#=GF ID Ndc10_N
#=GF AC PF21400.1
#=GF DE Ndc10 N-terminal domain
#=GF AU Bateman A;0000-0002-6982-4660
#=GF SE ECOD:EF24743
#=GF GA 23.80 23.80;
#=GF TC 25.60 24.30;
#=GF NC 23.30 21.40;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP Domain
#=GF CL CL0469
#=GF RC Paper describing PDB structure 3sqi
#=GF RN [1]
#=GF RM 22139014
#=GF RT Ndc10 is a platform for inner kinetochore assembly in budding
#=GF RT yeast.
#=GF RA Cho US, Harrison SC;
#=GF RL Nat Struct Mol Biol. 2011;19:48-55.
#=GF RC Paper describing PDB structure 6p7w
#=GF RN [2]
#=GF RM 31425683
#=GF RT Structure of the Centromere Binding Factor 3 Complex from
#=GF RT Kluyveromyces lactis.
#=GF RA Lee PD, Wei H, Tan D, Harrison SC;
#=GF RL J Mol Biol. 2019;431:4444-4454.
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC Kinetochores link centromeric DNA to spindle microtubules and
#=GF CC ensure faithful chromosome segregation during mitosis. In
#=GF CC point-centromere yeasts, the CBF3 complex
#=GF CC Skp1-Ctf13-(Cep3)(2)-(Ndc10)recognizes a conserved centromeric
#=GF CC DNA element through contacts made by Cep3 and Ndc10. This entry
#=GF CC represents the N-terminal domain of Ndc10.
#=GF SQ 26
#=GS G8ZU62_TORDC/4-119 AC G8ZU62.1
#=GS A0A1X7QY22_9SACH/12-121 AC A0A1X7QY22.1
#=GS G0WGD3_NAUDC/7-136 AC G0WGD3.1
#=GS A0A1G4MGK1_LACFM/4-116 AC A0A1G4MGK1.1
#=GS G0VF78_NAUCC/6-144 AC G0VF78.1
#=GS A0A1S7HT93_9SACH/57-152 AC A0A1S7HT93.1
#=GS A0A1G4K2R2_9SACH/63-182 AC A0A1G4K2R2.1
#=GS A0A4C2DYN4_9SACH/1-118 AC A0A4C2DYN4.1
#=GS A0A7H9B072_ZYGMR/9-143 AC A0A7H9B072.1
#=GS A0A376B606_9ASCO/7-164 AC A0A376B606.1
#=GS CBF3A_YEAST/27-158 AC P32504.1
#=GS I2H337_TETBL/3-125 AC I2H337.1
#=GS Q6FQ06_CANGA/5-118 AC Q6FQ06.1
#=GS A7TRC9_VANPO/19-150 AC A7TRC9.1
#=GS A0A1E4T2B3_9ASCO/70-159 AC A0A1E4T2B3.1
#=GS A0A1E5R0D0_9ASCO/12-143 AC A0A1E5R0D0.1
#=GS A0A1G4JW73_9SACH/4-116 AC A0A1G4JW73.1
#=GS A0A1S7H9W1_9SACH/52-147 AC A0A1S7H9W1.1
#=GS J7R158_KAZNA/7-128 AC J7R158.1
#=GS H2AS47_KAZAF/8-121 AC H2AS47.1
#=GS G8BSZ7_TETPH/9-143 AC G8BSZ7.1
#=GS A0A0C7MSH5_9SACH/4-116 AC A0A0C7MSH5.1
#=GS G8JN09_ERECY/2-102 AC G8JN09.1
#=GS Q753I9_ASHGO/2-103 AC Q753I9.1
#=GS C5DLN8_LACTC/12-125 AC C5DLN8.1
#=GS A0A7H9HSL5_9SACH/4-118 AC A0A7H9HSL5.1
G8ZU62_TORDC/4-119 ............ESQVRKLVD..SVSPRTAHQYKSYGDKYIRWLRDTGILQN..EDA--...................GEVLYRDLPLSAQLVHWFLIDTLVRNG.......................GNETEDEFKI.PTLKKVISGLKFLHKLCLIHG......N-.KLVFDEK...YLENVIKLH....................
A0A1X7QY22_9SACH/12-121 ...........n-DQLTALSE..SLPTRTLHQYKTFNTQYIQWLIKNNISEN..-----...................-NTTYDSLPLSSILIHKFLLDTIITKT.......................---KYSNKLL.PLLKSYINSFFFLQKICKIHG......NK.QNDIDTL...YLDEIINLH....................
G0WGD3_NAUDC/7-136 ...........s-SNVQFLLG..SISPKIQLQYKYHFAQYINWCRNRNLLDV.sQ-QQQqqq............qpvtDEDIYRRLPISCFLIHWFIIDTFIINV.......................PTSNSKLPTS.EEIEKIIKSLKFLDKLCHVAK.....gNI.EYTIDPRvesYLNSIPS--iy..................
A0A1G4MGK1_LACFM/4-116 ...........e-PQIKALVE..TLAPRTAHQYKLYQSKYIEWCRSHGLVRS..PPA--...................-SGPYADVIVTASLVHWFVLAHYVCAA.......................----DAQFSA.SALRKLVSALKFLHRLCRVYD......PAyPYRLDGD...YLEAVVRLH....................
G0VF78_NAUCC/6-144 ...........d-ARIQSLLS..SVSPRTLFQYKTNYSRYISWCESKQLIPS.sENIND..................dQEPLFETLPISARLFHCFIIDAYFGSNtnvsqnkde.....adfeqltisMTESNGATNI.KLLKKTIHSLKFLFKLCQIYN......EQ.LPPLDES...YLHGIIDLH....................
A0A1S7HT93_9SACH/57-152 ...........m-DQLRSLVD..SLSPRTAHQYRSYCKRYVGWLVERGLLES..EPDE-...................-LVHYHSLPLNNALVHWHLIETAQ---.......................--------AL.PSLRKAISSLKFLSKLCAVNG......--.-------...---------gagsfset............
A0A1G4K2R2_9SACH/63-182 ............EQQLRALAD..TLAPRTAQQYKLYQTKYIQWCRAQGLVRT..PTAQTqq...............tqTNNVYADVVVTSPLAHWFILANYVCAP.......................----NASLGP.SALRKIFSALRLLYRICKIYD......PAyPFVLNNE...YLEAVVRLH....................
A0A4C2DYN4_9SACH/1-118 ...........m-EEVRKLVD..ALSPRTAHQYRSYCKRYVEWLVQKGLIER..ELREEt.................fDTVQYAKLPISTQLVHWHIIDTMGIGS.......................---------L.PSIRKCISSLKFLDKLCSMHRgnghgsAT.VTKLDEK...YLENITRV-r...................
A0A7H9B072_ZYGMR/9-143 ...........g-TQVRDLVD..SLSPRTAHQYKSYNAKYVQWLRGRKIIGS..-DAE-...................ASVLYRELPLSAHLVHWFLLDTLILESghgqggggd....krgdkrgdedGDDDKDDFKI.ATLKKMVSSLKFLNKLCAIHG......N-.SSKIDDK...YVENVTKLH....................
A0A376B606_9ASCO/7-164 ...........e-LRVKELIS..KLNPRTVYQYKLYQSKYIKWYKNYIVKDN.tTNDNK...................KSNYYADIKVNAPLIHLYILHLYETSKteeeeegegeinaeknknttdlmDHNSDDNINI.ATYRKIISSLNLLNKIIVIHK......NE.KEQFEEQkeeR--------eenanatvgeeylenvikly
CBF3A_YEAST/27-158 ...........e-DRFQELVD..SLKPRTAHQYKTYYTKYIQWCQLNQIIPT..PEDNS..................vNSVPYKDLPISAELIHWFLLDTLITDDkpgekr...........eetedlDEEEENSFKI.ATLKKIIGSLNFLSKLCKVHE......NP.NANIDTK...YLESVTKLH....................
I2H337_TETBL/3-125 ..........va--KEKELFN..TLSPRALNQYKSYYTKFIHWSIKKKHFID..QDLNLqd..............dsdLVSIYKHIDVSPYRLHWFIIDTFYKQGe.....................eDNAIYDFPAT.GTIRKIIVALRFFIKLIKIYD......NS.S---AEK...YFPDQV---rde.................
Q6FQ06_CANGA/5-118 ...........d-NEIRKLME..SVAPIKVHQYKSYYMKYIEWCEQKELLSF..ESN--...................SSIPYENVPLLPQLVHLFLLECVIKWP.......................----IVASDV.NELQIYIESFRFLKKLCDIHSe....vDP.NSEFDD-...YITDVLELH....................
A7TRC9_VANPO/19-150 ...........d-LQVTNLMG..SLSARTANQYKSYYTKYIKWCHSKGFILD..TED--...................TEFVYKHLPVSSNLFHWFLMDDFITNTdaadsh..........stiessnLDHESVSLKI.GTLKKIVSSLKFLAKICSIHKe....gTE.DVHIDEK...YLESIIRSH....................
A0A1E4T2B3_9ASCO/70-159 vsrihsfavtlr---------..--NERTQKSYKSEERKYCEWCRSHNKCQA..-----...................-NTPDREVPLTPMLIIGYLEASVAKRT.......................-TKKGKLVQM.GVIDKAKTALKHLLK------......--.-------...---------e...................
A0A1E5R0D0_9ASCO/12-143 ...........d-QKIQQFVEaqRLPAKTLYQYKLYHLKYVAWYKKVYHGTTsgEADDKavdnkavdnkavdnkavdnNAVDYANVDIDAYKICLFLIHCLKDTL.......................--------NIdAIMETIVPALEFLYKLATLAT......GD.QDT----...---------iahvlaaknv..........
A0A1G4JW73_9SACH/4-116 ...........e-LQIKALVD..TLAPRTAHQYKLYHTKYLQWCRENRLVRR..AET--...................-NHPYKDVIVTAPLVHWFILANFVCKE.......................----DAQFSV.SVLRKMISAFKFLHRICKAYE......PDySYDLDHD...YLEGVARLH....................
A0A1S7H9W1_9SACH/52-147 ...........m-DQVRSLVD..SLSPRTAHQYRSYCKRYVGWLVERGLLES..EPDE-...................-LVHYHSLPLNNALVHWHLIETAQ---.......................--------AL.PSLRKAISSLKFLSKLCAVNG......--.-------...---------gagsfset............
J7R158_KAZNA/7-128 ............QQKLKLLEG..SVSPRARYLFRNYFLQYVKWCQKHGLLQD..EDLDS...................NREVYSNLPLYNAVIHRFIIDTVVLQN......................gNDSGTNEIDT.EAFGMIVQALQFYGKICSLYG......NE.RMDLNASl.pYFVNVNLLH....................
H2AS47_KAZAF/8-121 ............QSQVRKLSD..TLSPRILHQYKTYYTQYIHWCQYNKVLVT..ANDN-...................DPLPYKDVPVSAQLIHRFLLDTLITNT.......................----DEIFSL.QKLKEMINSLRFLYKLCAIHG......NE.NDSLDDT...YLDSVVHLH....................
G8BSZ7_TETPH/9-143 ...........n-AKAQQLFD..ALTERTKHQYKSYYGRYIKWCEENKLISK..-SLN-...................ENEIFEKLPLSSMLFHCFLLDLYISKDsndnndki......tttnddkenLIAENIGVKL.STLKKIISSLKFLVRVCTVYN......NEnVSKVDDK...YLENITKLH....................
A0A0C7MSH5_9SACH/4-116 ...........e-LQIKALVD..TLAPRTAHQYKLYHTKFLQWCRDNQLVRT..PVA--...................-DHPYKDVIVTATLVHWFVLSKFVCAK.......................----DSQLTV.SVLRKMISAFKFLHRVCKAYE......PEyPYELDND...YLEDVARLH....................
G8JN09_ERECY/2-102 ...........e-SQLDKVYA..RFSSRDVHRYKSYVRRYLDWCEEHELDVG..NGSN-...................-----GEVWASAKRVHWFLQDIWRAGG.......................-------SGV.GELKSIVNCLRLVSKE--MG-......--.GESMDKE...YLDNVIRLY....................
Q753I9_ASHGO/2-103 .........elq---LDRAFS..RFSSRDVHRYKSYVKQYLEWCRERGLDVE..-----...................-SCSAAELWGSARRLHWFLQSKWG---.......................----SGIESV.AEMKSVVNCIQLLGRELAT--......--.GAQLDKA...YIDNVVRLH....................
C5DLN8_LACTC/12-125 ..........hl--HIKALVD..TLAPRTAHQYKLYHTKFIQWCRDNKLLRR..DPG--...................ADHPYRDIVVTATLVHCFVLSQYVCVS.......................----DSQFSA.SVLRKMISAFKFLHRVCCAYE......PDyPYELDHD...YLEAVARLH....................
A0A7H9HSL5_9SACH/4-118 ...........e-EELRKLVD..SVSPRTAHQYRSYGDRFVRWLREREVLGR..GDVE-...................EEVLYRELPFSSQLVHWFLVETVVRDR.......................--DDGDEGRV.ASVRKVVSSLKFLYRVCVVHG......N-.KSKLDEK...YLENVVRLY....................
#=GC seq_cons ...........p.tpl+pLh-..oLuPRTsHQYKoYhs+YlpWCcpptllps..tssp....................tss.YcclPloutLlHWFll-shlpps...........................psthsl.usL+KhIsuL+FLtKlCplat......s..t.plDpp...YL-slhcLH....................
//
