#=GF ID NUMOD3
#=GF AC PF07460.15
#=GF DE NUMOD3 motif
#=GF AU Pietrokovski S;0000-0001-8573-5863
#=GF SE Pietrokovski S
#=GF GA 20.40 11.10;
#=GF TC 20.40 11.10;
#=GF NC 20.30 11.00;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP Motif
#=GF RN [1]
#=GF RM 13678957
#=GF RT New types of conserved sequence domains in DNA-binding regions
#=GF RT of homing endonucleases.
#=GF RA Sitbon E, Pietrokovski S;
#=GF RL Trends Biochem Sci 2003;28:473-477.
#=GF DR INTERPRO; IPR003611;
#=GF DR SCOP; 1i3j; fa;
#=GF DR SO; 0001067; polypeptide_motif;
#=GF CC NUMOD3 is a DNA-binding motif found in homing endonucleases and
#=GF CC related proteins. It occurs on its own or in tandem repeats in
#=GF CC GIY-YIG (Pfam:PF01541) and HTH proteins. It constitutes a
#=GF CC beta-turn-loop-helix subregion of the the DNA-binding domain of
#=GF CC I-TevI homing endonuclease (Swiss:P13299) [1].
#=GF SQ 1589
#=GS A0A7J7IHK1_9RHOD/128-164 AC A0A7J7IHK1.1
#=GS A7IWV8_PBCVN/170-200 AC A7IWV8.1
#=GS A0A411BAN9_9CAUD/99-126 AC A0A411BAN9.1
#=GS A0A2S6VR85_9GAMM/125-151 AC A0A2S6VR85.1
#=GS A0A4Q3E624_9RICK/85-114 AC A0A4Q3E624.1
#=GS A0A142EZU2_9CAUD/111-134 AC A0A142EZU2.1
#=GS A0A251PUN2_PRUPE/126-155 AC A0A251PUN2.1
#=GS A0A6J0PRS7_ELAGV/147-176 AC A0A6J0PRS7.1
#=GS A0A1H4W968_9ACTN/192-208 AC A0A1H4W968.1
#=GS A0A2G5CHX0_AQUCA/116-148 AC A0A2G5CHX0.1
#=GS A0A813DT68_POLGL/64-83 AC A0A813DT68.1
#=GS A0A6P5X7V8_DURZI/1-28 AC A0A6P5X7V8.1
#=GS V4JX69_EUTSA/113-142 AC V4JX69.1
#=GS A0A0V7ZSG6_9CYAN/97-117 AC A0A0V7ZSG6.1
#=GS A0A830HL13_9CHLO/140-171 AC A0A830HL13.1
#=GS A0A7G4AWJ4_9VIRU/34-56 AC A0A7G4AWJ4.1
#=GS A0A804IJL8_MUSAM/127-156 AC A0A804IJL8.1
#=GS I7J406_BPPR1/178-201 AC I7J406.1
#=GS A0A7M1RR13_9CAUD/119-139 AC A0A7M1RR13.1
#=GS A7J7R3_PBCVF/110-144 AC A7J7R3.1
#=GS A0A452YA83_AEGTS/186-214 AC A0A452YA83.1
#=GS A0A1S3ZUV0_TOBAC/119-148 AC A0A1S3ZUV0.1
#=GS A0A1S5R3N2_9CAUD/92-128 AC A0A1S5R3N2.1
#=GS K0RCK9_THAOC/246-282 AC K0RCK9.1
#=GS R3WJG0_9ENTE/78-102 AC R3WJG0.1
#=GS A0A4Q3E4E3_9RICK/147-172 AC A0A4Q3E4E3.1
#=GS A0A5M6CBU9_9BACT/71-93 AC A0A5M6CBU9.1
#=GS A0A0B4ZZJ6_9CAUD/123-142 AC A0A0B4ZZJ6.1
#=GS A0A444YLN5_ARAHY/156-185 AC A0A444YLN5.1
#=GS A0A443PMY8_9MAGN/168-199 AC A0A443PMY8.1
#=GS A0A7N0T2J9_KALFE/117-146 AC A0A7N0T2J9.1
#=GS M4QPC0_9CAUD/130-148 AC M4QPC0.1
#=GS A0A7G9VY59_9CAUD/161-179 AC A0A7G9VY59.1
#=GS A0A6J5X5B9_PRUAR/119-150 AC A0A6J5X5B9.1
#=GS A0A1U8PEE9_GOSHI/1-28 AC A0A1U8PEE9.1
#=GS A0A5A7UFU5_CUCME/122-151 AC A0A5A7UFU5.1
#=GS A0A0A2VMZ4_BEABA/243-277 AC A0A0A2VMZ4.1
#=GS A0A3Q9R9B1_9CAUD/63-77 AC A0A3Q9R9B1.1
#=GS A0A565BFA8_9BRAS/110-138 AC A0A565BFA8.1
#=GS A8I870_CHLRE/132-152 AC A8I870.1
#=GS A0A835XI02_9CHLO/245-262 AC A0A835XI02.1
#=GS A0A5B9ND36_9CAUD/169-191 AC A0A5B9ND36.1
#=GS R0GQI0_9BRAS/103-136 AC R0GQI0.1
#=GS A0A6A2WJL5_HIBSY/126-155 AC A0A6A2WJL5.1
#=GS A7J7R3_PBCVF/216-242 AC A7J7R3.1
#=GS A0A4R5DV65_9BACT/85-113 AC A0A4R5DV65.1
#=GS A0A0E0LYW5_ORYPU/408-439 AC A0A0E0LYW5.1
#=GS A0A6J0KMU2_RAPSA/123-158 AC A0A6J0KMU2.1
#=GS A0A5B0HCQ9_9BURK/118-140 AC A0A5B0HCQ9.1
#=GS F8A5X8_CELGA/175-215 AC F8A5X8.1
#=GS A0A2K3DUG2_CHLRE/100-119 AC A0A2K3DUG2.1
#=GS I0Z3I3_COCSC/51-85 AC I0Z3I3.1
#=GS A8ZRI9_DEIGD/114-143 AC A8ZRI9.1
#=GS A0A2K3E0S7_CHLRE/27-54 AC A0A2K3E0S7.1
#=GS A0A0F6YPE9_9CAUD/158-204 AC A0A0F6YPE9.1
#=GS A0A366HCJ3_9BURK/146-172 AC A0A366HCJ3.1
#=GS V4UR58_CITCL/122-155 AC V4UR58.1
#=GS A0A314V0P6_PRUYE/126-150 AC A0A314V0P6.1
#=GS A0A8J4RPQ4_9ROSI/117-148 AC A0A8J4RPQ4.1
#=GS A0A0E0M695_ORYPU/101-129 AC A0A0E0M695.1
#=GS A0A248H477_9CAUD/116-139 AC A0A248H477.1
#=GS C1FDC6_MICCC/241-272 AC C1FDC6.1
#=GS A0A5Q2W882_9CAUD/136-158 AC A0A5Q2W882.1
#=GS A0A2L0UZL8_9CAUD/159-181 AC A0A2L0UZL8.1
#=GS A0A8R7P1T4_TRIUA/92-121 AC A0A8R7P1T4.1
#=GS A0A1S4DYR7_CUCME/127-157 AC A0A1S4DYR7.1
#=GS A0A830BUW0_9LAMI/140-169 AC A0A830BUW0.1
#=GS A0A0K9Q9P7_SPIOL/117-146 AC A0A0K9Q9P7.1
#=GS A0A879R2G8_9CAUD/151-185 AC A0A879R2G8.1
#=GS A0A8H7QNT0_9FUNG/125-157 AC A0A8H7QNT0.1
#=GS C4MYI3_9CAUD/164-191 AC C4MYI3.1
#=GS H9CNU2_TALMQ/245-281 AC H9CNU2.1
#=GS A0A3N2MAI7_9BACT/157-189 AC A0A3N2MAI7.1
#=GS A0A6M5CEU2_9CAUD/130-159 AC A0A6M5CEU2.1
#=GS A0A6P6SGU0_COFAR/131-161 AC A0A6P6SGU0.1
#=GS A0A255SU34_9BACT/200-223 AC A0A255SU34.1
#=GS J7KEM1_9CAUD/133-156 AC J7KEM1.1
#=GS D9I6H0_9CAUD/196-217 AC D9I6H0.1
#=GS A0A6A4MEL8_9ERIC/134-163 AC A0A6A4MEL8.1
#=GS A0A1X6PKV4_PORUM/29-63 AC A0A1X6PKV4.1
#=GS A0A5J5GHY6_9BACL/129-167 AC A0A5J5GHY6.1
#=GS A7IW81_PBCVN/134-168 AC A7IW81.1
#=GS A0A8X8Y9L4_SALSN/135-164 AC A0A8X8Y9L4.1
#=GS B7G1A0_PHATC/329-345 AC B7G1A0.1
#=GS A0A4S4FW77_9MICO/215-233 AC A0A4S4FW77.1
#=GS A0A433Q156_9FUNG/132-153 AC A0A433Q156.1
#=GS A0A433D829_9FUNG/151-173 AC A0A433D829.1
#=GS A0A2K1II33_PHYPA/140-169 AC A0A2K1II33.1
#=GS A0A0B6VTT1_9CAUD/128-154 AC A0A0B6VTT1.1
#=GS J3MA83_ORYBR/122-152 AC J3MA83.1
#=GS A0A8E7FM92_9CAUD/198-231 AC A0A8E7FM92.1
#=GS A0A813K3Y9_POLGL/67-86 AC A0A813K3Y9.1
#=GS A0A835VY44_9CHLO/117-135 AC A0A835VY44.1
#=GS A0A223LJI1_9CAUD/170-209 AC A0A223LJI1.1
#=GS A0A2M9PFK7_9RHOB/14-41 AC A0A2M9PFK7.1
#=GS A0A2K3DRZ3_CHLRE/125-144 AC A0A2K3DRZ3.1
#=GS A0A514CT87_9CAUD/121-137 AC A0A514CT87.1
#=GS A0A6G6XH43_9CAUD/166-201 AC A0A6G6XH43.1
#=GS A0A1U8KLK1_GOSHI/121-155 AC A0A1U8KLK1.1
#=GS A0A4Q2LHF7_9BACL/111-131 AC A0A4Q2LHF7.1
#=GS A0A0E0IQB4_ORYNI/100-128 AC A0A0E0IQB4.1
#=GS A0A076G735_9CAUD/144-179 AC A0A076G735.1
#=GS A7K8Z7_9PHYC/109-145 AC A7K8Z7.1
#=GS A0A6J1ITB7_CUCMA/123-153 AC A0A6J1ITB7.1
#=GS A0A7G9VY59_9CAUD/122-141 AC A0A7G9VY59.1
#=GS A0A386K7L3_9CAUD/181-202 AC A0A386K7L3.1
#=GS A0A0B5A2B5_9CAUD/106-127 AC A0A0B5A2B5.1
#=GS E5EYT8_BPAC4/151-169 AC E5EYT8.1
#=GS A0A2R6WUI9_MARPO/160-189 AC A0A2R6WUI9.1
#=GS Q84603_PBCV1/138-174 AC Q84603.2
#=GS A0A813GCE7_POLGL/240-260 AC A0A813GCE7.1
#=GS A7IWC1_PBCVN/92-119 AC A7IWC1.1
#=GS A0A6I1FPB1_9BACI/169-190 AC A0A6I1FPB1.1
#=GS I7HDH7_9CAUD/116-138 AC I7HDH7.1
#=GS I0J2P6_9CAUD/140-162 AC I0J2P6.1
#=GS A0A5Q2W882_9CAUD/153-189 AC A0A5Q2W882.1
#=GS A0A1J0F9L5_9PHYC/90-109 AC A0A1J0F9L5.1
#=GS A0A7J0FEY6_9ERIC/91-120 AC A0A7J0FEY6.1
#=GS R9U325_BOTFB/273-309 AC R9U325.1
#=GS A0A0K0PSY4_SCLS1/147-183 AC A0A0K0PSY4.1
#=GS A0A251PUF5_PRUPE/127-156 AC A0A251PUF5.1
#=GS K4IG49_9CAUD/169-209 AC K4IG49.1
#=GS A0A8H7QEU7_9FUNG/622-658 AC A0A8H7QEU7.1
#=GS A0A828RUI7_9FIRM/35-60 AC A0A828RUI7.1
#=GS A0A834XE16_9FABA/197-226 AC A0A834XE16.1
#=GS A7K9Q1_9PHYC/133-169 AC A7K9Q1.1
#=GS A0A4R5DV65_9BACT/135-160 AC A0A4R5DV65.1
#=GS A7RC94_PBCVA/174-204 AC A7RC94.1
#=GS A0A1Y2U8B4_9PEZI/178-215 AC A0A1Y2U8B4.1
#=GS A0A514CT87_9CAUD/192-213 AC A0A514CT87.1
#=GS A7K9F8_9PHYC/207-245 AC A7K9F8.1
#=GS A0A7N0ZYD4_KALFE/113-142 AC A0A7N0ZYD4.1
#=GS A0A2P6VEI2_9CHLO/139-174 AC A0A2P6VEI2.1
#=GS K5YQM6_9PROT/23-44 AC K5YQM6.1
#=GS A0A0C5PI24_9CAUD/141-163 AC A0A0C5PI24.1
#=GS I0J322_9CAUD/169-209 AC I0J322.1
#=GS A0A097J0Z1_BPR03/166-201 AC A0A097J0Z1.1
#=GS A0A1S3ZHW2_TOBAC/44-75 AC A0A1S3ZHW2.1
#=GS I7HDH7_9CAUD/99-120 AC I7HDH7.1
#=GS A0A0A2V7D3_BEABA/162-199 AC A0A0A2V7D3.1
#=GS A7J784_PBCVF/152-178 AC A7J784.1
#=GS A0A1R0GKZ4_9FUNG/15-43 AC A0A1R0GKZ4.1
#=GS A0A6H0X6H5_9CAUD/102-119 AC A0A6H0X6H5.1
#=GS A7J6F7_PBCVF/231-253 AC A7J6F7.1
#=GS A0A1U8ID36_GOSHI/121-155 AC A0A1U8ID36.1
#=GS A0A5N5G6P5_9ROSA/126-155 AC A0A5N5G6P5.1
#=GS E1A2N3_9CAUD/196-211 AC E1A2N3.1
#=GS A0A481W5U9_9CAUD/93-126 AC A0A481W5U9.1
#=GS A0A024FSJ1_9CAUD/168-197 AC A0A024FSJ1.1
#=GS V7AK28_PHAVU/103-133 AC V7AK28.1
#=GS A0A811RUW7_9POAL/128-159 AC A0A811RUW7.1
#=GS I7GYA4_9CAUD/101-120 AC I7GYA4.1
#=GS Q02677_PODAN/233-249 AC Q02677.1
#=GS A0A0D3CS79_BRAOL/101-130 AC A0A0D3CS79.1
#=GS A0A6B9J0Y3_9CAUD/102-125 AC A0A6B9J0Y3.1
#=GS A0A1I6PRQ2_9CAUL/96-115 AC A0A1I6PRQ2.1
#=GS A0A6A9T8N2_9EURY/256-280 AC A0A6A9T8N2.1
#=GS A0A6M3I023_9CAUD/198-233 AC A0A6M3I023.1
#=GS A0A2K3CPD8_CHLRE/37-57 AC A0A2K3CPD8.1
#=GS A0A1B6PA96_SORBI/128-159 AC A0A1B6PA96.1
#=GS A0A328UAH8_9FIRM/162-185 AC A0A328UAH8.1
#=GS A0A8B8NSY8_9MYRT/114-147 AC A0A8B8NSY8.1
#=GS A0A372Q2J5_9GLOM/166-199 AC A0A372Q2J5.1
#=GS A0A0E0B8P5_9ORYZ/100-128 AC A0A0E0B8P5.1
#=GS A0A5J4Z2S3_PORPP/213-249 AC A0A5J4Z2S3.1
#=GS A0A8H7UYD8_9FUNG/162-189 AC A0A8H7UYD8.1
#=GS A0A4R2JC69_9PSEU/136-164 AC A0A4R2JC69.1
#=GS A0A1J0F9S1_9PHYC/120-144 AC A0A1J0F9S1.1
#=GS A0A845R346_9CLOT/118-139 AC A0A845R346.1
#=GS A7ITJ1_PBCVM/137-151 AC A7ITJ1.1
#=GS J7HXP4_9CAUD/107-129 AC J7HXP4.1
#=GS M4QPC0_9CAUD/82-118 AC M4QPC0.1
#=GS A0A8B8ZKC9_PHODC/140-169 AC A0A8B8ZKC9.1
#=GS A0A2K3E0M3_CHLRE/190-210 AC A0A2K3E0M3.1
#=GS A7K9P3_9PHYC/109-145 AC A7K9P3.1
#=GS A0A7M1RTW7_9CAUD/119-139 AC A0A7M1RTW7.1
#=GS A0A6J0PRW9_ELAGV/50-79 AC A0A6J0PRW9.1
#=GS A7K9F8_9PHYC/142-170 AC A7K9F8.1
#=GS A4RRI4_OSTLU/65-94 AC A4RRI4.1
#=GS A0A6H0X621_9CAUD/105-146 AC A0A6H0X621.1
#=GS A7IV63_PBCVM/131-160 AC A7IV63.1
#=GS A0A6B9SWZ2_9CAUD/88-120 AC A0A6B9SWZ2.1
#=GS A0A2R6QCM3_ACTCC/117-146 AC A0A2R6QCM3.1
#=GS A0A7N0TYK1_KALFE/116-145 AC A0A7N0TYK1.1
#=GS A0A868BQX3_BPFBB/132-149 AC A0A868BQX3.1
#=GS B8C3T4_THAPS/193-211 AC B8C3T4.1
#=GS A0A2H4YGC2_9CAUD/143-168 AC A0A2H4YGC2.1
#=GS A0A7S5QZ88_9CAUD/114-143 AC A0A7S5QZ88.1
#=GS A7IUJ5_PBCVM/185-204 AC A7IUJ5.1
#=GS A0A433AFW0_9FUNG/75-105 AC A0A433AFW0.1
#=GS A0A7T6ZLU2_9CAUD/99-123 AC A0A7T6ZLU2.1
#=GS A0A858MU60_9CAUD/139-160 AC A0A858MU60.1
#=GS A0A151SWT5_CAJCA/1-28 AC A0A151SWT5.1
#=GS A0A6I9SRZ0_SESIN/133-162 AC A0A6I9SRZ0.1
#=GS A0A836BBD7_9CHLO/58-84 AC A0A836BBD7.1
#=GS W1PBI6_AMBTC/59-88 AC W1PBI6.1
#=GS A0A6B9J4W1_9CAUD/172-191 AC A0A6B9J4W1.1
#=GS A7K9F8_9PHYC/173-203 AC A7K9F8.1
#=GS A0A2I4HTW5_JUGRE/130-160 AC A0A2I4HTW5.2
#=GS A0A1B6PP39_SORBI/84-113 AC A0A1B6PP39.1
#=GS A0A8H7QNT0_9FUNG/198-222 AC A0A8H7QNT0.1
#=GS A0A1Y4HEK6_9BACT/6-42 AC A0A1Y4HEK6.1
#=GS A0A7J7CHD6_TRIWF/112-140 AC A0A7J7CHD6.1
#=GS A0A1J0F9L5_9PHYC/124-160 AC A0A1J0F9L5.1
#=GS A0A218KBZ6_9CAUD/160-186 AC A0A218KBZ6.1
#=GS A0A0A2V7D3_BEABA/200-221 AC A0A0A2V7D3.1
#=GS A0A0B6VSL3_9CAUD/120-156 AC A0A0B6VSL3.1
#=GS A0A836BUE9_9CHLO/86-107 AC A0A836BUE9.1
#=GS A0A0D3CQS2_BRAOL/113-141 AC A0A0D3CQS2.1
#=GS R9U337_BOTFB/192-228 AC R9U337.1
#=GS A0A5P1EVT6_ASPOF/142-173 AC A0A5P1EVT6.1
#=GS A0A453A2C8_AEGTS/123-154 AC A0A453A2C8.1
#=GS A7IUJ0_PBCVM/120-144 AC A7IUJ0.1
#=GS A0A813GKC8_POLGL/247-268 AC A0A813GKC8.1
#=GS A0A1H3TM55_9MICO/162-180 AC A0A1H3TM55.1
#=GS Q0ILH1_BPT6/133-158 AC Q0ILH1.1
#=GS A0A6A6KPC4_HEVBR/129-155 AC A0A6A6KPC4.1
#=GS A0A650EX86_9CAUD/88-124 AC A0A650EX86.1
#=GS A0A7D3QMW2_9CAUD/115-135 AC A0A7D3QMW2.1
#=GS A0A0B6VTT4_9CAUD/93-132 AC A0A0B6VTT4.1
#=GS A0A433Q147_9FUNG/57-91 AC A0A433Q147.1
#=GS A7K9P7_9PHYC/91-109 AC A7K9P7.1
#=GS A0A813DT68_POLGL/175-194 AC A0A813DT68.1
#=GS A0A6A2ZY92_HIBSY/134-163 AC A0A6A2ZY92.1
#=GS A0A420JA17_9PEZI/54-68 AC A0A420JA17.1
#=GS A0A4V1M2U9_TREME/158-178 AC A0A4V1M2U9.1
#=GS A0A8H9GH41_9MICO/170-206 AC A0A8H9GH41.1
#=GS A7IW81_PBCVN/92-111 AC A7IW81.1
#=GS A0A0D9XIE7_9ORYZ/109-137 AC A0A0D9XIE7.1
#=GS A0A858MTU9_9CAUD/137-156 AC A0A858MTU9.1
#=GS E4ZQ93_LEPMJ/262-278 AC E4ZQ93.1
#=GS A0A1Z5KJZ2_FISSO/105-141 AC A0A1Z5KJZ2.1
#=GS A0A420HUQ4_9PEZI/52-69 AC A0A420HUQ4.1
#=GS A0A2U7NF17_9CAUD/180-200 AC A0A2U7NF17.1
#=GS A0A803N0J0_CHEQI/62-96 AC A0A803N0J0.1
#=GS A0A811RM17_9POAL/144-175 AC A0A811RM17.1
#=GS A0A0D3MWQ3_9CAUD/92-113 AC A0A0D3MWQ3.1
#=GS A0A1I6PRQ2_9CAUL/113-134 AC A0A1I6PRQ2.1
#=GS A0A7I4BYJ1_PHYPA/173-202 AC A0A7I4BYJ1.1
#=GS A0A1S2XUW2_CICAR/105-133 AC A0A1S2XUW2.1
#=GS A0A0N9Y9J7_MYCFO/70-106 AC A0A0N9Y9J7.1
#=GS A0A813DT68_POLGL/81-103 AC A0A813DT68.1
#=GS A0A372Q396_9GLOM/27-49 AC A0A372Q396.1
#=GS A7J7R3_PBCVF/94-113 AC A7J7R3.1
#=GS A0A5B9N1K0_9CAUD/116-142 AC A0A5B9N1K0.1
#=GS A0A5B8MEC3_9CHLO/85-106 AC A0A5B8MEC3.1
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