EPM5.1
#=GS A0A6I2FIE2_9NOCA/38-147 AC A0A6I2FIE2.1
#=GS A0A1N7CCV1_9NOCA/42-149 AC A0A1N7CCV1.1
#=GS A0A4Q7Y7X0_9ACTN/31-138 AC A0A4Q7Y7X0.1
#=GS Q1CWH1_MYXXD/48-157 AC Q1CWH1.1
#=GS A0A1F1USE4_9CORY/27-135 AC A0A1F1USE4.1
#=GS A0A1J4NQG3_9ACTN/48-157 AC A0A1J4NQG3.1
#=GS A0A516X3N5_9ACTN/42-150 AC A0A516X3N5.1
#=GS A0A1I5CFY6_9ACTN/49-169 AC A0A1I5CFY6.1
#=GS A0A0X3V7V2_9ACTN/26-140 AC A0A0X3V7V2.1
#=GS A0A8J3XXR7_9ACTN/22-132 AC A0A8J3XXR7.1
#=GS A0A011RMC5_9LACT/55-178 AC A0A011RMC5.1
#=GS A0A429G104_9ACTN/32-142 AC A0A429G104.1
#=GS A0A7X1I6J7_9ACTN/66-175 AC A0A7X1I6J7.1
#=GS A0A2U1K7H5_9BACI/36-159 AC A0A2U1K7H5.1
#=GS A0A7W3RCH5_9ACTN/23-158 AC A0A7W3RCH5.1
#=GS A0A7W7FVQ4_9PSEU/50-164 AC A0A7W7FVQ4.1
#=GS R5YRK5_9FIRM/38-125 AC R5YRK5.1
#=GS R5J5G1_9CLOT/49-161 AC R5J5G1.1
#=GS A0A096A9P5_9CORY/32-140 AC A0A096A9P5.1
#=GS A0A084J8K1_9CLOT/30-146 AC A0A084J8K1.1
#=GS A0A6I0FK04_9CORY/26-134 AC A0A6I0FK04.1
#=GS A0A6I4PM40_9ACTN/20-151 AC A0A6I4PM40.1
#=GS A0A6I3L6E3_9NOCA/18-124 AC A0A6I3L6E3.1
#=GS A0A1E3SGE0_MYCIE/32-140 AC A0A1E3SGE0.1
#=GS A0A4R2DDC2_9NOCA/33-145 AC A0A4R2DDC2.1
#=GS A0A0C2ANS6_9ACTN/59-169 AC A0A0C2ANS6.1
#=GS A0A0R2EQA3_9LACO/32-148 AC A0A0R2EQA3.1
#=GS A0A4V2RM35_9NOCA/41-149 AC A0A4V2RM35.1
#=GS A0A1G8Q4R4_9NOCA/21-129 AC A0A1G8Q4R4.1
#=GS Q82HA6_STRAW/65-174 AC Q82HA6.1
#=GS A0A429BPT2_9ACTN/29-139 AC A0A429BPT2.1
#=GS A0A212QVZ5_9CHLR/48-163 AC A0A212QVZ5.1
#=GS A0A7W7XGC4_9ACTN/56-164 AC A0A7W7XGC4.1
#=GS A0A2Z3YX13_9CORY/29-137 AC A0A2Z3YX13.1
#=GS A0A0F4JS39_9ACTN/46-155 AC A0A0F4JS39.1
#=GS A0A2T0N7E0_9ACTN/29-139 AC A0A2T0N7E0.1
#=GS W9DRT1_METTI/25-138 AC W9DRT1.1
#=GS A0A160NZW8_STRLU/31-154 AC A0A160NZW8.1
#=GS A0A229UVB0_9BACL/44-189 AC A0A229UVB0.1
#=GS A0A1P8YKW1_9NOCA/44-153 AC A0A1P8YKW1.1
#=GS A0A2V3WED8_9BACI/25-155 AC A0A2V3WED8.1
#=GS D5UM28_TSUPD/30-143 AC D5UM28.1
#=GS A0A399G9D6_9ACTN/23-130 AC A0A399G9D6.1
#=GS S9P3V2_9DELT/36-145 AC S9P3V2.1
#=GS A0A8J3UP93_9ACTN/29-139 AC A0A8J3UP93.1
#=GS A0A5D0PP82_9ACTN/43-147 AC A0A5D0PP82.1
#=GS V5X9L2_MYCNE/42-150 AC V5X9L2.1
#=GS A0A2P4UQT0_9ACTN/29-134 AC A0A2P4UQT0.1
#=GS A0A1H1H9N4_9ACTN/24-131 AC A0A1H1H9N4.1
#=GS A0A7K2JZS9_9ACTN/54-165 AC A0A7K2JZS9.1
#=GS A0A7W7WCF6_9ACTN/38-151 AC A0A7W7WCF6.1
#=GS Q187V2_CLOD6/27-136 AC Q187V2.1
#=GS A0A0X3XK00_9ACTN/53-162 AC A0A0X3XK00.1
#=GS A0A2A3HP48_9ACTN/78-192 AC A0A2A3HP48.1
#=GS A0A3S9PHZ0_STRLT/55-165 AC A0A3S9PHZ0.1
#=GS A0A0U3PXW8_9ACTN/58-166 AC A0A0U3PXW8.1
#=GS R5BFF7_9CLOT/29-152 AC R5BFF7.1
#=GS A0A7W7SVG8_9ACTN/40-154 AC A0A7W7SVG8.1
#=GS A0A1S2QX46_9BACI/27-150 AC A0A1S2QX46.1
#=GS R9NGI5_9FIRM/65-180 AC R9NGI5.1
#=GS A0A024Q948_9BACI/25-150 AC A0A024Q948.1
#=GS A0A367FAX4_9ACTN/34-144 AC A0A367FAX4.1
#=GS A0A1Q4XE04_9PSEU/27-137 AC A0A1Q4XE04.1
#=GS A0A1V9KB33_9ACTN/53-162 AC A0A1V9KB33.1
#=GS A0A3E3IBP3_9FIRM/43-163 AC A0A3E3IBP3.1
#=GS A0A1I5VZF7_9FIRM/25-140 AC A0A1I5VZF7.1
#=GS A0A2N5XCD2_9ACTN/29-139 AC A0A2N5XCD2.1
#=GS A0A848KU76_9ACTN/33-142 AC A0A848KU76.1
#=GS A0A4U0HB63_9MICC/78-188 AC A0A4U0HB63.1
#=GS C9YWL3_STRSW/46-155 AC C9YWL3.1
#=GS A0A2S4YDQ8_9ACTN/65-174 AC A0A2S4YDQ8.1
#=GS A0A7J9YQA2_9ACTN/32-141 AC A0A7J9YQA2.1
#=GS A0A7K2FES6_9ACTN/63-172 AC A0A7K2FES6.1
#=GS A0A101NJW2_9ACTN/65-174 AC A0A101NJW2.1
#=GS A0A5Q0HEL0_SACSY/20-130 AC A0A5Q0HEL0.1
#=GS A0A7W7GRW6_9ACTN/26-141 AC A0A7W7GRW6.1
#=GS A0A853D7L5_9MICO/42-148 AC A0A853D7L5.1
#=GS A0A7D3Y496_9BACL/44-156 AC A0A7D3Y496.1
#=GS A0A846XSE3_9NOCA/12-121 AC A0A846XSE3.1
#=GS D2AWH4_STRRD/34-144 AC D2AWH4.1
#=GS A0A7W8YZC6_9ACTN/26-136 AC A0A7W8YZC6.1
#=GS A0A4R5AP77_9ACTN/46-156 AC A0A4R5AP77.1
#=GS A0A1H4U8I6_9ACTN/92-201 AC A0A1H4U8I6.1
#=GS A0A1H9Q8D1_9PSEU/32-140 AC A0A1H9Q8D1.1
#=GS A0A0Q7K9H9_9ACTN/31-137 AC A0A0Q7K9H9.1
#=GS M7P3D5_9BACL/24-148 AC M7P3D5.1
#=GS A0A1C6P6H0_9ACTN/60-169 AC A0A1C6P6H0.1
#=GS A0A2A9HEP1_CHLB2/43-154 AC A0A2A9HEP1.1
#=GS A0A367EL10_9ACTN/56-165 AC A0A367EL10.1
#=GS W2EPU6_9ACTN/40-146 AC W2EPU6.1
#=GS A0A543IYA2_9ACTN/34-144 AC A0A543IYA2.1
#=GS G7M395_9CLOT/35-150 AC G7M395.1
#=GS A0A1A9GIT2_9ACTN/26-138 AC A0A1A9GIT2.1
#=GS D9WMZ0_9ACTN/54-163 AC D9WMZ0.1
#=GS A0A0M8YIN3_9ACTN/58-167 AC A0A0M8YIN3.1
#=GS R6QIS6_9FIRM/30-141 AC R6QIS6.1
#=GS A0A223KQR7_9BACI/25-148 AC A0A223KQR7.1
#=GS A0A370HYX3_9NOCA/38-147 AC A0A370HYX3.1
#=GS A0A4U6QKK1_9ACTN/39-149 AC A0A4U6QKK1.1
#=GS A0A1I0FE38_9ACTN/29-139 AC A0A1I0FE38.1
#=GS G0FZW7_AMYMS/16-125 AC G0FZW7.1
#=GS A0A3A9Z192_9ACTN/37-152 AC A0A3A9Z192.1
#=GS A0A5R8YSC3_9ACTN/55-165 AC A0A5R8YSC3.1
#=GS A0A840W6J8_9ACTN/31-141 AC A0A840W6J8.1
#=GS A0A7W9QFM5_9ACTN/64-175 AC A0A7W9QFM5.1
#=GS A0A6I2H088_9DELT/104-216 AC A0A6I2H088.1
#=GS A0A401Y6R9_9ACTN/35-142 AC A0A401Y6R9.1
#=GS A0A5S4FDU4_9ACTN/34-141 AC A0A5S4FDU4.1
#=GS C0BYG4_9FIRM/45-156 AC C0BYG4.1
#=GS A0A5R9G695_9BACL/24-147 AC A0A5R9G695.1
#=GS A0A8J8H9J0_9ACTN/26-136 AC A0A8J8H9J0.1
#=GS A0A7Z2VH83_9BACL/44-183 AC A0A7Z2VH83.1
#=GS A0A168I472_9ACTN/110-209 AC A0A168I472.1
#=GS K4R8W6_STRDJ/65-174 AC K4R8W6.1
#=GS A0A7H8IGA4_9ACTN/48-157 AC A0A7H8IGA4.1
#=GS A0A6I4NHA1_9ACTN/68-178 AC A0A6I4NHA1.1
#=GS A0A255GA22_9ACTN/39-138 AC A0A255GA22.1
#=GS A0A7W3LNV9_ACTNM/32-154 AC A0A7W3LNV9.1
#=GS A0A0J6YLX1_MYCCU/29-136 AC A0A0J6YLX1.1
#=GS A0A318K4C5_9NOCA/34-142 AC A0A318K4C5.1
#=GS S5T387_9CORY/29-137 AC S5T387.1
#=GS V6L4U9_STRRC/57-169 AC V6L4U9.1
#=GS A0A2V5ITK5_9MICC/31-134 AC A0A2V5ITK5.1
#=GS A0A1L4BYJ2_9LACT/53-172 AC A0A1L4BYJ2.1
#=GS A0A4P6TR76_STRSO/57-169 AC A0A4P6TR76.1
#=GS A0A2S4XQN6_9ACTN/57-166 AC A0A2S4XQN6.1
#=GS A0A1H6A1F9_9ACTN/30-140 AC A0A1H6A1F9.1
#=GS C5EUY1_9FIRM/31-147 AC C5EUY1.1
#=GS D2ARL4_STRRD/37-147 AC D2ARL4.1
#=GS A0A238ZNX4_9ACTN/18-125 AC A0A238ZNX4.1
#=GS A0A0M8VH19_9ACTN/50-158 AC A0A0M8VH19.1
#=GS A0A852U253_9ACTN/30-140 AC A0A852U253.1
#=GS A0A3M8H7E8_9BACI/38-150 AC A0A3M8H7E8.1
#=GS A0A7I7S7D4_9MYCO/28-135 AC A0A7I7S7D4.1
#=GS A0A7W3R8T7_9ACTN/34-143 AC A0A7W3R8T7.1
#=GS S0KIV9_9ENTE/46-165 AC S0KIV9.1
#=GS A0A4U0T898_9ACTN/61-169 AC A0A4U0T898.1
#=GS A4FM95_SACEN/21-128 AC A4FM95.1
#=GS A0A1K2FIY0_9ACTN/59-171 AC A0A1K2FIY0.1
#=GS A0A285FK29_9ACTN/25-140 AC A0A285FK29.1
#=GS A0A2S3ZS51_ARTGL/37-142 AC A0A2S3ZS51.1
#=GS A0A7W7M0Y5_9ACTN/65-174 AC A0A7W7M0Y5.1
#=GS A0A4R2BBG7_9BACI/25-146 AC A0A4R2BBG7.1
#=GS E9SYY4_RHOHA/38-143 AC E9SYY4.1
#=GS A0A4R4SYU3_9ACTN/53-174 AC A0A4R4SYU3.1
#=GS A0A4V2XXX9_9ACTN/42-162 AC A0A4V2XXX9.1
#=GS H6MY28_GORPV/34-143 AC H6MY28.1
#=GS A0A1Z1WCC9_9ACTN/58-170 AC A0A1Z1WCC9.1
#=GS A0A3Q8VDP1_9ACTN/53-163 AC A0A3Q8VDP1.1
#=GS A0A1A5NZY3_9ACTN/66-175 AC A0A1A5NZY3.1
#=GS A0A1G8B484_9BACI/22-141 AC A0A1G8B484.1
#=GS A0A2T4V6Y5_VITXG/67-176 AC A0A2T4V6Y5.1
#=GS A0A402A2T4_9CHLR/145-223 AC A0A402A2T4.1
#=GS A0A1V4AB91_9ACTN/25-134 AC A0A1V4AB91.1
#=GS A0A2G5IU62_9ACTN/66-175 AC A0A2G5IU62.1
#=GS A0A368T180_9ACTN/24-131 AC A0A368T180.1
#=GS A0A150KZW0_9BACI/23-146 AC A0A150KZW0.1
#=GS A0A8J3B1P8_9ACTN/48-161 AC A0A8J3B1P8.1
#=GS A0A4R3KDF5_9BACI/26-151 AC A0A4R3KDF5.1
#=GS A0A8J3R9B0_9ACTN/68-178 AC A0A8J3R9B0.1
#=GS A0A1I0Y413_9BACI/20-143 AC A0A1I0Y413.1
#=GS A0A448N305_9ACTN/71-167 AC A0A448N305.1
#=GS G7H500_9ACTN/26-134 AC G7H500.1
#=GS A0A4Y9MPF4_9MYCO/25-131 AC A0A4Y9MPF4.1
#=GS A0A2K8PHS1_STRLA/73-182 AC A0A2K8PHS1.1
#=GS A0A8J3L784_9ACTN/34-147 AC A0A8J3L784.1
#=GS G0FLB9_AMYMS/37-148 AC G0FLB9.1
#=GS A0A3N1B039_9ACTN/26-141 AC A0A3N1B039.1
#=GS A0A239CAD7_9ACTN/34-144 AC A0A239CAD7.1
#=GS I4BNB0_MYCCN/20-127 AC I4BNB0.1
#=GS A0A285EJ40_9ACTN/40-148 AC A0A285EJ40.1
#=GS A0A6H0CNA7_9ACTN/54-163 AC A0A6H0CNA7.1
#=GS A0A7K0BMS4_9ACTN/35-144 AC A0A7K0BMS4.1
#=GS A0A0G3IM09_9MYCO/36-144 AC A0A0G3IM09.1
#=GS A0A2W2GLB9_9ACTN/31-138 AC A0A2W2GLB9.1
#=GS A0A8J3FSS3_9PSEU/43-155 AC A0A8J3FSS3.1
#=GS A0A4R6V074_9ACTN/30-140 AC A0A4R6V074.1
#=GS A0A3D9STK1_9ACTN/30-140 AC A0A3D9STK1.1
#=GS A0A0G3UW36_9ACTN/45-154 AC A0A0G3UW36.1
#=GS R6K1A7_9CLOT/46-186 AC R6K1A7.1
#=GS Q8Y9T2_LISMO/44-163 AC Q8Y9T2.1
#=GS U2DE34_9FIRM/27-148 AC U2DE34.1
#=GS A0A0T1W348_9MYCO/28-135 AC A0A0T1W348.1
#=GS A0A371JD92_9FIRM/46-158 AC A0A371JD92.1
#=GS A0A2A3Y7K1_9MICC/30-147 AC A0A2A3Y7K1.1
#=GS A0A7X9QTD1_9BACI/26-148 AC A0A7X9QTD1.1
#=GS A0A419I0G6_9PSEU/20-130 AC A0A419I0G6.1
#=GS A0A1X1R6J2_MYCBE/31-139 AC A0A1X1R6J2.1
#=GS A0A4Q4ILP7_9BACL/28-145 AC A0A4Q4ILP7.1
#=GS A0A1I2FU01_9MICO/34-147 AC A0A1I2FU01.1
#=GS A0A8J2VMP9_9BACL/28-151 AC A0A8J2VMP9.1
#=GS A0A223S6N1_9ACTN/61-168 AC A0A223S6N1.1
#=GS A0A291QA99_9ACTN/57-164 AC A0A291QA99.1
#=GS A0A1Y4SGX1_9FIRM/38-144 AC A0A1Y4SGX1.1
#=GS A0A5C8NV57_9BACI/27-156 AC A0A5C8NV57.1
#=GS A0A1B1ZRA9_9PSEU/38-152 AC A0A1B1ZRA9.1
#=GS A0A0U3I0N3_9MICC/50-137 AC A0A0U3I0N3.1
#=GS A0A1C6V6G8_9ACTN/34-148 AC A0A1C6V6G8.1
#=GS A0A0H4NWD9_9BACI/28-151 AC A0A0H4NWD9.1
#=GS A0A5N8XUG9_9ACTN/55-164 AC A0A5N8XUG9.1
#=GS A0A366E2S2_9NOCA/27-135 AC A0A366E2S2.1
#=GS W4QBP4_9BACI/24-148 AC W4QBP4.1
#=GS A0A7K1KWT8_9ACTN/20-140 AC A0A7K1KWT8.1
#=GS D6K387_9ACTN/53-162 AC D6K387.1
#=GS A0A7K0BSN2_9ACTN/29-134 AC A0A7K0BSN2.1
#=GS A0A6G2BAW1_9ACTN/57-168 AC A0A6G2BAW1.1
#=GS S2XNI2_9BACL/26-150 AC S2XNI2.1
#=GS A0A6I4N193_9ACTN/55-164 AC A0A6I4N193.1
#=GS A0A2T0MM19_9ACTN/33-143 AC A0A2T0MM19.1
#=GS A0A2M9JPK1_9ACTN/56-165 AC A0A2M9JPK1.1
#=GS A0A6H9YEM0_9ACTN/34-143 AC A0A6H9YEM0.1
#=GS A0A1G6L8W4_9ACTN/32-140 AC A0A1G6L8W4.1
#=GS A0A0Q8PYF6_9ACTN/48-149 AC A0A0Q8PYF6.1
#=GS A0A8J3FQ91_9ACTN/25-140 AC A0A8J3FQ91.1
#=GS A0A543CDF2_9ACTN/33-141 AC A0A543CDF2.1
#=GS A0A0U1QQ29_9BACL/28-144 AC A0A0U1QQ29.1
#=GS A0A372STR1_9FIRM/34-148 AC A0A372STR1.1
#=GS A0A1I6C621_9BACI/23-145 AC A0A1I6C621.1
#=GS A0A7W9PU18_9ACTN/53-162 AC A0A7W9PU18.1
#=GS A0A1A0TCW0_9MYCO/35-143 AC A0A1A0TCW0.1
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