#=GF ID PepSY_2
#=GF AC PF13670.10
#=GF DE Peptidase propeptide and YPEB domain
#=GF AU Coggill P;0000-0001-5731-1588
#=GF SE Jackhmmer:C6QGP5
#=GF GA 24.30 24.30;
#=GF TC 24.30 24.30;
#=GF NC 24.20 24.20;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP Domain
#=GF CL CL0320
#=GF RN [1]
#=GF RM 7674922
#=GF RT Evolutionary families of metallopeptidases.
#=GF RA Rawlings ND, Barrett AJ;
#=GF RL Meth Enzymol 1995;248:183-228.
#=GF RN [2]
#=GF RM 15124630
#=GF RT The PepSY domain: a regulator of peptidase activity in the
#=GF RT microbial environment?.
#=GF RA Yeats C, Rawlings ND, Bateman A;
#=GF RL Trends Biochem Sci 2004;29:169-172.
#=GF RN [3]
#=GF RM 15583150
#=GF RT Identification of residues in the Pseudomonas aeruginosa
#=GF RT elastase propeptide required for chaperone and secretion
#=GF RT activities.
#=GF RA McIver KS, Kessler E, Ohman DE;
#=GF RL Microbiology 2004;150:3969-3977.
#=GF DR INTERPRO; IPR025711;
#=GF DR PROSITE; PDOC00129;
#=GF DC This Prosite motif covers only the active site.
#=GF DR MEROPS; M4;
#=GF DC This is family M4 in the peptidase classification.
#=GF DR SCOP; 1qf2; fa;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC This region is likely to have a protease inhibitory function
#=GF CC (personal obs:C Yeats). The name is derived from Peptidase &
#=GF CC Bacillus subtilis YPEB.
#=GF SQ 1638
#=GS A0A3F2U2D1_9HYPH/6-90 AC A0A3F2U2D1.1
#=GS D8JRG1_HYPDA/7-86 AC D8JRG1.1
#=GS A0A7W7Z4Q8_9BRAD/4-84 AC A0A7W7Z4Q8.1
#=GS A0A427DLT8_9PSED/8-86 AC A0A427DLT8.1
#=GS F3KE31_9GAMM/5-88 AC F3KE31.1
#=GS A0A853JAM0_9GAMM/6-83 AC A0A853JAM0.1
#=GS A0A0D8CG98_9PROT/1-81 AC A0A0D8CG98.1
#=GS A0A845M4T1_9RHOB/3-91 AC A0A845M4T1.1
#=GS G7UVJ2_PSEUP/4-83 AC G7UVJ2.1
#=GS A0A0J0YT66_9NEIS/4-86 AC A0A0J0YT66.1
#=GS A4EIN3_9RHOB/3-75 AC A4EIN3.1
#=GS J1JXE5_9HYPH/8-94 AC J1JXE5.1
#=GS A0A0Q8FC48_9GAMM/93-150 AC A0A0Q8FC48.1
#=GS I4W100_9GAMM/25-106 AC I4W100.1
#=GS A0A238J8M1_9RHOB/7-86 AC A0A238J8M1.1
#=GS A0A2M9P993_9RHOB/4-83 AC A0A2M9P993.1
#=GS A0A4R3UJ79_PELSC/3-87 AC A0A4R3UJ79.1
#=GS A0A4Q5VEK6_9GAMM/2-85 AC A0A4Q5VEK6.1
#=GS A0A154QWM7_9GAMM/104-165 AC A0A154QWM7.1
#=GS A0A1N6WRN9_9GAMM/3-86 AC A0A1N6WRN9.1
#=GS M1FJV1_9GAMM/5-86 AC M1FJV1.1
#=GS A0A285CLJ4_9RHOB/5-86 AC A0A285CLJ4.1
#=GS A0A1Y5S803_9RHOB/5-87 AC A0A1Y5S803.1
#=GS A0A0Q4XTA1_9HYPH/10-88 AC A0A0Q4XTA1.1
#=GS C6WZ52_METML/1-83 AC C6WZ52.1
#=GS A0A7Y6NJX9_9BURK/7-90 AC A0A7Y6NJX9.1
#=GS A0A421BRV8_9RHOB/6-83 AC A0A421BRV8.1
#=GS A0A0L6CZG7_9RHOB/6-93 AC A0A0L6CZG7.1
#=GS Q92X76_RHIME/5-99 AC Q92X76.1
#=GS A1TTN9_ACIAC/143-208 AC A1TTN9.1
#=GS A0A4P6VW97_9GAMM/6-87 AC A0A4P6VW97.1
#=GS A0A1V3NYC5_9GAMM/5-107 AC A0A1V3NYC5.1
#=GS A0A0Q6B9N1_9PROT/6-88 AC A0A0Q6B9N1.1
#=GS A0A255XW23_9PROT/4-84 AC A0A255XW23.1
#=GS A0A1I4RWC0_9HYPH/5-91 AC A0A1I4RWC0.1
#=GS A0A285S089_9RHOB/7-88 AC A0A285S089.1
#=GS L1NK69_9NEIS/3-91 AC L1NK69.1
#=GS A0A2T6AWJ5_9RHOB/5-86 AC A0A2T6AWJ5.1
#=GS A0A845B8J5_9SPHN/8-91 AC A0A845B8J5.1
#=GS A0A1E3VZI9_9HYPH/4-86 AC A0A1E3VZI9.1
#=GS A0A1G7F2T4_9BURK/8-92 AC A0A1G7F2T4.1
#=GS A0A8J2ZNU8_9RHOB/5-86 AC A0A8J2ZNU8.1
#=GS A0A286GK28_9PROT/7-88 AC A0A286GK28.1
#=GS A0A120CY45_HYPSL/6-92 AC A0A120CY45.1
#=GS A0A0R0A8J4_9GAMM/8-91 AC A0A0R0A8J4.1
#=GS A0A8H2PKU2_9GAMM/5-91 AC A0A8H2PKU2.1
#=GS E6WXH7_PSEUU/90-157 AC E6WXH7.1
#=GS A0A0Q6S852_9HYPH/5-87 AC A0A0Q6S852.1
#=GS A0A6M1UL96_9BACT/28-111 AC A0A6M1UL96.1
#=GS A0A238XES8_9RHOB/2-78 AC A0A238XES8.1
#=GS I8U786_9ALTE/4-83 AC I8U786.1
#=GS A0A6M4H9I3_9PROT/2-83 AC A0A6M4H9I3.1
#=GS A0A7G9RQC8_9BURK/6-90 AC A0A7G9RQC8.1
#=GS A0A4R6P4A4_9GAMM/6-91 AC A0A4R6P4A4.1
#=GS A0A1P8UNC3_9RHOB/5-86 AC A0A1P8UNC3.1
#=GS A0A0W1A1N3_9GAMM/9-86 AC A0A0W1A1N3.1
#=GS A0A1D9MBF6_9RHOB/5-87 AC A0A1D9MBF6.1
#=GS A0A844D407_9RHOB/2-80 AC A0A844D407.1
#=GS Q0BXA5_HYPNA/4-84 AC Q0BXA5.1
#=GS A0A4V2JFY2_9BURK/5-87 AC A0A4V2JFY2.1
#=GS A0A0A0E8T1_9RHOB/7-82 AC A0A0A0E8T1.1
#=GS A0A368YFE0_9RHOB/5-86 AC A0A368YFE0.1
#=GS A0A143HLL4_9GAMM/10-88 AC A0A143HLL4.1
#=GS A0A021X2B8_9HYPH/17-101 AC A0A021X2B8.1
#=GS A0A1M7IMA9_9RHOB/5-86 AC A0A1M7IMA9.1
#=GS A0A7W6CUV7_9HYPH/6-84 AC A0A7W6CUV7.1
#=GS A0A175Y1T8_9SPHN/8-91 AC A0A175Y1T8.1
#=GS A0A091B898_9PROT/30-115 AC A0A091B898.1
#=GS A0A1I1QXJ2_9RHOB/5-87 AC A0A1I1QXJ2.1
#=GS A0A1U7D8T0_9RHOB/4-78 AC A0A1U7D8T0.1
#=GS A0A371XEI1_9HYPH/5-86 AC A0A371XEI1.1
#=GS A0KFP9_AERHH/3-86 AC A0KFP9.1
#=GS K2JLQ7_9GAMM/4-100 AC K2JLQ7.1
#=GS A0A7W5Z760_9HYPH/6-89 AC A0A7W5Z760.1
#=GS A0A6P1T083_9RHOB/3-84 AC A0A6P1T083.1
#=GS A0A562TBR4_9HYPH/12-89 AC A0A562TBR4.1
#=GS A0A2V2LE08_9RHOB/5-86 AC A0A2V2LE08.1
#=GS A0A0Q4XV74_9HYPH/6-85 AC A0A0Q4XV74.1
#=GS A0A2W2BZI3_9HYPH/5-86 AC A0A2W2BZI3.1
#=GS Q5F6R1_NEIG1/3-91 AC Q5F6R1.1
#=GS A0A317FBX2_9PROT/9-92 AC A0A317FBX2.1
#=GS X7F9X5_9RHOB/4-86 AC X7F9X5.1
#=GS A0A7W9FNR9_9HYPH/5-88 AC A0A7W9FNR9.1
#=GS A0A0S2DNW9_LYSEN/18-99 AC A0A0S2DNW9.1
#=GS A0A0A1YQZ6_9PSED/2-85 AC A0A0A1YQZ6.1
#=GS A0A0D1M2H0_BRAEL/6-90 AC A0A0D1M2H0.1
#=GS A0A1G5PUU5_9GAMM/7-95 AC A0A1G5PUU5.1
#=GS A0A2S0URE2_9RHOB/2-83 AC A0A2S0URE2.1
#=GS A0A0S2DYC6_LYSAN/4-83 AC A0A0S2DYC6.1
#=GS A0A0T5P465_9RHOB/8-95 AC A0A0T5P465.1
#=GS A0A285T217_9RHOB/3-82 AC A0A285T217.1
#=GS A0A091BK35_9GAMM/83-139 AC A0A091BK35.1
#=GS A0A512IJ28_9HYPH/7-85 AC A0A512IJ28.1
#=GS A0A5B8RPX2_9BURK/10-90 AC A0A5B8RPX2.1
#=GS A0A3L7A509_9HYPH/11-92 AC A0A3L7A509.1
#=GS A0A2T4J4Y1_9RHOB/31-111 AC A0A2T4J4Y1.1
#=GS C1DBC8_LARHH/5-89 AC C1DBC8.1
#=GS A0A1V2H4V8_9PROT/6-92 AC A0A1V2H4V8.1
#=GS A0A1Y6CMK0_9HYPH/6-93 AC A0A1Y6CMK0.1
#=GS A0A8J8AX68_9GAMM/82-143 AC A0A8J8AX68.1
#=GS A0A520EWU1_SPHSX/1-50 AC A0A520EWU1.1
#=GS A0A417XS19_9ACTN/17-103 AC A0A417XS19.1
#=GS A0A0G3XCS9_9SPHN/10-93 AC A0A0G3XCS9.1
#=GS A0A7X6EM75_9PSED/4-42 AC A0A7X6EM75.1
#=GS A0A6L6JIV0_9RHOB/98-173 AC A0A6L6JIV0.1
#=GS L2F8K8_9GAMM/8-105 AC L2F8K8.1
#=GS Q63KA4_BURPS/1-69 AC Q63KA4.1
#=GS H0Q2Y2_9RHOO/5-88 AC H0Q2Y2.1
#=GS A0A069P5U2_9BURK/3-85 AC A0A069P5U2.1
#=GS A0A1M6XM87_9RHOB/3-80 AC A0A1M6XM87.1
#=GS A0A2U2CR11_9RHOB/7-77 AC A0A2U2CR11.1
#=GS A0A8J2ZA38_9PROT/9-92 AC A0A8J2ZA38.1
#=GS A0A7H0GNX5_9BURK/6-89 AC A0A7H0GNX5.1
#=GS A0A0D0R4C4_9GAMM/6-87 AC A0A0D0R4C4.1
#=GS A0A0L6CQ34_9RHOB/5-81 AC A0A0L6CQ34.1
#=GS A0A2T4JLW5_9RHOB/7-93 AC A0A2T4JLW5.1
#=GS A0A0Q5W9H2_9HYPH/7-93 AC A0A0Q5W9H2.1
#=GS Q8PEF5_XANCP/2-82 AC Q8PEF5.1
#=GS A0A3A5MMD5_9MICO/109-196 AC A0A3A5MMD5.1
#=GS A0A160MYV6_9GAMM/78-142 AC A0A160MYV6.1
#=GS A0A085U0S5_9RHOB/89-153 AC A0A085U0S5.1
#=GS A0A7W8HH08_9BURK/9-90 AC A0A7W8HH08.1
#=GS A0A518GD12_9BACT/87-152 AC A0A518GD12.1
#=GS A0A840Y4W9_9PROT/12-89 AC A0A840Y4W9.1
#=GS A0A3F2UHL3_9HYPH/5-85 AC A0A3F2UHL3.1
#=GS A0A5C8WPW9_9HYPH/4-82 AC A0A5C8WPW9.1
#=GS A0A0W0VS72_9GAMM/83-145 AC A0A0W0VS72.1
#=GS A0A4S5BJK4_9BURK/92-154 AC A0A4S5BJK4.1
#=GS A0A1M7AV84_9RHOB/6-88 AC A0A1M7AV84.1
#=GS A0A1H2B9K7_9ACTN/76-154 AC A0A1H2B9K7.1
#=GS A0A011PTN0_ACCRE/9-99 AC A0A011PTN0.1
#=GS A0A0Q9EJ17_9GAMM/80-141 AC A0A0Q9EJ17.1
#=GS A0A1I6YZF3_9RHOB/38-115 AC A0A1I6YZF3.1
#=GS A0A2S9KBE5_9BURK/3-85 AC A0A2S9KBE5.1
#=GS A0A418WTG1_9PROT/7-87 AC A0A418WTG1.1
#=GS A0A1M4SH29_9GAMM/6-87 AC A0A1M4SH29.1
#=GS A0A8J7J5Z6_9RHOB/5-86 AC A0A8J7J5Z6.1
#=GS A0A1I4RWV6_9PSED/8-89 AC A0A1I4RWV6.1
#=GS A0A063B4P2_9BURK/8-92 AC A0A063B4P2.1
#=GS A0A0S9MVD3_9BURK/10-94 AC A0A0S9MVD3.1
#=GS A0A512DZ22_9PROT/1-70 AC A0A512DZ22.1
#=GS A0A1G6XI65_9BURK/3-85 AC A0A1G6XI65.1
#=GS A0A1I4E6M9_9PROT/7-99 AC A0A1I4E6M9.1
#=GS A0A0E3Z1L3_9GAMM/5-82 AC A0A0E3Z1L3.1
#=GS A0A1B4V424_9GAMM/2-83 AC A0A1B4V424.1
#=GS A0A1X6ZKY0_9RHOB/5-83 AC A0A1X6ZKY0.1
#=GS A0A1K2HMV8_9BURK/5-89 AC A0A1K2HMV8.1
#=GS H5WP31_9BURK/5-89 AC H5WP31.1
#=GS A0A372EWN2_9RHOB/6-81 AC A0A372EWN2.1
#=GS A0A495RNL8_SPHMI/3-82 AC A0A495RNL8.1
#=GS A0A844W0P8_9RHOB/3-81 AC A0A844W0P8.1
#=GS W7X2Z1_9BURK/18-108 AC W7X2Z1.1
#=GS A0A1V2GY59_9PROT/87-154 AC A0A1V2GY59.1
#=GS A0A840AFR6_9PROT/6-88 AC A0A840AFR6.1
#=GS A0A0Q8KDF5_9HYPH/5-84 AC A0A0Q8KDF5.1
#=GS A0A2K9JLI4_9RHOB/3-80 AC A0A2K9JLI4.1
#=GS A0A5N7MHZ9_9HYPH/5-91 AC A0A5N7MHZ9.1
#=GS A0A1I7I5L5_9BURK/8-96 AC A0A1I7I5L5.1
#=GS A0A3S8U4K8_9RHOB/12-93 AC A0A3S8U4K8.1
#=GS A0A7H0GIC6_9BURK/6-100 AC A0A7H0GIC6.1
#=GS A0A2G3K375_9BURK/2-84 AC A0A2G3K375.1
#=GS A0A1I6A9I4_9RHOB/4-83 AC A0A1I6A9I4.1
#=GS A0A085TX41_9RHOB/4-81 AC A0A085TX41.1
#=GS A0A238KTZ7_9RHOB/5-86 AC A0A238KTZ7.1
#=GS D5RR60_9PROT/13-96 AC D5RR60.1
#=GS A0A4Q8QXQ9_9BRAD/3-75 AC A0A4Q8QXQ9.1
#=GS A0A7X3LR99_9HYPH/6-92 AC A0A7X3LR99.1
#=GS A0A0Q8KAU0_9HYPH/4-87 AC A0A0Q8KAU0.1
#=GS A0A1I1QL18_9RHOB/5-86 AC A0A1I1QL18.1
#=GS A0A401Y293_9ACTN/9-99 AC A0A401Y293.1
#=GS A0A516SKM4_9BURK/3-85 AC A0A516SKM4.1
#=GS A0A0L0MFN1_9BURK/3-85 AC A0A0L0MFN1.1
#=GS A0A2W7IWG8_9PROT/6-87 AC A0A2W7IWG8.1
#=GS A0A2K9MHP8_9RHOB/5-86 AC A0A2K9MHP8.1
#=GS A0A0Q6Z2J5_9BRAD/3-82 AC A0A0Q6Z2J5.1
#=GS A0A1I0QKV4_9RHOB/5-87 AC A0A1I0QKV4.1
#=GS A9BN31_DELAS/94-175 AC A9BN31.1
#=GS A0A1P8UNC5_9RHOB/5-87 AC A0A1P8UNC5.1
#=GS A0A3M6QF03_9BURK/77-141 AC A0A3M6QF03.1
#=GS A0A1G5BQC9_9RHOB/3-80 AC A0A1G5BQC9.1
#=GS A0A1G5KB62_9HYPH/4-91 AC A0A1G5KB62.1
#=GS A0A1Q8YBB8_9BURK/11-90 AC A0A1Q8YBB8.1
#=GS A0A2U2CEQ1_9RHOB/3-77 AC A0A2U2CEQ1.1
#=GS J0U6P3_9BURK/151-212 AC J0U6P3.1
#=GS A0A1E5Q8V8_9PROT/10-92 AC A0A1E5Q8V8.1
#=GS Q89WT0_BRADU/29-111 AC Q89WT0.1
#=GS A0A6B3SS91_9BURK/6-88 AC A0A6B3SS91.1
#=GS A4YYE7_BRASO/4-89 AC A4YYE7.1
#=GS A0A657LYM4_9HYPH/31-106 AC A0A657LYM4.1
#=GS A0A0B4EC79_9RHOB/5-80 AC A0A0B4EC79.1
#=GS A0A4Y4D0K0_ZOORA/34-116 AC A0A4Y4D0K0.1
#=GS A0A844H5A9_9RHOB/6-88 AC A0A844H5A9.1
#=GS A0A1T5KRH0_9GAMM/9-89 AC A0A1T5KRH0.1
#=GS A0A0L1JJX8_9RHOB/2-81 AC A0A0L1JJX8.1
#=GS A0A1G6PC67_9BURK/150-212 AC A0A1G6PC67.1
#=GS A0A0D6JGH3_9HYPH/5-88 AC A0A0D6JGH3.1
#=GS A0A6N8A4M8_9HYPH/10-89 AC A0A6N8A4M8.1
#=GS A0A6S6Y8T8_9PROT/5-89 AC A0A6S6Y8T8.1
#=GS A0A6C0TW42_9PSED/3-84 AC A0A6C0TW42.1
#=GS A0A841HUL9_9GAMM/4-89 AC A0A841HUL9.1
#=GS A0A6H9Y594_9PROT/17-98 AC A0A6H9Y594.1
#=GS A0A0Q4GW68_9BURK/8-95 AC A0A0Q4GW68.1
#=GS A0A3S8U3I8_9RHOB/5-86 AC A0A3S8U3I8.1
#=GS A0A0C4WJD3_9GAMM/2-85 AC A0A0C4WJD3.1
#=GS A0A238JZ43_9RHOB/4-80 AC A0A238JZ43.1
#=GS A0A2T7UVS1_9RHOB/6-82 AC A0A2T7UVS1.1
#=GS A0A3L7AAU4_9HYPH/6-85 AC A0A3L7AAU4.1
#=GS Q2YRI6_BRUA2/4-86 AC Q2YRI6.1
#=GS A0A370X1Y6_9GAMM/20-97 AC A0A370X1Y6.1
#=GS A0A2U2CRR4_9RHOB/5-87 AC A0A2U2CRR4.1
#=GS A0A257HGR5_9HYPH/47-128 AC A0A257HGR5.1
#=GS A0A839HKM5_9BURK/9-89 AC A0A839HKM5.1
#=GS A0A1I7NT24_9HYPH/4-81 AC A0A1I7NT24.1
#=GS A0A1I0YDA8_9RHOB/3-85 AC A0A1I0YDA8.1
#=GS A0A0C4Y1J3_9BURK/13-98 AC A0A0C4Y1J3.1
#=GS A0A1I2Z3Z3_9GAMM/7-86 AC A0A1I2Z3Z3.1
#=GS A0A1H8HWQ6_9RHOB/3-84 AC A0A1H8HWQ6.1
#=GS A0A1G8R3T9_9RHOB/5-86 AC A0A1G8R3T9.1
#=GS A0A127F8E6_STEDE/13-101 AC A0A127F8E6.1
#=GS A0A251XAD3_9GAMM/7-96 AC A0A251XAD3.1
#=GS A0A3T0N768_9RHOB/4-84 AC A0A3T0N768.1
#=GS A0A562LEJ9_9GAMM/3-78 AC A0A562LEJ9.1
#=GS A0A4D7QGC4_9HYPH/23-107 AC A0A4D7QGC4.1
#=GS A0A011UXL3_9HYPH/5-87 AC A0A011UXL3.1
#=GS A0A256FWS1_9HYPH/5-88 AC A0A256FWS1.1
#=GS A0A3N5ZBQ2_9ALTE/25-107 AC A0A3N5ZBQ2.1
#=GS A0A2U2CHA5_9RHOB/4-87 AC A0A2U2CHA5.1
#=GS A0A159Z974_9RHOB/5-86 AC A0A159Z974.1
#=GS A0A1G8RYP8_9RHOB/6-87 AC A0A1G8RYP8.1
#=GS A0A1X7PA23_AZOLI/6-101 AC A0A1X7PA23.1
#=GS I3THL0_TISMK/10-94 AC I3THL0.1
#=GS A0A0Q7PPN5_9GAMM/5-79 AC A0A0Q7PPN5.1
#=GS A0A4Q2R811_9HYPH/4-84 AC A0A4Q2R811.1
#=GS A0A1V3S450_9BURK/3-85 AC A0A1V3S450.1
#=GS A0A0R0BJF7_9GAMM/2-79 AC A0A0R0BJF7.1
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