#=GF ID MycE_N
#=GF AC PF17843.5
#=GF DE MycE methyltransferase N-terminal
#=GF AU El-Gebali S;0000-0003-1378-5495
#=GF SE ECOD:EUF00022
#=GF GA 27.30 27.30;
#=GF TC 28.90 29.50;
#=GF NC 27.10 25.40;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP Domain
#=GF WK Sterol_carrier_protein
#=GF CL CL0311
#=GF RN [1]
#=GF RM 21884704
#=GF RT A new structural form in the SAM/metal-dependent
#=GF RT omethyltransferase family: MycE from the mycinamicin
#=GF RT biosynthetic pathway.
#=GF RA Akey DL, Li S, Konwerski JR, Confer LA, Bernard SM, Anzai Y,
#=GF RA Kato F, Sherman DH, Smith JL;
#=GF RL J Mol Biol. 2011;413:438-450.
#=GF DR INTERPRO; IPR040800;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC This is the N-terminal domain found in MycE from the mycinamicin
#=GF CC biosynthetic pathway. MycE is a tetramer of a two-domain
#=GF CC polypeptide, comprising a C-terminal catalytic MT domain and an
#=GF CC N-terminal auxiliary domain, which is important for quaternary
#=GF CC assembly and for substrate binding [1].
#=GF SQ 70
#=GS B4VAJ3_9ACTN/10-119 AC B4VAJ3.1
#=GS A0A495W745_9PSEU/15-124 AC A0A495W745.1
#=GS A0A0X3WL99_9ACTN/2-117 AC A0A0X3WL99.1
#=GS A0A3N4ZGC1_9ACTN/7-114 AC A0A3N4ZGC1.1
#=GS A0A263D5G8_9PSEU/7-118 AC A0A263D5G8.1
#=GS A0A495W1R5_9PSEU/23-130 AC A0A495W1R5.1
#=GS A0A2G5J425_9ACTN/16-132 AC A0A2G5J425.1
#=GS A0A7X6L9Z9_9NOCA/10-118 AC A0A7X6L9Z9.1
#=GS A0A0L8L2D8_9ACTN/10-118 AC A0A0L8L2D8.1
#=GS A0A8J4E3T7_9ACTN/15-124 AC A0A8J4E3T7.1
#=GS A0A2W2GD89_9ACTN/11-119 AC A0A2W2GD89.1
#=GS A0A7K0BU56_9ACTN/8-117 AC A0A7K0BU56.1
#=GS A0A222VM03_9PSEU/1-106 AC A0A222VM03.1
#=GS A0A2S9Q1H7_9ACTN/10-117 AC A0A2S9Q1H7.1
#=GS G0FY75_AMYMS/11-120 AC G0FY75.1
#=GS A0A2N3Y621_SACSN/12-118 AC A0A2N3Y621.1
#=GS A0A7W9HJY4_9PSEU/5-115 AC A0A7W9HJY4.1
#=GS A0A370HW29_9NOCA/5-114 AC A0A370HW29.1
#=GS A0A6H0CX69_9ACTN/9-117 AC A0A6H0CX69.1
#=GS A0A365H0V9_9ACTN/9-117 AC A0A365H0V9.1
#=GS W7ISL0_9PSEU/40-155 AC W7ISL0.1
#=GS A0A7W9LGS9_9ACTN/10-118 AC A0A7W9LGS9.1
#=GS A0A3R7HZ30_9ACTN/1-66 AC A0A3R7HZ30.1
#=GS A0A542DJF3_AMYCI/10-122 AC A0A542DJF3.1
#=GS A0A7G1KIV1_9NOCA/7-116 AC A0A7G1KIV1.1
#=GS A0A840Q8T4_9PSEU/14-122 AC A0A840Q8T4.1
#=GS D6X7X4_STRE2/11-122 AC D6X7X4.1
#=GS A0A8J4E3R3_9ACTN/20-129 AC A0A8J4E3R3.1
#=GS A0A561WAK7_ACTTI/20-138 AC A0A561WAK7.1
#=GS R4LTM4_9ACTN/20-135 AC R4LTM4.1
#=GS A0A1T3NWK7_9ACTN/8-115 AC A0A1T3NWK7.1
#=GS A0A5B2X0G2_9PSEU/10-119 AC A0A5B2X0G2.1
#=GS A0A366DJF4_9NOCA/1-88 AC A0A366DJF4.1
#=GS A0A2T0K8M3_9ACTN/12-115 AC A0A2T0K8M3.1
#=GS A0A4R4RWY2_9ACTN/23-131 AC A0A4R4RWY2.1
#=GS A0A1Q4WAH4_9ACTN/12-120 AC A0A1Q4WAH4.1
#=GS A0A0L8L212_9ACTN/8-116 AC A0A0L8L212.1
#=GS A0A3S9PE10_STRLT/10-120 AC A0A3S9PE10.1
#=GS A0A117RXK3_9ACTN/6-120 AC A0A117RXK3.1
#=GS A0A5B2XHD3_9PSEU/4-110 AC A0A5B2XHD3.1
#=GS A0A7K1KVL8_9ACTN/8-117 AC A0A7K1KVL8.1
#=GS A0A3E0GZ78_9PSEU/6-117 AC A0A3E0GZ78.1
#=GS A0A7W7T4W2_9PSEU/6-114 AC A0A7W7T4W2.1
#=GS Q9ALN2_SACSN/10-119 AC Q9ALN2.1
#=GS A0A3E0HER4_9PSEU/6-105 AC A0A3E0HER4.1
#=GS A0A1H5TSI8_9ACTN/9-117 AC A0A1H5TSI8.1
#=GS A0A7W9HJL3_9PSEU/10-117 AC A0A7W9HJL3.1
#=GS A0A3N4Z1M7_9ACTN/9-116 AC A0A3N4Z1M7.1
#=GS A0A6G2VX54_9ACTN/22-134 AC A0A6G2VX54.1
#=GS A0A7X0IGS2_9ACTN/8-115 AC A0A7X0IGS2.1
#=GS A0A1Q4WAP2_9ACTN/1-108 AC A0A1Q4WAP2.1
#=GS A0A5N0VMV9_9PSEU/5-111 AC A0A5N0VMV9.1
#=GS A0A1J4Q6Q2_9ACTN/6-116 AC A0A1J4Q6Q2.1
#=GS A0A7H1BK99_9ACTN/10-121 AC A0A7H1BK99.1
#=GS K0EQJ5_NOCBR/12-121 AC K0EQJ5.1
#=GS A0A2P2GUI0_9ACTN/10-117 AC A0A2P2GUI0.1
#=GS A0A7W7CI68_9PSEU/5-115 AC A0A7W7CI68.1
#=GS A0A1T3P792_9ACTN/6-114 AC A0A1T3P792.1
#=GS A0A2S4YM54_9ACTN/8-118 AC A0A2S4YM54.1
#=GS A0A0G3IT25_9MYCO/8-117 AC A0A0G3IT25.1
#=GS A0A6G9YGL3_9NOCA/10-119 AC A0A6G9YGL3.1
#=GS A0A6G2VYV1_9ACTN/5-120 AC A0A6G2VYV1.1
#=GS A0A318JXL5_9NOCA/1-110 AC A0A318JXL5.1
#=GS A0A7Y7B599_STRMO/9-120 AC A0A7Y7B599.1
#=GS W7J2P5_9PSEU/12-121 AC W7J2P5.1
#=GS A0A840QJV9_9PSEU/9-116 AC A0A840QJV9.1
#=GS A0A318LVD0_9PSEU/11-119 AC A0A318LVD0.1
#=GS A0A5Q0GY58_SACSY/7-117 AC A0A5Q0GY58.1
#=GS A0A7K0D1A1_9NOCA/10-117 AC A0A7K0D1A1.1
#=GS A0A562I249_MICOL/4-107 AC A0A562I249.1
B4VAJ3_9ACTN/10-119 ..............IREIIRAAGGHDADLKDLAARYAPA...DIVRVLLDEITTRCPA.PVNDV....-PVLVELAVR..A..........GDQ.L..F..PTYLYVLKGGPVR..LATKDEAFVAM.....RVEYELGELARELFGPVRENVTGVR........
A0A495W745_9PSEU/15-124 .............t-SRVIRAAGGHEAELTALAGELGLG...GLVPVLLSEVLFRADP.APVRV....-PSLVELVVE..H..........DGQ.R..S..SHVLRVAADQPPT..PSDEPPDQAVM.....RVEYRLTDLARELFGPPRDRQSGVR........
A0A0X3WL99_9ACTN/2-117 ..............THALIAAADRGHADVAATVEKAGLR...GVAAVLINEMLFRAHL.DELAAldgaGEGSLVITLT..H..........GGE.E..T..SVLVSVGPGG---..VEIGKAARPAEip.ptVIVQGVCEAALALYGPPERVSSAG-p.......
A0A3N4ZGC1_9ACTN/7-114 .............a-RALIDSAGGTPSHTREEIERIGVD...EAAAFLAAELAGRVET.RALSG....-SADIQLVF-..E..........GSR.T..M..PWVLNVSRSGVS-..HRSGELQDPEA.....VVTQDLTEAARSLFGPSGEQSAATR........
A0A263D5G8_9PSEU/7-118 ..............ILRLLDATAAGLEPGADTLDELGPD...RVARILLDEIVDRARL.DTLGTf..aDTVVVEFRLA..C..........HTG.A..A..IVFLSLGDGGCT-..VSTEPPRAADV.....VVGQQLGEVCLAVFGPAESVSASTR........
A0A495W1R5_9PSEU/23-130 .............a-EELIAAAAAGGRALDGVLRTRGAR...ACAEVLLGEIRDRLRR.VTPPA....DGTRLRVSLH..H..........GEE.R..V..GEVLRFGPAG---..VRPGPAAEVAD....aEVAWDVVELAALLYGNLDPRAA---hg......
A0A2G5J425_9ACTN/16-132 ..............VETLVTAVGAGPRRLAAAVGEIGFE...RSAAVAVREIPLRWDP.PWQAA....-PATTHLRIR..HdgrphdgqspGGQ.S..V..DYAVQAYDGRVQ-..VAPGRPSQTTA.....TVTYEVCELLRSLFGPRDG------lrpa....
A0A7X6L9Z9_9NOCA/10-118 ............aa--HLISVADGVYEETAARIGEIGTE...AVADAVLKEIAWRANY.GSRPG....QPVTAVFELT..H..........EGK.Q..L..DYLLTLGAEEPA-..IAPGSLEDPWL.....VVRQDLVELLRAVYGPPDA------algtr...
A0A0L8L2D8_9ACTN/10-118 .............l-ADLITLADRPPGEADAAIADLGAS...TVAEALLAEVSSRARL.LSDPP....EKVAVQFDLG..F..........GGE.R..L..HYLLALGPGTRE-..VEPGHDPLAPV.....TYRQDLSELLRAVFSPGRHE-----gtre....
A0A8J4E3T7_9ACTN/15-124 ..............IERLLAAADGTPDETADRLAGEDPD...AVAVTTLAEVMTRVAL.DEVAG....APVAVQVDLG..G..........PGG.R..L..GYVVTVGDPAAK-..VAPGWIADPWV.....RLRQDLTEFVRAVFGPAVPPAGAT-r.......
A0A2W2GD89_9ACTN/11-119 ............aa--ALIAVADGDPAALTGTIERAGAG...EVAALLADEMAFRCGV.PAHGH....-EVGLRLDLL..H..........EGK.R..W..SRVLRCVPYRGVV..VEPAGAVPVAA.....TLTARLEETARGLFGPGAARRA---gw......
A0A7K0BU56_9ACTN/8-117 ............ae--LLILAAGGRETELAAAIEEVGAK...AVCSLAVEELVFRCRL.PSNKT....-HVHVRLDLL..H..........GGE.R..F..THTIGVQAGRPVT..LVEGEPDTAIF.....LLEFELAELVRSLYGPLRERR----pgth....
A0A222VM03_9PSEU/1-106 .............m-EKLLSIADGVEEDTRARLDDVD--...--ASLVLREMVSRAAL.LVGPS....MPVTIQFDLA..A..........ADK.K..L..GYLVTIGPGESK-..VESGWSQDAPA.....RIRQDLAELVRSVFGPVGGEHATR-e.......
A0A2S9Q1H7_9ACTN/10-117 ..............VRALILAAEG---DAEQAVREVGAE...RTAALLVGELVDRADL.DEVPGl.dqTPITVAFELA..F..........DGG.A..V..VHHAVAGKTA--E..HHPGAPAAAHA.....TIEVGLLELLRAVYGNWRA------pgcqn...
G0FY75_AMYMS/11-120 ..............IEALIRAASGRPDEIRARLDALGLA...RVAELAVAEWTLRLDP.PANPL....-EIHIGLSVS..D..........GRE.S..A..DHTWVLRAGEPVR..VLPGLHPACDV.....RLRYDAEDLITELWGPSRGRSSAAR........
A0A2N3Y621_SACSN/12-118 ..............VERLLLAAGAGPAKLQEAVQVAGLD...AVADAIVDELVVRCDP.LSLDE....-SVRIGLEIT..S..........GAQ.L..V..RRTVELDHAGL--..-RLAAVAEAAA.....VLRFDAVDLLEGLFGPVDGRRHNS-r.......
A0A7W9HJY4_9PSEU/5-115 .............e-EQLLDIAERSPGAVSDWLDDLGEAgavDVAAATLAEIAARATL.LEPPD....REVPVQLDLG..L..........GAR.R..I..PFVLVLGPEPK--..VVPGSDPTSEL.....LVRQDLAELIGLVFGPAPAT-----atre....
A0A370HW29_9NOCA/5-114 .............l-DRLLRAGTASDADISSLIKDEGVD...AVLTALIEEALFRASV.PTNPE....-PVHIALDIT..H..........EAE.T..R..RVVLHCVGGRRI-..-TRSDDQAPQEi..crELGMSLTHLIRRLYGRPGQRR----tgd.....
A0A6H0CX69_9ACTN/9-117 ..............LEAILRCAGGDERFLLNTVEEWGAA...EITAALVDELLFRCEI.PQVGG....-EAFIGLDVL..H..........GAD.R..I..SHVLQVTDGKPVT..SAEPAGQELGA.....VLEFTLSDLLRELFGPASGRTAG--a.......
A0A365H0V9_9ACTN/9-117 ..............IQRLIRAGTGSDEEIAVLLDDVGLP...RFVQALTEEIVFRCPE.PANTM....-PIDVALEVT..Y..........GKE.S..H..TSVLRVAQGAAVT..VVEEESATVWS.....KIGISAADLLRRLFGPADSRR----tgd.....
W7ISL0_9PSEU/40-155 ..............IRDLLAATASADGDVTAAIDGLGVE...RTARVLVEEVVFRARL.GDTGVr.agEAVSVVLALA..H..........RGR.E..L..ATTVCVGPGGIE-..VRDGHTPGTAPp..paVIAQDLVEVARALYGPRELVTAATR........
A0A7W9LGS9_9ACTN/10-118 vaslveagdldggh---------------ERVIAEIGPE...KVAGVLVAELLSRCGP.AAEES....---VVRLELTgpD..........ADG.TgpV.pGIAFDIGFGPEGA.aVVEGERSGADV.....RITYPIADLARALYGTR--------atgl....
A0A3R7HZ30_9ACTN/1-66 .............m-------------------------...----------------.-----....-PVLVELAVR..S..........GDA.L..V..PRRLAVAQGAPVR.rAAPDDDGFVAM.....RVEYELDELVRELFGPCRERAAGTR........
A0A542DJF3_AMYCI/10-122 .............l-RSLILAAGGSAEQIASTVTRVGPD...RVAAILVDELVHRAEL.GTIPQl.aeRPITVSFDFS..F..........EGK.V..F..AHAVT-SSGTRTE..PAPAGEEAPHA.....RVELDLVQVNRAVFGPPGARHGT--dr......
A0A7G1KIV1_9NOCA/7-116 .............a-ERLILAAGCRHADLVAAIEDIGAQ...AVGALVVDELVFRCRP.PTNEY....-RMVIELRLR..H..........GEK.V..F..AHSLAVQSGQPVG..VTAGPDETAIA.....RLEFELADLVAELYGPPRERAAGT-h.......
A0A840Q8T4_9PSEU/14-122 ..............LERLIRAADARDDELWKTITGIGVD...RVARLLVEEVAFRADP.ATVHR....-TFDVGLEITgeE..........AAE.P..I..RYILQVLPSGQIE..FFEGTSPTTVH.....VIGYRCADLARDIFGRAR-------itrp....
D6X7X4_STRE2/11-122 ..............ILKLILAAEGGTEQIDAAIRAVGAE...RTAAILADELVNRADL.HEIPGp.gtAGVDIQLALA..F..........DGG.T..V..HHVVRVGKSAE--..HEAGRVDAPHA.....TLESDLAELLRSVLGPWRGVEAQT-l.......
A0A8J4E3R3_9ACTN/20-129 ..............VERLVRAADGRDAELANVVDALGAG...EVAALAVEELVFRCAP.PGNPV....-PVDVQLDLV..H..........GVR.R..L..VYTLSVRAGEAVT..ATPEGSGTACA.....RLEFELTQLLRLLYGPADGRTTGT-h.......
A0A561WAK7_ACTTI/20-138 ..............VERLLAATASRDDDVDAVIDDLGAV...EVADVVVAELLFRACV.EDLVPaagdDGAAVTVVFS..H..........RGR.D..I..TTFLAVTSGGVR-..VVPGELGAPYEeslspSLTQELSETVRALYGPLADVSATTR........
R4LTM4_9ACTN/20-135 ..............VARLLAATAAGDDDVAAVIDDLGAG...EVADVVLAELLFRACV.EDLVPaagaDGASVTVVFS..H..........RGH.D..F..STSVAVTAGGVR-..VVPGELGAPHEn...pALTQELSEAVRALYGPLADVSATTR........
A0A1T3NWK7_9ACTN/8-115 .............l-DRVVQAGTAPDAEIFAVVEDAGLG...AVVGVLVEEILFRCDA.PINVM....-PVDIALDVT..H..........ESE.R..H..RTVFRMVRDRPIA..ILDGEEPVIRR.....ELRMNVVDLVRRLYGRAD-------hprtg...
A0A5B2X0G2_9PSEU/10-119 .............v-ADLLDIAERSDAEASAAIAGLDPE...RVAVAVLREIAARARL.RPEPP....DPVTVALDLG..F..........ADR.R..L..GFAITLGAGKAE-..VAVGGDAEAPV.....LIRQNLVELLRAVFGPAGRHDAS--re......
A0A366DJF4_9NOCA/1-88 ..............---------------------MGAD...VAAEAVLREIAWRARY.GDQPS....QSVQVAFALE..H..........EAK.Q..L..DYLMTLGADDPA-..ITAGTLEDPWL.....SVRQDLVELVRAVYGGADAECA---tr......
A0A2T0K8M3_9ACTN/12-115 ....aeiiapgpap--------------LPHAVKRFGAE...SCGDALVDELISRCDP.PHIDT....-PVDLHLALT..T..........PDQ.G..L..DYHVRFTDEAVE-..VIRQEPESPWA.....RFELTLGGLADLLFGDPPTAA----aad.....
A0A4R4RWY2_9ACTN/23-131 ..............TRRLVHAGTASDDQIQALVDAAGLD...AVARALGEEICFRCPE.PVNPM....-PIDVALDVG..H..........RDQ.E..R..RLVLHVVRDRPVR..LREDRPGTIWS.....QVGIGVTDLVRRLYGRGDRR-----mtgd....
A0A1Q4WAH4_9ACTN/12-120 ...........iec----LRLAGDDTRSLHSVVHSFELA...DLTAVLVDEILFRCDP.PGNAD....-PVTVVLDVT..R..........GEE.R..V..STSFLVQAGRPV-..GLHGADGPAAL....fRIEYDVLDLARELFGPFAP------ggpanr..
A0A0L8L212_9ACTN/8-116 .............l-DRVIQAGTASDAEMSGLLKDAGLE...AVVRVLVDEVLFRCDE.PVNAI....-PVDIALDIT..H..........ETE.R..R..RVVFRIVRDRPME..IVGSEESVIRR.....ELRMDVKDLLRRLFGHADHR-----rtgd....
A0A3S9PE10_STRLT/10-120 .............l-RDIIGAAGGHDAALKDLVDRHSPA...DITRVLLNEITSRCPA.PVNDA....-PVLVELAVH..T..........DGTaP..A..PHYLYVAKGGPVR..PAGRDEAFIAM.....RVEYDLADLVRELFGPVRERGAGVR........
A0A117RXK3_9ACTN/6-120 .............t-GKLIAAAGGTERDIGDALRAVGPE...RAVQLLADELIHRADL.EDLPH....AEAVVRFACH..L..........GER.T..V..NHLVHVSKGSARH.lADAGESERATAp..dvTVRYDTPELVRAVFGPTSARTSATR........
A0A5B2XHD3_9PSEU/4-110 ..............INQLLDAAETRSSDLAATISAIGFD...SVAELLFQEIRFRARI.DEVAG...aGYADTTLVLV..H..........EGH.K..A..EFTVPAAPDGG--..---PGGDLPSV.....VITQEVGEIVRSLYGPRDLVSAATR........
A0A7K1KVL8_9ACTN/8-117 ............ae--LLILAAGGREAELLAAIEDVGAK...AVSSLAVEELVFRCRL.PSNKT....-HVHIQLDLL..H..........GGE.R..F..THTVGVRAGEPVT..LHEGELDTAVY.....LLEFELAELVRGLYGPLRERRAGT-h.......
A0A3E0GZ78_9PSEU/6-117 .............v-LRLIHAAGLHEAELVATVAELGLA...EVARILIDEVLFRAAV.PHNHY....-PVVVQLTIA..H..........EGR.R..V..DSQLRAVGGKPWEllPVAAADQLVAM.....RIDYEALDLIRAVFGPGEERSV---gyr.....
A0A7W7T4W2_9PSEU/6-114 ..............LERLIEAAGGGERRLAAVTDEFGLA...GLAPLLAGEIAFRATT.AARPG....-GGNVALGVR..H..........RDR.T..E..RFVLTVAADGRVT..AEAGTTDDPAL.....SLDYDLHDLVRLLFGPTRPRAT---gh......
Q9ALN2_SACSN/10-119 ..............VERIILAAGSSAASLADLTTELGLA...RIAPVLIDEILFRAEPaPDIE-....-RTEVAVQIT..H..........RGE.T..V..DFVLTLQSGELIK..AEQRPVGDVPL.....RIGYELTDLIAELFGPGAPRAVGA-r.......
A0A3E0HER4_9PSEU/6-105 ..............LRRLIVAAGGGVADAEIAVKEIGPD...AVVPVLLRELLERADF.GGVDT....-TATVLFELD..D..........---.-..-..-QCWTITAAG---..FAPGRT-DCEV.....TVRQELWDLLRGVFGPAAARTNCTR........
A0A1H5TSI8_9ACTN/9-117 ..............TERLILAGTASDREIAELVDDAGLD...AVVAALVEEILSRCEQ.PVNIK....-AVHIALDVD..H..........GDE.R..R..RVVLRVHRDEPVR..VVDEPAPVVWS.....RLGITVTDLIRRLYGRTDHRR----tgd.....
A0A7W9HJL3_9PSEU/10-117 .............a-RELTRAAGGPARELPAALDGIGLE...DAATVAVAELVARCGV.PINTD....-EASIGVSVA..H..........RGE.R..V..DHVLRLVRGGS--..VRAERSAEQAP....cRLVFELADLVVALYGS---------qpsppvgt
A0A3N4Z1M7_9ACTN/9-116 ...........lta---LPATAGLQQRELLAALDQIGLE...MAAQILIRELLTRCDT.PDNTD....-EARVGFAVE..H..........RDQ.R..T..ERVLVLRKGESVQ..IDEYVSESAPA.....RLTFDLADLVRGVYGPPP-------gpgag...
A0A6G2VX54_9ACTN/22-134 ..............VEQLILAAGGRCESVREVVEDLGAE...RVCALLADEVAFRADI.PVMDLf..dSPLLLRFDIT..H..........GGL.R..A..GHVVEAVHGKPVR..LYPGSDDRAAM.....VVEYDLLDLVDDLFGPARDRRAGRR........
A0A7X0IGS2_9ACTN/8-115 ..............IRRLLSSAGGTEDEIRAVIDEIGEE...CAAAILVDEIAARFDP.PALDR....-EYTLRAEFP..G..........ARQ.V..H..AYTFTVSSAGLT-..AVPADGRPPDA.....LVACDLAALTRAVYGGGRRA-----arae....
A0A1Q4WAP2_9ACTN/1-108 .............m-EPLLRAAA-DEHRLARAVADLGLD...RVAEVVVEELAVRCDP.VPVDG....-AAHLAFELT..S..........GGE.R..A..CRLLTVDRDGLTS..KRDGWQAAPV-.....RITHDAVDLLRGLYGPGTDRRTSR-r.......
A0A5N0VMV9_9PSEU/5-111 ..............IERLIAAGPAPDDAVAALVAELGLD...KVAETLVGEILFRCPP.SENTV....-PVAIALDVT..H..........GAQ.R..C..RTVLRLARDEPI-..-RETGSPDVQM.....VLEFTAADLVRRLFGPTGHRRA---gd......
A0A1J4Q6Q2_9ACTN/6-116 ..............VRELIDAATRTPGEIDAAIDRIGPA...TVAAVLLDELGSRADI.DELTD...yPTIVVEFALS..H..........RGE.T..A..SHTITTDKGRTT-..CAPGRPDAPDA.....VVSQELADLLRGVFGTRGARTNPTR........
A0A7H1BK99_9ACTN/10-121 ..............ILKLILAAEGGAEQIEAAIREVGPE...RTAHILADELVNRADL.HEIPGq.daAPVDIQLALA..F..........DGA.T..V..GHVIRAGKSAE--..HEAGRAEEPHA.....TIEADLAELLRAVLGPWRAPEAQ--vl......
K0EQJ5_NOCBR/12-121 ..............LERLIHVAGAGDDLIAEHIEWMGVE...RTARTLVREVLDRVDL.RGCPP....--IDVLFRLH..A..........GAQ.S..A..DVTVRVAADGSTT.tPSAPSSGAVAA.....TVEQSLPEFVRSVLGPRGAATSATR........
A0A2P2GUI0_9ACTN/10-117 ..............IRRLIRAGAGTDDEIDVLLKDAGLA...EVARVLVEEVVFRCPE.PANTT....-PVEVALDLT..H..........GGE.R..H..GVALRMVRDEPVR..VVAEESARVRS.....RVTFTAAGLIRRLYGPTD-------sprtg...
A0A7W7CI68_9PSEU/5-115 ..............ITRLISAAGGHPADLATAIDEVGPA...RCTEIAADEIAYRLDP.PRLDP...dTRIEVQLRLS..H..........RDT.T..T..DHLVGITDAGAT-..HTQARSANPHA.....TIHQDLGELLRQLLGPREAASAASR........
A0A1T3P792_9ACTN/6-114 .............l-SELITAADLPPADTDAAIAELGAA...AVAEALLSEISARTRL.LPEPI....EKTTVQLDLG..F..........DDK.R..L..HYLFTLGAGTCE-..VEAGRAPRPPA.....TYRQDLSELLRAVFSPGRH------dgtre...
A0A2S4YM54_9ACTN/8-118 ..............IENVISAATAPASEISARVADLGPA...TVAEVALAEVAGRAAL.HGRPA...iEQVGIQFQLA..F..........GSA.R..L..DYVVHLGPEKIA-..IEASSSEDAPV.....TIKQDLVDLLYETFGPAGNHGATR-e.......
A0A0G3IT25_9MYCO/8-117 ..............IETILRAACLPEPDISARVADLGPD...AVARILLEEVACRAGL.LYGPP....DGLVVQCDLG..F..........GGE.R..L..GYLFRLKSGGAS-..VEEGWDADAAA.....TVRQDLIDLLREVFGPVGPHGATR-e.......
A0A6G9YGL3_9NOCA/10-119 ............aa--QLISIADGVYEESAARLGEIGAD...AVAEAVLTEIAWRARA.ANPPT....QPVTAVFELS..Y..........EGK.Q..F..DYLLTLGAEQPA-..VGPGTLADPWL.....VVRQDLVELLRAVYGPPDAVNATR-a.......
A0A6G2VYV1_9ACTN/5-120 .............t-DALIEAADRGRADVAATVEAAGLR...TAAATLINEVLFRAHL.DEPAAaagaGEGSLVITLT..H..........GGQ.E..T..SVLVSVGPTG---..VEIGRAARPAGlp.ptVIIQDVCETALALYGPRERVSSASR........
A0A318JXL5_9NOCA/1-110 .............m-DRLLRAGTAADAEISLLVKEEGVD...AVLDALVDEVLYRASV.PANPE....-PVHIALDVT..H..........DAE.A..R..RVVFRCVGGERI-..VRAEGEAPVEIc...rELGMTLTHLVRRIYGRPDQRR----tgd.....
A0A7Y7B599_STRMO/9-120 ..............IQQLIAGAGDTPRALRRAVDHVGPA...RAAELAVEEIRTRIDV.PVNPH....-EIRVGLRIE..H..........DGY.D..TatDRTLTLTAGRPVR..VDEGMQESCEV.....RIVYRLKDLVRELWGPDLARTAGTR........
W7J2P5_9PSEU/12-121 ..............LERLIRAAD-DDERLRAVVAELPLA...ETARLLVEELVFRARR.PGNTH....-PVPVGLDVV..S..........GDE.R..A..SFLCTVVDGRPIE..VAPGSTADRVG....lRVEYDVHQFARALYGRYSGHAHTAR........
A0A840QJV9_9PSEU/9-116 ..............VEPLLRSAACGEHELASTIERIGLE...QTTDVVVAEMEMRCEP.PRLSS....-SVPFRFEVL..F..........KDA.R..S..TRDLTIGSNGL--..AVAHHHEAPVA.....VVRFDAIDLLESLFGPSGRRPH---vsr.....
A0A318LVD0_9PSEU/11-119 ............vr--ALLTVTEPGH-VADEELLALGTG...RVARTALGELLHRARL.SDLAG....TRVTVEFRWG..C..........GTE.E..V..VLCLVVESGKAE-..IAEHPREAPGA.....IVTQRLAEVVLALYGPADPVPAATR........
A0A5Q0GY58_SACSY/7-117 ..............VRRLVSAAGAGPDEVAAAIGDVGAE...RAADVLVDEVVFRATW.PLLGA...aDRVVVRVALR..H..........GGT.T..T..ARLVTATADGVA-..FGPDDGTAPDA.....TVVQDLAEVVRLVFGPAGGPGAHTR........
A0A7K0D1A1_9NOCA/10-117 ............ad--RLFTAAGSDGDTLTECIANIGSE...RVARTVLAELLDRAPL.RGRPP....--ADILFRMH..M..........PST.T..V..ELGILVDDVAKT-..AVTAPPAEPTA.....TIEQSLPEMVRMVFGPRSAAPCATR........
A0A562I249_MICOL/4-107 ...........ttl---LLAAAETRDGDVAGAIERVGAE...AAARAVFDEVLFRARL.DEIAA...pDGAATVLTLV..H..........DGA.E..H..R--FPVPNPSAY-..-----PDLPPV.....VITQGLAECVRALYGPRESVTDGTR........
#=GC seq_cons ...............ccLltAAsusss-lssslcclGsc...plAplLlcElhhRsch.ss.ss.....slsltlcls..a..........suc.p..h..shslplssutsh...stsupssssss.....plph-Ls-LlRtLaGPssttts...........
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