#=GF ID Peptidase_C42
#=GF AC PF05533.16
#=GF DE Beet yellows virus-type papain-like endopeptidase C42
#=GF AU Studholme DJ;0000-0002-3010-6637
#=GF SE Merops
#=GF GA 25.00 25.00;
#=GF TC 27.50 27.40;
#=GF NC 21.50 23.20;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP Domain
#=GF CL CL0125
#=GF RN [1]
#=GF RM 11711606
#=GF RT Functional specialization and evolution of leader proteinases in
#=GF RT the family Closteroviridae.
#=GF RA Peng CW, Peremyslov VV, Mushegian AR, Dawson WO, Dolja VV;
#=GF RL J Virol 2001;75:12153-12160.
#=GF DR INTERPRO; IPR008749;
#=GF DR MEROPS; C42;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC Members of the Closteroviridae and Potyviridae families of plant
#=GF CC positive-strand RNA viruses encode one or two papain-like leader
#=GF CC proteinases, belonging to Merops peptidase family C42.
#=GF SQ 21
#=GS A0A385L375_9CLOS/413-495 AC A0A385L375.1
#=GS R1AB_BYVU/502-589 AC Q08534.2
#=GS V5IV38_9CLOS/531-618 AC V5IV38.1
#=GS Q49IH3_9CLOS/486-573 AC Q49IH3.1
#=GS Q5G7G7_9CLOS/451-544 AC Q5G7G7.1
#=GS A0A385L375_9CLOS/631-720 AC A0A385L375.1
#=GS A0A385HW54_9CLOS/428-516 AC A0A385HW54.1
#=GS Q8BEP9_9CLOS/485-572 AC Q8BEP9.1
#=GS Q66237_9CLOS/396-485 AC Q66237.1
#=GS A0A385HW49_9CLOS/428-516 AC A0A385HW49.1
#=GS Q0GK55_9CLOS/355-440 AC Q0GK55.1
#=GS A0A088MGX0_9CLOS/329-414 AC A0A088MGX0.1
#=GS C6GFJ7_9CLOS/373-464 AC C6GFJ7.1
#=GS Q66237_9CLOS/889-977 AC Q66237.1
#=GS Q49IH3_9CLOS/760-847 AC Q49IH3.1
#=GS Q8BEP9_9CLOS/754-841 AC Q8BEP9.1
#=GS A0A088MGX0_9CLOS/530-619 AC A0A088MGX0.1
#=GS A0A2U8JH86_9CLOS/517-602 AC A0A2U8JH86.1
#=GS A0A0K1HRG5_9CLOS/430-524 AC A0A0K1HRG5.1
#=GS Q0GK55_9CLOS/559-651 AC Q0GK55.1
#=GS A0A0A0P6V8_9CLOS/367-458 AC A0A0A0P6V8.1
A0A385L375_9CLOS/413-495 .....q-KPAEGFCYIEHLFDVNLHTG.RAF.pFKSAF....SLGAYPKMSQIVDFLSEKISDDLCRSATRGSFN-.GRVFHCHR--------------..---ggdyfylapdvr.......
#=GR A0A385L375_9CLOS/413-495 pAS .............*...................................................................*.........................................
R1AB_BYVU/502-589 .....y-RPGEGLCYLAHAALCCALQK.RTF..REEDF....FVGMYPTKFVFAKRLTEKLGPSALKHPVRGRQVS.RSLFHCDVASAFSSPFYSLPRF..IGG...................
#=GR R1AB_BYVU/502-589 AS .............*...................................................................*.........................................
V5IV38_9CLOS/531-618 ....yq--PGEGLCYLTHAAFCCAHFQ.RTF..KEEDF....YVGVYTTKHIVARKLIEKLGPESLNYHVRGRQTA.RDLFHCDLMSTTSYPFYSLPKF..LGG...................
#=GR V5IV38_9CLOS/531-618 pAS .............*...................................................................*.........................................
Q49IH3_9CLOS/486-573 .....i-NYQDGHCYLAHMRYLCAFYC.RPF..RESDY....ALGSWPTVARLKACVEKNFGVEACGIALRGYYTS.RNVYHCDYDSSYMRGFRNLSGR..VGG...................
#=GR Q49IH3_9CLOS/486-573 pAS .............*...................................................................*.........................................
Q5G7G7_9CLOS/451-544 ....fh--SPNGLCYLNHVWFLCLISG.TSF..LRARKy.fgRLGAFPGVESFFSLLCNFFSYHAVRIQIRGYFTS.TGIFHCDNV-------------..---rgnlfnhryqrlrsarvgg
#=GR Q5G7G7_9CLOS/451-544 pAS .............*...................................................................*.........................................
A0A385L375_9CLOS/631-720 ...pkt---QYGHCYLHYIFECCVGWG.IQF..DASKAi..kALHTLPTLKCLQLYI-KSLGLQEPKF-LRGYFKS.KTLFHCDIDSPTIVSVNAFKGCevIGG...................
#=GR A0A385L375_9CLOS/631-720 pAS .............*...................................................................*.........................................
A0A385HW54_9CLOS/428-516 ...fsa---SKGFCYLNHLWYLCLISG.HSF..SSARGt.flKLGKYPRFSDFIATVGKYFSFPATRVGLMGYFSA.ASTFHCDN--------------..---fkgrvhwgsyrrlrf....
#=GR A0A385HW54_9CLOS/428-516 pAS .............*...................................................................*.........................................
Q8BEP9_9CLOS/485-572 ......ECYPDGLCYMAHMRYLCAFFC.QPF..RESDY....PLGSWPSVARLKALVLKRFGDEALNIGVRGYYVS.RRAFHCDYDSKYARSLMRLAGY..VGG...................
#=GR Q8BEP9_9CLOS/485-572 pAS .............*...................................................................*.........................................
Q66237_9CLOS/396-485 .....a-KVRDGQCYVRHVFDVALYFG.RRA..D---LsvrrALGMYPTVGALKAYLVREYGRDSLKVPMRGTYTF.GSVFHCLSLNLQV-DLRSIPNHhlVGG...................
#=GR Q66237_9CLOS/396-485 pAS .............*...................................................................*.........................................
A0A385HW49_9CLOS/428-516 ...fsa---SKGFCYLNHLWYLCLISG.HSF..SSARGt.flKLGKYPRFSDFIATVGKYFSFPATRVGLMGYFSA.ASTFHCDN--------------..---fkgrvhwgsyrrlrf....
#=GR A0A385HW49_9CLOS/428-516 pAS .............*...................................................................*.........................................
Q0GK55_9CLOS/355-440 ....ps--VADGRCYLAHVFLVAVTLG.VTA..KFWKF...tSLGSFPSLKAFRVRLASVFGPEALDVAFRATI-K.GKLAHCDLSSP-----------..---ltdlpedcivgg.......
#=GR Q0GK55_9CLOS/355-440 pAS .............*...................................................................*.........................................
A0A088MGX0_9CLOS/329-414 ....pd--MQSGMCYLAHVFLVSLTLGvRGR..YKSFL....SLGRYPSVEDFEHRLVSVFGNDALSVAYRGS-SS.GGVFHCDLTQDYA--F------..---vgageligg..........
#=GR A0A088MGX0_9CLOS/329-414 pAS .............*...................................................................*.........................................
C6GFJ7_9CLOS/373-464 ....yh--APRGYCYLNHIFFLSLRAG.CAF..RPAKNy.fkTLGRNPSATDLSARISAYFGFAAASYHIAGRYTG.YNRFHCDNSSRKLYTLEYLRE-..---aavga..............
#=GR C6GFJ7_9CLOS/373-464 pAS .............*...................................................................*.........................................
Q66237_9CLOS/889-977 ....np--LKDGYCYIRHFAEVSLSMG.RIF..FRRDV....DLGPFPYVFEVQHRLERLYGKAALRYGVRGQYSA.PRCFHCCYNDSPR-PMASFNGYhkMGG...................
#=GR Q66237_9CLOS/889-977 pAS .............*...................................................................*.........................................
Q49IH3_9CLOS/760-847 .....i-KYLNGFCYLAHCRYACAFLL.KGF..DPKRF....DIGAFPTAADLRRRMVSVLGDRSLGLNLYGAYTS.RGVFHCDYDAKYIKDLRRMSAV..IAG...................
#=GR Q49IH3_9CLOS/760-847 pAS .............*...................................................................*.........................................
Q8BEP9_9CLOS/754-841 .....d-KYKNGYCYLAHCRYASAFLL.KGF..HPAVF....DIGANPTAAKLRSRMVSVLGDRSLSLNLYGSFTS.RGIFHCDYDAAYVKDLRFMSAI..VAG...................
#=GR Q8BEP9_9CLOS/754-841 pAS .............*...................................................................*.........................................
A0A088MGX0_9CLOS/530-619 ..egsv----EGLCYLSHLNRVSLETG.VPY..RQDRAv..aILKDYPTATKLRWYVKWWFGKSALKVPLHCELNG.KNVHATSY--------------..---gsprdisgftyttrvgg..
A0A2U8JH86_9CLOS/517-602 ysapkl------KCYLNHMYFLCVINN.HVF..DEKAH....DLGSLPSSGQLLKHIARVF-PQSLNVKISGYFRR.NGNFHCELHR------------..---grlwtlkageekig.....
#=GR A0A2U8JH86_9CLOS/517-602 pAS .............*...................................................................*.........................................
A0A0K1HRG5_9CLOS/430-524 ....ys--APAGLCYLNHIWFLCLIAG.HSF..NPARAyfsrGLGRFPRFSNFLGLVERYFSYPATRVSIKGYFSR.ENLFHCDNFKGRLHS-------..---lsynrinranigg......
#=GR A0A0K1HRG5_9CLOS/430-524 pAS .............*...................................................................*.........................................
Q0GK55_9CLOS/559-651 ....re--FAEGYCYMNFLYYTSLTVN.RPFgvFTAMK....TLGKFPTATKLLWFIRSRFGGPGRKILVRGHFTSnKKIFHVDSTSSRIYNLAKMGYTvrVGG...................
#=GR Q0GK55_9CLOS/559-651 pAS .............*...................................................................*.........................................
A0A0A0P6V8_9CLOS/367-458 ....yt--APRGRCYLNHVWFLCLRAG.CAF..WPAMKf.fsRLGLNPLASDFSFYVSAYFGCAASKLFIAGRYTG.FNKFHCDNSSRRLYSLSYLRN-..---anvga..............
#=GR A0A0A0P6V8_9CLOS/367-458 pAS .............*...................................................................*.........................................
#=GC seq_cons .....t...tcGhCYLsHlaalslhhG.+sF..ppuch....sLGtaPosspltthlsphFG.pAhclsl+Gtaou.tslFHCDhss....sh..............................
//
