#=GF ID   ORC1_wHTH
#=GF AC   PF21312.1
#=GF DE   Origin recognition complex subunit 1 C-terminal winged HTH domain
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   ECOD:EF24674
#=GF GA   24.30 24.30;
#=GF TC   24.30 24.30;
#=GF NC   24.20 24.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP   Domain
#=GF CL   CL0123
#=GF RC   Paper describing PDB structure 5v8f
#=GF RN   [1]
#=GF RM   28191893
#=GF RT   Structural basis of Mcm2-7 replicative helicase loading by
#=GF RT   ORC-Cdc6 and Cdt1.
#=GF RA   Yuan Z, Riera A, Bai L, Sun J, Nandi S, Spanos C, Chen ZA,
#=GF RA   Barbon M, Rappsilber J, Stillman B, Speck C, Li H;
#=GF RL   Nat Struct Mol Biol. 2017;24:316-324.
#=GF RC   Paper describing PDB structure 5zr1
#=GF RN   [2]
#=GF RM   29973722
#=GF RT   Structure of the origin recognition complex bound to DNA
#=GF RT   replication origin.
#=GF RA   Li N, Lam WH, Zhai Y, Cheng J, Cheng E, Zhao Y, Gao N, Tye BK;
#=GF RL   Nature. 2018;559:217-222.
#=GF RC   Paper describing PDB structure 6wgc
#=GF RN   [3]
#=GF RM   32669428
#=GF RT   Structural mechanism of helicase loading onto replication origin
#=GF RT   DNA by ORC-Cdc6.
#=GF RA   Yuan Z, Schneider S, Dodd T, Riera A, Bai L, Yan C, Magdalou I,
#=GF RA   Ivanov I, Stillman B, Li H, Speck C;
#=GF RL   Proc Natl Acad Sci U S A. 2020;117:17747-17756.
#=GF RC   Paper describing PDB structure 7mca
#=GF RN   [4]
#=GF RM   34162887
#=GF RT   The structure of ORC-Cdc6 on an origin DNA reveals the mechanism
#=GF RT   of ORC activation by the replication initiator Cdc6.
#=GF RA   Feng X, Noguchi Y, Barbon M, Stillman B, Speck C, Li H;
#=GF RL   Nat Commun. 2021;12:3883.
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This entry represents the C-terminal winged helix-turn-helix
#=GF CC   domain found in the Origin recognition complex subunit 1 protein
#=GF CC   [1].
#=GF SQ   380
#=GS Q2U2R6_ASPOR/353-440        AC Q2U2R6.1
#=GS A0A423VL81_9PEZI/616-736    AC A0A423VL81.1
#=GS A0A0D1ZG34_9EURO/624-733    AC A0A0D1ZG34.1
#=GS A0A6A6YZ32_9PEZI/652-771    AC A0A6A6YZ32.1
#=GS A0A5Q4BGN2_9PEZI/611-729    AC A0A5Q4BGN2.1
#=GS A0A136J4Y0_9PEZI/616-741    AC A0A136J4Y0.1
#=GS N4UP27_FUSC1/575-690        AC N4UP27.1
#=GS A0A8J8W538_9EURO/658-782    AC A0A8J8W538.1
#=GS A0A1S8BLD9_9PEZI/686-744    AC A0A1S8BLD9.1
#=GS A0A8E2EYS7_9PEZI/640-772    AC A0A8E2EYS7.1
#=GS A0A094G1F3_9PEZI/726-847    AC A0A094G1F3.1
#=GS A3LX69_PICST/660-785        AC A3LX69.2
#=GS C0NJ64_AJECG/693-791        AC C0NJ64.1
#=GS A0A319EQP2_ASPSB/661-743    AC A0A319EQP2.1
#=GS A0A4Q4VKT2_9PEZI/613-733    AC A0A4Q4VKT2.1
#=GS A0A1L9UQD3_ASPBC/665-748    AC A0A1L9UQD3.1
#=GS A0A093ZDJ8_9PEZI/650-770    AC A0A093ZDJ8.1
#=GS A0A218Z700_9HELO/633-749    AC A0A218Z700.1
#=GS A0A2I1C9H9_ASPN1/664-752    AC A0A2I1C9H9.1
#=GS A0A0G4MAL0_9PEZI/605-725    AC A0A0G4MAL0.1
#=GS A7TNP8_VANPO/797-911        AC A7TNP8.1
#=GS A0A139HGC5_9PEZI/612-746    AC A0A139HGC5.1
#=GS I2H569_TETBL/884-1005       AC I2H569.1
#=GS A0A8H3G011_9LECA/611-738    AC A0A8H3G011.1
#=GS J7RM84_KAZNA/750-863        AC J7RM84.1
#=GS A0A875RW59_EENNA/658-775    AC A0A875RW59.1
#=GS C5GML0_AJEDR/682-779        AC C5GML0.1
#=GS A0A1E5RH42_9ASCO/869-996    AC A0A1E5RH42.1
#=GS A0A1D2VP20_9ASCO/776-889    AC A0A1D2VP20.1
#=GS A0A3D8RRK9_9EURO/661-748    AC A0A3D8RRK9.1
#=GS J8Q1I6_SACAR/809-922        AC J8Q1I6.1
#=GS A0A383UID2_BLUHO/589-709    AC A0A383UID2.1
#=GS T0KH56_COLGC/587-706        AC T0KH56.1
#=GS A0A072P1T4_9EURO/627-739    AC A0A072P1T4.1
#=GS A0A175VWT2_9PEZI/607-735    AC A0A175VWT2.1
#=GS A0A084G3B6_PSEDA/426-546    AC A0A084G3B6.1
#=GS G2XFC8_VERDV/536-656        AC G2XFC8.1
#=GS X0CCY9_FUSOX/593-708        AC X0CCY9.1
#=GS A0A2J6Q9K1_9HELO/620-740    AC A0A2J6Q9K1.1
#=GS C6H984_AJECH/685-781        AC C6H984.1
#=GS A0A1E3NS62_9ASCO/637-756    AC A0A1E3NS62.1
#=GS A0A4S3JLA8_9EURO/669-793    AC A0A4S3JLA8.1
#=GS A0A094GQ91_9PEZI/651-772    AC A0A094GQ91.1
#=GS A0A074Y0Q5_AURSE/608-654    AC A0A074Y0Q5.1
#=GS A0A0D2X842_FUSO4/593-708    AC A0A0D2X842.1
#=GS A0A8H6J5U2_9PEZI/594-713    AC A0A8H6J5U2.1
#=GS A6R1C9_AJECN/674-772        AC A6R1C9.1
#=GS W9X3D3_9EURO/632-747        AC W9X3D3.1
#=GS A0A1Y2DBN6_9PEZI/602-722    AC A0A1Y2DBN6.1
#=GS C1G4S1_PARBD/696-789        AC C1G4S1.1
#=GS A0A0D2DPC5_9EURO/642-757    AC A0A0D2DPC5.1
#=GS A0A8H8UHE4_9HELO/625-743    AC A0A8H8UHE4.1
#=GS A0A1A0HDG1_9ASCO/784-905    AC A0A1A0HDG1.1
#=GS G0VKZ2_NAUCC/879-992        AC G0VKZ2.1
#=GS Q756Y1_ASHGO/874-988        AC Q756Y1.2
#=GS A0A1L0BAC3_9ASCO/652-777    AC A0A1L0BAC3.1
#=GS A0A017SES5_ASPRC/656-782    AC A0A017SES5.1
#=GS A0A094DN79_9PEZI/650-770    AC A0A094DN79.1
#=GS A0A2A9PUY0_9HYPO/595-710    AC A0A2A9PUY0.1
#=GS H1VVQ3_COLHI/115-233        AC H1VVQ3.1
#=GS A0A8H8WN75_COLGL/599-718    AC A0A8H8WN75.1
#=GS A0A1S7HZC5_9SACH/875-988    AC A0A1S7HZC5.1
#=GS A0A8H5J7N9_9HYPO/593-708    AC A0A8H5J7N9.1
#=GS A5DVG9_LODEL/685-795        AC A5DVG9.1
#=GS A0A1M3TMT4_ASPLC/665-727    AC A0A1M3TMT4.1
#=GS A0A061HCG2_BLUGR/439-559    AC A0A061HCG2.1
#=GS A0A8H8TZ48_9HELO/636-754    AC A0A8H8TZ48.1
#=GS A0A4Z1IH75_9HELO/661-783    AC A0A4Z1IH75.1
#=GS M3JUX9_CANMX/647-765        AC M3JUX9.1
#=GS A0A0B1P943_UNCNE/626-746    AC A0A0B1P943.1
#=GS A0A135UQG9_9PEZI/611-730    AC A0A135UQG9.1
#=GS A0A2V5GRN8_ASPV1/667-726    AC A0A2V5GRN8.1
#=GS N1Q1W8_DOTSN/609-740        AC N1Q1W8.1
#=GS A0A1Y2VVA9_9PEZI/596-715    AC A0A1Y2VVA9.1
#=GS A0A1S7HRH3_9SACH/896-1009   AC A0A1S7HRH3.1
#=GS A0A093Y150_9PEZI/652-773    AC A0A093Y150.1
#=GS A0A151GFS2_9HYPO/595-710    AC A0A151GFS2.1
#=GS A0A1B8DBT4_9PEZI/651-772    AC A0A1B8DBT4.1
#=GS A0A1G4K4H9_9SACH/902-1015   AC A0A1G4K4H9.1
#=GS W9YPL9_9EURO/639-751        AC W9YPL9.1
#=GS ORC1_YEAST/792-905          AC P54784.1
#=GS A0A094D6F3_9PEZI/652-773    AC A0A094D6F3.1
#=GS A0A8H4EEU4_9EURO/664-751    AC A0A8H4EEU4.1
#=GS A0A8J5QII9_9ASCO/684-809    AC A0A8J5QII9.1
#=GS A0A2T0FPH4_9ASCO/522-625    AC A0A2T0FPH4.1
#=GS W2S010_9EURO/643-759        AC W2S010.1
#=GS A0A194XK96_9HELO/601-718    AC A0A194XK96.1
#=GS B8LW87_TALSN/668-786        AC B8LW87.1
#=GS C5ME50_CANTT/704-827        AC C5ME50.1
#=GS S3D5I1_GLAL2/617-734        AC S3D5I1.1
#=GS A0A421JGL4_9ASCO/633-759    AC A0A421JGL4.1
#=GS A0A1L7X7W3_9HELO/629-747    AC A0A1L7X7W3.1
#=GS A0A7H9HRK4_9SACH/825-938    AC A0A7H9HRK4.1
#=GS A0A5M3YW09_ASPTE/663-783    AC A0A5M3YW09.1
#=GS A0A1E4S0P9_CYBJN/685-798    AC A0A1E4S0P9.1
#=GS A0A5E8BZ73_9ASCO/860-925    AC A0A5E8BZ73.1
#=GS A0A4V6TTP8_9ASCO/589-708    AC A0A4V6TTP8.1
#=GS A0A2H0ZC90_CANAR/636-753    AC A0A2H0ZC90.1
#=GS A0A0L1IRF2_ASPNO/642-729    AC A0A0L1IRF2.1
#=GS A0A507BF79_9PEZI/617-747    AC A0A507BF79.1
#=GS A0A1Q8RZ77_9PEZI/613-732    AC A0A1Q8RZ77.1
#=GS A0A3M9YCC5_9PEZI/546-666    AC A0A3M9YCC5.1
#=GS A0A194VH01_9PEZI/618-738    AC A0A194VH01.1
#=GS S3BZ28_OPHP1/647-777        AC S3BZ28.1
#=GS A0A1B8C562_9PEZI/651-772    AC A0A1B8C562.1
#=GS A0A8E0QZ81_9EURO/294-380    AC A0A8E0QZ81.1
#=GS A0A3F3QI74_9EURO/665-719    AC A0A3F3QI74.1
#=GS A0A0F8URU3_9EURO/664-751    AC A0A0F8URU3.1
#=GS ORC1_DEBHA/671-800          AC Q6BSE2.2
#=GS A0A420I3T0_9PEZI/615-735    AC A0A420I3T0.1
#=GS A0A4U0U2J4_9PEZI/619-674    AC A0A4U0U2J4.1
#=GS A0A1E4TRQ6_PACTA/645-762    AC A0A1E4TRQ6.1
#=GS A0A369GCS9_9HYPO/609-724    AC A0A369GCS9.1
#=GS A0A0L0N976_TOLOC/595-710    AC A0A0L0N976.1
#=GS A0A163CXR9_DIDRA/941-1076   AC A0A163CXR9.1
#=GS A0A0D1WW89_EXOME/625-737    AC A0A0D1WW89.1
#=GS W9IPQ3_FUSOX/593-708        AC W9IPQ3.1
#=GS A0A2G7G4R2_9EURO/659-747    AC A0A2G7G4R2.1
#=GS A0A8H3ISU3_9LECA/599-717    AC A0A8H3ISU3.1
#=GS A0A8H8D3R0_AJECA/693-791    AC A0A8H8D3R0.1
#=GS B2VU15_PYRTR/636-774        AC B2VU15.1
#=GS A0A1L9TVN1_9EURO/660-782    AC A0A1L9TVN1.1
#=GS A0A167WBE3_9EURO/692-822    AC A0A167WBE3.1
#=GS A0A0F4YVX3_TALEM/646-766    AC A0A0F4YVX3.1
#=GS A0A1L9VI21_ASPGL/655-781    AC A0A1L9VI21.1
#=GS A0A8H8RMG6_9HELO/625-743    AC A0A8H8RMG6.1
#=GS A0A1L9RVH5_ASPWE/666-790    AC A0A1L9RVH5.1
#=GS A0A0D2C6V5_9EURO/627-739    AC A0A0D2C6V5.1
#=GS C4XYD7_CLAL4/650-775        AC C4XYD7.1
#=GS A0A0G2EP46_9EURO/724-845    AC A0A0G2EP46.1
#=GS A0A066WY56_COLSU/610-729    AC A0A066WY56.1
#=GS A0A4T0VPI5_9PEZI/612-730    AC A0A4T0VPI5.1
#=GS A0A401KTJ4_ASPAW/665-719    AC A0A401KTJ4.1
#=GS A0A4Q4WH93_9PEZI/612-732    AC A0A4Q4WH93.1
#=GS A0A178E478_9PLEO/641-771    AC A0A178E478.1
#=GS A0A3M7B616_HORWE/626-684    AC A0A3M7B616.1
#=GS A0A178ZC96_9EURO/632-752    AC A0A178ZC96.1
#=GS G2QYL7_THETT/640-768        AC G2QYL7.1
#=GS G0S067_CHATD/635-767        AC G0S067.1
#=GS A0A1B8DTF1_9PEZI/651-772    AC A0A1B8DTF1.1
#=GS M7TGX0_EUTLA/557-679        AC M7TGX0.1
#=GS A0A1L9WVZ8_ASPA1/668-727    AC A0A1L9WVZ8.1
#=GS A0A8H5A079_FUSOX/575-690    AC A0A8H5A079.1
#=GS A0A0C7N4Y4_9SACH/852-965    AC A0A0C7N4Y4.1
#=GS A0A2T3AY26_AMORE/633-753    AC A0A2T3AY26.1
#=GS G2Y8H7_BOTF4/664-785        AC G2Y8H7.1
#=GS A0A2S4PT31_9PEZI/618-738    AC A0A2S4PT31.1
#=GS A0A6G1GH45_9PEZI/633-764    AC A0A6G1GH45.1
#=GS J6EQC4_SACK1/803-916        AC J6EQC4.1
#=GS A7ENL5_SCLS1/656-776        AC A7ENL5.1
#=GS A0A1Y2U9Y3_9PEZI/596-715    AC A0A1Y2U9Y3.1
#=GS A0A1X7R0F6_9SACH/821-934    AC A0A1X7R0F6.1
#=GS A0A8H6LSK2_FUSOX/514-629    AC A0A8H6LSK2.1
#=GS A0A8H4W518_9HELO/1196-1317  AC A0A8H4W518.1
#=GS A0A139IFY3_9PEZI/608-742    AC A0A139IFY3.1
#=GS G3YGG9_ASPNA/668-722        AC G3YGG9.1
#=GS A0A1J9QFZ3_9EURO/681-777    AC A0A1J9QFZ3.1
#=GS A0A4Z1JXV6_9HELO/662-784    AC A0A4Z1JXV6.1
#=GS A0A7R7XR03_9EURO/662-784    AC A0A7R7XR03.1
#=GS A0A2J6SC08_9HELO/616-736    AC A0A2J6SC08.1
#=GS A0A1E3PGG4_9ASCO/312-440    AC A0A1E3PGG4.1
#=GS A0A4Q4UT51_9PEZI/613-733    AC A0A4Q4UT51.1
#=GS A0A3M7NDJ9_9EURO/550-655    AC A0A3M7NDJ9.1
#=GS F9F1H9_FUSOF/506-621        AC F9F1H9.1
#=GS A0A1E3BM38_ASPCR/654-780    AC A0A1E3BM38.1
#=GS A0A165JJ68_XYLHT/642-760    AC A0A165JJ68.1
#=GS A0A1Z5SVJ5_HORWE/625-686    AC A0A1Z5SVJ5.1
#=GS A0A423X5H7_9PEZI/619-739    AC A0A423X5H7.1
#=GS A0A1R3S2U7_ASPC5/635-720    AC A0A1R3S2U7.1
#=GS A0A553IDB4_9PEZI/654-773    AC A0A553IDB4.1
#=GS A0A420YBE8_9PEZI/632-754    AC A0A420YBE8.1
#=GS A0A4Z1JKB2_9HELO/649-771    AC A0A4Z1JKB2.1
#=GS A0A8H3FK84_9LECA/611-738    AC A0A8H3FK84.1
#=GS A0A8H3ZK72_9PEZI/599-718    AC A0A8H3ZK72.1
#=GS K1X5S3_MARBU/638-756        AC K1X5S3.1
#=GS A1CQ43_ASPCL/662-752        AC A1CQ43.1
#=GS A0A094CEM5_9PEZI/646-767    AC A0A094CEM5.1
#=GS G8JMQ0_ERECY/907-1022       AC G8JMQ0.1
#=GS A0A5N6DZ65_ASPPA/659-747    AC A0A5N6DZ65.1
#=GS G8B660_CANPC/660-777        AC G8B660.1
#=GS A0A1W2TPJ5_ROSNE/612-731    AC A0A1W2TPJ5.1
#=GS A0A167B7D5_9PEZI/633-749    AC A0A167B7D5.1
#=GS A0A3N4LZP9_9PEZI/656-768    AC A0A3N4LZP9.1
#=GS A0A443HV20_BYSSP/667-790    AC A0A443HV20.1
#=GS A0A8H7GMZ0_9ASCO/449-571    AC A0A8H7GMZ0.1
#=GS A0A178AQ76_9PLEO/641-772    AC A0A178AQ76.1
#=GS A0A0D2CVR0_9EURO/633-747    AC A0A0D2CVR0.1
#=GS A2QQK2_ASPNC/604-658        AC A2QQK2.1
#=GS A0A512UFK6_9ASCO/669-792    AC A0A512UFK6.1
#=GS A0A8H6CDA9_9LECA/611-738    AC A0A8H6CDA9.1
#=GS A0A8H5JK47_9HYPO/575-690    AC A0A8H5JK47.1
#=GS A0A166UIG5_9PEZI/609-728    AC A0A166UIG5.1
#=GS A0A2H3I0V2_FUSOX/593-708    AC A0A2H3I0V2.1
#=GS A0A7R7VK16_ASPCH/654-780    AC A0A7R7VK16.1
#=GS A0A1G4M6S1_LACFM/867-980    AC A0A1G4M6S1.1
#=GS A0A3F2Y3S2_DEKBR/669-786    AC A0A3F2Y3S2.1
#=GS A0A559MKR6_9HELO/625-743    AC A0A559MKR6.1
#=GS A0A7H9B547_ZYGMR/873-986    AC A0A7H9B547.1
#=GS A0A2T3ACH9_9PEZI/618-739    AC A0A2T3ACH9.1
#=GS A0A1E3PBC1_WICAA/640-753    AC A0A1E3PBC1.1
#=GS A0A1V1TCX7_9FUNG/601-716    AC A0A1V1TCX7.1
#=GS A0A8J5P9B6_FUSOX/593-708    AC A0A8J5P9B6.1
#=GS A0A0H1B3D5_9EURO/658-757    AC A0A0H1B3D5.1
#=GS A0A0D2IEP5_9EURO/632-743    AC A0A0D2IEP5.1
#=GS A0A8H7TG44_9HELO/630-748    AC A0A8H7TG44.1
#=GS H0EX80_GLAL7/96-213         AC H0EX80.1
#=GS A0A225AXC7_9EURO/661-779    AC A0A225AXC7.1
#=GS A0A093XQD7_9PEZI/652-773    AC A0A093XQD7.1
#=GS A0A7C8MNR8_9PEZI/600-715    AC A0A7C8MNR8.1
#=GS W1QAS7_OGAPD/606-722        AC W1QAS7.1
#=GS A0A2V1APV5_9ASCO/625-742    AC A0A2V1APV5.1
#=GS A0A100IHX9_ASPNG/665-727    AC A0A100IHX9.1
#=GS A0A1D8PCY1_CANAL/672-795    AC A0A1D8PCY1.1
#=GS C9SJV7_VERA1/546-666        AC C9SJV7.1
#=GS A0A8H7E1J0_9EURO/637-768    AC A0A8H7E1J0.1
#=GS A0A0D1YZ08_9EURO/635-747    AC A0A0D1YZ08.1
#=GS Q7SH04_NEUCR/626-753        AC Q7SH04.2
#=GS G0V6S0_NAUCC/777-890        AC G0V6S0.1
#=GS A0A5N6JN16_MONLA/656-776    AC A0A5N6JN16.1
#=GS A0A367LAI7_9HYPO/608-723    AC A0A367LAI7.1
#=GS X0CE40_FUSOX/439-554        AC X0CE40.1
#=GS A0A094BHS5_9PEZI/654-775    AC A0A094BHS5.1
#=GS A0A2B7WU18_9EURO/684-812    AC A0A2B7WU18.1
#=GS A0A369H373_9HYPO/608-723    AC A0A369H373.1
#=GS A0A5N6ZDZ5_9EURO/663-748    AC A0A5N6ZDZ5.1
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A0A1E4TB41_9ASCO/365-471               ...............s-FLRSLPLSCHLALAAICNLVRRRNNKESTIEEVIDE...C....K....N...V....C..QMS...............................A.N...............KL...A...E......E.....Q....I........F......A......E.......L.......FESG..........RQ.....................L..PT-......-.-........-...-...-...-...L....MG..AIS....L...L..V..R..SGIV.......T.K....S.........M.........T.........P.....G..LLMGKVKLNISATDIQTAL............................................................................
A0A8H7YLW9_9EURO/687-785               .............qsl---RCLPLTGKVFLAGLLARIRRTGITESTFGDILDE...A....K....R...V....A..DAA...............................V.Av.............aGA...A...S......S.....N....L........K......A......Y.......L.......LQKG..........SD.....................I..RI-......-.S........R...V...C...A...M....RF..AAV....E...L..M..N..SGIL.......A.-....-.........-.........-.........-.....-..-------------------legelsakgs..................................................................
A0A317WCT8_9EURO/520-641               .............qsl---RCLPLSAKLFLAAMIARVRRTGISESTFGDVIDE...A....K....R...I....A..DAA...............................V.-...............--...-...-......-.....-....-........-......-......-.......-.......----..........--.....................-..---......-.-........-...-...-...-...-....--..---....-...-..-..-..----.......-.-....-.........-.........-.........-.....-..-------------------avagaagagvkefllaggngarvralgfaameltnsgvlaleyskgplgsaaiphrgdrsgkvrlrvaaedvkiaf
A0A010RVV9_9PEZI/611-730               ................QYLRSLPFGPKLFLCSLLVRMQRSGAAETTFGDVVDE...I....H....R...I....I..KLD...............................S.Ta............leST...P...L......G.....A....L........S......T......G.......P.......SGGD..........VG.....................Q..GNG......S.I........R...V...V...QslaL....PQ..AAL....E...L..M..G..AGII.......V.L....E.........A.........H.........K.....P..ERPSKARLAVGDEEVKMA-f...........................................................................
H2AW19_KAZAF/903-1007                  ...............a-YLNNCSLVTKLFLLAMLLKSHKMKEDEVKMKDVIEE...I....D....D...L....F..ESD...............................K.I...............SK...E...I......K.....D....I........R......G......A.......L.......FGNE..........EK.....................-..--I......N.V........E...V...I...A...W....DL..IAA....E...L..M..K..FDII.......E.K....S.........G.........-.........-.....-..---DSISFKISIDDIKE--gi..........................................................................
A0A4Z1KE78_9HELO/661-783               ................QYLRALPLATKMFLAALVLRLRRAGTGECLVGEVVDE...C....R....R...M....A..KLD...............................T.Ggsvv......gflltGA...G...A......A.....G....I........V......N......V.......G.......DKTR..........GK.....................Q..AGK......G.A........R...V...Q...G...M....GE..AAM....E...L..M..E..AGVI.......G.I....E.........V.........R.........K.....A..ERMGKVRLGIGEEDVKVA-f...........................................................................
A0A1Z5TQN4_HORWE/624-688               ...............a-YLRSLPLSSKLFLAALLARLRRTGITESTLADIVDE...A....K....R...M....-..SAM...............................A.Q...............NK...A...V......E.....-....-........-......-......-.......-.......----..........--.....................-..---......-.-........-...-...-...-...-....--..---....-...-..-..-..----.......-.-....-.........-.........-.........-.....-..-------------------ryllapdstssgql..............................................................
A0A3D8QWW3_9HELO/610-732               ................QYLRSLPFASKVLLAALLTKTRQTGLAESVMGDVLDK...A....K....Q...M....A..KMD...............................T.G...............SN...M...I......E.....H....L........L......R......D.......K.......ADGS..........SR....................sK..SSQ......Q.VgskgakipR...V...L...A...M....GT..SAV....D...L..M..D..AGII.......G.L....E.........A.........R.........R.....A..DRTGKVRLNIGEEDVRLA-f...........................................................................
A0A319DD48_9EURO/527-614               .............qsl---RCLPLSAKLFLAAMLARIHRTGISESTFGDVIDE...A....K....R...I....A..DAA...............................-.-...............--...-...-......-.....-....-........-......-......-.......-.......----..........--.....................-..---......-.-........-...-...-...-...-....--..---....-...-..-..-..----.......-.-....-.........-.........-.........-.....-..-------------------vavagaagagvkdfllaggngarvralgfaamelmnsgvlale.................................
L2GII6_COLFN/599-718                   ................QYLRSLAFAPKLLLSALLVKIQRNGTVETTFGDVMDE...M....Y....R...I....T..KID...............................T.Gg............ldPG...L...V......A.....A....M........V......S......G.......S.......SGAD..........LG.....................P..SRE......N.A........R...V...M...EamgL....RH..AAM....E...L..V..G..AGII.......V.L....E.........S.........Q.........R.....A..ERPSKMRLAVGDEELKMA-f...........................................................................
A0A074XBA6_9PEZI/609-656               ...............s-YLRSLPLASKLFLAALLGRIRRTGLTESTLGDIIDE...A....A....R...-....-..---...............................-.-...............--...-...-......-.....-....-........-......-......-.......-.......----..........--.....................-..---......-.-........-...-...-...-...-....--..---....-...-..-..-..----.......-.-....-.........-.........-.........-.....-..-------------------maalsslv....................................................................
A0A507QJ27_MONPU/704-835               .............qsl---RCLPLSAKLFLAAFLSRIRRTGISESTFGDILDE...A....K....R...I....A..DATv.............................aV.T...............GA...A...A......A.....G....V........K......D......F.......L.......LGNS..........NSnd.................egN..NGT......G.A........R...V...R...A...L....GF..AAM....E...L..M..N..SGVV.......A.L....E.........Ng......igLrghltggcgR.....G..DRSSRVRLRVATEDVRAA-f...........................................................................
N1J9P7_BLUG1/581-701                   ................NYLRELPLASKVFLVALVIRMRRNGTGEDTLGEVLDE...A....K....K...F....S..RQT...............................S.S..............dNK...-...-......-.....-....I........S......E......F.......L.......FKSK..........PEniagl...........spskrD..ISK......T.P........R...V...L...A...L....GK..SAI....S...L..M..E..AGII.......G.L....E.........T.........W.........K.....V..DRTAKVRLAVGEEDVKIA-f...........................................................................
A0A1L9P7G2_ASPVE/659-781               .............qsl---RCLPLSAKLFLAALLARVRRTGITESTFGDVMDE...A....K....R...I....A..DAA...............................V.Av.............aGA...A...G......A.....G....I........K......D......F.......L.......LAGG..........NG.....................A..---......-.-........R...V...R...A...L....GF..AAM....E...L..M..N..SGIL.......A.L....E.........Tss....rgaLgsa..aipsR.....G..DRSGKVRLRVAAEDVRAA-f...........................................................................
C1GWL4_PARBA/695-788                   .............qsl---RCLPLAGKVFLAGLLACIRRSGITESTFGDILDE...A....K....R...I....A..DAAv.............................aV.A...............GA...T...S......N.....N....L........K......Q......F.......L.......FQKG..........SD.....................V..RR-......-.S........R...V...C...A...M....RF..AAV....E...L..M..N..FGIL.......V.-....-.........-.........-.........-.....-..-------------------legel.......................................................................
A0A7D8UN85_9HELO/636-754               ................QYLRGLPLSAKILLAALMAKTRRTGVAESVLGDVLDE...A....R....R...M....A..KMD...............................T.G...............GKtleY...L......M.....K....P........D......S......I.......V.......STKGm........vLK.....................Q..PMK......A.P........R...V...L...A...M....GM..SAV....D...L..M..E..AGII.......G.L....E.........A.........R.........K.....A..DRTGKIRLSIGDEDLKLA-f...........................................................................
A0A1E4SML8_9ASCO/653-777               ................QFLVTLPFASKLFLQAVLLRMKRSGLAENSLGDIIDE...M....K....N...S....L..QLL...............................T.Sdkg........tnvlNP...L...G......A.....N....I........Tl....lD......L.......L.......YGNS..........LA.....................D..SST......K.L........N...I...R...S...W....KFkhLVN....E...L..V..E..YGIL.......M.Q....Q.........N.........V.........P.....G..ERYRLIQLNISEEELSLA-l...........................................................................
A0A8H7J2U5_9PLEO/934-1069              .............qal---RALPLVSKVFLAALLARIRRTGIGEAVLGDVVDE...V....K....K...L....G..FMSqlqpvhd.................yllapegI.N...............GS...F...N......L.....D....V........Q......S......T.......T.......PSEN..........TEpaei.............askhA..KLK......A.A........R...V...L...G...L....AS..AAT....H...L..A..E..AGII.......G.V....E.........A.........R.........H.....G..ERVGRVRLGVGEDEVRLAL............................................................................
A0A3M7BFC3_HORWE/624-679               ...............a-YLRSLPLSSKLFLAALLARLRRTGITESTLADIVDE...A....K....R...M....S..AM-...............................A.Q...............--...-...-......-.....-....-........-......-......-.......-.......----..........--.....................-..---......-.-........-...-...-...-...-....--..---....-...-..-..-..----.......-.-....-.........-.........-.........-.....-..-------------------nralehylla..................................................................
A0A8A3P4U5_9HELO/655-775               ................QYLRALPLVAKLFLAALIFRLRRAGTGECLMGEVVDE...C....R....R...M....A..KLD...............................T.S...............GS...V...V......G.....Y....L........-......-......-.......L.......VGEGngv....gggEKtr.................grA..AGK......G.A........R...V...Q...G...M....GE..AAM....E...L..M..E..AGVI.......G.V....E.........V.........R.........K.....A..ERMGKVRLGIGEEDVKVA-f...........................................................................
G4MNI2_MAGO7/635-772                   ................QYLRALPFSSRLLLAALLVRVTRTGLAESTYGDVLEE...M....Q....R...A....V..KFAsgsrqve................lldrrridA.A...............GR...Y...V......A.....D....P........A......A......A.......A.......SEEGggw...vsssAK.....................K..KKD......Q.Vm......hR...L...A...G...L....SL..AAV....E...L..T..G..AGIV.......N.L....E.........A.........H.........R.....A..ERPSKIRLAVGDEEVRLA-f...........................................................................
L8G7N2_PSED2/651-772                   ..............qh--LRGLPLASKLLLASLLARIRRTGIGESFIGEVIEE...A....KriskM...V....V..DIE...............................T.L...............GF...L...L......T.....E....I........S......P......T.......Agg...gkAHLD..........RK.....................N..QRD......A.P........R...V...H...A...M....GT..AAI....E...L..M..E..AGII.......G.F....E.........A.........R.........K.....G..DRVAKVRLCIGEGDVKLAL............................................................................
A0A364KQ55_9EURO/665-783               .............qsl---RCLPLAGKLFLAALLARVRRTGISESTMGDVLDE...A....R....R...I....A..DAA...............................V.A...............VA...G...La....gS.....S....I........K......N......Y.......L.......LGKD..........NP.....................G..ARV......H.A........M...V...F..aA...M....EL..MNS....G...V..ValE..TGVG.......I.R....V.........R.........G.........G.....G..DRSSKVRLRIAAEEVKSA-f...........................................................................
A0A5N6KQY5_9ROSI/627-756               ................QYIRCLPLATKLFLAALLARTRRTGLAEALLGDVVDE...A....K....R...I....A..GMSteapdvee...............fllhgagrA.A...............DA...L...S......V.....G....P........S......K......A.......R.......RDRD..........RD.....................G..QEK......A.S........R...V...L...G...M....GA..ATM....E...L..L..E..AGLL.......V.V....E.........E.........R.........K.....G..ERAAKVRLLIGEDEVKLAL............................................................................
A0A179V2I7_BLAGS/682-779               .............qsl---RCLPLTGKVFLAGLLARIRRTGITESTFGDILDE...A....K....R...I....A..DAAv.............................aV.A...............GA...A...S......N.....N....L........R......E......Y.......L.......LQKG..........SD.....................M..RRS......-.-........H...V...C...A...M....RF..AAV....E...L..M..N..SGIL.......A.-....-.........-.........-.........-.....-..-------------------legessvkg...................................................................
A0A8H5RZI0_9HYPO/593-708               ...............q-HLRSLPLMSKLVMAALLLRIRRTGLAETTFGDTLDE...I....H....R...A...cL..RAP...............................A.A...............LP...G...V......A.....T....V.......lN......N......G.......L.......KGSQ..........MG.....................S..QRQ......M.T........R...P...G...H...I....HT..AAL....E...L..V..A..AGLV.......N.L....E.........A.........Q.........R.....A..ERSSKLRLSIADDEVKMAL............................................................................
A0A2K0WD98_GIBNY/593-708               ...............q-HLRSLPLMSKLVMAALLLRIRRTGLAETTFGDTLDE...I....H....R...A...cL..RAP...............................A.A...............LP...G...V......A.....A...vL........N......N......G.......L.......KGTQ..........IG.....................S..QRP......M.T........R...P...G...H...I....HT..AAL....E...L..V..A..AGLI.......N.L....E.........A.........Q.........R.....A..ERSSKLRLSIADDEVKMAL............................................................................
A0A074VCV2_9PEZI/607-653               ...............a-YLRSLPLASKLFLAALLGRIRRTGLTESTLGDIIDE...A....A....R...-....-..---...............................-.-...............--...-...-......-.....-....-........-......-......-.......-.......----..........--.....................-..---......-.-........-...-...-...-...-....--..---....-...-..-..-..----.......-.-....-.........-.........-.........-.....-..-------------------maalssl.....................................................................
N1RJL5_FUSC4/575-690                   ...............q-HLRSLPLMSKLVMAALLLRIRRTGLAETTFGDTLDE...I....H....R...A...cL..RAP...............................A.A...............LP...G...V......A.....A...vL........N......N......G.......L.......KGTQ..........MG.....................S..QRP......M.T........R...P...G...H...I....HT..AAL....E...L..V..A..AGLI.......N.L....E.........A.........Q.........R.....A..ERSSKLRLSIADDEVKMAL............................................................................
A0A8H6V9H3_9EURO/664-785               ..............qs--LRSLPLSAKLFLAALLARVKRTGITESTFGDVIDE...A....K....R...I....A..DAA...............................V.A...............-V...A...S......T.....G....I........K......D......F.......L.......LAGN..........NG.....................-..---......-.A........R...V...R...A...L....GF..AAM....E...L..M..N..SGVL.......A.-....-.........-.........-.........-.....-..-------------------lengagvkgplggstipnrgdrsgkvrlrvapedvraaf.....................................
A0A319CXT8_9EURO/667-726               .............qsl---RCLPLAAKLFLAALLARVRRTGISESTVGDVIDE...A....K....R...I....A..DA-...............................-.-...............--...-...-......-.....-....-........-......-......-.......-.......----..........--.....................-..---......-.-........-...-...-...-...-....--..---....-...-..-..-..----.......-.-....-.........-.........-.........-.....-..-------------------avavasaagvgirefl............................................................
A0A8H7TQJ4_BIOOC/503-617               ...............q-HLKSLPLVSKLLMAAVLLRIRRTGLAETTFGETLDE...L...hR....A...N....L..RAP...............................T.S...............NA...G...L......A.....Q....I........L......P......A.......S.......TKGS..........HV.....................G..SQN......L.G........R...P...A...H...I....HT..AAL....E...L..V..A..AGLI.......N.L....E.........A.........Q.........R.....A..ERSSRLRLAIADDEVKMAL............................................................................
G3AY54_CANTC/630-753                   ................QYVASLSMASKLILCALLLRQRRSGLAENPLGDIIDE...I....K....I...L....L..RMA...............................S.Skslr......lsgtiSG...H...-......I.....D....V........A......E......A.......L.......LDGRm........tND.....................Q..AKT......S.I........R...I...E...N...F....KF..LIF....E...L..I..E..NGIL.......N.A....Q.........D.........I.........K.....S..ERYRLVSLNVSQDEVMST-l...........................................................................
#=GC seq_cons                          .................aLRuLPLuuKLhLAALLsRhRRTGluEoohGDVlDE...s....+....R...h....s..chs...............................s.s...............st...h...h......t.....t....l........p......p......h.......h.......htts..........tt.....................t..ttt......t.h........R...l...h...u...h....th..ush....-...L..h..p..uGIl.......s.h....p.........s.........h.........+.....u..-Rsu+lRLslu---l+.A.h...........................................................................
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