#=GF ID Mso1_C
#=GF AC PF14477.10
#=GF DE Membrane-polarising domain of Mso1
#=GF AU Coggill P;0000-0001-5731-1588
#=GF SE PF14475
#=GF GA 23.20 23.20;
#=GF TC 23.20 26.00;
#=GF NC 21.80 22.00;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP Domain
#=GF RN [1]
#=GF RM 9207091
#=GF RT Mso1p: a yeast protein that functions in secretion and interacts
#=GF RT physically and genetically with Sec1p.
#=GF RA Aalto MK, Jantti J, Ostling J, Keranen S, Ronne H;
#=GF RL Proc Natl Acad Sci U S A. 1997;94:7331-7336.
#=GF RN [2]
#=GF RM 16006618
#=GF RT A gene truncation strategy generating N- and C-terminal deletion
#=GF RT variants of proteins for functional studies: mapping of the
#=GF RT Sec1p binding domain in yeast Mso1p by a Mu in vitro
#=GF RT transposition-based approach.
#=GF RA Poussu E, Jantti J, Savilahti H;
#=GF RL Nucleic Acids Res. 2005;33:e104.
#=GF RN [3]
#=GF RM 20181830
#=GF RT Mso1p regulates membrane fusion through interactions with the
#=GF RT putative N-peptide-binding area in Sec1p domain 1.
#=GF RA Weber M, Chernov K, Turakainen H, Wohlfahrt G, Pajunen M,
#=GF RA Savilahti H, Jantti J;
#=GF RL Mol Biol Cell. 2010;21:1362-1374.
#=GF RN [4]
#=GF RM 21119007
#=GF RT Sec1p and Mso1p C-terminal tails cooperate with the SNAREs and
#=GF RT Sec4p in polarized exocytosis.
#=GF RA Weber-Boyvat M, Aro N, Chernov KG, Nyman T, Jantti J;
#=GF RL Mol Biol Cell. 2011;22:230-244.
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC Mso1p is a component of the secretory vesicle docking complex
#=GF CC whose function is closely associated with that of Sec1p. It is a
#=GF CC small hydrophilic protein that is enriched in the microsomal
#=GF CC membrane fraction [1]. The yeast Sec1p protein functions in the
#=GF CC docking of secretory transport vesicles to the plasma membrane
#=GF CC [2]. Mso1p and Sec1p interact at sites of exocytosis and the
#=GF CC Mso1p-Sec1p interaction site depends on a functional Rab GTPase
#=GF CC Sec4p and its GEF Sec2p [3]. This C-terminal region of Mso1
#=GF CC assists in targeting Sec1 to the sites of polarised membrane
#=GF CC transport, the SNARES and Sec4 [4].
#=GF SQ 22
#=GS Q5A3M2_CANAL/125-169 AC Q5A3M2.1
#=GS M3K471_CANMX/130-186 AC M3K471.1
#=GS Q6FWR7_CANGA/142-194 AC Q6FWR7.1
#=GS G3BEK6_CANTC/122-182 AC G3BEK6.1
#=GS Q6BLU3_DEBHA/141-211 AC Q6BLU3.1
#=GS C5MBJ3_CANTT/119-172 AC C5MBJ3.1
#=GS A5DTK6_LODEL/152-202 AC A5DTK6.1
#=GS A0A1E4RRS8_9ASCO/132-194 AC A0A1E4RRS8.1
#=GS G8BCX5_CANPC/112-179 AC G8BCX5.1
#=GS A0A1E4SDB4_9ASCO/150-213 AC A0A1E4SDB4.1
#=GS A0A8J5UJ11_9ASCO/127-194 AC A0A8J5UJ11.1
#=GS A0A367YC34_9ASCO/130-183 AC A0A367YC34.1
#=GS A0A1A0HEM0_9ASCO/116-191 AC A0A1A0HEM0.1
#=GS A0A1L0BAH8_9ASCO/69-189 AC A0A1L0BAH8.1
#=GS A0A421JE04_9ASCO/126-190 AC A0A421JE04.1
#=GS G3ATI9_SPAPN/128-169 AC G3ATI9.1
#=GS A0A642UJN0_DIURU/147-202 AC A0A642UJN0.1
#=GS A0A8H6F3L9_CANAX/125-169 AC A0A8H6F3L9.1
#=GS G8Y7I0_PICSO/147-210 AC G8Y7I0.1
#=GS A5DEZ4_PICGU/127-193 AC A5DEZ4.2
#=GS A0A367YDV6_9ASCO/123-177 AC A0A367YDV6.1
#=GS YAM5_SCHPO/92-142 AC Q10060.1
Q5A3M2_CANAL/125-169 ...............................................................ngsdrpnsggyq---.......------..............RSSSRLQDLYNKSRQQS..IPGQGYNT-S......NS-.--.-------------wshnr..
M3K471_CANMX/130-186 ...............................................................qqtpppqqgspq---.......-----QgeisterpssggyqRSSSRLQDLYNKSRQQS..IPGQGYQT-S......N--.--.-------------srg....
Q6FWR7_CANGA/142-194 ...........................................................................LSS.......MASPSV..............RSPLRARSTWSSEADSA.kISSAGTNS--......TAE.SN.NGSAMDPQNMMRA.......
G3BEK6_CANTC/122-182 ..........................................................................q-SQ.......YAEPAPaaqs......aykpRSSSRLQDMYNKSRQQH..VPGGGYNTVNq....aPAR.TN.SST---SGARLRE.......
Q6BLU3_DEBHA/141-211 .......................................................................asqnTSQhapqhvpEAEPQRpt.........ytpRSSSRLQDMYNKSRQQS..IPGSGYNTQSyp..sgPLR.TN.SST---TGSRLRE.......
C5MBJ3_CANTT/119-172 ................................................................qqqqqqqqetp---.......--SPERpsa........gyqRSSSRLQDLYNKSRQQT..VPGQGYRTAN......TWN.SN.-------------r......
A5DTK6_LODEL/152-202 .............................................................aqstqpqsdlsrgs-SR.......SSAPSV.............qRSSSRLQDMYNKSRQQS..A-TSGYSS--......---.--.-------------arys...
A0A1E4RRS8_9ASCO/132-194 ................................................................esqggaevgrk---.......QSSYTP..............RSSSKLFDLYNKSRQQA..VPGSGYNAQSa...paPAR.SN.TSG--AHSSRLRE.......
G8BCX5_CANPC/112-179 .........................................pvrqdnlfnksysqrsynqqqrmqdendagqgqt---.......--PPPF.............qRSSSKLQEMYNKSRQQS..TPGSGYN---......---.--.-------------fsrys..
A0A1E4SDB4_9ASCO/150-213 ................................................................qaqaqaqaqep---.......----AKpty........qsrASSSRLLDMHNRSKQQA..VPGQGYNSQPy....qPNR.SN.STS--VSGNRLRE.......
A0A8J5UJ11_9ASCO/127-194 ..............................................................qqerpasnttttn---.......--TPGY..............RSQSKLQDMYNKSRQQPtpAASATYAPKSdtahpqPIR.TN.SYS--VTGNRLRE.......
A0A367YC34_9ASCO/130-183 .................................................................qqvqqqqdtp---.......--SPERpst.......ggyqRSSSRLQDLYNKSRQQS..IPGQGYRT-S......---.--.-------------ntyhpnr
A0A1A0HEM0_9ASCO/116-191 .......................................................tsafsapasreasvpdsepd---.......-----Erp.........yarRTNSRLQQMYNKTRQNS..LPGSGYSSLSpa..pqPALiSA.GSRGNSSGQRLRD.......
A0A1L0BAH8_9ASCO/69-189 svparsaarqaqtaagnystfqptsgsqatsalaqyqpvrasynssnsastyqpqqthsrqnsnadsadeergyt---.......-----R..............RSNSRLQEMYNKSRQQG..IPGAGYNAQQa....qPST.SRqNLT----------aslrlrd
A0A421JE04_9ASCO/126-190 ........................................................................sqgRSQhq...etQSAPARt...........ytRSSSRLQDMYNRSREQS..VPGAGYSSSSy....qPAR.TN.SAS-GGSSSRLRD.......
G3ATI9_SPAPN/128-169 ....................................................................ytertps---.......---PNEtt..........syRSSSRLQDMYNKSRQQS..LPGSTYKQ--......T--.--.-------------aa.....
A0A642UJN0_DIURU/147-202 .......................................................................adst---.......-PSPERpg..........ysRGASRLDNLYNKSRMQS..VPGQGYNM--......GHN.QR.PTTHSATGSRLRE.......
A0A8H6F3L9_CANAX/125-169 ...............................................................ngsdrpnsggyq---.......------..............RSSSRLQDLYNKSRQQS..IPGQGYNT-S......NS-.--.-------------wshnr..
G8Y7I0_PICSO/147-210 .....................................................................aneape---.......EAYPQRpt.........yipRKSSRLQDMYNRSRQQA..IPGSGYNSQIh....qPAP.TR.SNSSSTTGSRLRE.......
A5DEZ4_PICGU/127-193 .......................................................................wsqdRSQhq...etQSAPARt...........ytRSSSRLQDMYNRSREQS..VPGAGYSSQSy....qPAR.TN.SASGNGSSSRLRD.......
A0A367YDV6_9ASCO/123-177 ................................................................qqvqqrqqdtp---.......--SPERpgt.......ggyqRSSSRLQDLYNKSRQQS..IPGQGYRT-S......---.--.-------------ntyhpnr
YAM5_SCHPO/92-142 ...........................................................................TSS.......ASSPPL..............R---RLPSVQHSTFDDL..FEGVGSLQKS......PST.TK.PLSSTPSGSLLRS.......
#=GC seq_cons .....................................................................ttts.s.............Pth..............RSSSRLQDhYNKSRQQo..lPGsGYso.s......s...pt.....................
//
