#=GF ID ORF_12_N
#=GF AC PF18042.5
#=GF DE ORF 12 gene product N-terminal
#=GF AU El-Gebali S;0000-0003-1378-5495
#=GF AU Smart A;0000-0002-6965-5633
#=GF SE ECOD:EUF03056
#=GF GA 26.70 26.70;
#=GF TC 26.70 27.00;
#=GF NC 26.60 25.10;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP Domain
#=GF CL CL0051
#=GF RN [1]
#=GF RM 23897479
#=GF RT Structural and mechanistic studies of the orf12 gene product
#=GF RT from the clavulanic acid biosynthesis pathway.
#=GF RA Valegard K, Iqbal A, Kershaw NJ, Ivison D, Genereux C, Dubus A,
#=GF RA Blikstad C, Demetriades M, Hopkinson RJ, Lloyd AJ, Roper DI,
#=GF RA Schofield CJ, Andersson I, McDonough MA;
#=GF RL Acta Crystallogr D Biol Crystallogr. 2013;69:1567-1579.
#=GF DR INTERPRO; IPR040846;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC This is the N-terminal domain of Streptomyces clavuligerus ORF
#=GF CC 12 gene product, which is directly involved in biosynthesis of
#=GF CC Clavulanic acid (CA). The N-terminal domain consists of one
#=GF CC four-stranded antiparallel beta-sheet surrounded by four
#=GF CC alpha-helices and folds similarly to steroid isomerases and
#=GF CC polyketide cyclases (PKTC). However, the N-terminal domain has
#=GF CC no apparent polar-lined active-site pocket or conserved
#=GF CC catalytic residues analogous to those of either the steroid
#=GF CC isomerases or PKTCs. ORF 12 has 2 binding sites, CA is able to
#=GF CC bind both to an active site and between the two domains. The
#=GF CC active site pocket is lined by residues from both the N- and the
#=GF CC C-terminal domains (His88, Ser173, Thr209, Ser234, Ser278,
#=GF CC Met383, Phe374, Ala376 and Phe385). The C-2 carboxylate of CA is
#=GF CC positioned deep in the pocket, making electrostatic interactions
#=GF CC with Lys375, Arg418 and Lys89. Lys89 is located in strand beta-2
#=GF CC of the N-terminal domain and may also be involved in the
#=GF CC beta-lactam core-binding region, including the residues Lys89 as
#=GF CC well as Arg418 [1].
#=GF SQ 201
#=GS X8FA51_MYCUL/34-122 AC X8FA51.1
#=GS A0A0A0BZ64_9CELL/37-130 AC A0A0A0BZ64.1
#=GS A0A171DP00_9ACTN/62-151 AC A0A171DP00.1
#=GS W5W8E7_9PSEU/25-115 AC W5W8E7.1
#=GS A0A7K1UHJ3_9MICC/65-158 AC A0A7K1UHJ3.1
#=GS A0A7I7K8X8_9MYCO/50-137 AC A0A7I7K8X8.1
#=GS A0A0M8MMU6_9MICO/3-95 AC A0A0M8MMU6.1
#=GS A0A0G3IQ95_9MYCO/44-131 AC A0A0G3IQ95.1
#=GS A0A7I7NSC1_9MYCO/34-123 AC A0A7I7NSC1.1
#=GS A0A0W7WD38_9MICO/62-157 AC A0A0W7WD38.1
#=GS A0A6N9YGE9_9ACTN/16-108 AC A0A6N9YGE9.1
#=GS A0A1S1NFN9_9MYCO/51-140 AC A0A1S1NFN9.1
#=GS A0R570_MYCS2/27-116 AC A0R570.1
#=GS A0A6M5IWR7_9MICO/86-181 AC A0A6M5IWR7.1
#=GS A0A7I9XWP8_9MYCO/3-92 AC A0A7I9XWP8.1
#=GS A0A132PM56_9MYCO/31-120 AC A0A132PM56.1
#=GS A0A164NX58_9NOCA/24-112 AC A0A164NX58.1
#=GS A0A1R3XE50_9MICO/1-90 AC A0A1R3XE50.1
#=GS A0A6N4W7N8_9MYCO/1-76 AC A0A6N4W7N8.1
#=GS A0A6L9S9Y0_9ACTN/67-160 AC A0A6L9S9Y0.1
#=GS A0A5C4WFA7_9ACTN/64-153 AC A0A5C4WFA7.1
#=GS B5GLD6_STRCL/24-114 AC B5GLD6.1
#=GS A0A895XQR4_9ACTN/48-137 AC A0A895XQR4.1
#=GS A0A329QEW1_9ACTN/49-142 AC A0A329QEW1.1
#=GS Q9CBI7_MYCLE/51-140 AC Q9CBI7.1
#=GS A0A1Z4EPA5_9MYCO/26-115 AC A0A1Z4EPA5.1
#=GS A0A542YPH7_9MICO/94-192 AC A0A542YPH7.1
#=GS B0RFF5_CLAMS/3-96 AC B0RFF5.1
#=GS A0A193LJP8_9GAMM/125-217 AC A0A193LJP8.1
#=GS A0A160DSP2_9GAMM/45-125 AC A0A160DSP2.1
#=GS W9AYB5_MYCCO/53-142 AC W9AYB5.1
#=GS A0A378TF18_9MYCO/46-135 AC A0A378TF18.1
#=GS A0A1H8QD37_9PSEU/6-96 AC A0A1H8QD37.1
#=GS A0A841DDB9_PLAVE/46-135 AC A0A841DDB9.1
#=GS A0A0T1WF29_9MYCO/37-126 AC A0A0T1WF29.1
#=GS A0A6N4VHT3_9MYCO/51-138 AC A0A6N4VHT3.1
#=GS A0A1A1ZBA3_9MYCO/35-122 AC A0A1A1ZBA3.1
#=GS A0A7W7QV38_9ACTN/48-137 AC A0A7W7QV38.1
#=GS A0A1H8J442_9ACTN/52-141 AC A0A1H8J442.1
#=GS A0A7I7S4P1_9MYCO/38-127 AC A0A7I7S4P1.1
#=GS A0A1A3PHS8_9MYCO/51-139 AC A0A1A3PHS8.1
#=GS A0A1X0CTS3_9MYCO/32-118 AC A0A1X0CTS3.1
#=GS A0A848K9T4_9NOCA/108-196 AC A0A848K9T4.1
#=GS A0A7W8EFM0_9ACTN/47-136 AC A0A7W8EFM0.1
#=GS A0A438ME53_9ACTN/46-135 AC A0A438ME53.1
#=GS A0A0N9XM93_MYCFO/55-143 AC A0A0N9XM93.1
#=GS A0A1X1RA19_MYCFA/45-134 AC A0A1X1RA19.1
#=GS A0A5N0T666_9MICO/35-129 AC A0A5N0T666.1
#=GS A0A1X2C947_9MYCO/51-140 AC A0A1X2C947.1
#=GS A0A1B1NFI9_9MICO/66-162 AC A0A1B1NFI9.1
#=GS A0A1X2C350_9MYCO/51-140 AC A0A1X2C350.1
#=GS V5XJA6_MYCNE/49-138 AC V5XJA6.1
#=GS A0A1X0H1X1_9MYCO/48-135 AC A0A1X0H1X1.1
#=GS I4BQ48_MYCCN/52-139 AC I4BQ48.1
#=GS A0A7I7MWS6_9MYCO/1-76 AC A0A7I7MWS6.1
#=GS A0A1V9KL92_9ACTN/18-110 AC A0A1V9KL92.1
#=GS A0A5D0QL59_9ACTN/32-122 AC A0A5D0QL59.1
#=GS A0A1E3SEG7_MYCIE/47-136 AC A0A1E3SEG7.1
#=GS A0A1A3N106_MYCAS/35-124 AC A0A1A3N106.1
#=GS A0A6G7XHD9_9MICO/48-145 AC A0A6G7XHD9.1
#=GS A0A239V4Q0_9MICO/41-132 AC A0A239V4Q0.1
#=GS A1TG24_MYCVP/52-139 AC A1TG24.1
#=GS A0A1X0DQ25_MYCHE/51-140 AC A0A1X0DQ25.1
#=GS A0A5D0QEW8_9ACTN/41-130 AC A0A5D0QEW8.1
#=GS A0A1R4FU27_9ACTO/65-160 AC A0A1R4FU27.1
#=GS A0A2R5H4K5_9MYCO/34-123 AC A0A2R5H4K5.1
#=GS A0A0W7WCP4_9MICO/57-152 AC A0A0W7WCP4.1
#=GS X8B813_MYCAV/33-122 AC X8B813.1
#=GS A0A5N5VB55_MYCPH/23-110 AC A0A5N5VB55.1
#=GS A0A8J3RMW6_9ACTN/46-135 AC A0A8J3RMW6.1
#=GS A0A4P8KP64_9MICO/43-137 AC A0A4P8KP64.1
#=GS A0A346Y573_9ACTN/60-152 AC A0A346Y573.1
#=GS A0A4R8R0X9_9MYCO/45-133 AC A0A4R8R0X9.1
#=GS A0A7W5VE85_9ACTN/46-135 AC A0A7W5VE85.1
#=GS D1BK86_SANKS/39-132 AC D1BK86.1
#=GS A0A2W2EB24_9ACTN/81-169 AC A0A2W2EB24.1
#=GS A0A1B7LX78_9MICC/49-145 AC A0A1B7LX78.1
#=GS A0A0A0BT01_9CELL/94-186 AC A0A0A0BT01.1
#=GS A0A2P8DJZ0_9ACTN/104-197 AC A0A2P8DJZ0.1
#=GS A0A0S9DWB3_9MICO/57-149 AC A0A0S9DWB3.1
#=GS A0A498R257_9MYCO/53-142 AC A0A498R257.1
#=GS B2HJ33_MYCMM/53-141 AC B2HJ33.1
#=GS A0A1B7LWH1_9MICC/52-147 AC A0A1B7LWH1.1
#=GS A0A7I7SIL3_9MYCO/5-93 AC A0A7I7SIL3.1
#=GS F6EGX8_HOYSD/63-157 AC F6EGX8.1
#=GS A0A4U3MQ40_9ACTN/42-131 AC A0A4U3MQ40.1
#=GS A0A429B4E2_9ACTN/48-137 AC A0A429B4E2.1
#=GS A0A0W8IA89_9MICO/69-162 AC A0A0W8IA89.1
#=GS A0A7W9MIM0_9ACTN/47-136 AC A0A7W9MIM0.1
#=GS A0A1Q4HEC4_9MYCO/42-131 AC A0A1Q4HEC4.1
#=GS A0A2S8LIS4_9MYCO/74-163 AC A0A2S8LIS4.1
#=GS A0A852SIW3_9MICO/55-151 AC A0A852SIW3.1
#=GS A0A0D1JMD8_9MYCO/31-119 AC A0A0D1JMD8.1
#=GS A0A516G893_9MICO/103-199 AC A0A516G893.1
#=GS A0A1X1QYJ8_MYCBE/50-139 AC A0A1X1QYJ8.1
#=GS X8C7M2_MYCXE/33-120 AC X8C7M2.1
#=GS A0A251XNX8_CLAMM/54-148 AC A0A251XNX8.1
#=GS A0A554UWR9_9ACTN/34-127 AC A0A554UWR9.1
#=GS I2A818_9MYCO/51-140 AC I2A818.1
#=GS A0A7G1I937_MYCKA/25-114 AC A0A7G1I937.1
#=GS A0A3S4S512_MYCCI/49-138 AC A0A3S4S512.1
#=GS A0A8J8HA20_9ACTN/30-119 AC A0A8J8HA20.1
#=GS O06155_MYCTU/49-138 AC O06155.2
#=GS X8FM64_MYCUL/1-42 AC X8FM64.1
#=GS D2ARL9_STRRD/46-135 AC D2ARL9.1
#=GS A0A852V721_9ACTN/76-165 AC A0A852V721.1
#=GS A0A2A9D409_9MICO/65-158 AC A0A2A9D409.1
#=GS A0A438MJG7_9ACTN/32-122 AC A0A438MJG7.1
#=GS A0A0D0I007_9MICO/54-149 AC A0A0D0I007.1
#=GS A0A2P8GRR3_9MICO/4-97 AC A0A2P8GRR3.1
#=GS I0RMF6_MYCXE/1-82 AC I0RMF6.1
#=GS A0A3N6GD36_9ACTN/24-115 AC A0A3N6GD36.1
#=GS A0A7I7XMY9_9MYCO/48-137 AC A0A7I7XMY9.1
#=GS D2AXP4_STRRD/32-122 AC D2AXP4.1
#=GS A0A2V1K806_9ACTO/67-161 AC A0A2V1K806.1
#=GS A0A3M2JEV3_9CELL/108-203 AC A0A3M2JEV3.1
#=GS A0A2G5P7G2_9MYCO/29-118 AC A0A2G5P7G2.1
#=GS A0A7X5TT83_9MICO/57-155 AC A0A7X5TT83.1
#=GS A0A1G8V0T2_9ACTN/46-135 AC A0A1G8V0T2.1
#=GS A0A0M2K596_9MYCO/23-110 AC A0A0M2K596.1
#=GS A0A4Z1E6G3_9MICO/67-160 AC A0A4Z1E6G3.1
#=GS A0A5J6V8A4_9MICO/93-187 AC A0A5J6V8A4.1
#=GS A0A557XZ17_9MYCO/51-140 AC A0A557XZ17.1
#=GS A0A132TAE9_9MYCO/23-110 AC A0A132TAE9.1
#=GS A0A1X1SYJ5_9MYCO/52-140 AC A0A1X1SYJ5.1
#=GS A0A7W9GCV9_9ACTN/44-133 AC A0A7W9GCV9.1
#=GS A0A1V0AGH8_9ACTN/43-132 AC A0A1V0AGH8.1
#=GS A0A8J3T1C8_9ACTN/46-135 AC A0A8J3T1C8.1
#=GS A0A1E8Q5P6_9MYCO/38-127 AC A0A1E8Q5P6.1
#=GS A0A1X2LUJ8_9MYCO/56-145 AC A0A1X2LUJ8.1
#=GS X7XRV6_MYCKA/1-46 AC X7XRV6.1
#=GS A0A8J4A0R9_9ACTN/57-147 AC A0A8J4A0R9.1
#=GS A0A1H6E5Q7_9ACTN/42-131 AC A0A1H6E5Q7.1
#=GS G9PGL4_9ACTO/92-185 AC G9PGL4.1
#=GS A0A0Q2QHU4_MYCGO/51-140 AC A0A0Q2QHU4.1
#=GS A0A0P0ED64_9MICO/42-136 AC A0A0P0ED64.1
#=GS A0A3N6D0W8_9ACTN/22-113 AC A0A3N6D0W8.1
#=GS A0A1H1A199_9ACTN/55-144 AC A0A1H1A199.1
#=GS A0A0D0H7I1_9MICO/40-135 AC A0A0D0H7I1.1
#=GS A0A4Q2M200_9MICO/34-127 AC A0A4Q2M200.1
#=GS A0A1X1TIK8_9MYCO/50-139 AC A0A1X1TIK8.1
#=GS A0A3B0BA12_9MICO/31-125 AC A0A3B0BA12.1
#=GS A0A1A0P978_9MYCO/32-121 AC A0A1A0P978.1
#=GS A0A7X8TKS2_9MICC/76-169 AC A0A7X8TKS2.1
#=GS A0A318ADW9_9MICC/84-180 AC A0A318ADW9.1
#=GS K5BAD7_MYCHD/10-98 AC K5BAD7.1
#=GS A0A7I7Z1D9_9MYCO/32-121 AC A0A7I7Z1D9.1
#=GS A0A1E3RT17_9MYCO/22-109 AC A0A1E3RT17.1
#=GS A0A0D0INK9_9MICO/59-154 AC A0A0D0INK9.1
#=GS A0A5S4GGQ0_9ACTN/92-181 AC A0A5S4GGQ0.1
#=GS C7N0A8_SACVD/15-107 AC C7N0A8.1
#=GS A0A3N2D8K0_9MICO/70-163 AC A0A3N2D8K0.1
#=GS A0A5S9MVF4_MYCVN/36-123 AC A0A5S9MVF4.1
#=GS A0A849BNB9_9ACTN/50-143 AC A0A849BNB9.1
#=GS Q743X5_MYCPA/25-114 AC Q743X5.1
#=GS A0A7I7SN54_9MYCO/40-127 AC A0A7I7SN54.1
#=GS A0A7J0C5B4_9ACTN/23-113 AC A0A7J0C5B4.1
#=GS A0A1A2G1E5_9MYCO/51-140 AC A0A1A2G1E5.1
#=GS A0A0Q9D6S3_9CELL/30-126 AC A0A0Q9D6S3.1
#=GS A0A100VXA7_9MYCO/38-127 AC A0A100VXA7.1
#=GS A0A1A3C7D3_9MYCO/50-137 AC A0A1A3C7D3.1
#=GS A0A2T0MLS2_9ACTN/49-138 AC A0A2T0MLS2.1
#=GS A0A7W8D527_9GAMM/60-149 AC A0A7W8D527.1
#=GS A0A1R1IAI3_9ACTN/52-143 AC A0A1R1IAI3.1
#=GS U2YKT1_9MICO/56-148 AC U2YKT1.1
#=GS A0A0D5AIM5_9NOCA/31-124 AC A0A0D5AIM5.1
#=GS A0A7K3LY48_9ACTN/54-146 AC A0A7K3LY48.1
#=GS K6WGG5_9MICO/50-140 AC K6WGG5.1
#=GS A0A4R4MYI2_9ACTN/47-136 AC A0A4R4MYI2.1
#=GS A0A7G9S5Z3_9MICO/34-129 AC A0A7G9S5Z3.1
#=GS A0A7W8EDF8_9ACTN/33-122 AC A0A7W8EDF8.1
#=GS A0A4R5C990_9ACTN/71-164 AC A0A4R5C990.1
#=GS A0A2Y9AA67_9MICO/54-146 AC A0A2Y9AA67.1
#=GS A0A516X6I1_9ACTN/57-150 AC A0A516X6I1.1
#=GS A0A7W7RRC7_9ACTN/44-133 AC A0A7W7RRC7.1
#=GS A0A5C8HNG4_9MICO/50-144 AC A0A5C8HNG4.1
#=GS A0A1X1RWW8_MYCCE/51-140 AC A0A1X1RWW8.1
#=GS A0A2U0H3S9_9MICO/46-137 AC A0A2U0H3S9.1
#=GS A0A646KKS9_STRJU/18-110 AC A0A646KKS9.1
#=GS A0A4S5E698_9MICC/57-150 AC A0A4S5E698.1
#=GS F6EHC3_HOYSD/49-138 AC F6EHC3.1
#=GS A0A4R4PCF3_9ACTN/39-108 AC A0A4R4PCF3.1
#=GS A0A0J6WB15_MYCCU/36-123 AC A0A0J6WB15.1
#=GS A0A2A7NGY9_MYCAG/28-117 AC A0A2A7NGY9.1
#=GS A0A7G7BN89_9ACTN/24-113 AC A0A7G7BN89.1
#=GS A0A7W0HQ83_9ACTN/29-118 AC A0A7W0HQ83.1
#=GS A0A4Y9MY93_9MYCO/37-126 AC A0A4Y9MY93.1
#=GS F5YS86_MYCSD/29-118 AC F5YS86.1
#=GS A0A239BGQ3_9ACTN/46-135 AC A0A239BGQ3.1
#=GS A0A444PRN8_9MICO/56-149 AC A0A444PRN8.1
#=GS G7CF05_MYCT3/49-138 AC G7CF05.1
#=GS A0A2V5L5M5_9MICC/17-110 AC A0A2V5L5M5.1
#=GS A0A0K1PHY3_9DELT/33-125 AC A0A0K1PHY3.1
#=GS A0A7W9IIK1_9ACTN/61-150 AC A0A7W9IIK1.1
#=GS A0A1V0AA61_9ACTN/35-125 AC A0A1V0AA61.1
#=GS A0A1A0MHI6_9MYCO/51-140 AC A0A1A0MHI6.1
#=GS A0A0T2L0S9_9MICO/58-150 AC A0A0T2L0S9.1
#=GS A0A0I9U0C3_9MYCO/51-140 AC A0A0I9U0C3.1
#=GS A0A7I7XQI6_9MYCO/3-92 AC A0A7I7XQI6.1
#=GS A0A8J3AA65_9ACTN/50-140 AC A0A8J3AA65.1
#=GS A0A5A7WZV7_9MYCO/1-74 AC A0A5A7WZV7.1
X8FA51_MYCUL/34-122 ....dtv---TPPGLRAQQTMDMLNSDWP.I..GPAGV.....A....TLAAPSKVDS--.-.--.VEATME.GLWWD.RP.F.AL.DSVDI...S..AS....V....ATLHLT.S.SYGARQDI.RLHTDDGGWV...............................
A0A0A0BZ64_9CELL/37-130 .......LPDHPAGRAAEWVLDLLNGAGP.P.aLTEDD.....L....ERFDDAFVEQIS.R.AD.LEEVFV.ELHGD.GP.W.TV.TDVGG...V..EP....A....VVALLD.S.PTA-EYEM.TVVVDDDGRI...............................
A0A171DP00_9ACTN/62-151 .......IPDSPAGRQLRWFLGAPDR-AP.L..SGSEL.....A....EHVEAAFLAELT.V.EK.FNAFLA.DVRGL.--.-.TL.EKLTE...V..TP....T....ALTGTG.R.IGKEEVTV.QLRVNAQGKI...............................
W5W8E7_9PSEU/25-115 ....atp---TTAVDQLRWFVDATNR-AP.I..SDSEL.....Q....HHFSPALLNAAG.GtAG.INATFT.Q---L.GP.L.EF.GQVKQ..dQ..PN....S....AAATAT.G.GAG-EILV.TVHTDTNGL-l..............................
A0A7K1UHJ3_9MICC/65-158 .......LPDTAAGQTAEYVLEVINAEQD.S..TAEDW.....Q....GRLSDSFRQELD.E.AD.VAEFINqQLRPG.SP.W.TA.TGHQG...S..ET....L....SSTRIE.G.AQG-ALDL.QLEVNSEQ--el.............................
A0A7I7K8X8_9MYCO/50-137 .....ai--NTPQGLRAKQTMDMLNSDWP.I..GEVGV.....R....TLAAPEIVEH--.-.--.VGVTLD.RMWWD.RP.F.TV.RDVEV...G..AG....N....ATLHIT.T.SYGVQQTI.DLRTDDT---ts.............................
A0A0M8MMU6_9MICO/3-95 .......IPDTPVGTQAQWVIDEINAGEA.S..SAGEV.....E....ARFDETALAELS.A.DD.LLAVFG.ELRTL.GP.W.TV.TSYEG...D..DA....Q....AVAGIS.A.GTT-ALDM.SVAVSAAGR-m..............................
A0A0G3IQ95_9MYCO/44-131 ......l--NTPQGVRAKQVMDMLNSDWP.I..GNQSV.....K....TLATPDLVDP--.-.--.VAHTMD.SLWWD.RP.Y.TL.AGVEV...G..AN....V....ATLHML.T.SYGARQDI.DLRIGDD---tfv............................
A0A7I7NSC1_9MYCO/34-123 .....id-TRTPPGLRAQQTLDMLNSDWP.I..GPVGV.....R....TLAAPDNVGS--.-.--.VETIME.GLWWD.RP.F.AL.DGVDI...S..AS....V....ATLHLV.S.SYGARQDI.RIHTDDDGRV...............................
A0A0W7WD38_9MICO/62-157 .......IPDTQVGDTMQWAIDMLNSSED.P..TVAEI.....E....AKFSDQFLKAVP.V.EE.FLAQTNtAIRPA.GP.F.EL.SAYEE..aD..EL....S....AVATLE.G.EVGGAVQL.QVGLNEQGEI...............................
A0A6N9YGE9_9ACTN/16-108 .......IPADAVGSQVKWVLDQLGAGSG.P..DTETA.....Q....ERFSDEFLAHVP.A.EE.MDATFA.QLRAL.GP.F.TP.TSYSS...R..GD....E....AVVMLD.G.ADDTAWRL.SVAIDND---ei.............................
A0A1S1NFN9_9MYCO/51-140 .....id-TKTPPGLRAKQTVDMLNSDWP.I..GPVGV.....R....TLATPDMVDS--.-.--.VVTTME.GLWWD.RP.F.TF.ESVDI...H..AG....A....ATLHLV.T.SYGARQDI.ELHTDDNGLV...............................
A0R570_MYCS2/27-116 .....id-TNTPPGLRAKQTMDMLNSDWP.I..GPVSV.....G....TLASPEKIDD--.-.--.VGVKMD.TIWWD.RP.F.KV.TSVEI...G..AG....Q....ATLHVL.T.SYNVAQNI.ELRTNDAGLV...............................
A0A6M5IWR7_9MICO/86-181 ......l-PEGVLGEQAGWVLRALNGEIP.EkdQRADV.....E....ARFAPEALESIS.P.DE.LVAVFG.QLGAQ.GP.W.IP.TAVEA...V..GT....Q....AVITIT.P.ASGDALDM.QLALDAEDR-l..............................
A0A7I9XWP8_9MYCO/3-92 .....id-TRTPPGLRAQQTMDMLNSDWP.I..GEVGV.....R....TLAAPAMVES--.-.--.VQRAME.ALWWD.RP.F.TI.DSIDI...T..AG....A....ATLHLI.T.SYGARQDI.RIHTGEDR--lv.............................
A0A132PM56_9MYCO/31-120 .....id-TKTPPGLRAKQTMDMLNSDWP.I..GPIGV.....R....TLAAPEAVDE--.-.--.VGTKMD.SIWWD.RP.F.RV.TSVDI...G..AG....Q....ATLHVL.T.SYNVAQDI.ELRTDDLGMV...............................
A0A164NX58_9NOCA/24-112 ...apps-----ATDQMNWFVGATAR-AP.I..SESEL.....A....EHLSPSFLSAVG.A.DG.FNASLT.HLGKL.--.-.TE.QRLAD...A..TP....T....GVQAFL.G.H-GAQTDMaSLAVDRSGLI...............................
A0A1R3XE50_9MICO/1-90 ......m-----LGEQAQWVLDSINGEVD.D..PASES.....S....GRLSPVLLEQIS.A.AD.LAAVFA.QLAPQ.GP.W.VP.TAVQD...A..GD....S....ALITIR.P.ASGDALDM.QIAVDADGLI...............................
A0A6N4W7N8_9MYCO/1-76 .......-------------MDMLNSDWP.I..GAPSV.....K....TLAAPDMVNS--.-.--.VATAMD.SLWWD.RP.Y.TL.AGVDI...G..AG....V....ATLHLL.S.SYGARQDI.EIRTGDD---tfv............................
A0A6L9S9Y0_9ACTN/67-160 ......f-PDTPAGQQARWVLEQLAAETG.P..DAQNA.....A....ERFSDVFLAEIP.A.DQ.VSATFD.GLREL.GP.F.TP.VEYSG...D..AR....Q....AMVELV.G.SGSSRYRM.SLGVDRDDAI...............................
A0A5C4WFA7_9ACTN/64-153 .......IPDTPAGRQLRWLLDALTR-AP.V..PDSEL.....A....GHFTATFLENIP.P.EQ.MNQVLV.AFKGL.--.-.RL.EQITK...S..QD....R....ELVALG.T.AGGAPYEI.SLSVDATGLI...............................
B5GLD6_STRCL/24-114 ......a-DDSPMGDAARWAMGLLTSSGL.P..RPEDV.....A....ARFIPTFAAA--.-.GN.FAETVR.EWRSK.GP.F.TV.RAYHP...V..AH....K....GWVVLS.A.PAGVRYIL.SLTLDSSGLI...............................
A0A895XQR4_9ACTN/48-137 .......IPQTPVGEKLQWYLDKLES-LP.L..EKEEA.....E....QHFAQTFLDQVP.V.AD.LNPIMS.DMRGT.--.-.IV.TDILD..dE..PS....R....LRAEAF.H.GTG-DFHI.IIEIDSDSKI...............................
A0A329QEW1_9ACTN/49-142 .......IPDDPLGSQVQWVLDQLAAGSG.P..DPETA.....A....ERFDDEFLNQVE.P.DE.VGPMFA.QLRAG.GP.Y.TP.TSFQS...D..GQ....V....ATLILA.G.TDDTEWQL.HVGIDDDERI...............................
Q9CBI7_MYCLE/51-140 .....id-TRTPPGVRAQQIIDMLNSDWP.I..GLVGV.....R....TFASHDMVEI--.-.--.VKTTLE.ELWWD.RP.F.TL.EGVDI...G..AS....V....ATLHLI.S.SYGAQQDI.RIHTDGNSWV...............................
A0A1Z4EPA5_9MYCO/26-115 .....id-TRTPPGLRAQQTMDMLNSDWP.I..GPVGV.....R....TLAAPDKVDP--.-.--.VETIME.ALWWD.RP.F.AL.DSVDI...S..AS....A....ATLHLT.S.SYGARQDI.RIHTDDDGRV...............................
A0A542YPH7_9MICO/94-192 ......l-PEGALGEQAQWVLDQLAPDAT.P.tTSEEA.....E....ERFSADFLDAVP.A.DQ.IEPVFA.QLRSA.EP.V.TL.VDVTE...Q..AG....TgdgsGSAVLR.V.TGTEPLVI.TISVDADDRI...............................
B0RFF5_CLAMS/3-96 .......LPSSPVGQQAQWLLDTVNADDA.V..PVQET.....G....ERLAQVMLDAAP.A.EE.LAGVLE.QVRGG.RP.W.TA.TAHEE...Q..GG....Q....SVTTIA.S.EGAGTFDM.QVAVDDAGLI...............................
A0A193LJP8_9GAMM/125-217 ......l-PNMPAPNQLTWILEQLAV-AS.T..SDQDI.....M....DHFSPAALASVS.V.AE.WQAFLN.SLRAV.VP.GgTV.QDI--...-..--....-....------.-.--------.----------itmtptqvrvlvgdagtpgsgqfmtlqtty.
A0A160DSP2_9GAMM/45-125 ......l-PPGPAADQLRWLIGELAAGET.T..SIAEI.....N....AHFDAGWLSQTP.A.AQ.TQAFIA.SVRAS.YPdA.VI.TDVIG..lT..PV....R....ATVVI-.-.--------.----------dspgs..........................
W9AYB5_MYCCO/53-142 .....is-TNTPPGVRAKQLMDMLNSDWP.I..GPVGV.....K....TLAAPAQVDD--.-.--.IGTTMD.MMWWD.RP.Y.TL.AGVDI...G..AG....A....ATLHVV.T.SYGARQDI.ELRTDDT---ttl............................
A0A378TF18_9MYCO/46-135 ....ist--GTPQGVRAQQIMDMLNSGWP.I..GPDGT.....R....TLADPDLVEY--.-.--.VWLTMD.SMWYD.RP.Y.TL.AGVDY...G..AG....T....AKLRLV.T.SYGGRQDI.EIRVDQDST-l..............................
A0A1H8QD37_9PSEU/6-96 ....aas---ATAGEQLDWLVAASTR-AP.L..PDNEI.....R....QRIAPSLVDG--.S.GG.PDGINA.ALAGV.GP.L.TV.HSILA..tR..RD....Q....AQAAVR.G.RAG-DYLL.TVHVDAAGLV...............................
A0A841DDB9_PLAVE/46-135 .......IPDSPAGRQLRWFLEASGR-AP.L..AASEI.....E....EHLSAEFLKHVT.V.DG.FNGFLK.QTAGL.--.-.KL.DTLTQ...V..TP....T....SLTGTA.T.LAGQKFDL.QLAVDADGRI...............................
A0A0T1WF29_9MYCO/37-126 .....ia-TSTPPGLRAKQTVDMLNSDWP.I..GVPGV.....S....TLAATPQVDD--.-.--.IAFVMD.KMWWD.RP.F.TV.SGIDY...G..AG....Q....ATLHLL.T.SYGVGQDI.ELRTNDAGMV...............................
A0A6N4VHT3_9MYCO/51-138 ......i--NTPQGLRAKQTMDMLNSDWP.I..GEVGI.....R....TLAAPDIVEH--.-.--.VGVTLD.RMWWD.RP.F.TV.TDVDI...G..AG....N....ATLDVV.T.SYGVGQTI.TLRTDDAGMV...............................
A0A1A1ZBA3_9MYCO/35-122 ......i--NTPQGLRAKQTIDMLNSEWP.I..GTVGV.....K....TMATPQQVNP--.-.--.ITSAMG.NLWLD.RP.I.TV.AGIDI...G..AG....Q....ATLHTV.T.SYGAAQDI.ALRTNPQGLV...............................
A0A7W7QV38_9ACTN/48-137 .......IPDTPAGKQLTWFLDALSR-VP.L..AESEL.....R....EHFAAGFLKEVP.A.DE.INKFAA.TLKGL.--.-.KL.ESVTA...T..GA....T....SLHGTA.K.LGDKDYVI.TLSVDGDGKI...............................
A0A1H8J442_9ACTN/52-141 ......v-PGTQAGRQLRWFLDAAAK-PP.V..ADADL.....T....AHLSADFLADVP.P.AK.LNELLG.QLAGL.--.-.RL.ERVTE...S..TP....A....ALTAQV.R.AGGQSLRL.ALGVDADGKI...............................
A0A7I7S4P1_9MYCO/38-127 .....id-TNTPQGLRAKQLVDMVNSDWP.I..GTVTV.....G....TLASPELIEP--.-.--.VAGAMD.RLWAD.RP.I.TV.TGIEV...G..AG....S....ATLHLL.T.SYQVAQDV.KLRTNDAGLV...............................
A0A1A3PHS8_9MYCO/51-139 .....dm--RTPAGLRAQQTLDMLNSDWP.I..GPVGV.....G....TLAAPKMATQ--.-.--.IQTMME.KLWWD.RP.F.TL.HGVDI...K..AG....A....ATLQLT.T.SYGAEQEI.RIHTNDDTL-v..............................
A0A1X0CTS3_9MYCO/32-118 .....ig---TPQGVRAQQVVDMLNSDWP.I..GTDSV.....K....TLAGPDQVDF--.-.--.VAGAMD.LLWWE.RP.Y.TV.ADIEY...G..AS....S....AELTLN.T.SYGGQQLI.SLRVNDDS--s..............................
A0A848K9T4_9NOCA/108-196 .......LPDTPAGTQLTWALQHGGT---.A..TDDEL.....R....QHFSADALAAIA.P.DK.LREVLQ.GGPDT.--.-.TI.VKVTK..sE..DT....S....LDAIVK.T.KDETQFRV.SITVDPT---shl............................
A0A7W8EFM0_9ACTN/47-136 .......IPATPAGQQLRWVLDAIGR-AP.V..PESEI.....K....EHIADSYLAAVP.P.AE.VNAFLQ.QLAGL.--.-.TL.NAVDS...S..RP....K....QIEVTA.T.LAGHKLTV.TLGVDDTGKI...............................
A0A438ME53_9ACTN/46-135 .......IPSTPAGNQLRWLLDAAAR-PP.I..SESEL.....A....QHFSAGFLKSIP.P.AQ.INQVLA.NFTGM.--.-.RL.ERLTK...S..QD....R....ALIARV.A.AGGTSYEV.ILSVDAAGLI...............................
A0A0N9XM93_MYCFO/55-143 ....dti---TPPGLRAKQTMDMLNSDWP.I..GPIGV.....R....TLAAPEKVDL--.-.--.VGTKMD.SIWWD.RP.F.KV.TSVDI...G..AA....Q....ATLHVL.T.SYNVAQDI.ELRTNDVGLV...............................
A0A1X1RA19_MYCFA/45-134 ....ist--GTPQGVRAQQIVDMLNSDWP.I..GTESI.....K....TLAGPDQVDF--.-.--.VTAAMD.QLWWE.RP.Y.TV.AGIQL...G..AG....S....AELQLA.T.GYGGRQNI.DIRTGSS---tlv............................
A0A5N0T666_9MICO/35-129 .......LPDTAAGRMAGWVLEVMNADAD.S..TVQQW.....E....GRLHPDFRAEVS.A.DE.VTELINtRIRPA.RP.L.VA.TAYRG...A..ER....E....AVITVE.G.RRGEPFDM.SVVVDAEDRI...............................
A0A1X2C947_9MYCO/51-140 .....id-PTTPPGIRAQQTLEMLNSDWP.I..GPVGV.....G....TLAAPGMVDP--.-.--.VETTME.RLWWD.RP.F.TL.DRVDL...S..AS....V....ATLHLT.S.SYGARQSI.RLHTDDDGRV...............................
A0A1B1NFI9_9MICO/66-162 ......i-PEEELLEQTEWVLGLLEEDAT.G.pAAEES.....A....RRFAPTFLEEVS.V.IQ.LGTIFA.GLRGS.AP.Y.TV.TSAAQsegV..GR....T....ATLTLH.A.ADQ-PLVM.TLSLDENDQI...............................
A0A1X2C350_9MYCO/51-140 .....id-TRTPPGLRAQQTMDMLNSDWP.I..GPVGV.....G....TLAAADQVDS--.-.--.VAKTME.ALWWD.RP.F.SL.DSVDI...G..AS....V....ATLHLI.S.SYGARQDI.RIHTDDGGWV...............................
V5XJA6_MYCNE/49-138 .....ie-TNTPQGLRAKQLLDMVNSDWP.I..GVVPV.....A....TLAAPQQVEF--.-.--.VAGAMD.RLWAD.RP.I.TV.TALSL...G..AG....E....ATLHVR.N.SYNVAQKI.EMRTGDGGLV...............................
A0A1X0H1X1_9MYCO/48-135 ......i--NTPQGLRAKQTLDMLNSEWP.I..GTVGV.....R....TLAAPEQVNG--.-.--.VTSAMG.NLWLD.RP.I.TA.TGIDY...R..AG....E....ATLHVV.T.SYGVAQDI.ELRTNDEGLV...............................
I4BQ48_MYCCN/52-139 ......i--NTPQGLRAKQTMDMLNSDWP.I..GEVGV.....R....TLAAPQVVEN--.-.--.VGVTLD.RIWWD.RP.F.TV.TKIDV...G..AG....N....ATLHVL.N.SYGVAQTI.SLRVDEAGMV...............................
A0A7I7MWS6_9MYCO/1-76 .......-------------MDMLNSDWP.I..GAVGV.....R....TLATPEKVDS--.-.--.VTTTMG.ALWWD.RP.F.TL.DGVDI...G..AS....V....ATLHLV.S.SFGARQDI.RIHTDDDGWV...............................
A0A1V9KL92_9ACTN/18-110 ......a-DDSPMGEAARWAVGLLTA-PD.L..AADDV.....T...vERFVPTFPPR-R.S.EG.FSVTLG.EWREK.GP.F.TV.LDYQP...I..AH....K....GWVTLG.G.PAGVRNTL.SLTLDSSGLI...............................
A0A5D0QL59_9ACTN/32-122 .......VPDSPVGKQLQWYLDAVNR-TP.I..PENEL.....G....EHLSEAFLKEIP.A.DK.FNGIAK.DLAGL.--.-.KL.DELSS...T..KP....N....ELAGVT.SiPAGQKYDT.KISVGDDGKI...............................
A0A1E3SEG7_MYCIE/47-136 .....id-TNTPPGLRAQQTLDMLNSDWP.I..GPVGV.....A....TLAVGDKVDS--.-.--.VETTME.ALWWD.RP.F.TF.DGVDI...G..AS....V....ATLHLV.S.SYGARHDI.RIHTDDTGLV...............................
A0A1A3N106_MYCAS/35-124 .....id-TSTPPGLRAQQTMDMLNSDWP.I..GPVGV.....R....TLAAADQVEA--.-.--.VEATME.GLWWD.RP.F.TL.SGIYI...G..AN....V....ATLQLV.S.SYGARQDI.RIHTSDLGEV...............................
A0A6G7XHD9_9MICO/48-145 .......LPDTSTGKLADWVITQMNGTSP.T..DGAEL.....K....TRMDPELLKGIK.E.AE.LAKILD.ERQAS.RN.W.VP.TKVKE...T..T-....-....------.-.--------.----------iddmnviyvrlqsdssdavtvlqisqsrksk
A0A239V4Q0_9MICO/41-132 ......y-PNDTIGQAMQWFVGQMST--D.K..TDSNL.....A....QRLSSEFTKHIS.P.QQ.LLVFFG.ELRPQ.GP.W.IT.ENTTT...N..GN....N....GTATLM.N.KYGQRFTL.TMHVDDNGKI...............................
A1TG24_MYCVP/52-139 ......i--NTPQGLRAKQTMDMLNSDWP.I..GEVGV.....R....TLAAPEAVEH--.-.--.VGVTLD.RIWWD.RP.F.TV.TNVDV...G..AG....H....AKLDVL.T.SYGVAQTI.ELRTDEAGMV...............................
A0A1X0DQ25_MYCHE/51-140 .....id-TRTPPGLRAQQTMDMLNSDWP.I..GPVGI.....S....TLAAPDKVSS--.-.--.VENTME.ELWWD.RP.F.AL.DGIDI...G..AS....A....ATLRLV.S.SYGARQVI.RIHTDDDGRV...............................
A0A5D0QEW8_9ACTN/41-130 .......VPGTPAGRQLAWLLDASTR-AP.I..AEDEL.....A....AHFAADFLKAIP.P.AQ.LNQVLA.TFRDL.--.-.KL.ESVRT..sQ..DR....S....LVARVL.V.G-ASAFDV.ALSVDAAGL-m..............................
A0A1R4FU27_9ACTO/65-160 ltdpelv-------TQVQWLLDQLAAPAA.P..DESAI.....E....ERFAPDMLEAAP.P.EE.LARVFD.QLRPG.GP.Y.TV.TAVSE..gTdpAP....S....ASVRLS.S.ETA-PTIM.SVSIDDAGLI...............................
A0A2R5H4K5_9MYCO/34-123 .....id-TRTPPGLRAQQTVDMLNSDWP.I..GPVGV.....R....TLAAPDKVDS--.-.--.VETTME.ELWWD.RP.F.AL.DGVDI...S..AS....V....ATLHLT.S.SYGARQDI.RIHTDDVGRV...............................
A0A0W7WCP4_9MICO/57-152 .......VPQTTAGLQIQWMLDLLNADAD.I..APQDF.....D....GKFTKSFTEEAP.S.AT.VAEQMNaGVRPD.KP.F.VV.TDYQD..vS..DV....L....GAARIT.G.ASGQALSL.EMRVEEDGTI...............................
X8B813_MYCAV/33-122 .....id-TRTPPGIRAQQTLDMLNSDWP.I..GPVGV.....R....TLAAADKVES--.-.--.VQTTLE.ALWWD.RP.F.TL.NGVDI...G..AS....V....ATLHLT.S.SYGARQDI.RIHTDDGGWV...............................
A0A5N5VB55_MYCPH/23-110 .....al--NTPQGVRAKQTMDMLNSDWP.I..GTQSV.....S....TLAVPKKVDE--.-.--.VTAILD.SIWWD.RP.F.TV.TDVEI...G..AG....T....ATLGVL.T.SYNVAQEI.SLRVDP----tda............................
A0A8J3RMW6_9ACTN/46-135 .......IPDSPAGRQLRWFLGAPDR-AP.L..AESEV.....A....EHFNAAYLKQMT.V.EG.FNTFLS.QVKGL.--.-.KL.EKLTK...V..GR....T....ALTGTG.T.IGGQEFTI.QIAVDGQGKI...............................
A0A4P8KP64_9MICO/43-137 .......IADTPVGAKTSWIVDVLGADED.T..TAAEW.....E....PHLDAAFTAEVS.A.AE.VADLLNtQIRPA.AP.F.IV.TAYRG...D..ER....S....AVTTIK.G.TIGEAFDM.TVALNDDDKI...............................
A0A346Y573_9ACTN/60-152 ..atgas-----PESHLAWFVSEAAQ-PD.I..DAAEY.....E....DRFAQVFRDQVP.L.EQ.FTAILE.DLSTL.AP.Y.TT.GEVEV...V..GP....Q....LVGQLT.G.SDGTGLIV.TLSVDADGR-m..............................
A0A4R8R0X9_9MYCO/45-133 .....dt--STPPGLRSQQLIDMLNSNWP.I..GKQGV.....A....TLATANKVDD--.-.--.YTEIMT.KLWVD.RP.Y.KV.SSVDL...G..AN....S....STVHLI.A.PYGANVDI.GLRTNYKGD-v..............................
A0A7W5VE85_9ACTN/46-135 .......IPDTPAGRQLSWLMSAVPD-AP.I..PEQQL.....T....EHFSALMLSALP.P.AE.LNAVLV.GTKDL.--.-.RL.IKILY..aV..DT....A....ITAEVT.T.-GGRTLWM.ELTVDAEGKI...............................
D1BK86_SANKS/39-132 .......MPDGPAGEQAVWVLSQLDPEVT.V..DADEV.....A....ERVAPEALAEMS.A.EE.LAGALT.SVGAT.GP.W.TA.VAVRG...E..GS....A....VAVTIT.D.TTGTFLEL.QVATDDAGQI...............................
A0A2W2EB24_9ACTN/81-169 .......IPDTPVGRQLTWLLDAVGR-AP.L..PESEL.....T....AHFAADFLASVP.A.AQ.LNEVLV.QFAGM.--.-.RL.EQLQV...Q..QN....A....LVARVT.A.-AGTPFTV.QMTVDGAGLI...............................
A0A1B7LX78_9MICC/49-145 ......f-PDSEVAQTSEWVVEEINGVRA.I..NKQDW.....Y....PRVSPELSEDIP.V.DS.LVGTLNsQLRPS.LP.F.VP.SDYEE..pE..PN....Y....GITRLTpD.LTAQPVDL.HIQVDNTGLI...............................
A0A0A0BT01_9CELL/94-186 .......LPDDDAGHQAAWVVERLADADD.P..AVVDV.....E....ARFTDGFLAEVP.A.AR.LVEVLA.SIRAA.GP.W.TP.VSVDG...G..AQ....G....LVVRLA.G.PQD-DLDM.QLAVDAEGRI...............................
A0A2P8DJZ0_9ACTN/104-197 .......LPHSAVGRQARWVLDQLALETG.P..TAAEA.....R....RRFGTRFLDEVP.P.AE.VNTVFD.ELRPA.GP.W.SP.VDVDA...V..GG....D....AVVRLH.D.GSGEPWRM.VISLGGDGTI...............................
A0A0S9DWB3_9MICO/57-149 .......LPDTPVGEKAQWVLDAVNSDAE.T..TEAEV.....E....ANVGAEMLEQVP.A.GQ.LVTVFA.QMGDA.KP.W.IA.AEVSE...E..TN....G....LLVLLH.S.DAA-ELQM.SISIDEQQLI...............................
A0A498R257_9MYCO/53-142 .....id-TRTPPGLRAQQSVDMLNSDWP.I..GPVGV.....G....TLATPGQVGS--.-.--.VAHTME.ELWWD.RP.F.TV.EGVAI...G..AS....V....ATLHLI.S.SYGARQDI.RIHTDDQGQV...............................
B2HJ33_MYCMM/53-141 ....dtv---TPPGLRAQQTMDMLNSDWP.I..GPAGV.....A....TLAAPSKVDS--.-.--.VEATME.GLWWD.RP.F.AL.DSVDI...S..AS....V....ATLHLT.S.SYGARQDI.RLHTDDGGWV...............................
A0A1B7LWH1_9MICC/52-147 .....ia-TDTPAGEESQRIVDLLNAEED.T..TAEDW.....E....ASLHPSFTEDVS.V.EE.LVELFNqNLRPA.QP.F.TV.TNYEG...G..DR....Q....AVTTLT.S.PISDPLDM.TVTLDTDALI...............................
A0A7I7SIL3_9MYCO/5-93 .....nt--GTPPGLRAQQTLDMLNSDWP.I..GPQSV.....A....TLATPKKVDE--.-.--.VVERLD.SLWWD.RP.Y.TV.DDVEV...R..AS....S....ATLHLR.A.SYGARQDV.ELRVGDDGLV...............................
F6EGX8_HOYSD/63-157 .....ip-ADTPAGSHSAHILDLINGDDP.I..SPGAV.....R....EWTDPSVAAALG.P.DG.LAAPLE.QLRTT.GP.Y.EF.VDYSG...T..NA....A....ATVTLK.T.RTGLPVEL.RIYVSADNTV...............................
A0A4U3MQ40_9ACTN/42-131 .......IPDSPVGRKLSWYLGALAA-LP.I..PAEQI.....D....ENFAPSFVKQVP.A.EQ.INEVSN.QLKGL.--.-.RV.VEIQR...A..TE....T....DLVALV.Q.SGENQAKL.SMAVDPTGKI...............................
A0A429B4E2_9ACTN/48-137 .......IPDTPAGRQLTWLLDAVNR-LP.V..GDAEL.....A....GHFAPTFLEHIP.P.AQ.LNQALA.GFGGM.--.-.RL.DRLDQ..aQ..ER....S....LSATVA.A.-GGKAFTL.ALGVDGTGKV...............................
A0A0W8IA89_9MICO/69-162 .daellg--------AVEWVLELLEEDAE.G.pTVREA.....T....ERVAPDLLEQVS.P.VE.LGLVLG.QVRSA.GP.Y.VV.TAVVP..sS..GV....G....RAATLS.L.AAQDPLLM.TVGVDEQGRI...............................
A0A7W9MIM0_9ACTN/47-136 .......IPDSPAGRQLRWFLEALSR-TP.I..AESEL.....R....EHFNADALASLT.V.EG.FNDFAK.QVAGY.--.-.QL.EKLTT...V..TP....T....ALEGTG.T.LGGQRFTL.QLGVDGEGKI...............................
A0A1Q4HEC4_9MYCO/42-131 .....id-TNTPQGLRAKQLLDMVNSDWP.I..GVVPV.....A....TLAVPQQVEW--.-.--.VAGAMD.RLWAD.RP.I.TV.TAMSL...G..AG....Q....ATLRVR.N.SYSVEQTI.KLRTGDTGLV...............................
A0A2S8LIS4_9MYCO/74-163 .....id-TNTPQGLRAKQIMDMLNSDWP.I..GPNGI.....R....TLADPEIMDD--.-.--.VGVTMD.KIWWD.RP.F.TL.TDLDI...G..AG....H....ATLHTL.T.SYAVPQTI.ELRTNEAGLV...............................
A0A852SIW3_9MICO/55-151 .......LPDTAVGEHAAWVIESIST-EP.T..EPDQI.....EgqatERLSPSVASQLT.P.AQ.LAEVFT.GLRAS.GP.W.VP.TSVQS...A..EG....Q....ALITIV.D.RDGQKLDL.QLSLDGEELI...............................
A0A0D1JMD8_9MYCO/31-119 .....dm--TTPQGMRSRQTMDMLNSDWS.I..EPAGV.....K....TLAAPDQVDD--.-.--.ITYRMK.WIWWD.RP.F.KL.TGIDI...G..AG....H....STLHVT.N.SYGVNQDI.ELHVDSKGTV...............................
A0A516G893_9MICO/103-199 ..dgelr-------EQTQWLLERLTEGATgP..SEEEA.....A....ERFSTDFLEAVP.A.DQ.IEPVLT.QFRGG.PA.L.TL.SAVGE...V..QErgdgA....YGVELT.L.TGEQPLRL.SLGVDADGLI...............................
A0A1X1QYJ8_MYCBE/50-139 .....id-TRTPPGLRAQQTVDMLNSDWP.I..GPVGV.....G....TLAAPDKVDS--.-.--.VDNTME.RLWWD.RP.F.TL.SGVDI...G..AS....V....ATLHLI.S.SYGAQQDI.RIHTDDDGRV...............................
X8C7M2_MYCXE/33-120 ......i--RTPPGMRAQQTVDMLNSQWP.I..GPVGV.....R....TLAAPQMVEP--.-.--.VKTTME.GLWWD.RP.F.TV.GGVDI...S..AG....A....ATLHLI.T.SYGAHQDI.KIHTNDDTL-v..............................
A0A251XNX8_CLAMM/54-148 .....il-PGSAVGQQAQWLLDTVNAEEA.V..PVQGT.....G....ERLAQVMLDAAS.A.ED.LAAVLE.QVRAG.RP.W.TA.TAHEE...Q..GG....Q....SVTTIA.S.EAGGTFDM.TVAVDDAGLI...............................
A0A554UWR9_9ACTN/34-127 .......LPATPAGERAARVLQIIDSDQP.P..SVPET.....V....AMSDPRLTAALW.P.QT.LAGALT.LWQLS.GP.F.ST.VSSES...G..PD....Q....ETVRLR.T.NRGLPADL.TVHVDPVGLI...............................
I2A818_9MYCO/51-140 .....id-TRTPPGIRAQQTLDMLNSDWP.I..GPVGV.....G....TLAAADKVES--.-.--.VQTTME.ALWWD.RP.F.TL.DGVDI...G..AS....V....ATLHLT.S.SYGARQDI.RIHTDDGGWV...............................
A0A7G1I937_MYCKA/25-114 .....id-TRTPPGLRAQQTVDMLNSDWP.I..GPVGV.....G....TLATPGQIGS--.-.--.VEHTMA.ELWWD.RP.F.TV.EGVAI...G..AS....V....ATLHLV.S.SYGARQDI.RIHTDDQGQV...............................
A0A3S4S512_MYCCI/49-138 ....ist--GTPQGVRAQQVMDMLNSDWP.I..GPVGV.....E....TLAAPDQVDA--.-.--.VVTTMD.GLWWD.RP.Y.TL.SGIEY...G..AG....S....ATLRLL.T.SYGARQDI.ELDTDDAGMV...............................
A0A8J8HA20_9ACTN/30-119 .......IPDSAVGKQLQWYLDAVNR-TP.L..PESEL.....A....EHLGKDFIQDVP.P.EE.FNEIAG.TLAGL.--.-.KV.DELTD...V..KP....D....ALVARV.S.VPEQAYKV.EISVDDKGKI...............................
O06155_MYCTU/49-138 .....id-TRTPPGLRAQQTMDMLNSDWP.I..GEIGV.....G....TLAAPGQVDT--.-.--.VKTTME.ALWWD.RP.F.AL.AGVDI...G..AS....V....AALHLI.S.SYGAQQDI.RIHTDDDGWV...............................
X8FM64_MYCUL/1-42 ......m---TPPGLRAQQTMDMLNSDWP.I..GPAGV.....A....TLAAPSKVDSVE.A.--.------.-----.--.-.--.-----...-..--....-....------.-.--------.----------pw.............................
D2ARL9_STRRD/46-135 .......IPDSPAGRQLSWYLDAVPR-VP.I..AESEL.....K....EHFSTDFLTSIP.A.DD.LNAFTG.QLKGM.--.-.TL.EKLTT...V..KP....D....LLVGQV.T.IAGQGFVL.TISVDGDGKI...............................
A0A852V721_9ACTN/76-165 .......IPDSPAGRQLRWFLDATTR-AP.L..TADEL.....G....QHVNADYLKQLT.V.DG.LNRFLK.GLAGI.--.-.RL.EELTR...T..DP....V....LLTGTT.V.LAGQRFDV.RLGVDASEKI...............................
A0A2A9D409_9MICO/65-158 ......v-PADDLGRQVTWVTEALDPDTP.A..STDDV.....I....AHVSEATLAQIS.A.DD.LRLTLT.RLGLT.GP.W.QV.VGYEA...D..QD....G....ALATIR.D.TAGTELEL.TLTLAQDGLI...............................
A0A438MJG7_9ACTN/32-122 .......IPDSPAGKQLRWYMDAVNR-AP.L..PESEL.....K....EHLGQDFLKGVP.P.EK.FNEIAQ.SLAGL.--.-.KL.DELSS...T..KP....T....ELTGLT.SiPLGQAYDM.KISVGDDGKI...............................
A0A0D0I007_9MICO/54-149 .......IPQTPAGEAMRWVIDVFNSTED.P..AAAEI.....E....EMFADDFLELVP.V.PD.FLAQTNaVIRPA.AP.F.EV.ASYDA..pD..ER....T....GVAIIE.G.TVGGQLQV.QLILDDDGEI...............................
A0A2P8GRR3_9MICO/4-97 .......IPDTVVGEHITWTLDALNGKIE.P..TAADV.....E....ERLDADMLAAVS.G.DQ.IVDIIG.QLGAG.KP.W.TP.TAYEG...T..DT....Q....ASATIV.S.ESQGSLDV.QASVDGDGL-l..............................
I0RMF6_MYCXE/1-82 ......m--------RAQQTVDMLNSQWP.I..GAVGV.....R....TLAAPEMVEP--.-.--.VKTTME.GLWWD.RP.F.KV.GGVDI...S..AG....A....ATLHLI.T.SYGARQDI.KIHTNDDTL-v..............................
A0A3N6GD36_9ACTN/24-115 ......g-DDTPLGVRTRWAAGLLTA-PG.L..PDEDL.....T....GHFVPVFLAR-H.P.RG.FVATLE.QWREH.GP.F.TV.VDYQP...V..AH....K....SWVTLA.G.PTGVRSTL.SLTLDSSGLI...............................
A0A7I7XMY9_9MYCO/48-137 .....ie-TNTPQGLRAKQTVDMLNSDWP.I..GPDNV.....A....TLAAPKQVND--.-.--.VAFVMD.RMWWD.RP.F.TV.TGIDV...G..AG....S....ADLHLL.T.SYGVGQDV.ELRTNDEGMV...............................
D2AXP4_STRRD/32-122 .......IPDSPVGKQLRWYLDAVNR-TP.I..AESEL.....N....EHLSQDFLKEIP.P.QK.FNEIAQ.GLKGL.--.-.TV.DELSK...T..EP....A....ALTGLA.SiPLGQKYDT.KISVGTDGKI...............................
A0A2V1K806_9ACTO/67-161 ......f-PSTEAGKAMEWIHTVLEQDAD.V..AEGDV.....E....GRFSQEFTAEVP.P.TE.LVSLFNeNLRPA.AP.F.EV.TDYAG...D..EL....T....SSATFT.G.SEGDPFVV.QIAVDADGTI...............................
A0A3M2JEV3_9CELL/108-203 .......LPDTPVGDTARWVLRVLAASEA.P..PVAEL.....E....RRFAPSFLEQIP.V.SD.LAAVLV.QVQEQ.GS.Y.TP.VAVAP..pD..AT...tA....LEMTLA.T.EGGEFVAV.QIGLDADGLV...............................
A0A2G5P7G2_9MYCO/29-118 .....is-TTTPQGVRAQQILDMLNSDWP.I..SQESV.....K....TLAGPEQVDF--.-.--.VTTAMD.QLWWE.RP.Y.RV.AEVDY...G..AA....T....AELQLA.T.SYGGRQTI.DIRTA-----pstlv..........................
A0A7X5TT83_9MICO/57-155 .......LPDTMVGNQAQWVIDTMNAAPA.P..EVSEAevkatE....ERFAQLMLDEVS.A.AD.LSALFN.GLRDQ.RT.W.VP.TAVKE...F..DD....S....MIVTLH.G.TSGEPVDM.SIAVDSVGKI...............................
A0A1G8V0T2_9ACTN/46-135 .......IPDTPAGRQLTWVLDAVTR-AP.V..PESEL.....R....EHFAADFLASVP.P.AQ.LNQFLA.SVADM.--.-.RL.ERLSQ...S..SQ....N....ALVAEV.T.TLGEPYTV.RLGVDGDGLI...............................
A0A0M2K596_9MYCO/23-110 ......i--NTPQGLRAKQTMDMLNSDWP.I..GENGI.....R....TLAAPQVVEA--.-.--.VGVTMD.RMWWD.RP.F.TV.TEVDV...G..AG....N....ATLHVL.T.SYGVSQTI.ELRTDDAGMV...............................
A0A4Z1E6G3_9MICO/67-160 .......IPATPVGEQIAWTIAALAPGAT.L..DPADA.....E....SRLSPPALEQLD.G.AA.LAQTFA.GIAAT.GP.W.EP.ISYEG...E..DY....S....AIAQLR.D.AGGQRLDL.TVVVNAEGLV...............................
A0A5J6V8A4_9MICO/93-187 isdedll-------EQTRWALGLLEEETG.V.vSAGEF.....A....ERFDQAFQDQLS.A.FE.LSVGIG.PLRLS.GP.Y.TV.THAAV..gA..GR....V....ASLSLH.S.ER-RPLIL.SIGLDDEGRI...............................
A0A557XZ17_9MYCO/51-140 .....id-TRTPPGLRAQQTLDMLDSDWP.I..GPVGV.....R....TLAAPDDVKP--.-.--.VEATME.QLWWD.RP.F.AL.DGVDI...S..AS....V....ATLHLT.S.SYGARQDI.RIHTDEAGRV...............................
A0A132TAE9_9MYCO/23-110 ......i--NTPQGLRAKQTMDMLNSDWP.I..GEVGI.....R....TLAAPPIVEH--.-.--.VGVTLD.RMWWD.RP.F.TV.TDVSV...G..AG....N....AKLDVL.T.SYGVAQTI.ELRTDEAGMV...............................
A0A1X1SYJ5_9MYCO/52-140 ....dkg---TPPGLRAQQTMDMLNSDWP.I..GPVGV.....G....TLAIPDKVES--.-.--.VVKTME.GLWWD.RP.F.TL.DHVDI...S..AS....V....ATLHLI.S.SYGARQDI.RIHTDDGGWV...............................
A0A7W9GCV9_9ACTN/44-133 .......IPDTPAGRQLRWLLDAATR-LP.I..PESEL.....K....QHFSAEFLQSVP.A.DQ.LNQTLT.AFKGM.--.-.RL.QELTR...S..ES....A....LIVAKV.E.AAGTLLDL.SLTTDGAGLV...............................
A0A1V0AGH8_9ACTN/43-132 .......IPGTPAGRQLGWLLDAATR-AP.V..AESEL.....S....GHFTAAFLKSVP.P.AQ.INQTLA.GLKGI.--.-.RL.ERVVS...S..KN....G....YLVAQA.A.VGAESVNI.VITVDAAGL-l..............................
A0A8J3T1C8_9ACTN/46-135 .......IPDSPAGRQLRWFLDAPNR-AP.L..AESEL.....A....GHVNADYLKQLT.V.AG.FNDFLA.QAKGL.--.-.TL.EKLTQ...V..TP....T....ALAGTG.R.LGGQEFVI.RIAVDGNGKI...............................
A0A1E8Q5P6_9MYCO/38-127 .....id-TNTPQGLRAKQLLDMVNSDWP.I..GTVTV.....G....TLAAPEIIEP--.-.--.VARDMD.RLWAD.RP.I.TV.TGIDV...G..AG....M....ARLHLR.T.SYAIDQEV.ELRTDDAGLV...............................
A0A1X2LUJ8_9MYCO/56-145 .....id-TRTPPGVRAQQTMDMLNSDWP.I..GPLGV.....R....TLAAPDLVDK--.-.--.VTTTME.ELWWD.RP.F.AF.DGVDI...G..AS....V....ATLHLI.S.SYGGHQDI.RIHTDDGGWV...............................
X7XRV6_MYCKA/1-46 .......----------------------.-..-----.....-....------------.-.--.----MA.ELWWD.RP.F.TV.EGVAI...G..AS....V....ATLHLV.S.SYGARQDI.RIHTDDQGQV...............................
A0A8J4A0R9_9ACTN/57-147 ......p-SDTTAGQQFAWLLDASGR-PP.V..AESEL.....R....QHLSVTFLDAAGgP.DG.VNAFLA.SVGRL.--.-.TL.REVLR..sD..AS....R....IEAVTV.G.AAG-TFVT.TLAVDAAGLV...............................
A0A1H6E5Q7_9ACTN/42-131 .......IPGTPAGGQLRWLLDAAPR-AP.I..PASEL.....G....EHFTADFLKNIP.A.DQ.LNQVLA.VFKDM.--.-.KL.VRLTQ..qQ..DR....S....LVARIA.V.GTL-PYDL.SLTVDGTGRI...............................
G9PGL4_9ACTO/92-185 .......MPTTPAGVAASWLLYSISNSKS.I..TQAQI.....R....SHFSQSLLKQTS.S.SN.LYNSLT.KLRAA.GP.Y.TM.LGYED...S..GN....R....LLIGVQ.D.SNGRQISI.DLVADSRSQI...............................
A0A0Q2QHU4_MYCGO/51-140 .....id-TSTPPGLRAQQTMDMLNSEWP.I..GPDGV.....R....TLATADKVES--.-.--.VEASME.SLWWD.RP.F.TL.DSVFI...G..AN....V....ATLQLI.S.SYGARQDI.RIHTGDTGEV...............................
A0A0P0ED64_9MICO/42-136 .......IPATPVGEATQWILGEMNAEDD.T..DPADW.....A....SRLHEDFTSQVS.A.EE.VAELINtQIRPA.RP.L.VA.TAYEG...T..ER....E....AVTRVE.G.SLGAPFDL.SVVVDGENLI...............................
A0A3N6D0W8_9ACTN/22-113 .....dg---TLLGHRTRWAVELLTAPEA.P..RDEDL.....S....AHFVPVFLAR-H.P.QG.FAATLE.QWRAL.GP.F.TV.TDYQP...V..AH....K....AWVTLQ.G.PSGARSTL.SLTLDSTGPI...............................
A0A1H1A199_9ACTN/55-144 .......IPDTPVGEQLRWYLGVVER-GA.I..SQQEY.....E....AHFAGEFLRKVP.L.DQ.FNTINR.GLAGM.--.-.RL.TGLRA...T..GR....N....GLEGTV.V.VGGQTFTL.RISVNDAGEI...............................
A0A0D0H7I1_9MICO/40-135 .......IPRSPVGSQVRWVHEMINADAD.P..SAGDI.....A....ARLHEEFLAEVP.A.EE.IVQLFAaSIRPA.RP.F.IA.TSYEE..rD..ER....T....ARAVFA.G.AVGEPFAL.DLAVDADGMI...............................
A0A4Q2M200_9MICO/34-127 .......IPSTPVGEQATWVVESLSSEHA.I..ETVDV.....D....GRFTEEMIAEVP.L.DQ.LALVLD.RFRET.RP.W.VA.TAYDG...D..ET....Q....AVVRLE.S.AKSTPLQM.TIAVDDAGTI...............................
A0A1X1TIK8_9MYCO/50-139 .....ig-TTTPQGLRAKQTMDMVNSDWP.I..GDVNV.....R....TMAVEAEVDG--.-.--.IIDAMG.NLWWD.RP.I.TV.TGVDI...R..AG....T....ATLRVE.T.PYGAEQDI.DLRTDDNGLV...............................
A0A3B0BA12_9MICO/31-125 ....ide--STAVGERTSWVVEILNDESD.T..TGSQW.....E....SVLDESFLEQMS.A.DE.MAALINeDLRPE.GP.F.EI.VRFEA...A..GP....D....AVTTLQ.G.AEE-EISL.SISTTDNGDI...............................
A0A1A0P978_9MYCO/32-121 .....id-TNTPQGLRAKQIMDMLNSDWP.I..GPNGI.....R....TLAAPEIMDD--.-.--.VGVTMD.KIWWD.RP.F.TL.TDLDI...G..AG....H....ATLHVL.T.SYQVPQTI.ELRTNDAGLV...............................
A0A7X8TKS2_9MICC/76-169 ......f-PGTLSGETAEYIVQILNAEED.S..TAEDW.....E....NRLSETFRSEYD.E.TE.LAEVINtGLRPA.AP.F.TP.TDHSD...T..GD....A....SVTHLE.S.EDA-EVEL.HIQLDEDELI...............................
A0A318ADW9_9MICC/84-180 ......f-PDNQLGDTGRWILNQINGNRA.I..DRSDW.....Y....DRVAPELTEKIP.V.DS.LVGTLNaELRPQ.KP.Y.VM.THYEQ..tD..QA....S....AMMTLTpD.ISAQPLDL.HFSIDEAGR-l..............................
K5BAD7_MYCHD/10-98 .....pi--NTPQGLRARQTMDMLNSDWP.I..GHVGV.....A....TLAAPDKVEE--.-.--.ITGELE.RIWWD.RP.F.TV.QSIEI...G..AG....R....ATLDVE.T.SYGVEQRI.TLATDDEGRV...............................
A0A7I7Z1D9_9MYCO/32-121 .....id-TRTPPGLRAQQTLDMLNSDWP.I..GPVGV.....G....TLAAPEQVDS--.-.--.VQTTME.SLWWD.RP.F.TL.AGVDI...S..AS....V....ATLHLV.S.SYGARQDI.RIHTDDQGRV...............................
A0A1E3RT17_9MYCO/22-109 ......i--NTPQGLRAKQTMDMLNSDWP.I..GEVGV.....R....TLAAPDEVDD--.-.--.IAVQLD.KIWWD.RP.F.TV.ANVDI...G..AG....Q....ATLDVV.T.SYGVEQEI.TLRTDDAGLV...............................
A0A0D0INK9_9MICO/59-154 .......LPQTTAGIEIQWMVDLLNADSE.I..TAQDL.....A....GRFTKSFTEEAP.L.DT.VAEQMNaGVRPG.KP.F.VV.TGYED..vS..DV....L....GAARIT.G.ASGDSLSL.EMRVEEDGTI...............................
A0A5S4GGQ0_9ACTN/92-181 .......IPGTPAGAQLRWLLDALSR-PP.V..AEREI.....S....AHFTADFLKSVP.A.TQ.VNQVFA.TFKGL.--.-.RL.EQVLT...S..QN....T....SLIALG.T.AGGTAFEV.LVSVDGTGL-m..............................
C7N0A8_SACVD/15-107 ....arr---PLVESRMRWAVEMLAEPGP.G..LAEDP.....R....DHFVAAFVDK-H.G.DG.LSALLD.SWRAQ.GP.F.TV.ESYTP...V..AH....K....GWATLI.G.PTGDRFTL.SIVIDSSGLI...............................
A0A3N2D8K0_9MICO/70-163 .......VPDTAVGREVSWVLGAIDPATP.V..TAEDA.....A....AHLGEAASAAIS.G.EE.LVVAFA.QVAAS.GP.W.RV.VSYTG...T..ET....E....AVATIR.S.PADDELDL.TVTLDEAGLV...............................
A0A5S9MVF4_MYCVN/36-123 ......i--NTPQGLRAKQTMDMLNSDWP.I..GENGV.....R....TLAAPEAVEH--.-.--.VGVTLD.RIWWD.RP.F.TV.TNVDI...G..AG....S....ATLNVL.T.SYGVAQTI.ELHTDDAGMV...............................
A0A849BNB9_9ACTN/50-143 .......LPGTPVGEAAGWVLDQLAAGAG.P..TPEEA.....R....QRFSPGFLDQLG.A.TP.VAEVFD.GLRAL.GP.W.TP.TAFDG...S..ET....E....ALLSLA.T.GSGTAYRM.QVVVDADGVI...............................
Q743X5_MYCPA/25-114 .....id-TRTPPGIRAQQTLDMLNSDWP.I..GPVGV.....R....TLAAADKVES--.-.--.VQTTLE.ALWWD.RP.F.TL.NGVDI...G..AS....V....ATLHLT.S.SYGARQDI.RIHTDDGGWV...............................
A0A7I7SN54_9MYCO/40-127 ......l--NTPTAVRAKQVMDMLNSDWP.I..GPDNV.....K....TLATTDMVEP--.-.--.VAHSMD.SLWWD.RP.F.TL.AGADI...G..AN....V....ATLHLL.T.SYGARQDI.DLRIGDD---tfv............................
A0A7J0C5B4_9ACTN/23-113 dsalagp---------CRWAMELLTAPEL.P..SEAEM.....A....PSLVPGFLDK-Y.P.RG.FTATLE.EWRAL.GP.F.SV.TTYQP...V..AH....K....GWLVLT.D.PSGRDFSL.TVIIDSTGLV...............................
A0A1A2G1E5_9MYCO/51-140 .....id-TRTPPGIRAQQTLDMLNSDWP.I..GPVGV.....G....TLAAPDQVDS--.-.--.VETTME.GLWWD.RP.F.TL.DGVDI...G..AS....V....ATLHLI.S.SYGARQNI.RIHTDDDGRV...............................
A0A0Q9D6S3_9CELL/30-126 ......l-PGGTVGKAAAWVLEVLNADAS.P..DAATL.....D....RRFARTFLDQVP.A.AQ.LVPVLD.QLRAD.RE.W.VP.VSVDVvdaG..EK....Q....AALTIV.G.ASGQFFTM.QIGVDADSRI...............................
A0A100VXA7_9MYCO/38-127 .....id-TNTPPGLRAKQTMDMLNSDWP.I..GPVGV.....R....TLASPEKVDD--.-.--.VGTKMD.RIWWD.RP.F.RV.SSVDI...G..AG....Q....ATLHVL.T.SYNVAQDI.ELRTNDAGLV...............................
A0A1A3C7D3_9MYCO/50-137 ......i--NTPQGLRAKQTMDMLNSDWP.I..GPVGV.....R....TLAVPDKVDD--.-.--.IAFRLD.RIWWD.RP.F.TV.TDVQI...G..AG....Q....ARIGVL.T.SYNVAQEI.DLRTDDAGMV...............................
A0A2T0MLS2_9ACTN/49-138 .......IPGTPAGKQLSWLFEAVPR-AP.I..ADDEL.....A....GHFTADFLKAVP.P.AQ.INQIFA.DVKGM.--.-.RL.ERIVG..sD..DS....Q....LVARVV.A.-GGTPFEI.VIVVDGAGL-m..............................
A0A7W8D527_9GAMM/60-149 ......l-PSNPTTDQLAWLMDELAAGET.T..TAEEV.....N....AHFSAGWLSQIP.V.AN.TQAFLQ.SLRTT.FP.D.AViDDVVT..vT..SI....R....VVVVIR.A.PA------.----------ddrlgylqig.....................
A0A1R1IAI3_9ACTN/52-143 .......LPDTPVGEAAQWVLDRLAADAG.P..TAEEA.....E....ERLGDEFLGQVP.A.DQ.VGQVFA.QLREE.GP.F.TL.VSWDG...T..DT....Q....GTAELD.S.PAT-PVLM.MIAL------kdgki..........................
U2YKT1_9MICO/56-148 .......IPGTPVGDQVRWVMDEINADAA.T..DIEDI.....E....THFDAAALEQLP.P.AQ.LQDVFA.QMQAA.AP.W.TA.VGYDG...V..ET....Q....ARVTIE.S.AQV-TYDM.SISVTPDARI...............................
A0A0D5AIM5_9NOCA/31-124 .....dt--STPVGALNERILRWINAEEA.P..DPAEV.....D....AVTGPELAEAVA.P.LGgLAGPLE.QLRAG.AP.N.VA.MGFEA...G..PD....S....GVLRFT.T.-AGIPATI.TTSIDADGK-l..............................
A0A7K3LY48_9ACTN/54-146 ......i--DTPVAEQAQWVLEQLRAGSG.P..DADVA.....A....GRFSDTFLAHVP.A.ED.VADTFD.SLRSL.GT.F.VI.DDYDG...T..EH....Q....AQIDLT.T.EDGSSWQM.HVELDNDGLI...............................
K6WGG5_9MICO/50-140 ......p-PNDAVGRQMSWMLGQMNT--D.P..VSSDV.....S....SRFTEQFQAEVP.P.AQ.WLVMLG.QLRAQ.AP.W.VL.ESVTS...D..GK....A....GSASVV.A.-QGRRYSL.TMTVDDAGRI...............................
A0A4R4MYI2_9ACTN/47-136 .......VPGTPAGKQLGWLLDASSR-PP.I..PEDEL.....K....KHFAASFLKSIP.A.DQ.INQILA.GFKNM.--.-.RL.TKVVE...S..KD....N....ALIALV.Q.AGDSAYEV.VLSVDGSGLI...............................
A0A7G9S5Z3_9MICO/34-129 ......f-PSSELGNQASWVVSQLNSEQG.V..SVEEL.....E....SRLSDKVTEQMS.A.EE.LGSVLEsDVVPD.GP.F.TL.VSFEE...K..DG....K....ALAGLK.N.ESGEVLHM.SIAVDSAN--gki............................
A0A7W8EDF8_9ACTN/33-122 .......VPDSPAGKQLSWYMDAVNR-TP.V..ADKEL.....K....EHLSETFLKEVP.P.EE.FNRLAK.TLAGL.--.-.KV.TELTE...V..KP....D....ALKGKA.S.ASGQEYKT.EISVDDAGKI...............................
A0A4R5C990_9ACTN/71-164 .......LPDTPVGRQARWVLDQLAADGG.P..TVAEA.....G....RRFNTEFLAEVR.A.EQ.VSTVFD.ELRPA.GP.W.VP.VDVDE...A..GA....D....AVVRLH.D.GDGQPWRM.IISVDDDGVI...............................
A0A2Y9AA67_9MICO/54-146 .......LPETRAGQAAAWVLEQLAADEG.P..SAEEA.....Q....ERFADAFLTQVP.A.PQ.VAAVFA.QLRAG.GP.Y.VV.EGYNG...T..ED....A....ARLPLV.A.ADG-RFLL.HVVTEPDGR-m..............................
A0A516X6I1_9ACTN/57-150 ....lqw---QPARDRADRVLQIIGSDAP.V..DPVEA.....L....AMSAPSLTAALY.P.QS.LASAFT.AWQAS.GP.F.TV.TGTED...D..GP....T....AVTHLE.T.ARGVPATL.TVHVGPVGLI...............................
A0A7W7RRC7_9ACTN/44-133 .......IPDSPVGRQLSWYLDAVPR-AP.I..PNAEL.....E....EHLSADFLKAIP.A.DD.FNAFTK.NLKGL.--.-.TL.EKLTA...V..KP....T....RLVGLA.S.VGGHTFVL.TIAVDGDGRI...............................
A0A5C8HNG4_9MICO/50-144 .......IPSTPVGERVQWMIDLINQDAD.I..TVADL.....D....GAFDSTFTDAVA.L.PD.VVELLNvQIRPA.QP.I.VV.TAYEG...S..ES....Q....AVAQVT.G.AVGDPFAI.QMSLTAAGLI...............................
A0A1X1RWW8_MYCCE/51-140 .....id-TRTPPGLRAKQTVDMLNSDWP.I..GPVGV.....R....TLAAPDVVES--.-.--.VEHSME.ELWWD.RP.F.TV.GGVAI...G..AG....A....ATLQLI.T.SYGARQNV.RIHTGDDTL-v..............................
A0A2U0H3S9_9MICO/46-137 .......IPSNPVGTQAAWVLTEING-AP.S..EQAEF.....E....GRFDPIMFEQMA.V.SD.LQQVFE.QLRAA.AP.W.AP.VAYEG...T..ET....Q....ARVTIE.S.PQV-TYDM.SVSVGDDG--sm.............................
A0A646KKS9_STRJU/18-110 .....ad--GSPMGEAARWAVNLLTAPDI.A..SDEEM.....A....ARFMPTFGAG-V.A.GK.FSPTLR.EWRAQ.GP.Y.TV.EDYQA...V..AH....K....SWVTLT.G.PAGERHTL.SLTLDSNGVI...............................
A0A4S5E698_9MICC/57-150 .......IPDSPVGMQVRWVLDQLAADDG.P..DEEEA.....T....ERFAPEFLAEVP.A.DE.LAATFD.QLRAL.GP.F.VL.ETYQE...H..GP....G....AQGDLT.G.AAGQEYLL.SISLDGEERI...............................
F6EHC3_HOYSD/49-138 .......LPETPAGQQVSWFLEASSQ-PP.I..PPDEF.....T....ERMSPEFLAEIS.P.EV.INEVL-.--MAV.GP.L.EP.TEVQS..aT..DD....A....IVVSIN.S.ADG-QLTL.TLRVNDDGMI...............................
A0A4R4PCF3_9ACTN/39-108 ......p-PDTPVGRQLAWLLEAARR-LP.V..SEAEA.....R....AHLAPALFESLG.T.AG.LNDMLR.AAAGP.--.-.--.-----...-..--....-....------.-.--------.----------gtlrldsyraqrepra...............
A0A0J6WB15_MYCCU/36-123 ......i--NTPQGLRAKQTMDMLNSDWP.I..GENGV.....R....TLAAPQVLEA--.-.--.VGVTMD.RMWWD.RP.F.TV.TKVDV...G..AG....S....ATLHVL.T.SYGVAQTI.ELRTDDAGMV...............................
A0A2A7NGY9_MYCAG/28-117 .....id-TNTPQGLRAKQVMDMLNSDWP.I..GPNGI.....R....TLAVPEKMED--.-.--.VGVTMD.KIWWD.RP.F.TL.TGVEI...G..AG....H....ATLHVL.T.SYAVAQTI.ELRTNDAGLV...............................
A0A7G7BN89_9ACTN/24-113 .salagp---------CRWAMGLLTAPDL.P..TEEEL.....A....PSLVPGFLDK-Y.P.RG.FAATLD.EWRKL.GP.F.TV.KIYQP...V..AH....K....GWLVLT.D.PSGRDFSL.TVIIDSTGLV...............................
A0A7W0HQ83_9ACTN/29-118 .......IPDSAVGRQLQWYLDAVNR-TP.L..PESEL.....A....EHLSKDFLQDVP.P.KE.FNEIAA.TLAGL.--.-.RV.DELTE...V..EP....E....ALVARV.S.IPAQVYKA.EISVDDQGKI...............................
A0A4Y9MY93_9MYCO/37-126 .....ig-TSTPQGLRAKQTMDMVNSDWP.I..GDINV.....G....TMAVPEQVDH--.-.--.IIDAMG.NLWWD.RP.I.TV.TGVNI...G..AG....N....ATLHVE.T.SYGADQDI.ELRTDDAGLV...............................
F5YS86_MYCSD/29-118 .....is-TKTPPGLRAKQTMDMLNSDWP.I..GPVGV.....A....TLAAPDKVDQ--.-.--.VVTTME.SLWWD.RP.F.QL.DSVDI...S..AG....A....ATLHLT.T.SYGAHQDI.RIRTDDNGMV...............................
A0A239BGQ3_9ACTN/46-135 .......IPDSPAGRQLRWFLDAPSR-AP.L..TESEL.....G....EHVNAAYLQALT.V.DG.FNAFL-.--KNA.TG.F.QL.EELTT...V..TP....T....ALVGTG.A.IGSQKFVL.QLRVDAAGKI...............................
A0A444PRN8_9MICO/56-149 .......IPETVVGEHISWAIDALNGDIE.V..TPASV.....E....ERLDQAMLDAVT.G.EQ.LVDIVD.QLGAG.KP.W.VP.TSYDG...T..DA....Q....ATATIE.S.ESQGSLDV.QASVDAEGLI...............................
G7CF05_MYCT3/49-138 .....ip-TGTPQGLRAKQTMDMLNSDWP.I..GEPSV.....S....TLAAPEHVAE--.-.--.VTESME.TLWWD.RP.I.TL.TAVDI...G..AG....T....ATLRVR.N.SYGAEQDI.ELRVDDESLV...............................
A0A2V5L5M5_9MICC/17-110 .......VPATPAGKQLAWLLDASRA-LP.I..DPATV.....K....GHFDAAFLAQVR.P.TK.INQILT.AVTPP.GG.L.EV.TSIVP..gS..RP....S....HLVAVV.E.SGEGKLQL.SLATQPEGKI...............................
A0A0K1PHY3_9DELT/33-125 .......VPATPAGEGLAWFVRSINDAHG.V.vTEDEL.....V....ERFSGDFLSKVP.A.SQ.LVQLSK.QFGQQiGN.V.TL.ESVEE..qS..PL....A....LVAKLG.S.AQG-LLRV.SVAVE-----pe.............................
A0A7W9IIK1_9ACTN/61-150 .......IPDSPAGRQLRWFLEALSR-AP.I..AESEL.....R....EHFNAAYLASVT.P.QG.FNDFLK.---QA.AG.F.RL.ATFTK...V..TP....T....ALAGTG.K.LAGETFTF.RIGVDKKGKI...............................
A0A1V0AA61_9ACTN/35-125 .......VPDSSVGKQLQWYLDAVNR-TP.I..PDGEL.....S....EHLSETFLKEVP.A.AK.FNELAK.DLAGL.--.-.KL.EELSS...T..KP....T....ELAGVT.SiPAGQKYDT.KISVDDDGKI...............................
A0A1A0MHI6_9MYCO/51-140 .....id-TSTPPGLRAQQTLDMLNSDWP.I..GPVGV.....G....TLAAKDKVEM--.-.--.VRTAME.GLWWD.RP.F.TL.AGVDI...G..AS....V....ATLHLI.S.SYGARQDI.RIHTDDDRWV...............................
A0A0T2L0S9_9MICO/58-150 .......LPDTVLGAHARWVIDAING-TE.V..TPAEA.....A....SHLSAEMLDQIT.A.DQ.LIEVFA.QLEPQ.SP.W.VP.TAVQD...A..GD....Q....AVITIT.P.ASGDALDL.QIVVDGDDLI...............................
A0A0I9U0C3_9MYCO/51-140 .....id-TRTPPGVRAQQTMDMLNSDWP.I..GSVGV.....R....TLASHDMVDS--.-.--.IRTTME.ELWWD.RP.F.TL.DGVDI...S..AS....V....ATLHLI.S.SYGARQDI.RIHTDDDGWV...............................
A0A7I7XQI6_9MYCO/3-92 .....it-TNTPQGVRAKQVMDMLNSDWP.I..GTPGV.....K....TLAVPDAVDY--.-.--.VAHVMD.GMWWE.RP.Y.TL.TGVDV...G..AG....T....ATLHVI.T.SYGAKQQI.ELHTSDST--lv.............................
A0A8J3AA65_9ACTN/50-140 .......LPDTPLGEQLRWLLDVLAD-GP.P..DDAAV.....D....ARFDDAFLAEVS.V.AE.LRQVFA.QFRGD.--.W.TV.TDVDAa.pD..GL....E....GRMRVL.E.AGGADFEV.LAAVE-----pdp............................
A0A5A7WZV7_9MYCO/1-74 .......---------------MVNSDWP.I..GPVGV.....R....TLAVPAQVDS--.-.--.VVAALD.RLWWD.RP.I.TV.TSIDV...G..AG....E....ATLHTL.T.SYGAAQDI.ELRTSDGGLV...............................
#=GC seq_cons ........ssTPsGhpsphhlDhLNushP.l..ssspl.....p....shhusshlcp........lssshs.plhhs.tP.a.sl.sslsh...s..ss....s....Aslplh.s.uhGst.sl.plpsDssGhl...............................
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