#=GF ID Mistic
#=GF AC PF11458.12
#=GF DE Membrane-integrating protein Mistic
#=GF AU Pollington J;0000-0002-8158-8998
#=GF SE pdb_1ygm
#=GF GA 26.00 26.00;
#=GF TC 26.00 36.40;
#=GF NC 25.60 21.10;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 15731457
#=GF RT NMR structure of Mistic, a membrane-integrating protein for
#=GF RT membrane protein expression.
#=GF RA Roosild TP, Greenwald J, Vega M, Castronovo S, Riek R, Choe S;
#=GF RL Science. 2005;307:1317-1321.
#=GF RN [2]
#=GF RM 16704729
#=GF RT Characterization of the family of Mistic homologues.
#=GF RA Roosild TP, Vega M, Castronovo S, Choe S;
#=GF RL BMC Struct Biol. 2006;6:10.
#=GF DR INTERPRO; IPR021078;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC Mistic is an integral membrane protein that folds autonomously
#=GF CC into the membrane [1].The protein forms a helical bundle with a
#=GF CC polar lipid-facing surface. Mistic can be used for high-level
#=GF CC production of other membrane proteins in their native
#=GF CC conformations [1].
#=GF SQ 58
#=GS A0A428N453_9BACI/43-116 AC A0A428N453.1
#=GS A0A161WD43_9BACI/7-80 AC A0A161WD43.1
#=GS A0A4R6U6N2_9BACI/7-80 AC A0A4R6U6N2.1
#=GS A0A0K0GC12_9FIRM/7-73 AC A0A0K0GC12.1
#=GS A0A3A1QWN8_9BACI/9-82 AC A0A3A1QWN8.1
#=GS A0A0L0QMH0_VIRPA/7-73 AC A0A0L0QMH0.1
#=GS A0A1B1Z7B0_9BACI/1-63 AC A0A1B1Z7B0.1
#=GS A0A1H0WYF5_9BACI/7-80 AC A0A1H0WYF5.1
#=GS I8AJB9_9BACI/7-80 AC I8AJB9.1
#=GS A0A1I0CD54_9BACI/7-73 AC A0A1I0CD54.1
#=GS A0A223KUB7_9BACI/7-80 AC A0A223KUB7.1
#=GS A0A235F4E4_9BACI/7-80 AC A0A235F4E4.1
#=GS A0A7X2J0I9_9BACI/7-80 AC A0A7X2J0I9.1
#=GS A0A263BS01_9BACI/7-80 AC A0A263BS01.1
#=GS A0A6N8CLJ7_9BACI/2-73 AC A0A6N8CLJ7.1
#=GS A0A549YJB8_9BACI/7-73 AC A0A549YJB8.1
#=GS A0A3R9P774_9BACI/16-89 AC A0A3R9P774.1
#=GS A0A1J6WA39_9BACI/7-80 AC A0A1J6WA39.1
#=GS A6CLW8_9BACI/7-80 AC A6CLW8.1
#=GS A0A0N0VNH2_9BACI/14-87 AC A0A0N0VNH2.1
#=GS A0A7H8S4L3_9BACI/7-73 AC A0A7H8S4L3.1
#=GS A0A1I0JIG5_9BACI/7-73 AC A0A1I0JIG5.1
#=GS A0A8J2YIB8_9BACL/7-80 AC A0A8J2YIB8.1
#=GS A0A428J8Z8_9BACI/7-80 AC A0A428J8Z8.1
#=GS A0A268DZJ7_9BACI/7-80 AC A0A268DZJ7.1
#=GS A0A844LS73_9BACI/7-73 AC A0A844LS73.1
#=GS A0A6M0Q8I1_9BACI/7-80 AC A0A6M0Q8I1.1
#=GS A0A4Q4IGW3_9BACL/2-57 AC A0A4Q4IGW3.1
#=GS A0A495A578_9BACI/7-73 AC A0A495A578.1
#=GS A0A498D6L7_9BACI/8-76 AC A0A498D6L7.1
#=GS A0A2C1KRH8_9BACI/7-80 AC A0A2C1KRH8.1
#=GS A0A1H0ZH62_9BACI/7-80 AC A0A1H0ZH62.1
#=GS A0A8J3ENS6_9BACL/7-80 AC A0A8J3ENS6.1
#=GS A0A1L3MNG6_9BACI/7-80 AC A0A1L3MNG6.1
#=GS A0A1G8I958_9BACI/10-83 AC A0A1G8I958.1
#=GS A0A176J338_9BACI/7-80 AC A0A176J338.1
#=GS A0A371SBP4_9BACI/7-80 AC A0A371SBP4.1
#=GS A0A4S4C0H0_9BACI/7-80 AC A0A4S4C0H0.1
#=GS A0A1I1RZX4_9BACI/7-73 AC A0A1I1RZX4.1
#=GS A0A417YA50_9BACI/7-73 AC A0A417YA50.1
#=GS A0A8J8KAS2_9BACI/7-80 AC A0A8J8KAS2.1
#=GS A0A1G8XC77_9BACI/7-73 AC A0A1G8XC77.1
#=GS A0A179SZ14_9BACI/7-80 AC A0A179SZ14.1
#=GS A0A0M4FKD4_9BACI/7-80 AC A0A0M4FKD4.1
#=GS A0A6G1X4E7_9BACI/7-73 AC A0A6G1X4E7.1
#=GS A0A5R9FGA1_9BACI/24-97 AC A0A5R9FGA1.1
#=GS MSTX_BACSU/33-106 AC Q5BU39.1
#=GS A0A841PXE0_9BACI/7-73 AC A0A841PXE0.1
#=GS A0A0V8JAD3_9BACI/7-80 AC A0A0V8JAD3.1
#=GS A0A1M5IHN8_9BACI/7-73 AC A0A1M5IHN8.1
#=GS A0A417YPY1_9BACI/11-64 AC A0A417YPY1.1
#=GS A0A024Q969_9BACI/2-68 AC A0A024Q969.1
#=GS A0A6N8FJQ9_9BACI/7-73 AC A0A6N8FJQ9.1
#=GS A0A4R2P4Q6_9BACL/29-95 AC A0A4R2P4Q6.1
#=GS W9AE99_9BACI/7-80 AC W9AE99.1
#=GS A0A084GLW3_METID/7-80 AC A0A084GLW3.1
#=GS A0A4Y9A9E0_9BACI/7-73 AC A0A4Y9A9E0.1
#=GS A0A1I0W512_9BACI/32-98 AC A0A1I0W512.1
A0A428N453_9BACI/43-116 ......df--NKYSEAIDKIQEGNESMIELFNELEDDDPLINFGQDVIDDIGKAKEKFGDETVDKKINTVVREMLSWLNLN-e....
A0A161WD43_9BACI/7-80 ........EKKQLSTAIDNMNDALDVFIELYNESEEDVSIIEFEDQTIKAIKRAVDAYGKEAVSKKINTIITEIFSFLAET-k....
A0A4R6U6N2_9BACI/7-80 ........EQVQLSKAIDSLNVGLDALIVLYNESDDEQLFFEPSEALIATYNKVTSTLDPTVVNDRLDRLMIAMLEA-----mmptk
A0A0K0GC12_9FIRM/7-73 ........ESKRFDKALDE-------ILDLFNNLESDEPIIKYNDEVLSFIEKAKKKYGEDIVNEKVNIVVGEMLSWLDLED.....
A0A3A1QWN8_9BACI/9-82 ........ERNQLSQAIDQLSEGLDAFIELYNESVEDKPLLQLTEENEGLLGKAIIKFGGNEVNEKVNKVIAELLEWLPLDD.....
A0A0L0QMH0_VIRPA/7-73 .......e-SKQFDKALDT-------FIELYNNLEPDVPLIQFTDDVVEQIEAAKQAYGEEVIHEKINSIVREALSWTTLT-k....
A0A1B1Z7B0_9BACI/1-63 ........-----------MQEGLDSMIDLYNEAEDDEDLIQYEEEVISAIKRAKETFGNDFIDQKINTIVKEVLSLMQ---ggq..
A0A1H0WYF5_9BACI/7-80 ........EKKTLSSAIDKLNEGLDEIIALYNEAEEDRPFIQFEPVVMESIEKAKETFGEEEISRRINTIIKEVFSFLPTT-e....
I8AJB9_9BACI/7-80 .......s-KQLYSKAIDSMQEGLEAMIDLYNEAEEDRMLIQFDEDVEEKIVNAKELHGSDFINRKINAIIREVLTLTKNED.....
A0A1I0CD54_9BACI/7-73 .....erk---KFDN-------ALDDILDLFNNLEDDEPIIKFADDVMENIEFAKKKYGDETVDEKINTLVREMLSWLDLED.....
A0A223KUB7_9BACI/7-80 ........EKTTLSNAIDQMNESLDKFIELYNEAEEDKEIITFDEEVVKLIQTGMDTYGEEAITKKINTIVKEVLSLITEQ-e....
A0A235F4E4_9BACI/7-80 ........DRQAYSDAIDKMQEGLDAMIDLYNEAEEDVDLIQFDEDLIELIKKAKKKHGEQLINKKVAAIVREVIELLTME-n....
A0A7X2J0I9_9BACI/7-80 ........EKSSLSEAIDRMNEGLDAFIQYYNESEEDKPLIEFSEETQSAIHAAVSSYGKEEVEKRINNIIKEIFSFLPP--hq...
A0A263BS01_9BACI/7-80 ........ENKELSKAIDQITEGLDTVIELYNESELDEPILSWSEENISKIKRANEHYGIEVVQTKINKIVSEMLDWLPLE-e....
A0A6N8CLJ7_9BACI/2-73 .kandqer---------DKFDKALDTIINLFNELEDDEPIVEFDPDVIQKIEIAKKIYGANVINERINNVVKEILTLLPLD-a....
A0A549YJB8_9BACI/7-73 ......et--KRFDKALDE-------ILDLYNNLEEDEPVIQFETDVMEMIERAKVKYGNDMVNEKINTVVRAMLSWLDLDD.....
A0A3R9P774_9BACI/16-89 ......df--NKYSEAIDKIQEGNESMIELFNELEDDDPLINFGQDVVENVGKAKEKFGDETIDEKINTVVREMLSWLQLND.....
A0A1J6WA39_9BACI/7-80 .......e-IEKYSDAIDKMQEGLEAMIELYNDMEEDTPFIDLEDGVLEDLEKAKRIYGEEYVSKKVNTILKEVLTWLDLD-e....
A6CLW8_9BACI/7-80 ........ERSQLSQAIDQLSEGLDTIIELYNNSVEDKPLLQLTDENEELLSRATIKYGGEEVNGKVNKVIAELLEWLPLDD.....
A0A0N0VNH2_9BACI/14-87 ........EKEQLSEAIDQMNESLDRFIEFYNESEEDKPIISFNDEVIQLIEAGKQKYGEEALNQKINSIVKEVLSFISSG-d....
A0A7H8S4L3_9BACI/7-73 ......et--KRFDKALDE-------ILDLFNNLEEDKPVIQFDAEVLENIERAKIKYGSDMVDEKINTVVHEMLSWLDLD-e....
A0A1I0JIG5_9BACI/7-73 ........EQKRFDKALDE-------IIDLFNNIESDVPIIQYSDKVVENIEKAKKKYGEEVMNERVNNVVGEMLSWLDLDD.....
A0A8J2YIB8_9BACL/7-80 ........ESQLFSDAIDAINNGMEDIINLYNALEEEQQLIQFEESVVAHIEKAKAKYGEAFVDQKINTVIKEMLDWLPLDD.....
A0A428J8Z8_9BACI/7-80 ........EKQALSDAIDKMNEGLDAFIGLYNESEEDKQLIVYDDDVTEIIQKAINRYGEDKIAKKINSIIREVLSLLASD-e....
A0A268DZJ7_9BACI/7-80 ........EKKLLSEAIDKMNEGLDTFIGFYNDSEEDKPLIEFTDETIETIQRAIDVYGKDEVTTKINTIIREILSFLPNN-k....
A0A844LS73_9BACI/7-73 ......et--KRFDKALDE-------FIELFNNLEKDEPIIHFEEEVVQNIERAKKKYGNDMVDEKINTVVREMLSWLDLED.....
A0A6M0Q8I1_9BACI/7-80 ........EKTSLSDSIDKLNEGLDTIIQLYNEAEEDKSLIDFDDDTIHIIQSAKKAYGEKEIDERINKIIKEILSLLPLD-q....
A0A4Q4IGW3_9BACL/2-57 vqfaetka--------------------------INDQLVIRFGQDVIEYVRKAQQIYGEDVVNQRINNVVREILLLLPL--pe...
A0A495A578_9BACI/7-73 ........ESKRFDKALDE-------ILDLFNNLESDEPIIQYSEEVLKYIELAKKKYGDDLVNEKVNTVVGEMLSWLDLD-e....
A0A498D6L7_9BACI/8-76 .....eee-SKRFDKALDE-------FIDLFNNLESDVPVVQFTEEVLEKIEKAMEQYGVEVIEERINKVVEELLSWLELN-e....
A0A2C1KRH8_9BACI/7-80 ........EKKLLSEAIDKMNEGLDSFIGFYNDSEEDKALIEFSEDTIETIEKAIDTYGKDEVTTKINTIIKEVLSFIPNKK.....
A0A1H0ZH62_9BACI/7-80 .......d-YQKYSDAIDQIQQGNDAMIDLFNEMEDDTELIGFDQNVVNQIEKAKIKFGDDAVNEKINTVVREMLSWLDLE-g....
A0A8J3ENS6_9BACL/7-80 ........ESQIFSDAIDAINNGMEDIINIYNTLEEDQPLIQFDDAVVQQIEKVKQKYGNEFVDKKINTVVKEMLDWLPLED.....
A0A1L3MNG6_9BACI/7-80 ........EKKALSEAIDRMNEGLDAFIELYNESEDDSELIEFQEETIQVIEKAIQAYGKEIVTNKINTIVKEVLSFLPAK-k....
A0A1G8I958_9BACI/10-83 .......d-YHKYSEAIDKIQEGNNAMIELFNELEDDDPLIHFGEDVMENIEKAKKKFGDDVVDEKINTVVREMLSWLDLND.....
A0A176J338_9BACI/7-80 ........EKENLSEAIDQMNEALDVFIQIYNQSEEDKPILRFTAETEKIILKAIEIYGEKTIEHKINTLIKEFLSFTDSK-t....
A0A371SBP4_9BACI/7-80 ........EKKVLSDSIDKLNEGLDVVIQLYNEAEEDKPIIQFDDEVIDAIEKAKQTFGDEEITRRINTIIKEIFAFLPKD-e....
A0A4S4C0H0_9BACI/7-80 ........EKKQLSEAIDKMNEGLDAFIGFYNDSEEDKALIEFSDETIETIQLAIETYGKEEVTTKINTIIKEVLSFLPNKK.....
A0A1I1RZX4_9BACI/7-73 ......et--KRFDKALDE-------ILDLFNNLEDDKPVINFNTEVLQNIERAKRKYGSGMVDEKINTVVHEMLSWLDLED.....
A0A417YA50_9BACI/7-73 ......et--KRFDKALDE-------ILDLFNNLENDEPIIDFNDDVLELIEKAKKKYGIEQVSGKINTIVEEMLSWLDLND.....
A0A8J8KAS2_9BACI/7-80 ........ENKKLSDAIDQMQSALDVFIEMYNDSEEDKLHIQLDADVIELIEKAKNVYGSEVVNEKVNTIIKEVLTFLPLEN.....
A0A1G8XC77_9BACI/7-73 ........ESKKFDKALDE-------ILDLFNNLESDDPIIHFGQDVMDNIERAKKKYGNDMVDEKINTVVREMLSWLDLD-e....
A0A179SZ14_9BACI/7-80 ........EKKLLSEAIDKMNEGLDAFIGFYNDSEEDKALIEFSEETIEIIEHAIDTYGKEEVTTKINTIIREVLSFLPNKK.....
A0A0M4FKD4_9BACI/7-80 ........EQNLLSGAIDKMNEGLDAFIQLYNEAKIQKNNIEFDEDTLKVIEEAIEVHGKETIEKKLNRIVQEILSFSVT--gn...
A0A6G1X4E7_9BACI/7-73 ........ERKRFDKALDE-------IIDLFNNLESDVPIIQYSDEVLENIERAKKKYGEDMMNERINKVVGEMLSWLDLDD.....
A0A5R9FGA1_9BACI/24-97 ........ENKKLSDIIDQLTDGLDSLVEIYNDSEEDVPLIAFKPNVVESIEKAKKVYGAKHVDDKINKIVQETLSWLPLD-e....
MSTX_BACSU/33-106 ........EKEQLSTAIDRMNEGLDAFIQLYNESEIDEPLIQLDDDTAELMKQARDMYGQEKLNEKLNTIIKQILSISVSE-e....
A0A841PXE0_9BACI/7-73 .......e-SKRFDKALDE-------FIDLFNNLETDEPVIGFGDDVLENIKRAKKKYGNDMVDEKINTVVREMLSWLELDD.....
A0A0V8JAD3_9BACI/7-80 .......s-KKLYSDAIDRMQEGLEAMIDLYNEAEDDIPLINFEKEVQEEIEKAKSKYGSAFIDDKINAIVKEVLSFLPPD-q....
A0A1M5IHN8_9BACI/7-73 ........EKKKFDKALDD-------ILELFNNLEEDEPIIKFTDDVFENIELAKKKYGDETVDEKINTVVREMLSWLDLD-e....
A0A417YPY1_9BACI/11-64 ......et--KRFDKALDE-------ILDIFNNIEDDEPIINFNVEVLELIEKAKKKYGIEKVSEKI---------------sm...
A0A024Q969_9BACI/2-68 .......e-SKRFDKALDE-------FIDLFNNLETDVPIIQFGEDVIKNIELAKQKYGEAVIDKKINIVVREMLSLLDLEN.....
A0A6N8FJQ9_9BACI/7-73 ........ERKKFDKALDD-------ILDLFNNLEDDVPIINFNEEVIENIELAKKKYGDDTIDEKINALVREMLSWLDLED.....
A0A4R2P4Q6_9BACL/29-95 ...enkdf------------SNALDTIIELFNNLEDDEPLIEFGQDVIEDIERAKKMYGQNIINERINNVVREILSLLTLD-e....
W9AE99_9BACI/7-80 .......d-YQKYSDAIDRIQEGNEAMIELFNELEKDNPVIDLNEELLKNITRAKEKYGEEVIDQKINSIIAEMLSWLDLN-e....
A0A084GLW3_METID/7-80 ........EKTALSEAIDKMNEGLDVFIQFYNDAEEEKPVIEFKEDTIAAIEKAIEAYGTETVSEKINAIIREVLSFLPNKK.....
A0A4Y9A9E0_9BACI/7-73 ......et--KRFDKALDE-------ILDLFNNLEEDKPVIQFDTGVLENIERAKRKYGSDIVDEKINTVVHEMLSWLDLDD.....
A0A1I0W512_9BACI/32-98 ......et--KRFDKALDE-------ILDLFNNLEEDKPVIQFDADVLENIERAKIKYGSDMVDEKINTVVHEMLSWLDLED.....
#=GC seq_cons .........pcphscAlDchppu.-shI-LaNphE-DcPlIpFs--Vl-tIE+AKcpYGp-hVscKINolV+EhLSaLsLc......
//
