#=GF ID MenC_N
#=GF AC PF21508.1
#=GF DE MenC, N-terminal domain
#=GF AU Bateman A;0000-0002-6982-4660
#=GF AU Chuguransky S;0000-0002-0520-0736
#=GF SE ECOD:EF16024
#=GF GA 27.30 27.30;
#=GF TC 27.30 27.30;
#=GF NC 27.20 27.20;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP Domain
#=GF CL CL0227
#=GF RC Paper describing PDB structure 1fhu
#=GF RN [1]
#=GF RM 10978150
#=GF RT Evolution of enzymatic activity in the enolase superfamily:
#=GF RT structure of o-succinylbenzoate synthase from Escherichia coli
#=GF RT in complex with Mg2+ and o-succinylbenzoate.
#=GF RA Thompson TB, Garrett JB, Taylor EA, Meganathan R, Gerlt JA,
#=GF RA Rayment I;
#=GF RL Biochemistry. 2000;39:10662-10676.
#=GF RC Paper describing PDB structure 1r6w
#=GF RN [2]
#=GF RM 14661953
#=GF RT Evolution of enzymatic activity in the enolase superfamily:
#=GF RT structural and mutagenic studies of the mechanism of the
#=GF RT reaction catalyzed by o-succinylbenzoate synthase from
#=GF RT Escherichia coli.
#=GF RA Klenchin VA, Taylor Ringia EA, Gerlt JA, Rayment I;
#=GF RL Biochemistry. 2003;42:14427-14433.
#=GF RC Paper describing PDB structure 2ofj
#=GF RN [3]
#=GF RM 17503785
#=GF RT Stability for function trade-offs in the enolase superfamily
#=GF RT "catalytic module".
#=GF RA Nagatani RA, Gonzalez A, Shoichet BK, Brinen LS, Babbitt PC;
#=GF RL Biochemistry. 2007;46:6688-6695.
#=GF RC Paper describing PDB structure 2ozt
#=GF RN [4]
#=GF RM 24872444
#=GF RT Loss of quaternary structure is associated with rapid sequence
#=GF RT divergence in the OSBS family.
#=GF RA Odokonyero D, Sakai A, Patskovsky Y, Malashkevich VN, Fedorov
#=GF RA AA, Bonanno JB, Fedorov EV, Toro R, Agarwal R, Wang C, Ozerova
#=GF RA ND, Yew WS, Sauder JM, Swaminathan S, Burley SK, Almo SC,
#=GF RA Glasner ME;
#=GF RL Proc Natl Acad Sci U S A. 2014;111:8535-8540.
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC MenC (o-succinylbenzoate synthase OSBS converts
#=GF CC 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to
#=GF CC 2-succinylbenzoate (OSB). It belongs to the enolase superfamily
#=GF CC [1-4]. This entry represents the N-terminal domain of MenC.
#=GF SQ 653
#=GS K9U4Y5_CHRTP/16-96 AC K9U4Y5.1
#=GS A0A011MYG4_9PROT/3-80 AC A0A011MYG4.1
#=GS A0A252CYT6_9NOSO/17-98 AC A0A252CYT6.1
#=GS A0A507Z8F5_9FLAO/9-97 AC A0A507Z8F5.1
#=GS A0A4R3MSP8_9GAMM/5-107 AC A0A4R3MSP8.1
#=GS A0A1B7JJW9_9GAMM/1-95 AC A0A1B7JJW9.1
#=GS D3RPJ0_ALLVD/4-106 AC D3RPJ0.1
#=GS A0A2M8RVC1_9PAST/3-102 AC A0A2M8RVC1.1
#=GS F8KWF2_PARAV/3-99 AC F8KWF2.1
#=GS R5CYX3_9BACT/21-102 AC R5CYX3.1
#=GS E0SE01_DICD3/1-95 AC E0SE01.1
#=GS A0A316TSV3_9BACT/1-77 AC A0A316TSV3.1
#=GS A0A2V4BLE8_9FLAO/1-97 AC A0A2V4BLE8.1
#=GS A0A0H5ZAG8_VIBCL/1-96 AC A0A0H5ZAG8.1
#=GS A0A4S8RGY4_9FLAO/2-97 AC A0A4S8RGY4.1
#=GS A0A2V3IKF8_9FLOR/306-388 AC A0A2V3IKF8.1
#=GS F9Q873_9PAST/3-101 AC F9Q873.1
#=GS A0A3N6NTV2_9CYAN/3-98 AC A0A3N6NTV2.1
#=GS A0A4Q7EF98_9CYAN/2-96 AC A0A4Q7EF98.1
#=GS A0A0G3CL31_9GAMM/1-95 AC A0A0G3CL31.1
#=GS B0JIV6_MICAN/5-97 AC B0JIV6.1
#=GS A0A1Q4RT26_9CYAN/2-95 AC A0A1Q4RT26.1
#=GS A0A014MAE2_9GAMM/1-96 AC A0A014MAE2.1
#=GS E6SWZ8_BACT6/19-100 AC E6SWZ8.1
#=GS D4ZEF9_SHEVD/16-136 AC D4ZEF9.1
#=GS B1ZW04_OPITP/1-96 AC B1ZW04.1
#=GS A0A6H0T4Q4_9PAST/1-97 AC A0A6H0T4Q4.1
#=GS Q2JNF3_SYNJB/16-106 AC Q2JNF3.1
#=GS A0A0L8V9G0_9BACT/1-96 AC A0A0L8V9G0.1
#=GS A0A3N9TIX7_9VIBR/1-96 AC A0A3N9TIX7.1
#=GS A0A0A5HV38_PHOS4/1-96 AC A0A0A5HV38.1
#=GS K9QLR9_NOSS7/14-110 AC K9QLR9.1
#=GS G1WAR2_9BACT/19-101 AC G1WAR2.1
#=GS A0A8J7KZK6_9NOST/6-99 AC A0A8J7KZK6.1
#=GS A0A090V243_PSEVU/1-94 AC A0A090V243.1
#=GS D3UWP3_XENBS/1-100 AC D3UWP3.1
#=GS A0A0E3YV48_9BACT/1-102 AC A0A0E3YV48.1
#=GS A0A0J8VKN9_9ENTR/1-95 AC A0A0J8VKN9.1
#=GS A0A0F5F0X3_AVIPA/1-100 AC A0A0F5F0X3.1
#=GS A0A1G8XDH6_9GAMM/1-96 AC A0A1G8XDH6.1
#=GS A0A366W0D8_9GAMM/14-111 AC A0A366W0D8.1
#=GS B7K2D8_RIPO1/9-98 AC B7K2D8.1
#=GS A0A8J7DM17_9CYAN/4-98 AC A0A8J7DM17.1
#=GS A0A2M8GVL5_9VIBR/1-96 AC A0A2M8GVL5.1
#=GS A0A1Z5KGA6_FISSO/1445-1507 AC A0A1Z5KGA6.1
#=GS A0A563VIR5_9CYAN/4-81 AC A0A563VIR5.1
#=GS A0A1D7Y283_9FLAO/1-97 AC A0A1D7Y283.1
#=GS K9T4D5_9CYAN/10-98 AC K9T4D5.1
#=GS A0A5M8FUE1_9GAMM/5-81 AC A0A5M8FUE1.1
#=GS A0A290QAC5_9BACT/4-83 AC A0A290QAC5.1
#=GS A0A378CR74_KLEPR/1-79 AC A0A378CR74.1
#=GS A0A3M8FQW6_9BACT/1-104 AC A0A3M8FQW6.1
#=GS A0A2N1G8P7_9FLAO/1-97 AC A0A2N1G8P7.1
#=GS A0A1M4ZXM9_9BACE/22-102 AC A0A1M4ZXM9.1
#=GS A0A1D8AY57_9BACT/5-97 AC A0A1D8AY57.1
#=GS A0A4P9VPT9_9GAMM/5-92 AC A0A4P9VPT9.1
#=GS E3BHQ0_9VIBR/1-96 AC E3BHQ0.1
#=GS A0A250B587_9GAMM/5-99 AC A0A250B587.1
#=GS A0A0H3K6E2_SYNP6/14-97 AC A0A0H3K6E2.1
#=GS A0A2R4X114_9EURY/1-97 AC A0A2R4X114.1
#=GS A0A098C2M2_9BACT/23-101 AC A0A098C2M2.1
#=GS A0A180FE26_9BACT/31-112 AC A0A180FE26.1
#=GS W0JLD7_9EURY/4-99 AC W0JLD7.1
#=GS A0A553AG09_9FLAO/1-97 AC A0A553AG09.1
#=GS A0A1R4I4E7_9GAMM/2-89 AC A0A1R4I4E7.1
#=GS A0A090IF12_9GAMM/38-121 AC A0A090IF12.1
#=GS A0A1X7AMF9_9GAMM/2-103 AC A0A1X7AMF9.1
#=GS Q2S2V3_SALRD/3-85 AC Q2S2V3.1
#=GS A0A2S1SJL7_9FLAO/1-97 AC A0A2S1SJL7.1
#=GS E9CKG6_9GAMM/5-99 AC E9CKG6.1
#=GS A0A1Y4HWA1_9BACT/21-101 AC A0A1Y4HWA1.1
#=GS A0A380TPV8_9PAST/3-102 AC A0A380TPV8.1
#=GS A0A1G5BQW4_9FLAO/1-97 AC A0A1G5BQW4.1
#=GS Q1AS25_RUBXD/1-71 AC Q1AS25.1
#=GS D3VJ45_XENNA/1-100 AC D3VJ45.1
#=GS A0A6N4WX07_9BACT/6-97 AC A0A6N4WX07.1
#=GS A0A7I4EG89_PHYPA/1019-1095 AC A0A7I4EG89.1
#=GS A0A2I8Q269_9ENTR/1-95 AC A0A2I8Q269.1
#=GS A0A2A8D356_9BACT/4-113 AC A0A2A8D356.1
#=GS A0A139X7F6_9CYAN/14-98 AC A0A139X7F6.1
#=GS A0A2T1CQL5_9CYAN/9-100 AC A0A2T1CQL5.1
#=GS A0A377I193_HAEPH/1-91 AC A0A377I193.1
#=GS A0A0U5JBL4_9BACT/4-99 AC A0A0U5JBL4.1
#=GS A0A1J1LQB5_9CYAN/4-98 AC A0A1J1LQB5.1
#=GS A0A2T6CMA4_9BACT/4-98 AC A0A2T6CMA4.1
#=GS A0A2T3MVE7_9GAMM/1-96 AC A0A2T3MVE7.1
#=GS A0A1Y2PCX6_9FLAO/1-98 AC A0A1Y2PCX6.1
#=GS A0A1X1MSA1_9VIBR/1-96 AC A0A1X1MSA1.1
#=GS A0A2P8WJC6_9CYAN/7-96 AC A0A2P8WJC6.1
#=GS A0A533U0X2_CHLSQ/3-101 AC A0A533U0X2.1
#=GS R8AP52_PLESH/1-95 AC R8AP52.1
#=GS MENC_CITK8/1-94 AC A8ADX2.1
#=GS A0A2T6DQK7_9BACT/4-82 AC A0A2T6DQK7.1
#=GS A0A090T3P5_9VIBR/10-105 AC A0A090T3P5.1
#=GS A0A1Y0D0A2_9GAMM/1-86 AC A0A1Y0D0A2.1
#=GS I3D6F4_9PAST/3-102 AC I3D6F4.1
#=GS A0A3S5K2H8_CHLFR/5-98 AC A0A3S5K2H8.1
#=GS M1WRY0_9NOST/8-98 AC M1WRY0.1
#=GS B5JH41_9BACT/6-96 AC B5JH41.1
#=GS A0A6B0T8B6_9EURY/3-95 AC A0A6B0T8B6.1
#=GS A0A4R2N4B6_9PAST/1-98 AC A0A4R2N4B6.1
#=GS K9VQ98_9CYAN/9-98 AC K9VQ98.1
#=GS L0DWC3_THIND/9-93 AC L0DWC3.1
#=GS C5BMH4_TERTT/5-108 AC C5BMH4.1
#=GS A0A2T1M097_9CHRO/2-98 AC A0A2T1M097.1
#=GS A0A3N4VY46_9PAST/1-96 AC A0A3N4VY46.1
#=GS A0A448QPB5_ACTEU/1-96 AC A0A448QPB5.1
#=GS A0A0A8VIL6_YERRU/1-95 AC A0A0A8VIL6.1
#=GS A0A327RGZ0_9FLAO/5-97 AC A0A327RGZ0.1
#=GS A0A8J6SRK2_9CYAN/10-98 AC A0A8J6SRK2.1
#=GS X5DIU3_9BACT/1-97 AC X5DIU3.1
#=GS A0A094JHV6_9GAMM/3-112 AC A0A094JHV6.1
#=GS G8QGD3_AZOOP/3-107 AC G8QGD3.1
#=GS A0A2K8KNN7_9GAMM/3-92 AC A0A2K8KNN7.1
#=GS A8FPR4_SHESH/3-118 AC A8FPR4.1
#=GS A0A1G7YMS2_9FLAO/1-97 AC A0A1G7YMS2.1
#=GS D0IBW9_GRIHO/1-96 AC D0IBW9.1
#=GS R4W079_9EURY/3-97 AC R4W079.1
#=GS A0A090SRN0_9VIBR/1-96 AC A0A090SRN0.1
#=GS A0A662ZJS2_9GAMM/1-101 AC A0A662ZJS2.1
#=GS D4E3S0_SEROD/5-99 AC D4E3S0.1
#=GS A0A1R4B3E1_9VIBR/1-96 AC A0A1R4B3E1.1
#=GS A0A380YW75_BACFN/20-101 AC A0A380YW75.1
#=GS A0A859RHM4_9ENTR/1-95 AC A0A859RHM4.1
#=GS A0A844M6D8_9CYAN/4-98 AC A0A844M6D8.1
#=GS A0A5A5TBN3_9CHLR/9-108 AC A0A5A5TBN3.1
#=GS G2Z7D2_FLABF/1-97 AC G2Z7D2.1
#=GS A0A218QM68_9CYAN/17-97 AC A0A218QM68.1
#=GS U4KDA1_9VIBR/1-96 AC U4KDA1.1
#=GS A0A370EYX8_9FLAO/3-97 AC A0A370EYX8.1
#=GS R5JSJ7_9BACE/17-101 AC R5JSJ7.1
#=GS A0A1Y1R3W6_9GAMM/3-86 AC A0A1Y1R3W6.1
#=GS A0A5B8YLL8_9FLAO/2-97 AC A0A5B8YLL8.1
#=GS A0A2N0WYV9_9GAMM/10-102 AC A0A2N0WYV9.1
#=GS K9S510_9CYAN/4-99 AC K9S510.1
#=GS K9TFA5_9CYAN/9-98 AC K9TFA5.1
#=GS A0A402AF54_9CHLR/17-100 AC A0A402AF54.1
#=GS Q0YUC8_9CHLB/2-101 AC Q0YUC8.1
#=GS A0A1H6TZP0_9EURY/3-92 AC A0A1H6TZP0.1
#=GS A0A4P7J1V6_9ENTR/1-94 AC A0A4P7J1V6.1
#=GS A0A521DAQ5_9BACT/4-92 AC A0A521DAQ5.1
#=GS A0A345H5P3_9FLAO/8-97 AC A0A345H5P3.1
#=GS A0A521ADP7_9BACT/1-106 AC A0A521ADP7.1
#=GS A0A1V3TUS3_9PAST/1-96 AC A0A1V3TUS3.1
#=GS A0A2A2TPB3_9CYAN/19-98 AC A0A2A2TPB3.1
#=GS A0A6M0K619_9GAMM/3-104 AC A0A6M0K619.1
#=GS A0A0A2W5D7_BEABA/1811-1905 AC A0A0A2W5D7.1
#=GS A0A7Y5NK51_9DELT/2-78 AC A0A7Y5NK51.1
#=GS A0A5J5G0L9_9GAMM/1-95 AC A0A5J5G0L9.1
#=GS A0A1G7I3S9_9FLAO/1-97 AC A0A1G7I3S9.1
#=GS A0A4R6VI20_9PAST/3-102 AC A0A4R6VI20.1
#=GS A0A1I2CSG7_9BACT/2-96 AC A0A1I2CSG7.1
#=GS MENC_ECOSE/1-94 AC B6I7K5.1
#=GS A0A1I5K964_9BACT/20-99 AC A0A1I5K964.1
#=GS A0A415E2J7_9BACT/24-105 AC A0A415E2J7.1
#=GS A1SRE3_PSYIN/10-105 AC A1SRE3.1
#=GS A7MV77_VIBC1/1-96 AC A7MV77.1
#=GS A0A2P8QZK2_9PROT/9-97 AC A0A2P8QZK2.1
#=GS K9PEH8_9CYAN/14-97 AC K9PEH8.1
#=GS A0A1C0VYT7_9CYAN/11-98 AC A0A1C0VYT7.1
#=GS A0A1V1ZFI9_9FLAO/1-97 AC A0A1V1ZFI9.1
#=GS Q8KBE1_CHLTE/4-107 AC Q8KBE1.1
#=GS A0A1L5YBN2_9EUKA/10-104 AC A0A1L5YBN2.1
#=GS A0A1S8CMF5_9GAMM/5-99 AC A0A1S8CMF5.1
#=GS Q1D6J8_MYXXD/5-97 AC Q1D6J8.1
#=GS MENC_PHOLL/1-95 AC Q7N2K6.1
#=GS A0A1T0B7E1_9PAST/1-100 AC A0A1T0B7E1.1
#=GS A0A1U7IQ12_9CYAN/3-98 AC A0A1U7IQ12.1
#=GS A0A8J6WU21_9CYAN/6-104 AC A0A8J6WU21.1
#=GS B3EG71_CHLL2/3-101 AC B3EG71.1
#=GS I9GYE5_9BACE/4-101 AC I9GYE5.1
#=GS A0A5B7SPR1_9FLAO/18-97 AC A0A5B7SPR1.1
#=GS A0A420XHK2_9PAST/1-96 AC A0A420XHK2.1
#=GS A0A8J7AYN7_9CYAN/12-99 AC A0A8J7AYN7.1
#=GS A0A0B8NRP9_9VIBR/1-70 AC A0A0B8NRP9.1
#=GS A0A5B8NL19_9CHRO/1-97 AC A0A5B8NL19.1
#=GS A0A1A7KNC4_9FLAO/1-97 AC A0A1A7KNC4.1
#=GS K1LPP0_9FLAO/50-147 AC K1LPP0.1
#=GS A0A401ZXD1_9CHLR/14-116 AC A0A401ZXD1.1
#=GS L1N6S0_9BACT/21-102 AC L1N6S0.1
#=GS A0A4R2MWN6_9PAST/1-100 AC A0A4R2MWN6.1
#=GS A0A1Y6IPS7_9VIBR/1-96 AC A0A1Y6IPS7.1
#=GS A0A178KA47_9GAMM/1-96 AC A0A178KA47.1
#=GS A0A2A5T279_9GAMM/2-97 AC A0A2A5T279.1
#=GS A0A2R5FT96_NOSCO/12-99 AC A0A2R5FT96.1
#=GS A0A377ZA12_KLEPO/1-95 AC A0A377ZA12.1
#=GS A0A071LNV2_9ENTR/1-95 AC A0A071LNV2.1
#=GS A0A3P3WE74_9FLAO/4-97 AC A0A3P3WE74.1
#=GS A0A1Y6L0K7_9GAMM/1-96 AC A0A1Y6L0K7.1
#=GS A0A7Z2T203_9VIBR/1-96 AC A0A7Z2T203.1
#=GS A0A1V3IZN9_9PAST/3-102 AC A0A1V3IZN9.1
#=GS A0A856MQE0_9CYAN/5-98 AC A0A856MQE0.1
#=GS A0A6B2FJH4_9ENTR/1-95 AC A0A6B2FJH4.1
#=GS D6TM01_KTERA/3-109 AC D6TM01.1
#=GS B0C5M2_ACAM1/3-96 AC B0C5M2.1
#=GS A0A1Z4IPL0_9CYAN/8-97 AC A0A1Z4IPL0.1
#=GS A0A2J8GSX8_VIBDI/1-96 AC A0A2J8GSX8.1
#=GS A0A5S9IQQ0_9BACT/3-113 AC A0A5S9IQQ0.1
#=GS A0A328WKE7_9FLAO/1-97 AC A0A328WKE7.1
#=GS A1BI77_CHLPD/4-101 AC A1BI77.1
#=GS E1SVA2_FERBD/1-88 AC E1SVA2.1
#=GS MENC_PROMH/1-95 AC B4EZ39.1
#=GS A0KFN5_AERHH/1-89 AC A0KFN5.1
#=GS A0A420E6R3_9ALTE/6-102 AC A0A420E6R3.1
#=GS A0A1Z5JQW7_FISSO/1437-1531 AC A0A1Z5JQW7.1
#=GS A0A0M0HNV7_VIBNE/1-96 AC A0A0M0HNV7.1
#=GS A0A3N1J9I6_9ENTR/1-95 AC A0A3N1J9I6.1
#=GS A0A6G8D117_9VIBR/1-96 AC A0A6G8D117.1
#=GS A0A4R1FU83_9PAST/2-101 AC A0A4R1FU83.1
#=GS A0A419W8Y9_9BACT/4-96 AC A0A419W8Y9.1
#=GS A0A0M1JRA7_9CYAN/9-98 AC A0A0M1JRA7.1
#=GS G2FC95_9GAMM/3-94 AC G2FC95.1
#=GS F0IDX4_9FLAO/1-99 AC F0IDX4.1
#=GS A0A370R2G8_9GAMM/1-95 AC A0A370R2G8.1
#=GS A0A255T367_9BACT/20-101 AC A0A255T367.1
#=GS A0A485AWY8_KLUCR/1-56 AC A0A485AWY8.1
#=GS D5EKE4_CORAD/18-94 AC D5EKE4.1
#=GS A0A8J7ZUP0_9EURY/4-97 AC A0A8J7ZUP0.1
#=GS M4U7T7_9GAMM/1-96 AC M4U7T7.1
#=GS Q3B616_CHLL3/3-101 AC Q3B616.1
#=GS A0A0F7K0U8_9GAMM/3-105 AC A0A0F7K0U8.1
#=GS A0A4R2FJP8_9GAMM/3-112 AC A0A4R2FJP8.1
#=GS A0A2U8E6E2_9BACT/15-110 AC A0A2U8E6E2.1
#=GS K9XQ34_STAC7/8-100 AC K9XQ34.1
#=GS A0A4S4A4K7_9FLAO/6-102 AC A0A4S4A4K7.1
#=GS A0A2N5EPT7_9GAMM/1-95 AC A0A2N5EPT7.1
#=GS K9XGM2_9CHRO/6-101 AC K9XGM2.1
#=GS C4L9G0_TOLAT/1-89 AC C4L9G0.1
#=GS A0A1H0DIC6_9BACT/18-99 AC A0A1H0DIC6.1
#=GS I5B766_9DELT/2-96 AC I5B766.1
#=GS A0A317ZG98_9BACT/16-92 AC A0A317ZG98.1
#=GS I2B787_SHIBC/1-95 AC I2B787.1
#=GS A0A1B6YDT0_9BACT/1-103 AC A0A1B6YDT0.1
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