#=GF ID   Obc1_cap
#=GF AC   PF21502.1
#=GF DE   Oxalate biosynthetic component 1, cap domain
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF AU   Lazaro Pinto Beatriz;0000-0001-6837-2941
#=GF SE   ECOD:EF23529
#=GF GA   27.00 27.00;
#=GF TC   36.00 92.10;
#=GF NC   26.70 26.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP   Domain
#=GF RC   Paper describing PDB structure 5iky
#=GF RN   [1]
#=GF RM   27226606
#=GF RT   Structural Insights into an Oxalate-producing Serine Hydrolase
#=GF RT   with an Unusual Oxyanion Hole and Additional Lyase Activity.
#=GF RA   Oh J, Hwang I, Rhee S;
#=GF RL   J Biol Chem. 2016;291:15185-15195.
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This domain is found in a group of proteins from proteobacteria
#=GF CC   and fungi, including the bifunctional enzyme Oxalate
#=GF CC   biosynthetic component 1 from Burkholderia pseudomallei (Obc1,
#=GF CC   Swiss:Q63KK6). This entry represents the cap domain of Obc1,
#=GF CC   which adopts an alpha- helical fold, with two layers of
#=GF CC   anti-parallel helices [1].
#=GF SQ   8
#=GS A0A194XF26_9HELO/550-727  AC A0A194XF26.1
#=GS A0A0F5JXE8_9BURK/551-729  AC A0A0F5JXE8.1
#=GS A0A103ELQ8_9BURK/551-729  AC A0A103ELQ8.1
#=GS A0A559M832_9HELO/547-721  AC A0A559M832.1
#=GS A0A1G6NWF0_9BURK/529-706  AC A0A1G6NWF0.1
#=GS Q63KK6_BURPS/551-728      AC Q63KK6.1
#=GS L1LTM8_9PSED/505-681      AC L1LTM8.1
#=GS A0A328YXX5_9BURK/546-717  AC A0A328YXX5.1
A0A194XF26_9HELO/550-727             tsftdalrhlcpifdrreqwlmeqlltlqqe------------------....------------TD.NGLTSSH..SAvsIAHKVRDLIQVAGLHVRYFLEERDRYPAEGA.KAF..RNIHDIQSLNYAYELLLETERDATSYECALRGLATSCN---IDAAGFLVPKHQRKSHDLRFLEYLSSLTCGLTPDRSTVTNVDLRQTHGYSAFMASLYKAV--ey
A0A0F5JXE8_9BURK/551-729             ..............................l-PGAATLAQALSPVLDAY....GKIEDRFAAELRNVpDDLRTDP..AA..LAARVRATANATGANIRFFVEERDRYLDHEY.LVF..NDIYVPQALNFAREVLAQRGQSTDAYDEALAHYGRPGETVLREEASYRIREDQFKSSALRALEYLVSIPCRYNVDRTNVFNTQLRRDPHYSATMALLFHAIRE..
A0A103ELQ8_9BURK/551-729             ...............................LVSATSILGALQPVVDAY....RQIEDRLAQHLAAHaESQPADP..AA..LAEYVLAAARSFGVTIRSFVEELDRYEDHEY.LSA..RYIQIPQALNFARELLTPRGHSIDAYDRALADYARVGETVTHDNASYSVRVDQFKPLPLRCLEYLVGIPCRYNSDYSDVINLRLRQSPRYSATMALLYHALRE..
A0A559M832_9HELO/547-721             ............................dit----AAMSDALRPLHPAF....ESREKWLLEQMASQ.SW--DDN..TK..ITLKVREIIKNAGLYVRYFFEERDRYPPEGAsKFGniHDIYDIQSLNYVYELLQKAGQDAKIIQQGLQDIATSCG---ISRHSLLTHAHQRKSFNLRFLEYLVSLSCSFSPDYTEVSNTSMRERVGYNSFLAGIFKAI--dy
A0A1G6NWF0_9BURK/529-706             .............................ra--IAGPVLAALAPLQPAY....AAREWRFLAALEADaARLPADRqvAA..AGDLALAALRDHGLYARFFVEERDRYPAEGA.GAF..RNVYPLQALNFVRELLADQQRPGGLWDAALQAMAADSG---LAPHAYQVRPAQFKGQDLRFLEFLTSIPCRYTEDRTDIVHTAVRSHPGYSAAMAVLFEAIHE..
Q63KK6_BURPS/551-728                 ...............................LVSADTILDALRPIVDTY....RKVEDRLATHLASA.EALPADP..AA..LAEHVLTAARSFGVTIRSFVEELDRYEDHEY.LVA..RYIQVPQALNFARELLVPRGYSIDAYDRALEDYARPGKTVTREHASYSVRVDQFKPLPLRCLEYLVGIPCRYNGDYSNVVNLGLRQSPRYSATMALLYHALRE..
L1LTM8_9PSED/505-681                 ...............................RVLAEQVLEALTPFRQDYlareRRLLDALDVHLAGQ.AVPPSDW..--..LGELAVRAIADAGLHVRYFIEERDRYPRPLA.NFG..KRLYALQAINFVRELLVEAGRPTLAWDEALATLAASDG---LPPDSYQVERSQFKGADLRLLEYLASIPCRYNRSRTLAVNTELRFDADYSSTMAILFETIHE..
A0A328YXX5_9BURK/546-717             ............................ham----ATLAGALRPLRPAF....ERREQWLRERLARQ.ARGDTGN..--..AARAVRDLVRQAGLYVRYFVEERDRYPAEGA.GAF..RNLYEIQSLNYAWELLQEAGQDASFYENALQDLARACD---IGPQGFLTLPHQRKSADLRFLEYLVSLSCGFSPDRRDVQNLGLRLRPGYNAFLATLFKAVEE..
#=GC seq_cons                        ..................................AsslhsALpPlhsAY....cphEctLttcLAup.sshsuDs..uA..lActVhssl+ssGLalRaFVEERDRYPsctA.tsh..RsIYslQALNFARELLscpGpsssuYDpALpchApsss...lsssSYpV+scQFKutsLRhLEYLVSIPCRYssDRosVsNssLRpcPsYSAsMAlLF+Al+E..
//