#=GF ID PanZ
#=GF AC PF12568.12
#=GF DE Acetyltransferase (GNAT) domain, PanZ
#=GF PI DUF3749;
#=GF AU Gavin OL;
#=GF AU Bateman A;0000-0002-6982-4660
#=GF SE Prosite
#=GF GA 22.00 22.00;
#=GF TC 22.00 22.00;
#=GF NC 21.90 21.90;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP Domain
#=GF CL CL0257
#=GF RN [1]
#=GF RM 25910242
#=GF RT The structure of the PanD/PanZ protein complex reveals negative
#=GF RT feedback regulation of pantothenate biosynthesis by coenzyme A.
#=GF RA Monteiro DC, Patel V, Bartlett CP, Nozaki S, Grant TD, Gowdy JA,
#=GF RA Thompson GS, Kalverda AP, Snell EH, Niki H, Pearson AR, Webb ME;
#=GF RL Chem Biol. 2015;22:492-503.
#=GF DR INTERPRO; IPR040448;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC This domain family is found in bacteria, and is approximately 40
#=GF CC amino acids in length. The proteins in this family are members
#=GF CC of the acetyltransferases of the GNAT family. Family members
#=GF CC such as PanZ has been shown to be involved in the biosynthesis
#=GF CC of Coenzyme A (CoA). CoA is a ubiquitous and essential cofactor,
#=GF CC synthesized from the precursor pantothenate. In all organisms,
#=GF CC the final step in pantothenate biosynthesis relies on the
#=GF CC presence of beta-alanine, which comes from different sources in
#=GF CC bacteria, yeast, and plants. In bacteria, beta-alanine is
#=GF CC derived by the action of alpha-decarboxylase (ADC) enzyme. PanZ
#=GF CC promotes the activation of the zymogen, PanD, to form aspartate
#=GF CC alpha-decarboxylase (ADC) in a CoA-dependent manner. Thereby,
#=GF CC playing an essential role in the biosynthetic pathway to
#=GF CC pantothenate and the regulation of CoA biosynthesis. Structure
#=GF CC and function studies show that direct interaction of PanD with
#=GF CC the PanZ Arg43-Leu46 loop promotes PanD to adopt a reactive
#=GF CC conformation, which leads to activation [1].
#=GF SQ 236
#=GS A0A2V1H4V0_9GAMM/3-128 AC A0A2V1H4V0.1
#=GS A0A420ELA2_9ALTE/2-123 AC A0A420ELA2.1
#=GS R4YK43_OLEAN/2-128 AC R4YK43.1
#=GS S2KLB2_HALAF/3-121 AC S2KLB2.1
#=GS A0A097R7A6_HAFAL/2-136 AC A0A097R7A6.1
#=GS A0A5R9LMZ7_9ENTR/2-125 AC A0A5R9LMZ7.1
#=GS A0A2U3N464_9GAMM/3-109 AC A0A2U3N464.1
#=GS A0A1E7QYY5_9GAMM/5-108 AC A0A1E7QYY5.1
#=GS A0A1X7APY1_9GAMM/2-123 AC A0A1X7APY1.1
#=GS A0A2S4HHC0_9GAMM/2-126 AC A0A2S4HHC0.1
#=GS A0A8J7GR66_9ENTR/2-129 AC A0A8J7GR66.1
#=GS B2VJR2_ERWT9/2-127 AC B2VJR2.1
#=GS A0A5R9QJ07_9GAMM/2-129 AC A0A5R9QJ07.1
#=GS A0A656YGA7_SALNE/2-125 AC A0A656YGA7.1
#=GS Q1R076_CHRSD/6-121 AC Q1R076.1
#=GS A0A1B2LW03_9GAMM/2-109 AC A0A1B2LW03.1
#=GS A8AR13_CITK8/5-128 AC A8AR13.1
#=GS A0A2I0FWK6_9GAMM/2-127 AC A0A2I0FWK6.1
#=GS K2JEG4_9GAMM/2-122 AC K2JEG4.1
#=GS A0A369KVI9_9GAMM/6-106 AC A0A369KVI9.1
#=GS W1EII6_KLEPN/2-117 AC W1EII6.1
#=GS A0A384LK62_SHIFL/2-125 AC A0A384LK62.1
#=GS A0A0K1XE38_9GAMM/2-128 AC A0A0K1XE38.1
#=GS A0A368U9E8_9GAMM/2-127 AC A0A368U9E8.1
#=GS A0A0F7M2S3_9GAMM/2-126 AC A0A0F7M2S3.1
#=GS PANZ_ECOLI/2-125 AC P37613.1
#=GS A0A071LTW9_9ENTR/2-125 AC A0A071LTW9.1
#=GS A0A2N5EI28_9GAMM/2-123 AC A0A2N5EI28.1
#=GS A0A3N1IQA1_9ENTR/2-125 AC A0A3N1IQA1.1
#=GS T0P0Q9_PHOTE/2-130 AC T0P0Q9.1
#=GS A0A558NGW9_9GAMM/8-137 AC A0A558NGW9.1
#=GS A0A370QTY9_9GAMM/2-131 AC A0A370QTY9.1
#=GS A0A2I0CNW9_9PSED/2-123 AC A0A2I0CNW9.1
#=GS A6TF74_KLEP7/2-125 AC A6TF74.1
#=GS A0A1G9ITG5_9PSED/2-129 AC A0A1G9ITG5.1
#=GS A0A1H2Z3L3_9GAMM/3-132 AC A0A1H2Z3L3.1
#=GS Q0VM68_ALCBS/3-98 AC Q0VM68.1
#=GS A0A2T5PA26_9PSED/2-129 AC A0A2T5PA26.1
#=GS A0A084A1L1_9GAMM/2-129 AC A0A084A1L1.1
#=GS Q6CZ11_PECAS/2-129 AC Q6CZ11.1
#=GS A0A1N7NJ73_9GAMM/2-99 AC A0A1N7NJ73.1
#=GS A0A143G771_9GAMM/2-113 AC A0A143G771.1
#=GS A0A1R4I078_9GAMM/2-118 AC A0A1R4I078.1
#=GS A0A7T4UU51_9GAMM/9-142 AC A0A7T4UU51.1
#=GS A0A1I7J2V9_9GAMM/2-126 AC A0A1I7J2V9.1
#=GS A0A233RD93_9GAMM/2-120 AC A0A233RD93.1
#=GS K6XAM9_9MICO/47-121 AC K6XAM9.1
#=GS A0A0C4WK31_9GAMM/2-129 AC A0A0C4WK31.1
#=GS A0A1M5EEF7_9GAMM/6-135 AC A0A1M5EEF7.1
#=GS G8Q1H7_PSEO1/2-129 AC G8Q1H7.1
#=GS W1HTA4_KLEPN/2-82 AC W1HTA4.1
#=GS A0A366W723_9GAMM/2-137 AC A0A366W723.1
#=GS A0A090IL75_9GAMM/2-135 AC A0A090IL75.1
#=GS A0A485AP43_KLUCR/2-125 AC A0A485AP43.1
#=GS A0A1G7UYT3_9GAMM/3-117 AC A0A1G7UYT3.1
#=GS V2UGZ2_9GAMM/2-115 AC V2UGZ2.1
#=GS E1SHE9_PANVC/2-127 AC E1SHE9.1
#=GS A0A1S8CFU8_9GAMM/2-129 AC A0A1S8CFU8.1
#=GS A0A0Q4NPP5_9GAMM/2-127 AC A0A0Q4NPP5.1
#=GS A0A2N7TGK5_9GAMM/8-113 AC A0A2N7TGK5.1
#=GS A0A089Q2Z5_9ENTR/2-125 AC A0A089Q2Z5.1
#=GS A0A4R3YSZ6_9GAMM/2-130 AC A0A4R3YSZ6.1
#=GS A0A4V1IP72_9GAMM/2-121 AC A0A4V1IP72.1
#=GS Q8X6S6_ECO57/2-125 AC Q8X6S6.1
#=GS A0A2S2FH64_9GAMM/12-113 AC A0A2S2FH64.1
#=GS A1SZI5_PSYIN/3-137 AC A1SZI5.1
#=GS Q9HU40_PSEAE/2-129 AC Q9HU40.1
#=GS A0A014NBP6_9GAMM/2-127 AC A0A014NBP6.1
#=GS A0A085A3J0_9ENTR/2-125 AC A0A085A3J0.1
#=GS A0A078LHL3_CITKO/2-125 AC A0A078LHL3.1
#=GS A0A2T5HHS0_9PSED/2-129 AC A0A2T5HHS0.1
#=GS A0A078LQV1_9PSED/2-129 AC A0A078LQV1.1
#=GS A0A024HNW1_PSEKB/2-127 AC A0A024HNW1.1
#=GS A0A4S2T6V2_9ACTN/87-151 AC A0A4S2T6V2.1
#=GS A0A291P2U5_9GAMM/2-115 AC A0A291P2U5.1
#=GS A0A1I3G6Z9_9GAMM/2-133 AC A0A1I3G6Z9.1
#=GS A0A0C5VDJ7_9GAMM/9-121 AC A0A0C5VDJ7.1
#=GS A0A455V0B9_9GAMM/1-71 AC A0A455V0B9.1
#=GS A0A447LX87_SALBN/2-125 AC A0A447LX87.1
#=GS A0A385Z7A8_9PSED/2-129 AC A0A385Z7A8.1
#=GS A0A0D6STP3_9PSED/2-129 AC A0A0D6STP3.1
#=GS A0A8H9YX05_9PSED/2-125 AC A0A8H9YX05.1
#=GS A0A1T1HBP9_OCELI/2-134 AC A0A1T1HBP9.1
#=GS A0A6I6EVC3_9GAMM/2-127 AC A0A6I6EVC3.1
#=GS A0A859PJ78_9ENTR/2-124 AC A0A859PJ78.1
#=GS A0A7Y3XAV9_9GAMM/4-130 AC A0A7Y3XAV9.1
#=GS A0A1P8R7G1_9GAMM/3-127 AC A0A1P8R7G1.1
#=GS A0A8J6UJ96_9GAMM/2-128 AC A0A8J6UJ96.1
#=GS A0A663BJQ1_9ENTR/2-125 AC A0A663BJQ1.1
#=GS A0A2N0WVV4_9GAMM/2-137 AC A0A2N0WVV4.1
#=GS E9CLI9_9GAMM/2-131 AC E9CLI9.1
#=GS A0A2I5T2X2_SERS3/2-129 AC A0A2I5T2X2.1
#=GS B4EX09_PROMH/2-130 AC B4EX09.1
#=GS A0A1I1H2D6_9GAMM/6-135 AC A0A1I1H2D6.1
#=GS A0A4R6TYP9_9GAMM/2-125 AC A0A4R6TYP9.1
#=GS D4E0A0_SEROD/2-129 AC D4E0A0.1
#=GS S3MR44_9GAMM/2-111 AC S3MR44.1
#=GS A0A662ZF60_9GAMM/17-122 AC A0A662ZF60.1
#=GS A9MM82_SALAR/2-125 AC A9MM82.1
#=GS E0SFI3_DICD3/2-131 AC E0SFI3.1
#=GS A0A2A3XD27_9GAMM/4-127 AC A0A2A3XD27.1
#=GS A0A1W6B3J4_9GAMM/2-127 AC A0A1W6B3J4.1
#=GS A0A090V3K3_PSEVU/2-125 AC A0A090V3K3.1
#=GS A0A7D5IHV3_9PSED/2-129 AC A0A7D5IHV3.1
#=GS A0A0J5KZK3_PLUGE/2-125 AC A0A0J5KZK3.1
#=GS D8MY72_ERWBE/2-127 AC D8MY72.1
#=GS A0A7T4UR00_9GAMM/2-126 AC A0A7T4UR00.1
#=GS A0A1Y0CZ19_9GAMM/2-119 AC A0A1Y0CZ19.1
#=GS A0A7Y8X4W4_9ACTN/86-159 AC A0A7Y8X4W4.1
#=GS A0A4Z0W700_9GAMM/2-107 AC A0A4Z0W700.1
#=GS A0A1Q5MZM9_9ACTN/85-154 AC A0A1Q5MZM9.1
#=GS C4L9Y5_TOLAT/3-125 AC C4L9Y5.1
#=GS A0A1Z9Z3L3_9GAMM/3-109 AC A0A1Z9Z3L3.1
#=GS A0A1G9QE60_9GAMM/2-131 AC A0A1G9QE60.1
#=GS A0A4Q9RFN2_9GAMM/2-129 AC A0A4Q9RFN2.1
#=GS A0A839IP29_9GAMM/2-122 AC A0A839IP29.1
#=GS A0A0B3BX64_9PSED/2-129 AC A0A0B3BX64.1
#=GS A0A510X9I4_9GAMM/2-109 AC A0A510X9I4.1
#=GS M5DN24_9GAMM/2-134 AC M5DN24.1
#=GS A0A372M2V7_9ACTN/104-193 AC A0A372M2V7.1
#=GS W0HQP9_9GAMM/2-130 AC W0HQP9.1
#=GS W7PYR5_9GAMM/5-105 AC W7PYR5.1
#=GS A0A380PG60_YERPE/2-129 AC A0A380PG60.1
#=GS A0A853I0F4_9GAMM/2-127 AC A0A853I0F4.1
#=GS A0A095TS71_9GAMM/2-126 AC A0A095TS71.1
#=GS A0A1J7C8V5_9GAMM/2-130 AC A0A1J7C8V5.1
#=GS W1N6V1_9GAMM/6-124 AC W1N6V1.1
#=GS D4GD63_PANAM/5-130 AC D4GD63.1
#=GS A0A839T2I2_AZOMA/2-126 AC A0A839T2I2.1
#=GS U3TZP9_9ENTR/1-121 AC U3TZP9.1
#=GS Q32AS4_SHIDS/2-125 AC Q32AS4.1
#=GS H5V3I4_ATLHE/19-142 AC H5V3I4.1
#=GS A0A085G013_9ENTR/2-125 AC A0A085G013.1
#=GS A0A0M2KGV9_9GAMM/2-127 AC A0A0M2KGV9.1
#=GS F0KGL3_ACICP/3-111 AC F0KGL3.1
#=GS A0A5J6QGR5_9PSED/2-131 AC A0A5J6QGR5.1
#=GS A0A378AMH1_KLEPO/2-125 AC A0A378AMH1.1
#=GS A0A1I4YWB3_9GAMM/2-127 AC A0A1I4YWB3.1
#=GS R8ASS8_PLESH/2-128 AC R8ASS8.1
#=GS A0A241W3F6_9GAMM/13-108 AC A0A241W3F6.1
#=GS L0M0P9_ENTBF/2-125 AC L0M0P9.1
#=GS H0J5Q2_9GAMM/6-129 AC H0J5Q2.1
#=GS A0A1X0WFS7_9GAMM/2-125 AC A0A1X0WFS7.1
#=GS A0A4P7J6V1_9ENTR/2-125 AC A0A4P7J6V1.1
#=GS A0A7W4W547_9GAMM/2-117 AC A0A7W4W547.1
#=GS H2G061_OCESG/2-120 AC H2G061.1
#=GS A0A4Z0MW02_SALET/2-125 AC A0A4Z0MW02.1
#=GS V2UWG3_9GAMM/2-114 AC V2UWG3.1
#=GS A0A1G6NAI9_9GAMM/2-111 AC A0A1G6NAI9.1
#=GS A0A0J8VGP3_9ENTR/2-125 AC A0A0J8VGP3.1
#=GS A0A1K1W7F2_9GAMM/5-126 AC A0A1K1W7F2.1
#=GS A0A1H6R532_9GAMM/7-136 AC A0A1H6R532.1
#=GS A0A345P378_9GAMM/19-118 AC A0A345P378.1
#=GS A0A1H4EPM9_9GAMM/2-129 AC A0A1H4EPM9.1
#=GS A0A1J0VEX9_9GAMM/3-122 AC A0A1J0VEX9.1
#=GS A0A6B2FNY6_9ENTR/2-125 AC A0A6B2FNY6.1
#=GS A0A2S6VNX7_9GAMM/2-127 AC A0A2S6VNX7.1
#=GS A0A6I4V6Q5_9GAMM/2-127 AC A0A6I4V6Q5.1
#=GS A0A2G8EHJ7_9GAMM/2-127 AC A0A2G8EHJ7.1
#=GS C5B985_EDWI9/2-129 AC C5B985.1
#=GS A0A427K5N7_9GAMM/2-124 AC A0A427K5N7.1
#=GS A0A0P7E7B5_9GAMM/5-123 AC A0A0P7E7B5.1
#=GS A0A5B8SQM7_9GAMM/2-134 AC A0A5B8SQM7.1
#=GS A4VRW7_PSEU5/15-142 AC A4VRW7.1
#=GS A0A0H3H464_KLEPH/2-125 AC A0A0H3H464.1
#=GS A0A0L0AUG8_9ENTR/2-125 AC A0A0L0AUG8.1
#=GS A0A2T6E3D7_9GAMM/2-115 AC A0A2T6E3D7.1
#=GS A0A1M7HQA6_9GAMM/2-132 AC A0A1M7HQA6.1
#=GS A0A2V1HCT8_9GAMM/2-129 AC A0A2V1HCT8.1
#=GS A0A1T4NJD7_9GAMM/2-127 AC A0A1T4NJD7.1
#=GS A0A0L7T6T6_9GAMM/2-127 AC A0A0L7T6T6.1
#=GS A0A1B8Q9J2_9GAMM/6-128 AC A0A1B8Q9J2.1
#=GS A0A1H0K3T6_9PSED/2-129 AC A0A1H0K3T6.1
#=GS A0A1H1WLN3_9PSED/2-126 AC A0A1H1WLN3.1
#=GS A0A0N0IBQ6_9GAMM/2-129 AC A0A0N0IBQ6.1
#=GS D3UZC0_XENBS/2-131 AC D3UZC0.1
#=GS A0A7W7P000_9PSED/2-131 AC A0A7W7P000.1
#=GS A0A418YKT7_9GAMM/2-126 AC A0A418YKT7.1
#=GS M4U761_9GAMM/3-137 AC M4U761.1
#=GS A0A2X4SWR0_SALER/2-125 AC A0A2X4SWR0.1
#=GS U3AW34_PSEA4/2-129 AC U3AW34.1
#=GS A0A250B0V4_9GAMM/2-129 AC A0A250B0V4.1
#=GS K8WH96_9GAMM/2-131 AC K8WH96.1
#=GS Q7N005_PHOLL/2-131 AC Q7N005.1
#=GS A0A1J4QAH0_9GAMM/17-120 AC A0A1J4QAH0.1
#=GS A0A1I0AJ49_9GAMM/2-139 AC A0A1I0AJ49.1
#=GS A0A845SU55_9GAMM/2-130 AC A0A845SU55.1
#=GS A0A085G3F8_9GAMM/2-124 AC A0A085G3F8.1
#=GS D2TLI2_CITRI/2-125 AC D2TLI2.1
#=GS R9PM78_AGAAL/4-122 AC R9PM78.1
#=GS A0A1G9E4A1_9GAMM/8-105 AC A0A1G9E4A1.1
#=GS A0A1B7JYH8_9GAMM/2-131 AC A0A1B7JYH8.1
#=GS A0A562IKI6_9GAMM/2-121 AC A0A562IKI6.1
#=GS A0A4Y7ZTY1_9GAMM/2-137 AC A0A4Y7ZTY1.1
#=GS A0A421DRA7_9GAMM/2-129 AC A0A421DRA7.1
#=GS A0A2I8Q160_9ENTR/2-125 AC A0A2I8Q160.1
#=GS E1VA13_HALED/2-129 AC E1VA13.1
#=GS A0A4R3IAT0_9GAMM/4-106 AC A0A4R3IAT0.1
#=GS A0A8J7GWH9_9ENTR/2-129 AC A0A8J7GWH9.1
#=GS A0A317NAY6_9GAMM/10-125 AC A0A317NAY6.1
#=GS S6AJW9_PSERE/2-129 AC S6AJW9.1
#=GS A0A378E782_KLEPR/2-125 AC A0A378E782.1
#=GS A0A7U7EJS9_9PSED/2-129 AC A0A7U7EJS9.1
#=GS A0A085U6J5_YERRU/2-129 AC A0A085U6J5.1
#=GS A0A4P8YGP7_9ENTR/2-125 AC A0A4P8YGP7.1
#=GS A0A222FG48_9GAMM/2-134 AC A0A222FG48.1
#=GS A0A0G4JSM8_9GAMM/2-129 AC A0A0G4JSM8.1
#=GS A0A4R6EIV8_9ENTR/2-125 AC A0A4R6EIV8.1
#=GS A0A443IEA8_9GAMM/2-127 AC A0A443IEA8.1
#=GS A0A248KGY6_9ENTR/2-125 AC A0A248KGY6.1
#=GS A0A0X8HBN1_9GAMM/6-105 AC A0A0X8HBN1.1
#=GS A0A240ADM3_SERFI/2-129 AC A0A240ADM3.1
#=GS A0A2N7ULF8_9GAMM/3-128 AC A0A2N7ULF8.1
#=GS E3GAY4_ENTLS/2-125 AC E3GAY4.1
#=GS W1DGF1_KLEPN/1-58 AC W1DGF1.1
#=GS A0A4R1NE46_9GAMM/2-130 AC A0A4R1NE46.1
#=GS W0HT02_9GAMM/2-130 AC W0HT02.1
#=GS A0A3T1DXA6_9GAMM/4-125 AC A0A3T1DXA6.1
#=GS A0A1H2EJ22_9PSED/2-124 AC A0A1H2EJ22.1
#=GS A0A1H0J6Q5_9GAMM/6-128 AC A0A1H0J6Q5.1
#=GS A0A2T4J7S6_FUSBL/194-270 AC A0A2T4J7S6.1
#=GS I2JHY8_9GAMM/2-126 AC I2JHY8.1
#=GS A0A2D2MCI6_9PSED/2-127 AC A0A2D2MCI6.1
#=GS A0A484ZBU7_9ENTR/2-125 AC A0A484ZBU7.1
#=GS A0A2V1HI16_9GAMM/2-115 AC A0A2V1HI16.1
#=GS A0A2J4R4W9_9ENTR/2-125 AC A0A2J4R4W9.1
#=GS A0A368NKI8_9GAMM/2-127 AC A0A368NKI8.1
#=GS I2B469_SHIBC/2-125 AC I2B469.1
#=GS A0A6M8U6R6_9GAMM/2-127 AC A0A6M8U6R6.1
#=GS C0AZL9_9GAMM/402-531 AC C0AZL9.1
#=GS A0A379A9K0_ENTAG/2-103 AC A0A379A9K0.1
#=GS W1DJ08_KLEPN/2-61 AC W1DJ08.1
#=GS A0A0F7H9S5_SERFO/2-129 AC A0A0F7H9S5.1
#=GS A0A2T0VPU0_9GAMM/2-128 AC A0A2T0VPU0.1
#=GS PANZ_SALTY/2-125 AC Q7CPJ9.1
#=GS A0A3N9TZ15_9GAMM/6-126 AC A0A3N9TZ15.1
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A0A7D5IHV3_9PSED/2-129 .....................................................................p-VIVERPSPASAQDL.I...D.L.A.K..I..Yrdap.........dwllpP.Y.A.D..G..E....A....L....I..Q.A..N......L..N..S...G....R..L...L.A..G...R...F..N.D..R.L...LG.....A..A......L....L......E......R......G...........E..D..........C.....W........R......L.SHLC..VRAIT.......RNRGV.ARRL...L....D...E....A..S..R...M..A..-..-..-..-.-...--..--.R.EA.GK..P.L.HLA..AP.EGQLEARAL..AARRG---lpl....................................
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A0A1Q5MZM9_9ACTN/85-154 .......................................................vaaqlgpgrvkellt---------------.-...-.-.-.-..-..-..................-.-.-.-..-..-....-....-....-..-.-..-......-..-..-...-....-..-...-.-..-...-...-..-.-..-.-...--.....-..-......-....-......-......-......-...........-..G..........A.....L........E......I.DELA..VRPYA.......RGRGT.GRDL...L....T...E....I..T..A...D..A..P..D..R..R.A...WL..LT.S.RL.--..-.-.---..--.---------..--------atdtvatyrrlg...........................
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K8WH96_9GAMM/2-131 ......................................................................RLTITPLSDLTNQHI.L...D.L.S.K..I..W..................P.N.H.S..Q..E....H....L....E..Q.W..L......K..S..G...G....N..I...Y.A..A...S...F..N.G..R.L...LG.....A..A......K....V......R......I......E...........Q..Q..........Q.....G........M......I.SDFF..VREVT.......RRRGV.GLYL...V....E...E....I..C..R...Q..N..S..H..I..N.N...WN..MN.L.QN.IS..D.E.NKT..IM.VLFLSSCGFhvAPNSHKW-e......................................
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A0A2D2MCI6_9PSED/2-127 .....................................................................p-VVVEAVRTPSQQDR.L...D.L.A.K..I..Yadap.........adlfaP.G.E.T..A..E....A....W....L..A.A..A......L..A..D...G....S..L...I.A..A...R...F..N.D..R.L...LG.....A..A......R....L......T......R......Q...........H..D..........A.....W........R......L.SHLC..VRSVT.......RRRGV.GLRL...V....S...E....A..Q..R...M..A..R..E..A..G.-...--..--.-.--.--..-.-.---..--.---------..--------qtlrlqattkcaaiqalasqldl................
A0A484ZBU7_9ENTR/2-125 ......................................................................KLTIVRLVTFSDQDH.I...D.L.G.K..I..W..................P.E.Y.S..P..S....S....L....D..-.-..V......D..E..N...H....R..I...Y.A..A...R...F..N.E..R.L...LA.....A..V......R....V......T......L......S...........G..T..........Q.....G........A......L.DSLR..VRDVT.......RRRGV.GQYL...I....E...E....V..M..R...D..N..P..S..V..D.A...WW..MA.D.VG.VE..-.-.DRG..VM.AAFMQALGF..TAQTNGWE.......................................
A0A2V1HI16_9GAMM/2-115 .....................................................................p-ITVHAYTSIADEDIrN...Q.L.E.R..L..Ydtsp..........efsdG.Q.D.A..I..D....Q....L....E..H.N..L......A..Q..Y...T....L..L...Y.T..A...E...F..N.S..R.I...IG.....A..I......W....C......T......G.....gN...........G..D..........E.....R........T......L.QYIV..VHPAN.......RGRGV.AERL...V....A...E....V..C..R...M..E..-..-..-..-.-...--..--.-.--.--..-.-.---..--.---------..--------qdkqvehfipgcga.........................
A0A2J4R4W9_9ENTR/2-125 ......................................................................KLTIIRLQHFSDQDR.I...D.L.G.K..I..W..................P.S.Q.D..L..A....A....L....A..-.-..L......D..E..S...H....R..I...Y.A..A...R...F..N.E..R.L...LA.....A..V......R....V......T......L......N...........G..V..........E.....G........E......L.SALC..VREVT.......RRRGV.GQYL...V....E...E....V..L..R...D..N..P..E..I..G.S...WR..IA.D.TD.VE..-.-.DRG..VM.AAFMQALGF..NAQTGGW-v......................................
A0A368NKI8_9GAMM/2-127 ..........................................................rltalttelldq------------GMR.T...D.L.A.K..L..F..................T.P.E.Q..L..E....Q....L....E..EqA..A......E..A..G...V....H..W...V.L..A...K...F..N.G..R.Y...IG.....A..G......L....F......N......L......-...........-..Q..........A.....A........S......L.IGLT..VRDVT.......RRRGV.GRLL...I....D...Y....C..L..Q...Q..I..K..H..V..A.E...QQ..KL.F.VY.WD..-.R.ADA..DI.AGFMSALAA..TPSDKGW-h......................................
I2B469_SHIBC/2-125 ......................................................................KLTILRLTTLSDQDI.I...D.L.G.K..I..W..................P.E.Y.P..A..D....T....L....Q..-.-..P......D..A..T...H....M..L...Y.A..A...C...F..N.E..R.L...LG.....A..V......R....V......T......V......N...........G..Q..........R.....A........M......L.DSLR..IRDLT.......RRRGV.GLYL...I....E...E....L..L..A...R..H..P..E..I..T.H...WE..MS.D.QG.VE..-.-.DRA..VM.NAFMQALGF..SPCAHGWQ.......................................
A0A6M8U6R6_9GAMM/2-127 ......................................................................KLTIIPLRQFSAQDR.I...D.L.Q.K..I..W..................P.Q.A.D..I..E....K....L....E..R.Q..L......D..D..T...H....R..L...Y.A..A...R...F..N.E..R.L...LG.....A..L......R....M......E......L......S...........G..T..........Q.....G........K......L.YDLT..VREVT.......RRRGV.GQYL...L....E...D....A..L..A...Q..N..P..S..I..T.H...WW..VA.D.DG.SA..-.-.AQE..VI.AAFMQACGF..RAQADGW-v......................................
C0AZL9_9GAMM/402-531 ......................................................................KLTIEKLAQLSEQDR.I...D.L.G.K..I..Wq................dP.R.Y.Q..-..S....A....L....T..N.E..I......N..N..E...N....V..L...F.V..A...R...F..N.E..R.L...LA.....A..C......W....V......K......L......S...........D..K..........K.....A........V......I.TDFM..VREVT.......RRRGV.GHYL...L....T...Q....C..L..S...A..Y..P..D..I..C.H...WQ..AI.S.LS.AE..E.N.GYD..VA.HAFLVHHQF..SPS-----pqsdly.................................
A0A379A9K0_ENTAG/2-103 ......................................................................KLTIQRLTTLTAQDR.I...D.L.G.K..V..W..................P.D.L.E..I..E....Q....L....E..Q.Q..L......D..E..R...H....R..L...Y.A..A...R...F..N.D..R.L...LA.....G..L......Q....L......E......I......A...........G..I..........H.....G........K......I.HRLS..VRDVT.......RRRGV.GQYL...L....E...E....T..I..R...Q..N..G..S..I..A.D...WW..IA.D.--.--..-.-.---..--.---------..--------gw.....................................
W1DJ08_KLEPN/2-61 ......................................................................KLTIIRLQHFSDQDR.I...D.L.G.K..I..W..................P.S.Q.D..L..S....T....L....T..-.-..L......D..E..N...H....R..L...Y.A..A...R...F..N.E..R.L...LG.....A..V......R....V......T......L......R...........G..-..........-.....-........-......-.----..-----.......-----.----...-....-...-....-..-..-...-..-..-..-..-..-.-...--..--.-.--.--..-.-.---..--.---------..--------grr....................................
A0A0F7H9S5_SERFO/2-129 ......................................................................KLTIERLTSLSPQDL.I...D.L.G.K..I..W..................P.H.Q.Q..P..E....Q....W....L..S.W..L......E..E..G...K....A..L...F.A..A...R...F..N.E..R.L...LG.....A..V......K....I......E......I......A...........G..Q..........S.....A........Q......L.HDLL..VREVT.......RRRGV.GLYL...M....E...D....T..Q..R...Q..L..P..Q..V..Q.H...WQ..LD.T.AG.LA..A.R.ERG..EV.GNFMRACGF..QAQGDCWQ.......................................
A0A2T0VPU0_9GAMM/2-128 ........................................................pvtlqqvdqaawea----------DAQIR.L...D.L.A.R..I..Yadap..........aerlP.L.P.V..D..D....F....I....R..D.H..L......T..N..G...H....L..F...S.C..A...R...F..N.D..R.L...LG.....A..V......A....V......K......P......Y...........Q..D..........A.....W........W......L.SNLC..VRRTT.......RRRGV.GSRL...L....A...L....V..S..-...-..-..-..-..-..-.-...--..--.-.--.--..-.-.---..--.---------..--------esahaegrrlyadsahlpvadqmllarl...........
PANZ_SALTY/2-125 ......................................................................KLTILRLEHFSAQDQ.I...D.L.G.K..I..W..................P.E.Y.S..A..S....S....L....S..-.-..V......D..E..T...H....R..I...Y.A..A...R...F..N.E..R.L...LG.....A..V......R....V......T......L......S...........G..T..........Q.....G........A......L.DSLR..VREIT.......RRRGV.GQYL...V....E...E....V..I..R...D..N..P..N..V..S.S...WW..MA.D.VG.VE..-.-.DRS..VM.AAFMQALGF..TAQHDGWE.......................................
A0A3N9TZ15_9GAMM/6-126 ............................................................frvdqdvwda----------DEQVR.I...D.L.T.R..I..Ya...............daP.E.E.R..I..KlppgA....Y....V..T.R..Q......L..E..H...G....F..F...W.A..A...R...F..N.D..R.L...LG.....A..V......A....V......S......P......G...........D..G..........R.....W........R......M.FDLC..VRKTT.......RRRGV.GSRL...L....A...L....I..S..-...-..-..-..-..-..-.-...--..--.-.--.--..-.-.---..--.---------..--------aaanrdgvalsvagsqltladqmllkr............
#=GC seq_cons .......................................................................lhl.hltt.osQDt.h...D.L.s.K..I..a..................P.p.t.s..h..s....t....l....p..t....l......p..p..s...p....p..l...a.u..A...R...F..N.-..R.L...LG.....A..l......t....l......p......h......s...........s..s..........p.....h........p......L.spLs..VRclT.......RRRGV.GphL...l....p...-....s..h..p...t..........................................................................................................
//
