#=GF ID PSA_CBD
#=GF AC PF18341.5
#=GF DE PSA endolysin C-terminal cell wall binding domain
#=GF AU El-Gebali S;0000-0003-1378-5495
#=GF SE ECOD:EUF00934
#=GF GA 27.00 27.00;
#=GF TC 27.00 38.90;
#=GF NC 26.90 25.00;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP Domain
#=GF CL CL0010
#=GF RN [1]
#=GF RM 17010991
#=GF RT The crystal structure of the bacteriophage PSA endolysin reveals
#=GF RT a unique fold responsible for specific recognition of Listeria
#=GF RT cell walls.
#=GF RA Korndorfer IP, Danzer J, Schmelcher M, Zimmer M, Skerra A,
#=GF RA Loessner MJ;
#=GF RL J Mol Biol. 2006;364:678-689.
#=GF DR INTERPRO; IPR041341;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC This is the C-terminal domain of bacteriophage PSA endolysin.
#=GF CC The C-terminal domain is the cell wall-binding domain (CBD)
#=GF CC which is composed of two structurally homologous subdomains. CBD
#=GF CC comprises two copies of a beta-barrel-like folds, which are held
#=GF CC together by means of swapped beta-strands. The observed
#=GF CC structure of the CBD sub-domains from Listeriaphage endolysin
#=GF CC (N-acetyl-muramoyl-l-alanine amidase), could be the result of
#=GF CC either a gene duplication during evolution of the CBD or the
#=GF CC pick-up of another functionally equivalent coding sequence,
#=GF CC followed by swapping of the respective ancestral leading
#=GF CC beta-strands [1].
#=GF SQ 27
#=GS R4ICC5_9CAUD/176-234 AC R4ICC5.1
#=GS A0A0B5CTW5_9CAUD/261-315 AC A0A0B5CTW5.1
#=GS A0A2U8UUL2_9CAUD/253-307 AC A0A2U8UUL2.1
#=GS Q8W5Y8_9CAUD/182-240 AC Q8W5Y8.1
#=GS A0A2U8UUL2_9CAUD/176-234 AC A0A2U8UUL2.1
#=GS A8ATR6_9CAUD/155-218 AC A8ATR6.1
#=GS Q8W5Y8_9CAUD/259-313 AC Q8W5Y8.1
#=GS A8ATJ1_9CAUD/189-247 AC A8ATJ1.1
#=GS A0A0B5D123_9CAUD/184-242 AC A0A0B5D123.1
#=GS A0A059T7X1_9CAUD/184-242 AC A0A059T7X1.1
#=GS W7CCJ6_9LIST/288-348 AC W7CCJ6.1
#=GS A0A0B5CTW5_9CAUD/184-242 AC A0A0B5CTW5.1
#=GS A0A2U8UV87_9CAUD/176-234 AC A0A2U8UV87.1
#=GS A0A059T7X1_9CAUD/261-315 AC A0A059T7X1.1
#=GS W7CJF0_9LIST/181-245 AC W7CJF0.1
#=GS R4ICC5_9CAUD/253-307 AC R4ICC5.1
#=GS A0A2U8UV78_9CAUD/234-288 AC A0A2U8UV78.1
#=GS A8ASL5_BPA50/157-215 AC A8ASL5.1
#=GS W7CJF0_9LIST/255-315 AC W7CJF0.1
#=GS A0A2U8UV78_9CAUD/157-215 AC A0A2U8UV78.1
#=GS W7BF65_9LIST/28-88 AC W7BF65.1
#=GS A8ATJ1_9CAUD/262-320 AC A8ATJ1.1
#=GS A0A2U8UV87_9CAUD/253-307 AC A0A2U8UV87.1
#=GS A8ASL5_BPA50/234-288 AC A8ASL5.1
#=GS A8ATR6_9CAUD/227-287 AC A8ATR6.1
#=GS A0A0B5D123_9CAUD/262-315 AC A0A0B5D123.1
#=GS W7CCJ6_9LIST/215-278 AC W7CCJ6.1
R4ICC5_9CAUD/176-234 .........NRHDGKVVDSAPLLPKMDF.KSNPVRMYKSGTEFLVYEHNQYWYKTYIDD...--KLYYMYKSFC
A0A0B5CTW5_9CAUD/261-315 ....akdlr----------IPVWNNTKL.SSGKIKWYAPNTKLAWYNNGKGYLELWYPS...-DGWYYTANYFL
A0A2U8UUL2_9CAUD/253-307 ....akdlr----------IPVWNNTKL.NSGKIKWYSPGTKLSWYDNKKGYLELWYEK...-DGWYYTANYFL
Q8W5Y8_9CAUD/182-240 .........NRHSGAVVDSVPMLSKMDF.KSSPIKMYKAGSSLLVYEHNKYWYKAYIND...--KLCYIYKSFC
A0A2U8UUL2_9CAUD/176-234 .........NRHDGKVVDSAPLLPKMDF.KSNPVRMYKSGTEFLVYEHNQYWYKTYIDD...--KLYYMHKSFC
A8ATR6_9CAUD/155-218 .........ENINIVIKDVGYFQDKPQFlNSKSVRQWKHGTKVKLTKHNSHWYTGVVKDg.nKSVRGYIYHSMA
Q8W5Y8_9CAUD/259-313 ....akdlr----------IPVWNNTKL.NSGKIKWYSPGTKLSWYDNKKGYLELWYEK...-DGWYYTANYFL
A8ATJ1_9CAUD/189-247 .........NRHDGAVVDSIPALPKPDF.KTVPSKMYKAGSELLVYDHNKYWYKTYIND...--KLCYIYKSFC
A0A0B5D123_9CAUD/184-242 .........NRHDGKVVDSAPLLPKMDF.KSSPFRMYKSGTEFLVYEHNQYWYKTYIND...--KLYYMYKSFC
A0A059T7X1_9CAUD/184-242 .........NRHDGKVVDSAPLLTKMDF.KSSPFRMYKAGTEILVYEHNQYWYKTYIDD...--KLYYMYKSFC
W7CCJ6_9LIST/288-348 ........d-KYSGTVQAFAIWWDNSKL.SSGELFTQAPGTAVKHYPSNNNLKSAYYPK...RTKVFFTPNYWL
A0A0B5CTW5_9CAUD/184-242 .........NRHDGKVVDSAPLLTKMDF.KSSPFRMYKSGTEFLVYEHNQYWYKTYIDD...--KLYYMYKSFC
A0A2U8UV87_9CAUD/176-234 .........NRHSGQVVDSAPLLPKTDF.KSNPARMYKSGTEFLVYEHNQYWYKTYIDD...--KLYYMYKSFC
A0A059T7X1_9CAUD/261-315 ....akdlr----------IPVWNNTKL.NSGKIKWYAPNTKLAWYNNGKGYLELWYEK...-DGWYYTANYFL
W7CJF0_9LIST/181-245 .........NAIAATVQDIAPLMPKPQFkGQSPLRKWKTGTKIKVYKHNKYWYKTYVPDkngKLVLGFIYHGFL
R4ICC5_9CAUD/253-307 ....akdlr----------IPVWNNTKL.NSGKIKWYAPGVKLAWYDNKKGYLELWYEK...-DGWYYTANYFL
A0A2U8UV78_9CAUD/234-288 ....akdlr----------IPVWNNTKL.NSGKIKWYAPNTKLAWYNNGKGYLELWYPS...-DGWYYTANYFL
A8ASL5_BPA50/157-215 .........NRYEGKVIDSAPLLPKMDF.KSSPFRMYKVGTEFLVYDHNQYWYKTYIDD...--KLYYMYKSFC
W7CJF0_9LIST/255-315 .........GRISATVQAFAIFWDNESL.NGGEVLTYKVGTKLKHYPERAGMKSAYFSK...QKKVFYTANYWL
A0A2U8UV78_9CAUD/157-215 .........NRYEGKVIDSAPLLPKMDF.KSSPFRMYKVGTEFLVYDHNQYWYKTYIND...--KLYYMYKSFC
W7BF65_9LIST/28-88 .........GRISATVQAFAIFWDNQNL.RGGQILTYKPGTKLKHYPEKIGLKSAYFTK...QKKVFYTPNYWL
A8ATJ1_9CAUD/262-320 kiksvkdlr----------IPVWDNTKL.SSGKIKWYAPNTKLSWYNNKKGYLELYYPN...-QGWYYTANYFL
A0A2U8UV87_9CAUD/253-307 ....akdlr----------IPVWNNTKL.SSGKIKWYKPGTKLSWYNNKKGYLELWYTN...-DGWYYTANYFL
A8ASL5_BPA50/234-288 ....akdlr----------IPVWNNIKL.NSGKIKWYAPNVKLAWYNYRRGYLELWYPN...-DGWYYTAEYFL
A8ATR6_9CAUD/227-287 ........g-SVNATINAHAFCWDNKKL.NGGDFINLKRGFKGITHPASDGFYPLYFAS...RKKTFYIPRYMF
A0A0B5D123_9CAUD/262-315 .....kdlr----------IPVWDNTRL.NSGKIKWYKPGTKLSWYDNKKGYLELWYDK...-DGWYYTANYFL
W7CCJ6_9LIST/215-278 .........TNVAARVVNGAPLLSHTQFkEKHPLRLWKTGTKIQVRKFNTYWYKTSVQVd.gQWKTGYIYHSMV
#=GC seq_cons ..........thth.l.s.hPlhsphch.pSu.l+hYKsGTclhhYcpsphahchahsc.....thYYhhp.Fh
//
