#=GF ID   Parvo_coat
#=GF AC   PF00740.22
#=GF DE   Parvovirus coat protein VP2
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF SE   Pfam-B_436 (release 2.1) & Pfam-B_445 (release 3.0)
#=GF GA   27.00 27.00;
#=GF TC   150.90 28.90;
#=GF NC   20.60 20.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP   Family
#=GF CL   CL0605
#=GF RN   [1]
#=GF RM   9129667
#=GF RT   Tropic determinant for canine parvovirus and feline
#=GF RT   panleukopenia virus functions through the capsid protein VP2. 
#=GF RA   Spitzer AL, Parrish CR, Maxwell IH; 
#=GF RL   J Gen Virol 1997;78:925-928.
#=GF DR   INTERPRO; IPR001403;
#=GF DR   SCOP; 4dpv; fa;
#=GF DC   This family is a subset of the SCOP family
#=GF DR   HOMSTRAD; Parvo_coat2;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This protein, together with VP1 forms a capsomer. Both of these
#=GF CC   proteins are formed from the same transcript using alternative
#=GF CC   splicing.                          As a result, VP1 and VP2
#=GF CC   differ only in the N-terminal region of VP1.     VP2 is involved
#=GF CC   in packaging the viral DNA.
#=GF SQ   17
#=GS CAPSD_HBOC1/156-446       AC Q3YPH4.1
#=GS D3X6X0_CHPV1/346-504      AC D3X6X0.1
#=GS H2ESE5_BTPV1/378-889      AC H2ESE5.1
#=GS Q84367_MUMIP/32-562       AC Q84367.1
#=GS CAPSD_PAVBP/488-646       AC P07297.1
#=GS CAPSD_AAV2S/213-712       AC P03135.2
#=GS CAPSD_ADVG/73-669         AC P24029.3
#=GS A0A501X7X4_9BACT/276-805  AC A0A501X7X4.1
#=GS CAPSD_PAVBP/169-509       AC P07297.1
#=GS CAPSD_HBOC1/497-644       AC Q3YPH4.1
#=GS D3X6W9_CHPV1/485-643      AC D3X6W9.1
#=GS A0A507SHK5_9MOLU/1-220    AC A0A507SHK5.1
#=GS D3X6W9_CHPV1/163-413      AC D3X6W9.1
#=GS CAPSD_PAVHV/237-746       AC Q9PZT0.1
#=GS CAPSD_MUMIP/174-703       AC P03137.3
#=GS H2ESE7_BTPV1/3-514        AC H2ESE7.1
#=GS D3X6X0_CHPV1/24-274       AC D3X6X0.1
CAPSD_HBOC1/156-446                  .................................si-GGGKGSGVGISTGGWVGGSH..FSDKY...VVTKNTRQFITTIQNGHLYK.TE-AIETTNQSG-.....------...---KSQRCVTTPWTYFNFNQYSCHFSPQDWQRLTNEYKRFRPKAMQVKIYNLQIKQILSN.-GADTTY...NNDLTAGVHIFCDGEHAYPNASHPWDEDVMPDLPYKTWKLFQYGYip......ieNELADLD..G.NAAGGNATEKALL.yQMPFF...LLENS.DHQVLRTGES-TEFTFNFDCEWVNN-----.-----.---------------.-----..--------------------------------------.---------..--.-------------.........-----------.----------...--------.----------------------------------------------...-------.........--------.------..---------........-------....................................................---------------------------.-----------..----.........------.............--------...............-------.-------------.......------------erayippglmfnpkvptrrvqyirqngstaastgriqpyskptswmtgpgllsaqrvgpqssdta
D3X6X0_CHPV1/346-504                 kkvkmnegdirnaqidvstatkvqvdtstlyntcp---------------------..-----...--------------------.-------------.....------...------------------------------------------------------------.-------...---------------------------------------------..........-------..-.-------------..-----...-----.------------------------------.-----.---------------.-----..--------------------------------------.---------..--.-------------.........-----------.----------...--------.----------------------------------------------...--RSGYM........sTVSQGGAP.APIVWS..GCVPGMIWD........NRPATYF....................................................DPIWQQFPETDEQFKII-SQLGGIPVK.ESPGHIFVKVT..PKPT.........GAANGLi...........dEYCTFTCT...............VEIEWEL.EPLNTHRWNMRSM.......ISYETTD-----akag.............................................................
H2ESE5_BTPV1/378-889                 .................................te--AEGSGGGIKVKALWTGGTE..FSDTS...IHTSHTRVALLA--DRGTYMpIYRPGETT-----.....------...SVIQPLLGMVTPYSYIDVNSLSAHLTPRDFQQLIDEYGEIRPKSLTIGISGIVVKDVSVN.TTGTAVT...-DSGSGGITVFADEGYDYPYVLGHNQDTLPGHLPGEHYVLPQYAY..........CTRGREV..V.NANKIDIIQDH--..RTDFF...LLEHH.DAXCLNSGDTW-SHTYSFPDLPFRRLTYPS.QHLYA.QHNP------QMKSR.LGVFRsvDQNGDPAWQRLRGSDIGQLPCNYLPGPQANLPTTSDFQkGDSMLPAAIgdPI.TGDRYTVTPLVHQ.........PWSMVHDEYNN.-TGQR-TQSV...VSTVGSVA.Y-MPRKHEE-SYGSPNDAL---TEITTPMRVVQEQADLVSSRLGHT...FMIPSFS.........RKAGSAST.TTYNEPmfPLLPGAVWN........PNPLTYD....................................................CQIWCKVPDTECKFMTQYPLLGGWGMD.TPPPMIFLRIR..RQPGppgpgahtvPGSTLN.............QYVIFHLH...............YSMEFEVrRRKRSRRHNPE--.......------------mpapfpqtwsgkm....................................................
Q84367_MUMIP/32-562                  ...................................GGGSGGGGVGVSTGSYDNQTHyrFLGDGwveITALATRLVHLNMPKSENYC.RIRVHNTTDTSV-.....--KGNM...AKDDAHEQIWTPWSLVDANAWGVWLQPSDWQYICNTMSQLNLVSLDQEIFNVVLKTVTEQ.DLGGQAIkiyNNDLTACMMVAVDSNNILPYTPAANSMETLGFYPWKPTIASPYRYyfc...vdrdLSVTYEN..Q.EGTVEHNVMGTPKgmNSQFF...TIENTqQITLLRTGDEFATGTYYFDT----------.-----.--NSVKLTHTWQTNRqLGQP-..------------------------PL----LSTFPEAD.TD---AGTL..TA.QGSRHGTTQMGVNw.......vSEAIRTRPAQV.GFCQPHNDFE...ASRAGPFA.A--PKVPADITQGVDK-----EANGSVRYSYGKQH-GENWASHGPA...PERYTWDetsfgsgrdTKDGFIQS.APLVVP..PPLNGILTNanp..igtKNDIHFSnvfnsygplt...............................afshpspvypqGQIWDKELDLE--HKPRLHITAPFVCKnNAPGQMLVRLG..P---.........NLTD--.............QYDPNGATlsrivtygtffwkgkLTMRAKL.--RANTTWNPVYQ.......VSAEDNGNSYM-svt..............................................................
CAPSD_PAVBP/488-646                  .........pesdllrlrysasaaegqqnpilena---------------------..-----...--------------------.-------------.....------...------------------------------------------------------------.-------...---------------------------------------------..........-------..-.-------------..-----...-----.------------------------------.-----.---------------.-----..--------------------------------------.---------..--.-------------.........-----------.----------...--------.----------------------------------------------...-ARHTFTrea..rtklITGSNGAD.GDYKEW..WMLPNQMWD........SAPISRY....................................................NPIWVKVPRVN--RKTLLDTQDGSIPMsHPPGTIFIKLAriPVPG.........NGDSFL............nIYVTGQVS...............CEVVWEV.EKRGTKNWRPEYM.......HS----------atnmsvdayt.......................................................
CAPSD_AAV2S/213-712                  ...................................DNNEGADGVGNSSGNWHCDST..WMGDR...VITTSTRTWALPTYNNHLYK.QISSQSGA-----.....------...SNDNHYFGYSTPWGYFDFNRFHCHFSPRDWQRLINNNWGFRPKRLNFKLFNIQVKEVTQN.DGTTTIA...-NNLTSTVQVFTDSEYQLPYVLGSAHQGCLPPFPADVFMVPQYGY..........LTLNN-G..S.QAVG---------..RSSFY...CLEYF.PSQMLRTGNNF-TFSYTFEDVPFHSSYAHS.QSLDR.LMNPLIDQYLYYLSR.TNTPSgtTTQSRLQFSQAGASDIRDQSRNWLPGPCYRQQRVSKTS.ADNNNS---..--.EYSWTGATKYHLN.........GRDSLVNPGPA.MASHKDDEEK...FFPQSGVL.IFGKQGSEKTNVDIEKVMITDEEEIRTTNPVATEQYGSVSTNLQRG...-------.........--NRQAAT.ADVNTQ..GVLPGMVWQ........DRDVYLQ....................................................GPIWAKIPHTDGHFHPS-PLMGGFGLK.HPPPQILIKNT..PVPA.........NPSTTFsaakf...asfitQYSTGQVS...............VEIEWEL.QKENSKRWNPE--.......IQYTSNYNKSV-nvdf.............................................................
CAPSD_ADVG/73-669                    ...................................GGGGGGGGVGNSTGGFNNTTEfkVINNEv.yITCHATRMVHINQADTDEYL.IFNAGRTTDTKTH.....QQKLNLeffVYDDFHQQVMTPWYIVDSNAWGVWMSPKDFQQMKTLCSEISLVTLEQEIDNVTIKTVTET.NQGNASTkqfNNDLTASLQVALDTNNILPYTPAAPLGETLGFVPWRATKPTQYRYyhpcyiynryPNIQKVA..T.ETLTWDAVQDDYLsvDEQYFnfiTIENNiPINILRTGDNFHTGLYEFNS----------.-----.--KPCKLTLSYQSTRcLGLP-..------------------------PLCKPKTDTTHKVT.SKENGADLI..YI.QGQDN--TRLGHFwgeergkknAEMNRIRPYNI.GYQYPEWIIP...AGLQGSYF.AGGPRQWSDTTKGAGTHSQHLQQNFSTRYIYDRNHGGDNEVDLLDGipiHERSNYYsd.....neIEQHTAKQ.PKLRTP..PIHHSKIDSweeegwpaASGTHFEdeviyldyfnfsgeqelnfphevlddaaqmkkllnsyqptvaqdnvgpvypwGQIWDKKPHMD--HKPSMNNNAPFVCKnNPPGQLFVKLT..E---.........NLTDTF.............NYDENP-Driktyg..yftwrgkLVLKGKL.--SQVTCWNPVKReligepgVFTKDKYHKQIP.................................................................
A0A501X7X4_9BACT/276-805             ................................ees---GAGGGALPGPAVWSQGAT..FGEET...VTCFMTRRCYLPFNEDPVYK.PITIQGKHMLRVHdgnlwNSERNL...ELDHPVLGYQTPWHYPDLNSLNLYFSPLEFQHLLEQYSEIAPKSWEVIVSDIVVKDVATQ.NQTTHVT...-DSPTGGLAIFADSSYRFPYVLGTGQNTLPSDIPTEVYLLPQYAY..........LTTGSIQnrH.SGRATDQVTVPNE..ETDFY...VLEHS.TFGIYKTGDFF-THSYTFPTLTPKHLTGSS.QHFFL.MENP------LYGCR.YDILE..EAGTRARWRHINKDEYGIKPQNFLPGPM--TGTHLATQ.GE--NAGKT..EL.QRVLTGTAVGRTP.........ATRWSFRPGPV.SQPYAHAPADdptKDVPDINVdAIAHGYHEPIGQDSDGVLL-----QQGRLPNDREQ-----AKQLSG...IDTQYYPv......tsLGQSFANTrGSGSGR..PLLPGSVWN........ERSLHYE....................................................TQIWAKIPICDRSFMADSPMLGGWGCV.SPPPMLFFKMI..PTPA.........PLGTNVqhdaeskeggalhQYAVFNLT...............VKMVWHVkKRGPGSRWNPQPA.......VYP---------ptgrgth..........................................................
CAPSD_PAVBP/169-509                  ...................................GGGRGGSGVGYSTGGWTGGTI..FSENI...VVTKNTRQFICDIKNGHLYK.S-EVLNTGDTAH-.....------...----RQYAITTPWSYFNFNQYSSHFSPNDWQHLVNDYERFRPKAMIVRVYNLQIKQIMTD.GAMGTVY...NNDLTAGMHIFCDGDHRYPYVQHPWDDQCMPELPNSIWELPQYAYip......apISVVDNN..TtNTVEEHLLK----..GVPLY...MLENS.DHEVLRNGRIY-RIYIQLWRLRMDRKQHHI.QHASDdVQSTGQKQKNLLIQR.TKQP-..---NKQRFQNA-----ALRTSNWMSGPGI-ARGTHNAT.LQTQSAGAL..-V.TMVTNGADVSGVR.........AVRVGYSTDPIyGGQQPESDLL...RLRYSASA.AEG-------------------------------------------...-------.........--------.------..---------........-------....................................................---------------------------.-----------..----.........------.............--------...............-------.-------------.......------------qqnpi............................................................
CAPSD_HBOC1/497-644                  nngniianpslsmlrdqllykgnqttynlvgdiwm---------------------..-----...--------------------.-------------.....------...------------------------------------------------------------.-------...---------------------------------------------..........-------..-.-------------..-----...-----.------------------------------.-----.---------------.-----..--------------------------------------.---------..--.-------------.........-----------.----------...--------.----------------------------------------------...-------.........--------.------..--FPNQVWD........RFPITRE....................................................NPIWCKKPRAD-KHTIMDPFDGSIAMD.HPPGTIFIKMA..KIPVpt.....asNADSYL............nIYCTGQVS...............CEIVWEV.ERYATKNWRPERR.......------------htalgmslggesnytptyh..............................................
D3X6W9_CHPV1/485-643                 kkvkmnegdirnaqidvstatkvqvdtstlyntcp---------------------..-----...--------------------.-------------.....------...------------------------------------------------------------.-------...---------------------------------------------..........-------..-.-------------..-----...-----.------------------------------.-----.---------------.-----..--------------------------------------.---------..--.-------------.........-----------.----------...--------.----------------------------------------------...--RSGYM........sTVSQGGAP.APIVWS..GCVPGMIWD........NRPATYF....................................................DPIWQQFPETDEQFKII-SQLGGIPVK.ESPGHIFVKVT..PKPT.........GAANGLi...........dEYCTFTCT...............VEIEWEL.EPLNTHRWNMRSM.......ISYETTD-----akag.............................................................
A0A507SHK5_9MOLU/1-220               ...................................---------------------..-----...--------------------.-------------.....------...-----------------------------------TMSELHLVSFEQEIFNVVLKTVSESaTQPPTKV..yNNDLTASLMVALDSNNTMPFTPAAMRSETLGFYPWKPTIPTPWRYyfq...wdrtLIPSHTG..T.SGTPTNIYHGTDP.dDVQFY...TIENSvPVHLLRTGDEFATGTFFFDC----------.-----.--KPCRLTHTWQTNRaLGLP-..------------------------PF----LNSLPQAE.GGTNF-GYI..GVqQDKRRGVTQMGNTn......yiTEATIMRPAEV.GYSAPYYSFE...ASTQG---.----------------------------------------------...-------.........--------.------..---------........-------....................................................---------------------------.-----------..----.........------.............--------...............-------.-------------.......------------.................................................................
D3X6W9_CHPV1/163-413                 ..................................v-GGGGGGGIGHSTGNWNCDTI..WAENT...CKTYASRHCVCLMRDMDQYK.AIGNANGQ-----.....-HGLDT...ENQTQYFGFSTPWNYIDFNQYSVHFSPRDWQQLVNNYSRWRPRAVHVKIFNLQVIQKTVT.DSGTQYS...-NDLTGTIQIFADQEGRYPRLLYPNQTTLMGPFPSNIYYLPQYAY..........MTSMF-N..S.GGPTVSSWWGFPT.rESAFY...CLDES.PSQMLRTGNEWE-TTFIFPSSTQWCSNKIStVSITQ.RQNPLYDT-------.-----..--------------------------------------.---------..--.-------------.........-----------.----------...--------.----------------------------------------------...-------.........--------.------..---------........-------....................................................---------------------------.-----------..----.........------.............--------...............-------.-------------.......------------wnvngrg..........................................................
CAPSD_PAVHV/237-746                  ...................................STGAGGGGSNPVKSMWSEGAT..FSANS...VTCTFSRQFLIPYDPEHHYK.VFSPAASSCHNAS.....GKEAKV...CTISPIMGYSTPWRYLDFNALNLFFSPLEFQHLIENYGSIAPDALTVTISEIAVKDVTDK.TGGGVQV...TDSTTGRLSMLVDHEYKYPYVLGQGQDTLAPELPIWVYFPPQYAY..........LTVGDVN..T.QGISGDSKKLASE..ESAFY...VLEHS.SFQLLGTGGT-ATMSYKFPPVPPENLEGCS.QHFYE.MYNP------LYGSR.LGVPD..TLGGDPKFRSLTHEDHAIQPQNFMPGPL--VNSVSTKE.GDSSNTGAG..KAlTGLSTGTSQ----.........NTRISLRPGPV.SQPYHHWDTD...KYVPGINA.I----SHGQTTYGNAEDKE--YQQGVGRFPNEKEQ-----LKQLQG...LNMHTYF.........PNKGTQQY.TDQIER..PLMVGSVWN........RRALHYE....................................................SQLWSKIPNLDDSFKTQFAALGGWGLH.QPPPQIFLKIL..PQSGpigg.iksmGITTLV.............QYAVGIMT...............VTMTFKLgPRKATGRWNPQPG.......VYP-PHAAGHLP.................................................................
CAPSD_MUMIP/174-703                  ...................................GGGSGGGGVGVSTGSYDNQTHyrFLGDGwveITALATRLVHLNMPKSENYC.RIRVHNTTDTSV-.....--KGNM...AKDDAHEQIWTPWSLVDANAWGVWLQPSDWQYICNTMSQLNLVSLDQEIFNVVLKTVTEQ.DLGGQAIkiyNNDLTACMMVAVDSNNILPYTPAANSMETLGFYPWKPTIASPYRYyfc...vdrdLSVTYEN..Q.EGTVEHNVMGTPKgmNSQFF...TIENTqQITLLRTGDEFATGTYYFDT----------.-----.--NSVKLTHTWQTNRqLGQP-..------------------------PL----LSTFPEAD.TD---AGTL..TA.QGSRHGTTQMGVNw.......vSEAIRTRPAQV.GFCQPHNDFE...ASRAGPFA.A--PKVPADITQGVDK-----EANGSVRYSYGKQH-GENWASHGPA...PERYTWDetsfgsgrdTKDGFIQS.APLVVP..PPLNGILTNanp..igtKNDIHFSnvfnsygplt...............................afshpspvypqGQIWDKELDLE--HKPRLHITAPFVCKnNAPGQMLVRLG..P---.........NLTD--.............QYDPNGATlsrivtygtffwkgkLTMRAKL.--RANTTWNPVYQ.......VSAEDNGNSYM-sv...............................................................
H2ESE7_BTPV1/3-514                   .................................te--AEGSGGGIKVKALWTGGTE..FSDTS...IHTSHTRVALLA--DRGTYMpIYRPGETT-----.....------...SVIQPLLGMVTPYSYIDVNSLSAHLTPRDFQQLIDEYGEIRPKSLTIGISGIVVKDVSVN.TTGTAVT...-DSGSGGITVFADEGYDYPYVLGHNQDTLPGHLPGEHYVLPQYAY..........CTRGREV..V.NANKIDIIQDH--..RTDFF...LLEHH.DAXCLNSGDTW-SHTYSFPDLPFRRLTYPS.QHLYA.QHNP------QMKSR.LGVFRsvDQNGDPAWQRLRGSDIGQLPCNYLPGPQANLPTTSDFQkGDSMLPAAIgdPI.TGDRYTVTPLVHQ.........PWSMVHDEYNN.-TGQR-TQSV...VSTVGSVA.Y-MPRKHEE-SYGSPNDAL---TEITTPMRVVQEQADLVSSRLGHT...FMIPSFS.........RKAGSAST.TTYNEPmfPLLPGAVWN........PNPLTYD....................................................CQIWCKVPDTECKFMTQYPLLGGWGMD.TPPPMIFLRIR..RQPGppgpgahtvPGSTLN.............QYVIFHLH...............YSMEFEVrRRKRSRRHNPE--.......------------mpapfpqtwsgkm....................................................
D3X6X0_CHPV1/24-274                  ..................................v-GGGGGGGIGHSTGNWNCDTI..WAENT...CKTYASRHCVCLMRDMDQYK.AIGNANGQ-----.....-HGLDT...ENQTQYFGFSTPWNYIDFNQYSVHFSPRDWQQLVNNYSRWRPRAVHVKIFNLQVIQKTVT.DSGTQYS...-NDLTGTIQIFADQEGRYPRLLYPNQTTLMGPFPSNIYYLPQYAY..........MTSMF-N..S.GGPTVSSWWGFPT.rESAFY...CLDES.PSQMLRTGNEWE-TTFIFPSSTQWCSNKIStVSITQ.RQNPLYDT-------.-----..--------------------------------------.---------..--.-------------.........-----------.----------...--------.----------------------------------------------...-------.........--------.------..---------........-------....................................................---------------------------.-----------..----.........------.............--------...............-------.-------------.......------------wnvngrg..........................................................
#=GC seq_cons                        .....................................stuuuGhh.spu.astts...a.tp....hhs..oR.hhh...p.t.Yh...ts.tst......................p...th.TPathhshNthshahpP.-aQ.lhpphtphp.huhp.tl.sl.lKpls.p.stssthh....sshTush.lhsDpp..hPhs.t..ptph.s.hP.p.hh.s.YtY..........hs....s..t.pu...p.h.......pstFa...hlEpp.s.thLpoGspa.phoa.Fss...................ps...................................................................................................................................................................................................tt..t..s.........hss.lhs.........tshph.....................................................s.IWtp..ph-..ah......ushsh..psPs.hhl+hh...............shss................Ys...hp...............hph.hcl....tsppap.........................s..............................................................
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