#=GF ID Ndufs5
#=GF AC PF10200.13
#=GF DE NADH:ubiquinone oxidoreductase, NDUFS5-15kDa
#=GF AU KOGs;
#=GF AU Finn RD;0000-0001-8626-2148
#=GF AU Coggill P;0000-0001-5731-1588
#=GF SE KOGs (KOG4110)
#=GF GA 21.20 21.20;
#=GF TC 21.20 21.20;
#=GF NC 21.10 21.10;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP Family
#=GF WK NADH_dehydrogenase_(ubiquinone)
#=GF CL CL0351
#=GF RN [1]
#=GF RM 10070614
#=GF RT The human NADH: ubiquinone oxidoreductase NDUFS5 (15 kDa)
#=GF RT subunit: cDNA cloning, chromosomal localization, tissue
#=GF RT distribution and the absence of mutations in isolated complex
#=GF RT I-deficient patients.
#=GF RA Loeffen J, Smeets R, Smeitink J, Triepels R, Sengers R, Trijbels
#=GF RA F, van den Heuvel L;
#=GF RL J Inherit Metab Dis. 1999;22:19-28.
#=GF DR INTERPRO; IPR019342;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This is a family of short, approximately 105 amino acid residue,
#=GF CC proteins which form part of NADH:ubiquinone oxidoreductase
#=GF CC complex I. Complex I is the first multisubunit inner membrane
#=GF CC protein complex of the mitochondrial electron transport chain
#=GF CC and it transfers two electrons from NADH to ubiquinone. The
#=GF CC protein carries four highly conserved cysteine residues but
#=GF CC these do not appear to be in a configuration which would favour
#=GF CC metal binding so the exact function of the protein is uncertain
#=GF CC [1].
#=GF SQ 1252
#=GS A0A7L3LAY7_9CHAR/1-72 AC A0A7L3LAY7.1
#=GS A0A2G3B1P6_CAPCH/2-73 AC A0A2G3B1P6.1
#=GS A0A7K6HVG1_9PASS/1-96 AC A0A7K6HVG1.1
#=GS A0A093XJ88_9PEZI/2-75 AC A0A093XJ88.1
#=GS A0A0L8I7D3_OCTBM/9-69 AC A0A0L8I7D3.1
#=GS A0A445CMI5_ARAHY/2-73 AC A0A445CMI5.1
#=GS A0A1E4RQK4_9ASCO/1-75 AC A0A1E4RQK4.1
#=GS A0A834W5F0_9FABA/2-72 AC A0A834W5F0.1
#=GS A0A672Z9V1_9TELE/1-96 AC A0A672Z9V1.1
#=GS A0A2Y9F0T9_PHYMC/1-96 AC A0A2Y9F0T9.1
#=GS A0A6A1URV3_9ROSI/2-74 AC A0A6A1URV3.1
#=GS A0A0V0URZ0_9BILA/23-97 AC A0A0V0URZ0.1
#=GS W9VPT2_9EURO/2-75 AC W9VPT2.1
#=GS A0A5P1FMP0_ASPOF/1-73 AC A0A5P1FMP0.1
#=GS M1CSQ3_SOLTU/1-73 AC M1CSQ3.1
#=GS A0A453RRW3_AEGTS/2-73 AC A0A453RRW3.1
#=GS A0A8C8BNH8_9STRI/132-227 AC A0A8C8BNH8.1
#=GS A0A166QBK7_9PEZI/22-98 AC A0A166QBK7.1
#=GS A0A671N9F0_9TELE/1-96 AC A0A671N9F0.1
#=GS A0A1G4ATC8_9PEZI/1-75 AC A0A1G4ATC8.1
#=GS A0A8D2JKP7_VARKO/1-96 AC A0A8D2JKP7.1
#=GS A0A2B7YII6_9EURO/2-77 AC A0A2B7YII6.1
#=GS B1ARW4_MOUSE/1-91 AC B1ARW4.1
#=GS G5BP30_HETGA/1-96 AC G5BP30.1
#=GS A0A7J8KDA5_ROUAE/1-96 AC A0A7J8KDA5.1
#=GS A0A022RG47_ERYGU/15-107 AC A0A022RG47.1
#=GS A0A8C8S749_9SAUR/1-96 AC A0A8C8S749.1
#=GS A0A7K6Q9T1_9PASS/1-96 AC A0A7K6Q9T1.1
#=GS A0A3L6PLG0_PANMI/2-73 AC A0A3L6PLG0.1
#=GS A0A7L2Q9I8_9PASS/1-72 AC A0A7L2Q9I8.1
#=GS A0A8J4UQ76_CLAMG/14-109 AC A0A8J4UQ76.1
#=GS A0A7K6NF97_PEDTO/1-67 AC A0A7K6NF97.1
#=GS A0A167D784_9PEZI/37-113 AC A0A167D784.1
#=GS A0A4D8XZ82_SALSN/2-71 AC A0A4D8XZ82.1
#=GS N4V7L9_COLOR/1-74 AC N4V7L9.1
#=GS A0A4S2MFN6_OPIFE/76-162 AC A0A4S2MFN6.1
#=GS A0A8J5D189_CHIOP/42-120 AC A0A8J5D189.1
#=GS R7V440_CAPTE/21-101 AC R7V440.1
#=GS A0A7J8TID4_GOSDV/2-73 AC A0A7J8TID4.1
#=GS A0A8C7AME5_NEOVI/1-96 AC A0A8C7AME5.1
#=GS A0A7J8FA16_MOLMO/21-116 AC A0A7J8FA16.1
#=GS Q7Q1E9_ANOGA/11-96 AC Q7Q1E9.2
#=GS G0P0Z4_CAEBE/23-100 AC G0P0Z4.1
#=GS A0A8I5NDW7_PAPAN/4-97 AC A0A8I5NDW7.1
#=GS L9KXI1_TUPCH/1-94 AC L9KXI1.1
#=GS Q5DDL6_SCHJA/75-157 AC Q5DDL6.1
#=GS A0A7L0VBL7_9PASE/1-96 AC A0A7L0VBL7.1
#=GS A0A484K2D8_9ASTE/2-76 AC A0A484K2D8.1
#=GS A0A4E0RK81_FASHE/71-155 AC A0A4E0RK81.1
#=GS A0A8I6TH66_CIMLE/7-89 AC A0A8I6TH66.1
#=GS A0A452R6W0_URSAM/13-108 AC A0A452R6W0.1
#=GS A0A7R9L6C5_9ACAR/26-110 AC A0A7R9L6C5.1
#=GS A0A4X2K198_VOMUR/1-96 AC A0A4X2K198.1
#=GS A0A1U7TRK7_CARSF/1-96 AC A0A1U7TRK7.1
#=GS A0A8C3CSG8_CAIMO/1-96 AC A0A8C3CSG8.1
#=GS A0A6G0YGI0_APHCR/14-91 AC A0A6G0YGI0.1
#=GS A0A6P3RDI5_PTEVA/1-96 AC A0A6P3RDI5.1
#=GS A0A0B0N575_GOSAR/2-73 AC A0A0B0N575.1
#=GS A0A7L3GBQ5_9AVES/1-96 AC A0A7L3GBQ5.1
#=GS A0A328D9E8_9ASTE/2-76 AC A0A328D9E8.1
#=GS A0A388MA24_CHABU/4-74 AC A0A388MA24.1
#=GS A0A8J6FZI6_MICOH/1-96 AC A0A8J6FZI6.1
#=GS A0A7L2F673_QUIME/1-96 AC A0A7L2F673.1
#=GS A0A5J9SZY2_9POAL/2-73 AC A0A5J9SZY2.1
#=GS F7EJW4_MACMU/1-96 AC F7EJW4.1
#=GS A0A4W5L3X6_9TELE/1-96 AC A0A4W5L3X6.1
#=GS A0A7L1U5G7_PHANI/1-96 AC A0A7L1U5G7.1
#=GS W1P2W7_AMBTC/1-73 AC W1P2W7.1
#=GS A0A3M6UJK8_POCDA/5-76 AC A0A3M6UJK8.1
#=GS A0A498LDC1_LABRO/1-96 AC A0A498LDC1.1
#=GS A0A5E4NKN2_9HEMI/12-94 AC A0A5E4NKN2.1
#=GS A0A7L1GJX1_9PICI/1-96 AC A0A7L1GJX1.1
#=GS A0A3Q3EBJ5_9LABR/1-96 AC A0A3Q3EBJ5.1
#=GS A0A2Y9DDB4_TRIMA/1-96 AC A0A2Y9DDB4.1
#=GS A0A3Q2VSN2_HAPBU/1-96 AC A0A3Q2VSN2.1
#=GS A0A7L0GGT2_HERCA/1-96 AC A0A7L0GGT2.1
#=GS M3X8I4_FELCA/73-168 AC M3X8I4.2
#=GS A0A8D2FJY9_THEGE/1-96 AC A0A8D2FJY9.1
#=GS A0A8H6XG68_9AGAR/2-74 AC A0A8H6XG68.1
#=GS A0A7L3XPI3_9AVES/1-96 AC A0A7L3XPI3.1
#=GS A0A2A2LCR8_9BILA/23-99 AC A0A2A2LCR8.1
#=GS A0A8H6KQT6_9PEZI/1-76 AC A0A8H6KQT6.1
#=GS A0A7K7SH52_9TYRA/1-96 AC A0A7K7SH52.1
#=GS A0A428SQE2_9HYPO/3-72 AC A0A428SQE2.1
#=GS A0A158NT31_ATTCE/25-106 AC A0A158NT31.1
#=GS A0A1U8KHZ4_GOSHI/2-73 AC A0A1U8KHZ4.1
#=GS A0A2R6QDR0_ACTCC/1-73 AC A0A2R6QDR0.1
#=GS A0A8C7ER16_NEOVI/1-96 AC A0A8C7ER16.1
#=GS A0A4Y9Z9W1_9AGAM/2-76 AC A0A4Y9Z9W1.1
#=GS G7KRW9_MEDTR/3-71 AC G7KRW9.1
#=GS A0A8C0G2D4_CHEAB/1-96 AC A0A8C0G2D4.1
#=GS A0A7K8SME5_9AVES/1-96 AC A0A7K8SME5.1
#=GS A0A3Q1AHH5_AMPOC/1-96 AC A0A3Q1AHH5.1
#=GS A0A6I9WT74_9HYME/26-105 AC A0A6I9WT74.1
#=GS A0A8J5YCF9_9ROSI/2-74 AC A0A8J5YCF9.1
#=GS A0A834NGB1_VESVU/7-100 AC A0A834NGB1.1
#=GS NDUS5_HUMAN/1-96 AC O43920.3
#=GS A0A5N4DD92_CAMDR/1-96 AC A0A5N4DD92.1
#=GS A0A7L1J4V0_SMUAF/1-96 AC A0A7L1J4V0.1
#=GS A0A093XGM5_9PEZI/2-75 AC A0A093XGM5.1
#=GS A0A183DYG1_9BILA/23-103 AC A0A183DYG1.1
#=GS A0A669BUV3_ORENI/1-96 AC A0A669BUV3.1
#=GS S7R6Y8_GLOTA/3-77 AC S7R6Y8.1
#=GS E2AYL7_CAMFO/23-104 AC E2AYL7.1
#=GS A0A7K5G6V3_9AVES/1-96 AC A0A7K5G6V3.1
#=GS A0A091MB74_CATAU/1-22 AC A0A091MB74.1
#=GS A0A7L1HIF7_9CHAR/1-96 AC A0A7L1HIF7.1
#=GS A0A2V1CGF0_9HELO/2-75 AC A0A2V1CGF0.1
#=GS A0A7K6CPC6_9PASS/1-96 AC A0A7K6CPC6.1
#=GS A0A091HY63_CALAN/1-22 AC A0A091HY63.1
#=GS A0A2K6B517_MACNE/1-96 AC A0A2K6B517.1
#=GS A0A3M0IR92_HIRRU/1-79 AC A0A3M0IR92.1
#=GS A0A6P4F225_DRORH/11-89 AC A0A6P4F225.1
#=GS A0A0R3PIC8_ANGCS/27-97 AC A0A0R3PIC8.1
#=GS A0A835QKV9_VANPL/2-73 AC A0A835QKV9.1
#=GS A0A2H3IVZ1_9EURO/3-74 AC A0A2H3IVZ1.1
#=GS A0A7L3T728_RISTR/1-97 AC A0A7L3T728.1
#=GS A0A2K6NKB3_RHIRO/1-96 AC A0A2K6NKB3.1
#=GS A0A663MZ86_ATHCN/100-131 AC A0A663MZ86.1
#=GS A0A0K9R7I7_SPIOL/2-72 AC A0A0K9R7I7.1
#=GS D7LGQ5_ARALL/2-72 AC D7LGQ5.1
#=GS A0A8C6Y932_NAJNA/1-96 AC A0A8C6Y932.1
#=GS A0A1D2VEJ3_9ASCO/2-66 AC A0A1D2VEJ3.1
#=GS A0A3P7JAK1_STRVU/24-85 AC A0A3P7JAK1.1
#=GS A0A8K0DTI9_9ROSA/2-73 AC A0A8K0DTI9.1
#=GS A0A7K5YKG9_9AVES/1-96 AC A0A7K5YKG9.1
#=GS D6WSS5_TRICA/10-96 AC D6WSS5.1
#=GS X0CL83_FUSOX/64-143 AC X0CL83.1
#=GS A0A165SUD6_9AGAM/4-77 AC A0A165SUD6.1
#=GS G4ZU07_PHYSP/1-70 AC G4ZU07.1
#=GS A0A2G9UNQ4_TELCI/26-100 AC A0A2G9UNQ4.1
#=GS A0A7L1YCH5_9PASS/1-59 AC A0A7L1YCH5.1
#=GS A0A6P6X1H5_COFAR/1-72 AC A0A6P6X1H5.1
#=GS A0A8H4LID3_9HYPO/3-72 AC A0A8H4LID3.1
#=GS A0A384CCP1_URSMA/1-96 AC A0A384CCP1.1
#=GS A0A061DQI1_THECC/2-73 AC A0A061DQI1.1
#=GS A0A8H6C5R9_CANAX/1-75 AC A0A8H6C5R9.1
#=GS A0A8C0EJI6_BUBBB/9-89 AC A0A8C0EJI6.1
#=GS A0A200PWP1_9MAGN/1-72 AC A0A200PWP1.1
#=GS A0A1B9GPV7_9TREE/7-75 AC A0A1B9GPV7.1
#=GS A0A8H4UQ02_9HYPO/2-72 AC A0A8H4UQ02.1
#=GS A0A6A3YIX6_9STRA/1-70 AC A0A6A3YIX6.1
#=GS A0A851FAP9_PITSO/1-96 AC A0A851FAP9.1
#=GS A0A6A5PAZ6_LUPAL/2-71 AC A0A6A5PAZ6.1
#=GS A0A812CCI1_SEPPH/173-266 AC A0A812CCI1.1
#=GS A0A8B9IBW0_9AVES/1-96 AC A0A8B9IBW0.1
#=GS A0A6A5CGR2_NAEFO/1-78 AC A0A6A5CGR2.1
#=GS A0A210Q9H1_MIZYE/2-94 AC A0A210Q9H1.1
#=GS A0A7J8FA21_MOLMO/1-96 AC A0A7J8FA21.1
#=GS A0A7K6YJI4_ALCTO/1-96 AC A0A7K6YJI4.1
#=GS T0R435_SAPDV/1-74 AC T0R435.1
#=GS A0A835GPK8_SPOEX/107-189 AC A0A835GPK8.1
#=GS A0A7L1DQA9_OENON/1-87 AC A0A7L1DQA9.1
#=GS A0A6I9Z1L0_9SAUR/50-145 AC A0A6I9Z1L0.1
#=GS A0A3P7P683_CYLGO/22-80 AC A0A3P7P683.1
#=GS A0A2G9T4V1_TELCI/21-79 AC A0A2G9T4V1.1
#=GS A0A6P4JTE5_DROKI/11-89 AC A0A6P4JTE5.1
#=GS A0A5B1QTG2_9AGAM/2-76 AC A0A5B1QTG2.1
#=GS A0A1W2TQT5_ROSNE/1-76 AC A0A1W2TQT5.1
#=GS A0A1S4CY61_TOBAC/1-73 AC A0A1S4CY61.1
#=GS F1SV23_PIG/1-96 AC F1SV23.1
#=GS A0A7J7E3G9_DICBM/59-154 AC A0A7J7E3G9.1
#=GS A0A3N0XZH2_ANAGA/1-96 AC A0A3N0XZH2.1
#=GS A0A8C7KYJ0_ONCKI/1-96 AC A0A8C7KYJ0.1
#=GS A0A397Z5M8_BRACM/2-72 AC A0A397Z5M8.1
#=GS A0A1Q3BGE5_CEPFO/2-75 AC A0A1Q3BGE5.1
#=GS V4BC71_LOTGI/30-103 AC V4BC71.1
#=GS A0A830H7A3_9CHLO/2-74 AC A0A830H7A3.1
#=GS A0A2K5CVE2_AOTNA/1-22 AC A0A2K5CVE2.1
#=GS A0A5D3E0B9_CUCME/3-62 AC A0A5D3E0B9.1
#=GS A0A1S3E3K4_CICAR/2-73 AC A0A1S3E3K4.1
#=GS A0A7N1A0D0_KALFE/1-74 AC A0A7N1A0D0.1
#=GS A0A0D2C102_9EURO/2-75 AC A0A0D2C102.1
#=GS A0A1U8LI85_GOSHI/2-72 AC A0A1U8LI85.1
#=GS A0A7L2RTL6_9PASS/1-72 AC A0A7L2RTL6.1
#=GS A0A7K7MKG6_9PASS/1-96 AC A0A7K7MKG6.1
#=GS B6Q673_TALMQ/3-73 AC B6Q673.1
#=GS A0A6J8DZB1_MYTCO/58-141 AC A0A6J8DZB1.1
#=GS A0A261B6T3_9PELO/23-100 AC A0A261B6T3.1
#=GS A0A8H6ZRE5_PLEOS/5-77 AC A0A8H6ZRE5.1
#=GS A0A8R1E7E4_CAEJA/23-100 AC A0A8R1E7E4.1
#=GS A0A0E0IFQ2_ORYNI/2-80 AC A0A0E0IFQ2.1
#=GS A0A852AGK7_CALOR/1-96 AC A0A852AGK7.1
#=GS A0A7K8P3A1_COCCO/1-96 AC A0A7K8P3A1.1
#=GS A0A6P5B4C1_BOSIN/1-96 AC A0A6P5B4C1.1
#=GS F4WG49_ACREC/75-156 AC F4WG49.1
#=GS A0A834NNG7_VESGE/7-100 AC A0A834NNG7.1
#=GS A0A7L2NB92_9PASS/71-97 AC A0A7L2NB92.1
#=GS F7AT92_HORSE/6-101 AC F7AT92.2
#=GS A0A6G1QXC5_9TELE/1-96 AC A0A6G1QXC5.1
#=GS A0A1S3F8A4_DIPOR/1-96 AC A0A1S3F8A4.1
#=GS A0A2Z7BCY2_9LAMI/1-72 AC A0A2Z7BCY2.1
#=GS A0A852PGP8_9PASS/1-96 AC A0A852PGP8.1
#=GS A0A0K0JPN4_BRUMA/25-103 AC A0A0K0JPN4.1
#=GS G3TGB9_LOXAF/1-96 AC G3TGB9.1
#=GS A0A5J5A8Q8_9ASTE/2-72 AC A0A5J5A8Q8.1
#=GS A0A7L3D1M9_PLUSO/1-72 AC A0A7L3D1M9.1
#=GS A0A8D2QGU8_ZONAL/9-85 AC A0A8D2QGU8.1
#=GS A0A5F8G3Y9_MONDO/66-161 AC A0A5F8G3Y9.1
#=GS A0A8D2GQ82_UROPR/1-98 AC A0A8D2GQ82.1
#=GS A0A3P8TBX7_AMPPE/1-96 AC A0A3P8TBX7.1
#=GS A0A2B7Y890_9EURO/2-74 AC A0A2B7Y890.1
#=GS A0A4Z2BJV8_9TELE/140-235 AC A0A4Z2BJV8.1
#=GS A0A8B8PCH5_9MYRT/2-72 AC A0A8B8PCH5.1
#=GS A0A7L1NFS0_RHICY/1-96 AC A0A7L1NFS0.1
#=GS A0A7K7PTE3_ACRAR/1-72 AC A0A7K7PTE3.1
#=GS A0A7J7ZWU9_MYOMY/190-285 AC A0A7J7ZWU9.1
#=GS A0A074Z8U8_9TREM/99-175 AC A0A074Z8U8.1
#=GS A0A8C2XSU0_CYCLU/52-147 AC A0A8C2XSU0.1
#=GS A0A8K0KJD0_LADFU/1-61 AC A0A8K0KJD0.1
#=GS A0A821VWY2_9NEOP/9-91 AC A0A821VWY2.1
#=GS A0A437CVW4_ORYJA/1-96 AC A0A437CVW4.1
#=GS A0A2K1JUK7_PHYPA/1-74 AC A0A2K1JUK7.1
#=GS A0A7L0U1K1_CHOAC/1-96 AC A0A7L0U1K1.1
#=GS A0A663EL67_AQUCH/1-96 AC A0A663EL67.1
#=GS B3MUC9_DROAN/11-88 AC B3MUC9.1
#=GS A0A8U0MG39_MUSPF/1-96 AC A0A8U0MG39.1
#=GS A0A094ETL3_9PEZI/2-75 AC A0A094ETL3.1
#=GS A0A6P7JME3_9TELE/1-96 AC A0A6P7JME3.1
#=GS A0A7N5K8Y9_AILME/1-96 AC A0A7N5K8Y9.1
#=GS A0A212F879_DANPL/11-89 AC A0A212F879.1
#=GS V4KND9_EUTSA/2-73 AC V4KND9.1
#=GS A0A852HVD1_9PASS/1-96 AC A0A852HVD1.1
#=GS L5JTZ5_PTEAL/190-285 AC L5JTZ5.1
#=GS A0A804LB99_MUSAM/2-72 AC A0A804LB99.1
#=GS A0A7K9JZ08_9PASE/1-96 AC A0A7K9JZ08.1
#=GS A0A1V9X3T6_9ACAR/10-95 AC A0A1V9X3T6.1
#=GS A0A212CH38_CEREH/86-170 AC A0A212CH38.1
#=GS A0A6F9CQI5_9TELE/1-96 AC A0A6F9CQI5.1
#=GS B5RSL7_YARLI/9-76 AC B5RSL7.1
#=GS H9H3F4_MACMU/1-96 AC H9H3F4.1
#=GS A0A7L4JFT3_9PASS/1-96 AC A0A7L4JFT3.1
#=GS A0A8J2S822_9CRUS/9-98 AC A0A8J2S822.1
#=GS A0A2R6P5T0_ACTCC/1-73 AC A0A2R6P5T0.1
#=GS A0A6G1GF64_9PEZI/1-83 AC A0A6G1GF64.1
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A0A851JKG9_9PASS/1-96 .........................................................MPFWGLQKQL.GIDVDSWLLRQSMPQPHGQ.AA...ACHAFEREWV..E.C...G...H...G.L...G.....Q..T.....R..A...R....RE...CQLEY.EDFMECM....QR....TK.............M.......AQR..L...RTI..L....E....Q.R...D...KM......I......KQG.K...YTPP-d................................
A0A7K8G7L7_ORTSP/1-59 .........................................................MPFWGLQKQL.GIDVDSFLLRQSMPQPYGQ.AG...ACHAFEREWV..E.C...G...H...G.X...X.....-..-.....-..-...-....--...-----.-------....--....--.............-.......---..-...---..-....-....-.-...-...--......-......---.-...-----xxgtrgargtg......................
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#=GC seq_cons ........................................................................................su...+CasFEp-Wl..-.C...u...c...u.h...G.....p..s.....R..u...c....+-...Cplth.EDahECl....p+....pK.............p.......hpR..h...ptI..h....c....p.c...p...+.......h......t............t................................
//
