#=GF ID MtrA
#=GF AC PF04208.18
#=GF DE Tetrahydromethanopterin S-methyltransferase, subunit A
#=GF AU TIGRFAMs;
#=GF AU Finn RD;0000-0001-8626-2148
#=GF SE TIGRFAMs (release 2.0);
#=GF GA 25.00 25.00;
#=GF TC 26.50 30.80;
#=GF NC 24.40 23.10;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 9559648
#=GF RT Cloning, sequencing and expression of the genes encoding the
#=GF RT sodium translocating N5-methyltetrahydromethanopterin : coenzyme
#=GF RT M methyltransferase of the methylotrophic archaeon
#=GF RT Methanosarcina mazei Go1.
#=GF RA Lienard T, Gottschalk G;
#=GF RL FEBS Lett 1998;425:204-208.
#=GF DR INTERPRO; IPR030688;
#=GF DR TC; 3.C.1;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC The N5-methyltetrahydromethanopterin: coenzyme M (EC:2.1.1.86)
#=GF CC of Methanosarcina mazei Go1 is a membrane-associated,
#=GF CC corrinoid-containing protein that uses a transmethylation
#=GF CC reaction to drive an energy-conserving sodium ion pump [1].
#=GF SQ 151
#=GS A0A5B2YV02_9ARCH/25-161 AC A0A5B2YV02.1
#=GS A0A2V2MU24_9EURY/4-175 AC A0A2V2MU24.1
#=GS E3GZ46_METFV/4-175 AC E3GZ46.1
#=GS A0A366M815_9EURY/4-176 AC A0A366M815.1
#=GS Q6LWY9_METMP/4-178 AC Q6LWY9.1
#=GS A0A0P1MT82_9BACT/100-274 AC A0A0P1MT82.1
#=GS A0A557SZL1_9ARCH/35-171 AC A0A557SZL1.1
#=GS E1RDW9_METP4/4-175 AC E1RDW9.1
#=GS A0A2V3JJU5_9EURY/1-165 AC A0A2V3JJU5.1
#=GS A0A2U1S6W4_9EURY/4-174 AC A0A2U1S6W4.1
#=GS F4C0Q4_METSG/15-179 AC F4C0Q4.1
#=GS A0A315Y8R4_9EURY/4-173 AC A0A315Y8R4.1
#=GS MTXA_METMA/1-142 AC Q8Q082.1
#=GS F0T8R8_METLA/4-176 AC F0T8R8.1
#=GS A0A328SS47_9EURY/4-176 AC A0A328SS47.1
#=GS MTRA2_METTH/7-180 AC O27134.1
#=GS A0A521EFL4_9BACT/35-188 AC A0A521EFL4.1
#=GS L0HHV5_METFS/4-176 AC L0HHV5.1
#=GS A0A060HGZ4_9ARCH/21-158 AC A0A060HGZ4.1
#=GS Q8PUT0_METMA/1-164 AC Q8PUT0.1
#=GS MTRA_METKA/4-181 AC O32867.3
#=GS W9DNG2_METTI/4-176 AC W9DNG2.1
#=GS MTRA_METHJ/4-175 AC Q2FRN2.1
#=GS A0A062VAV6_9EURY/2-170 AC A0A062VAV6.1
#=GS F6BEA3_METIK/4-178 AC F6BEA3.1
#=GS Q0W334_METAR/4-176 AC Q0W334.1
#=GS A0A8J7W6N0_9FIRM/120-294 AC A0A8J7W6N0.1
#=GS MTRA_METST/4-176 AC Q2NI29.1
#=GS A0A2K5AP80_9ARCH/17-164 AC A0A2K5AP80.1
#=GS A0A4P2VAP3_9ARCH/1-151 AC A0A4P2VAP3.1
#=GS A6UWH8_META3/4-177 AC A6UWH8.1
#=GS A0A8J7RFC5_9EURY/4-176 AC A0A8J7RFC5.1
#=GS F4BZJ2_METSG/4-176 AC F4BZJ2.1
#=GS B8GF36_METPE/3-173 AC B8GF36.1
#=GS V6AVU3_9ARCH/12-154 AC V6AVU3.1
#=GS A0A2H1EFQ4_9ARCH/15-162 AC A0A2H1EFQ4.1
#=GS A0A1X0Q8T9_9MICR/1-161 AC A0A1X0Q8T9.1
#=GS D5E9T3_METMS/2-157 AC D5E9T3.1
#=GS F7XQ94_METZD/4-175 AC F7XQ94.1
#=GS A0A2H5X395_9BACT/106-267 AC A0A2H5X395.1
#=GS A0A7X8N8W7_9FLAO/38-208 AC A0A7X8N8W7.1
#=GS G7WPT7_METH6/4-176 AC G7WPT7.1
#=GS A0A0X3BMW3_9EURY/4-175 AC A0A0X3BMW3.1
#=GS J9Z8W3_LEPFM/11-182 AC J9Z8W3.1
#=GS MTRA_METAC/4-175 AC Q8TU03.1
#=GS A0A1D3L4Q6_9EURY/4-177 AC A0A1D3L4Q6.1
#=GS A0A2H5VDH7_9ARCH/16-163 AC A0A2H5VDH7.1
#=GS C1F4T6_ACIC5/100-275 AC C1F4T6.1
#=GS A0A483CUU9_9EURY/4-175 AC A0A483CUU9.1
#=GS Q12TW9_METBU/4-135 AC Q12TW9.1
#=GS D7DUI1_METV3/4-177 AC D7DUI1.1
#=GS I0INS9_LEPFC/103-274 AC I0INS9.1
#=GS MTRA_META3/4-177 AC A6UWH7.1
#=GS MTRA_METV3/4-179 AC D7DUI0.1
#=GS U6E9X4_9EURY/3-175 AC U6E9X4.1
#=GS A0A1F2P5I4_9EURY/11-203 AC A0A1F2P5I4.1
#=GS F6BEA2_METIK/4-179 AC F6BEA2.1
#=GS K0IN48_NITGG/13-157 AC K0IN48.1
#=GS A0A2Z4L910_9EURY/4-177 AC A0A2Z4L910.1
#=GS A0B8Y2_METTP/4-176 AC A0B8Y2.1
#=GS A0A2V3JFY1_9EURY/3-175 AC A0A2V3JFY1.1
#=GS A0A7R6WCH7_9GAMM/115-292 AC A0A7R6WCH7.1
#=GS Q0W333_METAR/4-176 AC Q0W333.1
#=GS A0A2H5XER2_9BACT/106-274 AC A0A2H5XER2.1
#=GS A0A8J7UPH3_9EURY/4-175 AC A0A8J7UPH3.1
#=GS A0A8K0Y3E9_9ARCH/16-157 AC A0A8K0Y3E9.1
#=GS MTXA_METAC/1-167 AC Q8TPU9.1
#=GS S2E6G3_9ARCH/10-150 AC S2E6G3.1
#=GS A0A484F5X7_9EURY/6-177 AC A0A484F5X7.1
#=GS A0A1G5S0A0_9FIRM/4-149 AC A0A1G5S0A0.1
#=GS A0A1D2W9U9_9EURY/4-176 AC A0A1D2W9U9.1
#=GS A0A4E0QC44_9EURY/1-44 AC A0A4E0QC44.1
#=GS A0A1B4V6T0_9GAMM/19-179 AC A0A1B4V6T0.1
#=GS A0A1V6N4F9_METAZ/4-176 AC A0A1V6N4F9.1
#=GS A0A062V305_9EURY/4-175 AC A0A062V305.1
#=GS I7J9J6_METBM/4-175 AC I7J9J6.1
#=GS A7I5S6_METB6/4-176 AC A7I5S6.1
#=GS A0A1D2WB62_9EURY/4-175 AC A0A1D2WB62.1
#=GS A0A166CFB8_9EURY/4-176 AC A0A166CFB8.1
#=GS A0A0E3P281_9EURY/4-175 AC A0A0E3P281.1
#=GS H1YXH2_9EURY/4-175 AC H1YXH2.1
#=GS A0A0E3L195_9EURY/1-166 AC A0A0E3L195.1
#=GS A0A3B0B3Q5_9ACTN/2-156 AC A0A3B0B3Q5.1
#=GS A0A1D2W6E8_9EURY/4-175 AC A0A1D2W6E8.1
#=GS D7E9H2_METEZ/4-170 AC D7E9H2.1
#=GS A0A562JHZ4_9FIRM/3-161 AC A0A562JHZ4.1
#=GS A0A1F2P9Q7_9EURY/5-197 AC A0A1F2P9Q7.1
#=GS MTRA1_METRM/4-176 AC D3E045.1
#=GS A0A2V3JCJ5_9EURY/4-180 AC A0A2V3JCJ5.1
#=GS D5E6K1_METMS/61-197 AC D5E6K1.1
#=GS A0A484IFT6_9ARCH/24-163 AC A0A484IFT6.1
#=GS L0HFU1_METFS/4-175 AC L0HFU1.1
#=GS MTRA2_METRM/4-176 AC D3E0P6.1
#=GS A0A4E0Q7M2_9EURY/4-175 AC A0A4E0Q7M2.1
#=GS D5E6K1_METMS/5-52 AC D5E6K1.1
#=GS D1YVZ3_METPS/4-174 AC D1YVZ3.1
#=GS E3GWY7_METFV/4-167 AC E3GWY7.1
#=GS A0A166F2M3_9EURY/4-176 AC A0A166F2M3.1
#=GS A0A0E3NXE8_9EURY/1-163 AC A0A0E3NXE8.1
#=GS A9A2W6_NITMS/13-155 AC A9A2W6.1
#=GS A0A0X3BPL6_9EURY/1-82 AC A0A0X3BPL6.1
#=GS A7I5S4_METB6/4-175 AC A7I5S4.1
#=GS I7KDB4_METBM/4-175 AC I7KDB4.1
#=GS A0A7J0CEE5_9ACTN/2-143 AC A0A7J0CEE5.1
#=GS B8GE98_METPE/4-175 AC B8GE98.1
#=GS MTRA_METEZ/4-176 AC D7EBK7.1
#=GS A0A8J7WAV0_9EURY/4-176 AC A0A8J7WAV0.1
#=GS A0A447G1P4_9ARCH/20-161 AC A0A447G1P4.1
#=GS B8GEA0_METPE/4-175 AC B8GEA0.1
#=GS A2STR2_METLZ/4-175 AC A2STR2.1
#=GS Q2FRN1_METHJ/4-175 AC Q2FRN1.1
#=GS G7WNE2_METH6/27-186 AC G7WNE2.1
#=GS A0A6A8FKD1_9ARCH/20-165 AC A0A6A8FKD1.1
#=GS Q12VU8_METBU/4-176 AC Q12VU8.1
#=GS A0A166A6Y5_9EURY/4-176 AC A0A166A6Y5.1
#=GS A0A1Q8QRX9_9FIRM/120-288 AC A0A1Q8QRX9.1
#=GS L0L1I6_METHD/4-175 AC L0L1I6.1
#=GS A0A1D3L1Z6_9EURY/4-174 AC A0A1D3L1Z6.1
#=GS A0RXI7_CENSY/1-140 AC A0RXI7.1
#=GS A0A2U3QE55_9BACT/3-178 AC A0A2U3QE55.1
#=GS Q2W818_MAGSA/105-263 AC Q2W818.1
#=GS A0A4E0QC44_9EURY/53-191 AC A0A4E0QC44.1
#=GS M7TUS0_9ARCH/5-170 AC M7TUS0.1
#=GS MTRA_METMS/4-176 AC D5E7Y7.1
#=GS A0A0X3BN73_9EURY/4-112 AC A0A0X3BN73.1
#=GS A0A0S2TEW1_9GAMM/98-273 AC A0A0S2TEW1.1
#=GS A0A498GZI2_9EURY/4-175 AC A0A498GZI2.1
#=GS A0A0J1FHJ2_9FIRM/118-282 AC A0A0J1FHJ2.1
#=GS A0A1A9I7U7_9BACT/41-198 AC A0A1A9I7U7.1
#=GS A0A498GYL0_9EURY/4-175 AC A0A498GYL0.1
#=GS A0A483CVS8_9EURY/4-175 AC A0A483CVS8.1
#=GS A0A8J7W6P9_9EURY/4-175 AC A0A8J7W6P9.1
#=GS A2STR4_METLZ/4-175 AC A2STR4.1
#=GS L0KYT2_METHD/8-174 AC L0KYT2.1
#=GS E1RDW7_METP4/4-175 AC E1RDW7.1
#=GS A0A315XLQ9_9EURY/4-175 AC A0A315XLQ9.1
#=GS F7XKL5_METZD/1-167 AC F7XKL5.1
#=GS A0A328S3T3_9EURY/4-177 AC A0A328S3T3.1
#=GS A0A8J7NAQ9_9ARCH/1-162 AC A0A8J7NAQ9.1
#=GS MTRA_METMP/4-178 AC Q6LWZ0.1
#=GS MTRA_METJA/4-179 AC Q58261.2
#=GS A0A2V2N3V7_9EURY/4-175 AC A0A2V2N3V7.1
#=GS R9SLV8_9EURY/4-176 AC R9SLV8.1
#=GS U6EEN6_9EURY/4-177 AC U6EEN6.1
#=GS MTRA_METMA/4-175 AC O59640.2
#=GS H1YXH4_9EURY/4-175 AC H1YXH4.1
#=GS D1YWC8_METPS/5-159 AC D1YWC8.1
#=GS A0A6A7LBE6_9ARCH/52-196 AC A0A6A7LBE6.1
#=GS A0A328PA09_9EURY/4-177 AC A0A328PA09.1
#=GS MTRA1_METTH/4-176 AC O27227.3
#=GS A0A1D2WAN0_9EURY/4-174 AC A0A1D2WAN0.1
A0A5B2YV02_9ARCH/25-161 ...................sfsgkg--------------.---..----KTVAVCTL........S.S........L.D...LL...Q....A.....IskdeIM...N...K......ILIVGRLYSENKGIDDLINY.CTNSSTLKYLVLCGQDTR...GHYSGDALIKLGLYGV...dS....V....GR.IINTKAPRPYLT-LKPEVIEKFRSDI.QIIDMRE....VCKLEEIKLRIDDL---...........----------------------g........................
A0A2V2MU24_9EURY/4-175 ........................k-GDAASGWPIVQGD.FHT..GDVKSPVAVITM........G.S........H.L...DE...Q....A.....I....CN...A...G......AAIAGSCKTENLGLEKVIAN.VISNPNIRFVLTCGTEVK...GHLSGQSLIALHKDGV....N....G....GK.IVGSKGAIPFIENLTADNIKRFQEQV.EIVDIME....AEDIGAISAKINELKAR...........DPGVFPGGPMVVEIKEEGG---gga......................
E3GZ46_METFV/4-175 .........................KKEPAEGWPVVSGD.YIV..GDPESPVAAVTL........A.S........H.I...ED...I....P.....I....-D...A...G......AAIAGPCKTENLGIEKVIAN.IISNPNIRFLVLCGSEVQ...GHITGQSIKALHKNGV....D....D....KKkIIGAKGAIPYIENLPEEALERFQKQV.EIVDLID....VEDADQIKEKVKECIEK...........DPGAFEEEAMVVKVEEEEEEG-e........................
A0A366M815_9EURY/4-176 .........................KKPPAEGWPIINGD.YIA..GDPESPVAVTTL........G.S........H.N...ED...V....A.....A....-N...A...G......AAIAGPCKTENLGIEKVVAN.IISNPNIRFLILCGSEVQ...GHITGQSFEALHQNGV...dP....E....KRsIMGATGAIPYVENIPDEGVERFQTQV.EVLNMID....VEDAGAIEAKVKECIEK...........DPGAFEEEAYVISLDENGEEE-d........................
Q6LWY9_METMP/4-178 .........................KKAPAAGWPVANGE.YVV..GNPESCVAVVTL........G.S........H.G...LD...Q....A.....A....ID...A...G......AAISGPCHTENLGIEKVVAN.YISNPNIRFMVITGSEVQ...GHITGQCIKALYENGI...gD....D....GG.IIGAKGAIPFMENVGTEPVGRLQSQIvECIDLID....VEDTGKISDAIKNCISK...........DPGAFEEEPMVIELEGGA----aaage....................
A0A0P1MT82_9BACT/100-274 .....................evre-----KTWPVVAGE.YFAfcDGVECPVAVSTL........A.S........V.E...LA...E....Q.....L....VK...V...Rp...keLCIVGKTETENIGIDKIIKN.TITNPTIRALLLVGKDPE...GHYSGRTILALKENGV...dE....K....MR.IIASPGKHPILKNVTREEVETFRKQV.QVIDMIG....CEDINTIVDEIRKISR-...........----------------------qviascssceftgeikstesv....
A0A557SZL1_9ARCH/35-171 ..................sfsgkgt--------------.---..-----EVAICTL........S.S........M.D...LL...K....K.....V...sSD...AimnK......LLIVGRLFSENKGIDHLIQF.CTMSSTMKYLILCGKDTN...GHYPADALMNLMQFGL...dE....H....NK.IIGTKAPYPFIKCYP-NLVNKFREQI.KLIDLRD....CYDLDKIIETVNNL---...........----------------------t........................
E1RDW9_METP4/4-175 .........................KKSPASGWPKIQGD.YHT..GDANSCVVVVTM........G.S........H.L...DE...Q....G.....V....CD...A...G......AAMCGSCKTENLGLEKIVAN.VISNPNIRFLITCGTEVK...GHLSGQCLKALHAGGV....E....G....GK.IVGAKGAIPFIENLNDAAIKRFQEQV.ELIDIME....TEDLGAIKAKVQECISK...........DPGAFEGDAMVIEVKEEEGG--ag.......................
A0A2V3JJU5_9EURY/1-165 ........................m------GWPAVSGE.FTV..GDEKNQIVLVTL........G.S........S.I...DV...T....G.....V....IN...-...K......IAIAGTMKTENIGIEKVIAN.IISNPCIRYLIICGAEVH...GHLAGDAFLAIHKSGI...dE....K....NR.IVGASGAIPFISNLSSKEVERFREQV.EIIDLVN....VEDMGQIKQAIDACAPK...........DP--FPAEPMIVTLGKVAE---adg......................
A0A2U1S6W4_9EURY/4-174 .........................KKSPAEGWPVISGD.YVV..GDPESPVAVTTL........A.S........H.I...EA...D....L.....S....--...-...G......AAIAGPCKTENLGVEKVVAN.IISNPNIRFLILSGAEVQ...GHITGQSFKALHENGC...dP....D....KKkIIGATGAIPFVENVPLDGVERFQQQL.EIVDMID....VEDVGAINAKISECVEK...........DPGAFEEEAMVISVEDDDGD--ad.......................
F4C0Q4_METSG/15-179 .....................qgyl-----DPWPPVRGE.YRL..GDPRAGVAVVTL........A.S........V.F...NP...R....-.....-....--...-...G......TAISGPCKTENLGLEKIVAN.VISNSNIRFLIVCGVESK...GHLPGNTLLALHKNGI...dE....K....GR.IIGSKGAIPFIQNLSVQAVERFQRQV.ELIDRIG....LEDMKEIEKLVSQY---...........----------------------nhlampfpeepyqvikrkaarqe..
A0A315Y8R4_9EURY/4-173 .........................KKAPADGWPVISGD.YIV..GDPESPVAVTTL........A.S........H.I...EA...E....L.....S....--...-...G......AAIAGPCKTENLGIEKVVAN.IISNPNIRFLILAGAEVQ...GHITGQSIQALYDNGA...dP....D....KKkIIGATGAIPFVENVPLEGIERFQQQL.EIVDLID....TEDIGAIQSKINECVEK...........DPGALEEDPIVMEVDEENQ---kl.......................
MTXA_METMA/1-142 ........................m--------------.---..---------VTL........A.S........H.L...DA...C....P.....D....--...-...-......AAIWGSSKTENLGVEKIIVN.VISNSNIRYVLVCGTESR...GHLAGHSLLAIHANGI...dE....Q....GR.ITGSQGAIPFIENISGTAVERFQQQV.TVLNRIG....LNDPEEIRRIVEDYRDK...........-GEAYPEEPMLVCAPK------krqts....................
F0T8R8_METLA/4-176 .........................KKSPAEGWPVINGD.YVT..GDPESPVAVATL........A.S........H.N...EQ...I....P.....V....-D...A...G......AAIAGPCKTENLGIEKMISN.LISNPNLRFLILCGAEVQ...GHITGESIKALHENGV...dP....E....KRsIVGAPGAIPYIENVPDAGLDRFRSQF.EIVDLID....VEDAAAIQAKVKECIEK...........DPGAIEEEAMVIEIEEEGEEEE.........................
A0A328SS47_9EURY/4-176 .........................KKEVIEGWPLETGD.YAV..GDAECPVAVVTL........G.S........K.M...NE...E....M.....V....-D...L...G......AAIAGPLHTENLGIEKLVTN.IISNPNLRYLIICGSEVQ...GHITGKTVEALYENGI...dS....E....TKsIIGSPGAIPFVENLPIEAVERFQQQM.SIISMID....NENPDDISEKIQQCIKD...........DPGAFEEDAMIVQLNEKEEQE-s........................
MTRA2_METTH/7-180 .........................KKPVPEDWPHIVGD.YVV..GDEESPVAVVTL........G.S........H.M...ED...E....P.....V....-K...A...G......AAISGPLHTENLGIEKVVGN.VIANPNLRFLVVCGAEVM...GHITGQTMKALHSNGVd..lE....T....GR.IIGATGAIPYIENMPEEAIERFRRQV.ELVDMVD....VEDPDSIAARIQECVVH...........DSGAMEEEPLILKVPEIGKG--dse......................
A0A521EFL4_9BACT/35-188 ......................wdr-----DRWPVTSGN.YLV..GERKSPVAICTL........T.S........P.Q...LM...E....P.....L....QK...A..eG......TAIVGRLVTANLGIEKIIRN.IISNPNIRYLLLCGEDSP...VFHPGQTLHSLFEKGV...dS....D....HR.IIEAQGHYPVLINIDRELIEHFRNHI.VLIDCTG....EGNLDALQRTIMR----...........----------------------lgkaetal.................
L0HHV5_METFS/4-176 .........................KKSPASGWPLIKGD.FHS..GDANSPVAVITM........G.S........H.L...DE...Q....G.....I....CD...A...G......AALCGSCKTENLGLEKVIAN.VIANPNIRFALLVGTEVK...GHLSAQTLVALHKNGV....K....D....GR.VVGAEGAIPFIENLNDTHIKRFQEQV.EIVNIME....TEDVGAVKAKINELKAK...........DPGAFAADPMVVEVKEAAGG--aee......................
A0A060HGZ4_9ARCH/21-158 ................vrhesfggr--------------.---..---GREVAVCTL........G.Sid...lleR.I...SK...S....E.....I....IM...D...R......VAIAGRLLSENKGIDAIIDY.VSAHPDLKRIVVCGREVK...GHMAGQALLALYKNGI...dG....Q....GR.IIGAAGPYPILL-SPREKVEAFRRQV.AIADMTG....ITDLEKIM---------...........----------------------pll......................
Q8PUT0_METMA/1-164 ........................m------GWPVISGD.YIV..GDPKSPVAVVTL........A.S........D.Y...QS...L....N.....L....--...K...N......YAICGTCFTENFGIEKVIVN.VLSNPRISCLVVCGQES-...DHFAGQSLLALAENGV....SafggS....KR.IIGSEGVIPYLDDIPATAISRFLREI.EVIDLVG....TTDPAVIQQAIDSCSGK...........ERGEA-----------------pelsmpeinehsw............
MTRA_METKA/4-181 .........................KAEPAEGWPVVEGD.YVV..GDPEAPVHVVTL........G.S........H.I...EE...D....I.....L....KA...A...Ge...dkVAIAGPCKTENIGIEKVIAN.VIANPNIRFGVLCGAEVT...GHLTGQCFKAMYENGV...dP....D....SGeIIGAEGAIPYLENIPEEAVERYRDQIvELVDLID....VEDVDEIVKAIEECVEK...........DPGAYEEGPMTISLEEEEEEE-l........................
W9DNG2_METTI/4-176 .........................KREPAVGWPILKGE.YDV..GDVNNCVAVVTC........G.S........H.L...AA...G....P.....Q....LD...A...G......ACLTGPCKTENLGLEKVVAH.VISNPNIRFLLVTGSEVK...GHITGEAIIKIHENGV....K....D....NR.IVGATGAIPYVENLSEEAIARFQEQI.ECIDLIG....TEDMGAITGKIKELAGK...........DPGAFDADPMVLEVGEGGDG--dae......................
MTRA_METHJ/4-175 .........................KKSPASGWPIVQGD.FHT..GDPNSPVAVVTM........G.S........H.L...DE...G....A.....I....CS...A...G......AAIAGSCKTENLGLEKVIAN.VISNPNIRFVITCGTEVK...GHLSGQSLIALHQNGV....D....G....GK.IVGSKGAIPFIENLSADNIKRFQEQV.ELVDIME....SEDLGAISAKIKELTAR...........DPGAFDAEAMIVEIKEEGGG--aa.......................
A0A062VAV6_9EURY/2-170 ......................tsv-----PDWPPVRGE.YTA..GDPNKQVAIVTL........A.S........E.L...DK...N....R.....L....IK...-...R......AAIVGTMKTENIGIEKVVAN.IISNTSIRYLVVCGAEVH...GHLSGDAIIALKKSGI...dK....E....GR.ITGAKGAIPYISNIPEDQINIWREQV.EIIDLMN....IENIDSIEKTIDSLTAK...........EPCKW--EPVLVTMGAAKEE--kqe......................
F6BEA3_METIK/4-178 .........................KKAPAAGWPIVSGE.YVV..GNPESCVGVVTL........G.S........H.G...LE...Q....A.....C....ID...A...G......AAIAGPCHTENLGIEKVVAN.YISNPNIRFMVLCGSEVQ...GHITGQCFKALWENGI...gD....D....GG.IIGAKGAIPFLENVGKDAVERFQRQIvEVVDLID....CEDVSKITAAIKECISK...........DPGAIDEEPMVLDLEGGGA---ggee.....................
Q0W334_METAR/4-176 .........................KKEPAKGWPVIKGE.FDV..GDPKSCVAVATA........G.S........H.F...GQ...W....P.....I....-K...A...G......AAISGPFHTENLGIEKIVAN.VISNPNIRFIIITGAEVK...GHISGDALECLHKNGL....K....G....GR.IVGAKGAIPFIENLDDKAVKRFQEQV.QTVYMID....VEDEQKITAAIKDCIAK...........DPGAFAGEPMLLEIKETKIGE-eee......................
A0A8J7W6N0_9FIRM/120-294 .......................qp--ETIKKWPIVEGE.YIV..GNTEASMAICTL........A.D........T.D...LP...N....E.....L....KE...A...Gll..edAAIIGTLSTENLGVERVIRN.LAANPNIRYLILCGKESR...GHRAGQAILSFKDNGV...dQ....D....NQ.ILGAIGPRPVLKNITFDEMEAFRKHI.TVINEIG....TRDISRIAKVVKAYMSK...........PKGAIP----------------ilppkvqmpkvvea...........
MTRA_METST/4-176 .........................KKEVIQNWPLETGD.YAV..GNVESPVAVVSL........G.S........N.M...ND...E....L.....V....-A...A...G......AAISGPLHTENLGIEKVVAN.IISNSNIRYVLICGSEVQ...GHITGKTVEALYENGI...dE....E....KKsIIGSPGAIPFVENLPVEAVERFQKQV.SIVSMIN....NEDVSEISSKIDECISN...........DPGAYDEDAMIVEFNETPEEE-f........................
A0A2K5AP80_9ARCH/17-164 ....................filpi-----------KYD.IFI..GSTSSSIALCTL........A.Sid...lllE.V...SR...S....D.....-....LM...N...S......IAVAGRLLSENKGIDALVRY.VVADKRIRCIVLAGKDSK...GHLAGQSLLALWLNGI...dD....E....GR.IIGSMGKDA-VLTLSKDEVDEFRAQIsTMIDMRG....VTDVDSIRKCI------...........----------------------mvdtt....................
A0A4P2VAP3_9ARCH/1-151 ......................mep------------GD.YVI..GDPSSSIAISTL........S.D........E.E...FL...KqlasR.....L....AR...N...K......YAILGVTRTRNIGVEKLVRN.IAANPHITRLILAGRDSS...TSPVAPVIMELSRHGI....S....G....DG.SVRVQGREVRLRNLSADDVDEFRSRV.RIIDMSG....VRDAEVLLNLVE-----...........----------------------gleqpphqpta..............
A6UWH8_META3/4-177 .........................KKAPASGWPIVSGE.YVV..GNPESCVAVVTL........G.S........H.G...LD...E....A.....A....IE...A...G......AAISGPCHTENLGIEKVVAN.YISNPNIRFMLVTGSEVQ...GHITGQCFKALYENGI...gD....D....GG.IIGAKGAIPFLENAGQDAISRFQNQLvEIVDLID....VEDTGKISSVIKDCISK...........DPGAFEEDPMILDLEGGGGE--ag.......................
A0A8J7RFC5_9EURY/4-176 .........................KTSPASGWPLIKGD.FHS..GDANSCVAVVTM........G.S........H.L...DE...Q....G.....I....CD...A...G......AALCGSCKTENLGLEKVIAN.VIANPNIRFVLLCGTEVK...GHLSGQTLSALHEGGV....E....G....GK.VVGSKGAIPFIENLDDAAIKRFQEQV.EIVNIME....SEDFGEIKAKISELAGK...........DPGAFGEAPIVVEVKEEEG---ggge.....................
F4BZJ2_METSG/4-176 .........................KKKPSDPWPTITGE.YEV..GNPESPVAVCTC........G.S........H.L...HN...A....D.....L....IK...A...G......AALAGPCKTENIGIEKMVAN.VISNPNIRFVLVTGMEVK...GHITGQAVEAFTQSGI...dK....E....GR.IIGAKGAIPFIQNLTPEAIERWKNQV.EAVMMLN....TEDIGAIAGKVKELASK...........DPGALDVEPMAIEIKEGGEEEE.........................
B8GF36_METPE/3-173 .......................kv--RPHPEYPPEEGR.YLR..GNDFSPVAVAIV........L.N........T.D...ED...K...iPpeiehLvrvgVE...T...G......AALSGTVQTPNIGFEKLIWN.IVGNPNIRFLVLGGPESE...GHATGAALKELFKNGI...dE....Q....SR.IVGSDAPFPFLYNIPRPVVNRFLDQV.TLVDC-Q....FQDAATIREAVRACFQE...........QPAVF-----------------rgvmvg...................
V6AVU3_9ARCH/12-154 ..................kavlpir------------ED.VFY..GDPRSSTAICTL........S.S........M.G...LL...R....E.....I....AE...S...Dvi..rrVAVAGRLLSENKGIDALIRS.INKSPNITTLVLCGKDVA...GHRAGHSLLLAHRYGI...dE....N....GR.IVNSLSPNPFLS-VSELEISIFQKQI.RIVDRIG....ITSIQEIQSL-------...........----------------------i........................
A0A2H1EFQ4_9ARCH/15-162 ....................ilpie------------EE.VFF..GNSKSNIAICTL........S.S........I.T...LL...Q....D.....I....SK...S...Pii..ndVAIVGRLLSENKGIDALVRS.MLSNKKIDTLILYGKEVL...GHKSGDSLICLHKNGI...dE....N....HR.IMGSSSPHPIL-TLTKKQVLEFQNQV.KIINKIG....ETSISKLTGIVESL---...........----------------------kktq.....................
A0A1X0Q8T9_9MICR/1-161 ......................mky---RSNEWPTMYSDkIII..GNLKSNVAVTTL........W.T........V.R...EK..vA....D.....I....LD...S...N.....dFCLVANFYDAFNGIEPLIRN.CLANTNIRYILVVGNDRA...--KSKKTLINFFKSEL....K....N....HI.VTDT--EVPLPEEIPLDELNKLIRNV.QVIDLTDkitkIDDFDQYKTVIYDCIK-...........----------------------tlsklepyd................
D5E9T3_METMS/2-157 .......................dt---VSEKWPVTKGD.FSA..GNTKSCIAVVTL........A.S........S.M...PL...F....E.....K....--...-...-......AAIWGSCKTENLGAEKVVMN.VVSNCNIRYVLLCGGESR...GHLAGQTLKALYENGI...dE....D....GR.ILGSEGAIPFIENLEIETIQRFRQQV.ELIDRIG....LTDLDEICSIVDNYHD-...........----------------------sekpfeafpvs..............
F7XQ94_METZD/4-175 .........................KREPAPEWPILKGE.YDI..GDVKNCVAVITL........G.S........H.L...PA...E....P.....Q....LE...A...G......AAITGPCKTENLGLEKVLAH.IISNPNIRYLLITGSEVK...GHITGDAFLKIHQNGV....K....E....NR.IVGAVGAIPYVENLTPEAIERFQQQI.ECVDLIG....TENMSEITSKIKELASR...........DPDAFDADPMVVKVGEDGAEEE.........................
A0A2H5X395_9BACT/106-267 ....................vrtdv------SWPAVAGE.YLV..LDQCGTVAVSTL........A.S........A.D...LP...Ek.laQ.....L....RP...S...G......LAIVGKTETENIGIDKVVKN.IITNSCIRTLIVSGQEPK...GHMAGQALLSLWENGI...dE....Q....QR.IVGAQGKRPFLRNVTAQEIEQFRQQV.VVVDLIG....CDDAERIAAEVANYAQ-...........----------------------ehlcscqsap...............
A0A7X8N8W7_9FLAO/38-208 ......................fnt----KQKWPVVSGN.YKV..VNATHPIAVCTL........T.S........T.N...LI...Q....P.....I....SQ..wE...N......IAIVGNLYTPNLGIEKIIKN.IVSNPNIRVLVLCGKDSP...IFKAGQAIQCLFKHGI...tS....E....KR.IRNAQGHFPVLQNLSIEKIDQFLKQV.ELIDNRE....NIEVDLLHKKISKIDLK...........NN--IEVKNVLLKSEQ------tdmeee...................
G7WPT7_METH6/4-176 .........................KKPTSDPWPWLTGE.YVV..GNPESPVAVVTC........G.S........H.L...NN...A....P.....F....ID...A...G......SALAGPCKTENIGIEKMVAN.IISNPNIRFLIITGMEVK...GHITGQAIEAFAANGI...dQ....E....GR.IVGATGAIPFIQNLTPEAIERFKQQI.TTINIID....TEDTGTIVSKIKECVSK...........DPGALDVEPMAVEISEGEAEEE.........................
A0A0X3BMW3_9EURY/4-175 .........................KKSPASGWPIVQGD.FHT..GDAQSCVGVVTM........G.S........H.L...DE...Q....G.....I....CD...A...G......AAIAGSCKTENLGIEKIIAN.VISNPNIRFILCCGTEVK...GHLSGQSFMALHAGGV....S....G....GK.IVGAEGAIPFIENLSDEAIKRFQDQV.EMVNIME....SEDMGTIKAKIDELKAK...........DPGAFPEEPMVVEVKEAGGG--aa.......................
J9Z8W3_LEPFM/11-182 .......................pk---AQEGWPPLPGD.YRV..LRYQAPVAVCTL........S.D.......iR.L...FE...T....L.....S....KS...A...Gt....gLSIIGTLHTENLGIERIITN.VLGNPHIRFLIVCGADSRqsvGHLPGQSLVSLMSAGL...dE....K....GK.INGALGKRPILKNIGRDAVEHFRNVI.TLLDMRG....VENQDEILARIRECTTR...........NPGRSD----------------pfpslptiev...............
MTRA_METAC/4-175 .........................KKEPASGWPILKGE.YEV..GDVKGCVAVITC........A.S........H.L...PG...K....P.....V....LD...A...G......AAITGSCKTENLGIEKVVAH.VISNPNIRYLVVTGAEVK...GHVTGQAMLSIHANGV....K....E....HR.IVGAVGAIPYVENLNDDAVARFQQQI.ETVNLLD....TEDMGAITAKVRELVAK...........DPGAFDAEPMVVEISEEGEEEE.........................
A0A1D3L4Q6_9EURY/4-177 .........................KKSPAEGWPVVNGD.YVV..GDPESPVAAVTL........A.S........H.I...ED...V....P.....A....-E...A...G......AAIAGPCKTENLGVEKVIAN.IISNPNIRFLILCGAEVQ...GHITGQSIQALHENGV...dP....E....KRsILGATGAIPYVENVPDEGIERFQQQL.ELVDLID....VEDPASIQSKVKECIEK...........DPGAFEEEAMVIEISEEDGEEEe........................
A0A2H5VDH7_9ARCH/16-163 ....................filpi-----------KYD.IFI..GSTSSSIALCTL........A.Sid...lllE.V...SR...S....D.....-....LM...N...S......IAVAGRLLSENKGIDALVRY.VVADKRIRCIVLAGKDSK...GHLAGQSLLALWLNGI...dD....E....GR.IIGSMGKDAVL-TLIKDEVDEFRAQIsTMIDMRG....VTDVDSIRKCI------...........----------------------mvdtt....................
C1F4T6_ACIC5/100-275 ......................dee----RAGWPPLPGD.FKV..IRYGAPVAVCAL........N.S........T.E...LM...K....T.....L....TE...ArpdG......LAIVGTMHTENLGIERVIRN.TLANPNLRFLVICGTDTQqtvGHLPGQSLHSLFQNGL...dE....K....GR.IVGAKGKRPVLKNVTREEVQAFLAQV.EPVSMIS....EENPATVTEQITACARR...........DPGIYPWPA-------------gtvsverirar..............
A0A483CUU9_9EURY/4-175 .........................KTSPASGWPLIKGD.FHS..GDANSCVAVVTM........G.S........H.L...DE...Q....A.....I....CD...A...G......AALCGSCKTENLGLEKVIAN.VISNPNIRFVITCGTEVK...GHLSGQTLIALHANGV....E....G....GK.VVGSKGAIPFIENLDDSAIKRFQAQV.ELVDIME....AEDLGAIKAKINELAGK...........DPGAFGEPPMVIEVKEAEGG--aa.......................
Q12TW9_METBU/4-135 ......................yek--------------.---..------------........-.-........-.-...--...-....-.....-....--...-...-......AAMWGSCKTENLGAEKIIIN.TISNSNIRYVLLCGNESK...GHLAGQTLIALHKNGI...dN....D....GR.IIGSDGAIPFVENIGKDAIERFQKQV.TIIDHIG....LTDLDEIYNIVDEYSSK...........GS-PYSEGPFVVEVVTK-----rktv.....................
D7DUI1_METV3/4-177 .........................KKAPATGWPVANGE.YVV..GNPESCVAVVTL........G.S........H.G...LD...E....A.....A....IE...A...G......AAISGPCHTENLGIEKVIVN.YISNPNIRFMVVTGSEVQ...GHITGQCFKALYENGI...gD....D....GG.IIGAKGAIPFMENVGQEPVARFQNQIvELIDMID....SEDKGKIQQTVKDCISK...........DPGASEEDAMVIDLEGKAGE--ag.......................
I0INS9_LEPFC/103-274 .......................pk---AQEGWPPLPGD.YRV..LRYQAPVAVCTL........S.D........V.RlfeTL...S....K.....S....VE...T...G......LSIIGTLHTENLGIERIITN.VLGNPHIRFLIVCGADSRqsvGHLPGQSLVSLMSAGL...dE....K....GK.INGALGKRPILKNIGRDAVEHFRNVI.TLLDMQG....VENQDEILARIRECTTR...........NPGRSD----------------pfpslptiev...............
MTRA_META3/4-177 .........................KKAPASGWPIVSGE.YVV..GNPESCVAVVTL........G.S........H.G...LD...E....A.....A....IE...A...G......AAISGPCHTENLGIEKVVAN.YISNPNIRFMLVTGSEVQ...GHITGQCFKALYENGI...gD....D....GG.IIGAKGAIPFLENAGQDAISRFQNQLvEIVDLID....VEDTGKISSAIKDCISK...........DPGAFEEDPMILDLEGGGGE--ag.......................
MTRA_METV3/4-179 .........................KKAPATGWPVANGE.YVV..GNPESCVAVVTL........G.S........H.G...LD...E....A.....A....IE...A...G......AAISGPCHTENLGIEKVIVN.YISNPNIRFMVVTGSEVQ...GHITGQCFKALYENGI...gD....D....GG.IIGAKGAIPFMENVGQEPVARFQNQIvELIDMID....SEDKGKIQQTVKDCISK...........DPGAFEEDAMVIDLEGKAG---gagee....................
U6E9X4_9EURY/3-175 ........................g-KKSVQEWPPVVGD.YTI..GDVESAVAVVTL........G.S........H.M...ED...I....P.....V....-N...A...G......ASISGPLHTENLGIEKVIAN.VVSNPNLRFLVVCGAEVQ...GHITGQSIKALHENGAd..pE....K....KR.INGATGAIPYVENLNEEAIQRFQDQV.EVIDMVN....VEDPHQIQAQIKECLAQ...........DSGAFEEESLVIQLPKKGA---hpt......................
A0A1F2P5I4_9EURY/11-203 ........................k-VKPPSDYPPEEGR.YVR..GNDYSPVAVCVI........L.DtfdfaipmE.L...EDl.vM....E.....A....LD...A...G......AALSGMLQRENIGIEKLICN.IVSNPNIRYLIVCGREAY...GHLPGETLRNLIENGI....D....E....NGwIIGARALTPYLPNIPKEAIERFRRQI.KLIDLVG....CLDPERVKAAVRACYQE...........KPTRFEN---------------yvlydpgaypddpicvklrmkinkp
F6BEA2_METIK/4-179 .........................KKAPAAGWPIVSGE.YVV..GNPESCVGVVTL........G.S........H.G...LE...Q....A.....C....ID...A...G......AAIAGPCHTENLGIEKVVAN.YISNPNIRFMVLCGSEVQ...GHITGQCFKALWENGI...gD....D....GG.IIGAKGAIPFLENVGKDAVERFQRQIvEVVDLID....CEDVSKITAAIKECISK...........DPGAIDEEPMVLDLEGGGA---ggeee....................
K0IN48_NITGG/13-157 .................kvceavlp----------IKHE.YHL..GMGKE-LAICTL........S.Smd...lleK.L...SK...S....D.....P....VM...N...K......IAIAGRLLSENRGIDAMIKF.ALDHPELRRIIVCGKEVK...GHRAGQALLALARNGI...dR....N....GR.IVGALGPYPILES-PAGDVDAFRQQV.EILDMIG....TTDIEKL----------...........----------------------lva......................
A0A2Z4L910_9EURY/4-177 .........................KKDVIEGWPLETGD.YDV..GDIQCPVAVVTL........G.S........K.M...NA...D....V.....V....-Q...R...G......AAIAGPLHTENLGIEKVVAN.VISNSNIRFVIVCGSEVQ...GHITGKTMEALYENGI...dP....E....KKvILGSPGAIPFVENLSVEAVERFQDQI.TLISMIN....NENLDEIEEKISECIAN...........DPGAYPQDAMIVELNDVKDEE-dd.......................
A0B8Y2_METTP/4-176 .........................KKKPAEPWPVITGE.YEV..GNPESPVAVVTC........G.S........H.L...NN...A....E.....L....VA...A...G......AALAGPCKTENIGIEKMVAN.VISNPNIRYLIITGMEVK...GHITGQAIEAFTASGI...dK....E....GR.IVGAKGAIPFIQNLTPEAIERWRQQI.TTINMID....TEDMGAITAKIKELVAK...........DPGALDVEPMIVEIKEGAGEE-g........................
A0A2V3JFY1_9EURY/3-175 ........................k-SATTDPWPPLPGE.FEI..GNPENCVAVTTC........G.S........H.L...SD...F....P.....I....-G...A...G......ASITGPTKTENIGIEKLVAN.IVSNPNIRFLIVTGMEVK...GHITGQAITAFHQNGI...dQ....D....GR.IIGSVGAIPFIQNLDDDAIKRFQEQIvECVDLID....TEDEGKITAAIKACVAK...........DPGALDVEPMEVKIEESGGEEE.........................
A0A7R6WCH7_9GAMM/115-292 .....................tpee----QIGWPPFPGD.YQV..QSYQASVAVCTL........N.S........D.D...LM...K....Q.....L....IAeniQ...G......ISIIGSLHTENLGIEHIIRN.ISTNPNIRFLLICGEDTQkaiGHLPGQSLVCLFQYGV....D....E....KKrIINAQGKRPFLKNITKEQIDHFLQQV.SVVENIS....VTDIDKIKESIGQLVAK...........QVGTFDQEIMEIS---------pieiepvs.................
Q0W333_METAR/4-176 .........................KKEPAKGWPVIKGE.FDV..GDPKSCVAVATA........G.S........H.F...GQ...W....P.....I....-K...A...G......AAISGPFHTENLGIEKIVAN.VISNPNIRFIIITGAEVK...GHISGDALECLHKNGL....K....G....GR.IVGAKGAIPFIENLDDKAVKRFQEQV.QTVYMID....VEDEQKITAAIKDCIAK...........DPGAFAGEPMLLEIKETKIGE-eee......................
A0A2H5XER2_9BACT/106-274 .....................vrtd-----GDWPIVAGE.YFV..LDREGSVAVSTL........A.S........T.D...LP...Ek.laQ.....L....RP...R...G......LAIVGKTETENIGIDKVIKN.IVTNPCIHTLIVAGQEPK...GHMSGQALLALAENGV...dE....R....QR.IIGAKGKRPFLRNVTLQEIEHFRQQV.TVVDLIG....CEDAERIAAEVEARAQA...........----------------------rpcgcqgvlrqdaimq.........
A0A8J7UPH3_9EURY/4-175 .........................KTSPASGWPLIKGD.FHS..GDANSCVAVVTM........G.S........H.L...DE...Q....G.....I....CD...A...G......AALCGSCKTENLGLEKVIAN.VIANPNIRFVLLCGTEVK...GHLSGQTLRALHEGGV....E....G....GK.VVGSKGAIPFIENLDDAAIKRFQEQV.EIVDIME....SEDFGEIKAKISELAGK...........DPGAFGEAPIIVEVKEAEGG--ae.......................
A0A8K0Y3E9_9ARCH/16-157 ..................lpiedrv--------------.-YF..GDSKSSVAVCTL........S.S........M.K...LL...E....E.....I....VS...S...Tlm..tkVNIAGRLLSENKGIDLLVRH.VISDGNIRVIILCGRDTV...GHRPGHSLLCLHQNGM...dF....D....GK.IIGSKSPDPIL-SLTNEEVSRFQNQV.RIIDKMG....ETDISNL----------...........----------------------gpeigg...................
MTXA_METAC/1-167 ........................m-KTIAENWPPVRGD.YVT..GKPDSRIAVVTL........A.S........H.L...EA...F....P.....N....--...-...-......AAIWGSSKTENLGVEKIIVN.VISNSNIRYVLVCGTESR...GHLAGHSLLAIHANGI...dE....K....GR.IVGSQGAIPFIENISREAVDRFQRQV.TLLDRIG....LNDPEEIRKIVEDYRDK...........-GEVYPEEPVVVCAP-------kkrqas...................
S2E6G3_9ARCH/10-150 ..................lpipeea--------------.-YL..GNADSSIAVCTL........S.S........I.N...LL...K....Q.....I....SN...S...Dll..nhVGIAGRLFSENKGIDSLIRY.INQNKKIKTILVCGKEVW...GHKAGHSLFELHKNGI...dN....R....GR.IINSTSPDPFLT-VTKSEIIYFQNEI.TLVNLIN....EINFETIKKSI------...........----------------------i........................
A0A484F5X7_9EURY/6-177 .........................KSQAAAGWPMLKGE.YRT..GSTESCVAVVTC........G.S........H.L...DD...E....A.....L....AA...A...G......AAISGSCKTENLGIEKLVSH.IISNPNIRYLIVCGAEVK...GHITGEAILMLHQNGI....S....K....NR.IVGAKGAIPYIENLSEEAVKRFMEQI.ECIDMIN....VEDIGEISEKIKECIAN...........DPGAFPAAPLIQDVKEKTNG--td.......................
A0A1G5S0A0_9FIRM/4-149 .......................lt--------------.---..--PESSIGVVTL........A.T........A.G...LVerlA....E.....L....KP...N...G......LSIVGKLETENIGIEKIIQN.TLAAANIKVLILCGKDSE...GHFAGQTLEALVNNGV...dD....A....MR.VVGSKGRKAVLANASREEIEAFRTQV.TVINRIG....LQDEAEILREIEA----...........----------------------qsectrsqeqgiq............
A0A1D2W9U9_9EURY/4-176 .........................KKKTAEGWPVVNGD.YVV..GNPKSCVAGATL........A.S........H.L...ED...V....I.....V....-D...A...G......AAIAGPVKTENLGIEKMIAN.LISNPNIRFLLLCGSEVQ...GHITGQSIEALHANGV...aP....D....KRrIVGATGAIPYIENVPDEAIDRFRQQL.EIVSLID....SEDMDLIRARVKECVEK...........DPGAAEEETVIIQLEENCEE--vk.......................
A0A4E0QC44_9EURY/1-44 .......................mn----TSNWPVTDGD.YVI..GEPDSPVAVVTL........A.S........D.Y...KD...M....D.....C....IH...-...-......--------------------.------------------...----------------....-....-....--.--------------------------.-------....-----------------...........----------------------dscaee...................
A0A1B4V6T0_9GAMM/19-179 .....................tkpr----RRTWPYVPGS.YFV..SDPDAPVAVTTL........G.S........V.A...LA...E....A.....V....SRnppS...G......LCIVGKVETENIGIEKIVKN.VLSNPAIRYLVCAGNEPP...RHLTGATLLALFANGI....D....E....RKrIPGSPGMRPVLPNTSAAEVQAFREQV.QPVDMIG....CTDVSAIHARVAELTRS...........----------------------aapatgp..................
A0A1V6N4F9_METAZ/4-176 .........................KKSPAEGWPIINGD.YIA..GDPESPVAVTTL........G.S........H.N...ED...V....P.....A....-N...A...G......AAIAGPCKTENLGIEKVVAN.IISNPNIRFLILCGSEVQ...GHITGQSFEALHQNGV...dP....E....KRsIMGATGAIPYVENIPDEGIERFQSQL.EIVNMID....VEDAGAIEAKVKECIEK...........DPGAFEEDAYVISLDDSGDEE-d........................
A0A062V305_9EURY/4-175 .........................KVKPADGWPVVKGE.YEA..GNPENPVAVSTC........G.S........H.L...KG...A....A.....Q....LA...A...G......AAITGSQKTENLGIEKIVAN.VISNPNIRFLLVTGAEVK...GHISGEAIIMLHKNGI....K....D....NR.IVGSTGAIPYIENLPDDAIKRFQAQV.QVFDMIG....TEDEGAIIAKIKELASK...........DPGAFEGEPMIIQVGEKEEV--ae.......................
I7J9J6_METBM/4-175 .........................KKSPASGWPIVQGD.FHT..GDAQSCVGVVTM........G.S........H.L...DE...Q....G.....I....CD...A...G......AAIAGSCKTENLGIEKIIAN.VISNPNIRFILCCGTEVK...GHLSGQSFIALHAGGV....S....G....GK.IVGAQGAIPFIENLSDEAIKRFQDQV.EMVNIME....SEDMGTIKAKIDELKAK...........DPGAFPEEPMIVEVKEAGGG--aa.......................
A7I5S6_METB6/4-176 .........................KKSPASGWPLVKGD.FHS..GDANSPVAVITM........G.S........H.L...DE...Q....G.....I....CD...A...G......AAMCGSCKTENLGLEKVIAN.YIANPNIRFVLLCGTEVK...GHLSAQSLIALHKGGV....K....D....GR.IVGAEGAIPFIENLNDAAIKRFQEQV.SIVNIME....TEDLNAIKAKINELKAK...........DPGAFAADPLVVEVKEAAA---ggge.....................
A0A1D2WB62_9EURY/4-175 .........................KKSPAEGWPVVNGD.YIV..GDPESPVAATTL........G.S........H.N...ED...V....V.....A....-A...A...G......TALAGPCKTENLGVEKMVAN.LISNPNIRFLILCGSEVQ...GHITGQSIEALHANGV....D....E....KRkIAGATGAIPFIENIPDEGIERFQQQM.EIISMID....IEDAGQIQAKVKECIEK...........DPGAFEEEAMVIKVEEGGAEEE.........................
A0A166CFB8_9EURY/4-176 .........................KKEAAEGWPIVNGD.YIA..GDPESPVAVATL........A.S........H.N...ED...I....G.....A....-N...A...G......AAISGPCKTENLGVEKVVAN.IISNPNIRFLILCGAEVQ...GHITGQSIEALHQNGV...dP....E....KRsIVGATGAIPYVENIPDEGIERFQQQV.EIVNMID....SEDAGAIESKVKECISK...........DPGAFEEEALVISVDDAGGDD-d........................
A0A0E3P281_9EURY/4-175 .........................KRDPAPGWPILKGE.YEV..GDVQGCVAVITC........A.S........H.L...PG...K....P.....V....LD...A...G......AAITGSCKTENLGIEKVVAH.VISNPNIRYLVVTGAEVK...GHITGQAALSLHENGV....K....E....NR.IVGAIGAIPYVENLNPEAVERFQAQV.ETVELLN....TEDMGVITAKVKELVSK...........DPGAFDAEPLVVEISEEGEGE-e........................
H1YXH2_9EURY/4-175 .........................KKSPASGWPKIQGD.YHA..GDAESPVVVVTV........G.S........H.L...DE...Q....A.....V....CD...A...G......AAMCGSCKTENLGLEKIVAN.VIANPNIRFIITCGTEVK...GHLSGQCLIALHANGL....E....G....GK.IVGAKGAIPFIENLTDEGVQRFREQV.EIVDIME....SEDMGTIKAKIEELKGR...........DPGAFDGDPIVIEVKEDGA---ggd......................
A0A0E3L195_9EURY/1-166 ........................m--KVAENWPVVKGD.YRV..GNPESRIAVVTL........A.S........H.L...EA...Y....P.....E....--...-...-......AALWGSSKTENLGVEKIIVN.TISNSNIRYILVCGTESR...GHLAGQSLLAIHAGGI...dE....Q....GR.IIRSEGAIPFIENVPGEAVERFQQQV.IMLDRIG....LNDTEEIRKIVDEYRNK...........N-EAYPEEPLVVCS--------pkkkqcs..................
A0A3B0B3Q5_9ACTN/2-156 ...............vrtgegtaep--------------.---..--APARVAVCTL........S.S........R.E...LV...G....P.....L....AR..lP...G......VALAGTLMTANLGIEEIVRA.LARDHTVRGLLVCGRDSP...RFQAGQSLVALFRRGLr..pG....S....AR.IPGATGHLPVLRSVTRREVEEVRARV.ELVDLRG....ERDPLELSTAVAALLSA...........----------------------vrdttagdrlp..............
A0A1D2W6E8_9EURY/4-175 .........................KKQAAEGWPQIVGD.YKV..GDEESAVAVVTL........G.S........H.M...ED...M....P.....V....-K...A...G......ASISGSLHTENLGIEKVIGN.VVSNPNIRFLVVCGAEVQ...GHITGQTIKALYENGV...dA....K....KR.IVGAEGAIPYLENVTEDAIERFRNQI.EIVDLVD....TENSEAINSKIEGCLIH...........DAGAYEEETVVIPLLEKQKD--ss.......................
D7E9H2_METEZ/4-170 ........................l-KRIADDWPVVKGD.YTV..GNPESRIVVVTL........A.S........S.I...ES...N....P.....E....--...-...-......ACLWGTCKTENLGAEKLITN.IVSNSNIRFVLLCGGESR...GHLSGHTILKLHKNGV...dG....K....GR.IIGSEGAIPFVENIPRIAIQRFRNQV.EVIDCIG....ETDSEV-LGNIVDTYKD...........KRDAYNEEPVLVTSKSRK----kkt......................
A0A562JHZ4_9FIRM/3-161 .......................nl--------------.---..-DELSPVAISTL........SnS........K.L...AD...El..aG.....L....KP...K...G......LSIVGKTETENIGVEKIIKN.VLAVPSIKYLILCGKDSE...GHYSGNTLMKIFENGV...dN....N....NK.VIDSKGRKPVLINTLKEEIESFRKNV.IVINMIG....CENTNNILDKIEELRKK...........GF--------------------qihdniniksaenkahntn......
A0A1F2P9Q7_9EURY/5-197 ........................k-VKPPSEYPPEDGR.YVR..GNDYSPVAVCVI........L.DtfdfaipmE.L...EDl.vM....A.....A....VD...A...G......AALSGMLQTENIGIEKLICN.IVANPNIRYLIICGREAW...GHLPGDTLIKLVENGV....D....E....RGwIIGSTALTPYLPNIPEEAIEQFRRQI.RIIDLID....CLDADKVTDAVRACYQEepsqfenytlyDPGAYAEDPICVKIS-------mkiekp...................
MTRA1_METRM/4-176 .........................KKPAADNWPVVSGD.YIV..GDPESPVAVTTL........A.S........H.N...ED...I....P.....A....-A...A...G......AAIAGPCKTENLGIEKVVAN.IISNPNIRFLILCGAEVQ...GHITGQSIQALHENGCd..pE....K....KK.ITGATGAIPFVENIPMEGVERFQQQV.ELVDLID....NEDGGAITAKVKECIEK...........DPGAFEEDAMVIEVKEGDDDE-d........................
A0A2V3JCJ5_9EURY/4-180 .........................KKKPADGWPLASGD.YVV..GNPENPVAVSSS........G.G........H.F...KDadaQ....A.....L....LD...A...G......ASIVGSCKTENIGLEKQIAN.IVGNPNIRFYIVAGPEVP...GHICAGSMKKLHEKGVd..pE....S....HK.IIDAPGAIPFIENVPHEAVERFRQQV.ELIDMIG....VEDVAQIKAKVEECVAR...........DPGAFPADPMVVKIAEEEAEE-a........................
D5E6K1_METMS/61-197 ................gykkpclqn--------------.---..------------........-.-........-.-...--...-....-.....-....--...-...-......YAICGTCFTENFGIQKVIAN.ILSNPKINCLIVCGKESK...-HFAGQSIIALVENGVs.tmA....D...yKK.IIGSKGVIPYLDEIPMTAINHFLKEI.EVIDLID....TTDPETIQKVIDSCKLK...........ERS-------------------eakkypipqidens...........
A0A484IFT6_9ARCH/24-163 syyegngdlisictlssidllkkia--------------.---..------------........-.-........-.-...-R...D....N.....N....IM...E...K......VVLAGRLFSENKGIDSLVTFcCIRSLDMKYLILCGKDTK...GHYPGDALMNLMNYGI...dT....E....GR.IINCIAPYPYLT-INSHLVDKFRKKI.TIIDMRG....CLDLYEIKNKIKI----...........----------------------li.......................
L0HFU1_METFS/4-175 .........................KKSPASGWPLIKGD.FHS..GDANSSVAVITM........G.S........H.L...DE...Q....G.....I....CD...A...G......AALCGSCKTENLGLEKVIAN.VIANPNIRFALLVGTEVK...GHLSAQTLVALHKNGV....K....D....GR.VVGAEGAIPFIENLNDTHIKRFQEQV.EIVNIME....TEDVGAVKAKINELKAK...........DPGAFAADPMVVEVKEAAGG--qe.......................
MTRA2_METRM/4-176 .........................KKPTAENWPVVSGD.YIV..GDPESPVAVTTL........A.S........H.N...ED...I....P.....A....-A...A...G......AAIAGPCKTENLGIEKVVAN.IISNPNIRFLILCGAEVQ...GHITGQSFKALYENGCd..pE....K....KK.ITGATGAIPFVENIPMEGVERFQQQL.ELVDMID....NEDGGAITAKVKECIEK...........DPGAFEEDSLVIKIDEER----yskk.....................
A0A4E0Q7M2_9EURY/4-175 .........................KRDASPNWPMLKGE.YDV..GDIQNSVAVITC........G.S........H.L...EA...G....P.....Q....LD...A...G......AAITGPCKTENLGIEKVVAH.IIANPNIRYFIVTGAEVK...GHITGQAFIALHQHGV....K....D....NR.IVNATGAIPYIENLNEEAIARFQEQV.EIIDFIG....TEDMNSIVSKIKEYASK...........DTDAFDAEPMEIVVGEGGAEE-g........................
D5E6K1_METMS/5-52 ......................kst---DPNNWPMEEGD.YVI..GDPDSPVAVVTL........T.S........D.Y...RN...M....D.....C....I-...-...-......--------------------.------------------...----------------....-....-....--.--------------------------.-------....-----------------...........----------------------hdpcedgtp................
D1YVZ3_METPS/4-174 .........................KKEPAKGWPVVKGE.YDT..GDAKSPVAVATC........G.S........H.F...NL...F....P.....I....-K...A...G......AAISGPFKTENLGIEKIVAN.VISNPNIRFLVICGSEVK...GHISGDALICLYKYGL....K....D....GR.IVNAKGAIPFIENLDANAVKRFQEQV.QIFEMVD....VEDEAKITQVIKDCLAK...........DPGAFAGEPMLITIKEKEEE--ve.......................
E3GWY7_METFV/4-167 .........................KKEPAEGWPVVSGD.YIV..GDPESPVAAVTL........A.S........H.I...ED...I....P.....I....-D...A...G......AAIAGPCKTENLGIEKVIAN.IISNPNIRFLVLCGSEVQ...GHIVGQSMKALHKNGV....D....D....KRkIIGAKGAIPYIENLPEEALERFQKQV.EIVDLID....VEDADQIKEKVKECIEK...........DPGAFEEEEVILR---------l........................
A0A166F2M3_9EURY/4-176 .........................KKSPAEGWPIINGD.YIA..GDPESPVAVTTL........G.S........H.N...ED...V....P.....A....-N...A...G......AAIAGPCKTENLGIEKVVAN.IISNPNIRFLILCGSEVQ...GHITGQSFEALHQNGV...dP....E....KRsIVGATGAIPYVENIPDAGIERFQQQL.EIINMID....VEDAGAIESKVKECIEK...........DPGAFEEEALVISVDDKDEEE-d........................
A0A0E3NXE8_9EURY/1-163 ........................m------EWPVTPGD.YVV..GDPNSPVAVVTL........A.S........D.Y...RS...L....N.....L....--...K...N......YAICGTCFTENFGIEKVIVN.VLSNHRISCLLVCGKES-...DHFAGQSLLALAENGVs.afG...gS....RK.IVGSEGVIPYLNEIPATSISRFLREI.EVIDLVE....TTDPAVIQQAIDSCSGE...........ERGE------------------apelsmpeidehs............
A9A2W6_NITMS/13-155 ....................kvvlp----------IKQE.FYL..GNPNSQIAICTL........A.Sis...lldD.L...KD...S....E.....L....-L...S...K......VAIIGRLFSENKGIDSMIQY.VYENKNITKIILCGKEVW...GHKSGHSLLQLHKNGI...dK....N....SR.IINSVSPDPYLT-VSKDMIEYFQKNI.SIVDLID....ETNLEVISKK-------...........----------------------l........................
A0A0X3BPL6_9EURY/1-82 ......................mpg--------------.---..------------........-.-........-.-...--...-....-.....-....--...-...-......--------------------.------------------...--------------GV....S....G....GK.IVGAEGAIPFIENLSDEAIKRFQDQV.EMVNIME....SEDMGTIKAKIDELKAK...........DPGAFPAEPMIVEVKEAGG---agae.....................
A7I5S4_METB6/4-175 .........................KKSPATGWPLVKGD.FHS..GDANSPVAVITM........G.S........H.L...DE...Q....G.....I....CD...A...G......AAMCGSCKTENLGLEKVIAN.YIANPNIRFVLLCGTEVK...GHLSAQSLVALHKGGV....K....D....GR.IVGAEGAIPFIENLNDAAIKRFQEQV.SIVNIME....TEDLNAIKAKINELKAK...........DPGAFAADPLVVEVKEAAA---gga......................
I7KDB4_METBM/4-175 .........................KKSPASGWPIVQGD.FHT..GDAQSCVGVVTM........G.S........H.L...DE...Q....G.....I....CD...A...G......AAIAGSCKTENLGIEKIIAN.VISNPNIRFILCCGTEVK...GHLSGQSFIALHAGGV....S....G....GK.IVGAQGAIPFIENLSDEAIKRFQDQV.EMVNIME....SEDMGTIKAKIDELKAK...........DPGAFPAEPMIVEVKEAGG---aga......................
A0A7J0CEE5_9ACTN/2-143 ..................vngpggv--------------.---..-----EVAVCSL........S.S........R.E...LV...E....P.....L....SR..lP...G......VALAGTLMTANLGIEELVRT.LARRPAIRGLVVCGRDSP...RFLAGQSLLALFRNGV...dP....E....LRrIVGAAGHLPLLRSVPLHEVERLRSRL.EVVDARG....EGDPLA-----------...........----------------------lgeivrqlwgriraa..........
B8GE98_METPE/4-175 .........................KKSPASGWPIVQGD.FHS..GDANSPVAVITM........G.S........H.L...DE...Q....G.....I....CD...A...G......AAICGSCKTENLGLEKVVAN.VISNPNIRFVLLCGTEVK...GHLSGQSLRQLHSSGV....D....K....GK.IVGSEGAIPFIENLDDAAIKRFQEQI.EIVNIME....SEDLGTIKAKINELKGK...........DPGAFAGDAMVVEVKEAGGA--ae.......................
MTRA_METEZ/4-176 .........................KKEPAEGWPILKGE.YEV..GDPNNCVAVITC........G.S........H.L...EG...Q....P.....M....LD...A...G......ASIVGPCKTENLGLEKVVSH.IISNPNIRYLIVTGAEVK...GHITGEAMMMLHKNGV....K....D....NR.IVGATGAIPYVENLTEESVERLQQQLeECVDLLG....TEDLNTITSKIKELAEK...........DPGAFDAEPMIIQLEEEEEEEE.........................
A0A8J7WAV0_9EURY/4-176 .........................KKSPASGWPIAQGD.FHS..GDANSCVAVVTM........G.S........H.L...DE...A....G.....I....CA...S...G......AALCGSCKTENLGLEKIIAN.IISNPNIRFVLLCGTEVK...GHLSGQSLEALHKSGV....S....G....GK.IVGAEGAIPFIENLDDAAIKRFQEQV.ELANIME....TEDLGQIKAKINELTGR...........DPGAFAGDPMVIEVKEAGG---ggae.....................
A0A447G1P4_9ARCH/20-161 .................pvpdvmyg--------------.---..GDPGSRVAVCTL........G.S........H.G...LL...S....G.....VgrsdVM...G...H......VRVAARLLSENRGIDGLVRA.A-CGMGLRGIVVCGRDVR...GHMPGHSLVMLHRNGT...dG....A....GR.IIGSSSPDPRLR-CDPVHVAHFRRMI.-LEDLRG....VEDLD------------...........----------------------mvrdissrlaa..............
B8GEA0_METPE/4-175 .........................KKSPASGWPIVQGD.FHS..GDANSPVAVITM........G.S........H.L...DE...Q....G.....I....CD...A...G......AAICGSCKTENLGLEKVVAN.VISNPNIRFVLLCGTEVK...GHLSGQSLRQLHSSGV....D....K....GK.IVGSEGAIPFIENLDDAAIKRFQEQI.EIVNIME....SEDLGTIKAKINELKGK...........DPGAFAADAMVVEVKEAGGS--te.......................
A2STR2_METLZ/4-175 .........................KKSPANGWPIIQGD.YHT..GDANSPVAVITM........G.S........H.L...DE...A....G.....I....CA...A...G......AALAGSCKTENLGIEKVVAN.VISNPNIRFVLLCGTEVK...GHLSGQSIEAMHKNGV....E....G....GK.IVGSTGAIPFLENLTAEHIKRFQEQI.ELVNIME....TEDMGQISAKINELKGR...........DPGAFAADPIVIQLTDDAGG--ae.......................
Q2FRN1_METHJ/4-175 .........................KGEAASGWPIVQGD.FHT..GDSKSPVAVVTM........G.S........H.L...DE...G....A.....I....CS...A...G......AAIAGSCKTENLGLEKVIAN.VISNPNIRFVITCGTEVK...GHLSGQSLIALHQNGV....D....G....GK.IVGSKGAIPFIENLTGDHIKRFQEQV.EIVDIME....SEDIGAISAKINELKAR...........DPGVFPGGPMVVEIKEEGG---ggg......................
G7WNE2_METH6/27-186 ......................rad---EAGRWPPLRGE.YSL..GDPGSRIAVVTL........A.S........S.L...R-...-....-.....-....-A...P...G......AAIWGPCKTENLGVEKVVGN.LISNSEIRFLLVCGEESK...GHLPGDSIVALHRNGI...dK....D....GR.IVGSRGAIPFIENLSPEAIDRFQRQV.EVIDRIG....LVDEDEIERIVREHR--...........----------------------slsepfpeppmevvkr.........
A0A6A8FKD1_9ARCH/20-165 .....................ilip----------IKDE.YFI..GKGK-TVAICTL........S.S........M.D...LL...Q....T.....I...aRT...E...Gvm..nrILIVGRLLSENKGIDTLIKF.TLKHPELRYIVVCGNDVK...GHQSGQALLSLYRNGV...sR....D....GK.IIGATGPHPFLTHLHA-DIESFRKQI.TIYDLIK....CGELETVKATL------...........----------------------ssfg.....................
Q12VU8_METBU/4-176 .........................KREPAVDWPTLKGE.YDV..GDVKNCVAVITC........G.S........H.I...PS...G....P.....Q....LE...A...G......AAITGPCKTENLGLEKVVAQ.IIGNPNIRFVIITGSEVK...GHITGEAFIMVHKNGV....S....D....NR.IVGATGAIPYVENLTDAAVERLQQQV.EMINMIG....TEDMGQIVAKIKECVAK...........DPGALDVDPMVVEVGEAGGE--gee......................
A0A166A6Y5_9EURY/4-176 .........................KKAPAEGWPIVNGD.YIA..GDPESPVAVTTL........A.S........H.N...ED...I....A.....A....-A...A...G......AAISGPCKTENLGIEKVVAN.VISNPNIRFLILCGAEVQ...GHITGQSFEALHQNGV...dP....D....KRsIVGATGAIPYVENIPDEGIERFQQQL.EIVNLID....VEDAAAIESKVKECIEK...........DPGAFEEEALVISVDDDGGDD-d........................
A0A1Q8QRX9_9FIRM/120-288 ......................qpk---TIRKWPIIEGD.YIV..GNPEASIAICTL........A.D........I.D...LP...N....E.....L....KE...V...Gll..eyAAIIGTLYTENLGIERVIRN.LTANPNIGYLILCGKDSR...GHRAGQAILSLKDNGL...dL....D....NR.IIGALGPRPVLKNITAGEIEAFRKHI.TVINEIG....TQDTSRLTEVVKAYMDK...........PKG-------------------vapilppkvqm..............
L0L1I6_METHD/4-175 .........................KREPAPQWPVLKGE.YEV..GDVKNCVAVITL........G.S........H.L...TG...G....P.....Q....LD...A...G......ACITGPCKTENLGIEKVVVH.IISNPNIRFLIVTGSEVK...GHVTGDAILKMHQNGV....K....D....NR.IVGAVGAIPYIENLTAEAIERFQQQV.ECVNFIG....TEDTNAIVAKIKEYAAK...........DPGAYDAEPMLLKIGEGGEEE-k........................
A0A1D3L1Z6_9EURY/4-174 .........................KKAAAEGWPKIVGD.YVV..GDKESPVAVITL........G.S........H.M...GD...S....L.....I....-E...A...G......AGITGSLHTENLGIEKVVSN.VISNPNIRFLVVCGAEVQ...GHITGQTIKSLYENGF....D....E....KKrIVGSIGAIPYLDNLTEEAIERFRKQV.QLIDLVD....VEDYETIHSKIKECIIN...........DVGAYEEETDIIPIPKQK----dpn......................
A0RXI7_CENSY/1-140 ........................m-----------RGT.VHL..GNPESTVAVCTL........S.S........M.D...LL...D....R.....I....--...A...GselmeeIALAGRLLSENEGIDALIRS.A-NSGNIRTVVLCGREVR...GHLAGHSLLELHKNGI...gP....G....GR.IAGSASPHPVLESG-QAEVDLFRGRV.DIIDAIG....ETGLDDIGR--------...........----------------------lvrsa....................
A0A2U3QE55_9BACT/3-178 .........................KTEVLTDYPPEEGH.YLR..GNDFSPVAVAVIliydydkiP.K........E.I...EQ...-....-.....LvrvgVE...S...G......AALSGTIQTENIGIEKMVCN.VIGNPNIRYLVVTGPESP...GHSTGEAITAMVRNGI....D....G....RKrIIGSGSPTPYLFNLPLEYIERFRKQIkEVVNLLN....RGTPDLVRNAVWSCYQE...........NPTQFED---------------ytlydig..................
Q2W818_MAGSA/105-263 ......................fei----REGWPPVPGD.YFVlcHGADCTVAVSTL........G.D........V.A...LA...A....R.....I....AD...L...Kp...paLCMVGKTETENIGIDKVVRN.VAANPDITTLILVGQDPP...GHQPGRTLLALAENGV...dE....A....MR.VIGSPGKRPILRNVTPDEVATFRQRV.QIIDLIG....EIDPGRIIAAIEQH---...........----------------------ntpapqk..................
A0A4E0QC44_9EURY/53-191 ..............tpesgklclqn--------------.---..------------........-.-........-.-...--...-....-.....-....--...-...-......YSICGTCFTENFGIQKVIVN.VLSNLRINCLIVCGKESK...-HLAGQSIMALVENGV....S....TmggyKK.IIGSKGVIPCLDEIPMTAINRFIREI.EVVDLID....VTNPEIIQKAIDSCKGK...........ER--------------------nrestysmpeinens..........
M7TUS0_9ARCH/5-170 .................kmkneyyp----------WGGE.FTA..CSHNNCVAVVLL........N.T........D.Y...TP...S....N.....N....--...-...-......VAIYGPLKTENIGIEKIVAN.VISNPHIRYLVVCGEDIQ...GHRPGSSLIDLQKNGV...dD....Q....HK.IIEAPGAIPYIENLNPEAIERFRAQI.EVVDLLG....IKDKYKIDKVINDLTTK...........SVSSFGKPYIAIRIKPE-----atvt.....................
MTRA_METMS/4-176 .........................KREPAAGWPILKGE.YDV..GDPENCVAVITL........G.S........H.L...DG...G....P.....M....LE...A...G......ASITGPCKTENLGLEKVVSH.IIANPNIRYLVVTGSEVK...GHITGEAFIMLHKNGV....S....D....NR.IVNASGAIPYVENLTEEAVQRYQEQI.ECIDLIG....TEDMGTISSKIKELAAK...........DPDAFDADPLVIEVGGEAEEEEe........................
A0A0X3BN73_9EURY/4-112 .........................KKSPASGWPIVQGD.FHT..GDAQSCVGVVTM........G.S........H.L...DE...Q....G.....I....CD...A...G......AAIAGSCKTENLGIEKIIAN.VISNPNIRFILCCGTEVK...GHLSGQSFMALHAGGC...lR....-....--.--------------------------.-------....-----------------...........----------------------redrrgrgcdp..............
A0A0S2TEW1_9GAMM/98-273 ......................pel----REGWPPLPGD.YQV..VRMQAPVAVCTL........N.S........D.H...LV...A....E.....L....VA...S...Gv...edLSLVGTLHTENLGIEHLIRN.TLANPHIRFLVLCGEDTQkaiGHLPGQSLISLFHHGV...nE....K....MR.IIGANGKRPLLKNLDVKHVEAFRRQV.QLVECIG....KTDIPTVLKKISEAAAN...........NPGPFAGAP-------------edilpipieaa..............
A0A498GZI2_9EURY/4-175 .........................KKSPASGWPVVQGD.FHT..GDPQSCVAVVTM........G.S........H.L...DE...Q....A.....I....CN...A...G......AAIAGSCKTENLGLEKIIAN.IISNPNIRFVLNCGTEVK...GHLSGQSFMALHKDGI....S....G....GK.IVGAQGAIPFIENLDDAAIKRFQEQI.EMVDIME....SEDMGAISAKIKELTAR...........DPGAFGADPMIIEVKEAGGAE-e........................
A0A0J1FHJ2_9FIRM/118-282 ......................iqq---NIDKWPVVEGN.YQV..GRQNSKVAVCTL........A.D........S.D...LL...E....E.....I....EH...A...Gll..eqVAIVGTLATENLGIERLIRN.IVTNPSIRFLILCGKDSR...GHKAGQAVLSLKSSGI....N....E....QRqILGAVGPRPILKNLSQVELKAFANYV.TVIDEIG....THDIDRLRNVINTCNAQ...........PEG-------------------selilap..................
A0A1A9I7U7_9BACT/41-198 .....................knis----GNRWPPYPGN.YQI..IHPQGQIALCTL........T.S........DeL...IP...V....A.....T....LP...E...N......VAITGTLMTPNLGIERMILN.ILSNPNIRHLILCGKESP...VFKAGQAIECLFSYRV...dH....E....KR.IINAEGHFPVLMNLSEENISRFLKQT.RLISIKN....EKRTEVIQQKINELALK...........----------------------tepyhk...................
A0A498GYL0_9EURY/4-175 .........................KKSPASGWPVVQGD.FHT..GDPQSCVAVVTM........G.S........H.L...DE...Q....A.....I....CN...A...G......AAIAGSCKTENLGLEKIIAN.IISNPNIRFVLNCGTEVK...GHLSGQSFMALHKDGV....S....G....GK.IVGAQGAIPFIENLDDAAIKRLQEQV.EMVDIME....SEDMGAISAKIKELTAR...........DPGAFGAEPMIIEVKEAGGAE-m........................
A0A483CVS8_9EURY/4-175 .........................KTSPASGWPLIKGD.FHS..GDANSCVAVVTM........G.S........H.L...DE...Q....A.....I....CD...A...G......AALCGSCKTENLGLEKVIAN.VISNPNIRFVITCGTEVK...GHLSGQTLIALHANGV....E....G....GK.VVGSKGAIPFIENLDDSAIKRFQAQV.ELVDIME....AEDLGAIKAKINELAGK...........DPGAFGEPPMVIEVKEAEGG--ae.......................
A0A8J7W6P9_9EURY/4-175 .........................KKSPASGWPIAQGD.FHS..GDANSCVAVVTM........G.S........H.L...DE...A....G.....I....CA...S...G......AALCGSCKTENLGLEKIIAN.IISNPNIRFVLLCGTEVK...GHLSGQSLEALHKSGV....S....G....GK.IVGAEGAIPFIENLDDAAIKRFQEQV.ELANIME....TEDLGQIKAKISELTGR...........DPGAFAADPMVIEVKEAGG---ggh......................
A2STR4_METLZ/4-175 .........................KKSPAGGWPIIQGD.YHT..GDANSPVAVITM........G.S........H.L...DE...T....A.....I....CV...A...G......AALAGSCKTENLGIEKIVAN.VISNPNIRFVLLCGTEVK...GHLSGQSIEAMHKNGV....E....G....GK.IVGSTGAIPFLENLGDSDIKRFQEQV.ELINIME....TEDLNVIAAKINELKAR...........DPGAFGADPVVIQLSDDDS---sgg......................
L0KYT2_METHD/8-174 .....................sidm-----NGWPLTDGD.YVI..GDPDSPVAVVTL........A.S........D.Y...KK...L....G.....L....--...H...N......YAICGTCFTENFGIQKVIVN.ILSNPKISCLIVCGKES-...SHFAGQSILALVENGV....S....TlggyKK.IIGSNGVIPYLDEIPLAAINRFIREI.EVIDLIG....TTDQEIIQEAIDSYRGK...........E---------------------rseapkylmseidens.........
E1RDW7_METP4/4-175 .........................KKSPASGWPKIQGD.YHS..GDANSCVVVVTM........G.S........H.L...DE...Q....G.....V....CD...A...G......AALCGSCKTENLGLEKIVAN.VVANPNIRFLITCGTEVK...GHLSGQCLKALHTGGV....E....G....GK.IVGAKGAIPFIENLDDAAIKRFQEQV.EVIDIME....TEDLGAIKAKVQDCISK...........DPGAFAGDAMVIEVKESEGG--se.......................
A0A315XLQ9_9EURY/4-175 .........................KKAPADGWPVISGD.YIV..GDPESPVAVTTL........A.S........H.I...EA...E....L.....S....--...-...G......AAIAGPCKTENLGIEKVVAN.IISNPNIRFLILAGAEVQ...GHITGQSIQALYDNGA...dP....D....KKkIIGATGAIPFVENVPLDGIERFQQQL.EIVDLID....TEDIGAIQSKINECVEK...........DPGAFEEEAMVISVDDDGGEEEe........................
F7XKL5_METZD/1-167 .......................me--HVANDWPPAKGD.YVI..GSIDSRIAVVTL........A.S........S.I...EP...T....E.....K....--...-...-......AAIWGTCKTENLGVEKVVIN.IISNSNIRYLLLCGGESR...GHLSGKSLIALHNNGI...dE....N....GR.IIGSDGAIPFIENIPENAIIRFQEQV.DLIDYTG....LTDKKEIYELVD-VYSN...........KNEAYAEEPFVILTGK------rkksc....................
A0A328S3T3_9EURY/4-177 .........................KKEIVEGWPLETGD.YSV..GNPESCVAVVTL........G.S........K.M...ND...E....M.....V....-E...A...G......AAIAGPLHTENLGIEKLVTN.IVSNPNLRFLIVCGSEVQ...GHITGETVEALYDNGI...dP....E....TKsIIGSPGAIPFVENLPIEAVERFQKQL.TIISMIN....NENVDEITEKIGECTEN...........DPGAYEEDAMIVQLNEKDEDEEe........................
A0A8J7NAQ9_9ARCH/1-162 ........................m------EWPIEPGE.YEV..CDPKKSIAVVTL........A.D........D.I...EV...P....R.....-....--...D...K......IAKFGKVRTENLGLERIIVN.TISNPCIRYLVICGEEIK...GHRSGASLVALWKNGL...dK....N....RK.IIGAPGALPVIQNLPRNFVDRFREQV.EVVDLIG....ETDAKRIEKSINSLKKK...........DA--FK----------------geglnfkdyavkeeh..........
MTRA_METMP/4-178 .........................KKAPAAGWPVANGE.YVV..GNPESCVAVVTL........G.S........H.G...LD...Q....A.....A....ID...A...G......AAISGPCHTENLGIEKVVAN.YISNPNIRFMVITGSEVQ...GHITGQCIKALYENGI...gD....D....GG.IIGAKGAIPFMENVGTEPVGRLQSQIvECIDLID....VEDTGKISDAIKNCISK...........DPGAFEEEPMVIELEGGA----aaage....................
MTRA_METJA/4-179 .........................KREPAPGWPIVSGE.YVV..GNPESCVGVVTL........G.S........H.G...LE...Q....A.....C....ID...A...G......AAIAGPCHTENLGIEKVVAN.YISNPNIRFMILCGSEVQ...GHITGQCFKALWENGI...gD....D....GG.IIGAKGAIPFLENVNKEAVERFRRQIvEVVDLID....CEDIGKITQAIKECLSK...........DPGAIDEDPFIIELEGGKG---ggeee....................
A0A2V2N3V7_9EURY/4-175 .........................KKSPASGWPIVQGD.FHT..GDPQSPVAVVTM........G.S........H.L...DE...Q....A.....I....CN...A...G......AAIAGSCKTENLGLEKVIAN.IISNPNIRYVLTCGTEVK...GHLSGQSLIALHQSGI....T....G....GK.IVGSKGAIPFIENLSAENIKRFQDQV.EMVDIME....AEDIGAISAKINELKAK...........DPGAFDAEAMIVEIKDESG---gsg......................
R9SLV8_9EURY/4-176 .........................KKSPADGWPLISGE.YEV..GDPESPVAATTL........A.S........E.L...AG...D....I.....V....-G...A...G......AAIAGTCHTENLGVEKVVAN.TISNPNIRFLIVCGAEVQ...GHITGQCFEALHANGCd..pE....K....KK.VNGAIGAIPFVDNLPLEAVERFQNQV.ELISMID....NEDVGAITAKVKECIEK...........DPGAIEEEAMVIDVSEGGEAE-e........................
U6EEN6_9EURY/4-177 .........................KKSPAEGWPVINGD.YVV..GDPESPVAATTL........A.S........H.I...EQ...I....A.....V....-D...A...G......AAISGPCKTENLGIEKMIAN.LISNPNIRFLILTGSEVQ...GHITGQSIESLHKNGV...dP....E....KRkIVGATGAIPFIENIPDEGIERFQQQM.EIVSIID....VEDAATIQSKVKECIDK...........DPGAFEEEAMVIKVEEGEGDE-ee.......................
MTRA_METMA/4-175 .........................KREPAPGWPILKGE.YEV..GDVKNSVLVITC........G.S........H.L...PG...K....P.....I....LD...A...G......AACTGSCKTENLGIEKVVAH.IISNPNIRYLLVTGSEVK...GHITGQSMMSLHANGV....K....E....NR.IAGALGAIPYVENLNAAAVARFQEQV.QVVNLLD....TEDMGAITSKVRELASK...........DPGAFDADPLVVEISEEGEEEE.........................
H1YXH4_9EURY/4-175 .........................KRAPASGWPKIQGD.YHA..GNAESPVAVVTV........G.S........H.L...DE...Q....G.....I....CD...A...G......AAICGSCKTENLGLEKIVAN.VVANPNIRFMVTCGTEVK...GHLSGQCLHALHANGL....E....G....GK.IVGAKGAIPFIENLTDESIQRFRDQI.EMVDIME....SEDMGAIKAKIDELTAR...........DPGAFDGEPIVLEVKEDDGG--aa.......................
D1YWC8_METPS/5-159 ......................gdk----------IEKT.YKY..GDASSPVAVATL........A.S........D.Y...EK...F....D.....L....--...K...G......YAILGSVFTENFGVQMAIAN.MLKDQNIGYLILCGQES-...AHLSGHAFVTLHENGVvqigT....S....RR.IIGCKSPLPFIDEIPMGAIDEYQENI.KLIDMIG....IEDTKLIQAKIDECTEE...........----------------------skkrsyrrkpf..............
A0A6A7LBE6_9ARCH/52-196 ....................pirls--------------.YAM..GNGE-TIAICTL........S.D........M.S...LL...K....E.....I....VS...R...Ndi.mrkLFLVGRLLSENRGIDNVLET.VHNYPHLRYLILCGREGK...GHLPGQALISLYNHGT...rK....D....GY.IVGARGSNPKLKS-TKEVISSFRTNI.EIVDMIG....SRDILQLELLIDK----...........----------------------lsgq.....................
A0A328PA09_9EURY/4-177 .........................KKAPAEGWPVVNGD.YVV..GDPESPVAAVTL........A.S........H.I...ED...V....P.....H....-E...A...G......AAIAGPCKTENIGIEKVIAN.VISNPNIRFLVLCGSEVQ...GHIVGQSLAALYENGVd..pE....Q....NRkIIGADGAIPYIENIPDEGIERFQKQV.ELVNMID....VEDPEQIKAKVKECIEK...........DPGAFEEEAMVIEVEEEAEEE-v........................
MTRA1_METTH/4-176 .........................KKSPAEGWPVVNGD.YIV..GDPESPVAATTL........A.S........H.I...ED...V....P.....V....-E...A...G......AAIAGPCKTENLGIEKMIAN.LISNPNIRFLILCGSEVQ...GHITGQSIEALHQNGV...dP....D....KRnIIGATGAIPYIENIPDEGIERFQKQL.EIVNLID....VEDADAIKAKVKECIEK...........DPGAFEEEAMVIKVEEGGEEEE.........................
A0A1D2WAN0_9EURY/4-174 .........................KKSPAEGWPVINGD.YVV..GDPESPVAATTL........G.S........H.N...EQ...I....P.....V....-D...A...G......AAIAGPCKTENLGIEKMVAN.LISNPNIRFLILCGSEVQ...GHITGQSIEALHANGL....D....E....KRkISGATGAIPFIENIPDEGLERFQQQM.EIVSMID....VEDAGQIQGKVKECIEK...........DPGAYEEEPIAIRLDELE----kil......................
#=GC seq_cons ...........................tsspsWPhlpG-.Yhs..GcspSsVAVsTL........u.S........+.h...pp...t....s.....l.....p...u...G......AAIsGss+TENLGIEKllsN.lISNPNIRalllCGsEVp...GHloGQolhALacNGl....c....c....s+.IlGApGAIPalENlsp-ulcRFppQl.EllDhls....sEDhspIpspIc-hht+...........DPGAhtttshhlph.t......t........................
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