#=GF ID   NPHI_C
#=GF AC   PF08469.14
#=GF DE   Nucleoside triphosphatase I C-terminal
#=GF AU   Wuster A;0000-0003-4162-5931
#=GF SE   Pfam-B_4183 (release 18.0)
#=GF GA   22.30 22.30;
#=GF TC   22.60 24.00;
#=GF NC   21.50 21.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   1850911
#=GF RT   DNA sequence of the nucleoside triphosphate phosphohydrolase I
#=GF RT   (NPH I) of the Choristoneura biennis entomopoxvirus. 
#=GF RA   Yuen L, Noiseux M, Gomes M; 
#=GF RL   Virology 1991;182:403-406.
#=GF DR   INTERPRO; IPR013676;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This viral domain is found to the C-terminus of Poxvirus
#=GF CC   nucleoside triphosphatase phosphohydrolase I (NPH I, [1])
#=GF CC   together with the helicase conserved C-terminal domain
#=GF CC   (Pfam:PF00271).
#=GF SQ   47
#=GS Q8V3L0_SWPV1/483-630      AC Q8V3L0.1
#=GS D3IZL9_9POXV/485-631      AC D3IZL9.1
#=GS NTP1_VACCC/483-630        AC P20637.1
#=GS A0A385H9J1_FOWPV/485-633  AC A0A385H9J1.1
#=GS Q6VZS3_CNPV/482-630       AC Q6VZS3.1
#=GS A0A1L3IZK5_9POXV/221-368  AC A0A1L3IZK5.1
#=GS A0A7R5WD16_9POXV/506-661  AC A0A7R5WD16.1
#=GS A0A7H0DN95_MONPV/483-630  AC A0A7H0DN95.1
#=GS Q0NP93_9POXV/483-630      AC Q0NP93.1
#=GS G3EIH5_9POXV/483-630      AC G3EIH5.1
#=GS A0A0H4Y1H3_9POXV/483-628  AC A0A0H4Y1H3.1
#=GS Q6TVP8_ORFSA/485-631      AC Q6TVP8.1
#=GS A0A1B3B664_LSDV/484-631   AC A0A1B3B664.1
#=GS Q775S8_CAMPS/483-630      AC Q775S8.1
#=GS Q0GNW8_HSPV/483-630       AC Q0GNW8.1
#=GS Q9JF98_VACCT/421-568      AC Q9JF98.1
#=GS A0A1B1MRM1_9POXV/483-629  AC A0A1B1MRM1.1
#=GS NTP1_MSEPV/492-641        AC Q9YW39.1
#=GS A0A2U9QHP8_9POXV/483-629  AC A0A2U9QHP8.1
#=GS NTP1_RFVKA/483-630        AC Q9Q8Z2.1
#=GS NTP1_MCV1/482-629         AC Q98267.1
#=GS E2CZY1_9POXV/483-630      AC E2CZY1.1
#=GS Q08F85_DPV84/485-632      AC Q08F85.1
#=GS NTP1_MYXVL/483-630        AC Q9Q8L4.1
#=GS NTP1_AMEPV/493-642        AC P29814.2
#=GS W6JPK4_9POXV/491-640      AC W6JPK4.1
#=GS A0A3F2YKP4_SHEVT/484-631  AC A0A3F2YKP4.1
#=GS Q9DHM5_YLDV/483-630       AC Q9DHM5.1
#=GS A0A097IVW4_9POXV/485-632  AC A0A097IVW4.1
#=GS NTP1_VAR67/483-630        AC P0DOQ3.1
#=GS A0A6B9R5R2_9POXV/465-612  AC A0A6B9R5R2.1
#=GS F1AX80_ORFV/485-631       AC F1AX80.1
#=GS A0A0M3ZCM6_9POXV/438-586  AC A0A0M3ZCM6.1
#=GS Q08FQ5_DPV83/485-632      AC Q08FQ5.1
#=GS Q070D3_CPRVZ/479-624      AC Q070D3.1
#=GS NTP1_YMTV5/483-630        AC Q9QB93.1
#=GS H6TA77_9POXV/485-632      AC H6TA77.1
#=GS A0A223FNF1_9POXV/483-630  AC A0A223FNF1.1
#=GS E3T4Q1_CROVB/497-566      AC E3T4Q1.1
#=GS A0A220T6E9_9POXV/484-631  AC A0A220T6E9.1
#=GS F1AX81_ORFV/1-145         AC F1AX81.1
#=GS NTP1_VACCW/483-630        AC P05807.1
#=GS A0A2C9DT64_9POXV/482-629  AC A0A2C9DT64.1
#=GS A0A1V0QGS6_CNPV/482-630   AC A0A1V0QGS6.1
#=GS NTP1_FOWPN/485-633        AC O72907.1
#=GS U3UBK7_9POXV/483-630      AC U3UBK7.1
#=GS A0A223FMW0_9POXV/483-630  AC A0A223FMW0.1
Q8V3L0_SWPV1/483-630                 HMCTPEERKYVNVHFIIARMSNGE.......PTVDEDLLEIIRTKSKEFTQLFKILRESSIEWIYDTQKNFS.PV.DDESGWLALISRSIDMNLKS.KEVEKIVSGQNIWYSTSNRLVMINK.GFKTED.GRIFDTEGNYIQDL....PTNPIIK..IHNDKLVYI..............
D3IZL9_9POXV/485-631                 HEMTPPDRRYVNVHFVVARQDSGA.......ATVDEDLLDLIRDKSRQFTQLFRVLKRCSLEWVREAFTDFA.PL.EDDSGWSALVARPADARGAA.-RAARLADGQSVWYSTSTALVTVRK.GFLERG.GRLFDDDGNFLTVL....GETPTVR..VSGGRLVYV..............
NTP1_VACCC/483-630                   HVLTPPERRYVNVHFIMARLSNGM.......PTVDEDLFEIIQSKSKEFVQLFRVFKHTSLEWIHANEKDFS.PI.DNESGWKTLVSRAIDLSSKK.NITNKLIEGTNIWYSNSNRLMSINR.GFKGVD.GRVYDVDGNYLHDM....PDNPVIK..IHDGKLIYI..............
A0A385H9J1_FOWPV/485-633             HVNNPPERRYVNVYFVVAKLSSGR.......SSVDDILLDIIQSKSKEFSQLYKVFKHSSIEWIYSNYTDFQ.TV.DDEKGFKKLISRNIILDENTiTNKKKLTMGENIWYSFSSSLVSIHR.GFKSMD.NKIYDSEGFFITVL....PDKPTIK..IYEGKLIYI..............
Q6VZS3_CNPV/482-630                  HMNNSPERRYVNVYFVVAKLASGG.......TSVDEVLLDIIRAKSKEFSQLYRVLKYSSIEWIYSQYVDFR.PV.DDESGFRKLISRPLVLDENMaVGKTKLITGENIWYSFSVSLVSIYK.GFKSLD.NKIYDSEGFFLTEL....PENPIIK..IHNDKLVYI..............
A0A1L3IZK5_9POXV/221-368             HVNTPKNMRYVNVHFIIARLNNGD.......ITVDDDLLDIIKSKSKEFLQLFNIFKETSIEWIYKNQVSFP.EV.HDDSGWIPLISRPIDITQKI.KEVSKIVLGENIWYSNSRNLISINK.GFKTDD.GRIFDIDGNYITTI....PSNPNIK..IHNNKLVYV..............
A0A7R5WD16_9POXV/506-661             HEELPEEQRYVNVHILLSHTNDDDmartiktKSVDQEILDIVIRKEIQKQEIIRLFDQTCIETIHKEFPAEI.-G.REPTDFEILTNN-AYVPQTL.--VTLQKKLVMISYTFSPDFNIVYKnGYMDKEtGTVYDETRKEIGVIv.meNSQYVIK..IVDNQLVYL..............
A0A7H0DN95_MONPV/483-630             HVLTPPERRYVNVHFIMARLSNGM.......PTVDEDLFEIIQNKSKEFVQLFRVFKHTSLEWIHANEKDFS.PI.DNESGWKTLVSRAIDLSSKK.NITNKLIEGTNIWYSNSNRLISINR.GFKGVD.GRVYDVDGNYLHDM....PDNPVIK..IHDGKLIYI..............
Q0NP93_9POXV/483-630                 HVLTPPERRYVNVHFIMARLSNGM.......PTVDEDLFEIIQSKSKEFVQLFRVFKHTSLEWIHANEKDFS.PI.DNESGWKTLVSRAIDLSSKK.NITNKLIEGTNIWYSNSNRLMSINR.GFKGVD.GRVYDVDGNYLHDM....PDNPVIK..IHDGKLIYI..............
G3EIH5_9POXV/483-630                 HALTPSDRRYVNVHFILARLYNGS.......PTVDEDLFEIIKDKSKEFVQLFRVLKRTSIEWIHENEKDFS.PI.DNESGWKTLISRTIDLSSKT.NINNKLIEGSNIWYSNSTRMLTINR.GFKGID.GRIYDSDGYYIYDM....PENPVIK..IYDGKLVFI..............
A0A0H4Y1H3_9POXV/483-628             HQMLDSSRWYTNVNFIICKKSKGT.......-SVDQELLEVVKGKSRQIKQLFEVFRQCSIETLFERVNEEN.ALpDNEDKLKAYLCEPIEFKTKT.-YKMGFVNVKTVYYSFDLILKNIHV.GYIGDN.-IIYSEDGHIIGDV....TKDTIIR..IKNKKLIYV..............
Q6TVP8_ORFSA/485-631                 HEMTPPDRRYVNVHFVVARQDSGA.......ATVDEDLLALIRDKSRQFTQLFRVLKRCSLEWVREAFTDFA.PL.EDDSGWSALVARPADARGPA.-RAARLADGQSVWYSTSTALVTVRK.GFLERG.GRLFDDDGNFLTAL....GDPPTVR..VSGGRLVYV..............
A0A1B3B664_LSDV/484-631              HVNTPKDRRYVNVHFIIARLSNGE.......STVDDDLLEIIRTKSKEFSQLFKVLKESSIEWIYDHQKNFS.PV.DDESGWIPLISRSIDMNAKT.KEIVKVVEGENIWFSTSKRLVNIHK.GFKTND.GKIFDAEGNFLQTM....PENPIIK..IQNNKLIYI..............
Q775S8_CAMPS/483-630                 HVLTPPERRYVNVHFIMARLSNGM.......PTVDEDLFEIIQSKSKEFVQLFRVFKHTSLEWIHANEKDFS.PI.DNESGWKTLVSRAIDLSSKK.NITNKLIEGTNIWYSNSNRLMSINR.GFKGVD.GRVYDVDGNYLHDM....PDNPVIK..IHDGKLIYI..............
Q0GNW8_HSPV/483-630                  HVLTPPERRYVNVHFIMARLSNGM.......PTVDEDLFEIIQSKSKEFVQLFRVFKHTSLEWIHANEKDFS.PI.DNESGWKTLVSRAIDLSSKK.NITNKLIEGTNIWYSNSNRLMSINR.GFKGVD.GRVYDVDGNYLHDM....PDNPVIK..IHDGKLIYI..............
Q9JF98_VACCT/421-568                 HVLTPPERRYVNVHFIMARLSNGM.......PTVDEDLFEIIQSKSKEFVQLFRVFKHTSLEWIHANEKDFS.PI.DNESGWKTLVSRAIDLSSNK.NITNKLIEGTNIWYSNSNRLMSINR.GFKGVD.GRVYDVDGNYLHDM....PDNPVIK..IHDGKLIYI..............
A0A1B1MRM1_9POXV/483-629             HALNAPDRRYVNVYFVIARLSSGA.......PTVDEDLLEVIQNKTREFSQLFSVYKQTSIEWIYEHYTAFS.PI.NDESAWQSLISRPMLVTTTE.-NVNKTVNGENIWYARSTAMITIYN.GFKTSD.GKVYDKDGIFLLNM....PADPIIK..INNNKLVYI..............
NTP1_MSEPV/492-641                   HEELPIEKRYVNVHFIIASTIDGK.......-SVDKEIFDLIKSKQDKINVLNSFMKVISIEQIHSKYKYAE.PV.ENEYIFNNI--RHTKIDDVNeNNVITKIIVSPIYYCSEDNLNIIYN.GYLDKK.TGIIYSNNIPIAKLi..lDENNIYKffIKDDKLVYI..............
A0A2U9QHP8_9POXV/483-629             HVLNPPDRRYVNVYFVIARTESGI.......PTVDEDLLEIIQNKAREFTQLLRILKHASIEWIYNKYTAFA.PV.DNESAWISLISRPINISAKD.-KIDKLIQGENIWYARSVTLVTLYK.GFKTVD.GKVYDKDGNYLLNM....PINPVIR..IHNGKLVYI..............
NTP1_RFVKA/483-630                   HVLTPEHRRYVYVHFIIARLSNGD.......PTVDEDLLDIIRNKSKEFTQLFKVFKHTSIEWIYEHQTNFS.PV.DDESGWGALISRSIDENPTT.KRVPRIARGQNIWYSHSNRMITVYK.GFKTDD.GRLFDSDGNFIQTI....QANPVIK..IHNNKLVYV..............
NTP1_MCV1/482-629                    HANNPPERRYVNVHFVVAQLGSGA.......PSVDDDLLEIIQNKAREFSQLYRVLKLASIEWIHQHCREFA.PV.DDEAGFRALCSRAIDVTRGA.STRRALATGENIWYAFSTLMITVHP.GFKTED.GRVYDADGNFLTTM....PERPIVR..VQGTRLVYI..............
E2CZY1_9POXV/483-630                 HVLTPEHRRYVNVHFIVARLSNGD.......ATVDEDLLDIIRTKSKEFTQLFKVFKHTSIEWIYEHQTDFS.PV.DNESGWSALISRSIDENPTT.KRVPHVVKGQNIWYSHSNRLIAVYK.GFKTDD.GRLFDSDGNFIQTI....QDNPVIK..IHNDKLVYV..............
Q08F85_DPV84/485-632                 HIFTPEERRYVNVHFIIARLSNGD.......STVDEDLLDIIRTKSKEFTQLFKVLKESSIEWIYEHHKNFS.PI.DDESGWTSLISRAIDMNSKP.REIIHVAEGQNIWYSHSNRLITIYR.GFKTED.GKIYDTDGNFIQNM....PDNPIIK..IHNDKLVYL..............
NTP1_MYXVL/483-630                   HVLTPEHRRYVNVHFIVARLSNGD.......ATVDEDLLDIIRTKSKEFTQLFKVFKHTSIEWIYEHQTDFS.PV.DNESGWSALISRSIDENPTT.KRVPHVVKGQNIWYSHSNRLIAVYK.GFKTDD.GRLFDSDGNFIQTI....QDNPVIK..IHNDKLVYV..............
NTP1_AMEPV/493-642                   HKDLPQEYRYVNVHFLIS-YTNNR.......KSVDKEILDIIKDKQGKINVIFDLLKSSSIESIHNTYKYIE.PA.ENEIIFDTI--RKTRMKEMNvSNVIINIKLYPISYCKDYDRATILK.GLLNKD.TNIVYKDNTAVAKLmidkDNIPIFI..IENDTLIYI..............
W6JPK4_9POXV/491-640                 HMELEMENRYVTVHFIIS-YTIND.......KSVDEEILNLIKQKKNNISVLFNLLKSVSIEHIHNTYKNIE.PI.ENEYIFDTL--RRTKMKELNiTNVVANILVTPIFYCNEDNISVIFE.GYLDKK.NNIVYSNNIPIATIkldnSNRPIFI..IVEDKLVYI..............
A0A3F2YKP4_SHEVT/484-631             HVNTPKNRRYVNVHFIIARLSNGE.......STVDDDLLEIIRTKSKEFSQLFKVLKESSIEWIYDHQKNFS.PV.DDESGWIPLISRSIDMNAKT.KEIVKVVEGENIWFSTSKRLVNIHK.GFKTND.GKIFDTEGNFLQTM....PKNPIIK..IQSNKLIYI..............
Q9DHM5_YLDV/483-630                  HANTPPNRRYVNVYFIIARLSNGE.......PTVDEDLINIIKTKSKEFLQLFKVFKESSIEWIYENKKNFY.PV.NDESGWRALTSRIVDVNVKS.KKIVQVVQGQNIWFSNSSRMITIHK.GFKTLD.GKIFDVDGNFIQNM....PVNPVIK..IHNNKLVYI..............
A0A097IVW4_9POXV/485-632             HINTPKNMRYVNVHFIISRLNNGD.......FTVDDDLLDIIKTKSKEFSQLFKVLKETSIEWIYNNQVSFP.EV.NDDSGWIPLISRAIDINQKI.KEVSKIVLGENIWYSNSINLISINK.GFKTDD.GRIFDIDGNYITTM....PKYPNIK..IYNNKLVYV..............
NTP1_VAR67/483-630                   HVLTPPERRYVNVHFIMARLSNGM.......PTVDEDLFEIIQSKSKEFVQLFRVFKHTSLEWIHANEKDFS.PI.DNESGWKTLVSRAIDLSSKK.NITNKLIEGTNIWYSNSNRLMSINR.GFKGVD.GRVYDVDGNYLHDM....PDNPVIK..IHDGKLIYI..............
A0A6B9R5R2_9POXV/465-612             HLMTPPERRYVNVYFVIARMANGD.......PTVDEELLDIIYNKSKEFSQLFHVFKRASIEYINSTKTNFH.PI.DNDDGWKTLTSRSIDTSSNN.ESVTRLIEGENIWYSTSSRIVTIRK.GFKGKD.GKIYDIDGNYMFNM....PEIPTIK..IYNKKLVYI..............
F1AX80_ORFV/485-631                  HEMTPPDRRYVNVHFVVARQDSGA.......ATVDEDLLALIRDKSRQFTQLFRVLKRCSLEWVREAFTDFA.PL.EDDSGWSALVARPADARGPA.-RAARLADGQSVWYSTSTALVTVRK.GFLERG.GRLFDEDGNFLTAL....GDPPTVR..VSGGRLVYV..............
A0A0M3ZCM6_9POXV/438-586             HVNNPPDRRYVNVYFVIAKLASGG.......STVDDLLLDIIQSKSKEFSQLYKVLKRSSIEWIYSNYTDFQ.LV.DDEKGFRKLISRQITIDENTiINKKKLILGENIWYSFSTSMVSVYR.GFKSKD.NKIYDSDGFFITTL....PENPIIK..IHDGKLIYI..............
Q08FQ5_DPV83/485-632                 HIFTPEDRRYVNVHFIIARLSNGD.......STVDEDLLDIIRTKSKEFTQLFKVLKESSIEWIYEHHKNFS.PI.DDESGWTSLISRAIDMNSKP.REIIHVAEGQNIWYTHSNRLITIYR.GFKTED.GKIYDTDGNFIQNM....PDNPIIK..IHNDKLVYL..............
Q070D3_CPRVZ/479-624                 HVNNVSDRRYLNVHFIVATLADGL.......-SVDQELLDIIQQKSREFNQLYSVLKRASIEYIYANYPPPAvAL.ENEKNFQKLISRPVEFSARR.-TQAVVVSGESVWYSFSSLMTSIHK.GFKHEN.-RIYDTDGNYVATL....EEDPTVR..VSGCKLVYI..............
NTP1_YMTV5/483-630                   HANTPPNRRYVNVYFIIARLSSGE.......PTVDEDLINIIKTKSKEFFQLFKVFKESSIEWIYKNKKDFY.PI.NDESGWRALTSRVVDVNVKS.KRTVQLAQGQNIWFSNSSRMVTIHK.GFKTSD.GKIFDVDGNFIQNM....PINPIIK..IHNDKLVYI..............
H6TA77_9POXV/485-632                 HINTPKNMRYVNVHFIISRLNNGD.......FTVDDDLLDIIKTKSKEFSQLFKVLKETSIEWIYNNQVSFP.EV.NDDSGWIPLISRAIDINQKI.KEVSKIVLGENIWYSNSINLISINK.GFKTDD.GRIFDIDGNYITTM....PKYPNIK..IYNNKLVYV..............
A0A223FNF1_9POXV/483-630             HVLTPPERRYVNVHFILARLSNGG.......TTVDEDLFEIIQNKSREFVQLFRVLKHTSIEWIHLNEKDFS.PV.DNESGWKTLVSRTIDLSSKR.NISNKLIEGSNIWYSNSTRMLTINR.GFKGVD.GRIYDAEGHYIHDM....PENPIIK..IHDGKLVFI..............
E3T4Q1_CROVB/497-566                 HADLPKRKRKVDIYLYLAKTPDNR.......ESVDEYIWKLAKQKAKLINQFEKTMKEHAIDC---------.--.--------------------.-------------------------.------.--------------....-------..---------eifynanydsenpl
A0A220T6E9_9POXV/484-631             HVFTPPQRRYVNVHFIISRLSDGQ.......PTVDEDLLDIIQTKSKEFFQLFRVFKKTSIEWIYANEKDFA.PI.DDESGWKSLITRTIDMDVKN.KEIVQLLEGQNIWYSYSTRLVTILK.GFKSLD.GRIFDSDGNFIQDM....PKNPIIK..IHNKKLVYI..............
F1AX81_ORFV/1-145                    --MTPPDRRYVNVHFVVARQDSGA.......ATVDEDLLALIRDKSRQFTQLFRVLKRCSLEWVREAFTDFA.PL.EDDSGWSALVARPADARGPA.-RAARLADGQSVWYSTSTALVTVRK.GFLERG.GRLFDEDGNFLTAL....GDPPTVR..VSGGRLVYV..............
NTP1_VACCW/483-630                   HVLTPPERRYVNVHFIMARLSNGM.......PTVDEDLFEIIQSKSKEFVQLFRVFKHTSLEWIHANEKDFS.PI.DNESGWKTLVSRAIDLSSNK.NITNKLIEGTNIWYSNSNRLMSINR.GFKGVD.GRVYDVDGNYLHDM....PDNPVIK..IHDGKLIYI..............
A0A2C9DT64_9POXV/482-629             HASNPPERRYVNVHLIIARLNSGA.......SSVDDALLEIIQTKSREFTQLYRVLKLASIEWIYRNFTEFP.HV.EDEAGFKKLVSRAIDLSHDV.TTNRRTAYGENIWYTFSPLIISIHQ.GFKTED.GRVYDTDGHYVTTV....PEPPVVR..VHEGKLVYV..............
A0A1V0QGS6_CNPV/482-630              HMNNPPERRYVNVYFVVAKLASGG.......SSVDEVLLDIIRSKSKEFTQLYRVLKYSSIEWIYSQYLDFK.PI.EDESGFRKLISRPLVLDENItVNKTKLITGENIWYSFSISLVSIYK.GFKSSD.NKIYDSEGFFIADL....PEHPVIK..IYNDKLIYI..............
NTP1_FOWPN/485-633                   HVNNPPERRYVNVYFVVAKLSSGR.......SSVDDILLDIIQSKSKEFSQLYKVFKHSSIEWIYSNYTDFQ.TV.DDEKGFKKLISRNIILDENTiTNKKKLTMGENIWYSFSSSLVSIHR.GFKSMD.NKIYDSEGFFITVL....PDKPTIK..IYEGKLIYI..............
U3UBK7_9POXV/483-630                 HALTPPERRFVRVHFVVARLPSGA.......PSVDDDMLDIIQTKAREFSQIFRVLKHASIEWIHAHHKDFS.PV.DDESGWRAIVTRPIDVSARQ.EHVQQLVEGENIWYSLSTVIVTVHR.GFKSND.GRVFDADGNFLTNM....PETPVVR..IHGDRLVYV..............
A0A223FMW0_9POXV/483-630             HVLTPPERRYVNVHFILARLSNGV.......PTVDEDLFEIIQNKSREFVQLFRVLKHTSIEWIHLNEKDFS.PV.DNESGWKTLVSRTIDLSSKR.NISNKLIEGSNIWYSNSTRMLSINR.GFKGVD.GRIYDAEGHYIHDM....PENPIIK..IHDGKLVFI..............
#=GC seq_cons                        Hs.TPs-RRYVNVHFIlARLusGt.......sTVDEDLL-IIpsKSKEFsQLF+VhKcoSIEWIaps.psFu.Pl.DsESGWpsLlSRsIDhsspp.ppss+llpGpNIWYSpSspLloIp+.GFKspD.G+laDsDGNalpsh....P-sPlIK..IassKLVYI..............
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