#=GF ID PA-IIL
#=GF AC PF07472.15
#=GF DE Fucose-binding lectin II (PA-IIL)
#=GF AU Finn RD;0000-0001-8626-2148
#=GF SE Pfam-B_17609 (release 10.0)
#=GF GA 21.00 21.00;
#=GF TC 21.00 21.50;
#=GF NC 20.70 20.40;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 12415289
#=GF RT Structural basis for oligosaccharide-mediated adhesion of
#=GF RT Pseudomonas aeruginosa in the lungs of cystic fibrosis patients.
#=GF RA Mitchell E, Houles C, Sudakevitz D, Wimmerova M, Gautier C,
#=GF RA Perez S, Wu AM, Gilboa-Garber N, Imberty A;
#=GF RL Nat Struct Biol 2002;9:918-921.
#=GF DR INTERPRO; IPR010907;
#=GF DR SCOP; 1uqx; fa;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC In Pseudomonas aeruginosa the fucose-binding lectin II (PA-IIL)
#=GF CC contributes to the pathogenic virulence of the bacterium. PA-IIL
#=GF CC functions as a tetramer when binding fucose. Each monomer is
#=GF CC comprised of a nine-stranded, antiparallel beta-sandwich
#=GF CC arrangement and contains two calcium cations that mediate the
#=GF CC binding of fucose in a recognition mode unique among
#=GF CC carbohydrate-protein interactions [1].
#=GF SQ 37
#=GS T0NUG7_PHOTE/238-343 AC T0NUG7.1
#=GS A0A166VX71_METRR/23-124 AC A0A166VX71.1
#=GS A0A540WA82_9ACTN/41-152 AC A0A540WA82.1
#=GS Q7MZP8_PHOLL/208-310 AC Q7MZP8.1
#=GS T0QCB5_PHOTE/1-63 AC T0QCB5.1
#=GS A0A0F8A4Q3_9HYPO/17-121 AC A0A0F8A4Q3.1
#=GS Q7MZN9_PHOLL/457-563 AC Q7MZN9.1
#=GS Q9HYN5_PSEAE/7-114 AC Q9HYN5.1
#=GS A0A370N7Q0_9BURK/133-241 AC A0A370N7Q0.1
#=GS Q7NX84_CHRVO/7-113 AC Q7NX84.1
#=GS A0A7W7QXD5_KITKI/15-126 AC A0A7W7QXD5.1
#=GS D3VAZ0_XENNA/1-72 AC D3VAZ0.1
#=GS A0A2I5T420_SERS3/13-130 AC A0A2I5T420.1
#=GS A0A1N7SND1_9BURK/7-113 AC A0A1N7SND1.1
#=GS Q8XUA5_RALSO/7-113 AC Q8XUA5.1
#=GS A0A0B1YG86_9BURK/14-128 AC A0A0B1YG86.1
#=GS A0A0B1YI12_9BURK/137-245 AC A0A0B1YI12.1
#=GS A0A1N6J964_9BURK/7-116 AC A0A1N6J964.1
#=GS A0A0D9PDM4_METAN/14-125 AC A0A0D9PDM4.1
#=GS A0A4R4TUK0_9ACTN/15-128 AC A0A4R4TUK0.1
#=GS A0A0J6NMZ4_9NEIS/7-113 AC A0A0J6NMZ4.1
#=GS H2C250_9CREN/1143-1233 AC H2C250.1
#=GS A0A4R0XAP7_9BURK/150-259 AC A0A4R0XAP7.1
#=GS A0A8A8DAF9_9BURK/135-243 AC A0A8A8DAF9.1
#=GS W4LW21_9BACT/15-122 AC W4LW21.1
#=GS Q7MZP7_PHOLL/230-332 AC Q7MZP7.1
#=GS E9E2D9_METAQ/22-125 AC E9E2D9.1
#=GS A0A410UJ14_9GAMM/7-112 AC A0A410UJ14.1
#=GS T0QQA4_PHOTE/157-259 AC T0QQA4.1
#=GS A0A1G9NPD9_9PSED/8-114 AC A0A1G9NPD9.1
#=GS S2L8I0_HALAF/8-114 AC S2L8I0.1
#=GS W6W9D9_RHIS8/5-120 AC W6W9D9.1
#=GS Q7MZN8_PHOLL/234-339 AC Q7MZN8.1
#=GS A0A1N6J938_9BURK/7-113 AC A0A1N6J938.1
#=GS A0A1Q4WNE5_9ACTN/15-126 AC A0A1Q4WNE5.1
#=GS W4LUB4_9BACT/107-219 AC W4LUB4.1
#=GS Q7MZP3_PHOLL/214-319 AC Q7MZP3.1
T0NUG7_PHOTE/238-343 ..............FQLPQSIRFGLIAYNNTNI.QQTVKV.Y.IDD..LLVD.TL...TGK.GEN-.....NLTATKAYT..S.GT.GKVCI.EI....T...GDG.....KPC....KLRYFDNILDGK........PG.....I....ATIGAENGTKDNYNDCVVMLNWPL.......
A0A166VX71_METRR/23-124 .......asqslkl-------------KTNSKF.VQNVRI.K.VDD..QEFE.A-...SGS.GEGN.....NLIFQRKLD..A.PC.KNISA.TFe.yqT...ENGe...kRQS....KLNSGGPYDIGS........YK.....L....LVVVAENGDDADYNDAVFE-----is.....
A0A540WA82_9ACTN/41-152 .............i-SLPAGARITVKAKTNSSL.VQKVSV.T.SKD..RAVDyQF...TGT.GERN.....TVSGQETFT..G.P-.SQLSA.TF....E...YSDsagvfKPS....KLNSGGPYDIGS........YH.....L....MVIVAENGDDSDYNDAILEFSW--ht.....
Q7MZP8_PHOLL/208-310 ..............FQLPQSIRFGLIAYTNTAIhQQTVKV.Y.IDD..LLVD.TF...TGK.GID-.....----TKAYT..S.GT.GKVCI.EI....I...GDG.....KPC....KLRYSYNTLDGK........PG.....T....VTIGAENDANNNYNDSVVVLNWPL.......
T0QCB5_PHOTE/1-63 .............m-------------------.------.Y.IDG..LLIG.RL...TGK.ETT-.....----TKSYT..S.GT.GKICI.EI....E...GNG.....KPC....KLRYSYNTLEGK........PG.....A....VIIGND------------------kfh....
A0A0F8A4Q3_9HYPO/17-121 ......asgnfrsa-----------TIKANADV.LQLVTI.R.VDE..T-DF.RF...TGM.GEAD.....KIIGSTQLP..D.SF.DKIEV.TS...eF...VDG.....QKArpsvELRNMGFSSLGA........GG.....K....LVIVAENGDDESFDDTIIEF----h......
Q7MZN9_PHOLL/457-563 ..............FQLPQSIRFGLTAYVNSDVhQQSINV.Y.IDD..RLVD.TL...TGK.GIS-.....HITDVRTYT..S.GT.GKVCI.EM....I...GEG.....KPG....KLRYAYNTLEAK........PG.....T....AIIGANNGSNDNYDDSVVVLNWPL.......
Q9HYN5_PSEAE/7-114 ..............FTLPANTRFGVTAFANSSG.TQTVNV.L.VNN..ETAA.TF...SGQ.STNN.....AVIGTQVLN..S.GSsGKVQV.QV....S...VNG.....RPS....DLVSAQVILTNE........LN.....F....ALVGSEDGTDNDYNDAVVVINWPL.......
A0A370N7Q0_9BURK/133-241 ..............FNLPPNTAFGVTVLVNSAA.VQTVSV.F.VDDasKPSA.TF...TGS.GTND.....RNLQTQILN..S.GK.GHVRV.IV....E...ANG.....KQS....KLGSRQVDIFQK........AY.....F....GLVASEDGTDNDYNDGLVILNWPL.......
Q7NX84_CHRVO/7-113 ..............FTLPARINFGVTVLVNSAA.TQHVEI.F.VDN..EPRA.AF...SGV.GTGD.....NNLGTKVIN..S.GS.GNVRV.QI....T...ANG.....RQS....DLVSSQLVLANK........LN.....L....AVVGSEDGTDMDYNDSIVILNWPL.......
A0A7W7QXD5_KITKI/15-126 .............i-SLPAGAKVTVKAKTNSTF.TQTVKV.T.SKD..GSVDlLF...TGS.GERN.....TFAGQETIT..G.PS.QLVATfEY...sE...SDGs...vKPS....KLNSGGPYQIGA........YN.....L....MVIVAENGDDADYNDAILEFSW--yt.....
D3VAZ0_XENNA/1-72 .............m-------------------.------.-.---..--VD.TF...TGK.VTY-.....----TKAYT..S.GT.GKVCI.EI....I...GDG.....KPC....KLRYSYNTLDGK........PG.....T....VTIGAENDSNNNYNDSVVVLNWPL.......
A0A2I5T420_SERS3/13-130 ............is--IPANKIVFWSALVQSSA.NQFIQL.K.-DS..NANI.VF...TVQ.GASSsggipTQIGSGFFQ..AdTS.GSYSI.WI....G...TNGg...kSYS....QILWSQDVITSG........SS.....VyfgkYIFASEDAMDYDYNDSFIQLQW--fq.....
A0A1N7SND1_9BURK/7-113 ..............FTLPPNIRFGVTGFANSAG.TQTINV.L.VDN..EVRA.TF...TGQ.SADN.....KVIGSQVLN..S.GK.GNVQI.KV....T...VNN.....KAS....DLVSVQTTLANR........LN.....F....ALVGSEDGTDGDYNDGIAVLNWPL.......
Q8XUA5_RALSO/7-113 ..............FTLPANTSFGVTAFANAAN.TQTIQV.L.VDN..VVKA.TF...TGS.GTSD.....KLLGSQVLN..S.GS.GAIKI.QV....S...VNG.....KPS....DLVSNQTILANK........LN.....F....AMVGSEDGTDNDYNDGIAVLNWPL.......
A0A0B1YG86_9BURK/14-128 ..............FSIPPNTDFRAIFFANAAE.QQHIKL.F.IGD..SNEP.AA...YHK.LTTR.....DGPREATLN..S.GN.GKLRF.EV....T...VNG.....KTS....ATDARLAPINGKksdgspftVN.....F....GIVVSEDGHDSDYNDGIVVLQWPI.......
A0A0B1YI12_9BURK/137-245 ..............FNLPPNIAFGVTALVNSAA.QQTIEV.Y.VDDnaKPAA.TF...QGA.GTQD.....ANLNTQIVN..S.GK.GKVRV.VV....T...ANG.....KPS....KIGSRQVDIFKK........TY.....F....GLVGSEDGTDGDYNDGIAILNWPL.......
A0A1N6J964_9BURK/7-116 ..............FTLPANTNFGVSAFTNSTF.DQTVKI.L.IDG..QVKA.TF...TGH.GMSN.....NLIGSQVLN..S.GK.GAVQV.TV...gT...GSGg...aTPS....SLISGRAILANR........VN.....F....GMVAADEGSDGDFNDSIIELNWPL.......
A0A0D9PDM4_METAN/14-125 aeinfgndwtaqhl-----------KVKTNSKS.VQNVQI.K.VDD..QEF-.QV...NGS.GERN.....NIIFDRQLD..T.PC.KKISA.TF....TyqaANGd...kLAS....KLKFGGPYDIGR........YK.....T....VTVVAENGDDADYNDAIFE-----isg....
A0A4R4TUK0_9ACTN/15-128 .............v-SLPAGADVHVKVKTNSKH.TQQVRLgR.ADG..SVDH.TY...SGS.GDSN.....TVIGNNRIT..AdGK.QLYSA.TFe.ysD...GDGa...mQPS....KLNSGGPYDIGE........YH.....I....MVVVAENGDDADYNDSILEFSW--ht.....
A0A0J6NMZ4_9NEIS/7-113 ..............FTLPPRINFGVTALTNAAY.QQNITV.Y.VDN..EPRA.TF...SGS.GVDD.....RNLGTRVIN..S.GS.GAVRI.AV....T...VNG.....KQS....DLVSSQVVLANR........LN.....L....ALVGAEDGADQDYNDSIVVLNWPL.......
H2C250_9CREN/1143-1233 ..........nvtg-----NLTFPVTVLG--SG.ITTVKV.L.LDG..RLVT.SF...TGN.GTHQ.....VTINTNAYP..D.GD.HQVEV.EV....A...QSD.....GLN....FTASVNVLFQNQ........LK.....S....VAIG--------------------ltqlntt
A0A4R0XAP7_9BURK/150-259 ..............FKLPPNTRFGVTGLVNSAA.AQQIDV.F.IGD.dPKPH.TL...TGKpGTQD.....GQMGTMILE..SdAT.GHVRL.TV....T...ANG.....RES....KVISRQVDLNQT........VY.....F....GLLGSEDGTDNDYNDCLAILNWPL.......
A0A8A8DAF9_9BURK/135-243 ..............FNLPPNIAFGVTALVNSSA.PQTIEV.F.VDDnpTPAA.TF...QGA.GTQD.....ANLNTQIVN..S.GK.GKVRV.VV....T...ANG.....KPS....KIGSRQVDIFKK........TY.....F....GLVGSEDGGDGDYNDGIAILNWPL.......
W4LW21_9BACT/15-122 ..lsgkitqfsmst---------------QSSA.IQNLEI.QdADG..TSLV.EQ...SGQ.GTSH.....FFAAGGRFT..A.GR.NPHTV.TI....T...ANN.....RNS....SVRYSSAMISDT........SGnifevT....HVLASEDGGDGDYNDCFVTL----ts.....
Q7MZP7_PHOLL/230-332 ..............FQLPQSIRFGLIAYTNTTThKQTVNV.Y.IDD..LLVD.TF...TGK.GTD-.....----TKAYT..S.GA.GNVCI.EI....I...GDG.....KPC....KLRYSYNTLDGK........PG.....T....VTIGAENDANNNYNDSVVVLNWPL.......
E9E2D9_METAQ/22-125 .......ewgsqnl-----------KVKANSRS.VQYVRI.K.VDN..EEFE.A-...SGS.GEGN.....TIIFDRKLG..T.PC.KKISA.TFe.yqT...ENGg...kLQS....KLRSGGPYDIGR........YK.....T....LIVVAENGDDADYNDVIFE-----is.....
A0A410UJ14_9GAMM/7-112 ..............FSIPPNTQFGVTAHACSSG.NQLATI.Y.VDG..SQKA.QF...TGS.GIY-.....KLIGDQTLN..S.GS.GKIKV.TV....T...ANG.....KPC....DMQMARSMIASD........TN.....F....ITVGAEDGTDNDYNDTLVDFKWPI.......
T0QQA4_PHOTE/157-259 ..............FQLPQSIRFGLIAYTNTTThQQTVKV.Y.IDD..FLVD.TF...TGK.GTY-.....----TKAYT..S.GT.GKVCI.EI....I...GDG.....KPC....KLRYSYNTLDGK........PG.....T....VTIGAENDSNNNYNDSVVVLNWPL.......
A0A1G9NPD9_9PSED/8-114 ..............FTLPANIRFGATAFANSSG.MQVVNV.L.VDG..NSVA.QF...QGQ.STGN.....EVIGSQVLS..S.GS.GKVQV.TV....S...VNG.....QQS....SLVSAQVVLANK........LN.....V....IVLGSEDGTDNDYNDSVVILNWPL.......
S2L8I0_HALAF/8-114 ..............FTLPANIRFGITALVNSSG.KQIVTV.L.VDG..KTAA.QF...EGQ.STSN.....EVIGSQVLN..S.GS.GDVQI.TV....S...VNG.....QQS....SLTSAQLILANR........LN.....V....VALGSEDSTDNDYNDTVAILNWPL.......
W6W9D9_RHIS8/5-120 ............il--LPPSTNVFVTALTNAAD.LQKVTI.T.VPG..ASPI.LW...QGT.GEGN.....HQIGSTFVMtpS.GS.QDVQA.TVdvqhS...ANGgn.twQES....ALLPGGCS-IGT........MN.....L....QVLLSEDQVDRDYNDAVVQFLW--wv.....
Q7MZN8_PHOLL/234-339 ..............FQLPHNIKLSLSAYGNTAH.QQTIKV.Y.IDD..QLVD.TL...ISQ.GAN-.....SVLGFKNYS..S.ST.GKVCI.EM....I...GDG.....KPC....KLRYAYNTLDEK........PG.....T....AIIGASNGGNNNYNDSIVVLIWS-q......
A0A1N6J938_9BURK/7-113 ..............FTLPANISFGVTAYANSQY.TETLTV.L.VDG..VSKG.TF...SGT.GANE.....VSLGHKVFN..S.GK.GAIQV.TV....S...AHG.....SAS....DLVSTQVVLGGK........AN.....F....ALLASEDGGDGDYNDCVAILNWAI.......
A0A1Q4WNE5_9ACTN/15-126 .............i-SLPAGAQVAVKAKTNSSN.VQKVQL.T.SKD.gSVDL.AF...SGT.GEGN.....APIGQSTVT..G.PAvLTAAF.EF...aA...ADGd...fKPS....NLNSGGPYAIGA........YN.....L....AVVVAENGDDSDYNDTVLEFSW--ht.....
W4LUB4_9BACT/107-219 ...ipfnllpgktt------------QYSMSTQaDDTQEV.V.VKD..ANGN.VLmseSAS.GTHE.....YLIGTGTFP..A.GP.NPHTI.TI....T...ANG.....NTS....SVYHASTPITDD.......dGNfl.elT....HIFASEDGGDGDYNDCFVTL----ts.....
Q7MZP3_PHOLL/214-319 ..............FQLPQSIRFGLTAYNNTNI.QQTVKV.Y.IDD..LLVD.TL...TGK.GTN-.....NPMATKTYT..S.GT.GKVCI.EI....E...GDG.....KPS....KLRYFDNTLDGK........PG.....T....AIIGAENGTNNNYNDCVVILNWPL.......
#=GC seq_cons ...............pLP.shphslpuhsNSst.tQslpl.h.lDs..p.ss.sF...oGp.Gssp.....p.luopshs..S.Gs.Gplpl.pl....s...usG.....+sS....cLtsutshlts+........hs.....h....slluuEsGsDsDYNDullhLsWs........
//
