#=GF ID Nuc_N
#=GF AC PF14448.10
#=GF DE Nuclease N terminal
#=GF PI NUC_N;
#=GF AU Zhang D;0000-0001-8535-7620
#=GF AU Iyer LM;0000-0002-4844-2022
#=GF AU Aravind L;0000-0003-0771-253X
#=GF AU Eberhardt R;0000-0001-6152-1369
#=GF SE Zhang D, Iyer LM, Aravind L
#=GF GA 25.00 25.00;
#=GF TC 28.50 41.10;
#=GF NC 24.20 17.60;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 21306995
#=GF RT A novel immunity system for bacterial nucleic acid degrading
#=GF RT toxins and its recruitment in various eukaryotic and DNA viral
#=GF RT systems.
#=GF RA Zhang D, Iyer LM, Aravind L;
#=GF RL Nucleic Acids Res. 2011;39:4532-4552.
#=GF DR INTERPRO; IPR027803;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This is a conserved short region that is found in many bacterial
#=GF CC polymorphic toxin proteins [1]. It is often located before
#=GF CC C-terminal nuclease domains [1].
#=GF SQ 6
#=GS Q813C4_BACCR/1-45 AC Q813C4.1
#=GS Q813C3_BACCR/20-77 AC Q813C3.1
#=GS Q65FQ0_BACLD/338-394 AC Q65FQ0.1
#=GS A0A2A8SIG7_9BACI/361-416 AC A0A2A8SIG7.1
#=GS A0A2A8SHW7_9BACI/1-40 AC A0A2A8SHW7.1
#=GS A0A073JUK8_9BACI/364-420 AC A0A073JUK8.1
Q813C4_BACCR/1-45 ........m--------------PDGSV.VRSGTNYSGKFQEAHDASKASIQSRVSNLESGG...VKGTGN
Q813C3_BACCR/20-77 .........ADSVSPIFKGVEILPDGSV.VRSGTNYSGKFQEAHDASKASIQSRISNLESGG...VKGTGE
Q65FQ0_BACLD/338-394 .........ADALSDIARGAEAGAGGTL.VRKGSNYSAHVNDAHKASKAKMQDSIQRVEKE-...IEAGKS
A0A2A8SIG7_9BACI/361-416 kdfvlgksl------------APVDGVMgLNRGTNWEAAVKASHEESKGIIQSRISKLEESA...VKGTGD
A0A2A8SHW7_9BACI/1-40 .......mg-------------------.LRRGTNWEAAAKASHDESKGIIHNKISKLEES-...VKGTGE
A0A073JUK8_9BACI/364-420 .........FVSVKSL-----VPADGAMqLRRGTDLESRVKASHAESKADIQSRISKLEQEGrlnTKGTGD
#=GC seq_cons .....................h.sDGsh.lR+GTNapu+spsuH-tSKApIQSRIS+LEpuu...VKGTG-
//
