#=GF ID N_formyltrans_C
#=GF AC PF18216.5
#=GF DE N-formyltransferase dimerization C-terminal domain
#=GF AU Smart A;0000-0002-6965-5633
#=GF SE ECOD:EUF02953
#=GF GA 25.80 25.80;
#=GF TC 26.40 26.70;
#=GF NC 25.70 25.00;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP Domain
#=GF RN [1]
#=GF RM 24347283
#=GF RT Three-dimensional structure of a sugar N-formyltransferase from
#=GF RT Francisella tularensis.
#=GF RA Zimmer AL, Thoden JB, Holden HM;
#=GF RL Protein Sci. 2014;23:273-283.
#=GF DR INTERPRO; IPR040660;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC This is the C-terminal domain of N-formyltransferase found in
#=GF CC Francisella tularensis. N-formylated sugars are observed on
#=GF CC O-antigens of pathogenic Gram-negative bacteria. This C-terminal
#=GF CC domain is responsible for dimerization. In particular, the beta
#=GF CC hairpin motif present in the domain helps create a
#=GF CC subunit-subunit interface. The dimeric interface is
#=GF CC characterized by a hydrophobic patch formed by Ile 195, Leu 197,
#=GF CC Val 201, Met 203, Ile 207, Phe 223, Val 231, Val 233, Leu 235,
#=GF CC and Leu 237 from both monomers [1].
#=GF SQ 56
#=GS A0A6L9HHR4_9CLOT/187-238 AC A0A6L9HHR4.1
#=GS A0A6N6N3V0_9DELT/208-257 AC A0A6N6N3V0.1
#=GS A0A6N9NNG6_9FLAO/189-240 AC A0A6N9NNG6.1
#=GS A0A3E0U2H6_9GAMM/187-238 AC A0A3E0U2H6.1
#=GS A0A2S9Q813_9HYPH/145-194 AC A0A2S9Q813.1
#=GS A0A086BMU7_9FLAO/193-245 AC A0A086BMU7.1
#=GS A0A6B0GX21_9EURY/212-262 AC A0A6B0GX21.1
#=GS E3CXE6_9BACT/207-257 AC E3CXE6.1
#=GS A0A521AKQ5_9BACT/193-245 AC A0A521AKQ5.1
#=GS A0A4Y8ZXE6_9SPHN/196-247 AC A0A4Y8ZXE6.1
#=GS A0A086YTN7_9FIRM/23-61 AC A0A086YTN7.1
#=GS H0ADG2_HALSG/168-215 AC H0ADG2.1
#=GS A0A368MYL9_9GAMM/189-240 AC A0A368MYL9.1
#=GS Q82SX5_NITEU/206-259 AC Q82SX5.1
#=GS A0A1E3SMU7_MYCIE/174-225 AC A0A1E3SMU7.1
#=GS A0A1A3NFS8_MYCAS/177-228 AC A0A1A3NFS8.1
#=GS A0A0Q5TR60_9SPHI/204-256 AC A0A0Q5TR60.1
#=GS A0A4Q9VRM7_9HYPH/194-243 AC A0A4Q9VRM7.1
#=GS A0A0Q2QDT6_MYCGO/177-228 AC A0A0Q2QDT6.1
#=GS A0A3M8GD20_9FLAO/198-249 AC A0A3M8GD20.1
#=GS A0A1H5UTC9_9EURY/158-208 AC A0A1H5UTC9.1
#=GS A0A6N0NRR2_9EURY/169-219 AC A0A6N0NRR2.1
#=GS Q5NF01_FRATT/188-239 AC Q5NF01.1
#=GS A0A7D5GH95_9EURY/4-51 AC A0A7D5GH95.1
#=GS A0A8J7W5X0_9EURY/202-253 AC A0A8J7W5X0.1
#=GS T1DUQ3_9HELI/192-234 AC T1DUQ3.1
#=GS F8DAP5_HALXS/174-224 AC F8DAP5.1
#=GS A0A2K8V955_9FLAO/198-248 AC A0A2K8V955.1
#=GS B8FJQ8_DESAL/199-249 AC B8FJQ8.1
#=GS E1QM79_DESB2/199-249 AC E1QM79.1
#=GS A0A858X2A2_9HYPH/199-249 AC A0A858X2A2.1
#=GS A0A5Q0UHI2_9ARCH/170-219 AC A0A5Q0UHI2.1
#=GS A0A0S2HZU7_9BACT/203-255 AC A0A0S2HZU7.1
#=GS A0A8J8C9A5_9EURY/170-220 AC A0A8J8C9A5.1
#=GS A0A1I0MTP8_9EURY/171-221 AC A0A1I0MTP8.1
#=GS A0A1A2G8E6_9MYCO/77-128 AC A0A1A2G8E6.1
#=GS A0A329ZC25_9HELI/184-235 AC A0A329ZC25.1
#=GS SUGFT_MYCTU/177-228 AC P9WKZ3.1
#=GS R9KZ25_9FIRM/190-241 AC R9KZ25.1
#=GS A0A3D8I0T0_9HELI/186-237 AC A0A3D8I0T0.1
#=GS A0A1H6YH12_9EURY/170-220 AC A0A1H6YH12.1
#=GS A0A5B9P5Q8_9BACT/199-249 AC A0A5B9P5Q8.1
#=GS A0A1X2CIL8_9MYCO/177-228 AC A0A1X2CIL8.1
#=GS A0A6J4WWB0_9DELT/168-218 AC A0A6J4WWB0.1
#=GS A0A368L3Q1_9BURK/223-272 AC A0A368L3Q1.1
#=GS A0A7D5H6V7_9EURY/174-224 AC A0A7D5H6V7.1
#=GS A0A2W1KB60_9FLAO/198-248 AC A0A2W1KB60.1
#=GS A0A399SHN2_9BACT/190-241 AC A0A399SHN2.1
#=GS A0A6A9SIM7_9EURY/174-224 AC A0A6A9SIM7.1
#=GS A0A4R8DQ66_9BACT/198-249 AC A0A4R8DQ66.1
#=GS K6XJK5_9ALTE/192-242 AC K6XJK5.1
#=GS E4TQN2_MARTH/188-239 AC E4TQN2.1
#=GS A0A7U8TRQ7_MYCTX/177-228 AC A0A7U8TRQ7.1
#=GS A0A7I7MTA4_9MYCO/174-225 AC A0A7I7MTA4.1
#=GS A0A4Y6IDB5_9GAMM/187-237 AC A0A4Y6IDB5.1
#=GS A0A7U8TX00_MYCTX/177-228 AC A0A7U8TX00.1
A0A6L9HHR4_9CLOT/187-238 ......DFAALCRLDLDQRGTFGEFMRMLRAVT.FEG.Y.DN.AFFYD.QDGGKIYVEIRLRK..........
A0A6N6N3V0_9DELT/208-257 ....el--ENASELRRQQVYSWRQLLNLIRART.FRP.H.PA.CYFFQ.N-GKKVFIR-----snvt......
A0A6N9NNG6_9FLAO/189-240 ......DFIDLCELELDEKVTYREVINRLRALT.HGD.Y.KN.AYFFD.EEGRKVYVSVNLE-l.........
A0A3E0U2H6_9GAMM/187-238 ......DFKALCELDLNQKGTLQEHLNLLRALT.HGD.Y.AN.AHYIN.DEGEKVFVKIELAK..........
A0A2S9Q813_9HYPH/145-194 ..ldpk-----SQIDLDAPTTARELFNRLRART.FPP.H.RG.CRFTD.A-NNTYEVRIEITK..........
A0A086BMU7_9FLAO/193-245 ......DFNNLCKIDLQEQTTTGQFINKLRALS.HKS.F.KN.AYFIDpKSGKKVFISINIE-a.........
A0A6B0GX21_9EURY/212-262 ....ef--VDLCELDPDEELTTKELLDRLRALT.FPP.F.DN.ARIDV.D-GETYYVEVSITH..........
E3CXE6_9BACT/207-257 ......DFRNMLEIDTKKTVVVGDFIKKLRAFT.FPP.Y.KN.LYFQE.N-GRRYYVEVVI--se........
A0A521AKQ5_9BACT/193-245 .....a-YKNLCEINLNETVTYGDAINRLRALS.HGK.Y.SN.AYFIDeKTKEKIFLNIVLK-q.........
A0A4Y8ZXE6_9SPHN/196-247 ......DFRELCALDLDQRGTLREHLALLRALT.HPP.F.KN.AYYDD.DAGNRIFVALDV--ev........
A0A086YTN7_9FIRM/23-61 ......DTDKIDKIEPDKFYKAIDLINIIRART.FPP.Y.KG.AYL--.--------------eym.......
H0ADG2_HALSG/168-215 ......DLDEISNLDLEKEMTLREAINLLKGLT.FGD.K.KL.ASIDE.E----YFVGVNIEK..........
A0A368MYL9_9GAMM/189-240 ......DFNALRSLDLSSEGSLGEHIDLLRALT.HGD.F.NN.AYFLD.ENSEKIYIKISLNK..........
Q82SX5_NITEU/206-259 .....k-FEKTCLIDLNKSYQGVEFFNLLRGLAfFED.S.KN.AYVIDdESGQKIYISLNLR-e.........
A0A1E3SMU7_MYCIE/174-225 ......DFAALRELDLTERGTFGAFLNRLRALT.HDE.Y.RN.AWFVD.ESGRKVFVRVVL--ep........
A0A1A3NFS8_MYCAS/177-228 ......DFARLRQLDLDEQGTFGQFLNRLRALT.HDE.F.RN.AWFVD.DSGRKVFVRIVLE-p.........
A0A0Q5TR60_9SPHI/204-256 ......DFKELCKLNLEEKLTMLEAINRLRALS.HGE.L.NN.AYFIDpDTGQKIFVTLNLKY..........
A0A4Q9VRM7_9HYPH/194-243 .lepas------LIDLDSAYRARDLFDLLRART.FTG.Y.PS.ARFVDgD--ETYEVSISIT-r.........
A0A0Q2QDT6_MYCGO/177-228 ......DFERLRQLDLDEHGSFGQFLDRLRALT.HDE.F.RN.AWFVD.SSGRKVFVRVVL--ep........
A0A3M8GD20_9FLAO/198-249 ......DLFKINEISLEENIRAGDLIDKLRALT.TNR.V.DEfAYFIH.N-SKKYALEIKIT-e.........
A0A1H5UTC9_9EURY/158-208 .....e-FDDLCELNPDEEVRVKDFLDRLRALT.YPP.Y.DN.AEIEV.D-GETYYIEVDITK..........
A0A6N0NRR2_9EURY/169-219 ...emd---DIVEIDRDEKVRAGELIDRLRALT.FPP.H.RN.AFFTE.K-GEKYFIEVEIT-p.........
Q5NF01_FRATT/188-239 ......DYKNMCEIDLDKIVTMREAIDYLRAMT.HPP.Y.KN.SYFID.EHGNKVFVALELEK..........
A0A7D5GH95_9EURY/4-51 ......DFFDLCELGIDKTVAVHVFLNRLHALS.FPP.F.DN.NGIEE.G-GETYSVNI----w.........
A0A8J7W5X0_9EURY/202-253 ......DIHSIQKIDVNEPIKPKALINVLRALT.TNNiH.EA.AYFED.N-GNRYRVQISI--ik........
T1DUQ3_9HELI/192-234 keidsa-----STIDLNKSYIARDLLNLLRAKS.FKP.H.KG.CVFK-.--------------asngg.....
F8DAP5_HALXS/174-224 ......DFKELCRLDPDETVRVKEFLDRLRALT.FPP.Y.DN.AEIEV.D-GETYYVDIDITK..........
A0A2K8V955_9FLAO/198-248 ......DLESIQEINVDKNYKGKDIINLLRGLT.TNNiK.ES.AYFVE.N-GKKQYIQINI--i.........
B8FJQ8_DESAL/199-249 ......DLKTIQEIKPNKLYTARELVDVIRART.FEP.H.PG.AHMVV.D-GKKVFMRLELYY..........
E1QM79_DESB2/199-249 ......DVKKIDHIDLDKSYNARELIDILRART.FPP.H.AG.AYFVE.N-GRRVYVSLQLSH..........
A0A858X2A2_9HYPH/199-249 ......DLAELDEIDRARTYQARDLLNLLRART.YPP.Y.PA.AYDIE.S-GERRYLRVALS-e.........
A0A5Q0UHI2_9ARCH/170-219 ......DLEDERRIKLNEETSKEDFIDELRALT.YPP.H.RN.AYIER.N-GKKYHLELDI--v.........
A0A0S2HZU7_9BACT/203-255 ......DYEESNYIELDKKVTFGEVIDYLRGKT.FQD.K.SP.AFYIDrNTNEKIFVSIKFTK..........
A0A8J8C9A5_9EURY/170-220 .....e-FSELCELDPEAEYTVRELLDRLRALT.FPP.F.DN.AYVDV.D-GERYYLELSIT-p.........
A0A1I0MTP8_9EURY/171-221 ...efg---AVCELNLSEEARIGDVIDTLRALT.FPP.Y.YN.AYFEQ.D-GERYYVRVSI--ep........
A0A1A2G8E6_9MYCO/77-128 ..lepa-----SVIDLDAPTTARDLLNRLRART.FLP.H.PA.CRFYDgD---DVF-------evrvtidklr
A0A329ZC25_9HELI/184-235 ......DYKKICHIDLDEILSMRDAINRFRALT.HPP.H.KN.AYFLD.SNGEKIYIEITLTK..........
SUGFT_MYCTU/177-228 ......DFEQLRRLDLNERGTFGHFLNRLRALT.HDD.F.RN.AWFVD.ASGRKVFVRVVL--ep........
R9KZ25_9FIRM/190-241 ......DFERLCHIDMGQEATYGEVIDLLRAMT.FDT.Y.DN.AYFVD.SKGNKIYVSVNLK-r.........
A0A3D8I0T0_9HELI/186-237 ......DFKNLCKINLDKILTMQEAIDYLRALS.HKP.Y.KN.AYFID.KNGDKIFVSLKLQK..........
A0A1H6YH12_9EURY/170-220 ......DFVDLCRIDPEQTYEAKELIDILRALS.FPP.F.DN.AYIEI.D-GEKQYIEIEVT-p.........
A0A5B9P5Q8_9BACT/199-249 ......DTANIDRIDLDATVRAGDLIDVLRART.FPP.H.RG.AYFEV.D-GQRYFLELKIEK..........
A0A1X2CIL8_9MYCO/177-228 ......DFERLRQLDLNERGTFGQFLNRLRALT.HDD.F.RN.AWFVD.ASGRKVFVRVVL--ep........
A0A6J4WWB0_9DELT/168-218 ......DFKKLRKIDPQSTVRAIDFINFLRAMT.FPP.F.NN.AYIEQ.N-GKKYFVKIEIT-p.........
A0A368L3Q1_9BURK/223-272 ..ldaa-----SEIKLDHPYPARELLNRIRART.FPG.H.PG.CWFTD.D-GQTYEIQLTIRK..........
A0A7D5H6V7_9EURY/174-224 .....e-FDGLCELDPEETVQVKPFIDRLRALT.YPP.Y.DN.ARIEV.D-GETYTVEVDITK..........
A0A2W1KB60_9FLAO/198-248 ......DLEKVKELKLEEKYTAREILDKIRALTtNKD.S.EL.AFFVE.D-GKKVGVRVEF--i.........
A0A399SHN2_9BACT/190-241 ......DFNNFLLLDLEQKGTMEEILDKLRALT.HGT.Y.KN.AYYIDkQTGKKVFVSLQL--i.........
A0A6A9SIM7_9EURY/174-224 ......DFKDLCHLDPHEEVKVKELLNRLRALT.FPP.Y.DN.AEIEI.D-GDTYYIEIDIE-r.........
A0A4R8DQ66_9BACT/198-249 ....dl--GLLQPLDPEENVRTGDLLKRLRALT.TNK.TeEA.AYLIE.D-GRKYFIQVTM--tp........
K6XJK5_9ALTE/192-242 ....el--EQASQINLEKQYRARDLLNLLRART.FSG.H.PS.CWFVD.D-GSKYEVTIKIKK..........
E4TQN2_MARTH/188-239 ......DFKNLSEIDLDKKVSFREALDFLRAMT.HGD.Y.KN.AYFID.KKGDKVFVSIKLNK..........
A0A7U8TRQ7_MYCTX/177-228 ......DFEQLRRLDLNERGTFGHFLNRLRALT.HDD.F.RN.AWFVD.ASGRKVFVRVVL--ep........
A0A7I7MTA4_9MYCO/174-225 ......DFERLRHLDLNEHGTFGDFLNRLRALT.HDG.Y.RN.AWFVD.ASGRKVFVRVVL--ep........
A0A4Y6IDB5_9GAMM/187-237 ......DFNELCNLNLEHVGTLKEHIELLRALS.HGD.F.KN.AYFVDaD-EIKRYIKVDI--m.........
A0A7U8TX00_MYCTX/177-228 ......DFEQLRRLDLNERGTFGHFLNRLRALT.HDD.F.RN.AWFVD.ASGRKVFVRVVL--ep........
#=GC seq_cons ......DapplsclDL-cpssht-hlshLRALT.ass.a.cN.AaFh-.s.GcKhalplsl............
//
