#=GF ID   OpcA
#=GF AC   PF07239.15
#=GF DE   Outer membrane protein OpcA
#=GF AU   Moxon SJ;0000-0003-4644-1816
#=GF SE   Pfam-B_17433 (release 10.0)
#=GF GA   26.30 26.30;
#=GF TC   27.50 27.30;
#=GF NC   25.90 25.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF WK   Outer_membrane_protein_OpcA
#=GF CL   CL0193
#=GF RN   [1]
#=GF RM   12706886
#=GF RT   Identification of opcA gene in Neisseria polysaccharea:
#=GF RT   interspecies diversity of Opc protein family. 
#=GF RA   Zhu P, Klutch MJ, Derrick JP, Prince SM, Tsang RS, Tsai CM; 
#=GF RL   Gene 2003;307:31-40.
#=GF DR   INTERPRO; IPR009876;
#=GF DR   SCOP; 1k24; fa;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family consists of several Neisseria species specific OpcA
#=GF CC   outer membrane proteins. Opc (formerly called 5C) is one of the
#=GF CC   major outer membrane proteins and has been shown to play an
#=GF CC   important role in meningococcal adhesion and invasion of both
#=GF CC   epithelial and endothelial cells [1].
#=GF SQ   7
#=GS A0A238HI09_9NEIS/7-225   AC A0A238HI09.1
#=GS A0A0H4IWF5_NEIG1/3-79    AC A0A0H4IWF5.1
#=GS A0A1A9S2D5_9NEIS/32-267  AC A0A1A9S2D5.1
#=GS A0A1X3DEI8_9NEIS/36-272  AC A0A1X3DEI8.1
#=GS Q7DDI3_NEIMB/23-272      AC Q7DDI3.1
#=GS Q5F8B8_NEIG1/24-263      AC Q5F8B8.1
#=GS A0A0H4J5X0_NEIG1/1-98    AC A0A0H4J5X0.1
A0A238HI09_9NEIS/7-225              .........................................................iigavkyh----------------------------------------FND-RHAVRLEGRYARGKAEYTGGAApsEDEPEGLPYGSIVTKNIPRKSYDIRAIYEYNYPIREGMTAIAEAGLGHRVLRDL.....SsRKDE.DAYDRKNVTTYAHIGAGLNIQLPNQFEFTPKVAYNHGLRGRqYSYSDGKIEMKQ-----PHAKGFELDLSVSKTFENGNKLSFGPFYRGWKVFDSDD.ASIlDEETGkQLQINEPKNRMREVGFKL----qytf......
A0A0H4IWF5_NEIG1/3-79               .........................................................gvavylrn------------------------------------------------------------------..------------------------------------------------------.....-.----.-----------------------------------------.---KNRIAIASQDANLNSKGRFVSSGLNVGKQLTGSLGVEFDPYYRHRAIRKSAE.FVS.NTTK-.----------------------tktdsekfne
A0A1A9S2D5_9NEIS/32-267             ....................................ndgrytvslgyvhshaktdplktsgdgvt--------------------------------LQGRADLPLAD-QHAIRTELGYEYRDS-------..DVKV----EGEKIINGANTHNVDVYAGYLYSPSGFKNGGLRVGGGVGYSHGKTDlhshqV.DPDG.DAVDTRANNLYLKAHAEYEQQLGSGWSITPWGEAKVSVHRR.VEDKYTQIEYESDGKYKQNSYSLGLGVDVNKQLNDSLSLTFGPYYRYTRDKA-TS.FTH.EGE--.--TVEVEKTRQHSFGIRGGLRF..........
A0A1X3DEI8_9NEIS/36-272             yretyreytngterlmqergnlwslnggikysfndrhaakiegryshgesdytgqymedsyygea------------------------------------------------------------------..------------VIQNVPRRAYDIRVSYEYTQPLNEKLDLVLETGLGHRTLKDL.....GsRVNQ.YDYDRKNHTLYARVGAGLDIKLPRSFEINPKVAYNHMLHGR.QHS---YHNGYANKFKQSGGRGIEVEVPVSKRFANDSKLSFGPFYRGWKVPDSERiYSV.DDDGR.LWNAREPKNYTHEAGVKL----qysf......
Q7DDI3_NEIMB/23-272                 .................................................................LQTANEFTVHTDLSSISSTRAFLKEKHKAAKHISVRADIPFDA-NQGIRLEAGFGRSKKNIINLET..DENKLGKTKNVKLPTGVPENRIDLYTGYTYTQTLSDSLNFRVGAGLGFESSKDS.....I.KTTK.HTLHSSRQSWLAKVHADLLSQLGNGWYINPWSEVKFDLNSR.YKLNTGVTNLKKDINQKTNGWGFGLGANIGKKLGESASIEAGPFYKQRTYKESGE.FSV.TTKSG.DVSLTIPKTSIREYGLRVGIKF..........
Q5F8B8_NEIG1/24-263                 .................................................................FLGKGEYTVRTDISKQTLKNADLKEKHKVQKNIGFRADMPFDDIHHGMRFEVSHSRDKK-------..DMYVVTESTTKPFGKDVEEKRTDVYAGYTYTQPISEATKLRAGLGLGYEKYKDA.....V.ANEK.GTVSTEREAFYTKAHADLTSDLGGGWYLNPWAEVKVDLDAK.LKHNATVAGVSADINAKTRGWGVGVGANIGKQITDTVGIEAGPFYKHRHFKASGS.FVL.DGG--.--NIRVDPTKINEYGVRVGVKF..........
A0A0H4J5X0_NEIG1/1-98               .................................................................-----------------------------------------------MRFKAEYARSKN-----DA..D----DKRGNAHIANGAIGKMAAVYAGYTYTQPGGESTRFRGGLER--VQVKRY.....L.GEKCcGYACPKSERFTLQADGEIRQNLGEGWFL-------------.-------------------------------------------------------.---.-----.----------------------kl........
#=GC seq_cons                       ................................................................................................................hRhchtathtct.........-........s..lhpss.p+thDlhsuYpYo.sht-shphhsthGlGapphKc......h.t.pp.tshspcppshhh+stAtlp.pLspua.lsPhsthph.lpt+..p.p.thhthptsh..pspuhuhtlshsluKphsss.tlphGPaY+thphhtSsp.ash.ssp.....php...s..pphGh+h..............
//