#=GF ID Ntox33
#=GF AC PF15533.10
#=GF DE Bacterial toxin 33
#=GF PI Toxin_54; Toxin_33;
#=GF AU Zhang D;0000-0001-8535-7620
#=GF AU de Souza RF;0000-0002-5284-4630
#=GF AU Anantharaman V;0000-0001-8395-0009
#=GF AU Iyer LM;0000-0002-4844-2022
#=GF AU Aravind L;0000-0003-0771-253X
#=GF AU Finn RD;0000-0001-8626-2148
#=GF SE [1]
#=GF GA 28.40 28.40;
#=GF TC 28.70 29.90;
#=GF NC 27.90 28.30;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 22731697
#=GF RT Polymorphic toxin systems: comprehensive characterization of
#=GF RT trafficking modes, processing, mechanisms of action, immunity
#=GF RT and ecology using comparative genomics.
#=GF RA Zhang D, de Souza RF, Anantharaman V, Iyer LM, Aravind L;
#=GF RL Biol Direct. 2012;7:18.
#=GF DR INTERPRO; IPR029110;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC A predicted RNase toxin found in bacterial polymorphic toxin
#=GF CC systems. The toxin possesses an alpha+beta fold and [DN]xHxxK
#=GF CC and DxxxD motifs. It is usually exported by the Type 2 secretory
#=GF CC system [1].
#=GF SQ 24
#=GS A0A2T1G658_9CYAN/14-77 AC A0A2T1G658.1
#=GS A0A7V7QLB1_9FIRM/146-219 AC A0A7V7QLB1.1
#=GS A0A0P4UZD0_9CYAN/6-57 AC A0A0P4UZD0.1
#=GS D8G3P8_9CYAN/11-74 AC D8G3P8.1
#=GS A0A1C4G7W5_9BACT/42-103 AC A0A1C4G7W5.1
#=GS B7K0I9_RIPO1/6-44 AC B7K0I9.1
#=GS A0A1S2VR60_9BACT/961-1025 AC A0A1S2VR60.1
#=GS K6SWH1_9CLOT/5-72 AC K6SWH1.1
#=GS A0A4P8XF46_9BACL/1-43 AC A0A4P8XF46.1
#=GS A0A0D6ZGR0_9BACI/1325-1394 AC A0A0D6ZGR0.1
#=GS A0A7W7Q226_9PSEU/99-160 AC A0A7W7Q226.1
#=GS L8JSJ1_9BACT/395-456 AC L8JSJ1.1
#=GS A0A1M6HYK2_9FLAO/46-110 AC A0A1M6HYK2.1
#=GS H8KRI4_SOLCM/804-868 AC H8KRI4.1
#=GS Q81BC9_BACCR/167-236 AC Q81BC9.1
#=GS D6ZEE4_SEGRD/407-470 AC D6ZEE4.1
#=GS A0A1C0VUK9_9CYAN/11-74 AC A0A1C0VUK9.1
#=GS A0A3A9FJZ9_9BACT/52-124 AC A0A3A9FJZ9.1
#=GS R3WA01_9ENTE/2983-3052 AC R3WA01.1
#=GS A0A2P8DCY3_9BACT/1950-2011 AC A0A2P8DCY3.1
#=GS A0A4Q2LJM7_9BACL/214-281 AC A0A4Q2LJM7.1
#=GS A0A6B2FTW7_9ENTR/3325-3394 AC A0A6B2FTW7.1
#=GS A0A401G0Y5_9DELT/2888-2956 AC A0A401G0Y5.1
#=GS A0A0X3AP93_9FLAO/2083-2148 AC A0A0X3AP93.1
A0A2T1G658_9CYAN/14-77 .........nw--RQDKLLTKQEIERLKTG.E.I.DIHEIK....NE.ENASKK-DLYKDRD.GNIYVKPKG.G...MSP.GEPTDININ........
A0A7V7QLB1_9FIRM/146-219 .....sktenl------DLDKVNDKYLKKK.G.V.DAHQLKkdiyGK.KAKVAEYDIYVDKNtGELYTQRKP.QyniKGEsPIATGEYI-k.......
A0A0P4UZD0_9CYAN/6-57 .........dw--QQDQLLSSGEIAKLKQS.E.I.DVHELK....G-.GRGASKLDLYKDKD.GNIYIFVK-.-...---.---------ve......
D8G3P8_9CYAN/11-74 .........nw--RQDKLLTWDDIDRLQRG.G.E.NIHKIK....GK.RNTANK-DLYKDTE.GNIYIKPKG.G...IGA.GEPTGLNIN........
A0A1C4G7W5_9BACT/42-103 ...........NPSQDKKLTPGEIEKLKEK.GvW.DHHDKD....--.--FGSRFDLYKDRK.GNVYEKPKG.G...LGP.GDPIGINLN........
B7K0I9_RIPO1/6-44 .........nw--RQDKLLTPYEIAKLKQS.G.L.DIHDLK....GG.KNA-SKKD------.---------.-...---.---------gst.....
A0A1S2VR60_9BACT/961-1025 ...........NPTQDKMLTPGEIKRLEDG.G.V.DVHELK....GN.KKTGQK-DLYKKPN.GDILIKPKGgG...KME.GEETGYNIK........
K6SWH1_9CLOT/5-72 ........gsn----PTNIKMVNDKYLKKQ.G.I.DAHSLKq.dfVG.KNNIAHYDIYVDKEtGMLWIYRKG.G...KGE.PIPTYEYIK........
A0A4P8XF46_9BACL/1-43 ........mkk-------------------.-.-.---ETY....GK.NAEISKYDLYVDKStGQIYAMRKG.G...KGE.PTPTGTF--........
A0A0D6ZGR0_9BACI/1325-1394 ....vknktkl------NIEKVKDSYLKRK.G.I.NAHDLKkefiGR.KAKISHYDIYKDKTtGQLYIYKKG.G...KGT.GIPTGTYI-........
A0A7W7Q226_9PSEU/99-160 .....tpqpdg------VPKKRDDKWLKRN.G.V.DPHEVK....GDlPGPMSHFDLYVDRS.GNIWAVRKG.A...---.---------dprsgeyv
L8JSJ1_9BACT/395-456 ....niklikp-------------NMLKKA.G.I.DAHALKk.efLG.SKGISKFDLYRHTEtGEILILKKG.G...VGE.AIFTGIFL-........
A0A1M6HYK2_9FLAO/46-110 .........gs--NQDKRLSPGEIKKLKDA.G.W.DHSEKG....VN.GKGGGQKDLWKDKN.GNVYEKPKN.G...KGP.GEPIGVNLN........
H8KRI4_SOLCM/804-868 ...........NPAQDKPLSDGEIELLEKN.G.F.NHRDKS....MN.GKRGGRLDLWKDGE.GNVYEKPKG.N...KGP.GEPIGYNLK........
Q81BC9_BACCR/167-236 ...........MKQVPKSINKVDDKFLKRK.G.I.DAHELKrdylGR.SVSISKYDIYVDKKtGRLWIYLKG.G...KGT.PIPTDSFIK........
D6ZEE4_SEGRD/407-470 ...........NPAQDKLLTKGDIQKLKDA.G.Y.DIHDLK....GY.GNAANR-DLYKDRG.GNIYVKPKG.G...SGE.GESLNININ........
A0A1C0VUK9_9CYAN/11-74 .........nw--RQDKLLTCDDIDRLQRG.G.E.NIHKIK....GK.RNTANK-DLYKDTE.GNIYIKPKG.G...IGA.GESTGLNIN........
A0A3A9FJZ9_9BACT/52-124 nkdgdnskanc--------DKVNESYLEDK.G.I.DAHRLKrdilGK.KTQIAHYDIYVDKNtGELIIFLKG.G...KGV.GIPTGEFIK........
R3WA01_9ENTE/2983-3052 ..........e-PEQPSNKEKVNDNYLKNK.G.F.DGHKVKeetrGT.TKDGSKYDIYVDKDtGQLWVFRKG.G...KGE.GIPTGEYIK........
A0A2P8DCY3_9BACT/1950-2011 ..........n-VKQDKALSKGEIEKLKRN.G.W.DHTDK-....--.GDHGGQTDLYKDKQ.GNVYQKPKG.G...IGA.GEPIGVNLN........
A0A4Q2LJM7_9BACL/214-281 ....kapirvn-------LQKIDDKYLERK.G.I.NAHEIKd..dLL.GGSISKGDLYVDKNtGQVFVMRKG.G...TGE.PIPTGYILK........
A0A6B2FTW7_9ENTR/3325-3394 ......qkeek----PSNIKMADDKYLKRN.G.I.DAHKLKeeflGD.GKNSN-YDIYINKDsGELWIFRKG.G...KGD.GIATGEFIK........
A0A401G0Y5_9DELT/2888-2956 kedryldkdel---------KALKKKIKKD.G.YkNVEELK...tPH.GKNAGKYDLYVKPD.GNIVVKPKG.G...AGI.GEPTGYNI-y.......
A0A0X3AP93_9FLAO/2083-2148 .........nw--RQDKLLSKGEINRLEKAiG.W.NHGDKG....QN.NRGGGKKDLYKDKD.GNIYEKPKG.G...KGP.GEWTGINIK........
#=GC seq_cons .........p.....sp.lsps-.chLKcs.G.h.DhH-lK....sp.tpssu+hDLYhD+s.Gplalh.KG.G...tG..G.sTGh.lp........
//
