#=GF ID Ntox8
#=GF AC PF15545.10
#=GF DE Bacterial toxin 8
#=GF PI Toxin_67; Toxin_8;
#=GF AU Zhang D;0000-0001-8535-7620
#=GF AU de Souza RF;0000-0002-5284-4630
#=GF AU Anantharaman V;0000-0001-8395-0009
#=GF AU Iyer LM;0000-0002-4844-2022
#=GF AU Aravind L;0000-0003-0771-253X
#=GF AU Finn RD;0000-0001-8626-2148
#=GF SE [1]
#=GF GA 25.00 25.00;
#=GF TC 26.90 28.40;
#=GF NC 24.70 20.00;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 22731697
#=GF RT Polymorphic toxin systems: comprehensive characterization of
#=GF RT trafficking modes, processing, mechanisms of action, immunity
#=GF RT and ecology using comparative genomics.
#=GF RA Zhang D, de Souza RF, Anantharaman V, Iyer LM, Aravind L;
#=GF RL Biol Direct. 2012;7:18.
#=GF DR INTERPRO; IPR029097;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC A predicted RNase toxin found in bacterial polymorphic toxin
#=GF CC systems. The toxin possesses an alpha+beta fold and HxR and
#=GF CC HxxxH motifs and is usually exported by the type 2 and type 6
#=GF CC secretion system [1].
#=GF SQ 22
#=GS A0A1M7KKA1_9BACI/2662-2731 AC A0A1M7KKA1.1
#=GS A0A0U3N9L7_9HYPH/299-368 AC A0A0U3N9L7.1
#=GS A0A226DRF6_FOLCA/1821-1890 AC A0A226DRF6.1
#=GS A0A017RRA3_9CLOT/406-475 AC A0A017RRA3.1
#=GS W1N0R1_9GAMM/139-206 AC W1N0R1.1
#=GS A0A443J238_9BACI/335-404 AC A0A443J238.1
#=GS A0A1A8TSB5_9GAMM/5562-5631 AC A0A1A8TSB5.1
#=GS A0A562IMB2_9ACTN/2535-2598 AC A0A562IMB2.1
#=GS D3BNJ9_POLPP/1-33 AC D3BNJ9.1
#=GS A0A1K1STK0_9BACT/1329-1400 AC A0A1K1STK0.1
#=GS A0A317EGZ7_9PROT/56-125 AC A0A317EGZ7.1
#=GS V8G868_9BURK/48-116 AC V8G868.1
#=GS A0A1E2VD88_9GAMM/1495-1564 AC A0A1E2VD88.1
#=GS A0A3A1R0J6_9BACI/2583-2652 AC A0A3A1R0J6.1
#=GS A0A323UUW1_9RHOO/275-344 AC A0A323UUW1.1
#=GS A0A2N4X6S6_9BACT/163-232 AC A0A2N4X6S6.1
#=GS A0A2S8AFN8_9FLAO/3-68 AC A0A2S8AFN8.1
#=GS A0A160F769_9BACI/366-435 AC A0A160F769.1
#=GS M9M4T2_PAEPP/1-60 AC M9M4T2.1
#=GS A0A495XLK0_9PSEU/1663-1726 AC A0A495XLK0.1
#=GS A0Q1W6_CLONN/21-90 AC A0Q1W6.1
#=GS A0A401FR19_9DELT/1814-1891 AC A0A401FR19.1
A0A1M7KKA1_9BACI/2662-2731 .......ia--NDDKVSTALRGEIKRDINEIKLGK..RKNIRVP......Q..GYNLAHRRGYEARKGYGYEYSDLQTIRSHR.TQHKHD..
A0A0U3N9L7_9HYPH/299-368 ........l-ANDDKLGSADRGWLKQELNSIDRGK..RSTMRNP......P..GKDLAHERGREAAKGYDYRHSNLQDRDLHR.LQHKYD..
A0A226DRF6_FOLCA/1821-1890 .......im--NDPKQGSHIRGWIRQEVNQIERGQ..RNYIRNP......P..GHDLAHWRGYESAKGYDYSHSNLQVRDLHK.LQHKYD..
A0A017RRA3_9CLOT/406-475 ........i-AKDDKVSSALRGEIKRDINQINRGK..RTTIRVP......N..GYQMAHKRGYEARKGFGYSHSVLNDTNLHK.LQHKYD..
W1N0R1_9GAMM/139-206 ..qdprqpa---------HVRGWIQQEQNAITQGN..RTNIRNP......P..GYQLAHRRGYEAQKGFGYEYSEPQHTDLHR.LQHRYD..
A0A443J238_9BACI/335-404 .........LINDPKQPKHVRGWIRNEKRHIKNGK..RKNIRVP......I..GYELAHKRSYEARKGASYKHSSLQVIRNHR.LQHFY-d.
A0A1A8TSB5_9GAMM/5562-5631 .......lg--DDPKLGEADRGWIKQEKNSIARGN..RKTIRNP......P..GKDLAHERGREAAKGYGYEHSNLQDRKLHR.LQHKYD..
A0A562IMB2_9ACTN/2535-2598 .........LINNDKVSRTIRGELA---NLAKQKK..R--LRV-......D..GMQMAHRRTHEAAKGCGYQCSVLQTRGNHM.RQHRID..
D3BNJ9_POLPP/1-33 .........--------------------------..-------......-..---MAHHRGFEAAKGFSYKFSSLQVIDLHR.LQHRYD..
A0A1K1STK0_9BACT/1329-1400 ....vgddp-----KQGSATRGWIKQERNAMQRDRkaRPGIRNP......P..GTELAHDRGKEAAKGYNYDDSKLKTKELHD.LQHRT-e.
A0A317EGZ7_9PROT/56-125 .........LVNDDTLGAADRGWIRQELNSIDRGQ..RSTIRNP......P..GKDLAHERGREAAKGYDYSHSNLQDRDLHR.LQHKYD..
V8G868_9BURK/48-116 .........LLNDVKAPKHIRGWIQQELNRIK-GT..KKRIRVP......P..GYDLAHWRGYENAKGFDYTYTDLNFKRNHK.IQHRFD..
A0A1E2VD88_9GAMM/1495-1564 ......igq---DPKQPNHVRGWIQQEQNSISSGK..RRSIRNP......P..GYQMAHRRGYESQKGFGYEYSEPQHIDLHR.LQHRYD..
A0A3A1R0J6_9BACI/2583-2652 .......ia--NDDKVSRALRGDIIRDINEIKRGK..RKSIRVP......Q..GYNLAHRRGYEARKGYGYEHSDLQTIRSHK.TQHKHD..
A0A323UUW1_9RHOO/275-344 ....vmndp-----NTPKSMRGWLQNQTRRVATGK..QANIKTP......P..GYELAHRPRFESELGYDYSHADPMLAADHRgIQHR--y.
A0A2N4X6S6_9BACT/163-232 .......ia--NDPKASSADRGWIKQDMNEIAKGK..RENIRNP......P..GKDLAHERGREAAKGYSYEHSNLQDRDLHR.QQHKHD..
A0A2S8AFN8_9FLAO/3-68 lnwgkqigl-------------RLNRKLKLIKQSK..RKSIRNP......P..GKELAHERGREAAKGYSYEHSKLQNKKDHR.AQHKYD..
A0A160F769_9BACI/366-435 .......ia--NDNKVSSALRGEIKRDMNEIAAGK..RKNIRVP......Q..GYELAHRRGYEARNGYGYEHSDLQMIKNHR.TQHKHD..
M9M4T2_PAEPP/1-60 ........m-----------HGEIKRDMNEIKQGK..RPTIRVP......Q..GYQLAHRRGFEARKGYGYRYSDLQMIKNHR.TQHKYD..
A0A495XLK0_9PSEU/1663-1726 ........l-ANDPKVAKHLRGFIK---NQVRQGR..Q---KLP......P..GYQLAHYRTHEAARGCSYRCSHLNTRELHR.LQHKHD..
A0Q1W6_CLONN/21-90 .........LVKDLKLSRSLRGELKRDINLIKKGR..RRTIRVP......K..GYELAHRRGFEARKGYGYAYSDLQVIRNHR.IQHRID..
A0A401FR19_9DELT/1814-1891 ........l-ANDPKVSSADRGWIKNEIRHIETGS..RKTIRLPgnsrnsKqgGKVLAHPRGKRAKDGWGYEYSNLQDTDLHK.LEHK--ye
#=GC seq_cons ...........pDsKhupthRGhI+p-hNpIppG+..RpsIRsP......s..GhpLAHcRGaEAtKGauYcaSsLQstc.HR.lQH+aD..
//
